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628 results on '"Kong, Xiang‐yu"'

102. Heterogeneous Electrospinning Nanofiber Membranes with pH‐regulated Ion Gating for Tunable Osmotic Power Harvesting.

Author

Ling, Haoyang, Xin, Weiwen, Qian, Yongchao, He, Xiaofeng, Yang, Linsen, Chen, Weipeng, Wu, Yadong, Du, Huaqing, Liu, Yang, Kong, Xiang‐Yu, Jiang, Lei, and Wen, Liping

Subjects
ENERGY harvesting, OSMOTIC pressure, ELECTROSPINNING, NANOFLUIDIC devices, ION channels, ENERGY conversion
Abstract

Biological ion channels existing in organisms are critical for many biological processes. Inspired by biological ion channels, the heterogeneous electrospinning nanofiber membranes (HENM) with functional ion channels are constructed by electrospinning technology. The HENM successfully realizes ion‐gating effects, which can be used for tunable energy conversions. Introduction of pyridine and carboxylic acid groups into the HENM plays an important role in generating unique and stable ion transport behaviors, in which gates become alternative states of open and close, responding to symmetric/asymmetric pH stimulations. Then we used the HENM to convert osmotic energy into electric energy which reach a maximum value up to 12.34 W m−2 and the output power density of HENM‐based system could be regulated by ion‐gating effects. The properties of the HENM provide widespread potentials in application of smart nanofluidic devices, energy conversion, and water treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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111. Olfactory-Inspired Separation-Sensing Nanochannel-Based Electronics for Wireless Sweat Monitoring

Author

Wu, Yuge, Wang, Qi, Li, Xin, Li, Ke, Huang, Dehua, Zou, Kehan, Zhang, Zhehua, Qian, Yongchao, Zhu, Congcong, Kong, Xiang-Yu, and Wen, Liping

Abstract

Human sweat has the potential to be sufficiently utilized for noninvasive monitoring. Given the complexity of sweat secretion, the sensitivity and selectivity of sweat monitoring should be further improved. Here, we developed an olfactory-inspired separation-sensing nanochannel-based electronic for sensitive and selective sweat monitoring, which was simultaneously endowed with interferent separation and target detection performances. The special separation-sensing strategy imparts functional composite membranes with a high sensitivity of 113 mV dec–1for potassium detection. The excellent mechanical properties and conformability of the Kevlar aramid nanofiber layer bring well-wearing performances to realize continuous wireless sweat monitoring. The recognition between functional molecules and target ions is proved at the molecular level in detail in the article. The replacement of functional molecules proves the universality of the strategy for performance enhancement in intricate biofluid analysis systems.

Published
2025
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112. Study and Analysis of Longitudinal Equivalent Capacitance of Special Axial Internal Shield Continuous Winding Used in UHV Converter Transformers

Author

Zhang Liang-xian, Zhang zhao, Lu Wen, Kong Xiang-Yu, Zhang Shan-shan, and Zhang Xiao-mei

Subjects
Materials science, Electromagnetic coil, law, Shield, Electrode, Mechanics, Electric potential, Condensed Matter::Mesoscopic Systems and Quantum Hall Effect, Transformer, Capacitance, Electrical conductor, Finite element method, law.invention
Abstract

In this paper, the author accorded to the structure characteristics of the winding, put forward a kind of finite element method for calculating turn-to-turn capacitance, capacitance between bread and longitudinal equivalent capacitance, and longitudinal equivalent capacitance of axial internal shield continuous type, ordinary internal shield continuous type and conventional continuous type is compared and analyzed by use this method. The results show concluded that axial internal shield continuous winding has a larger longitudinal equivalent capacitance than other winding types, so it has more excellent anti-impulse performance.

