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101. Journey time estimation and incident detection using GPS equipped probe vehicle

Author

Li, Yanying

Subjects
388.3143
Abstract

This thesis presents a study of the use of GPS equipped probe vehicle to collect traffic data on a motorway network. The performance of the GPS information in journey time estimation has been studied by comparing the results against video camera data and the various factors affecting estimation accuracy have been discussed. By discontinuing the use of Selective Availability, one of the main error sources of GPS, current positioning accuracy without Differential GPS is sufficient for journey time estimation. Two types of GPS equipped probe vehicles, active and passive, have been studied. A passive probe vehicle was considered to provide only link journey time and a minimum number of probe vehicles is required for reliable estimation. This research has studied the distribution of individual journey times and calculated the sample size of probe vehicles required in different traffic conditions. The sample size has shown to be generally stable for the same link, but may decrease in heavier traffic. The use of real-time estimates of journey time by probe vehicles has been studied for incident detection and journey time prediction. Link journey times at current time intervals and the differences in journey times between two adjacent time intervals have been shown to be bivariate-normally distributed in incident-free traffic. Outliers of the distribution were considered to be observed in incident traffic. A bivariate model has been developed for incident detection and a satisfactory detection and false alarm rates have been achieved. Journey tunes were predicted based on current observations and historic data for incident and incident-free conditions. An active probe vehicle was found to be able to determine vehicle position and speed at 1 Hz frequency over an entire journey. By analysing the speed profile of probe vehicles, journey times can be estimated from fewer probe vehicles than normally required. In this research, a fuzzy model was developed to analysis speed profiles, and journey time could be estimated using a single probe vehicle. Satisfactory estimates were obtained in both non-incident and incident conditions. Combinations of average speed and deceleration rates were used for incident detection.

Published
2004

106. Research on Energy Management Strategy of Fuel Cell Tractor Hybrid Power System.

Author

Zhao, Sixia, Gao, Zhi, Li, Xianzhe, Li, Yanying, and Xu, Liyou

Subjects
HYBRID power systems, FUEL cells, FUEL cell efficiency, ENERGY management, HYBRID systems, LITHIUM cells, TRACTORS
Abstract

In recent years, more and more attention has been paid to fuel cell-based hybrid tractors. In order to optimize the global power distribution of tractors and further improve the fuel economy and fuel cell durability of the system, this paper designs an energy management strategy to maximize external energy efficiency based on fuel cell/lithium battery/supercapacitor hybrid tractors. This strategy aims to reduce the real-time hydrogen consumption of the system while maximizing the external energy output so as to reduce the impact of load randomness on the output power of the fuel cell. Under the typical ploughing conditions of the tractor, the simulation is compared with the state machine strategy and the equivalent hydrogen consumption minimization strategy. The results show that the proposed strategy meets the power requirements of a given ploughing condition, and compared with the two traditional strategy systems, the performance characteristics of auxiliary energy are more fully exerted. It reduces the burden on fuel cells and improves the durability of fuel cells. The hydrogen consumption of the system was reduced by 11.03 g and 16.54 g, respectively, improving the overall economy of the hybrid system. [ABSTRACT FROM AUTHOR]

Published
2024
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107. Letrozole combined with rhGH treatment increases the adult height of short pubertal boys.

Author

He, Mingming, Zhang, Yanhong, Zhao, Qianqian, He, Dongye, Li, Yanying, Zhang, Mei, and Ban, Bo

Abstract

This study was performed to investigate the effectiveness of the combination of letrozole and recombinant human growth hormone (rhGH) to improve the predicted adult height (PAH) and final adult height (FAH) of Chinese short pubertal boys. In total, 171 Chinese short pubertal boys were recruited for this study. 96 of them received letrozole (2.5 mg/d) combined with rhGH (33.3–66.6 μg/kg.d), and the others received rhGH alone. Follow-up visits were conducted at 1, 3, 6, 9, and 12 months or regularly after the first treatment. During each visit, plasma samples were collected for clinical tests and biomedical analyses, all of which were performed according to standard protocols. This study was registered at www.chictr.org.cn under ID number ChiCTR1900026142. After receiving treatment for at least 3 months, 68 boys (91 %) in the rhGH therapy group and 90 (94 %) in the letrozole combined with rhGH (letrozole+rhGH) therapy group achieved an increase in PAH, with the latter treatment leading to a more effective slowing of bone age (BA) advancement. Moreover, the increased PAH showed a significant positive correlation with treatment time in both groups, and letrozole+rhGH increased the PAH to a greater degree than rhGH alone (p=0.0023). And letrozole+rhGH not only slowed the increase in BA more efficiently than rhGH therapy alone (p=0.0025), but also achieved a higher FAH (p=0.0078). Letrozole combined with rhGH treatment is a promising therapy to increase the PAH and FAH of Chinese short pubertal boys. [ABSTRACT FROM AUTHOR]

