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571 results on '"Ina, K."'

103. World J Clin Oncol: Lentinan prolonged survival in patients with gastric cancer receiving S-1-based chemotherapy

Author

Ina, K., Furuta, R., and Kataoka, T.

Subjects
Stomach cancer -- Drug therapy -- Research, Chemotherapy -- Health aspects, Cancer -- Chemotherapy, Health
Abstract

AIM: To examine whether administration of lentinan, purified [beta]-1, 3-glucan, can prolong survival in advanced gastric cancer patients receiving S-1-based chemotherapy. METHODS: Since 2004, 78 patients with metastatic or recurrent [...]

Published
2011

119. Entwicklungszusammenarbeit in Indien : Trainingsprogramm für Fach- und Führungskräfte

Author

Ina K Saure, Annika Tillmans, Alexander Thomas, Ina K Saure, Annika Tillmans, and Alexander Thomas

Abstract

Das Trainingsprogramm wendet sich an ausreisende Fach- und Führungskräfte der deutschen Entwicklungszusammenarbeit, an interkulturelle Trainer/innen und an interessierte Personen, die sich bezogen auf Indien mit interkulturellen Aspekten der Zusammenarbeit auseinandersetzen wollen. Es eignet sich zum Selbststudium und auch zum Einsatz in interaktiven Trainings. Die kulturelle Bedingtheit der eigenen Wert- und Orientierungssysteme wird anhand realer Fallbeispiele verdeutlicht und zielt darauf ab, Denk- und Verhaltensweisen der indischen Partner besser zu verstehen, um für beide Seiten befriedigende und nachhaltige Lösungen zu finden.'Insgesamt stellt das vorliegende Buch einen wertvollen und nützlichen Beitrag dar, um in einer zunehmend globalisierten Welt Verständnis für kulturelle Vielfalt zu fördern und die Entwicklung zu mehr sozialer Gerechtigkeit zu unterstützen.'aus dem Vorwort von Gerhard Seidel Die Autoren Ina Kristin Saure, Diplom-Psychologin mit der Zusatzqualifikation Verhaltens- und Kommunkationstrainer, studierte an der Humboldt Universität zu Berlin und ist als interkulturelle Trainerin bei der Trainingsfabrik in Berlin tätig. Annika Tillmans, Diplom-Psychologin mit der Zusatzqualifikation Verhaltens- und Kommunikationstrainerin, studierte an der Humboldt Universität zu Berlin und ist als freie interkulturelle Trainerin in Berlin tätig. Dr. phil. Alexander Thomas ist Professor für Sozialpsychologie und Organisationspsychologie an der Universität Regensburg.

Published
2006

125. Targeting Determinants of Dosage Compensation in Drosophila

Author

Rosemarie Lamm, Vladimir I Shelest, Gregor D. Gilfillan, Ina K. Dahlsveen, and Peter B. Becker

Subjects
Male, Cancer Research, X Chromosome, lcsh:QH426-470, Amino Acid Motifs, Molecular Sequence Data, Biology, Genetics/Epigenetics, Chromosomes, Sex Factors, Dosage Compensation, Genetic, Genetics, Animals, Binding site, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, X chromosome, Binding Sites, Dosage compensation, Polytene chromosome, Base Sequence, fungi, Computational Biology, Genetics/Chromosome Biology, Dosage compensation complex, Chromatin, lcsh:Genetics, Drosophila melanogaster, Genes, DCC, Drosophila, Female, Genetics/Gene Expression, Sequence motif, Chromatin immunoprecipitation, Research Article
Abstract

The dosage compensation complex (DCC) in Drosophila melanogaster is responsible for up-regulating transcription from the single male X chromosome to equal the transcription from the two X chromosomes in females. Visualization of the DCC, a large ribonucleoprotein complex, on male larval polytene chromosomes reveals that the complex binds selectively to many interbands on the X chromosome. The targeting of the DCC is thought to be in part determined by DNA sequences that are enriched on the X. So far, lack of knowledge about DCC binding sites has prevented the identification of sequence determinants. Only three binding sites have been identified to date, but analysis of their DNA sequence did not allow the prediction of further binding sites. We have used chromatin immunoprecipitation to identify a number of new DCC binding fragments and characterized them in vivo by visualizing DCC binding to autosomal insertions of these fragments, and we have demonstrated that they possess a wide range of potential to recruit the DCC. By varying the in vivo concentration of the DCC, we provide evidence that this range of recruitment potential is due to differences in affinity of the complex to these sites. We were also able to establish that DCC binding to ectopic high-affinity sites can allow nearby low-affinity sites to recruit the complex. Using the sequences of the newly identified and previously characterized binding fragments, we have uncovered a number of short sequence motifs, which in combination may contribute to DCC recruitment. Our findings suggest that the DCC is recruited to the X via a number of binding sites of decreasing affinities, and that the presence of high- and moderate-affinity sites on the X may ensure that lower-affinity sites are occupied in a context-dependent manner. Our bioinformatics analysis suggests that DCC binding sites may be composed of variable combinations of degenerate motifs., Synopsis In fruit flies, just like in humans, the two sexes are distinguished by different sex chromosomes. Females have two X chromosomes and hence a double dose of all X-linked genes when compared to males, which only have a single X chromosome. This different gene dosage needs to be compensated for by adjusting transcription levels such that male and female cells synthesize equal amounts of gene products. In Drosophila melanogaster, dosage compensation occurs by doubling the transcription of many genes on the single male X. This chromosome-wide control is achieved by a male-specific dosage compensation complex (DCC), which contains enzymes, structural proteins, and non-coding RNA. How is the DCC able to distinguish the X chromosome from the autosomes for selective interaction? In the following article, the authors identify and characterize several novel DNA sequences on the X chromosome that can recruit the DCC. Their results suggest that the X chromosome contains a large number of binding sites for the DCC, which are made up of combinations of degenerate sequence elements. These elements constitute binding sites with varying affinities for the complex. Collectively, their abundance on the X chromosome restricts the action of DCC to the X chromosomal territory.

