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102. Der Einfluss der verlängerten Einatmungszeit auf den Gasaustausch bei der robotergestützten laparoskopischen urologischen Chirurgie.

Author

Hur, M., Park, S.-K., Jung, D. E., Yoo, S., Choi, J.-Y., Kim, W. H., Kim, J. T., and Bahk, J.-H.

Subjects
PULMONARY gas exchange, LAPAROSCOPIC surgery, HYPERCAPNIA, UROLOGICAL surgery, PNEUMOPERITONEUM
Abstract

Background: Gas exchange disturbance may develop during urologic robotic laparoscopic surgery with the patient in a steep Trendelenburg position. This study investigated whether prolonged inspiratory time could mitigate gas exchange disturbances including hypercapnia.Methods: In this randomized cross-over trial, 32 patients scheduled for robot-assisted urologic surgery were randomized to receive an inspiratory to expiratory time ratio (I:E) of 1:1 for the first hour of pneumoperitoneum followed by 1:2 for last period of surgery (group A, n = 17) or I:E of 1:2 followed by 1:1 (group B, n = 15). Arterial blood gas analysis, airway pressure and hemodynamic variables were assessed at four time points (T1: 10 min after induction of general anesthesia, T2: 1 h after the initiation of pneumoperitoneum, T3: 1 h after T2 and T4: at skin closure). The carry over effect of initial I:E was also evaluated over the next hour through arterial blood gas analysis.Results: There was a significant decrease in partial pressure of oxygen in arterial blood (PaO2) for both groups at T2 and T3 compared to T1 but in group B the PaO2 at T4 was not decreased from the baseline. Partial pressure of carbon dioxide in arterial blood (PaCO2) increased with I:E of 1:2 but did not significantly increase with I:E of 1:1; however, there were no differences in PaO2 and PaCO2 between the groups.Conclusion: Decreased oxygenation by pneumoperitoneum was improved and PaCO2 did not increase after 1 h of I:E of 1:1; however, the effect of equal ratio ventilation longer than 1 h remains to be determined. There was no carryover effect of the two different I:E ratios. [ABSTRACT FROM AUTHOR]

Published
2018
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103. Wavelet based multi-scale shape features on arbitrary surfaces for cortical thickness discrimination

Author

Kim, W. H., Pachauri, D., Hatt, C., Moo Chung, Johnson, S. C., and Singh, V.

Subjects
Article
Abstract

Hypothesis testing on signals defined on surfaces (such as the cortical surface) is a fundamental component of a variety of studies in Neuroscience. The goal here is to identify regions that exhibit changes as a function of the clinical condition under study. As the clinical questions of interest move towards identifying very early signs of diseases, the corresponding statistical differences at the group level invariably become weaker and increasingly hard to identify. Indeed, after a multiple comparisons correction is adopted (to account for correlated statistical tests over all surface points), very few regions may survive. In contrast to hypothesis tests on point-wise measurements, in this paper, we make the case for performing statistical analysis on multi-scale shape descriptors that characterize the local topological context of the signal around each surface vertex. Our descriptors are based on recent results from harmonic analysis, that show how wavelet theory extends to non-Euclidean settings (i.e., irregular weighted graphs). We provide strong evidence that these descriptors successfully pick up group-wise differences, where traditional methods either fail or yield unsatisfactory results. Other than this primary application, we show how the framework allows performing cortical surface smoothing in the native space without mappint to a unit sphere.

Published
2012

104. Nonphotochemical hole burning in hyperquenched glassy films of water: A pronounced deuteration effect.

Author

Kim, W.-H., Reinot, T., Hayes, J. M., and Small, G. J.

Subjects
*OPTICAL hole burning, *METALLIC glasses, *WATER, *DEUTERON scattering
Abstract

The effects of deuteration on hole burning of aluminum phthalocyanine tetrasulfonate (APT) in glassy films of water is reported. Deuteration has no effect on the zero phonon hole width of the APT electronic transition, but a large effect on the hole burning kinetics. These effects are discussed in terms of the two level systems of glassy water. © 1996 American Institute of Physics. [ABSTRACT FROM AUTHOR]

Published
1996
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112. Highly Reliable Flip-Chip-on-Flex Package Using Multilayered Anisotropic Conductive Film.

