101. Assessment of the Effectiveness of Pharmacotherapy Follow-up in Patients Treated for Depression
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Luciene Alves Moreira Marques, Maria Rosana Fernandes, Cristiane Carneiro Oliveira Oliveira, Ana Regina Noto, Luiz Alberto Beijo, and José Carlos Fernandes Galduróz
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Adult ,medicine.medical_specialty ,Adolescent ,Pharmaceutical Science ,Pharmacy ,law.invention ,Young Adult ,Pharmacotherapy ,Randomized controlled trial ,law ,Diabetes mellitus ,Internal medicine ,Outcome Assessment, Health Care ,medicine ,Humans ,Young adult ,Depression (differential diagnoses) ,Aged ,Depressive Disorder, Major ,business.industry ,Health Policy ,Continuity of Patient Care ,Middle Aged ,medicine.disease ,Clinical pharmacy ,Physical therapy ,Anxiety ,Female ,medicine.symptom ,business ,Dyslipidemia ,Brazil - Abstract
BAckgroun D: Several studies have established the effectiveness of pharmaceutical care (Pc) in patients with heart failure, diabetes, hyperten sion, and dyslipidemia. However, there are few studies using standardized methods, e.g., randomized controlled trials, to assess the effectiveness of pharmacotherapy follow-up (PF) in patients with depression. oBjEcTiv E: To assess the effectiveness of P c via PF according to the Dader Method in female patients diagnosed with depression. METHoDS: Sixty-eight patients were selected and randomly allocated to groups, stratified by age, type of medication, severity of depression, and presence of recurrence and/or relapse. Patients in the intervention group ( ig) received clinical pharmacy intervention at monthly visits over a 3-month follow-up period. The control group (cg) also received monthly visits from the pharmacist, but PF intervention was not performed. rESul TS: A comparison of the effects of usual treatment ( cg) and Pc (ig) on depressive symptoms showed a statistically significant difference between groups, with a median reduction in Beck Depression i nventory score (Δ) of 2.5 points in the cg and 13.5 points in the ig . Similarly, sta tistically significant results were observed for anxiety symptoms, with a median reduction in Beck Anxiety i nventory score ( Δ) of 3.5 points in the cg and 13.0 points in the ig . The patients who underwent PF showed a high level of satisfaction with the service. conclu Sion: The PF is well accepted and effective in treating depressed patients, as indicated by the reduction of the depressive and anxious symptoms.