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101. Ultra-Weitwinkel Retina-Imaging

Author

Schmitz-Valckenberg, Steffen, Steinberg, J.S., Graham, V., Fleckenstein, M., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Ziel der Studie war die Evaluation eines neuen „non-contact“ optischen Systems zum Ultra-Weitwinkel Retina-Imaging mittels konfokaler Scanning Laser Ophthalmoskopie (cSLO). Methoden: Retinale Bildgebung mittels verschiedener cSLO-Modalitäten, einschließlich Nah-infrarot[for full text, please go to the a.m. URL], 176. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2014
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102. Multi-country real-life experience of anti-vascular endothelial growth factor therapy for wet age-related macular degeneration

Author

Holz, F.G., Tadayoni, R., Beatty, S., Berger, A., Cereda, M.G., Cortez, R., Hoyng, C.B., Hykin, P., Staurenghi, G., Heldner, S., Bogumil, T., Heah, T., Sivaprasad, S., Holz, F.G., Tadayoni, R., Beatty, S., Berger, A., Cereda, M.G., Cortez, R., Hoyng, C.B., Hykin, P., Staurenghi, G., Heldner, S., Bogumil, T., Heah, T., and Sivaprasad, S.

Abstract

Contains fulltext : 153434.pdf (Publisher’s version ) (Open Access), BACKGROUND/AIMS: Real-life anti-vascular endothelial growth factor (VEGF) therapy use in patients with wet age-related macular degeneration (wAMD) was assessed in a retrospective, observational study in Canada, France, Germany, Ireland, Italy, the Netherlands, UK and Venezuela. METHODS: Medical records of patients with wAMD, who started ranibizumab treatment between 1 January 2009 and 31 August 2009, were evaluated. Data were collected until the end of treatment and/or monitoring or until 31 August 2011. RESULTS: 2227 patients who received >/=1 anti-VEGF injection with a baseline visual acuity assessment and >/=1 postbaseline visual acuity assessment for the treated eye were evaluated. Visual acuity improved until about day 120; thereafter, visual acuity gains were not maintained. Mean change in visual acuity score from baseline to years 1 and 2 was +2.4 and +0.6 letters, respectively. Patients received a mean of 5.0 and 2.2 injections in the first and second year, respectively. There were substantial differences in visual outcomes and injection frequency between countries. More frequent visits and injections were associated with greater improvements in visual acuity. CONCLUSIONS: In clinical practice, fewer injections are administered than in clinical trials. Anti-VEGF treatment resulted in an initial improvement in visual acuity; however, this was not maintained over time. TRIAL REGISTRATION NUMBER: NCT01447043.

Published
2015

103. Vergleich von MultiColor konfokaler Scanning Laser Ophthalmoskopie und Farb-Funduskamera-Photographie

Author

Schmitz-Valckenberg, Steffen, Göbel, A.P., Steinberg, J.S., Fleckenstein, M., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Ziel der Untersuchung ist der Vergleich zwischen konventioneller Farb-Funduskamera-Photographie und MultiColor konfokaler Scanning Laser Ophthalmoskopie (cSLO) im klinischen Einsatz. Methoden: Retinale Bildgebung wurde zusätzlich zu einer augenärztlichen Fundus-Untersuchung[for full text, please go to the a.m. URL], 175. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2013

104. Mikroperimetrie bei makulären Teleangiektasien Typ 2: longitudinale Ergebnisse

Author

Charbel Issa, Peter, Heeren, T., Baumüller, S., Clemons, T., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Phänotypische Untersuchungen bei Patienten mit makulären Teleangiektasien Typ 2 zeigten charakteristische parazentrale Skotome bei häufig noch guter zentraler Sehschärfe. Diese Skotome können mittels funduskorrelierter Mikroperimetrie exakt abgegrenzt werden. In [for full text, please go to the a.m. URL], 175. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2013

105. Activation of the NALP3 inflammasome induced by lipofuscin phototoxicity and lysosomale membrane permeabilisation in the RPE

Author

Krohne, Tim U., Brandstetter, C., Kopitz, J., Latz, E., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Sowohl phototoxische Effekte des Lipofuszins, als auch lokale Entzündungsprozesse im Sub-RPE-Raum werden mit der progressiven Dysfunktion und Degeneration des retinalen Pigmentepithels (RPE) im Rahmen der altersabhängigen Makuladegeneration (AMD) in Verbindung gebracht. Um einen[for full text, please go to the a.m. URL], 25. Jahrestagung der Retinologischen Gesellschaft

