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1,073 results on '"Kobayashi, Masayoshi"'

102. Sinonasal Undifferentiated Carcinoma

Author

Ishigami, Eisuke, primary, Kobayashi, Masayoshi, additional, Nishida, Kohei, additional, Morishita, Hiroyuki, additional, Uchida, Katsunori, additional, Toyomasu, Yutaka, additional, and Takeuchi, Kazuhiko, additional

Published
2021
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108. CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy

Author

Hara, Ayaka, primary, Koyama-Nasu, Ryo, additional, Takami, Mariko, additional, Toyoda, Takahide, additional, Aoki, Takahiro, additional, Ihara, Fumie, additional, Kobayashi, Masayoshi, additional, Hirono, Seiichiro, additional, Matsutani, Tomoo, additional, Nakayama, Toshinori, additional, Iwadate, Yasuo, additional, and Motohashi, Shinichiro, additional

Published
2020
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113. A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs

Author

Pauty, Joris, Usuba, Ryo, Cheng, Irene Gayi, Hespel, Louise, Takahashi, Haruko, Kato, Keisuke, Kobayashi, Masayoshi, Nakajima, Hiroyuki, Lee, Eujin, Yger, Florian, Soncin, Fabrice, Matsunaga, Yukiko, Laboratory for Integrated Micro Mechatronics Systems (LIMMS), The University of Tokyo (UTokyo)-Centre National de la Recherche Scientifique (CNRS), Center for International Research on Integrative Biomedical Systems [University of Tokyo] (CIBiS), Institute of Industrial Science (IIS), The University of Tokyo (UTokyo)-The University of Tokyo (UTokyo), Clemson University, Département de Chimie - ENS Paris, École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640) (PASTEUR), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), SCREEN Holdings Co., Ltd. [Kyoto, Japan] (SHC), National Cerebral and Cardiovascular Center [Osaka, Japon] (N3C - Suita), Osaka University [Osaka], Laboratoire d'analyse et modélisation de systèmes pour l'aide à la décision (LAMSADE), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Mécanismes de la Tumorigénèse et Thérapies Ciblées - UMR 8161 (M3T), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), The University of Tokyo (UTokyo), Administrateur, Paris Dauphine-PSL, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), National cerebral and cardiovascular center research institute, and Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Université de Lille, Droit et Santé

Subjects
Niacinamide, Vascular Endothelial Growth Factor A, Indoles, Notch, Human umbilical vein endothelial cell, Angiogenesis inhibitors, Neovascularization, Physiologic, lcsh:Medicine, [INFO] Computer Science [cs], DLL4, In vitro 3D model, Models, Biological, Human Umbilical Vein Endothelial Cells, Sunitinib, Humans, [INFO]Computer Science [cs], Pyrroles, Microvessel, lcsh:R5-920, Phenylurea Compounds, lcsh:R, Sorafenib, Sprouting angiogenesis, Gene Knockdown Techniques, Microvessels, Blood Vessels, Biological Assay, Vascular endothelial growth factor, Corrigendum, lcsh:Medicine (General), Tomography, Optical Coherence, Signal Transduction
Abstract

International audience; Angiogenesis is the formation of new capillaries from pre-existing blood vessels and participates in proper vasculature development. In pathological conditions such as cancer, abnormal angiogenesis takes place. Angiogenesis is primarily carried out by endothelial cells, the innermost layer of blood vessels. The vascular endothelial growth factor-A (VEGF-A) and its receptor-2 (VEGFR-2) trigger most of the mechanisms activating and regulating angiogenesis, and have been the targets for the development of drugs. However, most experimental assays assessing angiogenesis rely on animal models. We report an in vitro model using a microvessel-on-a-chip. It mimics an effective endothelial sprouting angiogenesis event triggered from an initial microvessel using a single angiogenic factor, VEGF-A. The angiogenic sprouting in this model is depends on the Notch signaling, as observed in vivo. This model enables the study of anti-angiogenic drugs which target a specific factor/receptor pathway, as demonstrated by the use of the clinically approved sorafenib and sunitinib for targeting the VEGF-A/VEGFR-2 pathway. Furthermore, this model allows testing simultaneously angiogenesis and permeability. It demonstrates that sorafenib impairs the endothelial barrier function, while sunitinib does not. Such in vitro human model provides a significant complimentary approach to animal models for the development of effective therapies.

