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It is the purpose of this paper to present a case in which a patient with no obvious systemic disease and not receiving any antibiotic or corticosteroid therapy developed oesophageal candidiasis. This led to complete obstruction to the passage of solids and fluids, needing direct removal of the obstruction. We should like to emphasize the signs of this condition through X-ray investigations of the oesophagus, which have been already described

RANDALL1 noted that the perfusion of water containing the teleost Tinca tinca with ethyl m-aminobenzoate (MS 222) caused an increase in heart and respiration rates. Although these increases did not correlate significantly, he concluded that there was probably some connexion between the cardiac and the respiratory centres in the central nervous system.