Published
2024
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111. Abstract CT219: Efficacy and safety of Low dose radiotherapy (LDRT) concurrent Atezolizumab (Atezo) plus chemotherapy as first line (1L) therapy for ES-SCLC: Primary analysis of Phase II MATCH study

Author

Zhou, Lin, primary, Sun, Jianguo, additional, Xie, Conghua, additional, Gong, Youling, additional, Huang, Meijuan, additional, Yuan, Zhiyong, additional, Wu, Lin, additional, Wang, Hui, additional, Bi, Nan, additional, Xu, Yaping, additional, Zhu, Jiang, additional, Liu, Yongmei, additional, Zhang, Yan, additional, Fan, Min, additional, Zou, Bingwen, additional, Yu, Min, additional, Li, Yanying, additional, Na, Feifei, additional, Xiu, Weigang, additional, Xu, Yong, additional, Wang, Jin, additional, Zhang, Xuanwei, additional, Xue, Jianxin, additional, and Lu, You, additional

Published
2023
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114. Clinical Manifestations, Genetic Variants and Therapeutic Evaluation in Sporadic Chinese Patients with Idiopathic Hypogonadotropic Hypogonadism

Author

He,Dongye, Sun,Hailing, Zhang,Mei, Li,Yanying, Liu,Fupeng, Zhang,Yanhong, He,Mingming, Ban,Bo, He,Dongye, Sun,Hailing, Zhang,Mei, Li,Yanying, Liu,Fupeng, Zhang,Yanhong, He,Mingming, and Ban,Bo

Abstract

Dongye He,1,2,* Hailing Sun,1 Mei Zhang,1,3 Yanying Li,1,3 Fupeng Liu,1,2 Yanhong Zhang,1,3 Mingming He,1 Bo Ban1– 3,* 1Department of Endocrinology, Genetics and Metabolism, Affiliated Hospital of Jining Medical University, Jining, 272029, People’s Republic of China; 2Medical Research Center, Affiliated Hospital of Jining Medical University, Jining, 272029, People’s Republic of China; 3Chinese Research Center for Behavior Medicine in Growth and Development, Jining, 272029, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dongye He; Bo Ban, Department of Endocrinology, Genetics and Metabolism, Affiliated Hospital of Jining Medical University, Jining, 272029, People’s Republic of China, Tel/Fax +86 0537 2903579, Email hehe0917@mail.jnmc.edu.cn; banbo2011@163.comPurpose: Genetic factors account for a large proportion of idiopathic hypogonadotropic hypogonadism (IHH) etiologies, although not necessarily a complete genetic basis. This study aimed to characterize the clinical presentations, genetic variants, and therapeutic outcomes of patients with sporadic IHH, which may be helpful for genetic counseling and treatment decisions.Patients and Methods: Eleven Chinese patients with IHH were retrospectively analyzed. Rare genetic variants were evaluated using whole-exome sequencing and bioinformatics analysis and were further classified according to the ACMG-AMP guidelines. The therapeutic responses of patients were further evaluated.Results: Six heterozygous variants of SOX10, WDR11, PROKR2, CHD7 and FGF17 were detected in five Kallmann syndrome (KS) patients, whereas two heterozygous variants of CHD7 and PROKR2 were detected in two normosmic IHH (nIHH) patients. Among these variants, a novel likely pathogenic variant in the SOX10 (c.429– 1G>C) was considered to cause the KS phenotype in patient 02, and two potential variants of uncertain significance (VUS) in CHD7 (c.3344G>A and c.7391A>G)