Published
2020
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116. Large-scale, national, family-based epidemiological study on Helicobacter pyloriinfection in China: the time to change practice for related disease prevention

Author

Zhou, Xian-Zhu, Lyu, Nong-Hua, Zhu, Hui-Yun, Cai, Quan-Cai, Kong, Xiang-Yu, Xie, Pei, Zhou, Li-Ya, Ding, Song-Ze, Li, Zhao-Shen, and Du, Yi-Qi

Abstract

Background and aimsCurrent practice on Helicobacter pyloriinfection mostly focuses on individual-based care in the community, but family-based H. pylorimanagement has recently been suggested as a better strategy for infection control. However, the family-based H. pyloriinfection status, risk factors and transmission pattern remain to be elucidated.MethodsFrom September 2021 to December 2021, 10 735 families (31 098 individuals) were enrolled from 29 of 31 provinces in mainland China to examine family-based H. pyloriinfection, related factors and transmission pattern. All family members were required to answer questionnaires and test for H. pyloriinfection.ResultsAmong all participants, the average individual-based H. pyloriinfection rate was 40.66%, with 43.45% for adults and 20.55% for children and adolescents. Family-based infection rates ranged from 50.27% to 85.06% among the 29 provinces, with an average rate of 71.21%. In 28.87% (3099/10 735) of enrolled families, there were no infections; the remaining 71.13% (7636/10 735) of families had 1–7 infected members, and in 19.70% (1504/7636), all members were infected. Among 7961 enrolled couples, 33.21% had no infection, but in 22.99%, both were infected. Childhood infection was significantly associated with parental infection. Independent risk factors for household infection were infected family members (eg, five infected members: OR 2.72, 95% CI 1.86 to 4.00), living in highly infected areas (eg, northwest China: OR 1.83, 95% CI 1.57 to 2.13), and large families in a household (eg, family of three: OR 1.97, 95% CI 1.76 to 2.21). However, family members with higher education and income levels (OR 0.85, 95% CI 0.79 to 0.91), using serving spoons or chopsticks, more generations in a household (eg, three generations: OR 0.79, 95% CI 0.68 to 0.92), and who were younger (OR 0.57, 95% CI 0.46 to 0.70) had lower infection rates (p<0.05).ConclusionFamilial H. pyloriinfection rate is high in general household in China. Exposure to infected family members is likely the major source of its spread. These results provide supporting evidence for the strategic changes from H. pyloriindividual-based treatment to family-based management, and the notion has important clinical and public health implications for infection control and related disease prevention.

Published
2023
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125. Efficacy and safety of tocilizumab in COVID-19 patients

Author

Zheng, Kai-Lian, primary, Xu, Ying, additional, Guo, Yu-Feng, additional, Diao, Le, additional, Kong, Xiang-Yu, additional, Wan, Xiao-Jian, additional, Zhao, Feng, additional, Ning, Fang-Zheng, additional, Wang, Li-Bing, additional, Qiao, Fan, additional, Zhao, Jiang-Man, additional, Zhou, Jia-Huan, additional, Zhong, Yue-Qian, additional, Wu, Shou-Xin, additional, Chen, Yi, additional, Jin, Gang, additional, and Dong, Yu-Chao, additional

Published
2020
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129. Improved Ion Transport and High Energy Conversion through Hydrogel Membrane with 3D Interconnected Nanopores

Author

Chen, Weipeng, primary, Wang, Qin, additional, Chen, Jianjun, additional, Zhang, Qianru, additional, Zhao, Xiaolu, additional, Qian, Yongchao, additional, Zhu, Congcong, additional, Yang, Linsen, additional, Zhao, Yuanyuan, additional, Kong, Xiang-Yu, additional, Lu, Benzhuo, additional, Jiang, Lei, additional, and Wen, Liping, additional

Published
2020
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134. Biomimetic KcsA channels with ultra-selective K+ transport for monovalent ion sieving.

Author

Xin, Weiwen, Fu, Jingru, Qian, Yongchao, Fu, Lin, Kong, Xiang-Yu, Ben, Teng, Jiang, Lei, and Wen, Liping

Subjects
WATER purification, SIEVES, ACTIVATION energy, ENERGY conversion, ION channels, ELECTROSTATIC interaction, IONS
Abstract

