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11,764 results on '"Hodges, P"'

102. Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models

Author

Havel, Václav, Kruegel, Andrew C., Bechand, Benjamin, McIntosh, Scot, Stallings, Leia, Hodges, Alana, Wulf, Madalee G., Nelson, Mel, Hunkele, Amanda, Ansonoff, Michael, Pintar, John E., Hwu, Christopher, Ople, Rohini S., Abi-Gerges, Najah, Zaidi, Saheem A., Katritch, Vsevolod, Yang, Mu, Javitch, Jonathan A., Majumdar, Susruta, Hemby, Scott E., and Sames, Dalibor

Published
2024
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111. Defining key concepts for mental state attribution

Author

Quesque, François, Apperly, Ian, Baillargeon, Renée, Baron-Cohen, Simon, Becchio, Cristina, Bekkering, Harold, Bernstein, Daniel, Bertoux, Maxime, Bird, Geoffrey, Bukowski, Henryk, Burgmer, Pascal, Carruthers, Peter, Catmur, Caroline, Dziobek, Isabel, Epley, Nicholas, Erle, Thorsten Michael, Frith, Chris, Frith, Uta, Galang, Carl Michael, Gallese, Vittorio, Grynberg, Delphine, Happé, Francesca, Hirai, Masahiro, Hodges, Sara D., Kanske, Philipp, Kret, Mariska, Lamm, Claus, Nandrino, Jean Louis, Obhi, Sukhvinder, Olderbak, Sally, Perner, Josef, Rossetti, Yves, Schneider, Dana, Schurz, Matthias, Schuwerk, Tobias, Sebanz, Natalie, Shamay-Tsoory, Simone, Silani, Giorgia, Spaulding, Shannon, Todd, Andrew R., Westra, Evan, Zahavi, Dan, and Brass, Marcel

Published
2024
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115. The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer

Author

Amara, Chandra Sekhar, Kami Reddy, Karthik Reddy, Yuntao, Yang, Chan, Yuen San, Piyarathna, Danthasinghe Waduge Badrajee, Dobrolecki, Lacey Elizabeth, Shih, David J. H., Shi, Zhongcheng, Xu, Jun, Huang, Shixia, Ellis, Matthew J., Apolo, Andrea B., Ballester, Leomar Y., Gao, Jianjun, Hansel, Donna E., Lotan, Yair, Hodges, H. Courtney, Lerner, Seth P., Creighton, Chad J., Sreekumar, Arun, Zheng, W. Jim, Msaouel, Pavlos, Kavuri, Shyam M., and Putluri, Nagireddy

Published
2024
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124. Levi-spherical Schubert varieties

Author

Gao, Yibo, Hodges, Reuven, and Yong, Alexander

Subjects
Mathematics - Representation Theory, Mathematics - Algebraic Geometry, Mathematics - Combinatorics
Abstract

We prove a short, root-system uniform, combinatorial classification of Levi-spherical Schubert varieties for any generalized flag variety $G/B$ of finite Lie type. We apply this to the study of multiplicity-free decompositions of a Demazure module into irreducible representations of a Levi subgroup., Comment: 11 pages. Minor corrections made in v2. To appear in Advances in Mathematics

Published
2023
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125. Scaling NbTiN-based ac-powered Josephson digital to 400M devices/cm$^2$

Author

Herr, Anna, Herr, Quentin, Brebels, Steve, Kim, Min-Soo, Pokhrel, Ankit, Hodges, Blake, Josephsen, Trent, ONeal, Sabine, Bai, Ruiheng, Nowack, Katja, Valente-Feliciano, Anne-Marie, and Tökei, Zsolt

Subjects
Physics - Applied Physics
Abstract

We describe a fabrication stackup for digital logic with 16 superconducting NbTiN layers, self-shunted a-silicon barrier Josephson Junctions (JJs), and low loss, high-$\kappa$ tunable HZO capacitors. The stack enables 400 MJJ/cm$^2$ device density, efficient routing, and AC power distribution on a resonant network. The materials scale beyond 28nm lithography and are compatible with standard high-temperature CMOS processes. We report initial results for two-metal layer NbTiN wires with 50nm critical dimension. A semi-ascendance wire-and-via process module using 193i lithography and 50nm critical dimension has shown cross-section uniformity of 1%=1s across the 300mm wafer, critical temperature of 12.5K, and critical current of 0.1mA at 4.2K. We also present a new design of the resonant AC power network enabled by NbTiN wires and HZO MIM capacitors. The design matches the device density and provides a 30 GHz clock with estimated efficiency of up to 90%. Finally, magnetic imaging of patterned NbTiN ground planes shows low intrinsic defectivity and consistent trapping of vorteces in 0.5 mm holes spaced on a 20 $\mu$m x 20 $\mu$m grid., Comment: 7 pages, 3 figures

Published
2023

126. Disentangling centrality bias and final-state effects in the production of high-$p_T$ $\pi^0$ using direct $\gamma$ in $d$$+$Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV

Author

Abdulameer, N. J., Acharya, U., Aidala, C., Akiba, Y., Alfred, M., Aoki, K., Apadula, N., Ayuso, C., Babintsev, V., Barish, K. N., Bathe, S., Bazilevsky, A., Belmont, R., Berdnikov, A., Berdnikov, Y., Bichon, L., Blankenship, B., Blau, D. S., Boer, M., Bok, J. S., Borisov, V., Brooks, M. L., Bryslawskyj, J., Bumazhnov, V., Butler, C., Campbell, S., Roman, V. Canoa, Chiu, M., Connors, M., Corliss, R., Morales, Y. Corrales, Csanád, M., Csörgő, T., Liu, L. D., Danley, T. W., Daugherity, M. S., David, G., Dean, C. T., DeBlasio, K., Dehmelt, K., Denisov, A., Deshpande, A., Desmond, E. J., Doomra, V., Do, J. H., Drees, A., Drees, K. A., Dumancic, M., Durham, J. M., Durum, A., Elder, T., Enokizono, A., Esha, R., Fadem, B., Fan, W., Feege, N., Finger, Jr., M., Finger, M., Firak, D., Fitzgerald, D., Fokin, S. L., Frantz, J. E., Franz, A., Frawley, A. D., Fukuda, Y., Gal, C., Garg, P., Ge, H., Giles, M., Goto, Y., Grau, N., Greene, S. V., Gunji, T., Hachiya, T., Haggerty, J. S., Hahn, K. I., Han, S. Y., Harvey, M., Hasegawa, S., Haseler, T. O. S., Hemmick, T. K., He, X., Hill, K., Hodges, A., Homma, K., Hong, B., Hoshino, T., Hotvedt, N., Huang, J., Imrek, J., Inaba, M., Isenhower, D., Ito, Y., Ivanishchev, D., Jacak, B. V., Ji, Z., Johnson, B. M., Jorjadze, V., Jouan, D., Jumper, D. S., Kang, J. H., Kapukchyan, D., Karthas, S., Kazantsev, A. V., Khachatryan, V., Khanzadeev, A., Khatiwada, A., Kim, C., Kim, D. J., Kim, E. -J., Kim, M., Kim, M. H., Kim, T., Kincses, D., Kingan, A., Kistenev, E., Koblesky, T., Kotov, D., Kovacs, L., Kudo, S., Kurgyis, B., Kurita, K., Lajoie, J. G., Lallow, E. O., Larionova, D., Lebedev, A., Lee, S. H., Leitch, M. J., Leung, Y. H., Lewis, N. A., Lim, S. H., Liu, M. X., Li, X., Loggins, V. -R., Loomis, D. A., Lynch, D., Lökös, S., Majoros, T., Makek, M., Malaev, M., Manko, V. I., Mannel, E., Masuda, H., McCumber, M., McGlinchey, D., Mignerey, A. C., Mihalik, D. E., Milov, A., Mishra, D. K., Mitchell, J. T., Mitrankova, M., Mitrankov, Iu., Mitsuka, G., Mondal, M. M., Moon, T., Morrison, D. P., Morrow, S. I., Muhammad, A., Mulilo, B., Murakami, T., Murata, J., Nagai, K., Nagashima, K., Nagashima, T., Nagle, J. L., Nagy, M. I., Nakagawa, I., Nakagomi, H., Nakano, K., Nattrass, C., Nelson, S., Nouicer, R., Novitzky, N., Novotny, R., Novák, T., Nukazuka, G., Nyanin, A. S., O'Brien, E., Ogilvie, C. A., Oh, J., Koop, J. D. Orjuela, Orosz, M., Osborn, J. D., Oskarsson, A., Ozawa, K., Pantuev, V., Papavassiliou, V., Park, J. S., Park, S., Patel, M., Pate, S. F., Peng, W., Perepelitsa, D. V., Perera, G. D. N., PerezLara, C. E., Petti, R., Phipps, M., Pinkenburg, C., Potekhin, M., Pun, A., Purschke, M. L., Radzevich, P. V., Ramasubramanian, N., Read, K. F., Riabov, V., Riabov, Y., Richford, D., Rinn, T., Rosati, M., Rowan, Z., Runchey, J., Sakaguchi, T., Sako, H., Samsonov, V., Sarsour, M., Sato, K., Sato, S., Schaefer, B., Schmoll, B. K., Seidl, R., Sen, A., Seto, R., Sexton, A., Sharma, D., Shein, I., Shibata, M., Shibata, T. -A., Shigaki, K., Shimomura, M., Shi, Z., Silva, C. L., Silvermyr, D., Slunečka, M., Smith, K. L., Sorensen, S. P., Sourikova, I. V., Stankus, P. W., Stoll, S. P., Sugitate, T., Sukhanov, A., Sun, Z., Syed, S., Takahama, R., Takeda, A., Tanida, K., Tannenbaum, M. J., Tarafdar, S., Taranenko, A., Tarnai, G., Tieulent, R., Timilsina, A., Todoroki, T., Tomášek, M., Towell, C. L., Towell, R. S., Tserruya, I., Ueda, Y., Ujvari, B., van Hecke, H. W., Vazquez-Carson, S., Velkovska, J., Virius, M., Vrba, V., Wang, X. R., Wang, Z., Watanabe, Y., Wong, C. P., Xu, C., Xu, Q., Yamaguchi, Y. L., Yanovich, A., Yin, P., Yoon, I., Yoo, J. H., Yushmanov, I. E., Yu, H., Zajc, W. A., and Zou, L.

