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101. Numerical simulation and optimization of Al alloy cylinder body by low pressure die casting

Author

Mi Guofa, Liu Yanlei, and Zhao Hengtao

Subjects
aluminum alloy, cylinder body, numerical simulation, optimization, Technology, Manufactures, TS1-2301
Abstract

Shrinkage defects can be formed easily at Critical location during low pressure die casting (LPDC) of aluminum alloy cylinder body. It has harmful effect on the products. Mold fi lling and solidifi cation process of a cylinder body was simulated by using of Z-CAST software. The casting method was improved based on the simulation results. In order to create effective feeding passage, the structure of casting was modifi ed by changing the location of strengthening ribs at the bottom, without causing any adverse effect on the part’s performance. Inserting copper billet at suitable location of the die is a valid way to create suitable solidifi cation sequence that is benefi cial to the feeding. Using these methods, the shrinkage defect was completely eliminated at the critical location.

Published
2008

109. An Apparatus for the Directional Spectral Emissivity Measurement in the Near Infrared Band

Author

Liu Yanlei, Yufang Liu, Kun Yu, Zhang Kaihua, and Ruirui Tong

Subjects
Materials science, Optical fiber, Spectrometer, business.industry, Astrophysics::High Energy Astrophysical Phenomena, Near-infrared spectroscopy, 02 engineering and technology, Atmospheric temperature range, 021001 nanoscience & nanotechnology, Condensed Matter Physics, law.invention, chemistry.chemical_compound, Wavelength, Optics, 020401 chemical engineering, chemistry, law, Silicon carbide, Emissivity, Black-body radiation, 0204 chemical engineering, 0210 nano-technology, business
Abstract

A measurement apparatus based on the optical fiber spectrometer is established to measure the directional spectral emissivity in the near infrared band. The sample is heated by a self-designed silicon carbide heater. The measurement angle can be adjusted from 0° to 82° by rotating the fiber collimating lens installed in a motorized rotary stage. The radiation signals of the sample and blackbody can be detected with a micro-optical fiber spectrometer in real time. The spectral emissivities of silicon wafer, silicon carbide, molybdenum, and tungsten are measured to verify the reproducibility and reliability of the apparatus. Furthermore, the directional spectral emissivity of high-purity chromium is investigated in the wavelength range from 950 nm to 1600 nm and the temperature range from 823 K to 1073 K. The influences of wavelength, temperature, and measurement angle on the spectral emissivity are analyzed in detail. It is found that the directional spectral emissivity of chromium decreases with the increasing wavelength and the temperature. The spectral emissivity of chromium rises slowly and then falls sharply with the increasing measurement angle. The combined uncertainty of emissivity measurement is evaluated, which is no more than 3 % for the wavelength and temperature range considered.

Published
2021

117. Additional file 5 of Chloroplast phylogenomics and divergence times of Lagerstroemia (Lythraceae)

Author

Dong, Wenpan, Xu, Chao, Liu, Yanlei, Shi, Jipu, Li, Wenying, and Suo, Zhili

Abstract

Additional file 5: Figure S4. Molecular phylogeny of Lagerstroemia resulting from ML (maximum likelihood) and BI (Bayesian inference) analyses using SSC regions (dataset-6). Maximum likelihood bootstrap values (BS) and posterior probabilities (PP) are shown at nodes. Branches with * indicate 100 % BS and a PP of 1.0.

Published
2021
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118. Additional file 3 of Chloroplast phylogenomics and divergence times of Lagerstroemia (Lythraceae)

Author

Dong, Wenpan, Xu, Chao, Liu, Yanlei, Shi, Jipu, Li, Wenying, and Suo, Zhili

Abstract

Additional file 3: Figure S2. Molecular phylogeny of Lagerstroemia resulting from ML (maximum likelihood) and BI (Bayesian inference) analyses using LSC regions (dataset-4). Maximum likelihood bootstrap values (BS) and posterior probabilities (PP) are shown at nodes. Branches with * indicate 100 % BS and a PP of 1.0.

Published
2021
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119. Additional file 4 of Chloroplast phylogenomics and divergence times of Lagerstroemia (Lythraceae)

Author

Dong, Wenpan, Xu, Chao, Liu, Yanlei, Shi, Jipu, Li, Wenying, and Suo, Zhili

Abstract

Additional file 4: Figure S3. Molecular phylogeny of Lagerstroemia resulting from ML (maximum likelihood) and BI (Bayesian inference) analyses using IR regions (dataset-5). Maximum likelihood bootstrap values (BS) and posterior probabilities (PP) are shown at nodes. Branches with * indicate 100 % BS and a PP of 1.0.

