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101. A Risk Prediction Model for Operative Mortality after Heart Valve Surgery in a Korean Cohort

Author

Kim, Ho Jin, primary, Kim, Joon Bum, additional, Kim, Seon-Ok, additional, Yun, Sung-Cheol, additional, Lee, Sak, additional, Lim, Cheong, additional, Choi, Jae Woong, additional, Hwang, Ho Young, additional, Kim, Kyung Hwan, additional, Lee, Seung Hyun, additional, Yoo, Jae Suk, additional, Sung, Kiick, additional, Je, Hyung Gon, additional, Hong, Soon Chang, additional, Kim, Yun Jung, additional, Kim, Sung-Hyun, additional, and Chang, Byung-Chul, additional

Published
2021
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107. Added diagnostic values of three-dimensional high-resolution proton density-weighted magnetic resonance imaging for unruptured intracranial aneurysms in the circle-of-Willis: Comparison with time-of-flight magnetic resonance angiography

Author

Yim, Younghee, primary, Jung, Seung Chai, additional, Kim, Jung Youn, additional, Kim, Seon-Ok, additional, Kim, Byung Jun, additional, Lee, Deok Hee, additional, Park, Wonhyoung, additional, Park, Jung Cheol, additional, and Ahn, Jae Sung, additional

Published
2020
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110. Superiority of Epstein-Barr Virus DNA in the Plasma Over Whole Blood for Prognostication of Extranodal NK/T Cell Lymphoma

Author

Ha, Joo Young, primary, Cho, Hyungwoo, additional, Sung, Heungsup, additional, Jung, Ah Ra, additional, Lee, Yoon Sei, additional, Lee, Sang-Wook, additional, Ryu, Jin-Sook, additional, Chae, Eun Jin, additional, Kim, Kyung Won, additional, Huh, Jooryung, additional, Park, Chan-Sik, additional, Kim, Dong-Joon, additional, Kim, Seon-Ok, additional, and Yoon, Dok Hyun, additional

Published
2020
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111. A Risk Prediction Model for Operative Mortality after Heart Valve Surgery in a Korean Cohort

Author

Kim, Ho Jin, primary, Kim, Joon Bum, additional, Kim, Seon-Ok, additional, Yun, Sung-Cheol, additional, Lee, Sak, additional, Lim, Cheong, additional, Choi, Jae Woong, additional, Hwang, Ho Young, additional, Kim, Kyung Hwan, additional, Lee, Seung Hyun, additional, Yoo, Jae Suk, additional, Sung, Kiick, additional, Je, Hyung Gon, additional, Hong, Soon Chang, additional, Kim, Yun Jung, additional, Kim, Sung-Hyun, additional, and Chang, Byung-Chul, additional

Published
2020
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113. Determinants of clinical outcomes of surgery for isolated severe tricuspid regurgitation

Author

Park, Sung Jun, primary, Oh, Jin Kyung, additional, Kim, Seon-Ok, additional, Lee, Seung-Ah, additional, Kim, Ho Jin, additional, Lee, Sahmin, additional, Jung, Sung Ho, additional, Song, Jong-Min, additional, Choo, Suk Jung, additional, Kang, Duk-Hyun, additional, Chung, Cheol Hyun, additional, Song, Jae-Kwan, additional, Lee, Jae Won, additional, Kim, Dae-Hee, additional, and Kim, Joon Bum, additional

Published
2020
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116. Estimating Recurrence after Upfront Surgery in Patients with Resectable Pancreatic Ductal Adenocarcinoma by Using Pancreatic CT: Development and Validation of a Risk Score

Author

Kim, Dong Wook, primary, Lee, Seung Soo, additional, Kim, Seon-Ok, additional, Kim, Jin Hee, additional, Kim, Hyoung Jung, additional, Byun, Jae Ho, additional, Yoo, Changhoon, additional, Kim, Kyu-pyo, additional, Song, Ki-Byung, additional, and Kim, Song Cheol, additional

Published
2020
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119. 61 EFFICACY AND SAFETY OF EUS-GUIDED ANTEGRADE COVERED STENT PLACEMENT WITH LONG DUODENAL EXTENSION FOR MALIGNANT DISTAL BILIARY OBSTRUCTION: A MULTICENTER PILOT STUDY

Author

So, Hoonsub, primary, Oh, Dongwook, additional, Minaga, Kosuke, additional, Takenaka, Mamoru, additional, Uemura, Shinya, additional, Iwashita, Takuji, additional, Saito, Tomotaka, additional, Nakai, Yousuke, additional, Kim, Seon-Ok, additional, and Park, Do Hyun, additional

Published
2020
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120. Similar negative emotional impact on hair loss in neoadjuvant endocrine therapy compared to neoadjuvant chemotherapy in young women with breast cancer from patient reported outcomes.

