Search

Your search keyword '"Gonzalez, Francisco"' showing total 3,426 results
Start Over Author "Gonzalez, Francisco"

Refine your results

more »

more »

more »

more »

more »

more »

more »
3,426 results on '"Gonzalez, Francisco"'

108. Adherence and impact of an oral nutritional supplement enriched in leucine, EVOO, EPA and DHA, and beta-glucans on the coverage of energy and protein requirements in patients with cancer and malnutrition: Alisenoc study

Author

Milla, Samara Palma, Luna, Pedro P. García, Casariego, Alfonso Vidal, González, Francisco Villazón, Folgueras, Tomás Martín, Jáuregui, Olatz Izaola, Rey, Silvia García, Fernández, Alicia Calleja, Plaza, Bricia López, Quintana, Tamara Casañas, and de Luis Román, Daniel A.

Published
2024
Full Text
View/download PDF

110. Gold nanodoughnut as an outstanding nanoheater for photothermal applications

Author

González-Colsa, Javier, Serrera, Guillermo, Saiz, José María, Ortiz, Dolores, González, Francisco, Bresme, Fernando, Moreno, Fernando, and Albella, Pablo

Subjects
Physics - Optics
Abstract

Photoinduced hyperthermia is a cancer therapy technique that induces death to cancerous cells via heat generated by plasmonic nanoparticles. While previous studies have shown that some nanoparticles can be effective at killing cancer cells under certain conditions, there is still a necessity (or the need) to improve its heating efficiency. In this work, we perform a detailed thermoplasmonic study comparing the most effective nanoparticle geometries up to now with a doughnut-shaped nanoparticle, demonstrating that the latter exhibits a superior tunable photothermal response in practical illumination conditions, i.e., unpolarized light. Furthermore, we show that nanoparticle heating in fluidic environments, i.e., nanoparticles undergoing Brownian rotations, strongly depends on the particle orientation with respect to the illumination source. We conclude that the heating performance of nanodoughnuts is outstanding, with a temperature increment 35% higher than the second best nanoheater (nanodisks). Furthermore, nanodoughnuts feature a weak dependence on orientation, being therefore, ideal candidates for photothermal therapy applications. Finally, we present a designing guide, covering a wide range of toroid designs, which can help on its experimental implementation.

Published
2021
Full Text
View/download PDF

111. Decoherence-free quantum register of nuclear spins in diamond

Author

González, Francisco J. and Coto, Raúl

Subjects
Quantum Physics, Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

Solid-state quantum registers are exceptional for storing quantum information at room temperature with long coherence time. Nevertheless, practical applications toward quantum supremacy require even longer coherence time to allow for more complex algorithms. In this work we propose a quantum register that lies in a decoherence-free subspace to be implemented with color centers in diamond. The quantum information is encoded in two logical states composed of two nearby nuclear spins, while an electron spin is used as ancilla for initialization and control. Moreover, by tuning an off-axis magnetic field we enable non-nuclear-spin-preserving transitions that we use for preparing the register through Stimulating Raman Adiabatic Passage. Furthermore, we use this sequence to manipulate the quantum register and an individual nuclear spin.

Published
2021
Full Text
View/download PDF

118. Granulocyte and monocyte adsorptive apheresis (GMA) in patients with inflammatory bowel disease: A useful therapeutic tool not just in ulcerative colitis but also in Crohn's disease

Author

Fernández-Pérez, Francisco José, Fernández-Moreno, Nuria, Soria-López, Estela, Rodriguez-González, Francisco Javier, Fernández-Galeote, Francisco José, Lifante-Oliva, Ana, Ruíz-Hernández, Concepción, Escalante-Quijaite, Elisabeth, and Rivas-Ruiz, Francisco

Published
2024
Full Text
View/download PDF

123. Multidimensional Adaptive Penalised Splines with Application to Neurons' Activity Studies

Author

Rodríguez-Álvarez, María Xosé, Durbán, María, Eilers, Paul H. C., Lee, Dae-Jin, and Gonzalez, Francisco

Subjects
Statistics - Methodology, Statistics - Applications, Statistics - Computation
Abstract

P-spline models have achieved great popularity both in statistical and in applied research. A possible drawback of P-spline is that they assume a smooth transition of the covariate effect across its whole domain. In some practical applications, however, it is desirable and needed to adapt smoothness locally to the data, and adaptive P-splines have been suggested. Yet, the extra flexibility afforded by adaptive P-spline models is obtained at the cost of a high computational burden, especially in a multidimensional setting. Furthermore, to the best of our knowledge, the literature lacks proposals for adaptive P-splines in more than two dimensions. Motivated by the need for analysing data derived from experiments conducted to study neurons' activity in the visual cortex, this work presents a novel locally adaptive anisotropic P-spline model in two (e.g., space) and three (space and time) dimensions. Estimation is based on the recently proposed SOP (Separation of Overlapping Precision matrices) method, which provides the speed we look for. The practical performance of the proposal is evaluated through simulations, and comparisons with alternative methods are reported. In addition to the spatio-temporal analysis of the data that motivated this work, we also discuss an application in two dimensions on the absenteeism of workers.