Subjects
Nuclear Experiment
Abstract

PHENIX presents a simultaneous measurement of the production of direct $\gamma$ and $\pi^0$ in $d$$+$Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV over a $p_T$ range of 7.5 to 18 GeV/$c$ for different event samples selected by event activity, i.e. charged-particle multiplicity detected at forward rapidity. Direct-photon yields are used to empirically estimate the contribution of hard-scattering processes in the different event samples. Using this estimate, the average nuclear-modification factor $R_{d\rm Au,EXP}^{\gamma^{\rm dir}}$ is $0.925{\pm}0.023({\rm stat}){\pm}0.15^{\rm (scale)}$, consistent with unity for minimum-bias (MB) $d$$+$Au events. For event classes with moderate event activity, $R_{d\rm Au,EXP}^{\gamma^{\rm dir}}$ is consistent with the MB value within 5\% uncertainty. These results confirm that the previously observed enhancement of high-$p_T$ $\pi^0$ production found in small-system collisions with low event activity is a result of a bias in interpreting event activity within the Glauber framework. In contrast, for the top 5\% of events with the highest event activity, $R_{d\rm Au,EXP}^{\gamma^{\rm dir}}$ is suppressed by 20\% relative to the MB value with a significance of $4.5\sigma$, which may be due to final-state effects., Comment: 279 authors from 69 institutions, 8 pages, 3 figures, v1 is version submitted to Physical Review Letters. HEPdata tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.html

Published
2023

127. Transverse single-spin asymmetry of charged hadrons at forward and backward rapidity in polarized $p$+$p$, $p$+Al, and $p$+Au collisions at $\sqrt{s_{NN}}=200$ GeV}

Author

Abdulameer, N. J., Acharya, U., Aidala, C., Akiba, Y., Alfred, M., Andrieux, V., Apadula, N., Asano, H., Azmoun, B., Babintsev, V., Bandara, N. S., Barish, K. N., Bathe, S., Bazilevsky, A., Beaumier, M., Belmont, R., Berdnikov, A., Berdnikov, Y., Bichon, L., Blankenship, B., Blau, D. S., Bok, J. S., Borisov, V., Brooks, M. L., Bryslawskyj, J., Bumazhnov, V., Campbell, S., Roman, V. Canoa, Cervantes, R., Chiu, M., Chi, C. Y., Choi, I. J., Choi, J. B., Citron, Z., Connors, M., Corliss, R., Morales, Y. Corrales, Cronin, N., Csanád, M., Csörgő, T., Danley, T. W., Daugherity, M. S., David, G., Dean, C. T., DeBlasio, K., Dehmelt, K., Denisov, A., Deshpande, A., Desmond, E. J., Dion, A., Dixit, D., Doomra, V., Do, J. H., Drees, A., Drees, K. A., Durham, J. M., Durum, A., En'yo, H., Enokizono, A., Esha, R., Fadem, B., Fan, W., Feege, N., Fields, D. E., Finger, Jr., M., Finger, M., Firak, D., Fitzgerald, D., Fokin, S. L., Frantz, J. E., Franz, A., Frawley, A. D., Fukuda, Y., Gallus, P., Gal, C., Garg, P., Ge, H., Giles, M., Giordano, F., Goto, Y., Grau, N., Greene, S. V., Perdekamp, M. Grosse, Gunji, T., Guragain, H., Hachiya, T., Haggerty, J. S., Hahn, K. I., Hamagaki, H., Hamilton, H. F., Hanks, J., Han, S. Y., Harvey, M., Hasegawa, S., Haseler, T. O. S., Hemmick, T. K., He, X., Hill, J. C., Hill, K., Hodges, A., Hollis, R. S., Homma, K., Hong, B., Hoshino, T., Hotvedt, N., Huang, J., Imai, K., Inaba, M., Iordanova, A., Isenhower, D., Ivanishchev, D., Jacak, B. V., Jezghani, M., Jiang, X., Ji, Z., Johnson, B. M., Jouan, D., Jumper, D. S., Kang, J. H., Kapukchyan, D., Karthas, S., Kawall, D., Kazantsev, A. V., Khachatryan, V., Khanzadeev, A., Khatiwada, A., Kim, C., Kim, E. -J., Kim, M., Kim, T., Kincses, D., Kingan, A., Kistenev, E., Klatsky, J., Kline, P., Koblesky, T., Kotov, D., Kovacs, L., Kudo, S., Kurgyis, B., Kurita, K., Kwon, Y., Lajoie, J. G., Larionova, D., Lebedev, A., Lee, S., Lee, S. H., Leitch, M. J., Leung, Y. H., Lewis, N. A., Lim, S. H., Liu, M. X., Li, X., Loggins, V. -R., Loomis, D. A., Lovasz, K., Lynch, D., Lökös, S., Majoros, T., Makdisi, Y. I., Makek, M., Manko, V. I., Mannel, E., McCumber, M., McGaughey, P. L., McGlinchey, D., McKinney, C., Mendoza, M., Mignerey, A. C., Milov, A., Mishra, D. K., Mitchell, J. T., Mitrankova, M., Mitrankov, Iu., Mitsuka, G., Miyasaka, S., Mizuno, S., Mondal, M. M., Montuenga, P., Moon, T., Morrison, D. P., Muhammad, A., Mulilo, B., Murakami, T., Murata, J., Nagai, K., Nagashima, K., Nagashima, T., Nagle, J. L., Nagy, M. I., Nakagawa, I., Nakano, K., Nattrass, C., Nelson, S., Niida, T., Nouicer, R., Novitzky, N., Novák, T., Nukazuka, G., Nyanin, A. S., O'Brien, E., Ogilvie, C. A., Oh, J., Koop, J. D. Orjuela, Orosz, M., Osborn, J. D., Oskarsson, A., Ottino, G. J., Ozawa, K., Pantuev, V., Papavassiliou, V., Park, J. S., Park, S., Patel, M., Pate, S. F., Peng, W., Perepelitsa, D. V., Perera, G. D. N., Peressounko, D. Yu., PerezLara, C. E., Perry, J., Petti, R., Phipps, M., Pinkenburg, C., Pisani, R. P., Potekhin, M., Pun, A., Purschke, M. L., Radzevich, P. V., Ramasubramanian, N., Read, K. F., Reynolds, D., Riabov, V., Riabov, Y., Richford, D., Rinn, T., Rolnick, S. D., Rosati, M., Rowan, Z., Runchey, J., Safonov, A. S., Sakaguchi, T., Sako, H., Samsonov, V., Sarsour, M., Sato, S., Schaefer, B., Schmoll, B. K., Sedgwick, K., Seidl, R., Sen, A., Seto, R., Sexton, A., Sharma, D., Shein, I., Shibata, M., Shibata, T. -A., Shigaki, K., Shimomura, M., Shioya, T., Shi, Z., Shukla, P., Sickles, A., Silva, C. L., Silvermyr, D., Singh, B. K., Singh, C. P., Singh, V., Slunečka, M., Smith, K. L., Snowball, M., Soltz, R. A., Sondheim, W. E., Sorensen, S. P., Sourikova, I. V., Stankus, P. W., Stoll, S. P., Sugitate, T., Sukhanov, A., Sumita, T., Sun, J., Sun, Z., Sziklai, J., Takahama, R., Tanida, K., Tannenbaum, M. J., Tarafdar, S., Taranenko, A., Tarnai, G., Tieulent, R., Timilsina, A., Todoroki, T., Tomášek, M., Towell, C. L., Towell, R. S., Tserruya, I., Ueda, Y., Ujvari, B., van Hecke, H. W., Velkovska, J., Virius, M., Vrba, V., Vukman, N., Wang, X. R., Wang, Z., Watanabe, Y. S., Wong, C. P., Woody, C. L., Xue, L., Xu, C., Xu, Q., Yalcin, S., Yamaguchi, Y. L., Yamamoto, H., Yanovich, A., Yoon, I., Yoo, J. H., Yushmanov, I. E., Yu, H., Zajc, W. A., Zelenski, A., and Zou, L.