Published
2018
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119. Inhibition of baroreflex vagal bradycardia by nasal stimulation in rats

Author

Kobayashi, Masayoshi, Cheng, Zhi Bin, and Nosaka, Shoichiro

Subjects
Bradycardia -- Research, Sensory receptors -- Research, Rats -- Physiological aspects, Smoke -- Physiological aspects, Biological sciences
Abstract

The effect of intranasal sensory receptor activation on arterial baroreflex is analyzed. Control arterial baroreflexes were stimulated by using electrical stimulation of the aortic depressor nerve (ADN). To determine the possibility that inhibition of baroreflex vagal bradycardia was affected by the substantial smoke-evoked reduction in the baseline heart rate, responses to stimulation of the ADN with different intervals between the conditioning application of smoke and the test stimulation of ADN were investigated. The results are discussed.

Published
1999

140. Permeability and diffusivity of d-limonene vapor in polymeric sealant films

Author

Kobayashi, Masayoshi, Kanno, Tohru, Hanada, Katsutoshi, and Osanai, Shin-Ichi

Subjects
Packaging -- Research, Polyethylene -- Research, Permeability -- Analysis, Thermal diffusivity -- Analysis, Business, Food/cooking/nutrition
Abstract

Experimental studies help derive equation to evaluate the permeability and diffusivity of d-limonene vapor in various polymeric sealant films, as a function of q(s) or melting temperature (T(mp) of the films. Differential scanning calorimeter helps measure the melting temperature of the films. Films with higher barrier against loss of d-limonene have higher T(mp) and q(s). A temperature-programmed desorption technique helps measure the sorption of d-limonene.

Published
1995

141. Abstracts of selected papers presented at the 31st annual meeting of the Japanese Society of Gastroenterology October 5–7, 1989, Asahikawa, Japan

