Search

Your search keyword '"Khazaie, Habibolah"' showing total 824 results
Start Over Author "Khazaie, Habibolah"
824 results on '"Khazaie, Habibolah"'

101. Lack of Structural Brain Alterations associated with Insomnia: Findings from the ENIGMA-Sleep working group

Author

Weihs, Antoine, primary, Frenzel, Stefan, additional, Bi, Hanwen, additional, Schiel, Julian, additional, Afshani, Mortaza, additional, Bülow, Robin, additional, Ewert, Ralf, additional, Fietze, Ingo, additional, Hoffstaedter, Felix, additional, Jahanshad, Neda, additional, Khazaie, Habibolah, additional, Riemann, Dieter, additional, Rostampour, Masoumeh, additional, Stubbe, Beate, additional, Thomopoulos, Sophia, additional, Thompson, Paul, additional, Valk, Sofie, additional, Völzke, Henry, additional, Zarei, Mojtaba, additional, Eickhoff, Simon, additional, Grabe, Hans, additional, Patil, Kaustubh, additional, Spiegelhalder, Kai, additional, and Tahmasian, Masoud, additional

Published
2022
Full Text
View/download PDF

105. Interleukin ‐1α and tumor necrosis factor α as an inducer for reactive‐oxygen‐species‐mediated NOD‐like receptor protein 1/NOD‐like receptor protein 3 inflammasome activation in mononuclear blood cells from individuals with chronic insomnia disorder

Author

Aghelan, Zahra, primary, Karima, Saeed, additional, Khazaie, Habibolah, additional, Abtahi, Seyed Hosein, additional, Farokhi, Ali Reza, additional, Rostampour, Masoumeh, additional, Bahrehmand, Fariborz, additional, and Khodarahmi, Reza, additional

Published
2022
Full Text
View/download PDF

107. Internet Addiction Status and Related Factors among Medical Students: A Cross-Sectional Study in Western Iran.

Author

Khazaie, Habibolah, Lebni, Javad Yoosefi, Abbas, Jaffar, Mahaki, Behzad, Chaboksavar, Fakhreddin, Kianipour, Neda, Toghroli, Razie, and Ziapour, Arash

Subjects
PSYCHOLOGY of medical students, ANALYSIS of variance, DENTAL students, HEALTH occupations students, RESEARCH methodology, HEALTH status indicators, PHARMACISTS, SURVEYS, T-test (Statistics), QUESTIONNAIRES, DESCRIPTIVE statistics, INTERNET addiction, STATISTICAL sampling, DATA analysis software, PSYCHOSOCIAL factors
Abstract

Background: In recent years, Internet and social media technology use have emerged as an integral tool of human society, and the evolution of technological integration, cyberspace, and web-technology has become a common practice in educational institutions. Internet usage among students has played an indispensable role in learning behavior; however, the excessive usage of the internet and social media leads to internet addiction. This original study has performed a focalized scrutiny on revealing relationships between internet addiction and associated factors among the students of medicine, dentistry, and pharmaceutical departments. Methods: This descriptive and analytical study recruited medical students from the Self-governing Education Incubator of Kermanshah. This survey distributed questionnaires among the respondents' three departments, and this statistical data reported on 420 valid responses of the respondents. They represent first and second-semester medical students of the academic year 2017–2018. The study selected medical students by applying Cochran's Sample Size Formula through Stratified Random Sampling and cross-sectional research design. The survey has utilized a demographic questionnaire of Young's Internet Addiction Test (IAT) for the data collection. The study analyzed received data by using SPSS version 23 and performed the descriptive statistics, and analytical statistics (t-test and ANOVA). Results: The results of the present study established that the majority of subjects were female students (53.3%), and the average age was 23.84 ± 2.14, including the students of all departments. Besides, findings specified that the overall mean and standard deviation scores were 3.34 and ±0.88. Internet addiction revealed mean and the standard deviation score measured for all students 3.29 ± 0.73, 3.17 ± 0.92, and 3.57 ± 0.64 correspondingly. The survey results illustrated that medical students' internet addiction substantially correlated with demographic variables, such as age, marital status, the field of study, academic term, significant time of consuming the internet, the key reason of utilizing the internet, and daily usage of the internet (p <.05). Conclusion: The results of the study specified that 25% of medical students showed internet addiction. The students are increasingly using the internet, and it has penetrated among students. The design and implementation of adequate educational programs and the application of internet-based efficiency interventions are essential for both knowledge acquisition and medical students' healthy behavior. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