Subjects
High Energy Physics - Experiment
Abstract

Reported here are transverse single-spin asymmetries ($A_{N}$) in the production of charged hadrons as a function of transverse momentum ($p_T$) and Feynman-$x$ ($x_F$) in polarized $p^{\uparrow}$+$p$, $p^{\uparrow}$+Al, and $p^{\uparrow}$+Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV. The measurements have been performed at forward and backward rapidity ($1.4<|\eta|<2.4$) over the range of $1.50$) in $p^{\uparrow}$+$p$ collisions, whereas the $p^{\uparrow}$+Al and $p^{\uparrow}$+Au results show smaller asymmetries. This finding provides new opportunities to investigate the origin of transverse single-spin asymmetries and a tool to study nuclear effects in $p$+$A$ collisions., Comment: 322 authors from 70 institutions, 13 pages, 9 figures, 13 tables, one appendix, 2015 data. v2 is version accepted for publication in Phys. Rev. D. HEPData tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.html

Published
2023
Full Text
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128. Transverse single-spin asymmetry of midrapidity $\pi^{0}$ and $\eta$ mesons in $p$+Au and $p$+Al collisions at $\sqrt{s_{_{NN}}}=$ 200 GeV

Author

Abdulameer, N. J., Acharya, U., Aidala, C., Akiba, Y., Alfred, M., Andrieux, V., Apadula, N., Asano, H., Azmoun, B., Babintsev, V., Bandara, N. S., Barish, K. N., Bathe, S., Bazilevsky, A., Beaumier, M., Belmont, R., Berdnikov, A., Berdnikov, Y., Bichon, L., Blankenship, B., Blau, D. S., Bok, J. S., Borisov, V., Brooks, M. L., Bryslawskyj, J., Bumazhnov, V., Campbell, S., Roman, V. Canoa, Cervantes, R., Chiu, M., Chi, C. Y., Choi, I. J., Choi, J. B., Citron, Z., Connors, M., Corliss, R., Morales, Y. Corrales, Cronin, N., Csanád, M., Csörgő, T., Danley, T. W., Daugherity, M. S., David, G., Dean, C. T., DeBlasio, K., Dehmelt, K., Denisov, A., Deshpande, A., Desmond, E. J., Dion, A., Dixit, D., Doomra, V., Do, J. H., Drees, A., Drees, K. A., Durham, J. M., Durum, A., En'yo, H., Enokizono, A., Esha, R., Fadem, B., Fan, W., Feege, N., Fields, D. E., Finger, Jr., M., Finger, M., Firak, D., Fitzgerald, D., Fokin, S. L., Frantz, J. E., Franz, A., Frawley, A. D., Fukuda, Y., Gallus, P., Gal, C., Garg, P., Ge, H., Giles, M., Giordano, F., Goto, Y., Grau, N., Greene, S. V., Perdekamp, M. Grosse, Gunji, T., Guragain, H., Hachiya, T., Haggerty, J. S., Hahn, K. I., Hamagaki, H., Hamilton, H. F., Hanks, J., Han, S. Y., Harvey, M., Hasegawa, S., Haseler, T. O. S., Hemmick, T. K., He, X., Hill, J. C., Hill, K., Hodges, A., Hollis, R. S., Homma, K., Hong, B., Hoshino, T., Hotvedt, N., Huang, J., Imai, K., Inaba, M., Iordanova, A., Isenhower, D., Ivanishchev, D., Jacak, B. V., Jezghani, M., Jiang, X., Ji, Z., Johnson, B. M., Jouan, D., Jumper, D. S., Kang, J. H., Kapukchyan, D., Karthas, S., Kawall, D., Kazantsev, A. V., Khachatryan, V., Khanzadeev, A., Khatiwada, A., Kim, C., Kim, E. -J., Kim, M., Kim, T., Kincses, D., Kingan, A., Kistenev, E., Klatsky, J., Kline, P., Koblesky, T., Kotov, D., Kovacs, L., Kudo, S., Kurgyis, B., Kurita, K., Kwon, Y., Lajoie, J. G., Larionova, D., Lebedev, A., Lee, S., Lee, S. H., Leitch, M. J., Leung, Y. H., Lewis, N. A., Lim, S. H., Liu, M. X., Li, X., Loggins, V. -R., Loomis, D. A., Lovasz, K., Lynch, D., Lökös, S., Majoros, T., Makdisi, Y. I., Makek, M., Manko, V. I., Mannel, E., McCumber, M., McGaughey, P. L., McGlinchey, D., McKinney, C., Mendoza, M., Mignerey, A. C., Milov, A., Mishra, D. K., Mitchell, J. T., Mitrankova, M., Mitrankov, Iu., Mitsuka, G., Miyasaka, S., Mizuno, S., Mondal, M. M., Montuenga, P., Moon, T., Morrison, D. P., Muhammad, A., Mulilo, B., Murakami, T., Murata, J., Nagai, K., Nagashima, K., Nagashima, T., Nagle, J. L., Nagy, M. I., Nakagawa, I., Nakano, K., Nattrass, C., Nelson, S., Niida, T., Nouicer, R., Novitzky, N., Novák, T., Nukazuka, G., Nyanin, A. S., O'Brien, E., Ogilvie, C. A., Oh, J., Koop, J. D. Orjuela, Orosz, M., Osborn, J. D., Oskarsson, A., Ottino, G. J., Ozawa, K., Pantuev, V., Papavassiliou, V., Park, J. S., Park, S., Patel, M., Pate, S. F., Peng, W., Perepelitsa, D. V., Perera, G. D. N., Peressounko, D. Yu., PerezLara, C. E., Perry, J., Petti, R., Phipps, M., Pinkenburg, C., Pisani, R. P., Potekhin, M., Pun, A., Purschke, M. L., Radzevich, P. V., Ramasubramanian, N., Read, K. F., Reynolds, D., Riabov, V., Riabov, Y., Richford, D., Rinn, T., Rolnick, S. D., Rosati, M., Rowan, Z., Runchey, J., Safonov, A. S., Sakaguchi, T., Sako, H., Samsonov, V., Sarsour, M., Sato, S., Schaefer, B., Schmoll, B. K., Sedgwick, K., Seidl, R., Sen, A., Seto, R., Sexton, A., Sharma, D., Shein, I., Shibata, M., Shibata, T. -A., Shigaki, K., Shimomura, M., Shioya, T., Shi, Z., Shukla, P., Sickles, A., Silva, C. L., Silvermyr, D., Singh, B. K., Singh, C. P., Singh, V., Slunečka, M., Smith, K. L., Snowball, M., Soltz, R. A., Sondheim, W. E., Sorensen, S. P., Sourikova, I. V., Stankus, P. W., Stoll, S. P., Sugitate, T., Sukhanov, A., Sumita, T., Sun, J., Sun, Z., Sziklai, J., Takahama, R., Tanida, K., Tannenbaum, M. J., Tarafdar, S., Taranenko, A., Tarnai, G., Tieulent, R., Timilsina, A., Todoroki, T., Tomášek, M., Towell, C. L., Towell, R. S., Tserruya, I., Ueda, Y., Ujvari, B., van Hecke, H. W., Velkovska, J., Virius, M., Vrba, V., Vukman, N., Wang, X. R., Wang, Z., Watanabe, Y. S., Wong, C. P., Woody, C. L., Xue, L., Xu, C., Xu, Q., Yalcin, S., Yamaguchi, Y. L., Yamamoto, H., Yanovich, A., Yoon, I., Yoo, J. H., Yushmanov, I. E., Yu, H., Zajc, W. A., Zelenski, A., and Zou, L.