Published
2021
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121. Au-siRNA@ aptamer nanocages as a high-efficiency drug and gene delivery system for targeted lung cancer therapy

Author

Shanghai Jiao Tong University, National Key Research and Development Program (China), Shanghai Municipal Natural Science Foundation, National Natural Science Foundation of China, Yang, Yuming, Han, Yu, Sun, Qiuyang, Cheng, Jin, Yue, Caixia, Liu, Yanlei, Song, Jie, Jin, Weilin, Ding, Xianting, Fuente, Jesús M. de la, Ni, Jian, Wang, Xiaoqiang, Cui, Daxiang, Shanghai Jiao Tong University, National Key Research and Development Program (China), Shanghai Municipal Natural Science Foundation, National Natural Science Foundation of China, Yang, Yuming, Han, Yu, Sun, Qiuyang, Cheng, Jin, Yue, Caixia, Liu, Yanlei, Song, Jie, Jin, Weilin, Ding, Xianting, Fuente, Jesús M. de la, Ni, Jian, Wang, Xiaoqiang, and Cui, Daxiang

Abstract

[Background]: Gene and chemical therapy has become one of the rising stars in the field of molecular medicine during the last two decades. However, there are still numerous challenges in the development of efficient, targeted, and safe delivery systems that can avoid siRNA degradation and reduce the toxicity and adverse effects of chemotherapy medicine., [Results]: In this paper, a highly efficient AS1411 aptamer modified, dsDNA and MMP-2 cleavable peptide-fabricated gold nanocage vehicle, which could load doxorubicin hydrochloride (DOX) and siRNAs to achieve a combination of tumor responsive genetic therapy, chemotherapy, and photothermal treatment is presented. Our results show that this combined treatment achieved targeted gene silencing and tumor inhibition. After nearly one month of treatment with DOX-loaded Au-siRNA-PAA-AS1411 nanoparticles with one dose every three days in mice, a synergistic effect promoting the eradication of long-lived tumors was observed along with an increased survival rate of mice. The combined genetic, chemotherapeutic, and photothermal treatment group exhibited more than 90% tumor inhibition ratio (tumor signal) and a ~ 67% survival rate compared with a 30% tumor inhibition ratio and a 0% survival rate in the passive genetic treatment group., [Conclusions]: The development of nanocarriers with double-stranded DNA and MMP-2 cleavable peptides provides a new strategy for the combined delivery of gene and chemotherapy medicine. Au-siRNA-PAA-AS1411 exerts high anticancer activities on lung cancer, indicating immense potentials for clinical application.

Published
2021

126. Promoting optoelectronic properties of Cs2AgBiBr6 nanocrystals by formation of heterostructures with BiOCl nanosheets.

Author

Yang, Lei, Li, Yuping, Zhang, Wei, Liu, Yanlei, Cao, Jiacheng, Cao, Yang, Bao, Jusheng, Wang, Zhiwei, Wang, Lin, and Huang, Xiao

Subjects
HETEROSTRUCTURES, NANOSTRUCTURED materials, CESIUM compounds, OPTOELECTRONIC devices, NANOCRYSTALS, LEAD halides, LOW temperatures, PIEZOELECTRIC ceramics
Abstract

Lead halide perovskite nanocrystals and their heterostructures have achieved substantial advances in optoelectronics; however, their inherent material instability and lead toxicity have driven research on alternative material systems. Herein, solution-processable heterostructures composed of lead-free double perovskite Cs2AgBiBr6 nanocrystals and BiOCl nanosheets were prepared through a colloidal synthesis method. Defect states were present in BiOCl and benefited carrier generation, recombination and transport in Cs2AgBiBr6. As a result, the light emission of the Cs2AgBiBr6 nanocrystals was greatly enhanced at low temperatures, and the photodetector based on the Cs2AgBiBr6/BiOCl heterostructure exhibited a much improved on-off ratio compared to the device based on Cs2AgBiBr6 alone. Our work highlights the complex nature and impact of two-dimensional heterostructure assembly on the optoelectronic properties of lead-free double perovskites and demonstrates their great potential toward environmentally friendly optoelectronic devices. [ABSTRACT FROM AUTHOR]

Published
2022
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127. Deposition of Vertically Aligned Ag/Ag2S Nanoflakes on EGaIn Particles for Humidity Sensing.

