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102. Correction: YY1 Complex Promotes Quaking Expression via Super-Enhancer Binding during EMT of Hepatocellular Carcinoma

Author

Han, Jingxia, primary, Meng, Jing, additional, Chen, Shuang, additional, Wang, Xiaorui, additional, Yin, Shan, additional, Zhang, Qiang, additional, Liu, Huijuan, additional, Qin, Rong, additional, Li, Zhongwei, additional, Zhong, Weilong, additional, Zhang, Chao, additional, Zhang, Heng, additional, Tang, Yuanhao, additional, Gao, Wanfeng, additional, Zhang, Xiaoyun, additional, Yang, Lan, additional, Liu, Yanrong, additional, Zhou, Hong-gang, additional, Sun, Tao, additional, and Yang, Cheng, additional

Published
2022
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105. Pyroptosis: A possible link between obesity‐related inflammation and inflammatory diseases

Author

Yuan Huan, Sun Chao, Sun Zhuwen, Liu Yongnian, Liu Yanrong, Pan Miao, Tai Ruiqing, and Wu Qiong

Subjects
Inflammation, Programmed cell death, Inflammasomes, Physiology, business.industry, Clinical Biochemistry, Pyroptosis, Inflammasome, Cell Biology, medicine.disease, Obesity, Proinflammatory cytokine, Pathogenesis, Insulin resistance, NLR Family, Pyrin Domain-Containing 3 Protein, Immunology, medicine, Humans, medicine.symptom, business, medicine.drug
Abstract

The main manifestation of obesity is persistent low-level inflammation and insulin resistance, which is an important factor inducing or promoting other obesity-related diseases. As a proinflammatory programmed cell death, pyroptosis plays an important role, especially in the activation and regulation of the NLRP3 inflammasome pathway. Pyroptosis is associated with the pathogenesis of many chronic inflammatory diseases and is characterized by the formation of micropores in the plasma membrane and the release of a large number of proinflammatory cytokines. This article mainly introduces the main pathways and key molecules of pyroptosis and focuses on the phenomenon of pyroptosis in obesity. It is suggested that the regulation of pyroptosis-related targets may become a new potential therapy for the prevention and treatment of systemic inflammatory response caused by obesity, and we summarize the potential molecular substances that may be beneficial to obesity-related inflammatory diseases through target pyroptosis.

Published
2021

109. Retraction Notice to: Tumor cell-secreted exosomal miR-22-3p inhibits transgelin and induces vascular abnormalization to promote tumor budding

Author

Feng, Yaju, primary, Wang, Lumeng, additional, Wang, Ting, additional, Li, Ying, additional, Xun, Qingqing, additional, Zhang, Renya, additional, Liu, Lin, additional, Li, Lei, additional, Wang, Wei, additional, Tian, Yixuan, additional, Yang, Lili, additional, Zhi, Xiao, additional, Zhou, Bijiao, additional, Chen, Xin, additional, Sun, Tao, additional, and Liu, Yanrong, additional

Published
2022
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112. Correction: RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway

Author

Qiao, Kailiang, primary, Liu, Yantao, additional, Xu, Zheng, additional, Zhang, Haohao, additional, Zhang, Heng, additional, Zhang, Chao, additional, Chang, Zhi, additional, Lu, Xinyan, additional, Li, Zhongwei, additional, Luo, Ce, additional, Liu, Yanrong, additional, Yang, Cheng, additional, and Sun, Tao, additional

Published
2022
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118. Genome-wide identification and analysis of TCP family genes in Medicago sativa reveal their critical roles in Na+/K+ homeostasis.

Author

Zhang, Mingxiao, Qin, Shangqian, Yan, Jianping, Li, Lin, Xu, Mingzhi, Liu, Yanrong, and Zhang, Wanjun

Subjects
ALFALFA, GENE families, HOMEOSTASIS, PLANT growth, PLANT development, ABIOTIC stress, TRANSCRIPTION factors
Abstract

Background: Medicago sativa is the most important forage world widely, and is characterized by high quality and large biomass. While abiotic factors such as salt stress can negatively impact the growth and productivity of alfalfa. Maintaining Na+/K+ homeostasis in the cytoplasm helps reduce cell damage and nutritional deprivation, which increases a salt-tolerance of plant. Teosinte Branched1/ Cycloidea/ Proliferating cell factors (TCP) family genes, a group of plant-specific transcription factors (TFs), involved in regulating plant growth and development and abiotic stresses. Recent studies have shown TCPs control the Na+/K+ concentration of plants during salt stress. In order to improve alfalfa salt tolerance, it is important to identify alfalfa TCP genes and investigate if and how they regulate alfalfa Na+/K+ homeostasis. Results: Seventy-one MsTCPs including 23 non-redundant TCP genes were identified in the database of alfalfa genome (C.V XinJiangDaYe), they were classified into class I PCF (37 members) and class II: CIN (28 members) and CYC/TB1 (9 members). Their distribution on chromosome were unequally. MsTCPs belonging to PCF were expressed specifically in different organs without regularity, which belonging to CIN class were mainly expressed in mature leaves. MsTCPs belongs to CYC/TB1 clade had the highest expression level at meristem. Cis-elements in the promoter of MsTCPs were also predicted, the results indicated that most of the MsTCPs will be induced by phytohormone and stress treatments, especially by ABA-related stimulus including salinity stress. We found 20 out of 23 MsTCPs were up-regulated in 200 mM NaCl treatment, and MsTCP3/14/15/18 were significantly induced by 10 μM KCl, a K+ deficiency treatment. Fourteen non-redundant MsTCPs contained miR319 target site, 11 of them were upregulated in MIM319 transgenic alfalfa, and among them four (MsTCP3/4/10A/B) genes were directly degraded by miR319. MIM319 transgene alfalfa plants showed a salt sensitive phenotype, which caused by a lower content of potassium in alfalfa at least partly. The expression of potassium transported related genes showed significantly higher expression in MIM319 plants. Conclusions: We systematically analyzes the MsTCP gene family at a genome-wide level and reported that miR319-TCPs model played a function in K+ up-taking and/ or transportation especially in salt stress. The study provide valuable information for future study of TCP genes in alfalfa and supplies candidate genes for salt-tolerance alfalfa molecular-assisted breeding. [ABSTRACT FROM AUTHOR]

