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102. Nb3Sn films on sapphire - a promising alternative for superconductive microwave technology

Author

Perpeet, M., Cassinese, A., Hein, M.A., Kaiser, T., Muller, G., Piel, H., and Pouryamout, J.

Subjects
High temperature superconductors -- Research, Metallic films -- Research, Microwave devices -- Research, Thin films -- Research, Business, Electronics, Electronics and electrical industries
Abstract

A two-step process was used to prepare phase-pure, large-grained Nb3Sn films on sapphire substrates with properties comparable to those of Nb3Sn on Nb. The process used enabled the control of grain size between 0.1 micron and 3.0 microns by varying the film thickness. Close correlations between the transport properties and the degree of granularity were observed. Results are very promising for specific microwave applications requiring very high quality factors and arrow bandwidths that might be difficult to achieve with YBa2Cu3O7-delta.

Published
1999

103. A-doped double-sided PLD - YBCO thin films for passive microwave devices in future communication systems

Author

Lorenz, M., Hochmuth, H., Natusch, D., Lippold, G., Svetchnikov, V.L., Kaiser, T., Hein, M.A., Schwab, R., and Heidinger, R.

Subjects
Communications equipment -- Research, High temperature superconductors -- Research, X-ray diffractometer -- Usage, Yttrium barium copper oxides -- Research, Business, Electronics, Electronics and electrical industries
Abstract

Ag-doped YBa2Cu3O7-x (YBCO) thin films which are pulsed laser deposited in diameter sapphire wafers are regularly used in developing microwave filters for future communication systems. Critical current densities of 4 MA/cm2 at at 77 K and homogeneous maps of microwave surface resistance of about 45 momega at 145 GHz and 77 K are manifested in the reproducibly deposited YBCO:Ag films of about 250 nm thickness.

Published
1999

104. Synthesis and microwave properties of thin films of the 1;2;2:1 borocarbide superconductors YNiBC and ErNiBC

Author

Andreone, A., Aruta, C., Iavarone, M., Palomba, F., Russo, M.L., Salluzzo, M., Vaglio, R., Cassinese, A., Hein, M.A., Kaiser, T., Mueller, G., and Perpeet, M.

Subjects
Magnetrons -- Usage, Sputtering (Physics) -- Usage, Superconductors -- Research, Thin films -- Research, Business, Electronics, Electronics and electrical industries
Abstract

Planar magnetron sputtering was used to grow high-quality c-axis oriented YNi2B2C and ErNi2B2C borocarbide superconducting thin films on MgO, LaAlO3 and sapphire substrates. It was observed that the fabricated YNi2B2C demonstrate a conventional BCS behavior while the deposited ErNi2B2C has an anomalous behavior, which is influenced the Er-sites' magnetic moments. It was also noted that the both samples exhibit a high absolute value and a strong field dependence of the residual losses.

Published
1999

105. Microstructure and microwave surface resistance of YBaCuO thin films

Author

Kastner, G., Schafer, C., Senz, S., Hesse, D., Lorenz, M., Hochmuth, H., Getta, M., Hein, M.A., Kaiser, T., and Muller, G.

Subjects
High temperature superconductivity -- Research, High temperature superconductors -- Research, Thin films -- Research, Yttrium barium copper oxides -- Usage, Business, Electronics, Electronics and electrical industries
Abstract

Characterizations via X-ray diffraction, electron and optical microscopy were conducted on epitaxial YBaCuO thin films intended for microwave applications as a guide for optimizing their attributes. The high temperature superconductor thin films were grown on 50 mm diameter LaAlO3 and 73 mm diameter sapphire wafers. The sapphire substrates presented challenges in microcracking while the LaAlO3 produced films that are sensitive to high microwave power.

Published
1999

106. YBaCuO disk resonator filters operating at high power

Author

Aminov, B.A., Piel, H., Hein, M.A., Kaiser, T., Muller, G., Baumfalk, A., Chaloupka, H.J., Kolesov, S., Medelius, H., and Wikborg, E.

Subjects
Microwave filters -- Design and construction, Thin films -- Electric properties, Business, Electronics, Electronics and electrical industries
Abstract

A compact tunable one-pole filter at 2 GHz was developed and successfully operated for transmitter combiners in mobile radio base stations. The concept was based on edge-current free modes in circular symmetric resonators. The power handling of the filer declined in proportion to the duty cycle which suggests that heating is the dominant limitation. Results show that the CW power handling was not impacted by the tuning but the radiation losses and the maximum achievable power levels were degraded compared to the fixed-frequency filter.

Published
1999

122. Wie werden ausschließlich in Studienregistern veröffentlichte Studien und deren Ergebnisse in aktuellen Cochrane Reviews zu Arzneimitteln berücksichtigt?

Author

Goldkuhle, M, Kaiser, T, and Skoetz, N

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund/Fragestellung: Die Suche in Studienregistern ist ein wichtiges Instrument zur Kontrolle von Publikationsbias und Standard bei der Erstellung von Cochrane Reviews. Es ist jedoch unklar, welchen Stellenwert die Studienregistersuche in Cochrane Reviews hat und wie Reviewautoren mit Studien[zum vollständigen Text gelangen Sie über die oben angegebene URL], EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2019
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124. Cytotoxic CD4+ T cells in viral hepatitis

Author

Aslan, N., Yurdaydin, C., Wiegand, J., Greten, T., Ciner, A., Meyer, M. F., Heiken, H., Kuhlmann, B., Kaiser, T., Bozkaya, H., Tillmann, H. L., Bozdayi, A. M., Manns, M. P., and Wedemeyer, H.