114. Additional file 1 of High-density lipoprotein cholesterol efflux capacity in patients with obstructive sleep apnea and its relation with disease severity

Author

Fadaei, Reza, Mohassel Azadi, Samaneh, Rhéaume, Eric, and Khazaie, Habibolah

Abstract

Additional file 1: S Figure 1. Cholesterol efflux capacities according to sex. a) Total, b) non-ABCA1, and c) ABCA1 CEC displayed no statistically remarkable difference between females and males in the whole population. d) Total CEC, e) Non-ABCA1 CEC, and f) ABCA1 CEC indicated no remarkable difference in males compared to females in both OSA patients and controls.

Published
2022
Full Text
View/download PDF

115. Additional file 2 of High-density lipoprotein cholesterol efflux capacity in patients with obstructive sleep apnea and its relation with disease severity

Author

Fadaei, Reza, Mohassel Azadi, Samaneh, Rhéaume, Eric, and Khazaie, Habibolah

Abstract

Additional file 2: S Figure 2. Cholesterol efflux capacities according to BMI categories. a) Total, b) Non-ABCA1, and c) ABCA1 CEC have shown no considerable change between normal weight (BMI < 25) and overweight (BMI > 25) in the whole population. d) Total CEC, e) Non-ABCA1 CEC, and f) ABCA1 CEC demonstrated no change in normal weight (BMI < 25) compared with overweight (BMI > 25) in both OSA patients and controls.

Published
2022
Full Text
View/download PDF

126. Increased Levels of ANGPTL3 and CTRP9 in Patients With Obstructive Sleep Apnea and Their Relation to Insulin Resistance and Lipid Metabolism and Markers of Endothelial Dysfunction.

Author

Fadaei, Reza, Azadi, Samaneh Mohassel, Laher, Ismail, and Khazaie, Habibolah

Subjects
BIOMARKERS, ADIPOKINES, LIPOPROTEINS, ENDOTHELIUM, COMPLEMENT (Immunology), LEPTIN, GENETIC disorders, HYPERLIPIDEMIA, SLEEP apnea syndromes, CELL adhesion molecules, ENZYME-linked immunosorbent assay, RESEARCH funding, ADIPONECTIN, LIPID metabolism disorders, VASCULAR endothelial growth factors, BODY mass index, INSULIN resistance, DISEASE complications
Abstract

Objective Obstructive sleep apnea (OSA) has a close relation with obesity and perturbation in adipokines and hepatokines, which are linked to OSA consequences such as insulin resistance, dyslipidemia, and endothelial dysfunction. This study aimed to assess the relation of C1q/TNF-related protein 9 (CTRP9) and angiopoietin-like protein 3 (ANGPTL3) with OSA and biochemical measurements. Methods Serum levels of ANGPTL3, CTRP9, adiponectin, leptin, intercellular adhesion molecule 1 (ICAM-1), and vascular cell adhesion protein 1 (VCAM-1) were determined in 74 OSA patients and 27 controls using enzyme-linked immunosorbent assay kits. Results Levels of ANGPTL3, CTRP9, leptin, ICAM-1, and VCAM-1 were increased in the patients compared to the controls, whereas adiponectin levels decreased. ANGPTL3 had a positive correlation with total cholesterol, triglyceride, low-density lipoprotein cholesterol, ICAM-1, and VCAM-1 and was inversely correlated with leptin. CTRP9 showed a positive correlation with body mass index, insulin resistance, ICAM-1, and VCAM-1. Conclusion The results indicated the relation of ANGLTP3 and CTRP9 with OSA and its complications, which suggested a possible role for these factors in the consequences of OSA. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

132. The Psychometric Properties of the Persian Versions of the Patient Health Questionnaires 9 and 2 as Screening Tools for Detecting Depression among University Students.