Published
2020

125. On a bi-dimensional chemo-repulsion model with nonlinear production

Author

Guillén-González, Francisco, Mallea-Zepeda, Exequiel, and Villamizar-Roa, Élder J.

Subjects
Mathematics - Analysis of PDEs, Mathematics - Optimization and Control
Abstract

In this paper, we study the following parabolic chemo-repulsion with nonlinear production model: $$ \left\{ \begin{array}{rcl} \partial_tu-\Delta u&=&\nabla\cdot(u\nabla v),\\ \partial_tv-\Delta v+v&=&u^p+fv\, 1_{\Omega_c}. \end{array} \right. $$ This problem is related to a bilinear control problem, where the state $(u,v)$ is the cell density and the chemical concentration respectively, and the control $f$ acts in a bilinear form in the chemical equation. For $2D$ domains, we first consider the case of quadratic signal production ($p=2$), proving the existence and uniqueness of global strong state solution for each control, and the existence of global optimum solution. Afterwards, we deduce the optimality system for any local optimum via a Lagrange multiplier Theorem, proving regularity of the Lagrange multipliers. Finally, we consider the case of signal production $u^p$ with $1

Published
2020

126. The genetic architecture of behavioral traits in a spider

Author

Kralj‐Fišer, Simona, Schneider, Jutta M, Kuntner, Matjaž, Laskowski, Kate, and Garcia‐Gonzalez, Francisco

Subjects
Biological Sciences, Ecology, Evolutionary Biology, Pediatric Research Initiative, Behavioral and Social Science, Basic Behavioral and Social Science, Genetics, Mental Health, animal model, animal personality, heritability, sexual dimorphism, sexual selection, Evolutionary biology, Ecological applications
Abstract

The existence of consistent individual differences in behavior has been shown in a number of species, and several studies have found observable sex differences in these behaviors, yet their evolutionary implications remain unclear. Understanding the evolutionary dynamics of behavioral traits requires knowledge of their genetic architectures and whether this architecture differs between the sexes. We conducted a quantitative genetic study in a sexually size-dimorphic spider, Larinioides sclopetarius, which exhibits sex differences in adult lifestyles. We observed pedigreed spiders for aggression, activity, exploration, and boldness and used animal models to disentangle genetic and environmental influences on these behaviors. We detected trends toward (i) higher additive genetic variances in aggression, activity, and exploration in males than females, and (ii) difference in variances due to common environment/maternal effects, permanent environment and residual variance in aggression and activity with the first two variances being higher in males for both behaviors. We found no sex differences in the amount of genetic and environmental variance in boldness. The mean heritability estimates of aggression, activity, exploration, and boldness range from 0.039 to 0.222 with no sizeable differences between females and males. We note that the credible intervals of the estimates are large, implying a high degree of uncertainty, which disallow a robust conclusion of sex differences in the quantitative genetic estimates. However, the observed estimates suggest that sex differences in the quantitative genetic architecture of the behaviors cannot be ruled out. Notably, the present study suggests that genetic underpinnings of behaviors may differ between sexes and it thus underscores the importance of taking sex differences into account in quantitative genetic studies.

Published
2021

127. Atom scattering off a vibrating surface: An example of chaotic scattering with three degrees of freedom

Author

Gonzalez, Francisco, Borondo, Florentino, and Jung, Christof

Subjects
Nonlinear Sciences - Chaotic Dynamics, 70Kxx
Abstract

In this article, we study the classical chaotic scattering of a He atom off a harmonically vibrating Cu surface. The three degrees of freedom (3- dof) model is studied by first considering the non-vibrating 2-dof model for different values of the energy. We calculate the set of singularities of the scattering functions and study its connection with the tangle between the stable and unstable manifolds of the fixed point at an infinite distance to the Cu surface in the Poincar\'e map for different values of the initial energy. With these manifolds, it is possible to construct the stable and unstable manifolds for the 3-dof coupled model considering the extra closed degree of freedom and the deformation of a stack of maps of the 2-dof system calculated at different values of the energy. Also, for the 3-dof system, the resulting invariant manifolds have the correct dimension to divide the constant total energy manifold. By this construction, it is possible to understand the chaotic scattering phenomena for the 3-dof system from a geometric point of view. We explain the connection between the set of singularities of the scattering function, the Jacobian determinant of the scattering function, the relevant invariant manifolds in the scattering problem, and the cross-section, as well as their behavior when the coupling due to the surface vibration is switched on. In particular, we present in detail the connection between the changes in the structure of the caustics in the cross-section and the changes in the zero level set of the Jacobian determinant of the scattering function.