Subjects
High Energy Physics - Experiment
Abstract

Presented are the first measurements of the transverse single-spin asymmetries ($A_N$) for neutral pions and eta mesons in $p$+Au and $p$+Al collisions at $\sqrt{s_{_{NN}}}=200$ GeV in the pseudorapidity range $|\eta|<$0.35 with the PHENIX detector at the Relativistic Heavy Ion Collider. The asymmetries are consistent with zero, similar to those for midrapidity neutral pions and eta mesons produced in $p$+$p$ collisions. These measurements show no evidence of additional effects that could potentially arise from the more complex partonic environment present in proton-nucleus collisions., Comment: 322 authors from 70 institutions, 8 pages, 2 figures, 1 table, 2015 data. v2 is version accepted for publication in Phys. Rev. D. HEPData tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.html

Published
2023

129. PyGenStability: Multiscale community detection with generalized Markov Stability

Author

Arnaudon, Alexis, Schindler, Dominik J., Peach, Robert L., Gosztolai, Adam, Hodges, Maxwell, Schaub, Michael T., and Barahona, Mauricio

Subjects
Computer Science - Social and Information Networks, Computer Science - Mathematical Software, G.4, I.5.3
Abstract

We present PyGenStability, a general-use Python software package that provides a suite of analysis and visualisation tools for unsupervised multiscale community detection in graphs. PyGenStability finds optimized partitions of a graph at different levels of resolution by maximizing the generalized Markov Stability quality function with the Louvain or Leiden algorithms. The package includes automatic detection of robust graph partitions and allows the flexibility to choose quality functions for weighted undirected, directed and signed graphs, and to include other user-defined quality functions.

Published
2023
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130. The Present and Future of QCD

Author

Achenbach, P., Adhikari, D., Afanasev, A., Afzal, F., Aidala, C. A., Al-bataineh, A., Almaalol, D. K., Amaryan, M., Androić, D., Armstrong, W. R., Arratia, M., Arrington, J., Asaturyan, A., Aschenauer, E. C., Atac, H., Avakian, H., Averett, T., Gayoso, C. Ayerbe, Bai, X., Barish, K. N., Barnea, N., Basar, G., Battaglieri, M., Baty, A. A., Bautista, I., Bazilevsky, A., Beattie, C., Behera, S. C., Bellini, V., Bellwied, R., Benesch, J. F., Benmokhtar, F., Bernardes, C. A., Bernauer, J. C., Bhatt, H., Bhatta, S., Boer, M., Boettcher, T. J., Bogacz, S. A., Bossi, H. J., Brandenburg, J. D., Brash, E. J., Briceño, R. A., Briscoe, W. J., Brodsky, S. J., Brown, D. A., Burkert, V. D., Caines, H., Cali, I. A., Camsonne, A., Carman, D. S., Caylor, J., Cerci, S., Llatas, M. Chamizo, Chatterjee, S., Chen, J. P., Chen, Y., Chen, Y. -C., Chien, Y. -T., Chou, P. -C., Chu, X., Chudakov, E., Cline, E., Cloët, I. C., Cole, P. L., Connors, M. E., Constantinou, M., Cosyn, W., Dusa, S. Covrig, Cruz-Torres, R., D'Alesio, U., da Silva, C., Davoudi, Z., Dean, C. T., Dean, D. J., Demarteau, M., Deshpande, A., Detmold, W., Deur, A., Devkota, B. R., Dhital, S., Diefenthaler, M., Dobbs, S., Döring, M., Dong, X., Dotel, R., Dow, K. A., Downie, E. J., Drachenberg, J. L., Dumitru, A., Dunlop, J. C., Dupre, R., Durham, J. M., Dutta, D., Edwards, R. G., Ehlers, R. J., Fassi, L. El, Elaasar, M., Elouadrhiri, L., Engelhardt, M., Ent, R., Esumi, S., Evdokimov, O., Eyser, O., Fanelli, C., Fatemi, R., Fernando, I. P., Flor, F. A., Fomin, N., Frawley, A. D., Frederico, T., Fries, R. J., Gal, C., Gamage, B. R., Gamberg, L., Gao, H., Gaskell, D., Geurts, F., Ghandilyan, Y., Ghimire, N., Gilman, R., Gleason, C., Gnanvo, K., Gothe, R. W., Greene, S. V., Grießhammer, H. W., Grossberndt, S. K., Grube, B., Hackett, D. C., Hague, T. J., Hakobyan, H., Hansen, J. -O., Hatta, Y., Hattawy, M., Havener, L. B., Hen, O., Henry, W., Higinbotham, D. W., Hobbs, T. J., Hodges, A. M., Holmstrom, T., Hong, B., Horn, T., Howell, C. R., Huang, H. Z., Huang, M., Huang, S., Huber, G. M., Hyde, C. E., Isupov, E. L., Jacobs, P. M., Jalilian-Marian, J., Jentsch, A., Jheng, H., Ji, C. -R., Ji, X., Jia, J., Jones, D. C., Jones, M. K., Kalantarians, N., Kalicy, G., Kang, Z. B., Karthein, J. M., Keller, D., Keppel, C., Khachatryan, V., Kharzeev, D. E., Kim, H., Kim, M., Kim, Y., King, P. M., Kinney, E., Klein, S. R., Ko, H. S., Koch, V., Kohl, M., Kovchegov, Y. V., Krintiras, G. K., Kubarovsky, V., Kuhn, S. E., Kumar, K. S., Kutz, T., Lajoie, J. G., Lauret, J., Lavrukhin, I., Lawrence, D., Lee, J. H., Lee, K., Lee, S., Lee, Y. -J., Li, S., Li, W., Li, Xiaqing, Li, Xuan, Liao, J., Lin, H. -W., Lisa, M. A., Liu, K. -F., Liu, M. X., Liu, T., Liuti, S., Liyanage, N., Llope, W. J., Loizides, C., Longo, R., Lorenzon, W., Lunkenheimer, S., Luo, X., Ma, R., McKinnon, B., Meekins, D. G., Mehtar-Tani, Y., Melnitchouk, W., Metz, A., Meyer, C. A., Meziani, Z. -E., Michaels, R., Michel, J. K. L., Milner, R. G., Mkrtchyan, H., Mohanmurthy, P., Mohanty, B., Mokeev, V. I., Moon, D. H., Mooney, I. A., Morningstar, C., Morrison, D. P., Müller, B., Mukherjee, S., Mulligan, J., Camacho, C. Munoz, Quijada, J. A. Murillo, Murray, M. J., Nadeeshani, S. A., Nadel-Turonski, P., Nam, J. D., Nattrass, C. E., Nijs, G., Noronha, J., Noronha-Hostler, J., Novitzky, N., Nycz, M., Olness, F. I., Osborn, J. D., Pak, R., Pandey, B., Paolone, M., Papandreou, Z., Paquet, J. -F., Park, S., Paschke, K. D., Pasquini, B., Pasyuk, E., Patel, T., Patton, A., Paudel, C., Peng, C., Peng, J. C., Da Costa, H. Pereira, Perepelitsa, D. V., Peters, M. J., Petreczky, P., Pisarski, R. D., Pitonyak, D., Ploskon, M. A., Posik, M., Poudel, J., Pradhan, R., Prokudin, A., Pruneau, C. A., Puckett, A. J. R., Pujahari, P., Putschke, J., Pybus, J. R., Qiu, J. -W., Rajagopal, K., Ratti, C., Read, K. F., Reed, R., Richards, D. G., Riedl, C., Ringer, F., Rinn, T., West, J. Rittenhouse, Roche, J., Rodas, A., Roland, G., Romero-López, F., Rossi, P., Rostomyan, T., Ruan, L., Ruimi, O. M., Saha, N. R., Sahoo, N. R., Sakaguchi, T., Salazar, F., Salgado, C. W., Salmè, G., Salur, S., Santiesteban, S. N., Sargsian, M. M., Sarsour, M., Sato, N., Satogata, T., Sawada, S., Schäfer, T., Scheihing-Hitschfeld, B., Schenke, B., Schindler, S. T., Schmidt, A., Seidl, R., Shabestari, M. H., Shanahan, P. E., Shen, C., Sheng, T. -A., Shepherd, M. R., Sickles, A. M., Sievert, M. D., Smith, K. L., Song, Y., Sorensen, A., Souder, P. A., Sparveris, N., Srednyak, S., Leiton, A. G. Stahl, Stasto, A. M., Steinberg, P., Stepanyan, S., Stephanov, M., Stevens, J. R., Stewart, D. J., Stewart, I. W., Stojanovic, M., Strakovsky, I., Strauch, S., Strickland, M., Cerci, D. Sunar, Suresh, M., Surrow, B., Syritsyn, S., Szczepaniak, A. P., Tadepalli, A. S., Tang, A. H., Takaki, J. D. Tapia, Tarnowsky, T. J., Tawfik, A. N., Taylor, M. I., Tennant, C., Thiel, A., Thomas, D., Tian, Y., Timmins, A. R., Tribedy, P., Tu, Z., Tuo, S., Ullrich, T., Umaka, E., Upton, D. W., Vary, J. P., Velkovska, J., Venugopalan, R., Vijayakumar, A., Vitev, I., Vogelsang, W., Vogt, R., Vossen, A., Voutier, E., Vovchenko, V., Walker-Loud, A., Wang, F., Wang, J., Wang, X., Wang, X. -N., Weinstein, L. B., Wenaus, T. J., Weyhmiller, S., Wissink, S. W., Wojtsekhowski, B., Wong, C. P., Wood, M. H., Wunderlich, Y., Wyslouch, B., Xiao, B. W., Xie, W., Xiong, W., Xu, N., Xu, Q. H., Xu, Z., Yaari, D., Yao, X., Ye, Z., Ye, Z. H., Yero, C., Yuan, F., Zajc, W. A., Zhang, C., Zhang, J., Zhao, F., Zhao, Y., Zhao, Z. W., Zheng, X., Zhou, J., and Zurek, M.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment, Nuclear Experiment, Nuclear Theory
Abstract

