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Тема выпускной работы: «Разработка сайта на React.js и модуля чат для компании ИНФОТЕХ». Данная работа была посвящена разработке на React.js,а так же анализу предприятия ИНФОТЕХ. Задачи которые были решены в ходе разработке: •Проанализировать предприятие ООО «ИНФОТЕХ» и работу его отделов; •Проанализировать задач для разработки проекта; •Проанализировать рынок существующих решений; •Проанализировать целесообразности выполнения проекта; •Реализация проекта; •Тестирование проекта. Для выбора фреймворка и платформы была проведена сравнительная исследовательская работа. В начале стоял выбор фреймворка, на котором мы будем писать сайт для компании ИНФОТЕХ, выбирал я из следующих фреймворков: React.js, Angular, Vue.js. На какой платформе разрабатывать я выбирал из следующих: VS code sublime text 3, PhpStorm. Для создания модуля чат я пользовался API React Slack Chat. Так, как помимо поставленных задач планируется расширение и добавление большего функционала, поэтому это так же сказалось на выборе фреймворка. Так же будет важен пункт тестирования и SEO оптимизация так, как проект будет продвигаться в поисковых системах. В результате проделанной работы я выбрал фреймворк React.js, а так же платформу VS code. Так же были проведены все SEO тесты и Usability тестирование. После чего сайт был опубликован на хостинг под доменом – pascounter.infoteh.ru., The topic of the graduation project: “Development of the website in React.js framework and the chat module for INFOTECH company”. The goal of the project is the development of the React.js-based website as well as the analysis of the structure and functioning of INFOTECH. The milestones of the workplan are: • Detailed analysis of the structure of INFOTECH Ltd. and functioning of its departments • Analysis of the key issues of the development process • Analysis of the market of the existing solutions • Analysis of feasibility and practicability of the project • Project implementation • Product testing A comparative study was done for identification of a suitable framework and platform. React.js, Angular and Vue.js were considered as possible frameworks. The options for the platform were: VS code, sublime text 3, Php Storm. API React Slack Chat was used for the chat module. Choosing the framework, I considered the planned further development of the product. The testing and search engine optimization (SEO) are also important since the product will be used in the web browser applications. As a result, I choose React.js framework and VS code platform. After SEO and Usability testing, the website was published in the hosting under domain pascounter.infotech.ru

Nerve Diseases are one of the most important health issues faced by a majority of the population of the world. They can range from as much as a small tooth sensitivity to more complex nervous diseases like Parkinson's disease or Parkinsonism. It is essential to have a frame work that can effectually recognize the prevalence of Parkinsonism in thousands of samples instantaneously. In this paper the potential of nine classification techniques is evaluated for prediction of Parkinsonism. Namely decision tree, naive Bayesian neural network, SVM, ANN, KNN. The proposed algorithm of SVM (support vector machine) employs in Parkinsonism prediction. Using medical profiles such as age, sex, blood pressure, muscle electric activity, EMG Evaluation, it can predict likeliness of patients getting Parkinsonism. Based on this, medical society takes interest in detecting and preventing the nerve disease. From the analysis, it has been proved that classification based techniques contribute high effectiveness and obtain high accuracy when compared to others.

This paper is devoted to find the feasible shape functions for the construction of static wormhole geometry in the frame work of logarithmic-corrected $R^2$ gravity model. We discuss the asymptotically flat wormhole solutions sustained by the matter sources with anisotropic pressure, isotropic pressure and barotropic pressure. For anisotropic case, we consider three shape functions and evaluate the null energy conditions and weak energy conditions graphically along with their regions. Moreover, for barotropic and isotropic pressures, we find shape function analytically and discuss its properties. For the formation of traversable wormhole geometries, we cautiously choose the values of parameters involved in $f(R)$ gravity model. We show explicitly that our wormhole solutions violates the non-existence theorem even with logarithmic corrections. We discuss all physical properties via graphical analysis and it is concluded that the wormhole solutions with relativistic formalism can be well justified with logarithmic corrections., Comment: 12 pages, 8 figures