Published
2012

106. Imaging of focally increased pigment in early and Intermediate AMD - analysis of longitudinal alterations

Author

Göbel, Arno P., Grundei, S., Holz, F.G., and Schmitz-Valckenberg, S.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Fokale Hyperpigmentierungen stellen einen Hochrisikofaktor für die Progression der altersabhängigen Makuladegeneration (AMD) dar. Ziel dieser prospektiven Studie war die Erfassung longitudinaler Veränderungen bei früher und intermediärer AMD mittels multimodaler[for full text, please go to the a.m. URL], 25. Jahrestagung der Retinologischen Gesellschaft

Published
2012

107. Überleben subretinal implantierter humaner fetaler und adulter retinaler Pigmentepitheleinzelschichten auf Zellträgern in Kaninchen

Author

Stanzel, Boris V., Blenkinsop, T.A., Liu, Z.P., Somboonthanakij, S., Wongsawad, W., Brinken, R., Eter, N., Stern, J.H., Temple, S., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Ein Grosstiermodell für kosteneffiziente Tissue-engineering Studien zum Ersatz von retinalem Pigmentepithel (RPE) an gesundem Gewebe wurde mit Chinchilla Bastard Kaninchen entwickelt. Methoden: Fetale und adulte humane RPE Kulturen wurden für mindestens 6 Wochen auf biostabilen[for full text, please go to the a.m. URL], 25. Jahrestagung der Retinologischen Gesellschaft

Published
2012

108. A subgroup of age-related macular degeneration is associated with mono-allelic sequence variants in the ABCA4 gene

Author

Fleckenstein, Monika, Fritsche, L.G., Fiebig, B.S., Schmitz-Valckenberg, S., Bindewald-Wittich, A., Keilhauer, C.N., Renner, A.B., Mackensen, F., Moessner, A., Pauleikhoff, D., Adrion, C., Mansmann, U., Scholl, H.P., Holz, F.G., and Weber, B.H.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die altersabhängige Makuladegeneration (AMD) ist eine heterogene Erkrankung mit hoher Prävalenz und komplexer Ätiologie, die genetische und umweltbedingte Faktoren miteinschließt. Mittels Fundus Autofluoreszenz (FAF) Bildgebung kann die AMD in spezifische Phänotypen[for full text, please go to the a.m. URL], 25. Jahrestagung der Retinologischen Gesellschaft

Published
2012

109. Epidemiology of AMD

Author

Ho, L., Van Leeuwen, R., de Jong, P.T.V.M., Vingerling, J.R., Klaver, C.C., Holz, F.G., Pauleikhoff, D., Spaide, R.F., Bird, A.C., and Nederlands Herseninstituut (NIN)

Published
2012

110. Spectral domain optical coherence tomography and fundus autofluorescence imaging of retinal pigment epithelial tears

Author

Peters, Nina, Fonseca, S., Schmitz-Valckenberg, S., Fleckenstein, M., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Risse des retinalen Pigmentepithels (RPE; Hoskin et al. 1981) können zu erheblicher Sehminderung führen und spontan oder unter anti-VEGF Therapie bei altersabhängiger Makuladegeneration (AMD) entstehen. Wir untersuchten assoziierte morphologische Veränderungen mittels[for full text, please go to the a.m. URL], 24. Jahrestagung der Retinologischen Gesellschaft

Published
2011

111. Hyperreflectivity on spectral domain optical coherence tomography in macular telangiectasia type 2

Author

Baumüller, Sönke, Issa, P. Charbel, and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Untersuchung der optischen Eigenschaften der neurosensorischen Netzhaut mit der spectral domain optischen Kohärenztomographie (SD OCT) bei Makulären Teleangiektasien Typ 2 (MacTel Typ 2). Methoden: 43 Patienten mit MacTel Typ 2 und 15 Kontrollen wurden eingeschlossen. SD[for full text, please go to the a.m. URL], 24. Jahrestagung der Retinologischen Gesellschaft

Published
2011
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112. Evaluation of a semi-automated image software for quantification and progression analysis of geographic atrophy