Published
2006

125. Surface resistance and nonlinear dynamic microwave losses of epitaxial HTS films

Author

Diete, W., Getta, M., Hein, M., Kaiser, T., Muller, G., Piel, H., and Schlick, H.

Subjects
High temperature superconductors -- Research, Thin films -- Electric properties, Microwave measurements -- Analysis, Business, Electronics, Electronics and electrical industries
Abstract

A study was conducted on epitaxial high temperature superconductor films' surface resistance and nonlinear microwave losses using a dielectric resonator technique. Maximum surface magnetic fields between 1 and 15mT were obtained at 77 K for YBa2Cu2O7-delta films. The approach permits the identification of defects, heating and intrinsic phenomena and other loss mechanisms.

Published
1997

127. Multicentre reference values for cardiac magnetic resonance imaging derived ventricular size and function for children aged 0-18 years

Author

van der Ven, J.P.G. (J. P.G.), Sadighy, Z. (Z.), Valsangiacomo Buechel, E.R., Sarikouch, S., Robbers-Visser, D. (Daniëlle), Kellenberger, C.J. (C. J.), Kaiser, T. (T.), Beerbaum, P., Boersma, H. (Eric), Helbing, W.A. (Willem), van der Ven, J.P.G. (J. P.G.), Sadighy, Z. (Z.), Valsangiacomo Buechel, E.R., Sarikouch, S., Robbers-Visser, D. (Daniëlle), Kellenberger, C.J. (C. J.), Kaiser, T. (T.), Beerbaum, P., Boersma, H. (Eric), and Helbing, W.A. (Willem)

Abstract

AIMS: Cardiovascular magnetic resonance (CMR) imaging is an important tool in the assessment of paediatric cardiac disease. Reported reference values of ventricular volumes and masses in the paediatric population are based on small cohorts and several methodologic differences between studies exist. We sought to create steady-state free precession (SSFP) CMR reference values for biventricular volumes and mass by combining data of previously published studies and re-analysing these data in a standardized manner. METHODS AND RESULTS: A total of 141 healthy children (68 boys) from three European centres underwent cine-SSFP CMR imaging. Cardiac structures were manually contoured for end-diastolic and end-systolic phases in the short-axis orientation according to current standardized CMR post-processing guidelines. Volumes and masses were derived from these contours. Age-related reference curves were constructed using the lambda mu sigma method. Median age was 12.7 years (range 0.6-18.5). We report biventricular volumes and masses, unindexed and indexed for body surface area, stratified by age groups. In general, boys had approximately 15% higher biventricular volumes and masses compared with girls. Only in children aged <6 years old no gender differences could be observed. Left ventricle ejection fraction was slightly higher in boys in this study population (median 67% vs. 65%, P = 0.016). Age-related reference curves showed non-linear relations between age and cardiac parameters. CONCLUSION: We report volumetric SSFP CMR imaging reference values for children aged 0-18 years old in a relatively large multi-centre cohort. These references can be used in the follow-up of paedia

Published
2019
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128. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Author

