142 results on '"Kovin Naidoo"'
Search Results
102. Surgery for sight: outcomes of congenital and developmental cataracts operated in Durban, South Africa
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Lene Øverland, D Parbhoo, P Gogate, A du Bryn, Prasidh Ramson, R Budhoo, Larry Benjamin, N Mkhize, Susan Levine, and Kovin Naidoo
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medicine.medical_specialty ,Visual acuity ,genetic structures ,medicine.medical_treatment ,Glaucoma ,Cataract Extraction ,Cataract ,Ophthalmic pathology ,Cataract extraction ,Neuro-ophthalmology ,South Africa ,03 medical and health sciences ,0302 clinical medicine ,Cataracts ,Correspondence ,parasitic diseases ,medicine ,Humans ,business.industry ,Retrospective cohort study ,Cataract surgery ,medicine.disease ,eye diseases ,Comprehensive eye examination ,Surgery ,Ocular oncology ,Ophthalmology ,Clinical Study ,030221 ophthalmology & optometry ,sense organs ,medicine.symptom ,business ,030217 neurology & neurosurgery - Abstract
To study the visual outcomes of congenital and developmental cataract surgery and determine variables for presentation for pediatric cataract surgery in KwaZulu Natal province of South Africa. Care-givers of children presenting with cataract to a quaternary centre were asked when they first detected the condition. The reasons for delay between detection and surgery were studied. The children underwent a comprehensive eye examination and then appropriate surgery. They were prospectively followed up for 3 months and visual acuity and stereopsis were noted. Delay in presentation for surgery and visual outcomes were co-related with demographic and clinical factors. Eighty-three non-traumatic cataract surgeries in 50 children were studied. Twenty-six (52%) were males, mean age was 3 years 10 months (SD 3yrs 4 months). The mean delay between identification and surgery was 20.7 months (SD 18 months). Twenty-six (52%) children had >15 months interval between diagnosis and surgery. Only mother’s occupation was significantly associated with delay (P=0.017). Post-surgery 17/69 (24.7%) had visual acuity ≥6/18, 20/69 (29.0%) had vision between 6/24–6/60, whereas 32/69 (46.3%) had visual acuity ≤6/60. The final vision was associated with age (P=0.031), delay between diagnosis and surgery (P
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- 2016
103. Mapping human resources for eye health in 21 countries of sub-Saharan Africa: current progress towards VISION 2020
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Jyoti Jaggernath, Alice Gilbert, Samantha Fox, Ronnie Graham, Karl Blanchet, Jennifer J. Palmer, Daksha Patel, Kovin Naidoo, Devan Pillay, and Farai Chinanayi
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sub-Saharan Africa ,Public Administration ,genetic structures ,medicine.medical_treatment ,Health Personnel ,Visual impairment ,Population ,Context (language use) ,Cataract Extraction ,Nursing ,Eye ,Blindness ,Vision 2020 ,Cataract ,Health administration ,medicine ,Humans ,education ,Low vision ,Africa South of the Sahara ,Vision, Ocular ,education.field_of_study ,Health Services Needs and Demand ,business.industry ,Research ,Eye health ,Health services research ,Public Health, Environmental and Occupational Health ,Cataract surgery ,Health Services ,eye diseases ,Ophthalmology ,Data quality ,Human resources ,Workforce ,Optometry ,medicine.symptom ,business - Abstract
Background Development of human resources for eye health (HReH) is a major focus of the Global Action Plan 2014 to 2019 to reduce the prevalence of avoidable visual impairment by 25% by the year 2019. The eye health workforce is thought to be much smaller in sub-Saharan Africa than in other regions of the world but data to support this for policy-making is scarce. We collected HReH and cataract surgeries data from 21 countries in sub-Sahara to estimate progress towards key suggested population-based VISION 2020 HReH indicators and cataract surgery rates (CSR) in 2011. Methods Routinely collected data on practitioner and surgery numbers in 2011 was requested from national eye care coordinators via electronic questionnaires. Telephone and e-mail discussions were used to determine data collection strategies that fit the national context and to verify reported data quality. Information was collected on six practitioner cadres: ophthalmologists, cataract surgeons, ophthalmic clinical officers, ophthalmic nurses, optometrists and ‘mid-level refractionists’ and combined with publicly available population data to calculate practitioner to population ratios and CSRs. Associations with development characteristics were conducted using Wilcoxon rank sum tests and Spearman rank correlations. Results HReH data was not easily available. A minority of countries had achieved the suggested VISION 2020 targets in 2011; five countries for ophthalmologists/cataract surgeons, four for ophthalmic nurses/clinical officers and two for CSR. All countries were below target for optometrists, even when other cadres who perform refractions as a primary duty were considered. The regional (sample) ratio for surgeons (ophthalmologists and cataract surgeons) was 2.9 per million population, 5.5 for ophthalmic clinical officers and nurses, 3.7 for optometrists and other refractionists, and 515 for CSR. A positive correlation between GDP and CSR as well as many practitioner ratios was observed (CSR P = 0.0042, ophthalmologists P = 0.0034, cataract surgeons, ophthalmic nurses and optometrists 0.1 > P > 0.05). Conclusions With only a minority of countries in our sample having reached suggested ophthalmic cadre targets and none having reached targets for refractionists in 2011, substantially more targeted investment in HReH may be needed for VISION 2020 aims to be achieved in sub-Saharan Africa.
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- 2014
104. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
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Soumya Swaminathan, Berrak Bora Basara, Niveen M E Abu-Rmeileh, Shams Eldin Ali Hassan Khalifa, Nadim E. Karam, Jongmin Lee, Roberto Tchio Talongwa, Inga Dora Sigfusdottir, Yang Yang, Stein Emil Vollset, Joseph R. Masci, Daniel Dicker, Maysaa El Sayed Zaki, Shiwei Liu, Valentina Arsić Arsenijević, Ting Wu Chuang, Linhong Wang, Xiao Rong Wang, Bryan K. Phillips, Don C. Des Jarlais, Vasco Manuel Pedro Machado, Vasiliki Stathopoulou, David Phillips, Luke Nyakarahuka, Leslie T. Cooper, Sandra Nolte, Charles R. Newton, Christina Papachristou, Stephen G. Waller, Carlos Magis-Rodriguez, D. Allen Roberts, Elisabete Weiderpass, Aliya Naheed, Andre Keren, Amanda J. Mason-Jones, Karen J. Courville, Ted R. Miller, Kinnari S. Murthy, Bolajoko O. Olusanya, Tommi Vasankari, Kyle J Foreman, Gabriel Alcalá-Cerra, Yousef Khader, Lorenzo Monasta, Austine Olufemi Adeyemo, Rakhi Dandona, Sanjay Basu, Samir Soneji, Rana J. Asghar, Yohannes Adama Melaku, Rafael Alfonso-Cristancho, John Q. Wong, Yoshihiro Kokubo, Young-Ho Khang, Dhruv S. Kazi, Tom Achoki, Homie Razavi, Uche S. Uchendu, Ashish Bhalla, Ferrán Catalá-López, Peggy Pei-Chia Chiang, Kim Moesgaard Iburg, Kaire Innos, Nicholas J K Breitborde, Zacharie Tsala Dimbuene, Elena Alvarez, Vafa Rahimi-Movaghar, Qing Lan, Simon I. Hay, Kaushalendra Kumar, Ubai Alsharif, Scott B. Patten, Gelin Xu, Theo Vos, Kalpana Balakrishnan, Raghib Ali, Marcella Montico, Andrea P. Silva, Robert G. Weintraub, Timothy M. Wolock, Mohammad Ali Sahraian, Heidi J. Larson, Kingsley N. Ukwaja, Saad B. Omer, Scott Weichenthal, D. Alex Quistberg, Justin Beardsley, Chandrashekhar T Sreeramareddy, Jennifer H MacLachlan, Hsien-Ho Lin, H. Dean Hosgood, Karzan Abdulmuhsin Mohammad, Ryan M Barber, Ibrahim Abubakar, Irma Khonelidze, Ileana B. Heredia Pi, Cyrus Cooper, Hilton Lam, Urbano Fra Paleo, Joshua A. Salomon, Ricky Leung, Farshad Pourmalek, Robert G. Nelson, Konstantinos Stroumpoulis, Megan Coggeshall, Mazin J. Al Kahbouri, Richard G. Ellenbogen, Hwashin Hyun Shin, Ida Kankindi, Guohong Jiang, Yanping Wang, Daniel Obadare Fijabi, Carlos A Castañeda-Orjuela, Chakib Nejjari, Diego De Leo, Rashmi Gupta, Gene F. Kwan, Johanna M. Geleijnse, Kenji Shibuya, Hassan Amini, Nsanzimana Sabin, Benjamin C Cowie, Karen M. Tabb, Chanda Kulkarni, Jed D. Blore, Amado D Quezada, Norito Kawakami, Walid Ammar, Van C. Lansingh, François Alla, Seyed-Mohammad Fereshtehnejad, Yichong Li, Vineet K. Chadha, Jasvinder A. Singh, Agnes Binagwaho, Andrew L. Thorne-Lyman, Denis Nash, Palwasha Anwari, Mohammad T Mashal, Kim Yun Jin, Steven E. Lipshultz, Veena S. Kulkarni, Amitava Banerjee, Naohiro Yonemoto, James D. Wilkinson, Aslam Pervaiz, Emilie Agardh, Barthelemy Kuate Defo, Alan D. Lopez, Carl Abelardo T. Antonio, Abraham D. Flaxman, Boris I. Pavlin, Karen Sliwa, Dima M. Qato, G Anil Kumar, Lynne Gaffikin, K.M. Venkat Narayan, Luca Ronfani, Kazem Rahimi, Vivekanand Jha, Gokalp Kadri Yentur, Wagner Marcenes, Giuseppe Remuzzi, Anwar Rafay, Anand Dayama, Robert Quentin Reilly, Alaa Badawi, Selen Begüm Uzun, James Leigh, Vinay Nangia, Ivy Shiue, J Brown, Nobhojit Roy, Genesis May J. Samonte, Edward J Mills, Soewarta Kosen, Atsushi Goto, Sajjad Ur Rahman, Jose C. Adsuar, Semaw Ferede Abera, Jefferson Traebert, Amiran Gamkrelidze, Andrew H. Kemp, Vasiliy Victorovich Vlassov, André Karch, Edgar P. Simard, Aref A. Bin Abdulhak, Samath D Dharmaratne, Ione Jayce Ceola Schneider, Andre Pascal Kengne, Corine Karema, Harish Chander Gugnani, Reza Assadi, Glen Mola, Paulo A. Lotufo, Christopher J L Murray, Rajeev Gupta, Philimon Gona, Mustafa Z. Younis, Herbert C. Duber, Mitchell T. Wallin, Arjun Lakshmana Balaji, Max Petzold, Francesco Saverio Violante, Monika Sawhney, Kovin Naidoo, Mercedes Colomar, Chuanhua Yu, Mitsuru Mukaigawara, Emerito Jose A. Faraon, Jung-Chen Chang, A Artaman, Muhammad Imran Nisar, Dickens Akena, Xiao Nong Zou, Knud Juel, Mohammed I. Albittar, Mohammad Yahya Saeedi, Sergey Petrovich Ermakov, Ole Frithjof Norheim, Graeme J. Hankey, Jerry Puthenpurakal Abraham, Mouhanad Hammami, Zulfiqar A Bhutta, Rintaro Mori, Maia Kereselidze, Josep Maria Haro, Emily Dansereau, Michael Brainin, Elizabeth Glaser, Ziad A. Memish, Anders Larsson, Solomon Meseret Woldeyohannes, Azmeraw T. Amare, Louisa Degenhardt, Yuichiro Yano, Luke D. Knibbs, Sadaf G. Sepanlou, Hilda L Harb, In-Hwan Oh, Katherine B Gibney, Abdullah Sulieman Terkawi, Adansi A. Amankwaa, Nicholas Graetz, Fortuné Gbètoho Gankpé, Vincent Nowaseb, David M. Pereira, Alan J Thomson, Miguel Angel Alegretti, Rupak Shivakoti, Adnan M. Durrani, Dipan Bose, Saleem M Rana, Mohammad Taghi Hedayati, Mohsen Naghavi, Vegard Skirbekk, Walter Mendoza, Ali H. Mokdad, Soraya Seedat, Zewdie Aderaw Alemu, Edson Serván-Mori, Anil Kaul, Foad Abd-Allah, Paul S. F. Yip, Marek Majdan, Peter A. Meaney, Kebede Deribe, Paul N. Jensen, Fabiola Mejía-Rodríguez, Bradford D. Gessner, Ami R. Moore, Marie Ng, Maigeng Zhou, Mohammad H. Forouzanfar, John J Huang, Tim Driscoll, Samia Alhabib, Jun Zhu, Michael H. Criqui, Eduardo Bernabé, Lalit Dandona, Miltiadis K. Tsilimbaris, Borja del Pozo-Cruz, Johan Ärnlöv, Luigi Naldi, Tariku Jibat Beyene, Rasmus Havmoeller, Bongani M. Mayosi, Konrad Pesudovs, Richard A. White, Ejaz Ahmad Khan, Orish Ebere Orisakwe, Graça Maria Ferreira De Lima, Yang Liu, Haidong Wang, Yongmei Li, Bryan L. Sykes, Ronny Westerman, Vinod K. Paul, Angel J Paternina Caicedo, Abigail C. McKay, Eric L. Ding, Narayanaswamy Venketasubramanian, Uur Dilmen, Stephen S Lim, Andrew Vallely, Alireza Esteghamati, Seok Jun Yoon, John Hornberger, Kathryn H. Jacobsen, Yong Zhao, Thomas D. Fleming, Nelson Alvis-Guzman, Damian G Hoy, Hebe N. Gouda, Mall Leinsalu, Elizabeth Johnson, Wilkister N. Moturi, Bach Xuan Tran, Donald H. Silberberg, Yingfeng Zheng, Lydia S. Atkins, Hans W. Hoek, Muluken Dessalegn, David C. Schwebel, Christopher C. Mapoma, Jost B. Jonas, Tolesa Bekele, Ibrahim Abdelmageem Mohamed Ginawi, Bulat Idrisov, Man Mohan Mehndiratta, Thomas N. Williams, Jeffrey A. Towbin, Caterina Guinovart, Jeyaraj D Pandian, Panniyammakal Jeemon, Taavi Lai, Haidong Kan, Tasara T. Mazorodze, Murugesan Raju, Randah R. Hamadeh, Neil Pearce, Melvin Barrientos Marzan, Nima Hafezi-Nejad, John Nelson Opio, Deena Alasfoor, Peter J. Hotez, Jonas Minet Kinge, Peter J. Allen, Eric Y. Tenkorang, Sudan Prasad Neupane, Laith J. Abu-Raddad, Katrina F Ortblad, Arsène Kouablan Adou, Farshad Farzadfar, Sergey Soshnikov, Neeraj Bhala, Sara Sheikhbahaei, Kyle R. Heuton, Michelle L. Bell, Yohannes Kinfu, Takayoshi Ohkubo, Belinda K Lloyd, R. Kumar, Jan Hendrik Richardus, Benjamin O. Anderson, Cell