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101. Role of the Laboratory in Ensuring Global Access to ARV Treatment for HIV-Infected Children: Consensus Statement on the Performance of Laboratory Assays for Early Infant Diagnosis

Author

Stevens, W., primary, Sherman, G., additional, Downing, R., additional, Parsons, L. M., additional, Ou, C.-Y., additional, Crowley, S., additional, Gershy-Damet, G. M., additional, Fransen, K., additional, Bulterys, M., additional, Homsy, J., additional, Lu, L., additional, Finkbeiner, T., additional, and Nkengasong, J. N., additional

Published
2008
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109. Prevalence of Genotypic Resistance among Antiretroviral Drug-Naive HIV-1-Infected Patients in Belgium

Author

Van Vaerenbergh, K, primary, Debaisieux, L, additional, De Cabooter, N, additional, Declercq, C, additional, Desmet, K, additional, Fransen, K, additional, Maes, B, additional, Marissens, D, additional, Miller, K, additional, Muyldermans, G, additional, Sprecher, S, additional, Stuyver, L, additional, Vaira, D, additional, Verhofstede, C, additional, Zissis, G, additional, Van Ranst, M, additional, De Clercq, E, additional, Desmyter, J, additional, and Vandamme, A-M, additional

Published
2001
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111. Evaluation of a newly developed HIV antigen test

Author

Fransen, K., primary, Mertens, G., additional, Stynen, D., additional, Goris, A., additional, Nys, P., additional, Nkengasong, J., additional, Heyndrickx, L., additional, Janssens, W., additional, and van der Groen, G., additional

Published
1997
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113. Sequence Note: Genetic Variability of HIV Type 1 in Bénin

Author

HEYNDRIC X, L., primary, JANSSENS, W., additional, ALARY, M., additional, FRANSEN, K., additional, VEREECKEN, K., additional, COPPENS, S., additional, WILLEMS, B., additional, DAVO, N., additional, GUÈDÈMÈ, A., additional, BAGANIZI, E., additional, JOLY, J., additional, and VAN DER GROEN, G., additional

Published
1996
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117. Reduced Capacity of Antibodies from Patients Infected with Human Immunodeficiency Virus Type 1 (HIV-l) Group 0 to Neutralize Primary Isolates of HIV-1 Group M Viruses

Author

Nyambi, P. N., primary, Nkengasong, J., additional, Peeters, M., additional, Simon, F., additional, Eberle, J., additional, Janssens, W., additional, Fransen, K., additional, Willems, B., additional, Vereecken, K., additional, Heyndrickx, L., additional, Piot, P., additional, and van der Groen, G., additional

Published
1995
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118. Standardisation of primers and an algorithm for HIV-1 diagnostic PCR evaluated in patients harbouring strains of diverse geographical origin

Author

Vandamme, A.-M., primary, Fransen, K., additional, Debaisieux, L., additional, Marissens, D., additional, Sprecher, S., additional, Vaira, D., additional, Vandenbroucke, A.T., additional, Verhofstede, C., additional, Van Dooren, S., additional, Goubau, P., additional, Desmyter, J., additional, De Beenhouwer, H., additional, van der Groen, G., additional, Piot, P., additional, Liesnard, C., additional, Serruys-Schoutens, E., additional, Pierard, D., additional, Lauwers, S., additional, Zissis, G., additional, Miller, K., additional, Clerc, J.Cogniaux-Le, additional, Sondag-Thull, D., additional, Burtonboy, G., additional, Delferriere, N., additional, Van Emmelo, J., additional, Reniers, S., additional, and Plum, J., additional

Published
1995
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119. Genetic Variability of HIV Type 1 in Kenya

Author

JANSSENS, W., primary, HEYNDRICKX, L., additional, FRANSEN, K., additional, TEMMERMAN, M., additional, LEONAERS, A., additional, IVENS, T., additional, MOTTE, J., additional, PIOT, P., additional, and VAN DER GROEN, G., additional

Published
1994
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128. Swab2know: An HIV-Testing Strategy Using Oral Fluid Samples and Online Communication of Test Results for Men Who Have Sex With Men in Belgium

Author

Platteau, Tom, Fransen, Katrien, Apers, Ludwig, Kenyon, Chris, Albers, Laura, Vermoesen, Tine, Loos, Jasna, and Florence, Eric

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
Abstract

BackgroundAs HIV remains a public health concern, increased testing among those at risk for HIV acquisition is important. Men who have sex with men (MSM) are the most important group for targeted HIV testing in Europe. Several new strategies have been developed and implemented to increase HIV-testing uptake in this group, among them the Swab2know project. ObjectiveIn this project, we aim to assess the acceptability and feasibility of outreach and online HIV testing using oral fluid samples as well as Web-based delivery of test results. MethodsSample collection happened between December 2012 and April 2014 via outreach and online sampling among MSM. Test results were communicated through a secured website. HIV tests were executed in the laboratory. Each reactive sample needed to be confirmed using state-of-the-art confirmation procedures on a blood sample. Close follow-up of participants who did not pick up their results, and those with reactive results, was included in the protocol. Participants were asked to provide feedback on the methodology using a short survey. ResultsDuring 17 months, 1071 tests were conducted on samples collected from 898 men. Over half of the samples (553/1071, 51.63%) were collected during 23 outreach sessions. During an 8-month period, 430 samples out of 1071 (40.15%) were collected from online sampling. Additionally, 88 samples out of 1071 (8.22%) were collected by two partner organizations during face-to-face consultations with MSM and male sex workers. Results of 983 out of 1071 tests (91.78%) had been collected from the website. The pickup rate was higher among participants who ordered their kit online (421/430, 97.9%) compared to those participating during outreach activities (559/641, 87.2%; P

Published
2015
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130. Evaluation of a newly developed HIV antigen test

Author

Fransen, K., Mertens, G., Sytnen, D., Goris, A., Nys, P., Nkengasong, J., Heyndrickx, L., Janssens, W., and Vandergroen, G.

Subjects
HIV testing -- Innovations, Enzyme-linked immunosorbent assay -- Evaluation, Diagnostic reagents and test kits -- Evaluation
Abstract

Fransen, K.; Mertens, G.; Stynen, D.; Goris, A.; Nys, P.; Nkengasong, J.; Heyndrickx, L.; Janssens, W.; Vandergroen, G. "Evaluation of a Newly Developed HIV Antigen Test." Journal of Medical Virology, [...]

Published
1997

131. Virologic, immunologic, and clinical follow-up of a couple infected by the human immunodeficiency virus type one, group O

Author

Nkengasong, J.N., Fransen, K., Willems, B., Karita, E., Vingerhoets, J., Kestens, L., Colebunders, R., Piot, P., and Vandergroen, G.

Subjects
HIV infection -- Development and progression, HIV patients -- Health aspects
Abstract

According to the authors' abstract of an article published in Journal of Medical Virology, "The pathogenic course (virologic, immunologic, and clinical changes) of infection due to human immunodeficiency virus type [...]

Published
1997

132. Biological phenotypes of HIV-1 subtypes A and B strains of diverse origins

Author

Nkengasong, J.N., Peeters, M., Zhong, P., Willems, B., Janssens, W., Heyndrickx, L., Fransen, K., Ndumbe, P.M., Gershydamet, G.M., Nys, P., Kestens, L., Piot, P., and Vandergroen, G.

Subjects
HIV (Viruses) -- Genetic aspects
Abstract

According to the authors' abstract of an article published in Journal of Medical Virology, "The identification of specific biologic phenotypic traits that can be correlated with different HIV-1 genetic subtypes [...]

Published
1995

133. Genotypic subtypes of HIV-1 in Cameroon

Author

Nkengasong, J.N., Janssens, W., Heyndrickx, L., Fransen, K., Ndumbe, P.M., Motte, J., Leonaers, A., Ngolle, M., Ayuk, J., Piot, P., and Vandergroen, G.

Subjects
HIV (Viruses) -- Genetic aspects
Abstract

Nkengasong, J.N.; Janssens, W.; Heyndrickx, L.; Fransen, K.; Ndumbe, P.M.; Motte, J.; Leonaers, A.; Ngolle, M.; Ayuk, J.; Piot, P.; Vandergroen, G. "Genotypic Subtypes of HIV-1 in Cameroon." AIDS, October [...]