Ultra-selective and fast transport of K+ are of significance for water desalination, energy conversion, and separation processes, but current bottleneck of achieving high-efficiency and exquisite transport is attributed to the competition from ions of similar dimensions and same valence through nanochannel communities. Here, inspired by biological KcsA channels, we report biomimetic charged porous subnanometer cages that enable ultra-selective K+ transport. For nanometer to subnanometer scales, conically structured double-helix columns exhibit typical asymmetric transport behaviors and conduct rapid K+ with a transport rate of 94.4 mmol m−2 h−1, resulting in the K+/Li+ and K+/Na+ selectivity ratios of 363 and 31, respectively. Experiments and simulations indicate that these results stem from the synergistic effects of cation-π and electrostatic interactions, which impose a higher energy barrier for Li+ and Na+ and lead to selective K+ transport. Our findings provide an effective methodology for creating in vitro biomimetic devices with high-performance K+ ion sieving. Materials for the selective transport of K+ have application in a variety of fields including water desalination and separation processes. Here the authors report charged porous subnanometer cages that are inspired in biological KcsA channels; high K+ transport rates and high K+/Li+ and K+/Na+ selectivity ratios are obtained, showing great potential in advanced sieving processes and efficient water treatments. [ABSTRACT FROM AUTHOR]

Published
2022
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136. Endosonographers performing on-site evaluation of solid pancreatic specimens for EUS-guided biopsy: A formal training method and learning curves

Author

Li, Shi-Yu, Gao, Li, Zhang, Ping-Ping, Su, Xiao-Ju, Kong, Xiang-Yu, Wang, Kai-Xuan, and Jin, Zhen-Dong

Subjects
ROSE, EUS-guided fine needle biopsy, Hepatology, endoscopy training, education, solid pancreatic lesions, Gastroenterology, Original Article, Radiology, Nuclear Medicine and imaging
Abstract

Objectives: This study aimed to examine the effects of a training program combining formal cytological curriculum and practical assessments on endosonographers and to determine how many operations were needed for training through learning curves. Methods: A formal cytological curriculum was implemented in November 2019 for four endosonographers. The competency of endosonographers before and after the curriculum was judged by quantitative scores. From December 2019 to October 2020, trainees independently examined the adequacy and atypia grade of pancreatic specimens acquired by EUS-guided-fine-needle biopsy based on specific atypical grading criteria. The accuracy of the adequacy and atypia assessment of each trainee was calculated, and learning curves were drawn to evaluate the improvement. Results: The median posttraining score improved by 87% from 49 to 91.5 out of 100. Ninety patients were enrolled in the practical assessments. The accuracy for specimen adequacy and atypia assessment of each trainee was 91.7%, 92.8%, 91.0%, and 89.3% and 80.0%, 82.1%, 81.0%, and 78.9%. The learning curves of each trainee showed a steady and significant improvement, and ninety cases were sufficient for satisfactory adequacy assessment. Conclusions: Basic knowledge of on-site cytopathologic evaluation can be gained through standardized and systematic training. Practical assessments showed that, at the completion of ninety cases, trained endosonographers reached a satisfactory level of recognizing specimen adequacy, but continue practice was needed for atypia assessment.

Published
2021
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145. GII.13/21 Noroviruses Recognize Glycans with a Terminal β-Galactose via an Unconventional Glycan Binding Site

Author

Cong, Xin, primary, Sun, Xiao-man, additional, Qi, Jian-xun, additional, Li, Han-bo, additional, Chai, Wen-gang, additional, Zhang, Qing, additional, Wang, Hong, additional, Kong, Xiang-yu, additional, Song, Jiao, additional, Pang, Li-li, additional, Jin, Miao, additional, Li, Dan-di, additional, Tan, Ming, additional, and Duan, Zhao-jun, additional

Published
2019
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146. Cement-and-pebble nanofluidic membranes with stable acid resistance as osmotic energy generators

Author

Zhao, Yifei, Xin, Weiwen, Qian, Yongchao, Zhang, Zhehua, Wu, Yadong, Lin, Xiangbin, Kong, Xiang-Yu, Jiang, Lei, and Wen, Liping

Abstract

Osmotic energy between river water and seawater has attracted interest as a new source of sustainable energy. Nanofluidic membranes in a reverse electrodialysis configuration can capture energy from salinity gradients. However, current membrane materials suffer from high resistances, low stabilities, and low charge densities, which limit their further application. Here, we designed a high-performance nanofluidic membrane using carboxylic cellulose nanofibers functionalized with graphene oxide nanolamellas with cement-and-pebble microstructures and stable skeletons for enhanced ion transmembrane transport. By mixing artificial river water and seawater, the composite membrane achieved a high output power density up to 5.26 W m−2. Additionally, the membrane had an excellent acid resistance, which enabled long-term use with over 67 W m−2of power density. The performance of this composite membrane benefited from the mechanically strong cellulose fibers and the bonding between nanofibers and nanolamellas. In this work, we highlight promising directions in industrial waste treatment using energy extracted from chemical potential gradients.