Author

Gwark, Sung-chan, primary, Ahn, Sei Hyun, additional, Noh, Woo Chul, additional, Lee, Eun Sook, additional, Jung, Yongsik, additional, Kim, Lee Su, additional, Han, Wonshik, additional, Nam, Seok Jin, additional, Gong, Gyungyub, additional, Kim, Seon-Ok, additional, and Kim, Hee Jeong, additional

Published
2020
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121. Neoadjuvant endocrine therapy versus neoadjuvant chemotherapy in young women with breast cancer: Prognosis and axillary node surgery.

Author

Gwark, Sung-chan, primary, Ahn, Sei Hyun, additional, Ahn, Jin-Hee, additional, Jung, Kyung Hae, additional, Kim, Sung-Bae, additional, Gong, Gyungyub, additional, Lee, Sae Byul, additional, Kim, Jisun, additional, Chung, Il Yong, additional, Ko, Beom Seok, additional, Lee, jong Won, additional, Son, Byung Ho, additional, Kim, Seon-Ok, additional, and Kim, Hee Jeong, additional

Published
2020
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128. Determinants of left ventricular function improvement for cardiac resynchronization therapy candidates.

Author

Hong, Jung Ae, Lee, Sang Eun, Kim, Seon‐Ok, Kim, Min‐Seok, Lee, Hae‐Young, Cho, Hyun‐Jai, Choi, Jin Oh., Jeon, Eun‐Seok, Hwang, Kyung‐Kuk, Chae, Shung Chull, Baek, Sang Hong, Kang, Seok‐Min, Choi, Dong‐Ju, Yoo, Byung‐Su, Kim, Kye Hun, Cho, Myeong‐Chan, Oh, Byung‐Hee, and Kim, Jae‐Joong

Subjects
HEART failure patients, CARDIAC pacing
Abstract

Aims: A waiting period of more than 3 months is recommended for patients before undergoing cardiac resynchronization therapy (CRT). However, due to an anticipated high mortality rate, early implementation of CRT might be beneficial for some patients. We aimed to evaluate the rate and the probability of left ventricular (LV) function improvement and their predictors in patients with heart failure (HF) with indications for CRT. Methods and results: From March 2011 to February 2014, a total of 5625 hospitalized patients for acute HF were consecutively enrolled in 10 tertiary hospitals. Among them, we analysed 1792 patients (mean age 63.96 ± 15.42 years, female 63.1%) with left ventricular ejection fraction (LVEF) ≤ 35% at the baseline echocardiography and divided them into three groups: 144 with left bundle branch block (LBBB), 136 with wide QRS complexes without LBBB, and 1512 not having these findings (control). We compared and analysed these three groups for improvement of LV function at follow‐up echocardiography. In patients who met CRT indications (patients with LBBB or wide QRS complexes without LBBB), logistic regression was performed to identify risk factors for no improvement of LV. No improvement of LV was defined as LVEF ≤ 35% at follow‐up echocardiography or the composite adverse outcomes: death, heart transplantation, extracorporeal membrane oxygenation, or use of a ventricular assist device before follow‐up echocardiography. A classification tree was established using the binary recursive partitioning method to predict the outcome of patients who met CRT indications. In a median follow‐up of 11 months, LVEF improvement was observed in 24.3%, 15.4%, and 40.5% of patients with LBBB, wide QRS complexes without LBBB, and control, respectively. Patients meeting CRT indications had higher 3 month mortality rates than the control (24.6% vs. 17.7%, P = 0.002). Multivariable logistic regression analysis revealed that large LV end‐systolic dimension [odds ratio (OR) 1.10, 95% confidence interval (CI) 1.05–1.15, P < 0.001], low LVEF (OR 0.92, 95% CI 0.87–0.98, P = 0.006), diabetes requiring insulin (OR 6.49, 95% CI 2.53–19.33, P < 0.001), and suboptimal medical therapy (OR 6.85, 95% CI 3.21–15.87, P < 0.001) were significant factors predictive of no improvement. A decision tree analysis was consistent with these results. Conclusions: Patients with CRT indications had higher mortality during their follow‐up compared with control. LV function improvement was rare in this population, especially when they had some risk factors. These results suggest that the uniform waiting period before CRT implantation could be reconsidered and individualized. [ABSTRACT FROM AUTHOR]

Published
2022
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133. Superiority of Epstein-Barr Virus (EBV) DNA in the Plasma over Whole Blood in Prognostication of Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL)

Author

Ha, Joo Young, primary, Sung, Heungsup, additional, Jung, Ah Ra, additional, Lee, Yoon Sei, additional, Lee, Sang-wook, additional, Ryu, Jin-Sook, additional, Chae, Eun Jin, additional, Kim, Kyoung Won, additional, Huh, Jooryung, additional, Park, Chan-Sik, additional, Kim, Dong-Joon, additional, Kim, Seon-Ok, additional, Suh, Cheolwon, additional, and Yoon, Dok Hyun, additional