Published
1994

134. HIV-1 subtypes in Cameroon

Author

Nkengasong, J.N., Janssens, W., Heyndrickx, L., Ndumbe, P., Fransen, K., Leonaers, A., Motte, J., Ngolle, M., Ayuk, J., Piot, P., and Groen, G. van der

Subjects
HIV (Viruses) -- Genetic aspects, Cameroon -- Health aspects
Abstract

AUTHORS: J.N. Nkengasong( 1), W. Janssens( 1), L. Heyndrickx( 1), P. Ndumbe( 2), K. Fransen( 1), A. Leonaers( 1), J. Motte( 1), M. Ngolle( 3), J. Ayuk( 3), P. Piot( [...]

Published
1994

136. New horizons for fundamental physics with LISA

Author

K. G. Arun, Enis Belgacem, Robert Benkel, Laura Bernard, Emanuele Berti, Gianfranco Bertone, Marc Besancon, Diego Blas, Christian G. Böhmer, Richard Brito, Gianluca Calcagni, Alejandro Cardenas-Avendaño, Katy Clough, Marco Crisostomi, Valerio De Luca, Daniela Doneva, Stephanie Escoffier, José María Ezquiaga, Pedro G. Ferreira, Pierre Fleury, Stefano Foffa, Gabriele Franciolini, Noemi Frusciante, Juan García-Bellido, Carlos Herdeiro, Thomas Hertog, Tanja Hinderer, Philippe Jetzer, Lucas Lombriser, Elisa Maggio, Michele Maggiore, Michele Mancarella, Andrea Maselli, Sourabh Nampalliwar, David Nichols, Maria Okounkova, Paolo Pani, Vasileios Paschalidis, Alvise Raccanelli, Lisa Randall, Sébastien Renaux-Petel, Antonio Riotto, Milton Ruiz, Alexander Saffer, Mairi Sakellariadou, Ippocratis D. Saltas, B. S. Sathyaprakash, Lijing Shao, Carlos F. Sopuerta, Thomas P. Sotiriou, Nikolaos Stergioulas, Nicola Tamanini, Filippo Vernizzi, Helvi Witek, Kinwah Wu, Kent Yagi, Stoytcho Yazadjiev, Nicolás Yunes, Miguel Zilhão, Niayesh Afshordi, Marie-Christine Angonin, Vishal Baibhav, Enrico Barausse, Tiago Barreiro, Nicola Bartolo, Nicola Bellomo, Ido Ben-Dayan, Eric A. Bergshoeff, Sebastiano Bernuzzi, Daniele Bertacca, Swetha Bhagwat, Béatrice Bonga, Lior M. Burko, Geoffrey Compére, Giulia Cusin, Antonio da Silva, Saurya Das, Claudia de Rham, Kyriakos Destounis, Ema Dimastrogiovanni, Francisco Duque, Richard Easther, Hontas Farmer, Matteo Fasiello, Stanislav Fisenko, Kwinten Fransen, Jörg Frauendiener, Jonathan Gair, László Árpád Gergely, Davide Gerosa, Leonardo Gualtieri, Wen-Biao Han, Aurelien Hees, Thomas Helfer, Jörg Hennig, Alexander C. Jenkins, Eric Kajfasz, Nemanja Kaloper, Vladimír Karas, Bradley J. Kavanagh, Sergei A. Klioner, Savvas M. Koushiappas, Macarena Lagos, Christophe Le Poncin-Lafitte, Francisco S. N. Lobo, Charalampos Markakis, Prado Martín-Moruno, C. J. A. P. Martins, Sabino Matarrese, Daniel R. Mayerson, José P. Mimoso, Johannes Noller, Nelson J. Nunes, Roberto Oliveri, Giorgio Orlando, George Pappas, Igor Pikovski, Luigi Pilo, Jiří Podolský, Geraint Pratten, Tomislav Prokopec, Hong Qi, Saeed Rastgoo, Angelo Ricciardone, Rocco Rollo, Diego Rubiera-Garcia, Olga Sergijenko, Stuart Shapiro, Deirdre Shoemaker, Alessandro Spallicci, Oleksandr Stashko, Leo C. Stein, Gianmassimo Tasinato, Andrew J. Tolley, Elias C. Vagenas, Stefan Vandoren, Daniele Vernieri, Rodrigo Vicente, Toby Wiseman, Valery I. Zhdanov, Miguel Zumalacárregui, UAM. Departamento de Física Teórica, Arun, K, Belgacem, E, Benkel, R, Bernard, L, Berti, E, Bertone, G, Besancon, M, Blas, D, Bohmer, C, Brito, R, Calcagni, G, Cardenas-Avendano, A, Clough, K, Crisostomi, M, De Luca, V, Doneva, D, Escoffier, S, Ezquiaga, J, Ferreira, P, Fleury, P, Foffa, S, Franciolini, G, Frusciante, N, Garcia-Bellido, J, Herdeiro, C, Hertog, T, Hinderer, T, Jetzer, P, Lombriser, L, Maggio, E, Maggiore, M, Mancarella, M, Maselli, A, Nampalliwar, S, Nichols, D, Okounkova, M, Pani, P, Paschalidis, V, Raccanelli, A, Randall, L, Renaux-Petel, S, Riotto, A, Ruiz, M, Saffer, A, Sakellariadou, M, Saltas, I, Sathyaprakash, B, Shao, L, Sopuerta, C, Sotiriou, T, Stergioulas, N, Tamanini, N, Vernizzi, F, Witek, H, Wu, K, Yagi, K, Yazadjiev, S, Yunes, N, Zilhao, M, Afshordi, N, Angonin, M, Baibhav, V, Barausse, E, Barreiro, T, Bartolo, N, Bellomo, N, Ben-Dayan, I, Bergshoeff, E, Bernuzzi, S, Bertacca, D, Bhagwat, S, Bonga, B, Burko, L, Compere, G, Cusin, G, da Silva, A, Das, S, de Rham, C, Destounis, K, Dimastrogiovanni, E, Duque, F, Easther, R, Farmer, H, Fasiello, M, Fisenko, S, Fransen, K, Frauendiener, J, Gair, J, Gergely, L, Gerosa, D, Gualtieri, L, Han, W, Hees, A, Helfer, T, Hennig, J, Jenkins, A, Kajfasz, E, Kaloper, N, Karas, V, Kavanagh, B, Klioner, S, Koushiappas, S, Lagos, M, Poncin-Lafitte, C, Lobo, F, Markakis, C, Martin-Moruno, P, Martins, C, Matarrese, S, Mayerson, D, Mimoso, J, Noller, J, Nunes, N, Oliveri, R, Orlando, G, Pappas, G, Pikovski, I, Pilo, L, Podolsky, J, Pratten, G, Prokopec, T, Qi, H, Rastgoo, S, Ricciardone, A, Rollo, R, Rubiera-Garcia, D, Sergijenko, O, Shapiro, S, Shoemaker, D, Spallicci, A, Stashko, O, Stein, L, Tasinato, G, Tolley, A, Vagenas, E, Vandoren, S, Vernieri, D, Vicente, R, Wiseman, T, Zhdanov, V, Zumalacarregui, M, Laboratoire Univers et Théories (LUTH (UMR_8102)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Département de Physique des Particules (ex SPP) (DPhP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique Théorique [Palaiseau] (CPHT), École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des deux Infinis de Toulouse (L2IT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Théorique - UMR CNRS 3681 (IPHT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Systèmes de Référence Temps Espace (SYRTE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique et chimie de l'environnement (LPCE), Institut national des sciences de l'Univers (INSU - CNRS)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS), LISA, Arun, K. G., Belgacem, Eni, Benkel, Robert, Bernard, Laura, Berti, Emanuele, Bertone, Gianfranco, Besancon, Marc, Blas, Diego, B??hmer, Christian G., Brito, Richard, Calcagni, Gianluca, Cardenas-Avenda??o, Alejandro, Clough, Katy, Crisostomi, Marco, De Luca, Valerio, Doneva, Daniela, Escoffier, Stephanie, Mar??a Ezquiaga, Jos??, Ferreira, Pedro G., Fleury, Pierre, Foffa, Stefano, Franciolini, Gabriele, Frusciante, Noemi, Garc??a-Bellido, Juan, Herdeiro, Carlo, Hertog, Thoma, Hinderer, Tanja, Jetzer, Philippe, Lombriser, Luca, Maggio, Elisa, Maggiore, Michele, Mancarella, Michele, Maselli, Andrea, Nampalliwar, Sourabh, Nichols, David, Okounkova, Maria, Pani, Paolo, Paschalidis, Vasileio, Raccanelli, Alvise, Randall, Lisa, Renaux-Petel, S??bastien, Riotto, Antonio, Ruiz, Milton, Saffer, Alexander, Sakellariadou, Mairi, Saltas, Ippocratis D., Sathyaprakash, B. S., Shao, Lijing, Sopuerta, Carlos F., Sotiriou, Thomas P., Stergioulas, Nikolao, Tamanini, Nicola, Vernizzi, Filippo, Witek, Helvi, Wu, Kinwah, Yagi, Kent, Yazadjiev, Stoytcho, Yunes, Nicol??, Zilh??o, Miguel, Afshordi, Niayesh, Angonin, Marie-Christine, Baibhav, Vishal, Barausse, Enrico, Barreiro, Tiago, Bartolo, Nicola, Bellomo, Nicola, Ben-Dayan, Ido, Bergshoeff, Eric A., Bernuzzi, Sebastiano, Bertacca, Daniele, Bhagwat, Swetha, Bonga, B??atrice, Burko, Lior M., Comp??re, Geoffrey, Cusin, Giulia, da Silva, Antonio, Das, Saurya, de Rham, Claudia, Destounis, Kyriako, Dimastrogiovanni, Ema, Duque, Francisco, Easther, Richard, Farmer, Honta, Fasiello, Matteo, Fisenko, Stanislav, Fransen, Kwinten, Frauendiener, J??rg, Gair, Jonathan, rp??d Gergely, L??szl??, Gerosa, Davide, Gualtieri, Leonardo, Han, Wen-Biao, Hees, Aurelien, Helfer, Thoma, Hennig, J??rg, Jenkins, Alexander C., Kajfasz, Eric, Kaloper, Nemanja, Karas, Vladim??r, Kavanagh, Bradley J., Klioner, Sergei A., Koushiappas, Savvas M., Lagos, Macarena, Le Poncin-Lafitte, Christophe, Lobo, Francisco S. N., Markakis, Charalampo, Mart??n-Moruno, Prado, Martins, C. J. A. P., Matarrese, Sabino, Mayerson, Daniel R., Mimoso, Jos?? P., Noller, Johanne, Nunes, Nelson J., Oliveri, Roberto, Orlando, Giorgio, Pappas, George, Pikovski, Igor, Pilo, Luigi, Podolsk??, Ji????, Pratten, Geraint, Prokopec, Tomislav, Qi, Hong, Rastgoo, Saeed, Ricciardone, Angelo, Rollo, Rocco, Rubiera-Garcia, Diego, Sergijenko, Olga, Shapiro, Stuart, Shoemaker, Deirdre, Spallicci, Alessandro, Stashko, Oleksandr, Stein, Leo C., Tasinato, Gianmassimo, Tolley, Andrew J., Vagenas, Elias C., Vandoren, Stefan, Vernieri, Daniele, Vicente, Rodrigo, Wiseman, Toby, Zhdanov, Valery I., Zumalac??rregui, Miguel, National Science Foundation (US), National Aeronautics and Space Administration (US), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Generalitat de Catalunya, European Research Council, European Commission, Fundação para a Ciência e a Tecnologia (Portugal), Ministero dell'Istruzione, dell'Università e della Ricerca, Fundación 'la Caixa', Czech Science Foundation, Science and Technology Facilities Council (UK), GRAPPA (ITFA, IoP, FNWI), and Astroparticle Physics (IHEF, IoP, FNWI)