biology, Epidemiology, Public Health, Erasmus MC other, Pathology, Cardiothoracic Surgery, Murray, Christopher J.L, Ortblad, Katrina F., Guinovart, Caterina, Lim, Stephen S., Wolock, Timothy M., Roberts, D. Allen, Dansereau, Emily A., Graetz, Nichola, Barber, Ryan M., Brown, Jonathan C., Wang, Haidong, Duber, Herbert C., Naghavi, Mohsen, Dicker, Daniel, Dandona, Lalit, Salomon, Joshua A., Heuton, Kyle R., Foreman, Kyle, Phillips, David E., Fleming, Thomas D., Flaxman, Abraham D., Phillips, Bryan K., Johnson, Elizabeth K., Coggeshall, Megan S., Abd-Allah, Foad, Abera, Semaw Ferede, Abraham, Jerry P., Abubakar, Ibrahim, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen Me, Achoki, Tom, Adeyemo, Austine Olufemi, Adou, Arsène Kouablan, Adsuar, José C., Agardh, Emilie Elisabet, Akena, Dicken, Al Kahbouri, Mazin J., Alasfoor, Deena, Albittar, Mohammed I., Alcalá-Cerra, Gabriel, Alegretti, Miguel Angel, Alemu, Zewdie Aderaw, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, Francoi, Allen, Peter J., Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amankwaa, Adansi A., Amare, Azmeraw T., Amini, Hassan, Ammar, Walid, Anderson, Benjamin O., Antonio, Carl Abelardo T., Anwari, Palwasha, Ärnlöv, Johan, Arsic Arsenijevic, Valentina S., Artaman, Ali, Asghar, Rana J., Assadi, Reza, Atkins, Lydia S., Badawi, Alaa, Balakrishnan, Kalpana, Banerjee, Amitava, Basu, Sanjay, Beardsley, Justin, Bekele, Tolesa, Bell, Michelle L., Bernabe, Eduardo, Beyene, Tariku Jibat, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A., Bin Abdulhak, Aref, Binagwaho, Agne, Blore, Jed D., Bora Basara, Berrak, Bose, Dipan, Brainin, Michael, Breitborde, Nichola, Castañeda-Orjuela, Carlos A., Catalá-López, Ferrán, Chadha, Vineet K., Chang, Jung-Chen, Chiang, Peggy Pei-Chia, Chuang, Ting-Wu, Colomar, Mercede, Cooper, Leslie Trumbull, Cooper, Cyru, Courville, Karen J., Cowie, Benjamin C., Criqui, Michael H., Dandona, Rakhi, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Deribe, Kebede, Des Jarlais, Don C., Dessalegn, Muluken, Dharmaratne, Samath D., Dilmen, Uur, Ding, Eric L., Driscoll, Tim R., Durrani, Adnan M., Ellenbogen, Richard G., Ermakov, Sergey Petrovich, Esteghamati, Alireza, Faraon, Emerito Jose A., Farzadfar, Farshad, Fereshtehnejad, Seyed-Mohammad, Fijabi, Daniel Obadare, Forouzanfar, Mohammad H., Paleo, Urbano Fra., Gaffikin, Lynne, Gamkrelidze, Amiran, Gankpé, Fortuné Gbètoho, Geleijnse, Johanna M., Gessner, Bradford D., Gibney, Katherine B., Ginawi, Ibrahim Abdelmageem Mohamed, Glaser, Elizabeth L., Gona, Philimon, Goto, Atsushi, Gouda, Hebe N., Gugnani, Harish Chander, Gupta, Rajeev, Gupta, Rahul, Hafezi-Nejad, Nima, Hamadeh, Randah Ribhi, Hammami, Mouhanad, Hankey, Graeme J., Harb, Hilda L., Haro, Josep Maria, Havmoeller, Rasmu, Hay, Simon I., Hedayati, Mohammad T., Heredia Pi, Ileana B., Hoek, Hans W., Hornberger, John C., Hosgood, H. Dean, Hotez, Peter J., Hoy, Damian G., Huang, John J., Iburg, Kim M., Idrisov, Bulat T., Innos, Kaire, Jacobsen, Kathryn H., Jeemon, Panniyammakal, Jensen, Paul N., Jha, Vivekanand, Jiang, Guohong, Jonas, Jost B., Juel, Knud, Kan, Haidong, Kankindi, Ida, Karam, Nadim E., Karch, André, Karema, Corine Kakizi, Kaul, Anil, Kawakami, Norito, Kazi, Dhruv S., Kemp, Andrew H., Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Khader, Yousef Saleh, Khalifa, Shams Eldin Ali Hassan, Khan, Ejaz Ahmed, Khang, Young-Ho, Khonelidze, Irma, Kinfu, Yohanne, Kinge, Jonas M., Knibbs, Luke, Kokubo, Yoshihiro, Kosen, S., Kuate Defo, Barthelemy, Kulkarni, Veena S., Kulkarni, Chanda, Kumar, Kaushalendra, Kumar, Ravi B., Kumar, G. Anil, Kwan, Gene F., Lai, Taavi, Lakshmana Balaji, Arjun, Lam, Hilton, Lan, Qing, Lansingh, Van C., Larson, Heidi J., Larsson, Ander, Lee, Jong-Tae, Leigh, Jame, Leinsalu, Mall, Leung, Ricky, Li, Yichong, Li, Yongmei, De Lima, Graça Maria Ferreira, Lin, Hsien-Ho, Lipshultz, Steven E., Liu, Shiwei, Liu, Yang, Lloyd, Belinda K., Lotufo, Paulo A., Machado, Vasco Manuel Pedro, Maclachlan, Jennifer H., Magis-Rodriguez, Carlo, Majdan, Marek, Mapoma, Christopher Chabila, Marcenes, Wagner, Marzan, Melvin Barriento, Masci, Joseph R., Mashal, Mohammad Taufiq, Mason-Jones, Amanda J., Mayosi, Bongani M., Mazorodze, Tasara T., Mckay, Abigail Cecilia, Meaney, Peter A., Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Melaku, Yohannes Adama, Memish, Ziad A., Mendoza, Walter, Miller, Ted R., Mills, Edward J., Mohammad, Karzan Abdulmuhsin, Mokdad, Ali H., Mola, Glen Liddell, Monasta, Lorenzo, Montico, Marcella, Moore, Ami R., Mori, Rintaro, Moturi, Wilkister Nyaora, Mukaigawara, Mitsuru, Murthy, Kinnari S., Naheed, Aliya, Naidoo, Kovin S., Naldi, Luigi, Nangia, Vinay, Narayan, K.M. Venkat, Nash, Deni, Nejjari, Chakib, Nelson, Robert G., Neupane, Sudan Prasad, Newton, Charles R., Ng, Marie, Nisar, Muhammad Imran, Nolte, Sandra, Norheim, Ole F., Nowaseb, Vincent, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Olusanya, Bolajoko O., Omer, Saad B., Opio, John Nelson, Orisakwe, Orish Ebere, Pandian, Jeyaraj D., Papachristou, Christina, Paternina Caicedo, Angel J., Patten, Scott B., Paul, Vinod K., Pavlin, Boris Igor, Pearce, Neil, Pereira, David M., Pervaiz, Aslam, Pesudovs, Konrad, Petzold, Max, Pourmalek, Farshad, Qato, Dima, Quezada, Amado D., Quistberg, D. Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Sajjad Ur, Raju, Murugesan, Rana, Saleem M., Razavi, Homie, Reilly, Robert Quentin, Remuzzi, Giuseppe, Richardus, Jan Hendrik, Ronfani, Luca, Roy, Nobhojit, Sabin, Nsanzimana, Saeedi, Mohammad Yahya, Sahraian, Mohammad Ali, Samonte, Genesis May J., Sawhney, Monika, Schneider, Ione J.C., Schwebel, David C., Seedat, Soraya, Sepanlou, Sadaf G., Servan-Mori, Edson E., Sheikhbahaei, Sara, Shibuya, Kenji, Shin, Hwashin Hyun, Shiue, Ivy, Shivakoti, Rupak, Sigfusdottir, Inga Dora, Silberberg, Donald H., Silva, Andrea P., Simard, Edgar P., Singh, Jasvinder A., Skirbekk, Vegard, Sliwa, Karen, Soneji, Samir, Soshnikov, Sergey S., Sreeramareddy, Chandrashekhar T., Stathopoulou, Vasiliki Kalliopi, Stroumpoulis, Konstantino, Swaminathan, Soumya, Sykes, Bryan L., Tabb, Karen M., Talongwa, Roberto Tchio, Tenkorang, Eric Yeboah, Terkawi, Abdullah Sulieman, Thomson, Alan J., Thorne-Lyman, Andrew L., Towbin, Jeffrey A., Traebert, Jefferson, Tran, Bach X., Tsala Dimbuene, Zacharie, Tsilimbaris, Miltiadi, Uchendu, Uche S., Ukwaja, Kingsley N., Uzun, Selen Begüm, Vallely, Andrew J., Vasankari, Tommi J., Venketasubramanian, N., Violante, Francesco S., Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Waller, Stephen, Wallin, Mitchell T., Wang, Linhong, Wang, Xiao Rong, Wang, Yanping, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G., Westerman, Ronny, White, Richard A., Wilkinson, James D., Williams, Thomas Neil, Woldeyohannes, Solomon Meseret, Wong, John Q., Xu, Gelin, Yang, Yang C., Yano, Yuichiro, Yentur, Gokalp Kadri, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa, Yu, Chuanhua, Jin, Kim Yun, El Sayed Zaki, Maysaa, Zhao, Yong, Zheng, Yingfeng, Zhou, Maigeng, Zhu, Jun, Zou, Xiao Nong, Lopez, Alan D., and Vos, Theo
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Gerontology ,SEVERE FEBRILE ILLNESS ,Male ,verbal autopsy ,Nutrition and Disease ,Cost effectiveness ,MILLENNIUM DEVELOPMENT GOALS ,HIV Infections ,active antiretroviral therapy ,Global Health ,COST-EFFECTIVENESS ,0302 clinical medicine ,Voeding en Ziekte ,Global health ,HIV Infection ,030212 general & internal medicine ,0303 health sciences ,ACTIVE ANTIRETROVIRAL THERAPY ,Incidence (epidemiology) ,Medicine (all) ,Incidence ,General Medicine ,Millennium Development Goals ,3. Good health ,middle-income countries ,projection package ,World Health ,VERBAL AUTOPSY ,Female ,Human ,Tuberculosis ,Tuberculosi ,PROJECTION PACKAGE ,prospective cohort ,Epidemic ,millennium development goals ,03 medical and health sciences ,Age Distribution ,Acquired immunodeficiency syndrome (AIDS) ,SDG 3 - Good Health and Well-being ,MIDDLE-INCOME COUNTRIES ,medicine ,Organizational Objective ,Humans ,Organizational Objectives ,FEMALE SEX WORKERS ,Mortality ,Sex Distribution ,Epidemics ,cost-effectiveness ,female sex workers ,030304 developmental biology ,VLAG ,business.industry ,plasmodium-falciparum malaria ,PLASMODIUM-FALCIPARUM MALARIA ,medicine.disease ,Verbal autopsy ,Malaria ,PROSPECTIVE COHORT ,severe febrile illness ,business ,Demography - Abstract
BACKGROUND: The Millennium Declaration in 2000 brought special global attention to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal (MDG) 6. The Global Burden of Disease 2013 study provides a consistent and comprehensive approach to disease estimation for between 1990 and 2013, and an opportunity to assess whether accelerated progress has occured since the Millennium Declaration.METHODS: To estimate incidence and mortality for HIV, we used the UNAIDS Spectrum model appropriately modified based on a systematic review of available studies of mortality with and without antiretroviral therapy (ART). For concentrated epidemics, we calibrated Spectrum models to fit vital registration data corrected for misclassification of HIV deaths. In generalised epidemics, we minimised a loss function to select epidemic curves most consistent with prevalence data and demographic data for all-cause mortality. We analysed counterfactual scenarios for HIV to assess years of life saved through prevention of mother-to-child transmission (PMTCT) and ART. For tuberculosis, we analysed vital registration and verbal autopsy data to estimate mortality using cause of death ensemble modelling. We analysed data for corrected case-notifications, expert opinions on the case-detection rate, prevalence surveys, and estimated cause-specific mortality using Bayesian meta-regression to generate consistent trends in all parameters. We analysed malaria mortality and incidence using an updated cause of death database, a systematic analysis of verbal autopsy validation studies for malaria, and recent studies (2010-13) of incidence, drug resistance, and coverage of insecticide-treated bednets.FINDINGS: Globally in 2013, there were 1·8 million new HIV infections (95% uncertainty interval 1·7 million to 2·1 million), 29·2 million prevalent HIV cases (28·1 to 31·7), and 1·3 million HIV deaths (1·3 to 1·5). At the peak of the epidemic in 2005, HIV caused 1·7 million deaths (1·6 million to 1·9 million). Concentrated epidemics in Latin America and eastern Europe are substantially smaller than previously estimated. Through interventions including PMTCT and ART, 19·1 million life-years (16·6 million to 21·5 million) have been saved, 70·3% (65·4 to 76·1) in developing countries. From 2000 to 2011, the ratio of development assistance for health for HIV to years of life saved through intervention was US$4498 in developing countries. Including in HIV-positive individuals, all-form tuberculosis incidence was 7·5 million (7·4 million to 7·7 million), prevalence was 11·9 million (11·6 million to 12·2 million), and number of deaths was 1·4 million (1·3 million to 1·5 million) in 2013. In the same year and in only individuals who were HIV-negative, all-form tuberculosis incidence was 7·1 million (6·9 million to 7·3 million), prevalence was 11·2 million (10·8 million to 11·6 million), and number of deaths was 1·3 million (1·2 million to 1·4 million). Annualised rates of change (ARC) for incidence, prevalence, and death became negative after 2000. Tuberculosis in HIV-negative individuals disproportionately occurs in men and boys (versus women and girls); 64·0% of cases (63·6 to 64·3) and 64·7% of deaths (60·8 to 70·3). Globally, malaria cases and deaths grew rapidly from 1990 reaching a peak of 232 million cases (143 million to 387 million) in 2003 and 1·2 million deaths (1·1 million to 1·4 million) in 2004. Since 2004, child deaths from malaria in sub-Saharan Africa have decreased by 31·5% (15·7 to 44·1). Outside of Africa, malaria mortality has been steadily decreasing since 1990.INTERPRETATION: Our estimates of the number of people living with HIV are 18·7% smaller than UNAIDS's estimates in 2012. The number of people living with malaria is larger than estimated by WHO. The number of people living with HIV, tuberculosis, or malaria have all decreased since 2000. At the global level, upward trends for malaria and HIV deaths have been reversed and declines in tuberculosis deaths have accelerated. 101 countries (74 of which are developing) still have increasing HIV incidence. Substantial progress since the Millennium Declaration is an encouraging sign of the effect of global action.FUNDING: Bill & Melinda Gates Foundation.
