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82,943 results on '"Hafiz A."'

119. Medicinal Plants and Isolated Molecules Demonstrating Immunomodulation Activity as Potential Alternative Therapies for Viral Diseases Including COVID-19

Author

Hassan A. Alhazmi, Asim Najmi, Sadique A. Javed, Shahnaz Sultana, Mohammed Al Bratty, Hafiz A. Makeen, Abdulkarim M. Meraya, Waquar Ahsan, Syam Mohan, Manal M. E. Taha, and Asaad Khalid

Subjects
COVID-19, phytoconstituents, immunomodulation, cellular immunity, humoral, viral infections, Immunologic diseases. Allergy, RC581-607
Abstract

Plants have been extensively studied since ancient times and numerous important chemical constituents with tremendous therapeutic potential are identified. Attacks of microorganisms including viruses and bacteria can be counteracted with an efficient immune system and therefore, stimulation of body’s defense mechanism against infections has been proven to be an effective approach. Polysaccharides, terpenoids, flavonoids, alkaloids, glycosides, and lactones are the important phytochemicals, reported to be primarily responsible for immunomodulation activity of the plants. These phytochemicals may act as lead molecules for the development of safe and effective immunomodulators as potential remedies for the prevention and cure of viral diseases. Natural products are known to primarily modulate the immune system in nonspecific ways. A number of plant-based principles have been identified and isolated with potential immunomodulation activity which justify their use in traditional folklore medicine and can form the basis of further specified research. The aim of the current review is to describe and highlight the immunomodulation potential of certain plants along with their bioactive chemical constituents. Relevant literatures of recent years were searched from commonly employed scientific databases on the basis of their ethnopharmacological use. Most of the plants displaying considerable immunomodulation activity are summarized along with their possible mechanisms. These discussions shall hopefully elicit the attention of researchers and encourage further studies on these plant-based immunomodulation products as potential therapy for the management of infectious diseases, including viral ones such as COVID-19.

Published
2021
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120. Malaria during COVID-19 travel restrictions in Makkah, Saudi Arabia

Author

Melebari, Sami, Hafiz, Abdul, Alzabeedi, Kamal H, Alzahrani, Abdullah A, Almalki, Yehya, Jadkarim, Renad J, Qabbani, Fadel, Bakri, Rowaida, Jalal, Naif A, Mashat, Hutaf, Alsaadi, Aisha, Hakim, Ashwaq, Malibari, Feras Hashim, Alkhyami, Ahmed, and Fallatah, Othman

Published
2024

132. Trehalose and melatonin interactions alleviate cadmium-incited oxidative stress via activating defense related genes and improve ornamental pepper growth

Author

Zulfiqar, Faisal, Moosa, Anam, Alshehri, Dikhnah, Younis, Tahira, Sadique, Muhammad Adnan, Alghanem, Suliman Mohammed Suliman, Rehman, Tanzila, Usama, Hafiz Muhammad, Chen, Jianjun, Şimşek, Özhan, ul Zahra, Umat, Alshaharni, Mohammed O., Alzamel, Nurah M., Alsharari, Sultan F., Fayad, Eman, Ahmed, Temoor, Yılmaz, Nihat, Tolga İzgü, Tütüncü, Mehmet, Şimşek, Özlem, Abeed, Amany H. A., Soliman, Tarek M. A., and Mirmazloum, Iman

Published
2024
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149. Seaweed Phenolics as Natural Antioxidants, Aquafeed Additives, Veterinary Treatments and Cross-Linkers for Microencapsulation

Author

Tharuka Gunathilake, Taiwo O. Akanbi, Hafiz A. R. Suleria, Tim D. Nalder, David S. Francis, and Colin J. Barrow

Subjects
aquafeed, phenolics, seaweed, veterinary drug, antioxidant, cross-linker, Biology (General), QH301-705.5
Abstract

Driven by consumer demand and government policies, synthetic additives in aquafeed require substitution with sustainable and natural alternatives. Seaweeds have been shown to be a sustainable marine source of novel bioactive phenolic compounds that can be used in food, animal and aqua feeds, or microencapsulation applications. For example, phlorotannins are a structurally unique polymeric phenolic group exclusively found in brown seaweed that act through multiple antioxidant mechanisms. Seaweed phenolics show high affinities for binding proteins via covalent and non-covalent bonds and can have specific bioactivities due to their structures and associated physicochemical properties. Their ability to act as protein cross-linkers means they can be used to enhance the rheological and mechanical properties of food-grade delivery systems, such as microencapsulation, which is a new area of investigation illustrating the versatility of seaweed phenolics. Here we review how seaweed phenolics can be used in a range of applications, with reference to their bioactivity and structural properties.

Published
2022
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150. Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce—A Comprehensive Review

Author

Min Shi, Jingyu Gu, Hanjing Wu, Abdur Rauf, Talha Bin Emran, Zidan Khan, Saikat Mitra, Abdullah S. M. Aljohani, Fahad A. Alhumaydhi, Yahya S. Al-Awthan, Omar Bahattab, Muthu Thiruvengadam, and Hafiz A. R. Suleria

Subjects
Lactuca sativa L., bioactive phytochemicals, antioxidant, health benefits, nutrients, Therapeutics. Pharmacology, RM1-950
Abstract

Lettuce is one of the most famous leafy vegetables worldwide with lots of applications from food to other specific uses. There are different types in the lettuce group for consumers to choose from. Additionally, lettuce is an excellent source of bioactive compounds such as polyphenols, carotenoids, and chlorophyll with related health benefits. At the same time, nutrient composition and antioxidant compounds are different between lettuce varieties, especially for green and red lettuce types. The benefit of lettuce consumption depends on its composition, particularly antioxidants, which can function as nutrients. The health benefits rely on their biochemical effect when reaching the bloodstream. Some components can be released from the food matrix and altered in the digestive system. Indeed, the bioaccessibility of lettuce is measuring the quantity of these compounds released from the food matrix during digestion, which is important for health-promoting features. Extraction of bioactive compounds is one of the new trends observed in lettuce and is necessarily used for several application fields. Therefore, this review aims to demonstrate the nutritional value of lettuce and its pharmacological properties. Due to their bioaccessibility and bioavailability, the consumer will be able to comprehensively understand choosing a healthier lettuce diet. The common utilization pattern of lettuce extracted nutrients will also be summarized for further direction.

Published
2022
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