Subjects
Astrofísica, PROTOPLANET MIGRATION, Física-Modelos matemáticos, Physics and Astronomy (miscellaneous), gr-qc, FOS: Physical sciences, General Relativity and Quantum Cosmology (gr-qc), GRAVITATIONAL-WAVES, horizon, Fundamental physic, General Relativity and Quantum Cosmology, Physics, Particles & Fields, Gravitational waves, LIGO (Observatory), Tests of general relativity, Settore FIS/05 - Astronomia e Astrofisica, DARK-MATTER, Física matemática, KOZAI MECHANISM, High Energy Physics, GENERAL-RELATIVITY, Fundamental physics, LISA, PRIMORDIAL BLACK-HOLES, Science & Technology, General Relativity and Cosmology, 83CXX, Physics, gravitation: interaction, gravitational radiation, Física, Compact, QUANTUM-GRAVITY, Physical Sciences, Astronomia, [PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc], fundamental physics, gravitational waves, test of general relativity, MODIFIED GRAVITY, Gravitational wave, MULTIPOLE MOMENTS, HUBBLE CONSTANT
Abstract

K. G. Arun et al., The Laser Interferometer Space Antenna (LISA) has the potential to reveal wonders about the fundamental theory of nature at play in the extreme gravity regime, where the gravitational interaction is both strong and dynamical. In this white paper, the Fundamental Physics Working Group of the LISA Consortium summarizes the current topics in fundamental physics where LISA observations of gravitational waves can be expected to provide key input. We provide the briefest of reviews to then delineate avenues for future research directions and to discuss connections between this working group, other working groups and the consortium work package teams. These connections must be developed for LISA to live up to its science potential in these areas., E. Berti is supported by NSF Grants No. PHY-1912550 and AST-2006538, NASA ATP Grants No. 17-ATP17-0225 and 19-ATP19-0051, NSF-XSEDE Grant No. PHY-090003, and NSF Grant PHY-20043. D. Blas is supported by a ‘Ayuda Beatriz Galindo Senior’ from the Spanish ‘Ministerio de Universidades’, grant BG20/00228. IFAE is partially funded by the CERCA program of the Generalitat de Catalunya. The research leading of to these results has received funding from the Spanish Ministry of Science and Innovation (PID2020-115845GB-I00/AEI/10.13039/501100011033). K. Clough is supported by funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 693024). A. Cárdenas-Avendaño acknowledges funding from the Fundación Universitaria Konrad Lorenz (Project 5INV1) and from Will and Kacie Snellings. M. Crisostomi and E. Barausse are supported by the European Union’s H2020 ERC Consolidator Grant “GRavity from Astrophysical to Microscopic Scales” (Grant No. GRAMS-815673). P. Fleury received the support of a fellowship from “la Caixa” Foundation (ID 100010434). The fellowship code is LCF/BQ/PI19/11690018. C. Herdeiro thanks the support of the Center for Research and Development in Mathematics and Applications (CIDMA) through the Portuguese Foundation for Science and Technology (FCT - Fundação para a Ciência e a Tecnologia), references UIDB/04106/2020 and UIDP/04106/2020, the projects PTDC/FIS-OUT/28407/2017, CERN/FIS-PAR/0027/2019, PTDC/FIS-AST/3041/2020 and the European Union’s Horizon 2020 research and innovation (RISE) programme H2020-MSCA-RISE-2017 Grant No. FunFiCO-777740. P. Pani and E. Maggio acknowledge financial support provided under the European Union’s H2020 ERC, Starting Grant agreement no. DarkGRA–757480, and under the MIUR PRIN and FARE programmes (GW-NEXT, CUP: B84I20000100001), and support from the Amaldi Research Center funded by the MIUR program “Dipartimento di Eccellenza” (CUP: B81I18001170001). N.Frusciante was supported by Fundação para a Ciência e a Tecnologia (FCT) through the research grants UIDB/04434/2020, UIDP/04434/2020, PTDC/FIS-OUT/29048/2017, CERN/FIS-PAR/0037/2019, the FCT project “CosmoTests—Cosmological tests of gravity theories beyond General Relativity” with ref. number CEECIND/00017/2018 and the FCT project “BEYLA –BEYond LAmbda” with ref. number PTDC/FIS-AST/0054/2021. L.Lombriser was supported by a Swiss National Science Foundation Professorship grant (No. 170547). S.N. acknowledges support from the Alexander von Humboldt Foundation. D.N. acknowledges support from the NSF Grant No. PHY-2011784. R.B. acknowledges financial support from FCT – Fundação para a Ciência e a Tecnologia, I.P., under the Scientific Employment Stimulus - Individual Call - 2020.00470.CEECIND. V. Paschalidis acknowledges support from NSF Grant PHY-1912619 and NASA Grant 80NSSC20K1542 to the University of Arizona. B.S.S. is supported by NSF grants No. AST-2006384 and PHY-2012083. C.F.S. is supported by contracts ESP2017-90084-P and PID2019-106515GB-I00/AEI/10.13039/501100011033 (Spanish Ministry of Science and Innovation) and 2017-SGR-1469 (AGAUR, Generalitat de Catalunya). T. P. S. acknowledges partial support from the STFC Consolidated Grant No. ST/P000703/1. M. Ruiz acknowledges support from NASA Grant 80NSSC17K0070 to the University of Illinois at Urbana-Champaign. I.D. Saltas is supported by the Czech Science Foundation GAČR, Grant No. 21-16583M. N. Stergioulas is supported by the ESA Prodex grant PEA:4000132310 “LISA Stochastic Signals Analysis Pipeline”. F.V. acknowledges partial support from CNES. K.Y. acknowledges support from NSF Grant PHY-1806776, NASA Grant 80NSSC20K0523, a Sloan Foundation Research Fellowship and the Owens Family Foundation. K.Y. would like to also acknowledge support by the COST Action GWverse CA16104 and JSPS KAKENHI Grants No. JP17H06358. N. Yunes acknowledges support from NASA Grants No. NNX16AB98G, 80NSSC17M0041 and 80NSSC18K1352, NSF Award No. 1759615, and the Simons Foundation through MPS Award Number 896696. D.D. acknowledge financial support via an Emmy Noether Research Group funded by the German Research Foundation (DFG) under grant no. DO 1771/1-1.