Author

Mohamadian, Rasoul, Khazaie, Habibolah, Ahmadi, Seyed Mojtaba, Fatmizade, Mehdi, Ghahremani, Susan, Sadeghi, Hossein, Ansari, Zohreh, Ahmadi, Ahmadreza, and Zare, Sadighe

Subjects
*PSYCHOMETRICS, *MEDICAL screening, *COLLEGE students, *PEARSON correlation (Statistics), *CONFIRMATORY factor analysis
Abstract

Background: Among the common mental disorders in societies, depression is one of the most common mental disorders that affects all groups and classes of society. Students are among the groups with the highest rates of depression. Therefore, the need for a short and effective tool for screening and early detection of depression is felt. The aim of this research is to determine validity, reliability and the best cut-off point of the patient health questionnaires-9 (PHQ-9) and patient health questionnaires-2 (PHQ-2) in university students. Methods: This cross-sectional study was conducted on 246 students of Kermanshah University of medical science in Kermanshah province of Iran. They completed the PHQ-2, PHQ-9, and the Beck Depression Inventory-II (BDI-II). A structured interview was used to diagnose depression. To analyze the data, Cronbach's alpha for internal consistency, the intra-class correlation (ICC) for test-retest reliability, confirmatory factor analysis for construct validity, Pearson Correlation for Convergent validity, and receiver-operating characteristic (ROC) curve for Criterion validity was used. Results: The mean age of the participants was 20.43 ± 2.29. Cronbach's alpha coefficient for PHQ-9 and PHQ-2 was 0.82 and 0.80, respectively. The test-retest reliability based on intra-class correlation (ICC) for PHQ-9 and PHQ-2 after two weeks was 0.81 and 0.73, respectively (P < 0.001). The correlation coefficient between the PHQ-9 and PHQ-2 with the BDI-II was 0.74 and 0.64, respectively (P < 0.001). Confirmatory factor analysis showed that two-factor model and one factor model had good model fit. The best cut-off point score for the PHQ-9 was 10 with a sensitivity of 0.90 and specificity of 0.93, and the best cut-off point score for the PHQ-2 was 3 with the sensitivity of 0.71 and specificity of 0.92. Conclusions: The PHQ-9 and PHQ-2 are suitable tools to screen depression in the university students in Iran. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

135. Androgen regulated protein and pyruvate dehydrogenase kinase 4 in severe erectile dysfunction: A gene expression analysis, and computational study of protein structure

Author

Kazemi, Elham, primary, Zargooshi, Javaad, additional, Dehpahni, Mozhgan Fatahi, additional, Mohammadi Motlagh, Hamid-Reza, additional, Kaboudi, Marzieh, additional, Kahrizi, Danial, additional, Khazaie, Habibolah, additional, Mahaki, Behzad, additional, Mohammadian, Youkhabeh, additional, and Yazdani, Leila, additional

Published
2021
Full Text
View/download PDF

139. Associations between morning salivary cortisol and blood cortisol in individuals with Obstructive Sleep Apnea Syndrome: A meta-analysis

Author

Imani, Mohammad Moslem, Sadeghi, Masoud, Khazaie, Habibolah, Sanjabi, Arezoo, Brand, Serge, Brühl, Annette, and Sadeghi Bahmani, Dena

Abstract

Background: Obstructive sleep apnea syndrome (OSAS) may be associated with an increase in hypothalamic-pituitary-adrenocortical axis activity (HPA AA). We reviewed research comparing morning salivary and blood (serum and plasma) cortisol concentrations of individuals with OSAS to those of healthy controls. Methods: We made a systematic search without any restrictions of the PubMed/Medline, Scopus, Cochrane Library, and Web of Science databases for relevant articles published up to August 25, 2019. Results: Sixteen studies were analyzed in this meta-analysis; five studies compared morning salivary concentrations, five compared serum concentrations, four compared plasma cortisol concentrations, and two compared both salivary and plasma concentrations. In pediatric samples, compared to healthy controls, those with OSAS had significantly lower saliva morning cortisol concentrations (MD = -0.13 µg/dl; 95% CI: 0.21, -0.04; P = 0.003). In contrast, no significant differences were observed for serum cortisol concentrations, plasma cortisol concentrations, or salivary morning cortisol concentrations between adults with and without OSAS (p = 0.61, p = 0.17, p = 0.17). Conclusion: Cortisol concentrations did not differ between adults with OSAS and healthy controls. In contrast, morning salivary cortisol concentrations were lower in children with OSAS, compared to healthy controls. Given that a reduced HPA AA is observed among individuals with chronic stress, it is conceivable that children with OSAS are experiencing chronic psychophysiological stress.