Author

Brinkmann, Christian Karl, Schmitz-Valckenberg, S., Göbel, A.P., Fleckenstein, M., Stratmann, N., Alten, F., Herrmann, P., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Eine neue semi-automatische Software ermöglicht die Quantifizierung und Analyse der Progression der geographischen Atrophie (GA) bei altersabhängiger Makuladegeneration (AMD) anhand von Fundusautofluoreszenzaufnahmen (FAF). Wir haben die Software und die Einarbeitung in ihre Verwendung[for full text, please go to the a.m. URL], 24. Jahrestagung der Retinologischen Gesellschaft

Published
2011

113. Untersuchung der Pigmentepithelabhebung bei AMD durch SD-OCT, Nah-Infrarot-Reflexion, Fluoreszein-Angiographie und ICG-Angiographie

Author

Clemens, C.R., Alten, F., Milojcic, C., Holz, F.G., and Eter, N.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die hochauflösende, spektral-domän optische Kohärenztomographie (SD-OCT) und die konfokale Scanning Laser Ophthalmoskopie (cSLO) erlauben eine detaillierte Beurteilung der einzelnen Netzhautschichten und ihrer Veränderungen. Ziel dieser Arbeit war der Vergleich der Merkmale[for full text, please go to the a.m. URL], 173. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2011
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114. Monitoring und Wiederbehandlungsstrategie bei der exsudativen AMD - aktueller Stand

Author

Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Bei der Optimierung der anti-VEGF-Therapie der neovakulären AMD stellt sich die Frage, wie ein bestmöglicher funktioneller Erfolg mit minimalen Risiken für den Patienten und adäquatem Ressourceneinsatz erzielt werden kann. Wenngleich die Datenlage dafür spricht, dass mit monatlichen[for full text, please go to the a.m. URL], 173. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2011

115. Progression der Geographischen Atrophie - Einfluss des Partnerauges

Author

Fleckenstein, M., Schmitz-Valckenberg, S., Adrion, C., Visvalingam, S., Göbel, A.P., Mansmann, U., Holz, F.G., and FAM-Studiengruppe

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Das Wachstum von Atrophiearealen bei der AMD zeigt eine hohe interindividuelle Variabilität. Hier soll untersucht werden, ob der Status des Partnerauges Einfluss auf die Wachstumsgeschwindigkeit besitzt. Methoden: Insgesamt wurden 300 Augen mit GA (193 Patienten), die im Rahmen [for full text, please go to the a.m. URL], 173. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2011

117. Fluorescence-labeled Bevacizumab For In-vivo Molecular Imaging Of VEGF

Author

Schmitz-Valckenberg, Steffen, Licha, K., Herrmann, P., Welker, P., Eter, N., Schirner, M., and Holz, F.G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Ziel ist die Entwicklung einer fluoreszierenden molekularen Sonde für vascular endothelial growth factor (VEGF) mittels eines humanisierten monoklonalen VEGF-Antikörpers zur in-vivo Bildgebung von freiem VEGF in der Netzhaut. Methoden: Bevacizumab wurde kovalent an einen Nah-Infrarot-Indozyanin-Farbstoff[for full text, please go to the a.m. URL], 23. Jahrestagung der Retinologischen Gesellschaft

Published
2010

118. SD-OCT unterstützt die histologische Evaluation von potentiellen Bruch'sche Membran Prothesen

Author

Stanzel, Boris V., Liu, Z.P., Clemens, C.R., Brinken, R., Kearns, V., Wegener, A., Sheridan, C., Williams, R., Holz, F.G., and Eter, N.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Zelluläre Ersatzstrategien des RPE könnten durch Mitlieferung einer Zellträgermatrix verbessert werden. Wir untersuchten am Kaninchentiermodell 2 biostabile synthetische Substrate, welche sich durch Oberflächentopographie, Dicke, Steifheit and Porosität unterscheiden.[for full text, please go to the a.m. URL], 23. Jahrestagung der Retinologischen Gesellschaft

Published
2010
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121. Macular dystrophies mimicking age-related macular degeneration

Author

Saksens, N.T.M., Fleckenstein, M., Schmitz-Valckenberg, S., Holz, F.G., Hollander, A.I. den, Keunen, J.E.E., Boon, C.J.F., Hoyng, C.B., Saksens, N.T.M., Fleckenstein, M., Schmitz-Valckenberg, S., Holz, F.G., Hollander, A.I. den, Keunen, J.E.E., Boon, C.J.F., and Hoyng, C.B.