Published
2023

115. Crystal Plane-Orientation Dependent Phase Evolution from Precursor to Porous Intermediate Phase in the Vapor Phase Dealloying of a Co-Zn Alloy

Author

Li, Yanying, Han, Xiaocang, Lu, Zhen, Ying, Lei, Wang, Xinyao, Zeng, Yuqiao, Gao, Yi, Chen, Qing, Liu, Pan, Li, Yanying, Han, Xiaocang, Lu, Zhen, Ying, Lei, Wang, Xinyao, Zeng, Yuqiao, Gao, Yi, Chen, Qing, and Liu, Pan

Abstract

Understanding phase transitions and pore formation during vapor phase dealloying (VPD) is essential to optimize the microstructure and composition of nanoporous metals for versatile applications. Nevertheless, the underlying atomic mechanisms of phase formation and pore evolution during VPD are unknown. Using a binary gamma-CoZn precursor alloy as a prototype system, we found a two-step dealloying process. The microsized porous beta-CoZn intermediate phase that formed at the dealloying front facilitated the subsequent growth of completely dealloyed hierarchical nanoporous alpha-Co with the micropore structure of the intermediate phase. Combining aberration-corrected scanning transmission electron microscopy with energy dispersion X-ray spectrometry, we found that the intermediate phase preferentially formed on specific crystal planes of the precursor, and the vacancies generated by sublimation of Zn atoms diffused dominantly on the {110} planes of the precursor close to the intermediate phase. Theoretical calculations indicated that the energy barrier to the diffusion of Zn vacancies on the low-index {110} plane was lower than on other planes. The atomic-scale phase evolution play a key role in the subsequent evolution of the porous structure and provide deep insight into the phase transition during VPD. This insight may provide a new approach to tune the pore structure and composition of nanoporous metals by designing and regulating their intermediate phases.

Published
2023

116. Vapor Phase Dealloying Derived Nanoporous Co@CoO/RuO2 Composites for Efficient and Durable Oxygen Evolution Reaction

Author

Li, Yanying, Zhang, Qiwen, Zhao, Xiaoran, Wu, Haofei, Wang, Xinyao, Zeng, Yuqiao, Chen, Qing, Chen, Mingwei, Liu, Pan, Li, Yanying, Zhang, Qiwen, Zhao, Xiaoran, Wu, Haofei, Wang, Xinyao, Zeng, Yuqiao, Chen, Qing, Chen, Mingwei, and Liu, Pan

Abstract

The development of low-cost and effective oxygen evolution reaction (OER) electrocatalysts to expedite the slow kinetics of water splitting is crucial for increasing the efficiency of energy conversion from electricity to hydrogen fuel. Herein, 3D bicontinuous nanoporous Co@CoO/RuO2 composites with tunable sizes and chemical compositions are fabricated by introducing vapor phase dealloying of cobalt-based alloys. The influence of physical parameters on the formation of nanoporous Co substrates with various feature ligament sizes is systematically investigated. The CoO/RuO2 shell is constructed by integrating a thin layer of RuO2 on the inner surface of nanoporous Co, where the CoO interlayer is formed by annealing oxidization. The composite catalyst delivers an ultralow overpotential of 198 mV at 10 mA cm−2, Tafel slope of 57.1 mV dec−1, and long-term stability of 50 h. The superior OER activity and fast reaction kinetics are attributed to charge transfer through the coupling of Co-O-Ru bonds at the interface and the excellent nanopore connectivity, while the durability originates from the highly stable CoO/RuO2 interface. © 2023 Wiley-VCH GmbH.

Published
2023

119. A Novel Automatic Generation Control Method Based on the Large-Scale Electric Vehicles and Wind Power Integration Into the Grid