Published
2022

137. Social Support

Author

Hartley, Chris, Haslam, S Alexander, Coffee, Pete, Rees, Tim, Haslam, S A, Fransen, K, and Boen, F

Abstract

First paragraph: Flick through any autobiography of a celebrated athlete and you will find that one of its key themes is social support. Certainly there will be discussions of training and tactics, distress and disappointment, guts and glory. But the backdrop to all this is likely to be the support the athlete received from key individuals and groups along the way. The mother who drove them to training every day in the middle of winter, the coach who instilled a sense of self-discipline and pride, the backroom team who always had a kind word when things hadn’t gone quite to plan. This is beautifully exemplified by a legendary yet bitter-sweet moment from the 1992 Barcelona Olympics, where hot-favourite sprinter Derek Redmond from the United Kingdom tore his hamstring during the 400 meters semi-final. His father, Jim, jumped the balustrades and pushed past event officials to help his son cross the line and finish the race. We hobbled over the finishing line with our arms round each other, just me and my dad, the man I’m really close to, who’s supported my athletics career since I was seven years old. (Bos, 2017) Accounts such as this are also often filled with heroic examples of athletes going ‘above and beyond’ to provide support to others in their team — even to the extent of making personal sacrifices for the ‘greater good’. Consider the 2012 Tour de France, when Chris Froome gave up his opportunity to secure personal victory, instead opting to help his teammate Bradley Wiggins secure the coveted maillot jaune. Clearly, the role of socially supportive others, across both sport and life more generally, cannot be understated. For this reason, social support plays a key role in optimal functioning across a range of performance contexts — not only in sport, but also in the workplace, at school, or at home (Fletcher & Sarkar, 2012; Freeman & Rees, 2009; Sarkar & Fletcher, 2014). Indeed, work by the fourth author and his colleagues highlighted how supportive families, coaches, and networks are key to the development of super-elite athletes (Rees et al., 2016).

Published
2020

138. Performance of a quantitative human immunodeficiency virus type 1 p24 antigen assay on various HIV-1 subtypes for the follow-up of human immunodeficiency type 1 seropositive individuals

Author

Katrien Fransen, Guido van der Groen, Jörg Schüpbach, Sergio García Ribas, Pascale Ondoa, University of Zurich, and Fransen, K

Subjects
10028 Institute of Medical Virology, Protein Denaturation, Hot Temperature, Anti-HIV Agents, viruses, HIV Core Protein p24, Enzyme-Linked Immunosorbent Assay, HIV Infections, 610 Medicine & health, Sensitivity and Specificity, Virus, law.invention, Viral Proteins, Antigen, law, Virology, Humans, Sida, biology, Reverse Transcriptase Polymerase Chain Reaction, Genetic Variation, virus diseases, RNA, Viral Load, biology.organism_classification, Lentivirus, Immunology, HIV-1, 2406 Virology, Recombinant DNA, RNA, Viral, 570 Life sciences, Viral disease, Viral load
Abstract

The heat-denatured signal-amplified p24 antigen assay is a low-cost test allowing the determination of plasma levels of HIV-1 p24 antigen in infected patients. This assay may be appropriate for monitoring disease progression in HIV seropositive patients in developing countries. Only a few data on the clinical validation of the test are available for HIV-1 non-subtypes B viruses that represent the vast majority of virus circulating in Africa. The present study was undertaken to evaluate and compare the performance of a heat-denatured signal-amplified p24 assay for the determination of p24 viral load in the plasma of individuals infected with different subtypes of HIV-1 and using the RT-PCR-based RNA viral load test as the gold standard. A total of 120 plasma samples from individuals infected with HIV-1 strains belonging to group M (subtypes A→H) and group O, as well as recombinant strains, were tested in parallel with the heat-denatured signal-amplified p24 assay and the RNA viral load. Plasma p24 levels appeared to be correlated significantly with the plasma RNA viral loads (R=0.751, P