Cossarizza, A, Chang, H-D, Radbruch, A, Acs, A, Adam, D, Adam-Klages, S, Agace, WW, Aghaeepour, N, Akdis, M, Allez, M, Almeida, LN, Alvisi, G, Anderson, G, Andrae, I, Annunziato, F, Anselmo, A, Bacher, P, Baldari, CT, Bari, S, Barnaba, V, Barros-Martins, J, Battistini, L, Bauer, W, Baumgart, S, Baumgarth, N, Baumjohann, D, Baying, B, Bebawy, M, Becher, B, Beisker, W, Benes, V, Beyaert, R, Blanco, A, Boardman, DA, Bogdan, C, Borger, JG, Borsellino, G, Boulais, PE, Bradford, JA, Brenner, D, Brinkman, RR, Brooks, AES, Busch, DH, Buescher, M, Bushnell, TP, Calzetti, F, Cameron, G, Cammarata, I, Cao, X, Cardell, SL, Casola, S, Cassatella, MA, Cavani, A, Celada, A, Chatenoud, L, Chattopadhyay, PK, Chow, S, Christakou, E, Cicin-Sain, L, Clerici, M, Colombo, FS, Cook, L, Cooke, A, Cooper, AM, Corbett, AJ, Cosma, A, Cosmi, L, Coulie, PG, Cumano, A, Cvetkovic, L, Dang, VD, Dang-Heine, C, Davey, MS, Davies, D, De Biasi, S, Del Zotto, G, Dela Cruz, GV, Delacher, M, Della Bella, S, Dellabona, P, Deniz, G, Dessing, M, Di Santo, JP, Diefenbach, A, Dieli, F, Dolf, A, Doerner, T, Dress, RJ, Dudziak, D, Dustin, M, Dutertre, C-A, Ebner, F, Eckle, SBG, Edinger, M, Eede, P, Ehrhardt, GRA, Eich, M, Engel, P, Engelhardt, B, Erdei, A, Esser, C, Everts, B, Evrard, M, Falk, CS, Fehniger, TA, Felipo-Benavent, M, Ferry, H, Feuerer, M, Filby, A, Filkor, K, Fillatreau, S, Follo, M, Foerster, I, Foster, J, Foulds, GA, Frehse, B, Frenette, PS, Frischbutter, S, Fritzsche, W, Galbraith, DW, Gangaev, A, Garbi, N, Gaudilliere, B, Gazzinelli, RT, Geginat, J, Gerner, W, Gherardin, NA, Ghoreschi, K, Gibellini, L, Ginhoux, F, Goda, K, Godfrey, DI, Goettlinger, C, Gonzalez-Navajas, JM, Goodyear, CS, Gori, A, Grogan, JL, Grummitt, D, Gruetzkau, A, Haftmann, C, Hahn, J, Hammad, H, Haemmerling, G, Hansmann, L, Hansson, G, Harpur, CM, Hartmann, S, Hauser, A, Hauser, AE, Haviland, DL, Hedley, D, Hernandez, DC, Herrera, G, Herrmann, M, Hess, C, Hoefer, T, Hoffmann, P, Hogquist, K, Holland, T, Hollt, T, Holmdahl, R, Hombrink, P, Houston, JP, Hoyer, BF, Huang, B, Huang, F-P, Huber, JE, Huehn, J, Hundemer, M, Hunter, CA, Hwang, WYK, Iannone, A, Ingelfinger, F, Ivison, SM, Jaeck, H-M, Jani, PK, Javega, B, Jonjic, S, Kaiser, T, Kalina, T, Kamradt, T, Kaufmann, SHE, Keller, B, Ketelaars, SLC, Khalilnezhad, A, Khan, S, Kisielow, J, Klenerman, P, Knopf, J, Koay, H-F, Kobow, K, Kolls, JK, Kong, WT, Kopf, M, Korn, T, Kriegsmann, K, Kristyanto, H, Kroneis, T, Krueger, A, Kuehne, J, Kukat, C, Kunkel, D, Kunze-Schumacher, H, Kurosaki, T, Kurts, C, Kvistborg, P, Kwok, I, Landry, J, Lantz, O, Lanuti, P, LaRosa, F, Lehuen, A, LeibundGut-Landmann, S, Leipold, MD, Leung, LYT, Levings, MK, Lino, AC, Liotta, F, Litwin, V, Liu, Y, Ljunggren, H-G, Lohoff, M, Lombardi, G, Lopez, L, Lopez-Botet, M, Lovett-Racke, AE, Lubberts, E, Luche, H, Ludewig, B, Lugli, E, Lunemann, S, Maecker, HT, Maggi, L, Maguire, O, Mair, F, Mair, KH, Mantovani, A, Manz, RA, Marshall, AJ, Martinez-Romero, A, Martrus, G, Marventano, I, Maslinski, W, Matarese, G, Mattioli, AV, Maueroder, C, Mazzoni, A, McCluskey, J, McGrath, M, McGuire, HM, McInnes, IB, Mei, HE, Melchers, F, Melzer, S, Mielenz, D, Miller, SD, Mills, KHG, Minderman, H, Mjosberg, J, Moore, J, Moran, B, Moretta, L, Mosmann, TR, Mueller, S, Multhoff, G, Munoz, LE, Munz, C, Nakayama, T, Nasi, M, Neumann, K, Ng, LG, Niedobitek, A, Nourshargh, S, Nunez, G, O'Connor, J-E, Ochel, A, Oja, A, Ordonez, D, Orfao, A, Orlowski-Oliver, E, Ouyang, W, Oxenius, A, Palankar, R, Panse, I, Pattanapanyasat, K, Paulsen, M, Pavlinic, D, Penter, L, Peterson, P, Peth, C, Petriz, J, Piancone, F, Pickl, WF, Piconese, S, Pinti, M, Pockley, AG, Podolska, MJ, Poon, Z, Pracht, K, Prinz, I, Pucillo, CEM, Quataert, SA, Quatrini, L, Quinn, KM, Radbruch, H, Radstake, TRDJ, Rahmig, S, Rahn, H-P, Rajwa, B, Ravichandran, G, Raz, Y, Rebhahn, JA, Recktenwald, D, Reimer, D, Reis