Published
2019
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134. Incidence and risk factors ofPneumocystis jiroveciipneumonia in Korean patients with inflammatory bowel disease

Author

Nam, Kwangwoo, primary, Park, Sang Hyoung, additional, Lee, Junghwan, additional, Jo, Seokjung, additional, Kim, Seon‐Ok, additional, Noh, Soomin, additional, Park, Jae Cheol, additional, Kim, Jin Yong, additional, Kim, Jeongseok, additional, Ham, Nam Seok, additional, Oh, Eun Hye, additional, Song, Eun Mi, additional, Hwang, Sung Wook, additional, Yang, Dong‐Hoon, additional, Ye, Byong Duk, additional, Byeon, Jeong‐Sik, additional, Myung, Seung‐Jae, additional, and Yang, Suk‐Kyun, additional

Published
2019
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143. Smoking, longer disease duration and absence of rhinosinusitis are related to fixed airway obstruction in Koreans with severe asthma: findings from the COREA study

Author

Moon Hee-Bom, Cho Sang-Heon, Kim Seon Ok, Kim Tae-Bum, Bae Yun-Jeong, Lee Yoon Su, Lee Taehoon, and Cho You Sook

Subjects
Diseases of the respiratory system, RC705-779
Abstract

Abstract Background The clinical manifestations of severe asthma are heterogeneous. Some individuals with severe asthma develop irreversible fixed airway obstruction, which is associated with poor outcomes. We therefore investigated the factors associated with fixed airway obstruction in Korean patients with severe asthma. Methods Severe asthma patients from a Korean adult asthma cohort were divided into two groups according to the results of serial pulmonary function tests. One group had fixed airway obstruction (FAO) [forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) ratio < 0.7, n = 119] and the other had reversible airway obstruction (RAO) [FEV1/FVC ratio ≥ 0.7, n = 116]. Clinical and demographic parameters were compared between the two groups. Results Multivariate analysis showed that longer duration of disease, greater amount of cigarette smoking and absence of rhinosinusitis were significantly related to the development of FAO in severe asthmatics. Other parameters, including atopic status, pattern of airway inflammatory cells in induced sputum, and frequency of asthma exacerbations did not differ between the FAO and RAO groups. Conclusion Severe asthma patients with longer disease duration and the absence of rhinosinusitis are more likely to develop FAO. This study also demonstrates the importance of quitting smoking in order to prevent irreversible airway obstruction. Further investigation is required to determine the mechanism by which these factors can modify the disease course in Korean patients with severe asthma.

Published
2011
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145. Determinants of clinical outcomes of surgery for isolated severe tricuspid regurgitation.

Author

Sung Jun Park, Jin Kyung Oh, Seon-Ok Kim, Seung-Ah Lee, Ho Jin Kim, Sahmin Lee, Sung Ho Jung, Jong-Min Song, Suk Jung Choo, Duk-Hyun Kang, Cheol Hyun Chung, Jae-Kwan Song, Jae Won Lee, Dae-Hee Kim, Joon Bum Kim, Park, Sung Jun, Oh, Jin Kyung, Kim, Seon-Ok, Lee, Seung-Ah, and Kim, Ho Jin

Subjects
TRICUSPID valve surgery, TREATMENT effectiveness, MARKOV chain Monte Carlo, HEART valve diseases, HEART transplantation, BLOOD pressure, HEMOGLOBINS, AGE distribution, RETROSPECTIVE studies, PROGNOSIS, SEVERITY of illness index, HEART atrium, PROSTHETIC heart valves, LONGITUDINAL method, BILIRUBIN
Abstract

Objectives: Although the incidence of patients with isolated tricuspid regurgitation (TR) is increasing, data regarding the clinical outcomes of isolated TR surgery are limited. This study sought to investigate the prognostic implications according to procedural types, and to identify preoperative predictors of clinical outcomes after isolated TR surgery.Methods: Among consecutive 2610 patients receiving tricuspid valve (TV) procedure, we analysed 238 patients (age, 59.6 years; 143 females) who underwent stand-alone TV surgery (repair, 132; replacement, 106) for severe TR. Primary outcome was the composite of all-cause mortality and heart transplantation. Clinical outcomes between the repair and the replacement groups were compared after adjusting with the inverse probability of treatment weighting (IPTW) method.Results: During follow-up (median, 4.1 years), 53 patients died and 4 received heart transplantation. Multivariable analysis revealed that age (p=0.001), haemoglobin level (p=0.003), total bilirubin (p=0.040), TR jet area (p=0.005) and right atrial (RA) pressure (p=0.022) were independent predictors of the primary outcome. After IPTW adjustment, there were no significant intergroup differences in the risk of primary outcome (HR 1.01; 95% CI 0.55 to 1.87). In the subgroup analysis, tricuspid annular diameter was identified as a significant effect modifier (p=0.012) in the comparison between repair versus replacement, showing a trend favouring replacement in patients with annular diameter >44 mm.Conclusions: The outcomes of stand-alone severe TR surgery were independently associated with the severity of TR and RA pressure. In selected patients with severe annular dilation >44 mm, replacement may become a feasible option. [ABSTRACT FROM AUTHOR]