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- 2014
105. Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
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Karen Sliwa, Xiaofeng Liang, Vivekanand Jha, Dorairaj Prabhakaran, Rakhi Dandona, Gonghuan Yang, Xuan Che, Soewarta Kosen, Sergei Petrovich Ermakov, Ted R. Miller, Samath D Dharmaratne, Philimon Gona, Sergey Soshnikov, Atsushi Goto, Costas A. Christophi, Zacharie Tsala Dimbuene, Elena Alvarez, Yanping Wang, Peggy Pei-Chia Chiang, Mohammad H. Forouzanfar, Giancarlo Logroscino, Massimo Cirillo, Knud Juel, Johanna M. Geleijnse, Stefan Ma, Samaya Ismayilova, Karen Fern Greenwell, Michelle L. Bell, Saad B. Omer, Ademola Lukman Adelekan, Joshua A. Salomon, Dhruv S. Kazi, Jed D. Blore, Walid Ammar, Carly E Levitz, Kovin Naidoo, Solveig A. Cunningham, Stephen G. Waller, Anand Dayama, James D. Wilkinson, Vasiliki Stathopoulou, Meghan D. Mooney, Mall Leinsalu, Jonathan R. Carapetis, Paul S. F. Yip, Anders Larsson, Abbas Ali Mahdi, Hideaki Toyoshima, Guohong Jiang, Xia Wan, Chuanhua Yu, Soufiane Boufous, Ivy Shiue, Bulat Idrisov, Qing Lan, Chelsea A. Liddell, Austin E Schumacher, Valeria Caso, Nigel Bruce, Paulo A. Lotufo, Ibrahim Abubakar, Roberto Tchio Talongwa, Luke Nyakarahuka, Edward J Mills, Iuri da Costa Leite, Semaw Ferede Abera, Ana C. Garcia, Ayse Abbasoglu Ozgoren, Matthew M Coates, Konstantinos Stroumpoulis, Bradford D. Gessner, Kebede Deribe, Tommi Vasankari, Logan Sandar, Kenji Shibuya, Karen M. Tabb, Troy Jacobs, Christopher J L Murray, Chakib Nejjari, Katherine T. Lofgren, Melvin Barrientos Marzan, Haidong Wang, Joanna Moschandreas, Raimundas Lunevicius, Nataliya Foigt, Rashmi Gupta, Ziad A. Memish, Victoria Pillay-van Wyk, Randah R. Hamadeh, Azmeraw T. Amare, Lalit Dandona, Uchechukwu K.A. Sampson, Monika Sawhney, Vasiliy Victorovich Vlassov, Farhad Islami, Palwasha Anwari, Mustafa Z. Younis, Amitava Banerjee, Ruben Castro, David O. Carpenter, Karzan Abdulmuhsin Mohammad, Taavi Lai, Yousef Khader, Sara Sheikhbahaei, Atte Meretoja, Zanfina Ademi, Ivo Rakovac, Yang Yang, Hilda L Harb, Daniel Pope, Jun She, Yichong Li, Andrew L. Thorne-Lyman, Adrian Davis, Stein Emil Vollset, Andre Pascal Kengne, Henry Apfel, Mark J. Nieuwenhuijsen, John J. McGrath, Yoshihiro Kokubo, Jonas Minet Kinge, Elisabete Weiderpass, Rajiv Chowdhury, Damian G Hoy, Jürgen C Schmidt, Seyed-Mohammad Fereshtehnejad, Harish Chander Gugnani, Hywel C Williams, Karen Edmond, Peter J. Allen, Marina Shakh-Nazarova, Tom Achoki, Edmond K. Kabagambe, Naohiro Yonemoto, Jun Zhu, Simon I. Hay, Karen J. Courville, Ketevan Goginashvili, Theo Vos, Kim Yun Jin, Kawkab Shishani, Lorenzo Monasta, H. Dean Hosgood, Uʇur Dilmen, Marcella Montico, Shankuan Zhu, Ami R. Moore, Marie Ng, Maigeng Zhou, Hebe N. Gouda, Linh N Bui, Sanjay Basu, Mouhanad Hammami, Mohammad T Mashal, Bryan K. Phillips, Marissa Iannarone, Ronan A Lyons, Young-Ho Khang, Robert G. Weintraub, Luca Ronfani, Daniel Kim, Alanur Çavlin, Ferrán Catalá-López, Ronny Westerman, Maia Kereselidze, Itamar S. Santos, Reza Assadi, Hwashin Hyun Shin, Carolina Maria Teixeira, Berrak Bora Basara, David Rojas-Rueda, Abdullah Sulieman Terkawi, Adansi A. Amankwaa, Nicholas J K Breitborde, Gokalp Kadri Yentur, Kaushalendra Kumar, Daniel Obadare Fijabi, Neeraj Bedi, Robert Quentin Reilly, Ana Maria Nogales Vasconcelos, Scott Weichenthal, Mark A. Green, Selen Begüm Uzun, Mukesh Dherani, Shams Eldin Ali Hassan Khalifa, Majed Asad, Jasvinder A. Singh, Angel J Paternina Caicedo, Eric L. Ding, Jost B. Jonas, Tolesa Bekele, Alan J Thomson, Steven E. Lipshultz, Rosario Cárdenas, Sajjad Ur Rahman, George A. Mensah, Jongmin Lee, Inga Dora Sigfusdottir, Mohammad Yahya Saeedi, Magdalena M. Muszyńska, Ulrich O Mueller, Stephen S Lim, Barthelemy Kuate Defo, Alan D. Lopez, Luciano A. Sposato, G Anil Kumar, Farshad Pourmalek, Zulfiqar A Bhutta, Maysaa El Sayed Zaki, Shiwei Liu, K.M. Venkat Narayan, William Msemburi, Ting Wu Chuang, Zewdie Aderaw Alemu, Saleem M Rana, Mohammad Taghi Hedayati, Mohsen Naghavi, Vegard Skirbekk, Walter Mendoza, Ali H. Mokdad, Yohannes Kinfu, Jean de Dieu Ngirabega, Takayoshi Ohkubo, Parfait Uwaliraye, Tasara T. Mazorodze, Farshad Farzadfar, Rob E. Dorrington, Mohammad A. AlMazroa, R. Kumar, Lesley Rushton, Wang, H, Liddell, Ca, Coates, Mm, Mooney, Md, Levitz, Ce, Schumacher, Ae, Apfel, H, Iannarone, M, Phillips, B, Lofgren, Kt, Sandar, L, Dorrington, Re, Rakovac, I, Jacobs, Ta, Liang, X, Zhou, M, Zhu, J, Yang, G, Wang, Y, Liu, S, Li, Y, Ozgoren, Aa, Abera, Sf, Abubakar, I, Achoki, T, Adelekan, A, Ademi, Z, Alemu, Za, Allen, Pj, Almazroa, Ma, Alvarez, E, Amankwaa, Aa, Amare, At, Ammar, W, Anwari, P, Cunningham, Sa, Asad, Mm, Assadi, R, Banerjee, A, Basu, S, Bedi, N, Bekele, T, Bell, Ml, Bhutta, Z, Blore, J, Basara, Bb, Boufous, S, Breitborde, N, Bruce, Ng, Bui, Ln, Carapetis, Jr, Cárdenas, R, Carpenter, Do, Caso, V, Castro, Re, Catalá Lopéz, F, Cavlin, A, Che, X, Chiang, Pp, Chowdhury, R, Christophi, Ca, Chuang, Tw, Cirillo, Massimo, da Costa Leite, I, Courville, Kj, Dandona, L, Dandona, R, Davis, A, Dayama, A, Deribe, K, Dharmaratne, Sd, Dherani, Mk, Dilmen, U, Ding, El, Edmond, Km, Ermakov, Sp, Farzadfar, F, Fereshtehnejad, Sm, Fijabi, Do, Foigt, N, Forouzanfar, Mh, Garcia, Ac, Geleijnse, Jm, Gessner, Bd, Goginashvili, K, Gona, P, Goto, A, Gouda, Hn, Green, Ma, Greenwell, Kf, Gugnani, Hc, Gupta, R, Hamadeh, Rr, Hammami, M, Harb, Hl, Hay, S, Hedayati, Mt, Hosgood, Hd, Hoy, Dg, Idrisov, Bt, Islami, F, Ismayilova, S, Jha, V, Jiang, G, Jonas, Jb, Juel, K, Kabagambe, Ek, Kazi, D, Kengne, Ap, Kereselidze, M, Khader, Y, Khalifa, Se, Khang, Yh, Kim, D, Kinfu, Y, Kinge, Jm, Kokubo, Y, Kosen, S, Defo, Bk, Kumar, Ga, Kumar, K, Kumar, Rb, Lai, T, Lan, Q, Larsson, A, Lee, Jt, Leinsalu, M, Lim, S, Lipshultz, Se, Logroscino, G, Lotufo, Pa, Lunevicius, R, Lyons, Ra, Ma, S, Mahdi, Aa, Marzan, Mb, Mashal, Mt, Mazorodze, Tt, Mcgrath, Jj, Memish, Za, Mendoza, W, Mensah, Ga, Meretoja, A, Miller, Tr, Mills, Ej, Mohammad, Ka, Mokdad, Ah, Monasta, L, Montico, M, Moore, Ar, Moschandreas, J, Msemburi, Wt, Mueller, Uo, Muszynska, Mm, Naghavi, M, Naidoo, K, Narayan, Kv, Nejjari, C, Ng, M, de Dieu Ngirabega, J, Nieuwenhuijsen, Mj, Nyakarahuka, L, Ohkubo, T, Omer, Sb, Caicedo, Aj, Wyk, Vp, Pope, D, Prabhakaran, D, Rahman, Su, Rana, Sm, Reilly, Rq, Rojas Rueda, D, Ronfani, L, Rushton, L, Saeedi, My, Salomon, J, Sampson, U, Santos, I, Sawhney, M, Schmidt, Jc, Shakh Nazarova, M, She, J, Sheikhbahaei, S, Shibuya, K, Shin, Hh, Shishani, K, Shiue, I, Sigfusdottir, Id, Singh, Ja, Skirbekk, V, Sliwa, K, Soshnikov, S, Sposato, La, Stathopoulou, Vk, Stroumpoulis, K, Tabb, Km, Talongwa, Rt, Teixeira, Cm, Terkawi, A, Thomson, Aj, Thorne Lyman, Al, Toyoshima, H, Dimbuene, Zt, Uwaliraye, P, Uzun, Sb, Vasankari, Tj, Vasconcelos, Am, Vlassov, Vv, Vollset, Se, Vos, T, Waller, S, Wan, X, Weichenthal, S, Weiderpass, E, Weintraub, Rg, Westerman, R, Wilkinson, Jd, Williams, Hc, Yang, Yc, Yentur, Gk, Yip, P, Yonemoto, N, Younis, M, Yu, C, Jin, Ky, El Sayed Zaki, M, Zhu, S, Lopez, Ad, and Murray, C. J.
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trends ,Pediatrics ,medicine.medical_specialty ,Nutrition and Disease ,democracy ,Developing country ,coverage ,VDP::Medisinske fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803 ,millennium development goals ,Global Health ,survival ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,030225 pediatrics ,Voeding en Ziekte ,Infant Mortality ,Global health ,Humans ,Organizational Objectives ,Medicine ,030212 general & internal medicine ,10. No inequality ,VLAG ,business.industry ,Mortality rate ,Infant, Newborn ,1. No poverty ,Infant ,health ,General Medicine ,Millennium Development Goals ,Infant mortality ,maternal education ,3. Good health ,Secular variation ,Child mortality ,Socioeconomic Factors ,income countries ,Child, Preschool ,Child Mortality ,developing-countries ,VDP::Midical sciences: 700::Health sciences: 800::Epidemiology, medical and dental statistics: 803 ,International development ,business ,Demography ,child-mortality - Abstract
Summary Background Remarkable financial and political efforts have been focused on the reduction of child mortality during the past few decades. Timely measurements of levels and trends in under-5 mortality are important to assess progress towards the Millennium Development Goal 4 (MDG 4) target of reduction of child mortality by two thirds from 1990 to 2015, and to identify models of success. Methods We generated updated estimates of child mortality in early neonatal (age 0–6 days), late neonatal (7–28 days), postneonatal (29–364 days), childhood (1–4 years), and under-5 (0–4 years) age groups for 188 countries from 1970 to 2013, with more than 29 000 survey, census, vital registration, and sample registration datapoints. We used Gaussian process regression with adjustments for bias and non-sampling error to synthesise the data for under-5 mortality for each country, and a separate model to estimate mortality for more detailed age groups. We used explanatory mixed effects regression models to assess the association between under-5 mortality and income per person, maternal education, HIV child death rates, secular shifts, and other factors. To quantify the contribution of these different factors and birth numbers to the change in numbers of deaths in under-5 age groups from 1990 to 2013, we used Shapley decomposition. We used estimated rates of change between 2000 and 2013 to construct under-5 mortality rate scenarios out to 2030. Findings We estimated that 6·3 million (95% UI 6·0–6·6) children under-5 died in 2013, a 64% reduction from 17·6 million (17·1–18·1) in 1970. In 2013, child mortality rates ranged from 152·5 per 1000 livebirths (130·6–177·4) in Guinea-Bissau to 2·3 (1·8–2·9) per 1000 in Singapore. The annualised rates of change from 1990 to 2013 ranged from −6·8% to 0·1%. 99 of 188 countries, including 43 of 48 countries in sub-Saharan Africa, had faster decreases in child mortality during 2000–13 than during 1990–2000. In 2013, neonatal deaths accounted for 41·6% of under-5 deaths compared with 37·4% in 1990. Compared with 1990, in 2013, rising numbers of births, especially in sub-Saharan Africa, led to 1·4 million more child deaths, and rising income per person and maternal education led to 0·9 million and 2·2 million fewer deaths, respectively. Changes in secular trends led to 4·2 million fewer deaths. Unexplained factors accounted for only −1% of the change in child deaths. In 30 developing countries, decreases since 2000 have been faster than predicted attributable to income, education, and secular shift alone. Interpretation Only 27 developing countries are expected to achieve MDG 4. Decreases since 2000 in under-5 mortality rates are accelerating in many developing countries, especially in sub-Saharan Africa. The Millennium Declaration and increased development assistance for health might have been a factor in faster decreases in some developing countries. Without further accelerated progress, many countries in west and central Africa will still have high levels of under-5 mortality in 2030. Funding Bill & Melinda Gates Foundation, US Agency for International Development.
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- 2014
106. Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe: 1990-2010
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Jill E Keeffe, Maurizio Battaglia Parodi, Rupert R A Bourne, Seth Flaxman, Hugh R. Taylor, Janet L Leasher, Kovin Naidoo, Jost B. Jonas, Tien Yin Wong, Holly Price, Serge Resnikoff, Konrad Pesudovs, Richard A. White, Bourne, Rupert R. A., Jonas, Jost B., Flaxman, Seth R., Keeffe, Jill, Leasher, Janet, Naidoo, Kovin, Battaglia Parodi, Maurizio, Pesudovs, Konrad, Price, Holly, White, Richard A., Wong, Tien Y., Resnikoff, Serge, and Taylor, Hugh R.
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Developed Countrie ,Pediatrics ,medicine.medical_specialty ,Refractive error ,Visual acuity ,genetic structures ,Eye Diseases ,Epidemiology ,European Continental Ancestry Group ,Population ,Visual impairment ,Glaucoma ,Blindness ,White People ,Cellular and Molecular Neuroscience ,Public health ,medicine ,Prevalence ,Humans ,Europe, Eastern ,education ,education.field_of_study ,business.industry ,Developed Countries ,Eye Disease ,Diabetic retinopathy ,Macular degeneration ,medicine.disease ,eye diseases ,Sensory Systems ,Blindne ,Ophthalmology ,Optometry ,medicine.symptom ,Sensory System ,business ,Human - Abstract
Background: To assess prevalence and causes of blindness and vision impairment in high-income regions and in Central/Eastern Europe in 1990 and 2010., Methods: Based on a systematic review of medical literature, prevalence of moderate and severe vision impairment (MSVI; presenting visual acuity
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- 2014
107. Visual impairment and blindness due to macular diseases globally: a systematic review and meta-analysis
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Rupert R A Bourne, Konrad Pesudovs, Richard A. White, Tien Yin Wong, Holly Price, Jill E Keeffe, Kovin Naidoo, Seth Flaxman, Hugh R. Taylor, Serge Resnikoff, Janet L Leasher, and Jost B. Jonas
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Pediatrics ,medicine.medical_specialty ,Visual acuity ,genetic structures ,Visual impairment ,Visual Acuity ,Vision, Low ,Audiology ,Blindness ,Global Health ,Retinal Diseases ,Global health ,Prevalence ,Medicine ,Humans ,Macula Lutea ,business.industry ,Macular degeneration ,medicine.disease ,eye diseases ,Age-related maculopathy ,Ophthalmology ,Meta-analysis ,Ranibizumab ,medicine.symptom ,business ,Visually Impaired Persons ,medicine.drug - Abstract
To estimate the number of people visually impaired or blind due to macular diseases except those caused by diabetic maculopathy.Meta-analysis.Based on the Global Burden of Disease Study 2010 and ongoing literature research, we examined how many people were affected by vision impairment (presenting visual acuity6/18, ≥3/60) and blindness (presenting visual acuity3/60) due to macular diseases, with diabetic maculopathy excluded.In 2010, of 32.4 million blind people and 191 million vision-impaired people, 2.1 million (95% uncertainty interval [UI]: 1.9, 2.7) people were blind, and 6.0 million (95% UI: 5.2, 8.1) million were visually impaired due to macular diseases. In 2010, macular diseases caused 6.6% (95% UI: 6.0, 7.9) of all blindness and 3.1% (95% UI: 2.7, 4.0) of all vision impairment, worldwide. These figures were lower in regions with young populations than in high-income regions. Between 1990 and 2010, the number of people who were blind or visually impaired due to macular diseases increased by 36%, or 0.6 million people (95% UI: 0.5, 0.8) and by 81%, or 2.7 million (95% UI: 2.6, 3.9) people, respectively, whereas the global population increased by 30%. Age-standardized global prevalence of macula-related blindness and vision impairment in adults 50 years of age and older decreased from 0.2% (95% UI: 0.2, 0.2) in 1990 to 0.1% (95% UI: 0.1, 0.2) in 2010 and remained unchanged from 0.4% (95% UI: 0.3, 0.5) to 0.4% (95% UI: 0.4, 0.6), respectively.In 2010, 2.1 million people were blind and 6.0 million people were visually impaired due to macular diseases, except those caused by diabetic maculopathy. Of every 15 blind people, 1 was blind due to macular disease, and of every 32 visually impaired people, 1 was visually impaired due to macular disease.