e Sousa, C, Remmerswaal, EBM, Richter, L, Rico, LG, Riddell, A, Rieger, AM, Robinson, JP, Romagnani, C, Rubartelli, A, Ruland, J, Saalmueller, A, Saeys, Y, Saito, T, Sakaguchi, S, Sala-de-Oyanguren, F, Samstag, Y, Sanderson, S, Sandrock, I, Santoni, A, Sanz, RB, Saresella, M, Sautes-Fridman, C, Sawitzki, B, Schadt, L, Scheffold, A, Scherer, HU, Schiemann, M, Schildberg, FA, Schimisky, E, Schlitzer, A, Schlosser, J, Schmid, S, Schmitt, S, Schober, K, Schraivogel, D, Schuh, W, Schueler, T, Schulte, R, Schulz, AR, Schulz, SR, Scotta, C, Scott-Algara, D, Sester, DP, Shankey, TV, Silva-Santos, B, Simon, AK, Sitnik, KM, Sozzani, S, Speiser, DE, Spidlen, J, Stahlberg, A, Stall, AM, Stanley, N, Stark, R, Stehle, C, Steinmetz, T, Stockinger, H, Takahama, Y, Takeda, K, Tan, L, Tarnok, A, Tiegs, G, Toldi, G, Tornack, J, Traggiai, E, Trebak, M, Tree, TIM, Trotter, J, Trowsdale, J, Tsoumakidou, M, Ulrich, H, Urbanczyk, S, van de Veen, W, van den Broek, M, van der Pol, E, Van Gassen, S, Van Isterdael, G, van Lier, RAW, Veldhoen, M, Vento-Asturias, S, Vieira, P, Voehringer, D, Volk, H-D, von Borstel, A, von Volkmann, K, Waisman, A, Walker, RV, Wallace, PK, Wang, SA, Wang, XM, Ward, MD, Ward-Hartstonge, KA, Warnatz, K, Warnes, G, Warth, S, Waskow, C, Watson, JV, Watzl, C, Wegener, L, Weisenburger, T, Wiedemann, A, Wienands, J, Wilharm, A, Wilkinson, RJ, Willimsky, G, Wing, JB, Winkelmann, R, Winkler, TH, Wirz, OF, Wong, A, Wurst, P, Yang, JHM, Yang, J, Yazdanbakhsh, M, Yu, L, Yue, A, Zhang, H, Zhao, Y, Ziegler, SM, Zielinski, C, Zimmermann, J, Zychlinsky, A, Cossarizza, A, Chang, H-D, Radbruch, A, Acs, A, Adam, D, Adam-Klages, S, Agace, WW, Aghaeepour, N, Akdis, M, Allez, M, Almeida, LN, Alvisi, G, Anderson, G, Andrae, I, Annunziato, F, Anselmo, A, Bacher, P, Baldari, CT, Bari, S, Barnaba, V, Barros-Martins, J, Battistini, L, Bauer, W, Baumgart, S, Baumgarth, N, Baumjohann, D, Baying, B, Bebawy, M, Becher, B, Beisker, W, Benes, V, Beyaert, R, Blanco, A, Boardman, DA, Bogdan, C, Borger, JG, Borsellino, G, Boulais, PE, Bradford, JA, Brenner, D, Brinkman, RR, Brooks, AES, Busch, DH, Buescher, M, Bushnell, TP, Calzetti, F, Cameron, G, Cammarata, I, Cao, X, Cardell, SL, Casola, S, Cassatella, MA, Cavani, A, Celada, A, Chatenoud, L, Chattopadhyay, PK, Chow, S, Christakou, E, Cicin-Sain, L, Clerici, M, Colombo, FS, Cook, L, Cooke, A, Cooper, AM, Corbett, AJ, Cosma, A, Cosmi, L, Coulie, PG, Cumano, A, Cvetkovic, L, Dang, VD, Dang-Heine, C, Davey, MS, Davies, D, De Biasi, S, Del Zotto, G, Dela Cruz, GV, Delacher, M, Della Bella, S, Dellabona, P, Deniz, G, Dessing, M, Di Santo, JP, Diefenbach, A, Dieli, F, Dolf, A, Doerner, T, Dress, RJ, Dudziak, D, Dustin, M, Dutertre, C-A, Ebner, F, Eckle, SBG, Edinger, M, Eede, P, Ehrhardt, GRA, Eich, M, Engel, P, Engelhardt, B, Erdei, A, Esser, C, Everts, B, Evrard, M, Falk, CS, Fehniger, TA, Felipo-Benavent, M, Ferry, H, Feuerer, M, Filby, A, Filkor, K, Fillatreau, S, Follo, M, Foerster, I, Foster, J, Foulds, GA, Frehse, B, Frenette, PS, Frischbutter, S, Fritzsche, W, Galbraith, DW, Gangaev, A, Garbi, N, Gaudilliere, B, Gazzinelli, RT, Geginat, J, Gerner, W, Gherardin, NA, Ghoreschi, K, Gibellini, L, Ginhoux, F, Goda, K, Godfrey, DI, Goettlinger, C, Gonzalez-Navajas, JM, Goodyear, CS, Gori, A, Grogan, JL, Grummitt, D, Gruetzkau, A, Haftmann, C, Hahn, J, Hammad, H, Haemmerling, G, Hansmann, L, Hansson, G, Harpur, CM, Hartmann, S, Hauser, A, Hauser, AE, Haviland, DL, Hedley, D, Hernandez, DC, Herrera, G, Herrmann, M, Hess, C, Hoefer, T, Hoffmann, P, Hogquist, K, Holland, T, Hollt, T, Holmdahl, R, Hombrink, P, Houston, JP, Hoyer, BF, Huang, B, Huang, F-P, Huber, JE, Huehn, J, Hundemer, M, Hunter, CA, Hwang, WYK, Iannone, A, Ingelfinger, F, Ivison, SM, Jaeck, H-M, Jani, PK, Javega, B, Jonjic, S, Kaiser, T, Kalina, T, Kamradt, T, Kaufmann, SHE, Keller, B, Ketelaars, SLC, Khalilnezhad, A, Khan, S, Kisielow, J, Klenerman, P, Knopf, J, Koay, H-F, Kobow, K, Kolls, JK, Kong, WT, Kopf, M, Korn, T, Kriegsmann, K, Kristyanto, H, Kroneis, T, Krueger, A, Kuehne, J, Kukat, C, Kunkel, D, Kunze-Schumacher, H, Kurosaki, T, Kurts, C, Kvistborg, P, Kwok, I, Landry, J, Lantz, O, Lanuti, P, LaRosa, F, Lehuen, A, LeibundGut-Landmann, S, Leipold, MD, Leung, LYT, Levings, MK, Lino, AC, Liotta, F, Litwin, V, Liu, Y, Ljunggren, H-G, Lohoff, M, Lombardi, G, Lopez, L, Lopez-Botet, M, Lovett-Racke, AE, Lubberts, E, Luche, H, Ludewig, B, Lugli, E, Lunemann, S, Maecker, HT, Maggi, L, Maguire, O, Mair, F, Mair, KH, Mantovani, A, Manz, RA, Marshall, AJ, Martinez-Romero, A, Martrus, G, Marventano, I, Maslinski, W, Matarese, G, Mattioli, AV, Maueroder, C, Mazzoni, A, McCluskey, J, McGrath, M, McGuire, HM, McInnes, IB, Mei, HE, Melchers, F, Melzer, S, Mielenz, D, Miller, SD, Mills, KHG, Minderman, H, Mjosberg, J, Moore, J, Moran, B, Moretta, L, Mosmann, TR, Mueller, S, Multhoff, G, Munoz, LE, Munz, C, Nakayama, T, Nasi, M, Neumann, K, Ng, LG, Niedobitek, A, Nourshargh, S, Nunez, G, O'Connor, J-E, Ochel, A, Oja, A, Ordonez, D, Orfao, A, Orlowski-Oliver, E, Ouyang, W, Oxenius, A, Palankar, R, Panse, I, Pattanapanyasat, K, Paulsen, M, Pavlinic, D, Penter, L, Peterson, P, Peth, C, Petriz, J, Piancone, F, Pickl, WF, Piconese, S, Pinti, M, Pockley, AG, Podolska, MJ, Poon, Z, Pracht, K, Prinz, I, Pucillo, CEM, Quataert, SA, Quatrini, L, Quinn, KM, Radbruch, H, Radstake, TRDJ, Rahmig, S, Rahn, H-P, Rajwa, B, Ravichandran, G, Raz, Y, Rebhahn, JA, Recktenwald, D, Reimer, D, Reis e Sousa, C, Remmerswaal, EBM, Richter, L, Rico, LG, Riddell, A, Rieger, AM, Robinson, JP, Romagnani, C, Rubartelli, A, Ruland, J, Saalmueller, A, Saeys, Y, Saito, T, Sakaguchi, S, Sala-de-Oyanguren, F, Samstag, Y, Sanderson, S, Sandrock, I, Santoni, A, Sanz, RB, Saresella, M, Sautes-Fridman, C, Sawitzki, B, Schadt, L, Scheffold, A, Scherer, HU, Schiemann, M, Schildberg, FA, Schimisky, E, Schlitzer, A, Schlosser, J, Schmid, S, Schmitt, S, Schober, K, Schraivogel, D, Schuh, W, Schueler, T, Schulte, R, Schulz, AR, Schulz, SR, Scotta, C, Scott-Algara, D, Sester, DP, Shankey, TV, Silva-Santos, B, Simon, AK, Sitnik, KM, Sozzani, S, Speiser, DE, Spidlen, J, Stahlberg, A, Stall, AM, Stanley, N, Stark, R, Stehle, C, Steinmetz, T, Stockinger, H, Takahama, Y, Takeda, K, Tan, L, Tarnok, A, Tiegs, G, Toldi, G, Tornack, J, Traggiai, E, Trebak, M, Tree, TIM, Trotter, J, Trowsdale, J, Tsoumakidou, M, Ulrich, H, Urbanczyk, S, van de Veen, W, van den Broek, M, van der Pol, E, Van Gassen, S, Van Isterdael, G, van Lier, RAW, Veldhoen, M, Vento-Asturias, S, Vieira, P, Voehringer, D, Volk, H-D, von Borstel, A, von Volkmann, K, Waisman, A, Walker, RV, Wallace, PK, Wang, SA, Wang, XM, Ward, MD, Ward-Hartstonge, KA, Warnatz, K, Warnes, G, Warth, S, Waskow, C, Watson, JV, Watzl, C, Wegener, L, Weisenburger, T, Wiedemann, A, Wienands, J, Wilharm, A, Wilkinson, RJ, Willimsky, G, Wing, JB, Winkelmann, R, Winkler, TH, Wirz, OF, Wong, A, Wurst, P, Yang, JHM, Yang, J, Yazdanbakhsh, M, Yu, L, Yue, A, Zhang, H, Zhao, Y, Ziegler, SM, Zielinski, C, Zimmermann, J, and Zychlinsky, A