Published
2021
Full Text
View/download PDF

140. Associations Between Morning Salivary and Blood Cortisol Concentrations in Individuals With Obstructive Sleep Apnea Syndrome: A Meta-Analysis

Author

Imani, Mohammad Moslem, Sadeghi, Masoud, Khazaie, Habibolah, Sanjabi, Arezoo, Brand, Serge, Brühl, Annette, and Sadeghi Bahmani, Dena

Subjects
saliva, Sleep Apnea, Obstructive, Hydrocortisone, obstructive sleep apnea syndrome, cortisol, Circadian Rhythm, meta-analysis, Endocrinology, Humans, Systematic Review, sleep, pediatric and adult individuals, serum, plasma, Biomarkers
Abstract

Background Obstructive sleep apnea syndrome (OSAS) may be associated with an increase in hypothalamic-pituitary-adrenocortical axis activity (HPA AA). We reviewed research comparing morning salivary and blood (serum and plasma) cortisol concentrations of individuals with OSAS to those of healthy controls. Methods We made a systematic search without any restrictions of the PubMed/Medline, Scopus, Cochrane Library, and Web of Science databases for relevant articles published up to August 25, 2019. Results Sixteen studies were analyzed in this meta-analysis; five studies compared morning salivary concentrations, five compared serum concentrations, four compared plasma cortisol concentrations, and two compared both salivary and plasma concentrations. In pediatric samples, compared to healthy controls, those with OSAS had significantly lower saliva morning cortisol concentrations (MD = -0.13 µg/dl; 95% CI: 0.21, -0.04; P = 0.003). In contrast, no significant differences were observed for serum cortisol concentrations, plasma cortisol concentrations, or salivary morning cortisol concentrations between adults with and without OSAS (p = 0.61, p = 0.17, p = 0.17). Conclusion Cortisol concentrations did not differ between adults with OSAS and healthy controls. In contrast, morning salivary cortisol concentrations were lower in children with OSAS, compared to healthy controls. Given that a reduced HPA AA is observed among individuals with chronic stress, it is conceivable that children with OSAS are experiencing chronic psychophysiological stress.

Published
2021

141. ENIGMA-Sleep: Challenges, opportunities, and the road map

Author

Tahmasian, Masoud, Aleman, André, Andreassen, Ole A, Arab, Zahra, Baillet, Marion, Benedetti, Francesco, Bresser, Tom, Bright, Joanna, Chee, Michael W L, Chylinski, Daphne, Cheng, Wei, Deantoni, Michele, Dresler, Martin, Eickhoff, Simon B, Eickhoff, Claudia R, Elvsåshagen, Torbjørn, Feng, Jianfeng, Foster-Dingley, Jessica C, Ganjgahi, Habib, Grabe, Hans J, Groenewold, Nynke A, Ho, Tiffany C, Bong Hong, Seung, Houenou, Josselin, Irungu, Benson, Jahanshad, Neda, Khazaie, Habibolah, Kim, Hosung, Koshmanova, Ekaterina, Kocevska, Desi, Kochunov, Peter, Lakbila-Kamal, Oti, Leerssen, Jeanne, Li, Meng, Luik, Annemarie I, Muto, Vincenzo, Narbutas, Justinas, Nilsonne, Gustav, O'Callaghan, Victoria S, Olsen, Alexander, Osorio, Ricardo S, Poletti, Sara, Poudel, Govinda, Reesen, Joyce E, Reneman, Liesbeth, Reyt, Mathilde, Riemann, Dieter, Rosenzweig, Ivana, Rostampour, Masoumeh, Saberi, Amin, Schiel, Julian, Schmidt, Christina, Schrantee, Anouk, Sciberras, Emma, Silk, Tim J, Sim, Kang, Smevik, Hanne, Soares, Jair C, Spiegelhalder, Kai, Stein, Dan J, Talwar, Puneet, Tamm, Sandra, Teresi, Giana L, Valk, Sofie L, Van Someren, Eus, Vandewalle, Gilles, Van Egroo, Maxime, Völzke, Henry, Walter, Martin, Wassing, Rick, Weber, Frederik D, Weihs, Antoine, Westlye, Lars Tjelta, Wright, Margaret J, Wu, Mon-Ju, Zak, Nathalia, Zarei, Mojtaba, Tahmasian, Masoud, Aleman, André, Andreassen, Ole A, Arab, Zahra, Baillet, Marion, Benedetti, Francesco, Bresser, Tom, Bright, Joanna, Chee, Michael W L, Chylinski, Daphne, Cheng, Wei, Deantoni, Michele, Dresler, Martin, Eickhoff, Simon B, Eickhoff, Claudia R, Elvsåshagen, Torbjørn, Feng, Jianfeng, Foster-Dingley, Jessica C, Ganjgahi, Habib, Grabe, Hans J, Groenewold, Nynke A, Ho, Tiffany C, Bong Hong, Seung, Houenou, Josselin, Irungu, Benson, Jahanshad, Neda, Khazaie, Habibolah, Kim, Hosung, Koshmanova, Ekaterina, Kocevska, Desi, Kochunov, Peter, Lakbila-Kamal, Oti, Leerssen, Jeanne, Li, Meng, Luik, Annemarie I, Muto, Vincenzo, Narbutas, Justinas, Nilsonne, Gustav, O'Callaghan, Victoria S, Olsen, Alexander, Osorio, Ricardo S, Poletti, Sara, Poudel, Govinda, Reesen, Joyce E, Reneman, Liesbeth, Reyt, Mathilde, Riemann, Dieter, Rosenzweig, Ivana, Rostampour, Masoumeh, Saberi, Amin, Schiel, Julian, Schmidt, Christina, Schrantee, Anouk, Sciberras, Emma, Silk, Tim J, Sim, Kang, Smevik, Hanne, Soares, Jair C, Spiegelhalder, Kai, Stein, Dan J, Talwar, Puneet, Tamm, Sandra, Teresi, Giana L, Valk, Sofie L, Van Someren, Eus, Vandewalle, Gilles, Van Egroo, Maxime, Völzke, Henry, Walter, Martin, Wassing, Rick, Weber, Frederik D, Weihs, Antoine, Westlye, Lars Tjelta, Wright, Margaret J, Wu, Mon-Ju, Zak, Nathalia, and Zarei, Mojtaba