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- 2014
108. Prevalence and causes of vision loss in Central and South Asia: 1990-2010
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Jost B, Jonas, Ronnie, George, Rashima, Asokan, Seth R, Flaxman, Jill, Keeffe, Janet, Leasher, Kovin, Naidoo, Konrad, Pesudovs, Holly, Price, Lingam, Vijaya, Richard A, White, Tien Y, Wong, Serge, Resnikoff, Hugh R, Taylor, Rupert R A, Bourne, and Richard, Wormald
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medicine.medical_specialty ,Refractive error ,Visual acuity ,South asia ,Eye Diseases ,medicine.medical_treatment ,Visual impairment ,Central asia ,Epidemiology ,Glaucoma ,Macula ,Blindness ,Cellular and Molecular Neuroscience ,Asian People ,Ophthalmology ,medicine ,Prevalence ,Humans ,Asia, Southeastern ,business.industry ,Cataract surgery ,medicine.disease ,Sensory Systems ,Asia, Central ,medicine.symptom ,business ,Demography - Abstract
BACKGROUND: To examine the prevalence, patterns and trends of vision impairment and its causes from 1990 to 2010 in Central and South Asia. METHODS: Based on the Global Burden of Diseases Study 2010 and ongoing literature searches, we examined prevalence and causes of moderate and severe vision impairment (MSVI ; presenting visual acuity
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- 2014
109. Access to Optometric Education: Challenges in Sub-Saharan Africa
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Brien Holden, James Loughman, Vanessa R. Moodley, and Kovin Naidoo
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Medical education ,Inequality ,Higher education ,Service delivery framework ,business.industry ,media_common.quotation_subject ,computer education ,Visual impairment ,literacy ,Sub-Saharan Africa ,Literacy ,Pedagogy ,Structured interview ,medicine ,medicine.symptom ,Location ,business ,optometric education ,media_common ,Qualitative research - Abstract
Access to education was identified as a key international priority by UNESCO as far back as 1998 when it called for “equality of access”. The profession of optometry has been challenged to educate practitioners in increasing numbers in order to meet the eye care needs. The World Health Organization reported that globally, an estimated 285 million people are visually impaired and in Sub Saharan Africa (SSA) uncorrected refractive error is the main cause of visual impairment. The number of optometrists trained on the continent is currently insufficient to meet these eye care needs with limited access to education remaining a stark reality for students. A qualitative research design framed in phenomenology was used to conduct structured interviews with academic leaders in optometry across SSA. Finance for tuition andstudent maintenance, lack of knowledge of optometry and optometrists, high admission criteria, limited spaces at institutions,poor mathematics and science results, gender inequalities and geographical location were cited as barriers to optometric education. Lack of funding was the main contributing factor for the high attrition rate from university in countries where students have to pay their own fees.Where tertiary education is free, the limited number of spaces available in the programmes was the major barrier to access to optometric education for the ever-increasing number of aspiring applicants. The profession of optometry has a key role to play in eye care service delivery in Africa. Therefore educators, policymakers and health professionals must together formulate strategies to increase access to optometric education.
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- 2014
110. Prevalence and causes of vision loss in sub- Saharan Africa: 1990-2010
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Kovin, Naidoo, Stephen, Gichuhi, María-Gloria, Basáñez, Seth R, Flaxman, Jost B, Jonas, Jill, Keeffe, Janet L, Leasher, Konrad, Pesudovs, Holly, Price, Jennifer L, Smith, Hugo C, Turner, Richard A, White, Tien Y, Wong, Serge, Resnikoff, Hugh R, Taylor, Rupert R A, Bourne, and Richard, Wormald
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medicine.medical_specialty ,Sub saharan ,Eye Diseases ,Population ,Visual impairment ,Black People ,Blindness ,Cellular and Molecular Neuroscience ,Risk Factors ,Ophthalmology ,Epidemiology ,Prevalence ,Medicine ,Humans ,education ,Africa South of the Sahara ,education.field_of_study ,business.industry ,Diabetic retinopathy ,Macular degeneration ,medicine.disease ,Sensory Systems ,Trachoma ,Glaucoma ,Lens and zonules ,Retina ,Vision ,medicine.symptom ,business ,Demography - Abstract
AIM: To estimate the magnitude, temporal trends and subregional variation in the prevalence of blindness, and moderate/severe vision impairment (MSVI) in sub-Saharan Africa. METHODS: A systematic review was conducted of published and unpublished population-based surveys as part of the Global Burden of Disease, Risk Factors and Injuries Study 2010. The prevalence of blindness and vision impairment by country and subregion was estimated. RESULTS: In sub-Saharan Africa, 52 studies satisfied the inclusion criteria. The estimated age- standardised prevalence of blindness decreased by 32% from 1.9% (95% CI 1.5% to 2.2%) in 1990 to 1.3% (95% CI 1.1% to 1.5%) in 2010 and MSVI by 25% from 5.3% (95% CI 0.2% to 0.3%) to 4.0% (95% CI 0.2% to 0.3%) over that time. However, there was a 16% increase in the absolute numbers with blindness and a 28% increase in those with MSVI. The major causes of blindness in 2010 were ; cataract 35%, other/unidentified causes 33.1%, refractive error 13.2%, macular degeneration 6.3%, trachoma 5.2%, glaucoma 4.4% and diabetic retinopathy 2.8%. In 2010, age- standardised prevalence of MSVI in Africa was 3.8% (95% CI 3.1% to 4.7%) for men and 4.2% (95% CI 3.6% to 5.3%) for women with subregional variations from 4.1% (95% CI 3.3% to 5.4%) in West Africa to 2.0% (95% CI 1.5% to 3.3%) in southern Africa for men ; and 4.7% (95% CI 3.9% to 6.0%) in West Africa to 2.3% (95% CI 1.7% to 3.8%) in southern Africa for women. CONCLUSIONS: The age-standardised prevalence of blindness and MSVI decreased substantially from 1990 to 2010, although there was a moderate increase in the absolute numbers with blindness or MSVI. Significant subregional and gender disparities exist.
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- 2014
111. Prevalence and causes of vision loss in Southeast Asia and Oceania: 1990-2010
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Rupert R A Bourne, Tien Yin Wong, Hugh R. Taylor, Jill E Keeffe, Konrad Pesudovs, Richard A. White, Kovin Naidoo, Seth Flaxman, Jb Jonas, Serge Resnikoff, Janet L Leasher, Kathy Fotis, and Holly Price
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Refractive error ,medicine.medical_specialty ,Visual acuity ,Native Hawaiian or Other Pacific Islander ,Eye Diseases ,genetic structures ,Population ,Visual impairment ,Oceania ,Glaucoma ,Southeast asian ,Blindness ,Cellular and Molecular Neuroscience ,Asian People ,Ophthalmology ,Prevalence ,Medicine ,Humans ,education ,Asia, Southeastern ,education.field_of_study ,business.industry ,Diabetic retinopathy ,Macular degeneration ,medicine.disease ,Sensory Systems ,eye diseases ,Cataract ,GBD 2010 ,Global Burden of Disease Study ,Vision loss ,medicine.symptom ,business ,Demography - Abstract
BACKGROUND: To assess prevalence and causes of vision impairment in Southeast Asia and Oceania in 1990 and 2010. METHODS: Based on a systematic review of medical literature, prevalence of moderate and severe vision impairment (MSVI ; presenting visual acuity
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- 2014
112. Causes of vision loss worldwide, 1990–2010: a systematic analysis
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Rupert R A Bourne, Seth Flaxman, Gretchen A Stevens, Jill E Keeffe, Jennifer L. Smith, Serge Resnikoff, Kovin Naidoo, Janet L Leasher, Jost B. Jonas, Hugh R. Taylor, Holly Price, Konrad Pesudovs, and Richard A. White
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Male ,visual impairment ,global data ,prevalence ,blindness ,population ,rotterdam ,glaucoma ,eye ,Refractive error ,Visual acuity ,genetic structures ,Population ,Visual impairment ,Vision Disorders ,Glaucoma ,Blindness ,Global Health ,Cataract ,Macular Degeneration ,medicine ,Humans ,education ,Trachoma ,education.field_of_study ,Diabetic Retinopathy ,business.industry ,lcsh:Public aspects of medicine ,lcsh:RA1-1270 ,General Medicine ,Diabetic retinopathy ,Macular degeneration ,medicine.disease ,eye diseases ,Optometry ,Female ,sense organs ,medicine.symptom ,business - Abstract
Summary Background Data on causes of vision impairment and blindness are important for development of public health policies, but comprehensive analysis of change in prevalence over time is lacking. Methods We did a systematic analysis of published and unpublished data on the causes of blindness (visual acuity in the better eye less than 3/60) and moderate and severe vision impairment ([MSVI] visual acuity in the better eye less than 6/18 but at least 3/60) from 1980 to 2012. We estimated the proportions of overall vision impairment attributable to cataract, glaucoma, macular degeneration, diabetic retinopathy, trachoma, and uncorrected refractive error in 1990–2010 by age, geographical region, and year. Findings In 2010, 65% (95% uncertainty interval [UI] 61–68) of 32·4 million blind people and 76% (73–79) of 191 million people with MSVI worldwide had a preventable or treatable cause, compared with 68% (95% UI 65–70) of 31·8 million and 80% (78–83) of 172 million in 1990. Leading causes worldwide in 1990 and 2010 for blindness were cataract (39% and 33%, respectively), uncorrected refractive error (20% and 21%), and macular degeneration (5% and 7%), and for MSVI were uncorrected refractive error (51% and 53%), cataract (26% and 18%), and macular degeneration (2% and 3%). Causes of blindness varied substantially by region. Worldwide and in all regions more women than men were blind or had MSVI due to cataract and macular degeneration. Interpretation The differences and temporal changes we found in causes of blindness and MSVI have implications for planning and resource allocation in eye care. Funding Bill & Melinda Gates Foundation, Fight for Sight, Fred Hollows Foundation, and Brien Holden Vision Institute.
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- 2013
113. Scaling up the delivery of refractive error services within a district health system: the KwaZulu-Natal, South Africa experience
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Yashika I Maharaj, Kesi Naidoo, Diane Wallace, Prasidh Ramson, Reshma Dabideen, and Kovin Naidoo
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Program evaluation ,medicine.medical_specialty ,Refractive error ,Referral ,Service delivery framework ,Regional Medical Programs ,Health informatics ,Health administration ,District health system ,South Africa ,Nursing ,medicine ,Humans ,Program Development ,Public health ,business.industry ,Health Policy ,Nursing research ,medicine.disease ,Refractive Errors ,Service delivery ,Primary eye health ,business ,Delivery of Health Care ,Optometry ,Program Evaluation ,Research Article - Abstract
Background In South Africa, the health service is based on a Primary Health Care (PHC) philosophy with the District Health System (DHS) as the locus of delivery. However eye care services, particularly primary eye care, refractive error and low vision, have not been prioritised accordingly. Hence the aim of the Giving Sight to KwaZulu-Natal (GSKZN) project was to integrate the delivery of eye care services into the district health system, with emphasis on addressing the need for uncorrected refractive error and low vision services. The project was implemented in the KwaZulu-Natal province, South Africa, to scale up the delivery of refractive error services utilising a four pronged approach; including advocacy, human resource development, equipment provision and research. Methods This paper is a description of the project and a retrospective analysis of data received through the course of the project from July 2007 to June 2011. Data were collected from training registers, equipment schedules and service delivery reports from institutions. Reports from the data base were then analysed and achievements in training and trends in service delivery were determined. Results Over a four year period (July 2007 and July 2011) 1004 persons received training in rendering eye health services appropriate to their level of deployment within the DHS. During the course of the project, these 1004 persons examined 1 064 087 patients. Furthermore, the total number of clinics offering primary eye care, refractive error and low vision services increased from 96 (10%) to 748 (76%). With increased numbers of PHC Nurses trained in primary eye care, a subsequent decrease of 51.08 percent was also observed in the number of patients seeking services at higher levels of care, thus streamlining eye health service delivery. Conclusion This project has shown that scaling up can occur in delivering eye health services within a health district, through a multi-faceted approach that encompasses focused training, advocacy, development of appropriate infrastructure and the development of referral criteria with clear guidelines for the management of patients.
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- 2013
114. New systematic review methodology for visual impairment and blindness for the 2010 Global Burden of Disease study
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Rupert Bourne, Holly Price, Hugh Taylor, Janet Leasher, Jill Keeffe, Julie Glanville, Pamela C. Sieving, Moncef Khairallah, Tien Yin Wong, Yingfeng Zheng, Anu Mathew, Suchitra Katiyar, Maya Mascarenhas, Gretchen A. Stevens, Serge Resnikoff, Stephen Gichuhi, Kovin Naidoo, Diane Wallace, Steven Kymes, Colleen Peters, Konrad Pesudovs, Tasanee Braithwaite, Hans Limburg, and on behalf of the Global Burden of Disease Vision Loss Expert Group
- Subjects
Gerontology ,Epidemiology ,Population ,Visual impairment ,MEDLINE ,Systematic review methodology ,Vision, Low ,Blindness ,Global Health ,Article ,Global health ,Prevalence ,Medicine ,Humans ,education ,education.field_of_study ,business.industry ,Incidence (epidemiology) ,medicine.disease ,Ophthalmology ,medicine.symptom ,business ,Visually Impaired Persons ,Medical literature ,Demography - Abstract
Purpose: To describe a systematic review of population-based prevalence studies of visual impairment (VI) and blindness worldwide over the past 32 years that informs the Global Burden of Diseases, Injuries and Risk Factors Study. Methods: A systematic review (Stage 1) of medical literature from 1 January 1980 to 31 January 2012 identified indexed articles containing data on incidence, prevalence and causes of blindness and VI. Only cross-sectional population-based representative studies were selected from which to extract data for a database of age- and sexspecific data of prevalence of four distance and one near vision loss categories (presenting and best-corrected). Unpublished data and data from studies using rapid assessment methodology were later added (Stage 2). Results: Stage 1 identified 14,908 references, of which 204 articles met the inclusion criteria. Stage 2 added unpublished data from 44 rapid assessment studies and four other surveys. This resulted in a final dataset of 252 articles of 243 studies, of which 238 (98%) reported distance vision loss categories. A total of 37 studies of the final dataset reported prevalence of mild VI and four reported near VI. Conclusion: We report a comprehensive systematic review of over 30 years of VI/blindness studies. While there has been an increase in population-based studies conducted in the 2000s compared to previous decades, there is limited information from certain regions (eg, Central Africa and Central and Eastern Europe, and the Caribbean and Latin America), and younger age groups, and minimal data regarding prevalence of near vision and mild distance VI.