Author

Xi, Lei, Li, Haokai, Zhu, Jizhong, Li, Yanying, and Wang, Shouxiang

Abstract

In order to solve the problem of frequency instability of power system due to strong random disturbance caused by large-scale electric vehicles and wind power grid connection, an improved reinforcement learning algorithm, namely, optimistic initialized double Q, is proposed in this article from the perspective of automatic generation control. The proposed algorithm uses the optimistic initialization principle to expand the agent action exploration space, so as to prevent Q-learning from falling into local optimum by greedy strategy; meanwhile, it integrates double Q-learning to solve the problem of overestimation of action value in traditional reinforcement learning based on Q-learning. In the algorithm, the hyperparameter $\alpha _{\tau }$ is introduced to improve the learning efficiency, and the reward $b_{\tau }$ based on exploration times is introduced to increase the $Q$ value estimation to drive the exploration of the algorithm, so as to obtain the optimal solution. By simulating the two-area load frequency control model integrated with large-scale electric vehicles and the four-area interconnected power grid model integrated with large-scale wind power generation, it is verified that the proposed algorithm can obtain the global optimal solution, thus effectively solvinng the frequency instability caused by strong random disturbance in the grid-connected mode of large-scale wind power generation, and compared with many reinforcement learning algorithms, the proposed algorithm has better control performance.

Published
2024
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122. Research on Control Strategy of APSO-Optimized Fuzzy PID for Series Hybrid Tractors.

Author

Xu, Liyou, Wang, Yiting, Li, Yanying, Zhao, Jinghui, and Liu, Mengnan

Subjects
PARTICLE swarm optimization, HYBRID electric vehicles, PID controllers, ENERGY consumption, TRACTORS, ENERGY management
Abstract

Energy management strategies are crucial for improving fuel economy and reducing the exhaust emissions of hybrid tractors. The authors study a series diesel-electric hybrid tractor (SDEHT) and propose a multi-operating point Fuzzy PID control strategy (MOPFPCS) aimed to achieve better fuel economy and improved control. To further improve the vehicle economy, the adaptive particle swarm optimization method is used to optimize the key parameters of the Fuzzy PID controller. A co-simulation model in AVL-Cruise and Matlab/Simulink environment is developed for plowing mode and transportation mode. The simulation results show that under the two operation modes, the equivalent fuel consumption of the adaptive particle swarm optimization multi-operating points Fuzzy PID control strategy (APSO-MOPFPCS) is reduced by 18.3% and 15.0%, respectively, compared to the engine single-operating point control strategy (ESOPCS). Also, it was found to be reduced by 9.5% and 4.6%, respectively, compared to the MOPFPCS. [ABSTRACT FROM AUTHOR]

Published
2023
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123. Real‐world clinical analysis in 190 advanced NSCLC patients with uncommon EGFR mutations: A multi‐center study

Author

Qin, Yi, primary, Long, Yaling, additional, Tang, Yuan, additional, Tian, Yuke, additional, Li, Juan, additional, Duan, Ping, additional, Luo, Jieyan, additional, Yu, Min, additional, Li, Yanying, additional, Zhou, Xiaojuan, additional, Wang, Ke, additional, Gong, Youling, additional, Peng, Feng, additional, Zhu, Jiang, additional, Liu, Yongmei, additional, Zhou, Lin, additional, Lu, You, additional, and Huang, Meijuan, additional

Published
2023
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132. Additional file 1 of Serum triglyceride glucose index is a valuable predictor for visceral obesity in patients with type 2 diabetes: a cross-sectional study

Author

Yang, Qing, Xu, Huichao, Zhang, Hongli, Li, Yanying, Chen, Shuxiong, He, Dongye, Yang, Guangzhi, Ban, Bo, Zhang, Mei, and Liu, Fupeng

Abstract

Supplemental Table 1. The adipose tissue and clinical characteristics of male patients with different levels of BMI and TyG index Supplemental Table 2. The adipose tissue and clinical characteristics of female patients with different levels of BMI and TyG index Supplemental Fig. 1. ROC analyses of TyG-WC and TyG-WHR for VO (A) male patients; (B) female patients

Published
2023
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134. Publisher Correction: Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer

Author

Lu, You, Xue, Jianxin, Deng, Tao, Zhou, Xiaojuan, Yu, Kun, Deng, Lei, Huang, Meijuan, Yi, Xin, Liang, Maozhi, Wang, Yu, Shen, Haige, Tong, Ruizhan, Wang, Wenbo, Li, Li, Song, Jin, Li, Jing, Su, Xiaoxing, Ding, Zhenyu, Gong, Youling, Zhu, Jiang, Wang, Yongsheng, Zou, Bingwen, Zhang, Yan, Li, Yanying, Zhou, Lin, Liu, Yongmei, Yu, Min, Wang, Yuqi, Zhang, Xuanwei, Yin, Limei, Xia, Xuefeng, Zeng, Yong, Zhou, Qiao, Ying, Binwu, Chen, Chong, Wei, Yuquan, Li, Weimin, and Mok, Tony