Abstract

Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine.

Published
2021

142. When Non-Suicidal Self-Injury Predicts Non-Suicidal Self-Injury and Poor Sleep—Results from a Larger Cross-Sectional and Quasi-Longitudinal Study

Author

Khazaie, Habibolah; https://orcid.org/0000-0003-1720-3720, Khazaie, Sepideh, Zakiei, Ali; https://orcid.org/0000-0002-5259-6104, Dürsteler, Kenneth M; https://orcid.org/0000-0003-1552-5822, Brühl, Annette Beatrix; https://orcid.org/0000-0003-4704-4986, Brand, Serge; https://orcid.org/0000-0003-2175-2765, Sadeghi-Bahmani, Dena, Khazaie, Habibolah; https://orcid.org/0000-0003-1720-3720, Khazaie, Sepideh, Zakiei, Ali; https://orcid.org/0000-0002-5259-6104, Dürsteler, Kenneth M; https://orcid.org/0000-0003-1552-5822, Brühl, Annette Beatrix; https://orcid.org/0000-0003-4704-4986, Brand, Serge; https://orcid.org/0000-0003-2175-2765, and Sadeghi-Bahmani, Dena

Abstract

Poor sleep is associated with a higher risk of non-suicidal self-injury (NSSI) as a proxy of unfavorable emotion regulation. In the present study, we tested the hypothesis that past non-suicidal self-injury was associated with current non-suicidal self-injury and with current subjective sleep patterns. To this end, a larger sample of young adults were assessed. A total of 2374 adults (mean age: 27.58 years; 39.6% females) completed a series of self-rating questionnaires covering sociodemographic information, past and current NSSIs, suicide attempts, and current sleep patterns, including experiencing nightmares. Past NSSIs predicted current NSSIs. Current sleep patterns had a modest impact on the association between past and current NSSIs. Compared to male participants, female participants did not report more sleep complaints or more current NSSIs, but more past NSSIs. Past NSSIs predicted the occurrences of nightmares and suicide attempts. The best predictor of current NSSI was the remembered past NSSI, while current poor sleep was only modestly associated with current NSSI. Further indicators of current NSSI and poor sleep were suicide attempts and nightmares within the last six months. Overall, it appears that poor emotion regulation should be considered as underlying factor to trigger and maintain non-suicidal self-injury-related behavior and poor sleep. Further, unlike previous studies, which focused on the possible influence of sleep patterns on NSSIs, the aim of the present study paradigm was to investigate NSSIs on sleep patterns.

