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Background: With rapid socioeconomic development and transition, associations between socioeconomic status (SES) and hypertension remained uncertain in China. We aimed to examine the health effects of SES on hypertension incidence and explore the sex differences among Chinese adults. Methods: We included 53 891 participants without hypertension from the China-PAR (Prediction for Atherosclerotic Cardiovascular Disease Risk in China) project. SES was evaluated by education level, occupation prestige, and household monthly per capita income, and categorized into low, medium, and high groups. Hazard ratios and their 95% CIs were calculated using Cox proportional hazards regression models. Results: Compared with high SES, participants with medium SES (hazard ratio, 1.142 [95% CI, 1.068–1.220]) or low SES (hazard ratio, 1.166 [95% CI, 1.096–1.241]) had increased risks of incident hypertension in multivariate analyses. Interactions between SES and sex on hypertension were observed, with more pronounced adverse effects of lower SES among women. The corresponding hazard ratios (95% CIs) for low SES group were 1.270 (1.155–1.397) for women and 1.086 (0.999–1.181) for men. Effects of occupation prestige on hypertension were the strongest among SES factors. Conclusions: Our study provided the compelling evidence from China that lower SES was associated with incident hypertension and women were more susceptible. These findings will have substantial implications on future hypertension prevention and management, especially among women. Sex-specific approaches are warranted to reduce socioeconomic disparities.

A steric hindrance strategy was used to prepare intramolecular hydrogen bond-controlled thermosensitive fluorescent carbon dots (CDs) via the solvothermal treatment of o-phenylenediamine respectively with three dihydroxybenzene isomers. The CDs obtained from different isomers have very similar morphology, surfaces, and photophysical properties but exhibited different thermal sensitivities. Meanwhile, the orange-emitting CDs (p-CDs) obtained from o-phenylenediamine and p-hydroquinone exhibited an optimal thermal sensitivity of 1.1%/°C. Comprehensive experimental characterizations and theoretical calculations revealed that even a small difference in substituent locations in the phenyl ring of the precursors can considerably affect the formation of intramolecular hydrogen bonds and that the CDs with strong intramolecular hydrogen bonds exhibited poor thermosensitivity. The p-CDs were incorporated with reference CDs (B-CDs) that exhibited heating-quenching blue emission through electrostatic self-assembly to construct a dual-emission probe (p-CDs/B-CDs), which exhibited a thermal sensitivity of 2.0%/°C. Test strips based on the p-CDs/B-CDs were prepared to measure temperature fluctuations based on sensitive and instant fluorescence color evolution. Further, this fluorescent colorimetry was successfully applied to a test strip-integrated wearable wristband to measure the body temperature. This study establishes an inherent relationship between precursors and the resulting intramolecular hydrogen bonds for precisely tuning the thermal sensitivity of CDs. It also offers a visual quantitative strategy for the early warning of abnormal body temperatures.

Lung cancer is the leading cause of cancer-related death in many countries, and an accurate histopathological diagnosis is of great importance in subsequent treatment. The aim of this study was to establish the random forest (RF) model based on radiomic features to automatically classify and predict lung adenocarcinoma (ADC), lung squamous cell carcinoma (SCC), and small cell lung cancer (SCLC) on unenhanced computed tomography (CT) images. Eight hundred and fifty-two patients (mean age: 61.4, range: 29–87, male/female: 536/316) with preoperative unenhanced CT and postoperative histopathologically confirmed primary lung cancers, including 525 patients with ADC, 161 patients with SCC, and 166 patients with SCLC, were included in this retrospective study. Radiomic features were extracted, selected, and then used to establish the RF classification model to analyse and classify primary lung cancers into three subtypes, including ADC, SCC, and SCLC according to histopathological results. The training (446 ADC, 137 SCC, and 141 SCLC) and testing cohorts (79 ADC, 24 SCC, and 25 SCLC) accounted for 85% and 15% of the whole datasets, respectively. The prediction performance of the RF classification model was evaluated by F1 scores and the receiver operating characteristic (ROC) curve. On the testing cohort, the areas under the ROC curve (AUC) of the RF model in classifying ADC, SCC, and SCLC were 0.74, 0.77, and 0.88, respectively. The F1 scores achieved 0.80, 0.40, and 0.73 in ADC, SCC, and SCLC, respectively, and the weighted average F1 score was 0.71. In addition, for the RF classification model, the precisions were 0.72, 0.64, and 0.70; the recalls were 0.86, 0.29, and 0.76; and the specificities were 0.55, 0.96, and 0.92 in ADC, SCC, and SCLC. The primary lung cancers were feasibly and effectively classified into ADC, SCC, and SCLC based on the combination of RF classification model and radiomic features, which has the potential for noninvasive predicting histological subtypes of primary lung cancers.