Published
2003

139. Black holes, gravitational waves and fundamental physics: a roadmap

Author

Leor Barack, Vitor Cardoso, Samaya Nissanke, Thomas P Sotiriou, Abbas Askar, Chris Belczynski, Gianfranco Bertone, Edi Bon, Diego Blas, Richard Brito, Tomasz Bulik, Clare Burrage, Christian T Byrnes, Chiara Caprini, Masha Chernyakova, Piotr Chruściel, Monica Colpi, Valeria Ferrari, Daniele Gaggero, Jonathan Gair, Juan García-Bellido, S F Hassan, Lavinia Heisenberg, Martin Hendry, Ik Siong Heng, Carlos Herdeiro, Tanja Hinderer, Assaf Horesh, Bradley J Kavanagh, Bence Kocsis, Michael Kramer, Alexandre Le Tiec, Chiara Mingarelli, Germano Nardini, Gijs Nelemans, Carlos Palenzuela, Paolo Pani, Albino Perego, Edward K Porter, Elena M Rossi, Patricia Schmidt, Alberto Sesana, Ulrich Sperhake, Antonio Stamerra, Leo C Stein, Nicola Tamanini, Thomas M Tauris, L Arturo Urena-López, Frederic Vincent, Marta Volonteri, Barry Wardell, Norbert Wex, Kent Yagi, Tiziano Abdelsalhin, Miguel Ángel Aloy, Pau Amaro-Seoane, Lorenzo Annulli, Manuel Arca-Sedda, Ibrahima Bah, Enrico Barausse, Elvis Barakovic, Robert Benkel, Charles L Bennett, Laura Bernard, Sebastiano Bernuzzi, Christopher P L Berry, Emanuele Berti, Miguel Bezares, Jose Juan Blanco-Pillado, Jose Luis Blázquez-Salcedo, Matteo Bonetti, Mateja Bošković, Zeljka Bosnjak, Katja Bricman, Bernd Brügmann, Pedro R Capelo, Sante Carloni, Pablo Cerdá-Durán, Christos Charmousis, Sylvain Chaty, Aurora Clerici, Andrew Coates, Marta Colleoni, Lucas G Collodel, Geoffrey Compère, William Cook, Isabel Cordero-Carrión, Miguel Correia, Álvaro de la Cruz-Dombriz, Viktor G Czinner, Kyriakos Destounis, Kostas Dialektopoulos, Daniela Doneva, Massimo Dotti, Amelia Drew, Christopher Eckner, James Edholm, Roberto Emparan, Recai Erdem, Miguel Ferreira, Pedro G Ferreira, Andrew Finch, Jose A Font, Nicola Franchini, Kwinten Fransen, Dmitry Gal’tsov, Apratim Ganguly, Davide Gerosa, Kostas Glampedakis, Andreja Gomboc, Ariel Goobar, Leonardo Gualtieri, Eduardo Guendelman, Francesco Haardt, Troels Harmark, Filip Hejda, Thomas Hertog, Seth Hopper, Sascha Husa, Nada Ihanec, Taishi Ikeda, Amruta Jaodand, Philippe Jetzer, Xisco Jimenez-Forteza, Marc Kamionkowski, David E Kaplan, Stelios Kazantzidis, Masashi Kimura, Shiho Kobayashi, Kostas Kokkotas, Julian Krolik, Jutta Kunz, Claus Lämmerzahl, Paul Lasky, José P S Lemos, Jackson Levi Said, Stefano Liberati, Jorge Lopes, Raimon Luna, Yin-Zhe Ma, Elisa Maggio, Alberto Mangiagli, Marina Martinez Montero, Andrea Maselli, Lucio Mayer, Anupam Mazumdar, Christopher Messenger, Brice Ménard, Masato Minamitsuji, Christopher J Moore, David Mota, Sourabh Nampalliwar, Andrea Nerozzi, David Nichols, Emil Nissimov, Martin Obergaulinger, Niels A Obers, Roberto Oliveri, George Pappas, Vedad Pasic, Hiranya Peiris, Tanja Petrushevska, Denis Pollney, Geraint Pratten, Nemanja Rakic, Istvan Racz, Miren Radia, Fethi M Ramazanoğlu, Antoni Ramos-Buades, Guilherme Raposo, Marek Rogatko, Roxana Rosca-Mead, Dorota Rosinska, Stephan Rosswog, Ester Ruiz-Morales, Mairi Sakellariadou, Nicolás Sanchis-Gual, Om Sharan Salafia, Anuradha Samajdar, Alicia Sintes, Majda Smole, Carlos Sopuerta, Rafael Souza-Lima, Marko Stalevski, Nikolaos Stergioulas, Chris Stevens, Tomas Tamfal, Alejandro Torres-Forné, Sergey Tsygankov, Kıvanç İ Ünlütürk, Rosa Valiante, Maarten van de Meent, José Velhinho, Yosef Verbin, Bert Vercnocke, Daniele Vernieri, Rodrigo Vicente, Vincenzo Vitagliano, Amanda Weltman, Bernard Whiting, Andrew Williamson, Helvi Witek, Aneta Wojnar, Kadri Yakut, Haopeng Yan, Stoycho Yazadjiev, Gabrijela Zaharijas, Miguel Zilhão, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut des Hautes Etudes Scientifiques (IHES), IHES, Laboratoire Univers et Théories (LUTH (UMR_8102)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Institut national des sciences de l'Univers (INSU - CNRS), Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Théorique d'Orsay [Orsay] (LPT), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut des Hautes Études Scientifiques (IHES), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Barack, L., Cardoso, V., Nissanke, S., Sotiriou, T. P., Askar, A., Belczynski, C., Bertone, G., Bon, E., Blas, D., Brito, R., Bulik, T., Burrage, C., Byrnes, C. T., Caprini, C., Chernyakova, M., Chrusciel, P., Colpi, M., Ferrari, V., Gaggero, D., Gair, J., Garcia-Bellido, J., Hassan, S. F., Heisenberg, L., Hendry, M., Heng, I. S., Herdeiro, C., Hinderer, T., Horesh, A., Kavanagh, B. J., Kocsis, B., Kramer, M., Le Tiec, A., Mingarelli, C., Nardini, G., Nelemans, G., Palenzuela, C., Pani, P., Perego, A., Porter, E. K., Rossi, E. M., Schmidt, P., Sesana, A., Sperhake, U., Stamerra, A., Stein, L. C., Tamanini, N., Tauris, T. M., Urena-Lopez, L. A., Vincent, F., Volonteri, M., Wardell, B., Wex, N., Yagi, K., Abdelsalhin, T., Aloy, M. A., Amaro-Seoane, P., Annulli, L., Arca-Sedda, M., Bah, I., Barausse, E., Barakovic, E., Benkel, R., Bennett, C. L., Bernard, L., Bernuzzi, S., Berry, C. P. L., Berti, E., Bezares, M., Blanco-Pillado, J. J., Blazquez-Salcedo, J. L., Bonetti, M., Boskovic, M., Bosnjak, Z., Bricman, K., Brugmann, B., Capelo, P. R., Carloni, S., Cerda-Duran, P., Charmousis, C., Chaty, S., Clerici, A., Coates, A., Colleoni, M., Collodel, L. G., Compere, G., Cook, W., Cordero-Carrion, I., Correia, M., De La Cruz-Dombriz, A., Czinner, V. G., Destounis, K., Dialektopoulos, K., Doneva, D., Dotti, M., Drew, A., Eckner, C., Edholm, J., Emparan, R., Erdem, R., Ferreira, M., Ferreira, P. G., Finch, A., Font, J. A., Franchini, N., Fransen, K., Gal'Tsov, D., Ganguly, A., Gerosa, D., Glampedakis, K., Gomboc, A., Goobar, A., Gualtieri, L., Guendelman, E., Haardt, F., Harmark, T., Hejda, F., Hertog, T., Hopper, S., Husa, S., Ihanec, N., Ikeda, T., Jaodand, A., Jetzer, P., Jimenez-Forteza, X., Kamionkowski, M., Kaplan, D. E., Kazantzidis, S., Kimura, M., Kobayashi, S., Kokkotas, K., Krolik, J., Kunz, J., Lammerzahl, C., Lasky, P., Lemos, J. P. S., Levi Said, J., Liberati, S., Lopes, J., Luna, R., Ma, Y. -Z., Maggio, E., Mangiagli, A., Montero, M. M., Maselli, A., Mayer, L., Mazumdar, A., Messenger, C., Menard, B., Minamitsuji, M., Moore, C. J., Mota, D., Nampalliwar, S., Nerozzi, A., Nichols, D., Nissimov, E., Obergaulinger, M., Obers, N. A., Oliveri, R., Pappas, G., Pasic, V., Peiris, H., Petrushevska, T., Pollney, D., Pratten, G., Rakic, N., Racz, I., Radia, M., Ramazanoglu, F. M., Ramos-Buades, A., Raposo, G., Rogatko, M., Rosca-Mead, R., Rosinska, D., Rosswog, S., Ruiz-Morales, E., Sakellariadou, M., Sanchis-Gual, N., Sharan Salafia, O., Samajdar, A., Sintes, A., Smole, M., Sopuerta, C., Souza-Lima, R., Stalevski, M., Stergioulas, N., Stevens, C., Tamfal, T., Torres-Forne, A., Tsygankov, S., I Unluturk, Ki., Valiante, R., Van De Meent, M., Velhinho, J., Verbin, Y., Vercnocke, B., Vernieri, D., Vicente, R., Vitagliano, V., Weltman, A., Whiting, B., Williamson, A., Witek, H., Wojnar, A., Yakut, K., Yan, H., Yazadjiev, S., Zaharijas, G., Zilhao, M., Gravitation and Astroparticle Physics Amsterdam, GRAPPA (ITFA, IoP, FNWI), IoP (FNWI), High Energy Astrophys. & Astropart. Phys (API, FNWI), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7), Sperhake, Ulrich [0000-0002-3134-7088], Drew, Amelia [0000-0001-8252-602X], Radia, Miren [0000-0001-8861-2025], Apollo - University of Cambridge Repository, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Ege Üniversitesi, Barack, L, Cardoso, V, Nissanke, S, Sotiriou, T, Askar, A, Belczynski, C, Bertone, G, Bon, E, Blas, D, Brito, R, Bulik, T, Burrage, C, Byrnes, C, Caprini, C, Chernyakova, M, Chruściel, P, Colpi, M, Ferrari, V, Gaggero, D, Gair, J, García-Bellido, J, Hassan, S, Heisenberg, L, Hendry, M, Heng, I, Herdeiro, C, Hinderer, T, Horesh, A, Kavanagh, B, Kocsis, B, Kramer, M, Le Tiec, A, Mingarelli, C, Nardini, G, Nelemans, G, Palenzuela, C, Pani, P, Perego, A, Porter, E, Rossi, E, Schmidt, P, Sesana, A, Sperhake, U, Stamerra, A, Stein, L, Tamanini, N, Tauris, T, Urena-López, L, Vincent, F, Volonteri, M, Wardell, B, Wex, N, Yagi, K, Abdelsalhin, T, Aloy, M, Amaro-Seoane, P, Annulli, L, Arca-Sedda, M, Bah, I, Barausse, E, Barakovic, E, Benkel, R, Bennett, C, Bernard, L, Bernuzzi, S, Berry, C, Berti, E, Bezares, M, Blanco-Pillado, J, Blázquez-Salcedo, J, Bonetti, M, Bošković, M, Bosnjak, Z, Bricman, K, Brügmann, B, Capelo, P, Carloni, S, Cerdá-Durán, P, Charmousis, C, Chaty, S, Clerici, A, Coates, A, Colleoni, M, Collodel, L, Compère, G, Cook, W, Cordero-Carrión, I, Correia, M, de la Cruz-Dombriz, Á, Czinner, V, Destounis, K, Dialektopoulos, K, Doneva, D, Dotti, M, Drew, A, Eckner, C, Edholm, J, Emparan, R, Erdem, R, Ferreira, M, Ferreira, P, Finch, A, Font, J, Franchini, N, Fransen, K, Gal’Tsov, D, Ganguly, A, Gerosa, D, Glampedakis, K, Gomboc, A, Goobar, A, Gualtieri, L, Guendelman, E, Haardt, F, Harmark, T, Hejda, F, Hertog, T, Hopper, S, Husa, S, Ihanec, N, Ikeda, T, Jaodand, A, Jetzer, P, Jimenez-Forteza, X, Kamionkowski, M, Kaplan, D, Kazantzidis, S, Kimura, M, Kobayashi, S, Kokkotas, K, Krolik, J, Kunz, J, Lämmerzahl, C, Lasky, P, Lemos, J, Levi Said, J, Liberati, S, Lopes, J, Luna, R, Ma, Y, Maggio, E, Mangiagli, A, Montero, M, Maselli, A, Mayer, L, Mazumdar, A, Messenger, C, Ménard, B, Minamitsuji, M, Moore, C, Mota, D, Nampalliwar, S, Nerozzi, A, Nichols, D, Nissimov, E, Obergaulinger, M, Obers, N, Oliveri, R, Pappas, G, Pasic, V, Peiris, H, Petrushevska, T, Pollney, D, Pratten, G, Rakic, N, Racz, I, Radia, M, Ramazanoğlu, F, Ramos-Buades, A, Raposo, G, Rogatko, M, Rosca-Mead, R, Rosinska, D, Rosswog, S, Ruiz-Morales, E, Sakellariadou, M, Sanchis-Gual, N, Sharan Salafia, O, Samajdar, A, Sintes, A, Smole, M, Sopuerta, C, Souza-Lima, R, Stalevski, M, Stergioulas, N, Stevens, C, Tamfal, T, Torres-Forné, A, Tsygankov, S, İ Ünlütürk, K, Valiante, R, van de Meent, M, Velhinho, J, Verbin, Y, Vercnocke, B, Vernieri, D, Vicente, R, Vitagliano, V, Weltman, A, Whiting, B, Williamson, A, Witek, H, Wojnar, A, Yakut, K, Yan, H, Yazadjiev, S, Zaharijas, G, and Zilhão, M