This White Paper presents the community inputs and scientific conclusions from the Hot and Cold QCD Town Meeting that took place September 23-25, 2022 at MIT, as part of the Nuclear Science Advisory Committee (NSAC) 2023 Long Range Planning process. A total of 424 physicists registered for the meeting. The meeting highlighted progress in Quantum Chromodynamics (QCD) nuclear physics since the 2015 LRP (LRP15) and identified key questions and plausible paths to obtaining answers to those questions, defining priorities for our research over the coming decade. In defining the priority of outstanding physics opportunities for the future, both prospects for the short (~ 5 years) and longer term (5-10 years and beyond) are identified together with the facilities, personnel and other resources needed to maximize the discovery potential and maintain United States leadership in QCD physics worldwide. This White Paper is organized as follows: In the Executive Summary, we detail the Recommendations and Initiatives that were presented and discussed at the Town Meeting, and their supporting rationales. Section 2 highlights major progress and accomplishments of the past seven years. It is followed, in Section 3, by an overview of the physics opportunities for the immediate future, and in relation with the next QCD frontier: the EIC. Section 4 provides an overview of the physics motivations and goals associated with the EIC. Section 5 is devoted to the workforce development and support of diversity, equity and inclusion. This is followed by a dedicated section on computing in Section 6. Section 7 describes the national need for nuclear data science and the relevance to QCD research., Comment: QCD Town Meeting White Paper, as submitted to 2023 NSAC LRP committee on Feb. 28, 2023

Published
2023
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131. Optical Memory, Switching, and Neuromorphic Functionality in Metal Halide Perovskite Materials and Devices

Author

Vats, Gaurav, Hodges, Brett, Ferguson, Andrew J., Wheeler, Lance, and Blackburn, Jeffrey L.

Subjects
Physics - Applied Physics, Condensed Matter - Materials Science
Abstract

Metal halide perovskite-based materials have emerged over the past few decades as remarkable solution-processable opto-electronic materials with many intriguing properties and potential applications. These emerging materials have recently been considered for their promise in low-energy memory and information processing applications. In particular, their large optical cross-sections, high photoconductance contrast, large carrier diffusion lengths, and mixed electronic/ionic transport mechanisms are attractive for enabling memory elements and neuromorphic devices that are written and/or read in the optical domain. Here, we review recent progress toward memory and neuromorphic functionality in metal halide perovskite materials and devices where photons are used as a critical degree of freedom for switching, memory, and neuromorphic functionality.

Published
2023
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132. Religious leaders’ nuanced views on birth spacing and contraceptives in Sierra Leone - qualitative insights

Author

Regina Mamidy Yillah, Florence Bull, Alhaji Sawaneh, Beryl Reindorf, Hamid Turay, Haja Ramatulai Wurie, Mary Hamer Hodges, and Augustus Osborne

Subjects
Birth spacing, Family planning, Religious, Leaders, Sierra Leone, Gynecology and obstetrics, RG1-991
Abstract

Abstract Background Sierra Leone is a religiously diverse country, with Christianity and Islam being the dominant faiths. This religious landscape plays a significant role in shaping attitudes towards family planning and contraceptives. We examined religious leaders’ knowledge of family planning and modern contraceptive methods. Methods In September 2021, data was collected from 116 religious leaders in Sierra Leone, including 32 Muslims and 84 Christians from nine different denominations from sixteen districts, through 16 focus group discussions. The data was subjected to a thematic analysis using NVIVO 12 software. Results The study found a spectrum of opinions among religious leaders, both between religions (Christianity vs. Islam) and within denominations of Christianity. There was a general acceptance of natural birth spacing methods, like abstinence during fertile periods, across both Christian and Muslim leaders. Views on modern contraceptives were more divided. Catholics generally opposed them, citing religious doctrines against interfering with procreation. Pentecostals and some Muslims, however, found them permissible under certain circumstances, like promoting family well-being or spacing births for health reasons. Conclusion The study reveals that religious leaders’ views on family planning in Sierra Leone are multifaceted. Understanding these nuances is crucial for designing effective family planning programs. By working with denominations that are more accepting of modern methods and leveraging the support for natural birth spacing methods across religions, there’s potential to improve reproductive health outcomes in Sierra Leone.