Published
2021

143. Acceptance and Commitment Therapy (ACT) Improves Sleep Quality, Experiential Avoidance, and Emotion Regulation in Individuals with Insomnia-Results from a Randomized Interventional Study

Author

Zakiei, Ali; https://orcid.org/0000-0002-5259-6104, Khazaie, Habibolah; https://orcid.org/0000-0003-1720-3720, Rostampour, Masoumeh, Lemola, Sakari; https://orcid.org/0000-0002-1314-6194, Esmaeili, Maryam, Dürsteler, Kenneth, Brühl, Annette Beatrix; https://orcid.org/0000-0003-4704-4986, Sadeghi-Bahmani, Dena; https://orcid.org/0000-0002-1301-5522, Brand, Serge; https://orcid.org/0000-0003-2175-2765, Zakiei, Ali; https://orcid.org/0000-0002-5259-6104, Khazaie, Habibolah; https://orcid.org/0000-0003-1720-3720, Rostampour, Masoumeh, Lemola, Sakari; https://orcid.org/0000-0002-1314-6194, Esmaeili, Maryam, Dürsteler, Kenneth, Brühl, Annette Beatrix; https://orcid.org/0000-0003-4704-4986, Sadeghi-Bahmani, Dena; https://orcid.org/0000-0002-1301-5522, and Brand, Serge; https://orcid.org/0000-0003-2175-2765

Abstract

Insomnia is a common problem in the general population. To treat insomnia, medication therapies and insomnia-related cognitive-behavioral interventions are often applied. The aim of the present study was to investigate the influence of acceptance and commitment therapy (ACT) on sleep quality, dysfunctional sleep beliefs and attitudes, experiential avoidance, and acceptance of sleep problems in individuals with insomnia, compared to a control condition. A total of 35 participants with diagnosed insomnia (mean age: 41.46 years old; 62.9% females) were randomly assigned to the ACT intervention (weekly group therapy for 60-70 min) or to the active control condition (weekly group meetings for 60-70 min without interventional and psychotherapeutic character). At baseline and after eight weeks (end of the study), and again 12 weeks later at follow-up, participants completed self-rating questionnaires on sleep quality, dysfunctional beliefs and attitudes about sleep, emotion regulation, and experiential avoidance. Furthermore, participants in the intervention condition kept a weekly sleep log for eight consecutive weeks (micro-analysis). Every morning, participants completed the daily sleep log, which consisted of items regarding subjective sleep duration, sleep quality, and the feeling of being restored. Sleep quality, dysfunctional beliefs and attitudes towards sleep, emotion regulation, and experiential avoidance improved over time, but only in the ACT condition compared to the control condition. Improvements remained stable until follow-up. Improvements in experiential avoidance were related to a favorable change in sleep and cognitive-emotional processing. Micro-analyses showed that improvements occurred within the first three weeks of treatment. The pattern of results suggests that ACT appeared to have improved experiential avoidance, which in turn improved both sleep quality and sleep-related cognitive-emotional processes at longer-term in adults with insomnia. Keywo

Published
2021

144. Evaluation of Blood Levels of C-Reactive Protein Marker in Obstructive Sleep Apnea: A Systematic Review, Meta‐Analysis and Meta-Regression

Author

Imani, Mohammad Moslem, Sadeghi, Masoud, Farokhzadeh, Farid, Khazaie, Habibolah, Brand, Serge; https://orcid.org/0000-0003-2175-2765, Dürsteler, Kenneth M, Brühl, Annette; https://orcid.org/0000-0003-4704-4986, Sadeghi-Bahmani, Dena; https://orcid.org/0000-0002-1301-5522, Imani, Mohammad Moslem, Sadeghi, Masoud, Farokhzadeh, Farid, Khazaie, Habibolah, Brand, Serge; https://orcid.org/0000-0003-2175-2765, Dürsteler, Kenneth M, Brühl, Annette; https://orcid.org/0000-0003-4704-4986, and Sadeghi-Bahmani, Dena; https://orcid.org/0000-0002-1301-5522