Published
2021
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146. Clinicopathological characteristics of primary central nervous system lymphoma with low 18F-fludeoxyglucose uptake on brain positron emission tomography.

Author

Hye Ok Kim, Jae Seung Kim, Seon-Ok Kim, Sun Young Chae, Seung Jun Oh, Minjung Seo, Suk Hyun Lee, Oh, Jungsu S., Jin-Sook Ryu, Joo-Ryung Huh, Jeong Hoon Kim, Kim, Hye Ok, Kim, Jae Seung, Kim, Seon-Ok, Chae, Sun Young, Oh, Seung Jun, Seo, Minjung, Lee, Suk Hyun, Ryu, Jin-Sook, and Huh, Joo-Ryung

Published
2020
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147. Incidence and risk factors of Pneumocystis jirovecii pneumonia in Korean patients with inflammatory bowel disease.

Author

Nam, Kwangwoo, Park, Sang Hyoung, Lee, Junghwan, Jo, Seokjung, Kim, Seon‐Ok, Noh, Soomin, Park, Jae Cheol, Kim, Jin Yong, Kim, Jeongseok, Ham, Nam Seok, Oh, Eun Hye, Song, Eun Mi, Hwang, Sung Wook, Yang, Dong‐Hoon, Ye, Byong Duk, Byeon, Jeong‐Sik, Myung, Seung‐Jae, and Yang, Suk‐Kyun

Subjects
INFLAMMATORY bowel diseases, PNEUMOCYSTIS pneumonia, CROHN'S disease, ULCERATIVE colitis, C-reactive protein
Abstract

Background and Aim: Little is known whether routine prophylaxis against Pneumocystis jirovecii pneumonia (PJP) is needed in patients with inflammatory bowel disease (IBD) on immunosuppression, especially in Asian populations. We, therefore, sought to investigate the incidence and risk factors of PJP in patients with IBD in Korea. Methods: We investigated the incidence of PJP in patients with IBD and compared the characteristics of IBD patients with PJP episodes (IBD‐PJP group) with those of matched controls (IBD‐only group) using a large, well‐characterized referral center‐based cohort. Results: Among the 6803 IBD patients (3171 with Crohn's disease and 3632 with ulcerative colitis) enrolled in the Asan IBD Registry between June 1989 and December 2016, six patients (0.09%) were diagnosed with PJP. During the 57 776.0 patient‐years of follow‐up (median 7.2 years per patient), the incidence of PJP was 10.4 cases per 100 000 person‐years, and none of these patients had received PJP prophylaxis. In case–control analysis, the IBD‐PJP group (n = 6) showed significantly higher C‐reactive protein level at diagnosis of IBD (P = 0.006), as well as higher exposure to corticosteroids (P = 0.017), than did controls (n = 24). In addition, the IBD‐PJP group showed higher rates of double (50% vs 12.5%) or triple (33.3% vs 4.2%) immunosuppression than did controls, although these are not statistically significant. Conclusions: Although the incidence of PJP in Korean patients with IBD is low, careful monitoring is necessary for the early detection of PJP. In addition to the patients receiving double or triple immunosuppression, PJP prophylaxis should be considered especially in patients with severe disease activities requiring corticosteroids. [ABSTRACT FROM AUTHOR]

Published
2020
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150. 171 EUS-GUIDED TRANSMURAL STENTING VS. CONVENTIONAL ERCP ASSISTED TRANSPAPILLARY STENTING FOR PRIMARY PALLIATION OF MALIGNANT DISTAL BILIARY OBSTRUCTION: A RANDOMIZED CLINICAL TRIAL

Author

Paik, Woo Hyun, primary, Lee, Tae Hoon, additional, Park, Do Hyun, additional, Choi, Jun-Ho, additional, Kim, Seon-Ok, additional, Jang, Sunguk, additional, Kim, Dong Uk, additional, Shim, Ju Hyun, additional, Song, Tae Jun, additional, Lee, Sang Soo, additional, Seo, Dong Wan, additional, Lee, Sung Koo, additional, and Kim, Myung-Hwan, additional

Published
2018
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