Author

Myung Jin Yim, W. H., Jin-Sang Hwang, W. H., Jin Gu Kim, W. H., Jin Yong Ahn, W. H., Hyung Joon Kim, W. H., Woonseong Kwon, W. H., and Kyung-Wook Paik

Subjects
ANISOTROPY, LIQUID crystal displays, ADHESION, WETTING, INTEGRATED circuits
Abstract

Anisotropic conductive film (ACF) has been used as interconnect material for flat-panel display module packages, such as liquid crystal displays (LCDs) in the technologies of tape automated bonding (TAB), chip-on-glass (COG), chipon film (COF), and chip-on-board (COB). Among them, COF is a relatively new technology after TAB and COG bonding, and its requirement for ACF becomes more stringent because of the need of high adhesion and fine-pitch interconnection. To meet these demands, strong interfacial adhesion between the ACF, substrate, and chip is a major issue. We have developed a multilayered ACF that has functional layers on both sides of a conventional ACF layer to improve the wetting properties of the resin on two-layer flex for better interface adhesion and to control the flow of conductive particles during thermocompression bonding and the resulting reliability of the interconnection using ACF. To investigate the enhancement of electrical properties and reliability of multilayered ACF in COF assemblies, we evaluated the performance in contact resistance and adhesion strength of a multilayered ACF and single-layered ACF under various environmental tests, such as a thermal cycling test (-55°C/+160°C, 1,000 cycles), a high-temperature humidity test (85°C/85% RH, 1,000 h), and a high-temperature storage test (150°C, 1,000 h). The contact resistance of the multilayered ACF joint was in an acceptable range of around a 10% increase of the initial value during the 85°C/85% RH test compared with the single-layered ACF because of the stronger moisture resistance of the multilayered ACF and flex substrate. The multilayered ACF has better adhesion properties compared with the conventional single-layered ACF during the 85°C/85% RH test because of the enhancement of the wetting to the surface of the polymide (PI) flex substrate with an adhesion-promoting nonconductive film (NCF) layer of multilayered ACF. The new ACF of the multilayered... [ABSTRACT FROM AUTHOR]

Published
2004
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113. Microstructure and Strength of Bump Joints in Photodiode Packages.

Author

Kyung-Seob Kim, W. H., Nam-Kyu Kim, W. H., Chung-Hee Yu, W. H., Joong-Jung Kim, W. H., and Eui-Goo Chang

Subjects
STRENGTH of materials, MECHANICS (Physics), JOINTS (Engineering), INTERMETALLIC compounds, PHOTODIODES, TRANSMISSION electron microscopy
Abstract

The joint strength and fracture surfaces of Sn-Pb and Au stud bumps for photodiode packages after isothermal aging were studied experimentally. Aluminum/gold stud bumps and Cu/Sn-Pb solders were adopted and aged for up to 900 h to analyze the effect of intermetallic compound (IMC) formation. The joint strength decreased with aging time. The diffraction patterns of Cu6Sn5, scallop-shaped IMCs, and planar-shaped Cu3Sn were characterized by transmission electron microscopy (TEM). The IMCs between Au stud bumps and A1 pads was identified as AlAu2. The formation of Kirkendall voids and the growth of IMCs at the solder joint were found to be a possible mechanism for joint strength reduction. [ABSTRACT FROM AUTHOR]

Published
2004
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120. Incidence and clinical features ofClostridium difficileinfection in Korea: a nationwide study

Author

KIM, Y. S., primary, HAN, D. S., additional, KIM, Y. H., additional, KIM, W. H., additional, KIM, J. S., additional, KIM, H. S., additional, PARK, Y. S., additional, SONG, H. J., additional, SHIN, S. J., additional, YANG, S. K., additional, YE, B. D., additional, EUN, C. S., additional, LEE, K. M., additional, LEE, S. H., additional, JANG, B. I., additional, JUNG, S. A., additional, CHEON, J. H., additional, CHOI, C. H., additional, and HUH, K. C., additional

Published
2012
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124. Cardiovascular complications in CKD 5D (1)