Abstract

These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion.

Published
2019

135. Poster display II clinical general

Author

Gurgenyan, S., Vatinyan, S., Nikogosyan, K., Edilyan, L., Chobanyan, B., Lacourcière, Y., Marcel Dumont, M., Lefebvre, J., Poirier, L., Côté, C., Peix, A., Alonso, O., Chae, I., Chung, J., Gutierrez, C., Kropp, J., Onsel, C., Silvasi, I., Llerena, L., Padhy, A., Garcia-Barreto, D., Trapaga, A., Asen, L., Infante, O., Ponce, F., Cabrera, L., Valiente, J., Tornes, F., Guerrero, I., Zayas, R., ones, M., Castro, J., Fayad, Y., Carrillo, R., Paz, A., Mehlsen, J., Hædersdal, C., Daou, D., Benada, A., Lebtahi, R., Idy-Peretti, I., Guludec, D., Coaguila, C., Vilain, D., Leenhardt, A., Heinicke, N., Benesch, B., Kaiser, T., Seegmüller, M., Schönberger, J., Eilles, C., Riegger, G., Holmer, S., Luchner, A., Kouris, N., Kontogianni, D., Goranitou, G., Sifaki, M., Kalkandi, E., Grassos, H., Papoulia, E., Babalis, D., Moralidis, E., Spyridonidis, T., Arsos, G., Karakatsanis, K., Karatzas, N., Parameswaran, R., Sundaram, P., Padma, S., Haridas, K., Zachariah, M., Kumar, S., Feola, M., Leonardi, G., Peano, S., Bianchi, A., Dutto, P., Guala, E., Biggi, A., Uslenghi, E., Filardi, P., Pace, L., Dellegrottaglie, S., Corrado, L., Cafiero, M., Camerino, R., Maglione, A., Polimeno, M., Zarrilli, A., Chiariello, M., Giorgetti, A., Gimelli, A., Marini, C., Schluter, M., Kusch, A., D'Aragona, I., Marzullo, P., Stanislao, M., Zanco, P., Inglese, E., Bertelli, P., Valle, G., Tassone, F., Pepino, R., Francini, A., Garrone, O., Occelli, M., Merlano, M., Florimonte, L., Pagani, L., Piatti, L., Butti, I., Maffioli, L., Casorelli, E., Dottore, F., Gentili, G., Agostini, M., Pieri, P., Milan, E., Giubbini, R., Mazzanti, M., Serenelli, M., Perna, G., Ferro, A., Duilio, C., Santomauro, M., Salvatore, M., Cuocolo, A., Bertagna, F., Bosio, G., Terzi, A., Paghera, B., Kaneta, T., Otani, H., Hakamatsuka, T., Fukuda, H., Nakazato, R., Moroi, M., Kunimasa, T., Furuhashi, T., Sugi, K., Yasuhi, W., Akihiro, S., Yukawa, A., Ryu, K., Kimio, T., Yasuhiko, T., Nariaki, E., Yasunori, W., Akashi, Y., Musha, H., Kida, K., Itoh, K., Inoue, K., Kawasaki, K., Hashimoto, N., Nakazawa, K., Miyake, F., Fukuzawa, S., Ozawa, S., Inagaki, M., Sugioka, J., Okino, S., Matsuo, S., Matsumoto, T., Nakae, I., Masuda, D., Horie, M., Mori, Y., Takahashi, K., Masai, M., Kawasaki, D., Kanemori, T., Okuda, S., Tanabe, K., Ohyanagi, M., OKuda, S., Toyama, T., Hoshizaki, H., Seki, R., Isobe, N., Kawaguchi, R., Oshima, S., Taniguchi, K., Nakagawa, K., Sekine, T., Yamazaki, M., Komuro, I., Kim, K., Teramoto, N., Jino, H., Ohta, Y., Watabe, H., Hayashi, T., Iida, H., Nishimura, T., Nagae, A., Morishima, K., Shigeyama, T., Shimoyama, K., Yoshino, H., Kawai, Y., Jeong, S., Lee, J., Seo, J., Bae, J., Ahn, B., Chae, S., Lee, K., Cho, I., Chun, K., Won, K., Lee, H., Hong, G., Park, J., Shin, D., Kim, Y., Shim, B., Pavlovic, J., Peovska, I., Vavlukis, M., Gorceva, D., Majstorov, V., Alexanderson, E., Meave, A., Ricalde, A., Teresinska, A., Sliwinski, M., Konieczna, S., Szymanska, M., Hendzel, P., Juraszynski, Z., Debski, A., Szumilak, B., Kostkiewicz, M., Wilkolek, P., Pasowicz, M., Klimeczek, P., Pieniazek, P., Przewlocki, T., Pieculewicz, M., Tracz, W., Szot, W., Trebacz, J., Zmudka, K., Podolec, P., Dziuk, M., Kazmierczak, A., Kot, E., Pietrzykowski, J., Cholewa, M., Coutinho, M., Correia, M., Cantinho, G., Conceição, I., Bernardes, A., Silva, A., Gaspar, F., Cunha, J., Lourenço, C., Roque, C., Ferrer-Antunes, A., Ferreira, M., Providência, L., Lima, J., Abreu, A., Castillejos, L., Henriksson, I., Oliveira, L., Rosário, L., Geão, A., Pereira, E., Colarinha, P., Romero-Farina, G., Candell-Riera, J., Aguadé-Bruix, S., Leon, G., Caresia, A., Mila-Lopez, M., Garcia-Alonso, C., Pifarre-Montaner, P., Negre-Buso, M., Castell-Conesa, J., Mestre-Fusco, A., Porta-Biosca, F., Muxi, A., Paredes, P., Ortin, J., Duch, J., Diaz-Infante, E., Fuertes, S., Orus, J., Mont, L., Pons, F., Pollack, C., Hellermann, J., Namdar, M., Siegrist, P., Koepfli, P., Bartenstein, N., Schurr, U., Jenni, R., Kaufmann, P., Hassad, R., Hamami, H., Sellem, A., Brahim, H., Caglar, M., Mahmoudian, B., Aytemir, K., Kahraman, S., Arýcý, M., Kabakcý, G., Karabulut, E., Akincioglu, C., Berman, D., Nishina, H., Hayes, S., Kavanagh, P., Friedman, J., Slomka, P., Germano, G., Entok, E., Cavusoglu, Y., Vardareli, E., Timuralp, B., Cheetham, A., Naylor, V., Ghiotto, F., McGhie, J., Al-Housni, M., Kelion, A., Hutchings, F., Hinton-Taylor, S., Birkbeck, P., Thatikonda, S., Feldkamp, M., Rosamond, T., Raza, M., Panjrath, G., Haider, A., Jain, D., Yang, A., Schumacher, R., Reynolds, J., Clark, E., Speiser, D., Schindel, M., Hackney, T., Vacek, J., Jindal, V., Dim, U., Hamburg, L., Mouradian, V., Nichols, K., Akinboboye, O., Snyder, K., Polepalle, D., DePuey, G., Khattak, H., Friedman, M., Thompson, L., Thompson, R., McGhie, A., Moser, K., O'Keefe, J., Fritsch, N., Bateman, T., Mut, F., Vidal, I., Rener, A., Nuñez, M., Alvarez, B., and Beretta, M.