A novel Pd/SnO2 nanocomposite with abundant Pd(100)/SnO2 interfaces shows a record-high mass activity of 14.55 A mgPd−1 towards electrochemical formic acid oxidation.

The novel S vacancy-rich In2S3@Cu2S nanorod heterostructure arrays were in situ grown on copper foam, constructing an efficient electrocatalyst for pH-universal HER.

A topological Archimedean polyhedron of CoFe PBA was synthesized via a Sn-induced crystal growth regulation strategy, which could serve as a highly-efficient HER electrocatalyst.

Deep blue thermally activated delayed fluorescence of carbon dots with lifetime up to 2.02 s, which the longest, has been achieved.

The increase of per capita disposable income makes personal financial management urgent, and Internet financial products show great development potential. Based on the perspective of consumers, this paper selects Bengbu City to conduct a field survey to empirically study the influencing factors of consumers' willingness to adopt Internet financial products in Bengbu City. Basic statistical analysis, factor analysis and other methods are used for data analysis, and corresponding conclusions and suggestions are drawn.

ObjectiveTo examine whether adherence to ideal cardiovascular health (CVH) can mitigate the genetic risk of coronary artery disease (CAD) in non-European populations.MethodsFine and Grey’s models were used to calculate HRs and their corresponding 95% CIs, as well as the lifetime risk of CVH metrics across Polygenic Risk Score (PRS) categories.ResultsWe included 39 755 individuals aged 30–75 years in Chinese prospective cohorts. 1275 CAD cases were recorded over a mean follow-up of 12.9 years. Compared with unfavourable CVH profile (zero to three ideal CVH metrics), favourable CVH profile (six to seven ideal CVH metrics) demonstrated similar relative effects across PRS categories, with the HRs of 0.40 (95% CI 0.24 to 0.67), 0.41 (95% CI 0.32 to 0.52) and 0.36 (95% CI 0.26 to 0.52) in low (bottom quintile of PRS), intermediate (two to four quintiles of PRS) and high (top quintile of PRS) PRS categories, respectively. For the absolute risk reduction (ARR), individuals with high PRS achieved the greatest benefit from favourable CVH, mitigating the risk to the average level of population (from 21.1% to 8.7%), and the gradient was strengthened in individuals at the top 5% of PRS. Moreover, compared with individuals at low PRS, those at high PRS obtained longer CAD-free years (2.6 vs 1.1) from favourable CVH at the index age of 35 years.ConclusionFavourable CVH profile reduced the CAD relative risk by similar magnitude across PRS categories, while the ARR from favourable CVH was most pronounced in high PRS category. Attaining favourable CVH should be encouraged for all individuals, especially in individuals with high genetic susceptibility.

With the continuous deepening of China's reform and opening up, the level of foreign direct investment has been constantly improving, which has played an important role in promoting the rapid development of China's economy. In today's world economic development, China's foreign direct investment is growing in both quantity and quantity. The development of foreign economy is the objective requirement of the trend of economic globalization and the inevitable trend of China's economic development. After the reform and opening up, many Chinese companies have gone global. However, Chinese companies face various obstacles in foreign investment and difficulties in overseas investment. This paper expounds the current situation of China's foreign investment, analyzes the problems existing in China's foreign investment, finds out the obstacles to China's foreign investment, and takes corresponding countermeasures.