543 results on '"Levesque, Paul"'
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102. The In’s and Out’s of Ductography: A Comprehensive Review
103. Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N-[(1R)-1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311)
104. Pseudosaccharin amines as potent and selective K V 1.5 blockers
105. Assessment of cardiac function in large animal telemetry studies: Model sensitivity and historical results
106. Application of a cloud analysis program for beat to beat analysis of cardiac function in large animal telemetry
107. Functional effects of cardiac reference agents in human IPSC cardiomyocytes correlate with gene expression profile
108. 7-Oxopyrrolopyridine-derived DPP4 inhibitors—mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site
109. Providence and the Problem of Evil Richard Swinburne
110. Identification of potent tricyclic prodrug S1P1 receptor modulators.
111. Pyrrolidine amides of pyrazolodihydropyrimidines as potent and selective K V1.5 blockers
112. Studies in Gnosticism and in the Philosophy of Religion Gerald Hanratty
113. A Most Unlikely God: A Philosophical Enquiry into the Nature of God Barry Miller
114. How do large pharmaceutical companies mitigate concerns of drug-induced QT prolongation in drug discovery?
115. Assessment of target involvement in drug-induced seizures using knockout mouse hippocampal neurons and multielectrode arrays
116. The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
117. Providence and the Problem of Evil. (Summaries And Comments)
118. The Philosophical Papers of Alan Donagan Alan Donagan
119. Faces in the Clouds: A New Theory of Religion Stewart Elliott Guthrie
120. Das Selbstzitat bei Thomas Mann. Untersuchungen zum Verhältnis von Fiktion und Autobiographie in seinem Werk Gert Bruhn
121. Dihydropyrazolopyrimidines containing benzimidazoles as K V1.5 potassium channel antagonists
122. Metaphysics and Culture: The Aquinas Lecture, 1994
123. Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
124. Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778)
125. Correction to Discovery of ((S)-5-(Methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone As a Potent and Selective IKur Inhibitor
126. An in vitro assay for assessing cardiac contractility using hiPSC-derived cardiomyocytes and cellular impedance measurement
127. QT interval prolongation with a MAP kinase inhibitor following repeated dosing in telemeterized monkeys
128. Acute anesthetized measurements of right ventricular and pulmonary artery pressure in a rat model of pulmonary artery hypertension
129. Development of a nonclinical tool for generating dynamic QT beat-to-beat cloud data
130. Target related or off-target cardiovascular liabilities of receptor×agonists in telemetrized rats and knockout mice
131. Discovery and Structure-Activity Relationship (SAR) of a Series of Ethanolamine-Based Direct-Acting Agonists of Sphingosine-1-phosphate (S1P1).
132. Pyrano-[2,3 b]-pyridines as potassium channel antagonists
133. Design and SAR of selective T-type calcium channel antagonists containing a biaryl sulfonamide core
134. From 'beachers' to 'bikers' to 'birders': A peoples' history of the changes in leisure practices at Point Pelee National Park, 1960-1982 (Ontario)
135. Abstract 9642: Prolongation of AERP and APD with the Selective IKur inhibitor, BMS-394136, is Increased in the Zucker Diabetic Fatty Rat
136. Comparison of electrophysiologic properties of human iPSC and rat embryonic cardiomyocytes using Multi-electrode arrays
137. Cardiovascular liabilities of receptor X agonists using selective and non-selective compounds in telemetrized rats and knockout mice
138. Assessing seizure liability in hippocampal slices and neurons using multi-electrode arrays (MEA)
139. An analysis of safety pharmacology operations across the top 12 pharmaceutical companies
140. Protein binding and disconnects between hERG potency and QT interval prolongation
141. Discovery of ((S)-5-(Methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone As a Potent and Selective IKur Inhibitor
142. Novel model to determine regional blood flow using stable labeled microspheres
143. Assessing rate and dose-dependent sodium channel inhibition in beagle dogs as part of the cardiovascular drug safety evaluation
144. An in vitro model for assessing cardiac contractility using electrical field stimulation in isolated rat heart muscle preparations
145. Designing Effective Assessment: Principles and Profiles of Good Practice - By Trudy W. Banta, Elizabeth A. Jones, and Karen E. Black
146. Drug safety is a barrier to the discovery and development of new androgen receptor antagonists
147. QTc-interval variability in toxicology studies with cynomolgus monkeys: Impact of ECG methodology
148. Comparison of three ex vivo models for evaluating sodium channel inhibition
149. Identification of different ion channel inhibition in isolated sinoatrial node-atrial muscle tissue preparation (SA tissue) using MEA technology
150. Use of multielectrode arrays (MEA) to evaluate proarrhythmic potential of sodium and herg channel inhibitors in rabbit sinoatrial node tissue (SA)
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