Subjects
High Energy Physics - Theory, cosmological model, Physics and Astronomy (miscellaneous), Event horizon, Astronomy, 01 natural sciences, General Relativity and Quantum Cosmology, Cosmology, Physics, Particles & Fields, Gravitation, High Energy Physics::Theory, black hole: formation, Vacuum energy, black hole, general relativity, NEUTRON-STAR, GENERAL-RELATIVITY, dark energy, STAR CLUSTER SIMULATIONS, gravitational wave, QC, QB, media_common, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, astro-ph.HE, Quantum Science & Technology, [PHYS.HTHE]Physics [physics]/High Energy Physics - Theory [hep-th], hep-th, source modelling, BRANS-DICKE THEORY, fundamental physic, gravitational waves, QUASI-NORMAL MODES, Physical Sciences, birth and evolution of black holes, black holes, fundamental physics, gravitational-wave astronomy, [PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc], HIGH-REDSHIFT FORMATION, Astrophysics - High Energy Astrophysical Phenomena, SCALAR-TENSOR THEORIES, General relativity, media_common.quotation_subject, gr-qc, Physics, Multidisciplinary, birth and evolution of black hole, FOS: Physical sciences, ST/R00045X/1, General Relativity and Quantum Cosmology (gr-qc), Astronomy & Astrophysics, gravitational radiation: direct detection, horizon, vacuum state: energy, Theoretical physics, Settore FIS/05 - Astronomia e Astrofisica, 0103 physical sciences, inflation, 010306 general physics, STFC, Science & Technology, 010308 nuclear & particles physics, Gravitational wave, Physique, gravitational radiation, RCUK, ST/P000703/1, R-PROCESS NUCLEOSYNTHESIS, Astronomie, singularity, Universe, High Energy Physics - Theory (hep-th), gravitation, black hole: model, TIMING ARRAY LIMITS, Dark energy, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], X-RAY BINARIES
Abstract

The grand challenges of contemporary fundamental physics-dark matter, dark energy, vacuum energy, inflation and early universe cosmology, singularities and the hierarchy problem-all involve gravity as a key component. And of all gravitational phenomena, black holes stand out in their elegant simplicity, while harbouring some of the most remarkable predictions of General Relativity: event horizons, singularities and ergoregions. The hitherto invisible landscape of the gravitational Universe is being unveiled before our eyes: the historical direct detection of gravitational waves by the LIGO-Virgo collaboration marks the dawn of a new era of scientific exploration. Gravitational-wave astronomy will allow us to test models of black hole formation, growth and evolution, as well as models of gravitational-wave generation and propagation. It will provide evidence for event horizons and ergoregions, test the theory of General Relativity itself, and may reveal the existence of new fundamental fields. The synthesis of these results has the potential to radically reshape our understanding of the cosmos and of the laws of Nature. The purpose of this work is to present a concise, yet comprehensive overview of the state of the art in the relevant fields of research, summarize important open problems, and lay out a roadmap for future progress. This write-up is an initiative taken within the framework of the European Action on 'Black holes, Gravitational waves and Fundamental Physics'., SCOPUS: re.j, info:eu-repo/semantics/published

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140. Measuring leadership in sport: Development and validation of the Identity Leadership Inventory - Youth (ILI-Y).

Author

Butalia R, Miller A, Steffens NK, Haslam SA, Bruner MW, McLaren CD, Boen F, Slater MJ, Dunn K, and Fransen K

Subjects
Humans, Adolescent, Male, Female, Reproducibility of Results, Young Adult, Athletes psychology, Surveys and Questionnaires, Child, United Kingdom, Adult, Leadership, Social Identification, Youth Sports psychology, Psychometrics methods
Abstract

The social identity approach to leadership posits that leaders' effectiveness depends on their ability to represent, advance, create, and embed a shared sense of social identity among their followers. Although significant progress has been made in investigating the benefits of identity leadership in adult sports, research in youth sports is still in its infancy. One reason is the lack of a youth-centric inventory that adequately measures identity leadership in this population. To bridge this gap, we developed and validated a long (16 items) and short (5 items) version of the Identity Leadership Inventory for Youth Sport (ILI-Y or ILI-Y-Short-Form) through five studies conducted in three phases of research. Data were primarily collected in football in the United Kingdom, involving a total of 1096 participants. Results of Phase I of this study provided little to no evidence that the ILI - originally developed for adults - was understandable (Study 1) and had factor validity and internal consistency (Study 2) in a sample of youth athletes. Therefore, in Phase II, the ILI was revised, leading to the development of the ILI-Y, which was understandable for youth athletes (Study 3). Results from Phase II (Study 4) also indicated that the ILI-Y exhibited a unidimensional factor structure, which was subsequently confirmed in Phase III (Study 5). This last phase offered additional evidence for the discriminant, criterion, and incremental validity of the ILI-Y and its short form, along with their measurement invariance across genders and age groups, and internal consistency. This study provides sports psychology researchers and practitioners with a valid measure to assess identity leadership in youth sports., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Published
2024
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141. "I'm more than my sport": Exploring the dynamic processes of identity change in athletic retirement.