Abstract

(1) Introduction: High sensitivity C-reactive protein (hs-CRP) and CRP are inflammatory biomarkers associated with several inflammatory diseases. In both pediatric and adult individuals with Obstructive Sleep Apnea (OSA) higher hs-CRP and CRP were observed, compared to controls. With the present systematic review, meta-analysis and meta-regression we expand upon previous meta-analyses in four ways: (1) We included 109 studies (96 in adults and 13 in children); (2) we reported subgroup and meta-regression analyses in adults with OSA compared to controls on the serum and plasma levels of hs-CRP; (3) we reported subgroup and meta-regression analyses in adults with OSA compared to controls on the serum and plasma levels of CRP; (4) we reported serum and plasma levels of both hs-CRP and CRP in children with OSA, always compared to controls. (2) Materials and Methods: The PubMed/Medline, Scopus, Cochrane Library, and Web of Science databases were searched to retrieve articles published until 31 May 2020, with no restrictions. The data included basic information involving the first author, publication year, country of study, ethnicity of participants in each study, age, BMI, and AHI of both groups, and mean and standard deviation (SD) of plasma and serum levels of CRP and hs-CRP. (3) Results: A total of 1046 records were retrieved from the databases, and 109 studies were selected for the analysis (96 studies reporting the blood levels of hs-CRP/CRP in adults and 13 studies in children). For adults, 11 studies reported plasma hs-CRP, 44 serum hs-CRP, 9 plasma CRP, and 32 serum CRP levels. For children, 6 studies reported plasma hs-CRP, 4 serum hs-CRP, 1 plasma CRP, and 2 serum CRP levels. Compared to controls, the pooled MD of plasma hs-CRP levels in adults with OSA was 0.11 mg/dL (p < 0.00001). Compared to controls, the pooled MD of serum hs-CRP levels in adults with OSA was 0.09 mg/dL (p < 0.00001). Compared to controls, the pooled MD of plasma CRP levels in adults with O

Published
2021

149. ENIGMA‐Sleep: Challenges, opportunities, and the road map

Author

Tahmasian, Masoud, primary, Aleman, André, additional, Andreassen, Ole A., additional, Arab, Zahra, additional, Baillet, Marion, additional, Benedetti, Francesco, additional, Bresser, Tom, additional, Bright, Joanna, additional, Chee, Michael W.L., additional, Chylinski, Daphne, additional, Cheng, Wei, additional, Deantoni, Michele, additional, Dresler, Martin, additional, Eickhoff, Simon B., additional, Eickhoff, Claudia R., additional, Elvsåshagen, Torbjørn, additional, Feng, Jianfeng, additional, Foster‐Dingley, Jessica C., additional, Ganjgahi, Habib, additional, Grabe, Hans J., additional, Groenewold, Nynke A., additional, Ho, Tiffany C., additional, Bong Hong, Seung, additional, Houenou, Josselin, additional, Irungu, Benson, additional, Jahanshad, Neda, additional, Khazaie, Habibolah, additional, Kim, Hosung, additional, Koshmanova, Ekaterina, additional, Kocevska, Desi, additional, Kochunov, Peter, additional, Lakbila‐Kamal, Oti, additional, Leerssen, Jeanne, additional, Li, Meng, additional, Luik, Annemarie I., additional, Muto, Vincenzo, additional, Narbutas, Justinas, additional, Nilsonne, Gustav, additional, O’Callaghan, Victoria S., additional, Olsen, Alexander, additional, Osorio, Ricardo S., additional, Poletti, Sara, additional, Poudel, Govinda, additional, Reesen, Joyce E., additional, Reneman, Liesbeth, additional, Reyt, Mathilde, additional, Riemann, Dieter, additional, Rosenzweig, Ivana, additional, Rostampour, Masoumeh, additional, Saberi, Amin, additional, Schiel, Julian, additional, Schmidt, Christina, additional, Schrantee, Anouk, additional, Sciberras, Emma, additional, Silk, Tim J., additional, Sim, Kang, additional, Smevik, Hanne, additional, Soares, Jair C., additional, Spiegelhalder, Kai, additional, Stein, Dan J., additional, Talwar, Puneet, additional, Tamm, Sandra, additional, Teresi, Giana l., additional, Valk, Sofie L., additional, Someren, Eus, additional, Vandewalle, Gilles, additional, Van Egroo, Maxime, additional, Völzke, Henry, additional, Walter, Martin, additional, Wassing, Rick, additional, Weber, Frederik D., additional, Weihs, Antoine, additional, Westlye, Lars Tjelta, additional, Wright, Margaret J., additional, Wu, Mon‐Ju, additional, Zak, Nathalia, additional, and Zarei, Mojtaba, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results