Published
2018

139. Der relative Körperfettgehalt ist bei Patienten mit Leberzirrhose mit dem Auftreten von Tod und Komplikationen zur Lebertransplantation assoziiert

Author

Engelmann, C, additional, Schob, S, additional, Nonnenmacher, I, additional, Werlich, L, additional, Macnaughtan, J, additional, Aehling, N, additional, Herber, A, additional, Surov, A, additional, Kaiser, T, additional, Jalan, R, additional, Seehofer, D, additional, Moche, M, additional, and Berg, T, additional

Published
2019
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142. Measurement of Temperature Fluctuations and Microscopic Growth Rates in a Silicon Floating Zone Under Microgravity

Author

Croell, Arne, Schweizer, Markus, Dold, P, Kaiser, T, Lichtensteiger, M, and Benz, K. W

Subjects
Materials Processing
Abstract

USA Several microgravity experiments on sounding rockets and the Space Shuttle have shown that time-dependent thermocapillary (Marangoni) convection is the major cause for the formation of dopant striations in floating-zone grown semiconductor crystals, at least in small-scale systems not employing RF heating. To quantify this correlation, a silicon floating-zone experiment was performed during the TEXUS36 flight (February 7, 1998) in the monoellipsoid mirror furnace TEM02-ELLI. During the experiment, temperature fluctuations in the silicon melt zone and the microscopic growth rate were simultaneously measured. Temperature fluctuations of 0.5 C - 0.7 C with main frequencies between 0.1 Hz and 0.3 Hz were detectable. The microscopic growth rate fluctuated considerably around the average growth rate of 1 mm/min: rates from 4 mm/min to negative values (backmelting) were observed. Dopant striations are clearly visible in the Sb-doped crystal. They were characterized by Spreading Resistance measurements and Differential Interference Contrast microscopy. The frequencies associated with the dopant inhomogeneities correspond quite well with those of the temperature fluctuations and microscopic growth rates. 3D numerical simulations were performed to predict the optimum position of the temperature sensor, to evaluate characteristic temperature amplitudes and frequencies, and to give insight into the instability mechanisms of Marangoni convection in this configuration. The simulations were in good agreement with the experimental values, showing temperature fluctuations with frequencies ? 0.25 Hz and amplitudes up to 1.8 C at a position equivalent to that of the sensor tip in the experiment.

Published
1999

144. Molecular quantification and differentiation of Candida species in biological specimens of patients with liver cirrhosis

Author

Krohn, S., Zeller, K., Böhm, S., Chatzinotas, Antonis, Harms, Hauke, Hartmann, I., Heidtmann, Anett, Herber, A., Kaiser, T., Treuheit, M., Hoffmeister, A., Berg, T., Engelmann, C., Krohn, S., Zeller, K., Böhm, S., Chatzinotas, Antonis, Harms, Hauke, Hartmann, I., Heidtmann, Anett, Herber, A., Kaiser, T., Treuheit, M., Hoffmeister, A., Berg, T., and Engelmann, C.