Published
2020
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136. Biomimetic Yolk–Shell Nanocatalysts for Activatable Dual-Modal-Image-Guided Triple-Augmented Chemodynamic Therapy of Cancer

Author

Pan, Yuanbo, primary, Zhu, Yang, additional, Xu, Canxin, additional, Pan, Chunshu, additional, Shi, Yu, additional, Zou, Jianhua, additional, Li, Yanying, additional, Hu, Xueyin, additional, Zhou, Bo, additional, Zhao, Chenyang, additional, Gao, Qianqian, additional, Zhang, Jianmin, additional, Wu, Aiguo, additional, Chen, Xiaoyuan, additional, and Li, Juan, additional

Published
2022
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139. Preparation and Evaluation of Iron-Based Catalysts from Corncob for NO Reduction

Author

Guangtao Hu, Li Yanying, Huanran Wang, Xianchun Li, and He Chao

Subjects
Carbonization, Chemistry, 020209 energy, General Chemical Engineering, General Physics and Astronomy, Energy Engineering and Power Technology, Biomass, 02 engineering and technology, General Chemistry, Corncob, 01 natural sciences, 010305 fluids & plasmas, Catalysis, Reduction (complexity), Fuel Technology, Chemical engineering, Iron based, 0103 physical sciences, 0202 electrical engineering, electronic engineering, information engineering
Abstract

This paper presents a one-step method that significantly simplifies the biomass carbonization preparation with Fe0 as active catalyst. The catalyst activity was compared to that of the catalyst pre...

Published
2021

144. Abstract CT510: A phase I clinical trial of 3D-pluripotent stem cell biologics in heavily treated advanced NSCLC patients

Author

Huang, Meijuan, primary, Chen, Xiancheng, additional, Qin, Yi, additional, Long, Yaling, additional, Li, Qian, additional, Zhang, Yanna, additional, Yu, Min, additional, Hou, Panyan, additional, Liu, Nanxi, additional, Li, Yanying, additional, Yu, Yang, additional, Zhou, Xiaojuan, additional, Gong, Youling, additional, Wang, Ke, additional, Zhu, Jiang, additional, Peng, Feng, additional, Wang, Yongsheng, additional, Lu, You, additional, and Wei, Yuquan, additional

Published
2022
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149. Safety and efficacy of sintilimab in combination with SBRT and LDRT in PD-L1 positive treatment naïve-stage IV non-small cell lung cancer: A phase I study (IHC study).

Author

Xue, Jianxin, primary, Zhou, Xiaojuan, additional, Zhou, Laiyan, additional, Huang, Meijuan, additional, Gong, Youling, additional, Zou, Bingwen, additional, Zhu, Jiang, additional, Liu, Yongmei, additional, Peng, Feng, additional, Zhang, Yan, additional, Yu, Min, additional, Li, Yanying, additional, Na, Feifei, additional, Xiu, Weigang, additional, Zhang, Xuanwei, additional, Zhou, Lin, additional, Xu, Yong, additional, Wang, Jin, additional, and Lu, You, additional

Published
2022
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150. Striking effect of low-dose radiotherapy combined with PD-1 blockade on small cell lung cancer in mice and refractory patients (Achilles Study).

Author

Wang, Hui, primary, Yu, Min, additional, Na, Feifei, additional, Yin, Limei, additional, Zhou, Lin, additional, Yao, Zhuoran, additional, Pan, Xiangyu, additional, Zhang, Xuanwei, additional, Chen, Lin, additional, Li, Yanying, additional, Zou, Bingwen, additional, Gong, Youling, additional, Zhu, Jiang, additional, Liu, Yongmei, additional, Yi, Linglu, additional, Tong, Ruizhan, additional, Xue, Jianxin, additional, Huang, Meijuan, additional, Chen, Chong, additional, and Lu, You, additional

Published
2022
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