- Published
- 2013
115. A population-based study of visual impairment in the Lower Tugela health district in KZN, SA
- Author
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J Jaggernath, Deborah F. Sweeney, Kovin Naidoo, and B. Holden
- Subjects
medicine.medical_specialty ,Pediatrics ,education.field_of_study ,Coloboma ,genetic structures ,business.industry ,Visual impairment ,Population ,visual impairment, blindness, refractive error, cataract, diabetic retinopathy ,Diabetic retinopathy ,Macular degeneration ,medicine.disease ,eye diseases ,Confidence interval ,lcsh:Ophthalmology ,Hypertensive retinopathy ,lcsh:RE1-994 ,Ophthalmology ,Epidemiology ,Medicine ,medicine.symptom ,business ,education - Abstract
A cross-sectional, population-based, epidemiological study of blindness and visual impairment was conducted to evaluate the prevalence of vision loss and various sight-threatening conditions in the Lower Tugela health district of the KwaZulu-Natal province, South Africa. This study was conducted on a randomly selected sample of 3444 individuals from the district. This number represented 84% of those who were visited and 80.1% of the total sample selected. The participants ranged in age from 5 to 93 years (mean of 29.2 years and a median of 20.0 years). The proportion of men to women differed between participants aged 30 years. In both age groups, women represented the majority of participants (66.5%), but the number of women to men in the older age group was approximately twice that found in the group aged less than 30 years. The difference in age between the men and women in the study was not statistically significant (p >0.5). The study revealed that 6.4% of the population studied were visually impaired. The distribution of uncorrected visual acuity was better for women than for men for both OD and OS (p = 0.000 for OD and OS). The main causes of visual impairment were refractive error (44.5%), cataract (31.2%), glaucoma (6.0%), hypertensive retinopathy (4.1%) and diabetic retinopathy (4.1%). Unilateral blindness (OD) was present in 0.78% (95% Confidence interval (CI): 0.42%-1.14%) of participants and unilateral blindness (OS) was present in 1.1% (95% CI: 0.70%-1.50%). Thirty-one participants (0.9%) were bilaterally blind with the main causes being cataracts (54.8%) and refractive error (12.9%). Glaucoma and hypertensive retinopathy were responsible for 6.4% of ..bilateral blindness. Diabetic retinopathy, other retinal conditions (coloboma) and corneal scarring were each responsible for 3.2% of bilateral blindness. Albinism, coloboma and age-related macular degeneration accounted for 9.7% of bilateral blindness. The data provides much needed information to support the planning of eye care programs in KwaZulu-Natal. (S Afr Optom 2013 72(3) 110-118)
- Published
- 2013
116. Global prevalence of vision impairment and blindness: magnitude and temporal trends, 1990-2010
- Author
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Gretchen A, Stevens, Richard A, White, Seth R, Flaxman, Holly, Price, Jost B, Jonas, Jill, Keeffe, Janet, Leasher, Kovin, Naidoo, Konrad, Pesudovs, Serge, Resnikoff, Hugh, Taylor, and Rupert R A, Bourne
- Subjects
Adult ,Male ,Adolescent ,Visual Acuity ,Infant ,Vision, Low ,Middle Aged ,Blindness ,Global Health ,Child, Preschool ,Prevalence ,Humans ,Female ,Healthcare Disparities ,Sex Distribution ,Child ,Visually Impaired Persons ,Aged - Abstract
Vision impairment is a leading and largely preventable cause of disability worldwide. However, no study of global and regional trends in the prevalence of vision impairment has been carried out. We estimated the prevalence of vision impairment and its changes worldwide for the past 20 years.Systematic review.A systematic review of published and unpublished population-based data on vision impairment and blindness from 1980 through 2012.Hierarchical models were fitted fitted to estimate the prevalence of moderate and severe vision impairment (MSVI; defined as presenting visual acuity6/18 but ≥ 3/60) and the prevalence of blindness (presenting visual acuity3/60) by age, country, and year.Trends in the prevalence of MSVI and blindness for the period 1990 through 2010.Globally, 32.4 million people (95% confidence interval [CI], 29.4-36.5 million people; 60% women) were blind in 2010, and 191 million people (95% CI, 174-230 million people; 57% women) had MSVI. The age-standardized prevalence of blindness in older adults (≥ 50 years) was more than 4% in Western Sub-Saharan Africa (6.0%; 95% CI, 4.6%-7.1%), Eastern Sub-Saharan Africa (5.7%; 95% CI, 4.4%-6.9%), South Asia (4.4%; 95% CI, 3.5%-5.1%), and North Africa and the Middle East (4.6%; 95% CI, 3.5%-5.8%), in contrast to high-income regions with blindness prevalences of ≤ 0.4% or less. The MSVI prevalence in older adults was highest in South Asia (23.6%; 95% CI, 19.4%-29.4%), Oceania (18.9%; 95% CI, 11.8%-23.7%), and Eastern and Western Sub-Saharan Africa and North Africa and the Middle East (95% CI, 15.9%-16.8%). The MSVI prevalence was less than 5% in all 4 high-income regions. The global age-standardized prevalence of blindness and MSVI for older adults decreased from 3.0% (95% CI, 2.7%-3.4%) worldwide in 1990 to 1.9% (95% CI, 1.7%-2.2%) in 2010 and from 14.3% (95% CI, 12.1%-16.2%) worldwide to 10.4% (95% CI, 9.5%-12.3%), respectively. When controlling for age, women's prevalence of blindness was greater than men's in all world regions. Because the global population has increased and aged between 1990 and 2010, the number of blind has increased by 0.6 million people (95% CI, -5.2 to 5.3 million people). The number with MSVI may have increased by 19 million people (95% CI, -8 to 72 million people) from 172 million people (95% CI, 142-198 million people) in 1990.The age-standardized prevalence of blindness and MSVI has decreased in the past 20 years. However, because of population growth and the relative increase in older adults, the blind population has been stable and the population with MSVI may have increased
- Published
- 2013
117. Global cost of correcting vision impairment from uncorrected refractive error
- Author
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Timothy R. Fricke, Brien A. Holden, Kovin Naidoo, G Schlenther, Serge Resnikoff, Kevin D. Frick, and DA Wilson
- Subjects
Research ,Cost-Benefit Analysis ,Health Personnel ,Public Health, Environmental and Occupational Health ,Humans ,Blindness ,Global Health ,Refractive Errors ,Visually Impaired Persons - Abstract
To estimate the global cost of establishing and operating the educational and refractive care facilities required to provide care to all individuals who currently have vision impairment resulting from uncorrected refractive error (URE).The global cost of correcting URE was estimated using data on the population, the prevalence of URE and the number of existing refractive care practitioners in individual countries, the cost of establishing and operating educational programmes for practitioners and the cost of establishing and operating refractive care facilities. The assumptions made ensured that costs were not underestimated and an upper limit to the costs was derived using the most expensive extreme for each assumption.There were an estimated 158 million cases of distance vision impairment and 544 million cases of near vision impairment caused by URE worldwide in 2007. Approximately 47 000 additional full-time functional clinical refractionists and 18 000 ophthalmic dispensers would be required to provide refractive care services for these individuals. The global cost of educating the additional personnel and of establishing, maintaining and operating the refractive care facilities needed was estimated to be around 20 000 million United States dollars (US$) and the upper-limit cost was US$ 28 000 million. The estimated loss in global gross domestic product due to distance vision impairment caused by URE was US$ 202 000 million annually.The cost of establishing and operating the educational and refractive care facilities required to deal with vision impairment resulting from URE was a small proportion of the global loss in productivity associated with that vision impairment.
- Published
- 2012
118. Dyslexia: An overview
- Author
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Kovin Naidoo and S. O. Wajuihian
- Subjects
Management of dyslexia ,media_common.quotation_subject ,Dyslexia ,dyslexia and optometry ,Affect (psychology) ,medicine.disease ,behavioral disciplines and activities ,Biological theories of dyslexia ,nervous system diseases ,Developmental psychology ,lcsh:Ophthalmology ,lcsh:RE1-994 ,Multidisciplinary approach ,Reading (process) ,mental disorders ,Learning disability ,medicine ,Learning to read ,reading difficulties ,medicine.symptom ,Psychology ,psychological phenomena and processes ,media_common - Abstract
Dyslexia is a neuro-developmental disorder characterized by difficulties in learning to read despite conventional instruction, adequate intelligence and a balanced sociocultural background. Dyslexia is the most common type of learning disorder. Reading difficulties affect a child’s academic achievement. As primary eye care practitioners, optometrists have a role in attending to patients who may present with symptoms indicative of dyslexia, therefore an understanding of dyslexia will be beneficial to the optometrist. This paper presents an overview of dyslexia and discusses its prevalence, aetiology, classifications, neural pathways involved in reading, theories, neuro-imaging techniques and management options. The role of optometry in the multidisciplinary management of dyslexia is discussed. (S Afr Optom 2011 70(2) 89-98)
- Published
- 2011
119. Ocular manifestations of HIV/AIDS: A literature review* (Part 1)
- Author
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Rekha Hansraj, Pirindhavellie Govender, Linda Visser, and Kovin Naidoo
- Subjects
medicine.medical_specialty ,Pathology ,education.field_of_study ,genetic structures ,business.industry ,Incidence (epidemiology) ,Population ,Prevalence ,Disease ,medicine.disease ,Dermatology ,eye diseases ,Virus ,Posterior segment of eyeball ,lcsh:Ophthalmology ,Acquired immunodeficiency syndrome (AIDS) ,lcsh:RE1-994 ,Global health ,medicine ,sense organs ,business ,education - Abstract
Human Immunodeficiency Virus (HIV), is a retrovirus which causes Acquired Immune Deficiency Syndrome (AIDS)1, 2. Since its discovery in 1981, HIV/AIDS has emerged as a global health problem3. The prevalence rate of HIV/AIDS has been reported to be 0.8% globally, 5% in Sub-Saharan Africa and 18.8% in South Africa4, 5. The impact of the HIV/AIDS pandemic has spurred much research into the disease and its various systemic and ocular complications. Maclean6 first described the ocular manifestations of HIV infection more than 20 years ago. The ocular manifestations of HIV/AIDS have been for the most part due to the opportunistic infections and neoplasias that accompany the syndrome7. The evolution of HIV and the appearance of new strains of the virus have however, changed the incidence of the disease with resultant changes in AIDS-related eye diseases and blindness. Research has indicated that anti-retroviral therapy has also modified the clinical progression of the disease8. The HIV virus has been found in the tear film and other ocular structures such as the cornea, vitreous and chorioretinal tissue9. Ocular manifestations have been reported in 70 to 100% of individuals infected with HIV10, 11. The ocular manifestations may involve the adnexae and anterior and posterior segments of the eye. In addition, HIV/ AIDS also presents with orbital and neuro-ophthalmic manifestations11. Anterior segment involvement usually results in tumours and external infections while posterior segment involvement usually results in HIV-retinopathy and a number of opportunistic infections of the retina and the choroid8. Early detection of the ocular manifestations of HIV/ AIDS is critical since these ocular manifestations may be the primary presentation of the systemic infection12. This has implications for the prognosis of the disease. It is difficult to review this topic in one article
- Published
- 2010
120. Optometric practices and practitioners in KwaZulu-Natal, South Africa*
- Author
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Khathutshelo P. Mashige and Kovin Naidoo
- Subjects
education.field_of_study ,medicine.medical_specialty ,business.industry ,Print media ,Population ,Clinical Practice ,Contact lens ,lcsh:Ophthalmology ,Continuing professional development ,lcsh:RE1-994 ,Family medicine ,Diagnostic equipment ,Optometry ,Medicine ,Rural area ,education ,business ,Kwazulu natal - Abstract
This paper presents findings of a survey of optometric practices and practitioners in the KwaZulu-Natal (KZN) province. Questions on demographics of practitioners, equipment, clinical practice andbusiness profile were included in the questionnaire. Also, issues that have the potential to impact on optometric practices were contained in the questionnaire and these include medical aid, advertising, continuous professional development (CPD) and emigration. Of the 117 completed questionnaires, 55% were from females and 45% were from male practitioners. The respondents included 55% Indians, 27% Whites, 17% Blacks and 1% Coloureds. The majority of practices were located in urban areas (90%) and rural areas (10%), and were mostly independent (67%) and franchises (33%). Only a minority of the practices had major diagnostic equipment such as visual field analysers (33%) and corneal topographers (7%). A significant proportion of the practitioners reported not routinely performing non-contact tonometry (45%) and slit lamp examination (41%) respectively. The majority (95%) rated patient’s needs as a very important factor in their decision to prescribe an optical device. A significant proportion (38%) of the practices had annual patient bases of above 33 000, with 35% having an average of 51-100 new patients per month. A few (5%) practices reported gross monthly turnovers of above R400 000, and 27% reported turnovers of less than R60 000. Many (89%) derived 41% and above of their total revenue from spectacle lens sales and 11% derived 41% and above from contact lens sales. The majority (92%) of practices were contracted to over 60% of the medical aid schemes. Many (68%) reported that they were not negatively affected by medical aid fraud committed by their colleagues, however, a significant proportion (32%) reported the converse. More than half (54%) of the practitioners reported that they used the print media
- Published
- 2010
121. The challenge of uncorrected refractive error: driving the agenda of the Durban Declaration on refractive error and service development
- Author
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Kovin Naidoo, Hannah B Faal, Palesa Dube, Brien A Holden, Hasan Minto, and Diane Wallace
- Subjects
Civil society ,Refractive error ,Economic growth ,United Nations ,Visual impairment ,Declaration ,Developing country ,Blindness ,Global Health ,World Health Organization ,South Africa ,Political science ,Global health ,medicine ,Humans ,Organizational Objectives ,Developing Countries ,Health Priorities ,Millennium Development Goals ,medicine.disease ,Refractive Errors ,Ophthalmology ,Scale (social sciences) ,Optometry ,medicine.symptom - Abstract
The purpose of this article is to highlight the challenge of uncorrected refractive error globally, as well as to discuss recent advocacy successes and innovative programs designed to address the need for broader refractive error service development, particularly in developing countries. The World Health Organization's VISION 2020: The Right to Sight program first posed the challenge to national governments to give priority to strategies and resources targeted towards avoidable causes of blindness and visual impairment, so that these unnecessary forms of blindness or visual impairment can be eliminated globally by the year 2020. The blindness prevention community is challenged to increase in scale its initiatives, which support the attainment of VISION 2020: The Right to Sight goals primarily and the United Nation's Millennium Development Goals indirectly. The Durban Declaration on Refractive Error and Service Development was the outcome of a meeting of eye-care professionals, researchers, governments, civil society and industry in March 2007 and still stands as a guiding document to the blindness prevention community for the elimination of avoidable blindness due to uncorrected refractive error.
- Published
- 2010
122. Poverty and blindness in Africa
- Author
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Kovin Naidoo
- Subjects
medicine.medical_specialty ,Economic growth ,genetic structures ,Population ,Visual impairment ,Developing country ,Blindness ,Risk Factors ,Health care ,medicine ,Prevalence ,Humans ,Human resources ,education ,Poverty ,education.field_of_study ,business.industry ,Public health ,eye diseases ,Ophthalmology ,Health promotion ,Socioeconomic Factors ,Africa ,Optometry ,Public Health ,medicine.symptom ,business - Abstract
Africa carries a disproportionate responsibility in terms of blindness and visual impairment. With approximately 10 per cent of the world's population, Africa has 19 per cent of the world's blindness. It is no surprise that this reality also mirrors the situation in terms of the burden of world poverty. There is an increasing recognition of the need to highlight the link between poverty, development and health care. Blindness, disabling visual impairment and the overall lack of eye-care services are too often the result of social, economic and developmental challenges of the developing world. The state of eye care in Africa stands in alarming contrast to that in the rest of the world. Poor practitioner-to-patient ratios, absence of eye-care personnel, inadequate facilities, poor state funding and a lack of educational programs are the hallmarks of eye care in Africa, with preventable and treatable conditions being the leading cause of blindness. Eye diseases causing preventable blindness are often the result of a combination of factors such as poverty, lack of education and inadequate health-care services. The challenge that Vision 2020 has set itself in Africa is enormous. Africa is not a homogenous entity, the inter- and intra-country differences in economic development, prevalence of disease, delivery infrastructure and human resources amplify the challenges of meeting eye-care needs. The successful implementation of Vision 2020 programs will be hindered without the development of a comprehensive, co-ordinated strategy that is cognisant of the differences that exist and the need for comprehensive solutions that are rooted in the economic and political realities of the continent as well as the individual countries and regions within countries. This strategy should recognise the need for economic growth that results in greater state funded eye-care services that focus on health promotion to ensure the prevention of eye disease, the development of eye clinics in hospitals and health clinics, and the training of the appropriate human resources.