Published
2006

126. 525P - A Phase III Study of Eagle Comparing Two Doses of Bevacizumab Combined with Folfiri in the Second-Line Setting After First-Line Treatment with Bevacizumab Plus Oxaliplatin-Based Therapy : Kras Subgroup Findings

Author

Munemoto, Y., Iwamoto, S., Takahashi, T., Tamagawa, H., Nakamura, M., Kato, T., Hata, T., Denda, T., Morita, Y., Inukai, M., Kunieda, K., Nagata, N., Kurachi, K., Ina, K., Oshiro, M., Shimoyama, T., Baba, H., Oba, K., Sakamoto, J., and Mishima, H.

Published
2014
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135. Reducing Errors through a Web-Based Self-Management Support System.

Author

EKSTEDT, Mirjam, BØRØSUND, Elin, SVENNINGSEN, Ina K., and RULAND, Cornelia M.

Abstract

Web-based self-management support systems SMSS, can successfully assist a wide range of patients with information and self-management support. O or as a stand-alone service, are e-messages. This study describes how one component of a multi component SMSS, an e-message service, in which patients with breast cancer could direct questions to nurses, physicians or social workers at the hospital where they were being treated, had an influence on safety and continuity of care. Ninety-one dialogues consisting of 284 messages were analysed. The communications between patients and the healthcare team revealed that the e-messages service served as a means for quality assurance of information, for double-checking and for coordination of care. We give examples of how an e-mail service may improve patients’ knowledge in a process of taking control over their own care – increasingly important in a time of growing complexity and specialization in healthcare. It remains to be tested whether an e-message service can improve continuity of care and prevent or mitigate medical mishaps. [ABSTRACT FROM AUTHOR]

Published
2014
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147. SONGLINES AND TOUCHSTONES.

Author

Montgomery-Andersen, Ruth and Borup, Ina K.

Subjects
*MATERNAL health services, *FAMILIES, *CULTURE, *GREENLANDERS, *FOCUS groups, *INFANTS, PERINATAL care
Abstract

This paper aims to focus on how family and community in Greenland perceive support- giving during the perinatal period. It explores Greenlanders use of storytelling as a health-promoting tool in the perinatal period. It is research set in Greenland, but analysed in a larger context. Using an ethnographic approach to subject matter, the paper is based on a series of qualitative interviews and focus groups conducted between 2003 and 2011 with mothers and fathers. Ethnographic content analysis, interviews and dialogues with Culture Bearers were used to analyse and set the stories into a cultural perspective. The child was described as the centre of the family and the family as the bedrock of life. The mothers, fathers and Culture Bearers presented three main concepts in their stories: 1) my family @@@ a safe harbour, 2) the child as the centre of the family, and 3) the equal sharing of burden and joy. [ABSTRACT FROM AUTHOR]

Published
2013
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150. The Use of Plants to Improve Indoor Air Quality in Small Office Space.

Author

Aini Jasmin, G., Noorizan, M., Suhardi, M., Murad, A. G., and Ina, K.

Subjects
INDOOR air quality, HOUSE plants, OFFICE buildings, VOLATILE organic compounds, SICK building syndrome, POISONS, GAS detectors
Abstract

Exposure to volatile organic compounds (VOC) can cause a series of effects towards human health. VOC is also associated with Sick Building Syndrome and other building related illnesses. Common materials found in every home and place of business may cause elevated exposure to toxic chemicals. The aim of this study was to examine the best indoor plants that could be used to improve indoor air quality in a small office space. In this study, the concentration of VOC inside a room was monitored before and after the test, using Aeroquol Model S500 VOC Gas Detector and by using oil-based paint painted on a panel measuring 0.05 x 0.05 m in order to create a minimum of 3ppm of VOC Three types of tropical indoor plants were used in this study; Nephrolepis exaltata, Rhapis excelsa and Dracaena fragrans. Data were monitored for eight hours at 10 minutes interval. The results showed no significant differences between the number of pots and the type of plants used in reducing VOC content in the real room environment. This was probably due to several factors, such as the interference of outside air and the condition of the experimental room. This experiment suggests that further experiments should be carried out in a controlled environment to improve our knowledge of how indoor plants can improve indoor air quality, and thus improve human health and well-being. [ABSTRACT FROM AUTHOR]

Published
2012

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