Abstract

Patients with liver cirrhosis are susceptible to fungal infections. Due to low sensitivity of culture-based methods, we applied a real-time PCR assay targeting the 18S rRNA gene in combination with direct sequencing and terminal-restriction fragment length polymorphism (T-RFLP) in order to establish a novel tool to detect fungal DNA and to quantify and differentiate Candida DNA, also in polyfungal specimens. In total, 281 samples (blood n = 135, ascites n = 92, duodenal fluid n = 54) from 135 patients with liver cirrhosis and 52 samples (blood n = 26, duodenal fluid n = 26) from 26 control patients were collected prospectively. Candida DNA was quantified in all samples. Standard microbiological culture was performed for comparison. Blood and ascites samples, irrespective of the patient cohort, showed a method-independent low fungal detection rate of approximately 1%, and the Candida DNA content level did not exceed 3.0x101 copies ml-1 in any sample. In contrast, in duodenal fluid of patients with liver cirrhosis high fungal detection rates were discovered by using both PCR- and culture-based techniques (81.5% vs. 66.7%; p = 0.123) and the median level of Candida DNA was 3.8x105 copies ml-1 (2.3x102-6.3x109). In cirrhosis and controls, fungal positive culture results were confirmed by PCR in 96% and an additional amount of 44% of culture negative duodenal samples were PCR positive. Using T-RFLP analysis in duodenal samples, overall 85% of results from microbial culture were confirmed and in 75% of culture-negative but PCR-positive samples additional Candida species could be identified. In conclusion, PCR-based methods and subsequent differentiation of Candida DNA might offer a quick approach to identifying Candida species without prior cultivation.

Published
2018

146. Dual-SNOM investigations of multimode interference in plasmonic strip waveguides

Author

Klein, A.E., Janunts, N., Schmidt, S., Bin Hasan, S., Etrich, C., Fasold, S., Kaiser, T., Rockstuhl, C., Pertsch, T., and Publica

Abstract

The ability of squeezing and guiding light in nanoscale plasmonic waveguides makes them especially interesting for photonic circuits. In spite of reported realizations of plasmonic waveguides, experimental studies on the content of plasmonic modes and mode-selective excitation methods are rare. We apply here a Dual-SNOM technique, incorporating two aperture scanning near-field optical microscopes, for simultaneous near-field excitation and detection of plasmonic modes in gold strip waveguides. Depending on the waveguide width, either a single waveguide mode or a beating pattern of several modes is observed. The relative excitation strengths of the individual modes in multi-mode waveguides are shown to be controllable by the lateral position of the excitation tip. The excitation coefficients are described by an analytical model and the results are fully corroborated by analytical calculations and full-wave numerical simulations. The Dual-SNOM technique provides a "non-invasive" method of local excitation and detection of photonic modes thus making it a valuable tool for in situ characterization of complex photonic micro-and nanostructures.

Published
2017

147. A new machine-learning-based prediction of survival in patients with end-stage liver disease

Author

Gibb Sebastian, Berg Thomas, Herber Adam, Isermann Berend, and Kaiser Thorsten

Subjects
end-stage liver disease, il-6, machine-learning, meld, risk stratification, survival estimation, Medical technology, R855-855.5
Abstract

The shortage of grafts for liver transplantation requires risk stratification and adequate allocation rules. This study aims to improve the model of end-stage liver disease (MELD) score for 90-day mortality prediction with the help of different machine-learning algorithms.

Published
2023
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148. A Predictive Model of Fragmentation using Adaptive Mesh Refinement and a Hierarchical Material Model

Author

Koniges, A, primary, Masters, N, additional, Fisher, A, additional, Anderson, R, additional, Eder, D, additional, Benson, D, additional, Kaiser, T, additional, Gunney, B, additional, Wang, P, additional, Maddox, B, additional, Hansen, J, additional, Kalantar, D, additional, Dixit, P, additional, Jarmakani, H, additional, and Meyers, M, additional

Published
2009
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150. Multicentre reference values for cardiac magnetic resonance imaging derived ventricular size and function for children aged 0–18 years.

Author

Ven, J P G van der, Sadighy, Z, Buechel, E R Valsangiacomo, Sarikouch, S, Robbers-Visser, D, Kellenberger, C J, Kaiser, T, Beerbaum, P, Boersma, E, and Helbing, W A

Subjects
CARDIOVASCULAR disease diagnosis, HEART ventricles, MAGNETIC resonance imaging, REFERENCE values, REGRESSION analysis, BODY mass index, DESCRIPTIVE statistics, MANN Whitney U Test, CHILDREN
Abstract

Aims Cardiovascular magnetic resonance (CMR) imaging is an important tool in the assessment of paediatric cardiac disease. Reported reference values of ventricular volumes and masses in the paediatric population are based on small cohorts and several methodologic differences between studies exist. We sought to create steady-state free precession (SSFP) CMR reference values for biventricular volumes and mass by combining data of previously published studies and re-analysing these data in a standardized manner. Methods and results A total of 141 healthy children (68 boys) from three European centres underwent cine-SSFP CMR imaging. Cardiac structures were manually contoured for end-diastolic and end-systolic phases in the short-axis orientation according to current standardized CMR post-processing guidelines. Volumes and masses were derived from these contours. Age-related reference curves were constructed using the lambda mu sigma method. Median age was 12.7 years (range 0.6–18.5). We report biventricular volumes and masses, unindexed and indexed for body surface area, stratified by age groups. In general, boys had approximately 15% higher biventricular volumes and masses compared with girls. Only in children aged <6 years old no gender differences could be observed. Left ventricle ejection fraction was slightly higher in boys in this study population (median 67% vs. 65%, P = 0.016). Age-related reference curves showed non-linear relations between age and cardiac parameters. Conclusion We report volumetric SSFP CMR imaging reference values for children aged 0–18 years old in a relatively large multi-centre cohort. These references can be used in the follow-up of paediatric cardiac disease and for research purposes. [ABSTRACT FROM AUTHOR]

Published
2020
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