- Published
- 2007
123. Number of People Blind or Visually Impaired by Cataract Worldwide and in World Regions, 1990 to 2010
- Author
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Tien Yin Wong, Jost B. Jonas, Rupert R A Bourne, Rim Kahloun, Serge Resnikoff, Seth Flaxman, Holly Price, Hans Limburg, Konrad Pesudovs, Richard A. White, Hugh R. Taylor, Janet L Leasher, Moncef Khairallah, Jill E Keeffe, and Kovin Naidoo
- Subjects
Male ,Moderate to severe ,medicine.medical_specialty ,Visual acuity ,genetic structures ,Visually impaired ,Visual impairment ,Visual Acuity ,Vision, Low ,Blindness ,Global Health ,Cataract ,Southeast asia ,Epidemiology ,Prevalence ,Global health ,medicine ,Humans ,Developing Countries ,Aged ,Aged, 80 and over ,business.industry ,Developed Countries ,Middle Aged ,medicine.disease ,eye diseases ,Optometry ,Female ,medicine.symptom ,business - Abstract
Purpose: To estimate prevalence and number of people visually impaired or blind due to cataract. Methods: Based on the Global Burden of Diseases Study 2010 and ongoing literature research, we examined how many people were affected by moderate to severe vision impairment (MSVI; presenting visual acuity
- Published
- 2015
124. Meta-analysis to compare the safety and efficacy of manual small incision cataract surgery and phacoemulsification
- Author
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Jyoti Jaggernath B Optom, Swapna Deshpande, Kovin Naidoo, and Parikshit Gogate
- Subjects
Male ,Microsurgery ,medicine.medical_specialty ,Biometry ,Distance visual acuity ,genetic structures ,medicine.medical_treatment ,Visual Acuity ,Statistical difference ,Cataract Extraction ,Astigmatism ,Near vision ,Postoperative Complications ,Ophthalmology ,medicine ,Humans ,Intraoperative Complications ,Phacoemulsification ,business.industry ,General Medicine ,Corneal Endothelial Cell Loss ,Cataract surgery ,medicine.disease ,eye diseases ,Surgery ,Small incision ,Vision Outcome ,Meta-analysis ,Original Article ,Manual Small Incision Cataract Surgery ,business ,Meta-Analysis - Abstract
Purpose: A systematic review and meta-analysis comparing the safety, efficacy, and expenses related to phacoemulsification versus manual small incision cataract surgery (SICS). Methods: PubMed, Cochrane, and Scopus databases were searched with key words manual SICS 6/18 and 6/60; astigmatism and endothelial cell loss postoperatively, intra- and post-operative complications, phacoemulsification, and comparison of SICS and phacoemulsification. Non-English language manuscripts and manuscripts not indexed in the three databases were also search for comparison of SICS with phacoemulsification. Data were compared between techniques for postoperative uncorrected and corrected distance visual acuity (UCVA and best corrected visual acuity [BCVA], respectively) better than 6/9, surgical cost and duration of surgery. The Oxford cataract treatment and evaluation team scores were used for grading intraoperative and postoperative complications, uncorrected near vision. Result: This review analyzed, 11 comparative studies documenting 76,838 eyes that had undergone cataract surgery considered for analysis. UCVA of 6/18 UCVA and 6/18 BCVA were comparable between techniques (P = 0.373 and P = 0.567, respectively). BCVA of 6/9 was comparable between techniques (P = 0.685). UCVA of 6/60 and 6/60 BCVA aided and unaided vision were comparable (P = 0.126 and P = 0.317, respectively). There was no statistical difference in: Endothelial cell loss during surgery (P = 0.298), intraoperative (P = 0.964) complications, and postoperative complications (P = 0.362). The phacoemulsification group had statistically significantly less astigmatism (P = 0.005) and more eyes with UCVA of 6/9 (P = 0.040). UCVA at near was statistically significantly better with SICS due to astigmatism and safer during the learning phase (P = 0.003). The average time for SICS was lower than phacoemulsification and cost
- Published
- 2015
125. Trends and implications for achieving VISION 2020 human resources for eye health targets in 16 countries of sub-Saharan Africa by the year 2020
- Author
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Jennifer J. Palmer, Samantha Fox, Jyoti Jaggernath, Farai Chinanayi, Daksha Patel, Devan Pillay, Kovin Naidoo, Ronnie Graham, Karl Blanchet, and Alice Gilbert
- Subjects
Public Administration ,genetic structures ,medicine.medical_treatment ,Health Personnel ,Population ,Visual impairment ,Cataract Extraction ,Eye ,Nursing Vision 2020 ,Cataract ,Health administration ,Medicine ,Population growth ,Humans ,Human resources ,education ,Population Growth ,Africa South of the Sahara ,Vision, Ocular ,education.field_of_study ,Health Services Needs and Demand ,Sub-Saharan Africa ,business.industry ,Research ,Eye health ,Health services research ,Public Health, Environmental and Occupational Health ,Cataract surgery ,Health Services ,Task-shifting ,eye diseases ,Ophthalmology ,Workforce ,Optometry ,medicine.symptom ,business - Abstract
Background Development of human resources for eye health (HReH) is a major global eye health strategy to reduce the prevalence of avoidable visual impairment by the year 2020. Building on our previous analysis of current progress towards key HReH indicators and cataract surgery rates (CSRs), we predicted future indicator achievement among 16 countries of sub-Saharan Africa by 2020. Methods Surgical and HReH data were collected from national eye care programme coordinators on six practitioner cadres: ophthalmologists, cataract surgeons, ophthalmic clinical officers, ophthalmic nurses, optometrists and ‘mid-level refractionists’ and combined them with publicly available population data to calculate practitioner-to-population ratios and CSRs. Data on workforce entry and exit (2008 to 2010) was used to project practitioner population and CSR growth between 2011 and 2020 in relation to projected growth in the general population. Associations between indicator progress and the presence of a non-physician cataract surgeon cadre were also explored using Wilcoxon rank sum tests and Spearman rank correlations. Results In our 16-country sample, practitioner per million population ratios are predicted to increase slightly for surgeons (ophthalmologists/cataract surgeons, from 3.1 in 2011 to 3.4 in 2020) and ophthalmic nurses/clinical officers (5.8 to 6.8) but remain low for refractionists (including optometrists, at 3.6 in 2011 and 2020). Among countries that have not already achieved target indicators, however, practitioner growth will be insufficient for any additional countries to reach the surgeon and refractionist targets by year 2020. Without further strategy change and investment, even after 2020, surgeon growth is only expected to sufficiently outpace general population growth to reach the target in one country. For nurses, two additional countries will achieve the target while one will fall below it. In 2011, high surgeon practitioner ratios were associated with high CSR, regardless of the type of surgeon employed. The cataract surgeon workforce is growing proportionately faster than the ophthalmologist. Conclusions The HReH workforce is not growing fast enough to achieve global eye health targets in most of the sub-Saharan countries we surveyed by 2020. Countries seeking to make rapid progress to improve CSR could prioritise investment in training new cataract surgeons over ophthalmologists and improving surgical output efficiency.
- Published
- 2014
126. Modelo formativo de múltiples entradas y salidas en Salud Visual
- Author
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Universitat Politècnica de Catalunya. Institut de Ciències de l'Educació, Guisasola València, Laura, Rius, Anna, Kovin, Naidoo, Universitat Politècnica de Catalunya. Institut de Ciències de l'Educació, Guisasola València, Laura, Rius, Anna, and Kovin, Naidoo
- Abstract
Es por todos aceptado, que los modelos formativos a seguir son aquellos que siguen los patrones de los países más desarrollados. Estos modelos formativos basan su éxito en formar cualificados estudiantes que adquieren niveles elevados de conocimiento que les permitirá dar respuesta a avanzados problemas. Sin embargo este tipo de modelos formativos no siempre soluciona los problemas reales en países con niveles inferiores de desarrollo. El modelo formativo que recoge este CD adecua los sistemas formativos a las necesidades reales de cada sociedad, y en concreto en las áreas geográficas donde los niveles de pobreza exigen respuestas a corto plazo. Es el caso concreto de la Salud, y mas específicamente en la Salud Visual, el Modelo de múltiples entradas y salidas en Salud Visual, permite formar profesionales capaces de ofrecer un servicio de atención primaria básica, en países donde las condiciones de vida y la pobreza dificultan el acceso a la educación y a la sanidad. Un equipo de 14 profesores de las Universidades Politécnica de Catalunya (Barcelona España) y Kwa-Zulu Natal (Durban Sudáfrica) se ha encargado de elaborar sus contenidos. Estos profesores son expertos en cada una de las temáticas que recoge el CD.
- Published
- 2007
127. Disability weights for vision disorders in Global Burden of Disease study
- Author
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Jill E Keeffe, Janet L Leasher, Serge Resnikoff, Hugh R. Taylor, Kovin Naidoo, Jost B. Jonas, and Konrad Pesudovs
- Subjects
Burden of disease ,medicine.medical_specialty ,business.industry ,MEDLINE ,Physical therapy ,medicine ,General Medicine ,Intensive care medicine ,business - Published
- 2013
128. Prevalence and Correction of Near Vision Impairment at Seven Sites in China, India, Nepal, Niger, South Africa, and the United States
- Author
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Kovin Naidoo, Leon B. Ellwein, Mingguang He, Yuddha Dhoj Sapkota, Jialiang Zhao, Amza Abdou, Ravilla D. Thulasiraj, and Rohit Varma
- Subjects
Adult ,Male ,Rural Population ,China ,Refractive error ,Visual acuity ,Urban Population ,genetic structures ,Cross-sectional study ,Visual Acuity ,India ,Vision, Low ,South Africa ,Near vision ,Nepal ,Ethnicity ,Myopia ,Prevalence ,medicine ,Humans ,Niger ,Aged ,Aged, 80 and over ,Vision, Binocular ,Odds ratio ,Presbyopia ,Middle Aged ,medicine.disease ,United States ,Ophthalmology ,Cross-Sectional Studies ,Eyeglasses ,Geography ,Optometry ,Female ,Cluster sampling ,medicine.symptom ,Visually Impaired Persons ,Demography - Abstract
Purpose To estimate the prevalence of near vision impairment and use of corrective spectacles among middle-aged and older adults in different settings and ethnic groups. Design Population-based, cross-sectional study. Methods People aged ≥35 years were randomly selected with cluster sampling in 4 rural settings in Shunyi (China), Kaski (Nepal), Madurai (India), and Dosso (Niger); 1 semi-urban area in Durban (South Africa); and 2 urban settings in Guangzhou (China) and Los Angeles (USA). Near visual acuity (VA), with and without presenting near correction, was measured at 40 cm using a logMAR near vision tumbling E chart. Subjects with uncorrected binocular near VA ≤20/40 were tested with plus spheres to obtain the best-corrected binocular VA. Results A total of 17 734 persons aged ≥35 years were enumerated and 14 805 (83.5%) were examined. The age- and sex-standardized prevalence of uncorrected near vision impairment (VA ≤20/40) ranged from 49% in Dosso to 60% in Shunyi and Guangzhou, 65% in Kaski and Los Angeles, and 83% in Madurai and Durban. The prevalence of near vision impairment based on best-corrected visual acuity was less than 10% in Guangzhou, Kaski, Durban, and Los Angeles, but as high as 23% in Madurai. In multiple logistic regression models, uncorrected near vision impairment was associated with older age (odds ratio [OR] = 1.14, P P = .027), but not with educational level (OR = 1.01, P = .812). Over 90% of people in need of near refractive correction in rural settings did not have the necessary spectacles. These rates were 40% in urban settings. Conclusions By 50 years of age, the majority of people suffer from near vision impairment, most of which can be corrected optically. Over 90% of those in need of near refractive correction in rural settings do not have the necessary spectacles.
- Published
- 2012
129. Global Vision Impairment Due to Uncorrected Presbyopia
- Author
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Reg Wong, Kovin Naidoo, Anthea Burnett, S. May Ho, Sonja Cronjé, Brien A. Holden, Gerhard Schlenther, Kevin D. Frick, Eric B. Papas, and Timothy R. Fricke
- Subjects
Adult ,Refractive error ,Databases, Factual ,genetic structures ,Referral ,Population ,Visual impairment ,Vision Disorders ,Global Health ,Diabetic Eye Disease ,Vision disorder ,Cost of Illness ,Prevalence ,Global health ,medicine ,Humans ,education ,Aged ,education.field_of_study ,business.industry ,Presbyopia ,Middle Aged ,medicine.disease ,Ophthalmology ,Eyeglasses ,Optometry ,medicine.symptom ,business ,Visually Impaired Persons - Abstract
Objectives To evaluate the personal and community burdens of uncorrected presbyopia. Methods We used multiple population-based surveys to estimate the global presbyopia prevalence, the spectacle coverage rate for presbyopia, and the community perception of vision impairment caused by uncorrected presbyopia. For planning purposes, the data were extrapolated for the future using population projections extracted from the International Data Base of the US Census Bureau. Results It is estimated that there were 1.04 billion people globally with presbyopia in 2005, 517 million of whom had no spectacles or inadequate spectacles. Of these, 410 million were prevented from performing near tasks in the way they required. Vision impairment from uncorrected presbyopia predominantly exists (94%) in the developing world. Conclusions Uncorrected presbyopia causes widespread, avoidable vision impairment throughout the world. Alleviation of this problem requires a substantial increase in the number of personnel trained to deliver appropriate eye care together with the establishment of sustainable, affordable spectacle delivery systems in developing countries. In addition, given that people with presbyopia are at higher risk for permanently sight-threatening conditions such as glaucoma and diabetic eye disease, primary eye care should include refraction services as well as detection and appropriate referral for these and other such conditions.
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- 2008
130. Refractive Error and Visual Impairment in African Children in South Africa
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Gopal P. Pokharel, Pirindhavellie Govender, Khathutshelo P. Mashige, Leon B. Ellwein, Avesh Raghunandan, Kovin Naidoo, and Brien A. Holden
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Male ,Rural Population ,medicine.medical_specialty ,Refractive error ,Visual acuity ,Adolescent ,Urban Population ,genetic structures ,Eye disease ,Visual impairment ,Vision Disorders ,Visual Acuity ,Black People ,Vision disorder ,Random Allocation ,South Africa ,Ophthalmology ,Prevalence ,medicine ,Humans ,Vision test ,Child ,Retinoscopy ,medicine.diagnostic_test ,business.industry ,Vision Tests ,Cycloplegia ,Refractive Errors ,medicine.disease ,eye diseases ,Child, Preschool ,Optometry ,Female ,medicine.symptom ,business - Abstract
Purpose To assess the prevalence of refractive error and visual impairment in school-aged African children in South Africa. Methods Random selection of geographically defined clusters was used to identify a sample of children 5 to 15 years of age in the Durban area. From January to August 2002, children in 35 clusters were enumerated through a door-to-door survey and examined in temporary facilities. The examination included visual acuity measurements, ocular motility evaluation, retinoscopy and autorefraction under cycloplegia, and examination of the anterior segment, media, and fundus. In nine clusters, children with reduced vision and a sample of those with normal vision underwent independent replicate examinations for quality assurance. Results A total of 5599 children living in 2712 households were enumerated, and 4890 (87.3%) were examined. The prevalence of uncorrected, presenting, and best-corrected visual acuity of 20/40 or worse in the better eye was 1.4%, 1.2%, and 0.32%, respectively. Refractive error was the cause in 63.6% of the 191 eyes with reduced vision, amblyopia in 7.3%, retinal disorders in 9.9%, corneal opacity in 3.7%, other causes in 3.1%, and unexplained causes in the remaining 12.0%. Exterior and anterior segment abnormalities were observed in 528 (10.8%) children, mainly corneal and conjunctival. Myopia (at least -0.50 D) in one or both eyes was present in 2.9% of children when measured with retinoscopy and in 4.0% measured with autorefraction. Beginning with an upward trend at age 14, myopia prevalence with autorefraction reached 9.6% at age 15. Myopia was also associated with increased parental education. Hyperopia (+2.00 D or more) in at least one eye was present in 1.8% of children when measured with retinoscopy and in 2.6% measured with autorefraction, with no significant predictors of hyperopia risk. Conclusions The prevalence of reduced vision is low in school-age African children, most of it because of uncorrected refractive error. The high prevalence of corneal and other anterior segment abnormalities is a reflection of the inadequacy of primary eye care services in this area.