Published
2024
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133. Fracture resistance of CAD/CAM provisional crowns with two different designs: an in vitro study

Author

Salwa Mekled, Mark Iskander, Belinda Rodriguez, Paige Hodges, Jasleen Bhogal, Joan Adechoubou, and Geraldine Weinstein

Subjects
crown, overlay, indirect restorations, fracture, Other systems of medicine, RZ201-999
Abstract

Aim: To evaluate the fracture resistance of printed crowns with two different designs. Methods: Forty restorations (n = 20/group) were fabricated using resin matrix ceramic (VarseoSmileTM) with different designs as follows: group 1: overlay restoration with chamfer margin; group 2: overlay restoration with chamfer margin located 3 mm above the gingiva. Restorations were bonded to resin dies using 3M RelyX Luting Cement. Compression forces were applied with a 4 mm diameter steel bar at the midline fissure of each crown using the universal testing machine. Restorations were loaded until fracture, and fracture resistance at maximum load was recorded. Statistical analysis: A t-test was used for statistical comparison between groups. Results: No difference in the fracture resistance was detected for both groups. Conclusions: Different designs of composite resin crowns fabricated using CAD/CAM techniques can be used, however further research is needed to assess the clinical outcomes.

Published
2024
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134. Deepening mechanisms of cut-off lows in the Southern Hemisphere and the role of jet streams: insights from eddy kinetic energy analysis

Author

H. R. Pinheiro, K. I. Hodges, and M. A. Gan

Subjects
Meteorology. Climatology, QC851-999
Abstract

Cut-off lows (COLs) exhibit diverse structures and lifecycles, ranging from confined upper-tropospheric systems to deep, multi-level vortex structures. While COL climatologies are well documented, the mechanisms driving their deepening remain unclear. To bridge this gap, a novel track matching algorithm applied to ERA-Interim reanalysis investigates the vertical extent of Southern Hemisphere COLs. Composite analysis based on structure and eddy kinetic energy budget differentiates four COL categories: shallow, deep, weak, and strong, revealing similarities and disparities. Deep, strong COLs concentrate around Australia and the southwestern Pacific, peaking in autumn and spring, while shallow, weak COLs are more common in summer and closer to the Equator. Despite their differences, both contrasting types evolve energetically via anticyclonic Rossby wave breaking. The distinct roles of jet streams in affecting COL types are addressed: intense polar front jets correlate with more deep COLs, whereas stronger subtropical jets relate to fewer shallow COLs. The COL deepening typically occurs in the presence of a robust upstream polar front jet, which enhances ageostrophic flux convergence and baroclinic processes. The subtropical jet positively correlates with COL intensity but weakens when considering the seasonality, suggesting uncertainties in this relationship. Additionally, we highlight the significance of diabatic processes in COL deepening, addressing their misrepresentation in reanalysis and emphasizing the need for more observational and modelling studies to refine the energetic framework.

Published
2024
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135. The risk of synoptic-scale Arctic cyclones to shipping

Author

A. F. Vessey, K. I. Hodges, L. C. Shaffrey, and J. J. Day

Subjects
Environmental technology. Sanitary engineering, TD1-1066, Geography. Anthropology. Recreation, Environmental sciences, GE1-350, Geology, QE1-996.5
Abstract

The risk posed by Arctic cyclones to ships has seldom been quantified due to the lack of publicly available historical Arctic ship track data. This study investigates Arctic ship tracks derived from automatic identification system (AIS) transponders from September 2009 to December 2016. These are analysed with historical synoptic-scale cyclone tracks derived from ERA-5 reanalysis data and reports of past Arctic shipping incidents. We determine the number of ship tracks that intersected with intense Arctic cyclones tracks and how many of these intersections resulted in a reported shipping incident. The number of ships operating in the Arctic has increased year-on-year from 2010 to 2016. The highest density of ships occurs year-round in the Barents Sea. Trans-Arctic shipping transits via the Northern Sea Route and the Northwest Passage are limited to summer and autumn months, when sea ice extent has retreated sufficiently from the coastlines. Ship track density along these trans-Arctic routes is far less than the thousands of ships travelling in the Barents Sea year-round. Between 2010 and 2016, 158 Arctic shipping incidents were reported, but only 6 % of these reported incidents occurred following the passage of an intense Arctic cyclone. Arctic cyclones with significant wave heights greater than 6 m are found to frequently intersect ships, but only 0.1 % of these intersections resulted in a reported shipping incident. Results from this study indicate that ships are frequently impacted by Arctic cyclones, but cyclones were not a dominant cause of reported Arctic shipping incidents between 2010 and 2016. This suggests that ships are resilient to the rough sea conditions that past Arctic cyclones have caused, therefore mitigating and reducing risk.

Published
2024
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136. Evaluation of the hyperspectral radiometer (HSR1) at the Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) site

Author

K. A. Balmes, L. D. Riihimaki, J. Wood, C. Flynn, A. Theisen, M. Ritsche, L. Ma, G. B. Hodges, and C. Herrera

Subjects
Environmental engineering, TA170-171, Earthwork. Foundations, TA715-787
Abstract

The Peak Design Ltd hyperspectral radiometer (HSR1) was tested at the Atmospheric Radiation Measurement (ARM) user facility Southern Great Plains (SGP) site in Lamont, Oklahoma, for 2 months from May to July 2022. The HSR1 is a prototype instrument that measures total (Ftotal) and diffuse (Fdiffuse) spectral irradiance from 360 to 1100 nm with a spectral resolution of 3 nm. The HSR1 spectral irradiance measurements are compared to nearby collocated spectral radiometers, including two multifilter rotating shadowband radiometers (MFRSRs) and the Shortwave Array Spectroradiometer–Hemispheric (SASHe) radiometer. The Ftotal at 500 nm for the HSR1 compared to the MFRSRs has a mean (relative) difference of 0.01 W m−2 nm−1 (1 %–2 %). The HSR1 mean Fdiffuse at 500 nm is smaller than the MFRSRs' by 0.03–0.04 (10 %) W m−2 nm−1. The HSR1 clear-sky aerosol optical depth (AOD) is also retrieved by considering Langley regressions and compared to collocated instruments such as the Cimel sunphotometer (CSPHOT), MFRSRs, and SASHe. The mean HSR1 AOD at 500 nm is larger than the CSPHOT's by 0.010 (8 %) and larger than the MFRSRs' by 0.007–0.017 (6 %–18 %). In general, good agreement between the HSR1 and other instruments is found in terms of the Ftotal, Fdiffuse, and AODs at 500 nm. The HSR1 quantities are also compared at other wavelengths to the collocated instruments. The comparisons are within ∼ 10 % for the Ftotal and Fdiffuse, except for 940 nm, where there is relatively larger disagreement. The AOD comparisons are within ∼ 10 % at 415 and 440 nm; however, a relatively larger disagreement in the AOD comparison is found for higher wavelengths.

Published
2024
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137. Conversations about Sexual and Reproductive Health and Rights--From a School Nurse Perspective

Author

Silivri, Martina, Wirf, Therese, Hodges, Eric A., Fredholm, Ylva S., and Björk, Maria

Abstract

Students have the right to receive education about sexual and reproductive health and rights (SRHR). The United Nations Agenda 2030 for sustainable development includes goals regarding SRHR, including the right to universal access to sexual and reproductive health care services and gender equality. The study used a qualitative design with an inductive approach. Data were collected through semistructured interviews. The results are presented in three categories and nine subcategories. The categories were "having an open attitude," "organizational prerequisites," and "challenging tasks." An open attitude was required to create confidence for both school nurses and students in SRHR conversations. Organizational prerequisites, such as planning SRHR education with others, were successful. Multicultural meetings and conversations regarding gender identity and sexual orientation were challenging tasks. Increased knowledge of SRHR and national standardized guidelines are suggested to achieve Agenda 2030 SRHR goals and to ensure equity in school health care.