Author

Haslam C, McAulay C, Cooper D, Mertens N, Coffee P, Hartley C, Young T, La Rue CJ, Haslam SA, Steffens NK, Cruwys T, Bentley SV, Mallett CJ, McGregor M, Williams D, and Fransen K

Subjects
Humans, Male, Female, Middle Aged, Self Concept, Adult, Athletic Performance psychology, Aged, Sports psychology, Retirement psychology, Social Identification, Athletes psychology, Qualitative Research
Abstract

Retirement is one of the most impactful career transitions athletes face. Researchers recognise the role that athletic identity plays in this, but analysis of identity content and change processes is limited. Addressing this gap, we conducted a qualitative study exploring the experience of identity change in 21 competitive and successful elite athletes who had retired from sport. All participated in a one-session psychoeducational program that explored the challenges of transitioning out of sport before being interviewed about their understanding of identity in sport, and their experiences negotiating identity loss and change in retirement. Using reflexive thematic analysis, we identified three themes: (i) the role of identity and self-categorizations in shaping sport performance, (ii) adjusting to identity loss (with subthemes indicating that this experience varied depending on the extent to which a person had multiple or exclusive identities), and (iii) attempts to remoor identity in the transition (with subthemes of searching for a new identity and actively repurposing identity). We interpret these themes through the lens of the Social Identity Model of Identity Change and show that this provides a framework for extending our understanding the complexities of identity change associated with retirement from elite sport., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper, (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Published
2024
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142. More than sport: A social-identity intervention to support transitions out of elite sport.

Author

Young T, Haslam C, Coffee P, Cooper D, McAulay C, Hartley C, Mertens N, Luong M, La Rue C, Haslam SA, Steffens NK, Cruwys T, Bentley S, Mallett CJ, McGregor M, Williams D, and Fransen K

Subjects
Humans, Male, Female, Adult, Young Adult, Australia, United Kingdom, Belgium, Adolescent, Sports psychology, Social Support, Social Identification, Athletes psychology, Qualitative Research
Abstract

Elite athletes often make large personal sacrifices to pursue excellence, but there is insufficient support for them when they leave elite sport. Identity loss is central to athletes' transition trajectories and hence the management of identity change is a crucial area for support. The More Than Sport (MTS) program is a novel digital intervention that aims to provide this support-helping athletes manage identity change in the process of leaving elite sport. The present research aims to study elite athletes' experiences with the MTS program and their perceptions of its usefulness in managing the transition away from elite sport. We undertook a qualitative study with athletes (N = 25) from three countries (the United Kingdom, Australia and Belgium) using reflexive thematic analysis to explore their experiences of the program and their feedback on program content. We identified three key themes and eight subthemes. The first key theme was Value of the Program, and this was underpinned by four sub-themes that centred on Program importance and novelty, how Positive and confronting experiences afford insight, the Value of developing shared understanding, and Realising the value of social groups. The second key theme was Engagement with Program Elements and here participants commented on Program content and Delivery format. The final key theme was Time and Place for Identity Management Programs which included the sub-themes of Optimal timing and Additional program beneficiaries. Overall, the results highlight the value of MTS specifically, and identity management efforts more broadly, to help elite athletes adjust successfully to life beyond sport., Competing Interests: Declaration of competing interest Authors CH, TC, AC, KF, PC and CH are the developers of More than Sport and thus have an academic interest in the program., (Copyright © 2024. Published by Elsevier Ltd.)

Published
2024
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143. HIV Diagnostics and Vaccines: It Takes Two to Tango.

Author

Colón W, Oriol-Mathieu V, Hural J, Hattingh L, Adungo F, Lagatie O, Lavreys L, Allen M, Anzala O, Espy N, Fransen K, Garcia PJ, Maciel M Jr, Murtagh M, Peel SA, Peeling RW, Tan LLJ, Warren M, Pau MG, and D'Souza PM

Subjects
Humans, HIV Antibodies blood, HIV Antibodies immunology, Serologic Tests methods, HIV Infections diagnosis, HIV Infections prevention & control, AIDS Vaccines immunology, HIV-1 immunology
Abstract

Current serologic tests for HIV screening and confirmation of infection present challenges to the adoption of HIV vaccines. The detection of vaccine-induced HIV-1 antibodies in the absence of HIV-1 infection, referred to as vaccine-induced seropositivity/seroreactivity, confounds the interpretation of test results, causing misclassification of HIV-1 status with potential affiliated stigmatization. For HIV vaccines to be widely adopted with high community confidence and uptake, tests are needed that are agnostic to the vaccination status of tested individuals (ie, positive only for true HIV-1 infection). Successful development and deployment of such tests will require HIV vaccine developers to work in concert with diagnostic developers. Such tests will need to match today's high-performance standards (accuracy, cost-effectiveness, simplicity) for use in vaccinated and unvaccinated populations, especially in low- and middle-income countries with high HIV burden. Herein, we discuss the challenges and strategies for developing modified serologic HIV tests for concurrent deployment with HIV vaccines., Competing Interests: Potential conflicts of interest. W. C. and O. L. are former and current employees of Janssen Pharmaceutica N.V., respectively, and V. O. M. and M. G. P. are current employees of Janssen Vaccines and Prevention B.V. Both are Johnson & Johnson companies, and the authors may own stock or stock options in them. L. L. is a consultant for Janssen Pharmaceutica N.V. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed., (© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Published
2024
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144. The Power of Peer Leaders: Exploring the Link between Peer Leadership Behaviors and Sustainable Work Outcomes.

Author

Edelmann CM, Boen F, Stouten J, Vande Broek G, and Fransen K

Abstract

Most leadership studies primarily focus on formal leaders, often overlooking the influence of leaders within the team. While prior research has shown that peer leaders can have a beneficial impact on various team outcomes, it is yet unclear which peer leadership behaviors precisely foster a supportive and sustainable work environment. Building upon the recent identification of 10 peer leadership roles and 37 underlying functions, the current study aims to investigate the relationships between these peer leadership roles and functions and key outcomes (i.e., job satisfaction, team cohesion, team effectiveness, and OCB). A total of 31 organizational teams, comprising 182 employees from diverse sectors, participated in a quantitative survey. Employing multilevel modeling analysis, the findings demonstrated that each leadership role and nearly every function predicted at least one outcome, highlighting their significance within organizational teams. Additionally, Necessary Condition Analysis revealed that specific roles and functions were necessary for generating one or more outcomes. Finally, we found that most of the significant relationships remained consistent across teams, regardless of their size, tenure, or level of team identification. These findings refine our understanding of shared leadership and how peer leaders can create a sustainable workplace by fostering employee well-being and productivity in organizational teams.

Published
2023
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145. Unlocking the power of 'us': Longitudinal evidence that identity leadership predicts team functioning and athlete well-being.

Author

Fransen K, Boen F, Haslam SA, McLaren CD, Mertens N, Steffens NK, and Bruner MW

Subjects
Humans, Motivation, Athletes, Social Identification, Leadership, Athletic Performance
Abstract

The social identity approach has become an important framework for understanding effective leadership. The present study is the first to longitudinally examine the relative impact of coaches' and athlete leaders' identity leadership on athletes' identification with their team, as well as the subsequent relationships with key team and individual outcomes. To investigate these research questions, 18 sport teams (N = 279) completed a questionnaire early and late in their season competition. To analyse these data, we conducted structural equation modelling and controlled both for baseline values and the nested structure of our data. Results revealed that it was mainly the identity leadership of athlete leaders (and not of the coach) early in the season that predicted athletes' team identification later in the season. This increased team identification in turn fed into both team outcomes (i.e., task climate, team resilience, team performance) and individual outcomes (i.e., well-being, burnout, and individual performance). The mediating role of team identification suggests that by building a shared sense of 'we', athlete leaders can improve the team's effectiveness and enhance athletes' well-being. Accordingly, we conclude that empowering athlete leaders and strengthening their identity leadership skills is an important way to unlock sport teams' full potential.

Published
2022
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146. Refining the definition of the avian pathogenic Escherichia coli (APEC) pathotype through inclusion of high-risk clonal groups.