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- 2003
131. PRIMARY EYECARE EDUCATION IN THE DEVELOPING COUNTRIES OF AFRICA
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Timothy R. Fricke, Brien A. Holden, Kovin Naidoo, and Sonja Cronjé
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Ophthalmology ,Economic growth ,Political science ,Optometry ,Developing country - Published
- 2002
132. DEVELOPING SUSTAINABLE EYECARE FOR THE PALESTINIAN PEOPLE: A PARTNERSHIP PROGRAM
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Kovin Naidoo and Kherieh Kharouf
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Ophthalmology ,Economic growth ,business.industry ,General partnership ,Environmental resource management ,business ,Optometry - Published
- 2001
133. OPTOMETRY IN TANZANIA: A 10 YEAR PLAN
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Brien A. Holden, Julius Kamugisha, Kovin Naidoo, Yvette Waddell, and Sonja Cronjé
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Ophthalmology ,Tanzania ,biology ,business.industry ,Plan (archaeology) ,Optometry ,Medicine ,biology.organism_classification ,business - Published
- 2001
134. The Global Burden of Potential Productivity Loss from Uncorrected Presbyopia
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Kevin D. Frick, David A. Wilson, Kovin Naidoo, Brien A. Holden, and Susan M. Joy
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Adult ,Male ,medicine.medical_specialty ,genetic structures ,Gross Domestic Product ,Population ,Vision Disorders ,Efficiency ,Audiology ,Global Health ,World Health Organization ,Gross domestic product ,Near vision ,Cost of Illness ,Global health ,Per capita ,medicine ,Prevalence ,Humans ,Age of Onset ,education ,Productivity ,Aged ,education.field_of_study ,business.industry ,Presbyopia ,Middle Aged ,medicine.disease ,Ophthalmology ,Unemployment ,Population data ,Female ,business ,Visually Impaired Persons ,Demography - Abstract
PurposeThe onset of presbyopia in middle adulthood results in potential losses in productivity among otherwise healthy adults if uncorrected or undercorrected. The economic burden could be significant in lower-income countries, where up to 94% of cases may be uncorrected or undercorrected. This study estimates the global burden of potential productivity lost because of uncorrected functional presbyopia.DesignPopulation data from the US Census Bureau were combined with the estimated presbyopia prevalence, age of onset, employment rate, gross domestic product (GDP) per capita in current US dollars, and near vision impairment disability weights from the Global Burden of Disease 2010 study to estimate the global loss of productivity from uncorrected and undercorrected presbyopia in each country in 2011. To allow comparison with earlier work, we also calculated the loss with the conservative assumption that the contribution to productivity extends only up to 50 years of age.ParticipantsThe economic modeling did not require the use of subjects.MethodsWe estimated the number of cases of uncorrected or undercorrected presbyopia in each country among the working-age population. The number of working-age cases was multiplied by the labor force participation rate, the employment rate, a disability weight, and the GDP per capita to estimate the potential loss of GDP due to presbyopia.Main Outcome MeasuresThe outcome being measured is the lost productivity in 2011 US dollars resulting from uncorrected or undercorrected presbyopia.ResultsThere were an estimated 1.272 billion cases of presbyopia worldwide in 2011. A total of 244 million cases, uncorrected or undercorrected among people aged
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135. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050
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Brien A. Holden, David A. Wilson, Kovin Naidoo, Tien Yin Wong, Monica Jong, Serge Resnikoff, Thomas Naduvilath, Timothy R. Fricke, and Padmaja Sankaridurg
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0301 basic medicine ,education.field_of_study ,business.industry ,medicine.medical_treatment ,Visual impairment ,Population ,Orthokeratology ,World population ,Confidence interval ,03 medical and health sciences ,Ophthalmology ,030104 developmental biology ,0302 clinical medicine ,Meta-analysis ,Urbanization ,030221 ophthalmology & optometry ,medicine ,Global health ,Optometry ,medicine.symptom ,education ,business ,Demography - Abstract
Purpose Myopia is a common cause of vision loss, with uncorrected myopia the leading cause of distance vision impairment globally. Individual studies show variations in the prevalence of myopia and high myopia between regions and ethnic groups, and there continues to be uncertainty regarding increasing prevalence of myopia. Design Systematic review and meta-analysis. Methods We performed a systematic review and meta-analysis of the prevalence of myopia and high myopia and estimated temporal trends from 2000 to 2050 using data published since 1995. The primary data were gathered into 5-year age groups from 0 to ≥100, in urban or rural populations in each country, standardized to definitions of myopia of −0.50 diopter (D) or less and of high myopia of −5.00 D or less, projected to the year 2010, then meta-analyzed within Global Burden of Disease (GBD) regions. Any urban or rural age group that lacked data in a GBD region took data from the most similar region. The prevalence data were combined with urbanization data and population data from United Nations Population Department (UNPD) to estimate the prevalence of myopia and high myopia in each country of the world. These estimates were combined with myopia change estimates over time derived from regression analysis of published evidence to project to each decade from 2000 through 2050. Results We included data from 145 studies covering 2.1 million participants. We estimated 1406 million people with myopia (22.9% of the world population; 95% confidence interval [CI], 932–1932 million [15.2%–31.5%]) and 163 million people with high myopia (2.7% of the world population; 95% CI, 86–387 million [1.4%–6.3%]) in 2000. We predict by 2050 there will be 4758 million people with myopia (49.8% of the world population; 3620–6056 million [95% CI, 43.4%–55.7%]) and 938 million people with high myopia (9.8% of the world population; 479–2104 million [95% CI, 5.7%–19.4%]). Conclusions Myopia and high myopia estimates from 2000 to 2050 suggest significant increases in prevalences globally, with implications for planning services, including managing and preventing myopia-related ocular complications and vision loss among almost 1 billion people with high myopia.
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136. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
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Audrey Bonaventure, Sumeet S. Chugh, Roderick J. Hay, Luigi Naldi, Derrick A Bennett, Bridget F. Grant, Tony R. Merriman, Goodarz Danaei, Francine Laden, Rupak Shivakoti, Steven D. Colan, Kovin Naidoo, Kyle J Foreman, David A. Sleet, Aref A. Bin Abdulhak, Christopher J L Murray, Marita Cross, S. Ali, Karen Courville De Vaccaro, Richard F. Gillum, Herbert C. Duber, R Gupta, Carol Brayne, Fernando Perez-Ruiz, David Gunnell, Janet L Leasher, Dharani Ranganathan, James Leigh, Maria Loane, Kathryn G. Andrews, Steven T. Wiersma, Mengru Wang, Ella Sanman, Andrea Panozo Rivero, Robert G. Weintraub, Giorgio Tamburlini, F.G.R. Fowkes, Mohammad H. Forouzanfar, Safa Abdalla, Michael Phillips, Jürgen Rehm, Hannah Blencowe, George A. Mensah, Jeffrey A. Towbin, James D. Wilkinson, Pon Hsiu Yeh, Hammad A. Ganatra, Soufiane Boufous, Adrian Davis, Myles Connor, Simon Brooker, Bruno Hoen, Josep Maria Haro, Seth Flaxman, Ziad A. Memish, Eduardo A. Undurraga, Patricia Espindola, Laurie M. Anderson, Sarah Derrett, Esteban Porrini, Don C. Des Jarlais, Samath D Dharmaratne, Steven E. Lipshultz, Robert P. Dellavalle, Spencer L. James, Cleusa P. Ferri, Kerrianne Watt, Mohammad A. AlMazroa, Emma Smith, Suzanne Barker-Collo, Wei Liu, Mariel M. Finucane, Rupert R A Bourne, Uchechukwu Sampson, Valeria Miglioli, Summer Lockett Ohno, Michael C. Nevitt, Michael K Mwaniki, Kaustubh Dabhadkar, Harvey Whiteford, David Singh, Doruk Ozgediz, Luca Ronfani, Peter Burney, Juanita A. Haagsma, Holly Hagan, Loreto Carmona, Ali A. Mokdad, Bishnu Pahari, Patricia J. Erwin, Jonathan R. Carapetis, Kathryn H. Jacobsen, Imad M. Tleyjeh, Bishal Bhandari, Emmanuela Gakidou, John J Huang, Paul K. Nelson, Lisa C. Rosenfeld, David Phillips, Michael S Lipnick, Louise Flood, Lidia Sanchez-Riera, John R. Condon, Robin Marks, Jasvinder A. Singh, Charles R. Newton, Adofo Koranteng, Hugh R. Taylor, Nicholas J Kassebaum, Nicole E. Johns, Elizabeth S Limb, Roy Burstein, Christine M. Budke, Amanda J Baxter, Tim Driscoll, Lesley Rushton, Casey Olives, Andrew E. Moran, Richard A. Gosselin, Maziar Moradi-Lakeh, Theo Vos, Jacqueline Mabweijano, James Scott, Ganesan Karthikeyan, Rogelio Perez Padilla, Neil McGill, Beth E. Ebel, John K Lin, Marc G. Weisskopf, Jeyaraj D Pandian, Ratilal Lalloo, Matthew J. Miller, Hélène Carabin, Allyne Delossantos, Leslie T. Cooper, Sandra Nolte, Andrew C Steer, Daphna Levinson, Nabila Dahodwala, G. Remuzzi, Christopher Hill, Ted R. Miller, Diana Haring, Andre Keren, Holly E. Erskine, Hwashin Shin, Sukanta Saha, Louisa Degenhardt, Ralph L. Sacco, Leslie Mallinger, Guilherme V. Polanczyk, Felipe Rodriguez De Leòn, Maria Segui-Gomez, Reza Malekzadeh, Akira Matsumori, James Harrison, Honglei Chen, Luc E. Coffeng, Joshua A. Salomon, David Chou, Wagner Marcenes, Clotilde Ubeda, Helen Dolk, Sean R.M. Williams, Jerry Abraham, Sana Syed, William G. Couser, Lope H Barrero, K. Ellicott Colson, Wenzhi Wang, Ian Bolliger, Homie Razavi, Laura L Laslett, William J. Taylor, Anita K. M. Zaidi, Guy B. Marks, María-Gloria Basáñez, Claudia Cella, Miriam Alvarado, Saeid Shahraz, John J. McGrath, David J. Margolis, Neil Pearce, Charles Mock, Yara A. Halasa, Robin Room, David J. Weatherall, Kathryn Richardson, Karen Sliwa, Rafael Lozano, Diego De Leo, Zhi Jie Zheng, Peter Brooks, Thomas Roberts, Anthony D. Woolf, Paul Norman, Lorenzo Monasta, Majid Ezzati, Mohammed K. Ali, Frederick P. Rivara, Timothy J. Steiner, María Elena Medina-Mora, Kavi Bhalla, Victor Aboyans, Mathilda Regan, Stalin E. Ewoigbokhan, Michele Meltzer, Damian G Hoy, Charles E. Canter, Belinda J. Gabbe, Matthew A. Corriere, Sébastien D. S. Pion, Gretchen L. Birbeck, Geoffrey Buckle, Stephanie Y. Ahn, Martin A. Weinstock, Ronan A Lyons, Karen Edmond, Terrie E. Moffitt, Farshad Farzadfar, Norito Kawakami, W. Murray Thomson, Abraham D. Flaxman, Boris Bikbov, Jessica Singleton, Rachel L. Pullan, Simon J. O’Hanlon, Howard J. Hoffman, Svetlana Popova, Charles Atkinson, Saad B. Omer, Sherine E. Gabriel, Jim van Os, David T. Felson, Bianca Garcia, Wayne Hall, Sydney E. Ibeanusi, Philip B. Mitchell, Chiara Bucello, Michelle L. Bell, Flavio Gaspari, Donald H. Silberberg, Alexis Elbaz, Monica S. Vavilala, Tim Lathlean, Samantha M. Colquhoun, Kelsey Pierce, Larry M. Baddour, Michael H. Criqui, Ana Olga Mocumbi, Francis Guillemin, Farshad Pourmalek, Robert G. Nelson, Mary M. McDermott, M. Nathan Nair, Justina Groeger, Manu Dahiya, Rebecca Grainger, Yong Yi Lee, Emma Witt, Kenji Shibuya, Eduardo Bernabé, Alize J. Ferrari, George D. Thurston, Rakesh Aggarwal, David C. Schwebel, Gerhard Gmel, Jost B. Jonas, Hideki Higashi, Andrew Page, Peter J. Hotez, Hywel C Williams, Michael Freeman, Marcello Tonelli, Bernadette Thomas, Richard H. Osborne, David B. Rein, Lisa Bridgett, Jed D. Blore, Olive Kobusingye, Mukesh Dherani, Rita Krishnamurthi, Lisa M. Knowlton, Miltiadis K. Tsilimbaris, Rintaro Mori, E. Ray Dorsey, Katrina F Ortblad, Deborah Jarvis, Martin O'Donnell, Jon Paul Khoo, Valery L. Feigin, Ana-Claire Meyer, Kapa D. Ramaiah, Wilma A. Stolk, Michele E. Murdoch, Bianca Calabria, Cesar Diaz-Torne, James A. Black, Michael F. MacIntyre, Rachelle Buchbinder, C. Arden Pope, Donald S. Shepard, Monica Cortinovis, Richard Matzopoulos, Frederick Wolfe, Lidia Morawska, Narayanaswamy Venketasubramanian, Stephen S Lim, Diego Gonzalez-Medina, Traolach S. Brugha, Sivabalan Manivannan, Benjamin C Cowie, David Zonies, Emelia J. Benjamin, Sudha Jayaraman, Catherine Michaud, Gitanjali M Singh, Alan D. Lopez, K.M. Venkat Narayan, Fiona M. Blyth, Mohammad Tavakkoli, Benjamin L. Campbell, Carolyn Robinson, Suzanne Polinder, Marlene Fransen, Thomas Truelsen, Rasmus Havmoeller, Bongani M. Mayosi, Konrad Pesudovs, Myrna M. Weissman, Tasanee Braithwaite, Claire Bryan-Hancock, James Damsere-Derry, Richard A. White, John H. McAnulty, Natasha Wiebe, Fiona J Charlson, Norberto Perico, Charles H. King, Lyn March, Andrew T. A. Cheng, Ilana N. Ackerman, Rosana E. Norman, Jennifer L. Smith, Michael Burch, Adil N. Bahalim, Eric M. Fèvre, H. Ross Anderson, Julie O. Denenberg, Nicolas J. C. Stapelberg, David Bartels, Michel Boussinesq, Marieke J. van der Werf, Scott B. Patten, Marcella Montico, Rashmi Jasrasaria, Sarah Wulf, Lars Jacob Stovner, Mohsen Naghavi, Jennifer A. Taylor, Martin Prince, Christopher R. Sudfeld, Neuroépidémiologie Tropicale ( NET ), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Institut Génomique, Environnement, Immunité, Santé, Thérapeutique ( GEIST ), Université de Limoges ( UNILIM ) -Université de Limoges ( UNILIM ), Service de Chirurgie Thoracique et Vasculaire - Médecine vasculaire [CHU Limoges], CHU Limoges, Bioinformatics, GlaxoSmithKline, Institut Jacques Monod ( IJM ), Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), Institute of Parasitology, Respiratory Epidemiology and Public Health, Imperial College London-Royal Brompton Hospital-National Heart and Lung Institute, EUROCAT Central Registry, Institute for Nursing Research-University of Ulster, Neuroépidémiologie, Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Centre d'Epidémiologie Clinique ( CIC-EC ), Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), University of Bristol [Bristol], Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Service des maladies infectieuses et tropicales, Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Hôpital Saint-Jacques, Respiratory Epidemiology and Public Health Group, Imperial College London-National Heart and Lung Institute, Research & Planning, Mental Health Services, Ministry of Health, Tehran University of Medical Sciences, Anaesthetics, Southampton University Hospital, Cisco Systems, CISCO Systems, Inc, Department of dermatology, Milano University-Azienda Ospedaleria Ospedali Riuniti di Bergamo, Massey University Wellington Campus, centre for photomolecular science, Imperial College London, Department of Radiology, Weill Medical College of Cornell University [New York], Department of neurology, Miller School of Medicine-University of Miami [Coral Gables], Department of Pediatrics, Institute of Child Health, IRCCS Burlo Garofolo, Département Cité des métiers - Cité de la santé - Universcience ( CDM/CDS ), Cité des Sciences et de l'Industrie, The Weatherall Institute of Molecular Medicine, University of Oxford [Oxford], Neuroépidémiologie Tropicale (NET), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Imperial College London-Royal Brompton Hospital-National Heart and Lung Institute [UK], Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Epidémiologie Clinique (CIC-EC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Hôpital Saint-Jacques, Imperial College London-National Heart and Lung Institute [UK], Ministry of Health [Mozambique], Massey University, University of Miami [Coral Gables]-University of Miami Leonard M. Miller School of Medicine (UMMSM), Département Cité des métiers - Cité de la santé - Universcience (CDM/CDS), Psychiatrie & Neuropsychologie, RS: MHeNs School for Mental Health and Neuroscience, Centre d'investigation clinique - Epidémiologie clinique [Nancy] (CIC-EC), Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Hôpital Saint-Jacques, Laboratoire Chrono-environnement (UMR 6249) (LCE), University of Miami Leonard M. Miller School of Medicine (UMMSM)-University of Miami [Coral Gables], University of Oxford, Cardiothoracic Surgery, Public Health, Immunology, and Cell biology