Author

Yagi, Kinji, Sugaya, Eiichi, Fusamoto, Hidcyuki, Kamada, Takenobu, Nakamura, Masahiko, Oda, Masaya, Uehara, Akira, Namiki, Masayoshi, Itoh, Kazuro, Matsuo, Yutaka, Yoshikawa, Toshikazu, Suematsu, Makoto, Kurose, Iwao, Sekiya, Chihiro, Kohda, Hironobu, Narumi, Shunji, Takahashi, Ken-ichi, Sasaki, Mutsuo, Ono, Keiichi, Manabe, Tadao, Ohshio, Gakuji, Iishi, Hiroyasu, Tatsuta, Masaharu, Fuchigami, Tadahiko, Iwashita, Akinori, Sekoguchi, Tsutomu, Inamori, Shigeharu, Ajioka, Yoichi, Watanabe, Hidenobu, Masaki, Tadahiko, Suzuki, Kimitaka, Shimamoto, Chikao, Hirata, Ichiro, Hinoda, Yuji, Yachi, Akira, Kijima, Hiroshi, Watanabe, Hidenobu, Yamao, Kenji, Nakazawa, Saburo, Wada, Yoshiyuki, Semba, Daisuke, Saito, Akiko, Obata, Hiroshi, Tarao, Kazuo, Shimizu, Akio, Hirohashi, Setsuo, Fujiyama, Shigetoshi, Izuno, Kiyonori, Matsui, Osamu, Kadoya, Masumi, Fukuda, Morimichi, Mima, Satoaki, Oi, Hiromichi, Nakamura, Hironobu, Itani, Kenji, Yoshikawa, Toshikazu, Ebara, Masaaki, Ohto, Masao, Takasaki, Ken, Aruga, Atsushi, Okuda, Koji, Nakayama, Toshimichi, Arii, Shigcki, Tobe, Takayoshi, Nonami, Toshiaki, Takagi, Hiroshi, Mayumi, Toshihiko, Hachisuka, Kitao, Aoike, Akira, Nakamura, Keiya, Nagahata, Yoshi, Saitoh, Yoichi, Iwasaki, Ariyoshi, Aizawa, Toshiharu, Sato, Nobuhiro, Kawano, Sunao, Shibata, Yoshimi, Okamura, Kiyoshi, Hori, Shinji, Yamamura, Makoto, Akimoto, Shin, Igarashi, Tatsuki, Takase, Kojiro, Tameda, Yukihiko, Nakajima, Yasuaki, Uchino, Junichi, Noro, Toshio, Yamashiro, Moriya, Miyake, Hirofumi, Matsumoto, Shuji, Higashiguchi, Takashi, Ogura, Yoshifumi, Hayashi, Hiroto, Suzuki, Takashi, Higashiguchi, Takashi, Ogura, Yoshifumi, Hayashi, Hiroto, Suzuki, Takashi, Kumashiro, Ryukichi, Tanikawa, Kyuichi, Adachi, Yukihiko, Yamamoto, Toshio, Izawa, Kunihide, Tsuchiya, Ryoichi, Inui, Kazuo, Nakazawa, Saburo, Suyama, Masafumi, Ariyama, Jo, Nakasako, Toshiaki, Hanyu, Fujio, Imaizumi, Toshihide, Matsuda, Yoshiaki, Hasebe, Osamu, Noguchi, Takashi, Mizumoto, Ryuji, Matsueda, Kei, Umeda, Noritsugu, Hongo, Michio, Harasawa, Shigeru, Takayasu, Hiroyuki, Kusano, Motoyasu, Sekiguchi, Toshikazu, Okano, Hiroyuki, Saeki, Susumu, Shimada, Akira, Nakagawa, Tetsuya, Ozaki, Shoichi, Kobayashi, Kenzo, Fukudo, Shin, Suzuki, Jinichi, Sasaki, Daisuke, Kawasaki, Masatoshi, Kasai, Fukio, Takebe, Kazuo, Kobayashi, Masayoshi, Kawarada, Hiroaki, Ochiai, Takumi, Nagahama, Akira, Tsuji, Kagetoshi, Himeno, Seiichi, Toyosaka, Akihiro, and Okamoto, Eizo

Published
1991
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143. Buerger’s disease in a 19-year-old woman

Author

Matsushita, Masahiro, Kuzuya, Akihiko, Kobayashi, Masayoshi, Nishikimi, Naomichi, Ito, Masafumi, Oba, Yasuhiro, Yano, Takashi, and Komori, Kimihiro

Published
2003

145. A new patterning process concept for large-area transistor circuit fabrication without using an optical mask aligner

Author

Mikami, Yoshiro, Nagae, Yoshiharu, Mori, Yuji, Kuwabara, Kazuhiro, Saito, Takeshi, Hayama, Hiroshi, Asada, Hideki, Akimoto, Yasumasa, Kobayashi, Masayoshi, Okazaki, Satoshi, Asaka, Kenji, Matsui, Hiroyuki, Nakamura, Kazunori, and Kaneko, Eiji

Subjects
Transistor circuits -- Design and construction, Offset printing -- Usage, Business, Electronics, Electronics and electrical industries
Abstract

An improved gravure offset printing scheme and a double-layer print resist method yielded cost-effective TFT-LCD with high throughput. The gravure offset printing technique facilitated the patterning of a 10 micrometer design width on a glass substrate. The double-layer resist technique enabled the fabrication of decontaminated TFTs.

Published
1994

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