Published
2023
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131. A Robust Squarate-Cobalt Metal–Organic Framework for CO2/N2Separation

Author

Zhang, Lei, He, Ziyu, Liu, Yupeng, You, Jianjun, Lin, Lang, Jia, Jihui, Chen, Song, Hua, Nengbin, Ma, Li-An, Ye, Xiaoyun, Liu, Yanrong, Chen, Cheng-Xia, and Wang, Qianting

Abstract

The separation of CO2from the industrial post-combustion flue gas is of great importance to reduce the increasingly serious greenhouse effect, yet highly challenging due to the extremely high stability, low cost, and high separation performance requirements for adsorbents under the practical operating conditions. Herein, we report a robust squarate-cobalt metal–organic framework (MOF), FJUT-3, featuring an ultra-small 1D square channel decorated with −OH groups, for CO2/N2separation. Remarkably, FJUT-3 not only has excellent stability under harsh chemical conditions but also presents low-cost property for scale-up synthesis. Moreover, FJUT-3 shows excellent CO2separation performance under various humid and temperature conditions confirmed by the transient breakthrough experiments, thus enabling FJUT-3 with adequate potentials for industrial CO2capture and removal. The distinct CO2adsorption mechanism is well elucidated by theoretical calculations, in which the hierarchical C···OCO2, C–O···CCO2, and O–H···OCO2interactions play a vital synergistic role in the selective CO2adsorption process.

Published
2023
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141. Non-targeted screening and trimethylamine determination in Tilletia foetida-infected wheat using HS-SPME-GC-MS.

Author

Mei, Xiuming, Wu, Xiaoxiao, Zhou, Fan, Liu, Yanrong, Ji, Hanxu, Li, Yufeng, Jiang, Diyao, Yang, Miao, Xu, Jingjing, Qiang, Yuwei, Wang, Can, Zhang, Yu, and Zhang, Chi

Subjects
MEDICAL screening, WHEAT, TRIMETHYLAMINE, MASS spectrometry, BIOMARKERS, GRAIN, ORGANOPHOSPHORUS pesticides
Abstract

Common bunt disease of wheat in China is caused mainly by Tilletia foetida. However, reliable approaches for determining disease-associated biochemical markers are rarely reported. Here, a headspace-solid-phase microextraction coupled with headspace GC-tandem mass spectrometry (HS-SPME-GC-MS) was used to screen volatile substances in infected wheat, and an optimal chemical marker was selected to establish analytical methods for disease determination. Non-targeted screening of 13 volatile compounds unique to diseased wheat allowed a metabolite with rotten fish-like smell, trimethylamine (TMA), to be selected as the inspection marker. Subsequently, two analytical methodologies, HS-SPME-GC-MS and headspace gas chromatography with flame ionization detection (HS-GC-FID), were established to determinate the TMA content in wheat. The linear relationship, recovery and reproducibility of the methods were validated. The limit of detection (LOD) was 0.02 µg/kg for the former method, 5000-fold lower than that for the latter. When analysing samples, HS-SPME-GC-MS showed excellent sensitivity and allowed for the determination of 0.05% infected kernels among whole wheat grains. Therefore, TMA determination using HS-SPME-GC-MS is an effective alternative method to detect wheat common bunt disease occurring at extremely low infection rate. [ABSTRACT FROM AUTHOR]

Published
2023
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148. Petrogenesis and Ni-Cu-Co Sulfide Formation of Mafic Enclaves in Tulaergen Mafic-Ultramafic Intrusive Rocks, Eastern Tianshan, Northwest China: Implications for Liquid Immiscibility and Hydrothermal Remobilization of Platinum-Group Elements

Author

Liu Yanrong, Lv Xianbiao, and Wang Yujian

Subjects
chemistry.chemical_classification, 010504 meteorology & atmospheric sciences, Sulfide, Geochemistry, Geology, Platinum group, 010502 geochemistry & geophysics, 01 natural sciences, Hydrothermal circulation, Geophysics, chemistry, Geochemistry and Petrology, Ultramafic rock, Economic Geology, Mafic, 0105 earth and related environmental sciences, Petrogenesis
Published
2018

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