Published
2022
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147. A universal functionalization strategy for biomimetic nanochannel via external electric field assisted non-covalent interaction.

Author

Teng, Yunfei, Kong, Xiang-Yu, Liu, Pei, Qian, Yongchao, Hu, Yuhao, Fu, Lin, Xin, Weiwen, Jiang, Lei, and Wen, Liping

Abstract

Biological ion channels, as fundamental units participating in various daily behaviors with incredible mass transportation and signal transmission, triggered booming researches on manufacturing their artificial prototypes. Biomimetic ion channel with the nanometer scale for smart responding functions has been successfully realized in sorts of materials by employing state-of-art nanotechnology. Ion track-etching technology, as crucial branches of fabricating solid-state nanochannels, exhibits outstanding advantages, such as easy fabrication, low cost, and high customization. To endow the nanochannel with smart responsibility, various modification methods are developed, including chemical grafting, non-covalent adsorption, and electrochemical deposition, enriching the reservoir of accessible stimuli-responses combinations, whereas were limited by their relatively lengthy and complex procedure. Here, based on the electric field induced self-assembly of polyelectrolytes, a universal customizable modifying strategy has been proposed, which exhibits superiorities in their functionalization with convenience and compatibility. By using this protocol, the channels' ionic transport behaviors could be easily tuned, and even the specific ionic or molecular responding could be realized with superior performance. This strategy surely accelerates the nanochannels functionalization into fast preparing, high efficiency, and large-scale application scenarios. [ABSTRACT FROM AUTHOR]

Published
2021
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149. Smallest fullerene-like silicon cage stabilized by a V2 unit.

Author

Xu, Hong-Guang, Kong, Xiang-Yu, Deng, Xiao-Jiao, Zhang, Zeng-Guang, and Zheng, Wei-Jun

Subjects
*PHYSICS research, *PHOTOELECTRON spectroscopy, *CLUSTER theory (Nuclear physics), *FULLERENES, *DENSITY functional theory, *MOLECULAR theory, *NANOWIRES
Abstract

We conducted a combined anion photoelectron spectroscopy and density functional theory study on V2Si20 cluster. Our results show that the V2Si20 cluster has an elongated dodecahedron cage structure with a V2 unit encapsulated inside the cage. It is the smallest fullerene-like silicon cage and can be used as building block to make cluster-assembled materials, such as pearl-chain style nanowires. [ABSTRACT FROM AUTHOR]

Published
2014
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150. Photoelectron spectroscopy and density functional calculations of AgSin- (n = 3-12) clusters.

Author

Kong, Xiang-Yu, Deng, Xiao-Jiao, Xu, Hong-Guang, Yang, Zheng, Xu, Xi-Ling, and Zheng, Wei-Jun

Subjects
*PHOTOELECTRON spectroscopy, *MICROCLUSTERS, *DENSITY functional theory, *SILVER compounds, *ELECTRONIC structure, *ADIABATIC processes
Abstract

We investigated the structural evolution and electronic properties of AgSin- (n = 3-12) clusters using anion photoelectron spectroscopy and density functional theory calculations. The vertical detachment energies and adiabatic detachment energies of AgSin- (n = 3-12) clusters were estimated from their photoelectron spectra. The structures of the AgSin- (n = 3-12) clusters were tentatively assigned based on the comparison of theoretical calculations and experimental measurements. The studies show that the structures of AgSin- (n = 3-12) clusters are dominated by exohedral structures with the Ag atom occupying the low coordinated sites. No endohedral structure has been found for AgSin- clusters with n ≤ 12. [ABSTRACT FROM AUTHOR]

Published
2013
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