Abstract

Item does not contain fulltext, Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly population in the Western world. AMD is a clinically heterogeneous disease presenting with drusen, pigmentary changes, geographic atrophy and/or choroidal neovascularization. Due to its heterogeneous presentation, it can be challenging to distinguish AMD from several macular diseases that can mimic the features of AMD. This clinical overlap may potentially lead to misdiagnosis. In this review, we discuss the characteristics of AMD and the macular dystrophies that can mimic AMD. The appropriate use of clinical and genetic analysis can aid the clinician to establish the correct diagnosis, and to provide the patient with the appropriate prognostic information. An overview is presented of overlapping and distinguishing clinical features.

Published
2014

124. Central Areolar Choroidal Dystrophy (CACD) and Age-Related Macular Degeneration (AMD): Differentiating Characteristics in Multimodal Imaging

Author

Smailhodzic, D., Fleckenstein, M., Theelen, T., Boon, C.J.F., Huet, R.A. van, Ven, J.P. van de, Hollander, A.I. den, Schmitz-Valckenberg, S., Hoyng, C.B., Weber, B.H., Holz, F.G., Klevering, B.J., Smailhodzic, D., Fleckenstein, M., Theelen, T., Boon, C.J.F., Huet, R.A. van, Ven, J.P. van de, Hollander, A.I. den, Schmitz-Valckenberg, S., Hoyng, C.B., Weber, B.H., Holz, F.G., and Klevering, B.J.

Abstract

Contains fulltext : 97707.pdf (publisher's version ) (Closed access), Purpose. Late-onset central areolar choroidal dystrophy (CACD) may easily be confused with geographic atrophy (GA) in AMD. To detect discerning features, the morphologic changes in CACD patients and in AMD patients were assessed with confocal scanning laser ophthalmoscopy (cSLO), fundus autofluorescence (FAF), and spectral-domain optical coherence tomography (SD-OCT). Methods. A total of 30 CACD patients with identified PRPH2 gene mutations were analyzed and compared to 19 patients with early AMD and 13 patients with AMD-associated GA. The presence of drusen and pigment clumping was determined with color fundus photography. High-resolution in vivo imaging was performed with cSLO and SD-OCT. FAF images and SD-OCT volume scans were analyzed in each study eye. Results. On FAF, a speckled FAF pattern occurred significantly more often in CACD (85%) than in early AMD (5.6%; P < 0.0001). There was a significantly higher frequency of sub-RPE deposits in eyes with AMD than in eyes with CACD (36.8% versus 2.1% of scans, P = 0.0019). Reticular drusen could be visualized by SD-OCT and FAF imaging in 52.6% of the eyes with early AMD and in 100% of the eyes with GA, whereas this drusen phenotype did not manifest in eyes with CACD. Conclusions. Although outer retinal atrophy is the clinically common feature in advanced CACD as well as GA, there are microstructural alterations on high-resolution SD-OCT and FAF imaging that allow for the differentiation between CACD and AMD. The findings may help to identify patients in whom a diagnostic PRPH2 screening is warranted. (ClinicalTrials.gov number, NCT00393692.).

Published
2011

128. Epidemiologie

Author

Klaver, Caroline, Vingerling, Hans, Hofman, Bert, de Jong, PTVM (Paulus), Holz, F.G., Pauleikhoff, D., Ophthalmology, and Epidemiology