Published
2023
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140. Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias

Author

Kaivola, Karri, Chia, Ruth, Ding, Jinhui, Rasheed, Memoona, Fujita, Masashi, Menon, Vilas, Walton, Ronald L, Collins, Ryan L, Billingsley, Kimberley, Brand, Harrison, Talkowski, Michael, Zhao, Xuefang, Dewan, Ramita, Stark, Ali, Ray, Anindita, Solaiman, Jerez, Pilar Alvarez, Malik, Laksh, Dawson, Ted M, Rosenthal, Liana S, Albert, Marilyn S, Pletnikova, Olga, Troncoso, Juan C, Masellis, Mario, Keith, Julia, Black, Sandra E, Ferrucci, Luigi, Resnick, Susan M, Tanaka, Toshiko, Soltis, Anthony R, Viollet, Coralie, Sukumar, Gauthaman, Alba, Camille, Lott, Nathaniel, Martinez, Elisa McGrath, Tuck, Meila, Singh, Jatinder, Bacikova, Dagmar, Zhang, Xijun, Hupalo, Daniel N, Adeleye, Adelani, Wilkerson, Matthew D, Pollard, Harvey B, Dalgard, Clifton L, Gan-Or, Ziv, Rogaeva, Ekaterina, Brice, Alexis, Lesage, Suzanne, Xiromerisiou, Georgia, Calvo, Andrea, Canosa, Antonio, Chio, Adriano, Logroscino, Giancarlo, Mora, Gabriele, Krüger, Reijko, May, Patrick, Alcolea, Daniel, Clarimon, Jordi, Fortea, Juan, Gonzalez-Aramburu, Isabel, Infante, Jon, Lage, Carmen, Lleó, Alberto, Pastor, Pau, Sanchez-Juan, Pascual, Brett, Francesca, Aarsland, Dag, Al-Sarraj, Safa, Attems, Johannes, Gentleman, Steve, Hardy, John A, Hodges, Angela K, Love, Seth, McKeith, Ian G, Morris, Christopher M, Morris, Huw R, Palmer, Laura, Pickering-Brown, Stuart, Ryten, Mina, Thomas, Alan J, Troakes, Claire, Barrett, Matthew J, Beach, Thomas G, Bekris, Lynn M, Bennett, David A, Boeve, Bradley F, Dickson, Dennis W, Faber, Kelley, Ferman, Tanis, Flanagan, Margaret E, Foroud, Tatiana M, Ghetti, Bernardino, and Gibbs, J Raphael

Subjects
Biological Sciences, Genetics, Brain Disorders, Dementia, ALS, Rare Diseases, Neurodegenerative, Neurosciences, Human Genome, Frontotemporal Dementia (FTD), Alzheimer's Disease, Alzheimer's Disease Related Dementias (ADRD), Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Aging, Aetiology, 2.1 Biological and endogenous factors, Neurological, American Genome Center, International LBD Genomics Consortium, International ALS/FTD Consortium, PROSPECT Consortium, Lewy body dementia, amyotrophic lateral sclerosis, case-control study, frontotemporal dementia, genome-wide association study, non–Alzheimer's dementia, resource, structural variant
Abstract

We characterized the role of structural variants, a largely unexplored type of genetic variation, in two non-Alzheimer's dementias, namely Lewy body dementia (LBD) and frontotemporal dementia (FTD)/amyotrophic lateral sclerosis (ALS). To do this, we applied an advanced structural variant calling pipeline (GATK-SV) to short-read whole-genome sequence data from 5,213 European-ancestry cases and 4,132 controls. We discovered, replicated, and validated a deletion in TPCN1 as a novel risk locus for LBD and detected the known structural variants at the C9orf72 and MAPT loci as associated with FTD/ALS. We also identified rare pathogenic structural variants in both LBD and FTD/ALS. Finally, we assembled a catalog of structural variants that can be mined for new insights into the pathogenesis of these understudied forms of dementia.

Published
2023

141. Pre Pre-Service Teacher Training: Professional Preparation and Work-Integrated Learning Pedagogy

Author

Martin, Andrew J., Slade, Dennis G., and Hodges, Lynette D.

Abstract

In order to compensate for a demise in New Zealand's pre-service teacher training, particularly in health and physical education (HPE), a work-integrated learning (WIL) course was added to a Bachelor of Sport and Exercise curriculum. This exploratory research provides insights into the outcomes of twenty-nine final year undergraduate PE students' involvement in teaching, coaching and management of school sports events and activities. The impact of initiatives resulted in enhanced participation, opportunities and engagement in physical education and sport activity for a range of children. Themes emerged from content analysis of student perceptions of individual's learning outcomes. WIL opportunities enabled students to build self-efficacy and career capability despite the COVID-19 restrictions and lockdowns. Findings indicated that from the students' perspectives, school-based initiatives enriched career capability, whilst also requiring adaptability, flexibility and resilience. The WIL experience enabled development of transferable skills and attributes in preparation for pre-service teacher training.

Published
2022

142. Virtual Monitoring and Evaluation of Capacity Development in Higher Education Projects: Lessons for the Future

Author

George, Varkey, Jacobs, Lynette, and Hodges, Merle

Abstract

Generally, project monitoring and evaluation (M&E) are mandatory actions throughout the project planning, implementation and conclusion phases. Although the terms "monitoring" and "evaluation" go together, evaluation is usually conducted after the project is completed and is typically included as part of the project report, while monitoring is a continuous process of ongoing data collection and feedback. This aspect is often neglected. Although M&E guidelines for practitioners are in abundance, and advocacy for the use of specific models of M&E are aplenty, there is a deficit of scholarly publications on M&E of capacity development projects in higher education in particular. Furthermore, research guiding future M&E endeavours based on lessons learnt before and during the pandemic, is found wanting. The three authors, in different roles, are part of an Erasmus+ co-funded project that aims to build capacity for curriculum transformation through internationalisation and development of Collaborative Online International Learning (COIL). COIL is an inclusive approach to provide all students with virtual internationalised learning experiences without having to travel. Taking an insiders' perspective and sharing our experiences in this project, this paper should inform future M&E of capacity building projects. [For the complete Volume 20 proceedings, see ED622631.]

Published
2022

143. Historical Review of How-to-Study Courses and the Emergence of First-Year Seminars and Learning Frameworks Courses

Author

Russ Hodges, Jonathan Lollar, and Taylor Acee

Abstract

Since the 1920s, colleges have offered how-to-study courses orientating students to the rituals of academic study. We present an historical overview of these courses by highlighting major developments including the emergence of courses that evolved from skill-based curriculum underpinned by behaviorism to strategy-based curriculum underpinned by cognitive psychology and self-regulation theories. We also focus on two unique common iterations of course categories offered today: first-year seminars, which were re-envisioned by the University of South Carolina in the 1970s, and theory-based learning strategy courses, often referred to as learning frameworks courses, which emerged in the 1970s at two Texas universities.

Published
2022

144. Deep Synoptic Array science: Two fast radio burst sources in massive galaxy clusters

Author

Connor, Liam, Ravi, Vikram, Catha, Morgan, Chen, Ge, Faber, Jakob T., Lamb, James W., Hallinan, Gregg, Harnach, Charlie, Hellbourg, Greg, Hobbs, Rick, Hodge, David, Hodges, Mark, Law, Casey, Rasmussen, Paul, Sayers, Jack, Sharma, Kritti, Sherman, Myles B., Shi, Jun, Simard, Dana, Somalwar, Jean, Squillace, Reynier, Weinreb, Sander, Woody, David P., and Yadlapalli, Nitika

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The hot gas that constitutes the intracluster medium (ICM) has been studied at X-ray and millimeter/sub-millimeter wavelengths (Sunyaev-Zeldovich effect) for decades. Fast radio bursts (FRBs) offer an additional method of directly measuring the ICM and gas surrounding clusters, via observables such as dispersion measure (DM) and Faraday rotation measure (RM). We report the discovery of two FRB sources detected with the Deep Synoptic Array (DSA-110) whose host galaxies belong to massive galaxy clusters. In both cases, the FRBs exhibit excess extragalactic DM, some of which likely originates in the ICM of their respective clusters. FRB 20220914A resides in the galaxy cluster Abell 2310 at z=0.1125 with a projected offset from the cluster center of 520 kpc. The host of a second source, FRB 20220509G, is an elliptical galaxy at z=0.0894 that belongs to the galaxy cluster Abell 2311 at projected offset of 870 kpc. These sources represent the first time an FRB has been localized to a galaxy cluster. We combine our FRB data with archival X-ray, SZ, and optical observations of these clusters in order to infer properties of the ICM, including a measurement of gas temperature from DM and ySZ of 0.8-3.9 keV. We then compare our results to massive cluster halos from the IllustrisTNG simulation. Finally, we describe how large samples of localized FRBs from future surveys will constrain the ICM, particularly beyond the virial radius of clusters.