Author

Kuo, K.-L., primary, Hung, S.-C., additional, Tarng, D.-C., additional, Selim, G., additional, Stojceva-Taneva, O., additional, Tozija, L., additional, Gelev, S., additional, Stojcev, N., additional, Dzekova, P., additional, Trajcevska, L., additional, Severova, G., additional, Pavleska, S., additional, Sikole, A., additional, Combe, C., additional, Thumma, J., additional, Gillespie, B., additional, De Sequera, P., additional, Yamamoto, H., additional, Robinson, B., additional, Matsushita, Y., additional, Tasaki, H., additional, Tohara, Y., additional, Yamauchi, E., additional, Matsuoka, K., additional, Arizono, K., additional, Bellasi, A., additional, Ferramosca, E., additional, Ratti, C., additional, Block, G., additional, Raggi, P., additional, Drozdz, M., additional, Krasniak, A., additional, Chmiel, G., additional, Podolec, P., additional, Pasowicz, M., additional, Tracz, W., additional, Kowalczyk-Michalek, M., additional, Sulowicz, W., additional, Kalantzi, K., additional, Korantzopoulos, P., additional, Bechlioulis, A., additional, Vlachopanou, A., additional, Foulidis, V., additional, Pagiati, E., additional, Nikolopoulos, P., additional, Gouva, C., additional, Arroyave, I., additional, Rodelo, J., additional, Cardona, M., additional, Garcia, A., additional, Henao, J., additional, Mejia, G., additional, Rico, J., additional, Arbelaez, M., additional, Fujimori, A., additional, Okada, S., additional, Yamamoto, K., additional, Okamoto, S., additional, Kamiura, N., additional, Sakai, M., additional, Tanikake, M., additional, Kutlay, S., additional, Sengul, S., additional, Keven, K., additional, Nergizoglu, G., additional, Erturk, S., additional, Ates, K., additional, Duman, N., additional, Karatan, O., additional, Erbay, B., additional, Sameiro-Faria, M., additional, Costa, E., additional, Rocha-Pereira, P., additional, Borges, A., additional, Nascimento, H., additional, Mendonca, D., additional, Amado, L., additional, Reis, F., additional, Miranda, V., additional, Quintanilha, A., additional, Belo, L., additional, Santos-Silva, A., additional, Oh, J. S., additional, Kim, S. M., additional, Sin, Y. H., additional, Kim, J. K., additional, Ishihara, M., additional, Otsubo, S., additional, Kimata, N., additional, Akiba, T., additional, Nitta, K., additional, Kim, K. M., additional, Baek, C. H., additional, Kim, S. B., additional, Testa, A., additional, Sanguedolce, M. C., additional, Spoto, B., additional, Mallamaci, F., additional, Malatino, L., additional, Tripepi, G., additional, Zoccali, C., additional, Lee, J. E., additional, Moon, S. J., additional, Kim, J.-K., additional, An, H. R., additional, Ha, S. K., additional, Pakr, H. C., additional, Bahlmann, F. H., additional, Becker, E., additional, Sperber, V., additional, Triem, S., additional, Noll, C., additional, Zewinger, S., additional, Fliser, D., additional, Laufs, U., additional, Thijssen, S., additional, Usvyat, L. A., additional, Raimann, J. G., additional, Balter, P., additional, Kotanko, P., additional, Levin, N. W., additional, Hornum, M., additional, Bay, J. T., additional, Clausen, P., additional, Melchior Hansen, J., additional, Mathiesen, E. R., additional, Feldt-Rasmussen, B., additional, Garred, P., additional, Sural, S., additional, Panja, C. S., additional, Bhattacharya, S. K., additional, Cernaro, V., additional, Lacquaniti, A., additional, Lorenzano, G., additional, Romeo, A., additional, Donato, V., additional, Buemi, M., additional, Usvyat, L., additional, Rogus, J., additional, Lacson, E., additional, Robinson, B. M., additional, Karaboyas, A., additional, Sen, A., additional, Hecking, M., additional, Mendelssohn, D., additional, Jadoul, M., additional, Kawanishi, H., additional, Saran, R., additional, Kolarz, M., additional, Undas, A., additional, Wyroslak, J., additional, Malyszko, J., additional, Klejna, K., additional, Naumnik, B., additional, Koc-Zurawska, E., additional, Mysliwiec, M., additional, Piecha, G., additional, Kuczera, P., additional, Adamczak, M., additional, Fedorova, O. V., additional, Bagrov, A. Y., additional, Wiecek, A., additional, Gungor, O., additional, Kircelli, F., additional, Asci, G., additional, Carrero, J. J., additional, Tatar, E., additional, Demirci, M., additional, Toz, H., additional, Ozkahya, M., additional, Ok, E., additional, Bansal, V., additional, Shareain, K., additional, Hoppensteadt, D., additional, Litinas, E., additional, Fareed, J., additional, Kim, M.-J., additional, Lee, S. W., additional, Song, J. H., additional, Kweon, J., additional, Kim, W. H., additional, Sasaki, K., additional, Yasuda, K., additional, Hatanaka, M., additional, Hayashi, T., additional, Katsipi, I., additional, Tatsiopoulos, A., additional, Papanikolaou, P., additional, Doulgerakis, C., additional, Kollia, K., additional, Kardouli, E., additional, Asmanis, E., additional, Gennadiou, M., additional, Kyriazis, J., additional, Panizo, S., additional, Barrio-Vazquez, S., additional, Carrillo-Lopez, N., additional, Fernandez-Vazquez, A., additional, Braga, S., additional, Rodriguez-Rebollar, A., additional, Naves-Diaz, M., additional, Cannata-Andia, J. B., additional, Nikodimopoulou, M., additional, Liakos, S., additional, and Kapoulas, S., additional