Published
1997

138. Characteristics and Spatial Distribution of Structural Features in Age-Related Macular Degeneration

Author

Saßmannshausen, Marlene, Behning, Charlotte, Weinz, Jonas, Goerdt, Lukas, Terheyden, Jan H., Chang, Petrus, Schmid, Matthias, Poor, Stephen H., Zakaria, Nadia, Finger, Robert P., Holz, Frank G., Pfau, Maximilian, Schmitz-Valckenberg, Steffen, Thiele, Sarah, Agostini, H., Altay, L., Atia, R., Bandello, F., Basile, P.G., Behning, C., Belmouhand, M., Berger, M., Binns, A., Boon, C.J.F., Böttger, M., Bouchet, C., Brazier, J.E., Butt, T., Carapezzi, C., Carlton, J., Carneiro, A., Charil, A., Coimbra, R., Cozzi, M., Crabb, D.P., Cunha-Vaz, J., Dahlke, C., de Sisternes, L., Dunbar, H., Finger, R.P., Fletcher, E., Floyd, H., Francisco, C., Gutfleisch, M., Hogg, R., Holz, F.G., Hoyng, C.B., Kilani, A., Krätzschmar, J., Kühlewein, L., Larsen, M., Leal, S., Lechanteur, Y.T.E., Luhmann, U.F.O., Lüning, A., Marques, I., Martinho, C., Montesano, G., Mulyukov, Z., Paques, M., Parodi, B., Parravano, M., Penas, S., Peters, T., Peto, T., Pfau, M., Poor, S., Priglinger, S., Rowen, D., Rubin, G.S., Sahel, J., Sánchez, C., Sander, O., Saßmannshausen, M., Schmid, M., Schmitz-Valckenberg, S., Schrinner-Fenske, H., Siedlecki, J., Silva, R., Skelly, A., Souied, E., Staurenghi, G., Stöhr, L., Taylor, D.J., Terheyden, J.H., Thiele, S., Tufail, A., Varano, M., Vieweg, L., Wintergerst, L., Wolf, A., and Zakaria, N.

Abstract

To report the prevalence and topographic distribution of structural characteristics in study participants with age-related macular degeneration (AMD) and controls in the cross-sectional study part of the MACUSTAR study (ClinicalTrials.govIdentifier: NCT03349801).

Published
2023
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141. Pharmacological Approaches to Age-Related Macular Degeneration.

Author

Krieglstein, Günther K., Weinreb, Robert N., Holz, Frank G., Spaide, Richard F., Eter, N., Krohne, T., and Holz, F.G.

Subjects
RETINAL degeneration, HUMAN heredity, DISEASES in older people, NEOVASCULARIZATION, ISOPENTENOIDS
Abstract

Based on the results of the ARED study, a prophylactic treatment with a combination of vitamin C, vitamin E, β-carotene, and zinc is recommended for patients meeting the fundoscopic criteria described as categories 3 and 4 in the study. For all other nutritional supplementation including lutein or zeaxanthin,which increase macular pigment density, there is as yet no proven efficacy with regard to the prevention of AMD. However, many new antiangiogenic therapies are currently under investigation in large multicentre trials and hold exciting potential for patients with neovascular AMD. Further insight into the angiogenic process and its inhibition may lead to more targets that may be transferred for use in patients with neovascular AMD. [ABSTRACT FROM AUTHOR]

Published
2005
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144. Versorgung von älteren Menschen mit neovaskulärer altersabhängiger Makuladegeneration.

Author

Finger, R.P. and Holz, F.G.

Abstract

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2012
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145. Grundlagen, Planung und Durchführung nichtkommerzieller klinischer Studien.

Author

Finger, R.P., Coch, C., Coenen, M., Mengel, M., Hartmann, G., and Holz, F.G.

Abstract

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2011
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146. Analyse eines ophthalmopathologischen Kollektivs humaner fetaler Augen unter besonderer Berücksichtigung außergewöhnlicher Befunde.

Author

Herwig, M.C., Müller, A.M., Holz, F.G., and Loeffler, K.U.

Abstract

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2010
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147. Bildgebende Diagnostik bei geographischer Atrophie.

Author

Fleckenstein, M., Wolf-Schnurrbusch, U., Wolf, S., Strachwitz, C., Holz, F.G., and Schmitz-Valckenberg, S.

Abstract

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2010
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148. Klinische Merkmale, Progression und Risikofaktoren bei geographischer Atrophie.

Author

Brinkmann, C.K., Adrion, C., Mansmann, U., Schmitz-Valckenberg, S., and Holz, F.G.

Abstract

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2010
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149. Therapieansätze bei geographischer Atrophie.

Author

Schmitz-Valckenberg, S., Mößner, A., Fleckenstein, M., Wiedemann, P., and Holz, F.G.

Abstract

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2010
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150. Konjunktivales Myxom - zwei Kasuistiken.

Author

Herwig, M.C., Fischer, H.P., Holz, F.G., and Loeffler, K.U.

Abstract

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2010
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