Author

Liu, Yanlei, Yang, Lei, Chen, Qian, Wang, Zeyi, Yang, Zhiwei, Cao, Jiacheng, Wang, Xiaoshan, Li, Hai, and Huang, Xiao

Subjects
*HUMIDITY, *LIQUID metals, *SUBSTITUTION reactions, *HYDROPHILIC surfaces, *ELECTRIC conductivity
Abstract

Liquid metals, which possess both good electrical conductivity and liquid‐like processability, have drawn much attention recently. They are also capable of acting as synthesis templates to guide the deposition of other functional materials. Herein, through an in‐situ galvanic replacement reaction assisted by ultrasonication, core–shell EGaIn/Ag particles composed of EGaIn cores and vertically aligned Ag nanoflakes as shells were prepared; they were further sulfurized to yield ternary EGaIn/Ag/Ag2S core–shell composite particles. A humidity sensor based on EGaIn/Ag/Ag2S particles showed much higher sensing response than EGaIn and EGaIn/Ag. Such superior performance could be attributed to the n‐type semiconducting character of Ag2S allowing it to receive electrons from water molecules at low humidity, and its highly hydrophilic surface allowing it to absorb more water molecules at higher humidity so as to enable the formation of ion‐conductive paths. [ABSTRACT FROM AUTHOR]

Published
2022
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129. Temperature-Dependent Emissivity Models of Aeronautical Alloy DD6 and Modified Function for Emissivity Computation with Different Roughness

Author

Kun Yu, Liu Yanlei, Yufang Liu, Zhang Kaihua, and Yanfen Xu

Subjects
Materials science, Radiometer, 02 engineering and technology, Surface finish, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Computational physics, Wavelength, 020401 chemical engineering, Thermocouple, Absorption band, Emissivity, Calibration, Surface roughness, 0204 chemical engineering, 0210 nano-technology
Abstract

In this study, the spectral emissivity of aeronautical alloy DD6 at eight temperatures (473 K, 523 K, 573 K, 623 K, 673 K, 723 K, 773 K and 823 K) over the spectral range from 3 μm to 20 μm is systematically studied under argon condition. The multi-temperature calibration method is adopted to accurately obtain the FTIR spectrometer response, and then the improved method that eliminates the disturbances caused by background radiation is used for spectral emissivity determination. The effects of temperature, wavelength and surface roughness on the spectral emissivity of DD6 are investigated. The results show that the spectral emissivity increases with increasing temperature and decreases with increasing wavelength, and the emissivity increases with increasing surface roughness. The fitting relationship between the spectral emissivity and temperature is established, and it is found that the fitting results of the complex model are more consistent than those of other models. To verify the validity of the complex model, the temperature inferred from the model is compared with that measured by the radiometer and thermocouple directly. The modified emissivity model based on the Agababov roughness function is established to infer the spectral emissivity of samples with different surface roughness. The relative combined uncertainty of spectral emissivity is evaluated to be better than 3.2% except for the atmospheric absorption bands.

Published
2020

137. Single-Cell Microwell Platform Reveals Circulating Neural Cells as a Clinical Indicator for Patients with Blood-Brain Barrier Breakdown

Author

Zhang, Yu, primary, Warden, Antony R., additional, Ahmad, Khan Zara, additional, Liu, Yanlei, additional, He, Xijun, additional, Zheng, Minqiao, additional, Huo, Xinlong, additional, Zhi, Xiao, additional, Ke, Yuqing, additional, Li, Hongxia, additional, Yan, Sijia, additional, Su, Wenqiong, additional, Cai, Deng, additional, and Ding, Xianting, additional

Published
2021
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144. Targeted theranostics of lung cancer: PD-L1-guided delivery of gold nanoprisms with chlorin e6 for enhanced imaging and photothermal/photodynamic therapy

Author

Liu, Bin, primary, Qiao, Guanglei, additional, Han, Yu, additional, Shen, E, additional, Alfranca, Gabriel, additional, Tan, Haisong, additional, Wang, Lirui, additional, Pan, Shaojun, additional, Ma, Lijun, additional, Xiong, Wujun, additional, Liu, Yanlei, additional, and Cui, Daxiang, additional

Published
2020
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