Published
2019

132. Impact of an oral nutritional supplement enriched in leucine, EPA, DHA, and β-glucans on the increase of muscle mass in patients with cancer and malnutrition: The alisenoc trial

Author

Vidal Casariego, Alfonso, García Luna, Pedro P., Villazón González, Francisco, Martín Folgueras, Tomás, Palma Milla, Samara, López Gómez, Juan José, González Navarro, Irene, Calleja Fernández, Alicia, Casañas Quintana, Tamara, López Plaza, Bricia, and de Luis Román, Daniel A.

Published
2023
Full Text
View/download PDF

134. Dynamic response antibodies SARS-CoV-2 human saliva studied using two-dimensional correlation (2DCOS) infrared spectral analysis coupled with receiver operation characteristics analysis

Author

Karthikeyan, Sivakumaran, Mata-Miranda, Monica Maribel, Martinez-Cuazitl, Adriana, Delgado-Macuil, Raul Jacobo, Garibay-Gonzalez, Francisco, Sanchez-Monroy, Virginia, Lopez-Reyes, Alberto, Rojas-Lopez, Marlon, Rivera-Alatorre, Daniel Enrique, and Vazquez-Zapien, Gustavo Jesus

Published
2023
Full Text
View/download PDF

139. Value contribution of cenobamate for the treatment of Focal-Onset Seizures (FOS) in patients with drug-resistant epilepsy (DRE) in Spain through reflective Multi-Criteria Decision Analysis (MCDA)

Author

Falip, Mercè, López González, Francisco Javier, Martín-Herranz, Isabel, Merino-Bohórquez, Vicente, Montoya, Javier, Rey Gómez-Serranillos, Isabel, Rodriguez Uranga, Juan Jesús, Ruiz, Elías, Sancho-López, Aranzazu, Trillo Mata, Jose Luis, Antoni Vallès, Joan, Álvarez-Barón, Elena, Sabaniego, Joel, Subías-Labazuy, Silvia, and Gil, Alicia

Published
2023
Full Text
View/download PDF

141. Polarimetric imaging for the detection of synthetic models of SARS-CoV-2: A proof of concept

Author

Gomez-Gonzalez, Emilio, Muñoz, Olga, Gomez-Martin, Juan Carlos, Aceituno-Castro, Jesus, Fernandez-Muñoz, Beatriz, Navas-Garcia, Jose Manuel, Barriga-Rivera, Alejandro, Fernandez-Lizaranzu, Isabel, Munoz-Gonzalez, Francisco Javier, Parrilla-Giraldez, Ruben, Requena-Lancharro, Desiree, Gil-Gamboa, Pedro, Ramos, José Luis, Rosell-Valle, Cristina, Gomez-Gonzalez, Carmen, Martin-Lopez, Maria, Relimpio-Lopez, Maria Isabel, Perales-Esteve, Manuel A., Puppo-Moreno, Antonio, Garcia-Cozar, Francisco Jose, Olvera-Collantes, Lucia, de los Santos-Trigo, Silvia, Gomez, Emilia, Sanchez-Pernaute, Rosario, Padillo-Ruiz, Javier, and Marquez-Rivas, Javier

Published
2023
Full Text
View/download PDF

143. Back in the saddle: student response to remote online equine science classes

Author

Merson, Courtney, Gonzalez, Francisco Javier Navas, Orth, Emma, Adams, Anneli, and McLean, Amy

Subjects
Zoology, Agricultural, Veterinary and Food Sciences, Animal Production, Biological Sciences, equine, remote learning, precollege, equine science, Animal production
Abstract

The COVID-19 pandemic has challenged professors and students of all disciplines to adjust quickly to remote online teaching and education platforms. In this new era of remote teaching, a greater challenge has been presented in the field of equine science; how to effectively share knowledge that is most often demonstrated by providing students access to live, in-person animal examples. Historically, students and teachers believed skill sets, which are vital for future careers in the industry (e.g., veterinarian) must be learned through hands-on experience. However, in-person methods were not available, so students were taught through the Zoom platform. Students enrolled in various levels of equine science classes were invited to complete a short voluntary questionnaire measuring their response and perception to equine courses taught in an entirely online remote setting by the same professor. One group was comprised of undergraduates majoring in the field (n = 44) in upper level equine science courses, Advanced Equine Reproduction Physiology and/or Equine Enterprise. These students, 41 females and 3 males, ranged in age from 20 to 25 yr, were provided a voluntary questionnaire seeking responses related to the perceived effectiveness and individual preferences of in-class lectures and in-person labs vs. remote online teaching practices. A similar questionnaire was offered on a volunteer basis to precollege students (n = 17). These students, female, high-school students from freshman to senior status (14-18 yr of age), were interested in equine science as a major at UC Davis in the future. This questionnaire evaluated their response to a 2-week remote synchronous online equine science course, which included multiple teaching methods, including lectures, mini labs, and full labs. Responses from both populations suggested that equine courses were perceived as effective when offered as online, remote courses. Live (synchronous) classes and labs offered on Zoom increased engagement and interaction, but students also appreciated the opportunity to access recorded materials. Students responded positively to online remote teaching and found courses to be effective for increasing their knowledge about equine science in an engaging manner, despite their continued preference for in-person instruction.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results