Author

Johnson TJ, Miller EA, Flores-Figueroa C, Munoz-Aguayo J, Cardona C, Fransen K, Lighty M, Gonder E, Nezworski J, Haag A, Behl M, Kromm M, Wileman B, Studniski M, and Singer RS

Subjects
Animals, Chickens, Escherichia coli, Phylogeny, Poultry, Turkeys, Virulence, Escherichia coli Infections veterinary, Escherichia coli Proteins genetics, Poultry Diseases
Abstract

Colibacillosis in poultry is a unique disease manifestation of Escherichia coli in the animal world, as one of the primary routes of entry is via the respiratory tract of birds. Because of this, a novel extraintestinal pathogenic E. coli (ExPEC) subpathotype coined avian pathogenic E. coli (or APEC) has been described. Like other ExPEC, this pathotype has been challenging to clearly define, and in the case of APEC, its role as an opportunistic pathogen has further complicated these challenges. Using 3,479 temporally matched genomes of poultry-source isolates, we show that the APEC plasmid, previously considered a defining trait of APEC, is highly prevalent in clinical isolates from diseased turkeys. However, the plasmid is also quite prevalent among cecal E. coli isolates from healthy birds, including both turkeys and broilers. In contrast, we identify distinct differences in clonal backgrounds of turkey clinical versus cecal strains, with a subset of sequence types (STs) dominating the clinical landscape (ST23, ST117, ST131, ST355, and ST428), which are rare within the cecal landscape. Because the same clinical STs have also dominated the broiler landscape, we performed lethality assays using strains from dominant STs from clinical or cecal landscapes in embryonated turkey and chicken eggs. We show that, irrespective of plasmid carriage, dominant clinical STs are significantly more virulent than dominant cecal STs. We present a revised APEC screening tool that incorporates APEC plasmid carriage plus markers for dominant clinical STs. This revised APEC pathotyping tool improves the ability to identify high-risk APEC clones within poultry production systems, and identifies STs of interest for mitigation targets., (Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.)

Published
2022
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147. Sensitivity and Specificity of Rapid Diagnostic Tests for Hepatitis C Virus With or Without HIV Coinfection: A Multicentre Laboratory Evaluation Study.

Author

Vetter BN, Reipold EI, Ongarello S, Audu R, Ige FA, Alkhazashvili M, Chitadze N, Vanroye F, De Weggheleire A, An S, and Fransen K

Subjects
Humans, Hepacivirus, Diagnostic Tests, Routine, Laboratories, Retrospective Studies, Hepatitis C Antibodies, Sensitivity and Specificity, Hepatitis C complications, Hepatitis C diagnosis, HIV Infections epidemiology
Abstract

Background: Hepatitis C virus (HCV) screening is critical to HCV elimination efforts. Simplified diagnostics are required for low-resource settings and difficult-to-reach populations. This retrospective study assessed performance of rapid diagnostic tests (RDTs) for detection of HCV antibodies., Methods: Two lots of 13 RDTs were evaluated at 3 laboratories using archived plasma samples from 4 countries (Nigeria, Georgia, Cambodia, and Belgium). HCV status was determined using 3 reference tests according to a composite algorithm. Sensitivity and specificity were evaluated in HIV-infected and HIV-uninfected populations. Operational characteristics were also assessed., Results: In total, 1710 samples met inclusion criteria. In HIV-uninfected samples (n = 384), the majority of RDTs had sensitivity ≥98% in 1 or both lots and most RDTs had specificity ≥99%. In HIV-infected samples (n = 264), specificity remained high but sensitivity was markedly lower than in HIV-uninfected samples; only 1 RDT reached >95%. The majority of HIV-infected samples for which sensitivity was low did not have detectable HCV viral load/core antigen. Interreader variability, lot-to-lot variability, and rate of invalid runs were low for all RDTs (<2%)., Conclusions: HCV RDTs should be evaluated in the intended target population, as sensitivity can be impacted by population factors such as HIV status., Clinical Trials Registration: NCT04033887., (© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.)

Published
2022
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148. Leading the way together: a cluster randomised controlled trial of the 5R Shared Leadership Program in older adult walking groups.

Author

Fransen K, Cruwys T, Haslam C, Iserbyt P, Seghers J, Vanderlinden J, van Uffelen J, Verbaanderd E, and Boen F

Subjects
Aged, Exercise, Humans, Peer Group, Surveys and Questionnaires, Leadership, Walking
Abstract

Background: With a rapidly ageing society, healthy ageing has become a key challenge. Engagement in physical activity, and particularly walking, is a key strategy that contributes to healthy ageing amongst older adults. The purpose of the present study was to evaluate the efficacy of a group walking program for older adults that incorporates the 5R Shared Leadership Program (5R S ). By implementing a structure of shared leadership and strengthening peer leaders' identity leadership, 5R S aims to cultivate a shared social identity amongst participants, which has in other contexts been associated with greater performance and well-being., Methods: A cluster randomised controlled trial was conducted to test the efficacy of the 5R S group walking program on group identification, group cohesion, walking activity, and well-being, compared to a regular group walking program for older adults. Nineteen older adult walking groups (i.e., the clusters; N = 503; M age  = 69.23 years, SD = 6.68) all participated in a 12-week structured group walking program. Nine walking groups (n = 304) were randomly assigned to the intervention in which participants received the 5R S program in addition to regular group walking., Results: 5R S was successful in strengthening the identity leadership qualities of the appointed peer leaders. Multilevel regressions showed that 5R S succeeded in increasing group cohesion and walking activity to a greater extent than a regular group walking program, while participants' group identification and well-being increased to a similar extent in both conditions. Furthermore, structural equation modelling revealed that group identification mediated the impact of peer leaders' identity leadership on group cohesion and well-being (but not walking activity)., Conclusion: By harnessing the capacity of the group and its peer leaders, the 5R S program offers a promising intervention to engage older adults in physical activity., Trial Registration: The study was retrospectively registered as clinical trial on 9 September 2021 ( NCT05038423 )., (© 2022. The Author(s).)

Published
2022
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149. Athlete Leadership Development Within Teams: Current Understanding and Future Directions.

Author

Cotterill ST, Loughead TM, and Fransen K

Abstract

Leadership has been shown to be a fundamental factor influencing the performance of sport teams. Within these teams, leadership can be provided by coaches, formal athlete leaders, such as team captains, and other 'informal' athlete leaders. The role of the athlete leader in a team, either formal or informal, has been consistently reported over the last 10 years to have a significant impact upon a teams' functioning and effectiveness, as well as teammates' general health and mental wellbeing. As such, cultivating the provision of this leadership within a team has emerged as an important focus for managers, coaches, sport psychologists and scholars alike. While the recognition of the importance of athlete leadership is well established, there has been a lag in the development of systematic approaches to enhance and develop the leadership skills and capabilities of the athletes within sport teams. As a result, this paper seeks to review contemporary examples and current understanding of approaches to athlete leadership development. The paper will also highlight future areas for research and applied practice development., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Cotterill, Loughead and Fransen.)

Published
2022
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150. Does Fair Coach Behavior Predict the Quality of Athlete Leadership Among Belgian Volleyball and Basketball Players: The Vital Role of Team Identification and Task Cohesion.

Author

De Backer M, Van Puyenbroeck S, Fransen K, Reynders B, Boen F, Malisse F, and Vande Broek G

Abstract

A vast stream of empirical work has revealed that coach and athlete leadership are important determinants of sport teams' functioning and performance. Although coaches have a direct impact on individual and team outcomes, they should also strive to stimulate athletes to take up leadership roles in a qualitative manner. Yet, the relation between coach leadership behavior and the extent of high-quality athlete leadership within teams remains underexposed. Based on organizational justice theory and the social identity approach, the present research tested whether perceived justice of the coach positively predicts the quality of athlete leadership. Furthermore, we examined the role of group dynamic processes (i.e., team identification and task cohesion) within this relation. Belgian volleyball ( N = 161) and basketball players ( N = 78) were asked to rate the justice of their coach, their team identification, the task cohesion, and the athlete leadership quality in the team. Structural equation modeling indicated that coaches' perceived justice positively predicted the quality of athletes' leadership, and that this relation was established through three intermediate steps (i.e., from team identification to task cohesion, to athlete leadership quality). These results suggest that fair coach behavior does not only bridge the gap between leadership and followership, it also has the potential to improve the quality of athletes' leadership within sport teams. More specifically, findings suggest that coaches' perceived justice cultivates a shared social identity characterized by high levels of players' identification with their team, which in turn increased their perceptions of the team's task cohesion. Finally, this increased task cohesion encouraged the athlete leaders to demonstrate high-quality leadership., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 De Backer, Van Puyenbroeck, Fransen, Reynders, Boen, Malisse and Vande Broek.)

Published
2022
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