Published
2023
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145. Deep Synoptic Array science: A massive elliptical host among two galaxy-cluster fast radio bursts

Author

Sharma, Kritti, Somalwar, Jean, Law, Casey, Ravi, Vikram, Catha, Morgan, Chen, Ge, Connor, Liam, Faber, Jakob T., Hallinan, Gregg, Harnach, Charlie, Hellbourg, Greg, Hobbs, Rick, Hodge, David, Hodges, Mark, Lamb, James W., Rasmussen, Paul, Sherman, Myles B., Shi, Jun, Simard, Dana, Squillace, Reynier, Weinreb, Sander, Woody, David P., and Yadlapalli, Nitika

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies
Abstract

The stellar population environments associated with fast radio burst (FRB) sources provide important insights for developing their progenitor theories. We expand the diversity of known FRB host environments by reporting two FRBs in massive galaxy clusters discovered by the Deep Synoptic Array (DSA-110) during its commissioning observations. FRB 20220914A has been localized to a star-forming, late-type galaxy at a redshift of 0.1139 with multiple starbursts at lookback times less than $\sim$3.5 Gyr in the Abell 2310 galaxy cluster. Although the host galaxy of FRB 20220914A is similar to typical FRB hosts, the FRB 20220509G host stands out as a quiescent, early-type galaxy at a redshift of 0.0894 in the Abell 2311 galaxy cluster. The discovery of FRBs in both late and early-type galaxies adds to the body of evidence that the FRB sources have multiple formation channels. Therefore, even though FRB hosts are typically star-forming, there must exist formation channels consistent with old stellar population in galaxies. The varied star formation histories of the two FRB hosts we report indicate a wide delay-time distribution of FRB progenitors. Future work in constraining the FRB delay-time distribution, using methods we develop herein, will prove crucial in determining the evolutionary histories of FRB sources., Comment: 18 pages, 9 figures

Published
2023
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146. Causally-interpretable meta-analysis: clearly-defined causal effects and two case studies

Author

Rott, Kollin W., Bronfort, Gert, Chu, Haitao, Huling, Jared D., Leininger, Brent, Murad, Mohammad Hassan, Wang, Zhen, and Hodges, James S.

Subjects
Statistics - Methodology, Statistics - Applications
Abstract

Meta-analysis is commonly used to combine results from multiple clinical trials, but traditional meta-analysis methods do not refer explicitly to a population of individuals to whom the results apply and it is not clear how to use their results to assess a treatment's effect for a population of interest. We describe recently-introduced causally-interpretable meta-analysis methods and apply their treatment effect estimators to two individual-participant data sets. These estimators transport estimated treatment effects from studies in the meta-analysis to a specified target population using individuals' potentially effect-modifying covariates. We consider different regression and weighting methods within this approach and compare the results to traditional aggregated-data meta-analysis methods. In our applications, certain versions of the causally-interpretable methods performed somewhat better than the traditional methods, but the latter generally did well. The causally-interpretable methods offer the most promise when covariates modify treatment effects and our results suggest that traditional methods work well when there is little effect heterogeneity. The causally-interpretable approach gives meta-analysis an appealing theoretical framework by relating an estimator directly to a specific population and lays a solid foundation for future developments., Comment: 31 pages, 2 figures Submitted to Research Synthesis Methods

Published
2023

147. Causally-Interpretable Random-Effects Meta-Analysis

Author

Clark, Justin M., Rott, Kollin W., Hodges, James S., and Huling, Jared D.

Subjects
Statistics - Methodology
Abstract

Recent work has made important contributions in the development of causally-interpretable meta-analysis. These methods transport treatment effects estimated in a collection of randomized trials to a target population of interest. Ideally, estimates targeted toward a specific population are more interpretable and relevant to policy-makers and clinicians. However, between-study heterogeneity not arising from differences in the distribution of treatment effect modifiers can raise difficulties in synthesizing estimates across trials. The existence of such heterogeneity, including variations in treatment modality, also complicates the interpretation of transported estimates as a generic effect in the target population. We propose a conceptual framework and estimation procedures that attempt to account for such heterogeneity, and develop inferential techniques that aim to capture the accompanying excess variability in causal estimates. This framework also seeks to clarify the kind of treatment effects that are amenable to the techniques of generalizability and transportability.

Published
2023

148. Strong decays of $T_{cc}^+$ at NLO in an effective field theory

Author

Dai, Lin, Fleming, Sean, Hodges, Reed, and Mehen, Thomas

Subjects
High Energy Physics - Phenomenology
Abstract

The $T_{cc}^+$ exotic meson, discovered by the LHCb Collaboration in 2021, can be interpreted as a molecular state of $D^{(*)0}$ and $D^{(*)+}$ mesons. We compute next-to-leading-order (NLO) contributions to the strong decay of $T_{cc}^+$ in an effective field theory for $D$ mesons and pions, considering contributions from one-pion exchange and final-state rescattering. Corrections to the total width, as well as the differential distribution in the invariant mass of the final-state $D$ meson pair are computed. The results remain in good agreement with LHCb experimental results when the NLO contributions are added. The leading uncertainties in the calculation come from terms which depend on the scattering length and effective range in $D$ meson scattering., Comment: 26 pages, 7 figures

Published
2023
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149. Deep Synoptic Array science: a 50 Mpc fast radio burst constrains the mass of the Milky Way circumgalactic medium

Author

Ravi, Vikram, Catha, Morgan, Chen, Ge, Connor, Liam, Cordes, James M., Faber, Jakob T., Lamb, James W., Hallinan, Gregg, Harnach, Charlie, Hellbourg, Greg, Hobbs, Rick, Hodge, David, Hodges, Mark, Law, Casey, Rasmussen, Paul, Sharma, Kritti, Sherman, Myles B., Shi, Jun, Simard, Dana, Somalwar, Jean J., Squillace, Reynier, Weinreb, Sander, Woody, David P., and Yadlapalli, Nitika

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - High Energy Astrophysical Phenomena
Abstract

We present the Deep Synoptic Array (DSA-110) discovery and interferometric localization of the so far non-repeating FRB 20220319D. The FRB originates in a young, rapidly star-forming barred spiral galaxy, IRAS 02044$+$7048, at just 50 Mpc. Although the NE2001 and YMW16 models for the Galactic interstellar-medium (ISM) contribution to the DM of FRB 20220319D exceed its total observed DM, we show that uncertainties in these models accommodate an extragalactic origin for the burst. We derive a conservative upper limit on the DM contributed by the circumgalactic medium (CGM) of the Milky Way: the limit is either 28.7 pc cm$^{-3}$ and 47.3 pc cm$^{-3}$, depending on which of two pulsars nearby on the sky to FRB 20220319D is used to estimate the ISM DM. These limits both imply that the total Galactic CGM mass is $<10^{11}M_{\odot}$, and that the baryonic mass of the Milky Way is $\lesssim60\%$ of the cosmological average given the total halo mass. More stringent albeit less conservative constraints are possible when the DMs of pulsars in the distant globular cluster M53 are additionally considered. Although our constraints are sensitive to possible anisotropy in the CGM and to the assumed form of the radial-density profile, they are not subject to uncertainties in the chemical and thermal properties of the CGM. Our results strongly support scenarios commonly predicted by galaxy-formation simulations wherein feedback processes expel baryonic matter from the halos of galaxies like the Milky Way., Comment: 17 pages, 8 figures, 3 tables, submitted to AAS Journals

Published
2023

150. The link between North Atlantic tropical cyclones and ENSO in seasonal forecasts

Author

Doane-Solomon, Robert, Befort, Daniel, Camp, Joanne, Hodges, Kevin, and Weisheimer, Antje

Subjects
Physics - Atmospheric and Oceanic Physics
Abstract

This study assesses the ability of six European seasonal forecast models to simulate the observed teleconnection between ENSO and tropical cyclones (TCs) over the North Atlantic. While the models generally capture the basin-wide observed link, its magnitude is overestimated in all forecast models compared to reanalysis. Furthermore, the ENSO - TC relationship in the Caribbean is poorly simulated. It is shown that incorrect forecasting of wind shear appears to affect the representation of the teleconnection in some models, however it is not a completely sufficient explanation for the overestimation of the link., Comment: 5 figures + supplement

Published
2022

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