Published
2011
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125. Determinants of Epstein-Barr virus-positive gastric cancer: an international pooled analysis

Author

Camargo, M C, primary, Murphy, G, additional, Koriyama, C, additional, Pfeiffer, R M, additional, Kim, W H, additional, Herrera-Goepfert, R, additional, Corvalan, A H, additional, Carrascal, E, additional, Abdirad, A, additional, Anwar, M, additional, Hao, Z, additional, Kattoor, J, additional, Yoshiwara-Wakabayashi, E, additional, Eizuru, Y, additional, Rabkin, C S, additional, and Akiba, S, additional

Published
2011
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131. Increasing Nodal Ratio is a Poor Prognostic Factor for Survival in Stage III-IV (M0) Gastric Cancer Patients Who Received Curative Surgery Followed by Adjuvant Chemotherapy: A Retrospective Study

Author

Kim, J.-S., primary, Kim, M.-A., additional, Oh, D.-Y., additional, Lee, S.-H., additional, Kim, D.-W., additional, Im, S.-A., additional, Kim, W. H., additional, Yang, H.-K., additional, Heo, D. S., additional, Bang, Y.-J., additional, Lee, K.-U., additional, and Kim, T.-Y., additional

Published
2010
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139. Biomarker analysis in stage III–IV (M0) gastric cancer patients who received curative surgery followed by adjuvant 5-fluorouracil and cisplatin chemotherapy: epidermal growth factor receptor (EGFR) associated with favourable survival

Author

Kim, J-S, primary, Kim, M-A, additional, Kim, T M, additional, Lee, S-H, additional, Kim, D-W, additional, Im, S-A, additional, Kim, T-Y, additional, Kim, W H, additional, Yang, H-K, additional, Heo, D S, additional, Bang, Y-J, additional, Lee, K-U, additional, Choe, K-J, additional, and Kim, N K, additional

Published
2009
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141. Interface reaction and characterization in B/Al composites

Author

Kim, W. H, Koczak, M. J, and Lawley, A

Subjects
Composite Materials
Abstract

Interfacial reactions, strength degradation, and fracture morphology have been characterized in B/Al(1100) and B/Al(6061) composite systems at a volume fraction of 0.55. Reaction was promoted by isothermal exposure at 350 C or 500 C for times up to 860,000 s. Tetragonal AlB12 was identified as the reaction product in the 6061 matrix and hexagonal AlB2 in the 1100 matrix. Interface development is analyzed based on a moving boundary model modified by the addition of ternary elements. While strength decreases in both systems, the time dependence of elevated-temperature exposure is different in the two matrix materials. In the 45 deg fiber orientation, failure occurs primarily by matrix shear, whereas in the 90 deg fiber orientation, fracture morphology is characterized by a mixture of fiber splitting, ductile matrix fracture, and failure at fiber-matrix interfaces.

Published
1978

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