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Gerontology ,Male ,MESH : Prevalence ,Health Status ,MESH : Aged ,Poison control ,Public-health utility ,MESH : Child, Preschool ,Global Health ,0302 clinical medicine ,MESH: Aged, 80 and over ,MESH : Child ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,MESH: Child ,Prevalence ,MESH : Female ,030212 general & internal medicine ,Child ,MESH: Health Status ,MESH: Aged ,Aged, 80 and over ,education.field_of_study ,Communicable disease ,MESH: Middle Aged ,MESH: Infant, Newborn ,1. No poverty ,Age Factors ,MESH : Infant ,General Medicine ,Middle Aged ,MESH : Adult ,MESH: Infant ,Countries ,3. Good health ,MESH : Wounds and Injuries ,Risk-factors ,MESH: Quality-Adjusted Life Years ,MESH : World Health ,[ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,MESH: Young Adult ,Child, Preschool ,Female ,Quality-Adjusted Life Years ,Lost ,Adult ,Adolescent ,MESH : Male ,MESH : Sex Factors ,Population ,MESH : Young Adult ,MESH : Infant, Newborn ,03 medical and health sciences ,Expectancy ,Young Adult ,Sex Factors ,MESH: Sex Factors ,SDG 3 - Good Health and Well-being ,MESH : Adolescent ,medicine ,Disability-adjusted life year ,Humans ,Economic cost ,MESH : Middle Aged ,Mortality ,MESH : Health Status ,education ,MESH : Aged, 80 and over ,Disease burden ,MESH: Prevalence ,Aged ,MESH: Adolescent ,MESH: Age Factors ,MESH: Humans ,business.industry ,MESH: Child, Preschool ,MESH : Humans ,Australia ,Infant, Newborn ,Infant ,MESH: Adult ,MESH : Quality-Adjusted Life Years ,Non-communicable disease ,medicine.disease ,MESH: Male ,Quality-adjusted life year ,Years of potential life lost ,MESH: Wounds and Injuries ,Wounds and Injuries ,MESH : Age Factors ,Copd ,business ,MESH: Female ,030217 neurology & neurosurgery ,MESH: World Health ,Demography - Abstract
International audience; BACKGROUND: Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of ill-health. The 1990 Global Burden of Disease study proposed disability-adjusted life years (DALYs) to measure disease burden. No comprehensive update of disease burden worldwide incorporating a systematic reassessment of disease and injury-specific epidemiology has been done since the 1990 study. We aimed to calculate disease burden worldwide and for 21 regions for 1990, 2005, and 2010 with methods to enable meaningful comparisons over time. METHODS: We calculated DALYs as the sum of years of life lost (YLLs) and years lived with disability (YLDs). DALYs were calculated for 291 causes, 20 age groups, both sexes, and for 187 countries, and aggregated to regional and global estimates of disease burden for three points in time with strictly comparable definitions and methods. YLLs were calculated from age-sex-country-time-specific estimates of mortality by cause, with death by standardised lost life expectancy at each age. YLDs were calculated as prevalence of 1160 disabling sequelae, by age, sex, and cause, and weighted by new disability weights for each health state. Neither YLLs nor YLDs were age-weighted or discounted. Uncertainty around cause-specific DALYs was calculated incorporating uncertainty in levels of all-cause mortality, cause-specific mortality, prevalence, and disability weights. FINDINGS: Global DALYs remained stable from 1990 (2*503 billion) to 2010 (2*490 billion). Crude DALYs per 1000 decreased by 23% (472 per 1000 to 361 per 1000). An important shift has occurred in DALY composition with the contribution of deaths and disability among children (younger than 5 years of age) declining from 41% of global DALYs in 1990 to 25% in 2010. YLLs typically account for about half of disease burden in more developed regions (high-income Asia Pacific, western Europe, high-income North America, and Australasia), rising to over 80% of DALYs in sub-Saharan Africa. In 1990, 47% of DALYs worldwide were from communicable, maternal, neonatal, and nutritional disorders, 43% from non-communicable diseases, and 10% from injuries. By 2010, this had shifted to 35%, 54%, and 11%, respectively. Ischaemic heart disease was the leading cause of DALYs worldwide in 2010 (up from fourth rank in 1990, increasing by 29%), followed by lower respiratory infections (top rank in 1990; 44% decline in DALYs), stroke (fifth in 1990; 19% increase), diarrhoeal diseases (second in 1990; 51% decrease), and HIV/AIDS (33rd in 1990; 351% increase). Major depressive disorder increased from 15th to 11th rank (37% increase) and road injury from 12th to 10th rank (34% increase). Substantial heterogeneity exists in rankings of leading causes of disease burden among regions. INTERPRETATION: Global disease burden has continued to shift away from communicable to non-communicable diseases and from premature death to years lived with disability. In sub-Saharan Africa, however, many communicable, maternal, neonatal, and nutritional disorders remain the dominant causes of disease burden. The rising burden from mental and behavioural disorders, musculoskeletal disorders, and diabetes will impose new challenges on health systems. Regional heterogeneity highlights the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account. Because of improved definitions, methods, and data, these results for 1990 and 2010 supersede all previously published Global Burden of Disease results. FUNDING: Bill & Melinda Gates Foundation.
137. Visual profile of students in integrated schools in Malawi
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Dinesh Kaphle, Sanjay Marasini, Angela Reading, Kovin Naidoo, and Khumbo Kalua
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Adult ,Male ,genetic structures ,Blindness ,Adolescent ,business.industry ,Visual impairment ,Vision Disorders ,Visual Acuity ,medicine.disease ,eye diseases ,Low vision ,Ophthalmology ,Child, Preschool ,medicine ,Optometry ,Humans ,Female ,medicine.symptom ,business ,Child ,Students - Abstract
Blindness and visual impairment are very common in African countries and are often loosely linked to inadequate resources. We designed this study to assess clinical visual and ocular characteristics of children in three integrated schools in Malawi, so that students needing low vision services or those with correctable refractive error will be identified.We included 95 students, who underwent a detailed optometric examination. The assessment included distance visual acuity measurement in logMAR notation, near visual acuity, oculo-motor assessment, pupillary assessment and anterior as well as posterior segment evaluation. Non-cycloplegic refraction was done in all the participants.Mean age of students was 13.84 ±4.61 years. Almost 90 per cent of students had presenting visual acuity worse than logMAR 0.54. Visual acuity improved significantly after refractive correction by more than two logMAR lines in 31.8 per cent (p0.0001). Refractive error was very common (36.5 per cent) and the most common causes of visual impairment were lenticular (21.2 per cent), corneal (20.0 per cent) and albinism (15.3 per cent). One-tenth (10.5 per cent) of the students were wrongly enrolled in the schools, even though they did not have visual impairment. The compliance to spectacles wear was very poor (37 per cent). An adequate refractive correction improved visual acuity in more than a third (36.5 per cent) of the students. Students benefited from spectacle magnifiers (18.8 per cent), handheld magnifiers (4.7 per cent) and telescopes (5.9 per cent). Mobility canes were advised for 36.5 per cent of the students.Nine out of ten students in three integrated schools in Malawi had visual impairment and 41 per cent had low vision. Inappropriate placement in the integrated schools and poor spectacle compliance are very common. Well accepted optical and non-optical devices could improve visual performance in visually disabled children, for which public awareness and parental education is important.
138. An Economic Analysis of the Impact of Refractive Error in Mozambique
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Thompson, Stephen, Geoff Harris, Kovin Naidoo and James Loughman, and Mozambique Eyecare Project
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refractive error ,Mozambique ,economic analysis ,Optometry - Abstract
Mozambique eyecare project carried out in June 2013 to estimate the socio-economic benefit of an Optometry Programme by calculating the benefits of addressing refractive error in terms of productivity gained as a result of the intervention.
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- 2013
139. Addressing Uncorrected Refractive Error Through Human Resource Development in the Context of Mozambique
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Thompson, Stephen, Loughman, James, Ramson, Prasidh, Bilotto, Luigi, Naidoo, Kovin, Dr. James Loughman, Prof. Kovin Naidoo, Prof. Geoff Harris, and Irish Aid / Technological University Dublin
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genetic structures ,Health ,Human resources ,education ,eye diseases ,Mozambique ,Optometry - Abstract
This paper presents results from a national situational analysis. An International Agency for Prevention of Blindness (IAPB) tool was used to map current eye care services recorded including human resource and equipment. Data was analysed against VISION 2020 Human Resource targets.
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- 2012
- Full Text
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140. One Student One Family and the Mozambique Eyecare Project
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Thompson, Stephen, Phelan, Aoife, Santana, Tatiana, Catarino, Elizebete, Ocampo, Vivien, Cesar Faria, Cesar Faria, Lougman, James, Dr. James Loughman, Prof. Kovin Naidoo, Prof. Geoff Harris, and Irish Aid / Technological University Dublin
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Community project ,Eyecare ,Ophthalmology ,Eye Diseases ,Higher education ,Health Services Research ,Mozambique - Abstract
Background - The Mozambique Eyecare Programme is funded by Irish Aid and designed to address the need for optometric education in Lusophone Africa. It is a multi-partner collaboration between Universidade Lúrio, Mozambique, Technological University Dublin, Ireland, University of Ulster, Northern Ireland, and The International Centre for Eyecare Education (ICEE) an international Non Government Organisation. A key output from the programme is the development of an optometry school based at Universidade Lúrio, the first of its kind in Mozambique. The aim is to address unmet eye care needs through human resource development. All students enrolled at Universidade Lúrio, including the optometry students, are required to participate in the One Student One Family programme. This initiative aims to improve the public health of disadvantaged communities in Nampula province through information dissemination and increased interaction between health science students and the general public. It also provides the students with the opportunity to interact with the community and apply their theoretical knowledge in the local context. This experience will enhance their patient care and as it is a community informed project, it ensures the wider eyecare programme follows a pro-poor approach. Aim - This paper aims to analyse the lessons learnt from the programme so far. Methods - Surveys and key informant interviews with optometry students, individuals within communities, teaching faculty and partners involved with the Mozambique Eyecare Project will form the basis of the analysis. Results - The results are expected to indicate both the successes and failures of the One Student One Family programme. The results will contribute to the development of a framework to improve the programme in order to achieve the desired outcome of improved community eye health. Conclusion - The Mozambique Eyecare Project is developing human resources in Lusophone Africa through a partnership linking higher education institutions in Europe and Africa. The One Student One Family programme addresses a current deficit in eyecare knowledge within the local community by transferring knowledge from optometry students to the general public. In conclusion, innovative models of education and interaction between students and the community is necessary to address the eye care needs of the country, the region and the continent.
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- 2011
141. Addressing the Burden of Uncorrected Refractive Error in Mozambique
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Thompson, Stephen, Loughman, James, Prasidh Ramson, Prasidh Ramson, Bilotti, Luigi, Harris, Geoff, Naidoo, Kovin, Dr. James Loughman, Prof. Kovin Naidoo, Prof. Geoff Harris, and Irish Aid / Technological University Dublin
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Uncorrected Refractive Error ,Eye Diseases ,Community Health and Preventive Medicine ,Health Services Research ,Visual impairment ,Blindness ,Mozambique ,Optometry - Abstract
A situational analysis indicates a lack of eye health personnel who can and do refract. The logical course of action would be to train more eye health personnel. A conservative estimated annual burden of URE in lost productivity in Mozambique is $14,486,692. To achieve the V2020 target ratio, an extra 184 workers are needed in six provinces analysed.The analysis assumes the existing personnel are well trained and dedicate time to offering a refraction service. It also assumes that the patient receives the care they require. Other aspects of the situational analysis suggest this is currently not always the case. A more comprehensive analysis would look at the number of work hours each person dedicates to refraction and the outcome.
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- 2011
142. The Mozambique Eyecare Project: Implementing a Model That Addresses Uncorrected Refractive Error in Lusophone Africa
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Thompson, Stephen, Wallace, Diane, Dr. James Loughman, Prof. Kovin Naidoo, Prof. Geoff Harris, and Irish Aid / Technological University Dublin
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Eyecare ,Ophthalmology ,Eye Diseases ,Lusophone ,Mozambique - Abstract
BACKGROUND Optometric education and resources are drastically deficient in most of Africa, more so in Lusophone Africa where the problem is compounded by language barriers which isolate these countries from related developments in Africa and/or the developed world. The Mozambique Eyecare Programme is a multi-partner collaboration between The International Centre for Eyecare Education (ICEE), Universidade Lúrio in Mozambique, Technological University Dublin, and the University of Ulster in Ireland, designed to address the need for optometric education in Lusophone Africa. AIM This paper aims to document the current situation with regards to human resource development in eyecare in Mozambique and offer analysis of the status and challenges facing the only programme addressing the problem of uncorrected refractive error and low vision in Lusophone Africa through education. METHODS The extent of uncorrected refractive error and existing optometric services in Nampula Province will be extrapolated from the results from a Rapid Assessment of Refractive Error and a situational analysis. The challenges faced by the Mozambique Eyecare Programme will be analysed using results from a baseline survey of students, key informant interviews and analysis of optometric resources available that are published in Portuguese. RESULTS The research into the implementation of the Mozambique Eyecare Programme is ongoing. Results are currently unavailable, but relevant data and analyses emerging from current research within the next 6 months will be presented at the conference. CONCLUSION Human resource development for refractive service delivery in Lusophone Africa is key to the achievement of VISION 2020 goals in this region. Innovative models of education need to take into account the local need, legislative boundaries and situational constraints in order to successfully achieve desired outcomes within specified timeframes.
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- 2010
- Full Text
- View/download PDF
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