Nigeria educational system and economy no doubt have received a lot of criticisms from economic Historians and other scholars who are worried on the declining standard of education and quality of life in the country. This has made the country to be listed as one of the poorest country by Transparent International. The interest of this paper is to do a historical overview of education and standard of life from the date of Nigeria Independence in October 1st 1960 to 2013 and see how valid it is that, poor infrastructural development has affected Nigeria education and Global economy. The paper shall also examine the causes of poor infrastructural development in Nigeria and determine their challenges and look for the appropriate measure to put a stop to the problem. Attempts shall also be made at suggesting a way forward. It is the opinion of this paper that, improvement on the standard of education will help to reduce level of world economic crisis. The work shall adopt normative theoretical frame work in its analysis. It shall also make use of primary and secondary sources as well as eye witness account.

Communication technologies are one of the pivotal technologies which have wider ramifications across multiple domains. Intelligent networks or cognitive radio (CR) is one of the important offshoots...

The soft and rough set theories have a great importance in literature to deal vagueness and uncertainty, but both the theories are unable to deal the vagueness and uncertainty with multipolar information in multi-criteria decision-making. Hybrid models always provide more precise and accurate results in multi-criteria decision making. Thus in this research article, we present a novel frame work for handling multi-criteria decision-making by combining the theory of mF sets with rough sets and soft sets to introduce the novel models called mF rough set model and soft mF rough set model, which approximate the data under multipolar information. Further, we explain the fundamental operations of mF rough sets including union, intersection, composition, and investigate some of their properties. We also study some operations of soft mF rough sets. Moreover, we explore potential applications of mF rough sets and soft mF rough sets in multi-criteria decision-making. We also develop algorithms of our proposed hybrid models to solve multi-criteria decision-making problems.

Epigenetics as a field of study is important because it tends to give answers to pertinent questions like why are identical twins behaving differently despite their possession of the same gene? Epigenetics provides a frame work for solving medical problems like mental retardation, neurodegenerative disorder, schizophrenia and social challenges like suicide and addiction. Abnormal DNA methylation pattern in epigenetics has been linked with a huge number of human cancers. However, recent research has revealed that epigenetic pharmaceuticals like vorinostat, decitabine and azacytidine could be a replacement or aid therapy for presently accepted treatment methods such as radiation and chemotherapy or may argument these current treatments. Understanding epigenetics phenomena entails the use of some research methods which include chromatin immunoprecipitation, fluorescent in-situ hybridization, methylation-sensitive restrictive enzyme and the use of bioinformatics methods. Further research work into epigenetics should be encouraged since this discipline of study has the potential to unravel lots of knowledge that will be very beneficial to managing some medical conditions.

The problem of forest and peatland fires in Riau has become main topic to prioritize its revamping. Land and forest fires in Riau until reached 3,700 hectares area, happened in some last years,.Forest and peatland fires occured in the majority of districts in Riau Province, from low category of 4 hectares until 2,800 hectares. This researchdiscusses aboutanalysis of controlling wirelessTemperature Sensor for monitoring Peat-Land fire by using LM35 Temperature Sensor, Transmitter-Module (HC-12), Receiver-Module (HC-12), Arduino-ProMini to produce outputs on LED, LCD, Buzzer. Detector of Peat-Land fire works when it is burning, so heat will spread through aluminium stalk and be read by Temperature-Sensor1 upto Temperature-Sensor4. Output of each sensor is sent to each control block of Arduino-ProMini in Transmitter-Module(FU1–FU4). From Arduino-ProMini, it is sent toReceiver-Module(FU5). Receiver-Module only receives one data from Transmitter-Module in one time. Every data is received by Receiver-Module goes to Arduino-ProMini, processed to produce outputs on LCD that shows ID of FU1–FU4, Peat-Land Status, temperature of Peat Land. If LED is Green, Peat-Land not burned, LED shows SAFE Condition, Buzzer Off. If LED is Yellow, Peat-Land burned underground, LED shows BE-CAREFUL Condition, Buzzer On. If LED is Red, Peat-Land burned on the ground, LED shows DANGER Condition, Buzzer On. Temperature 0°C–21.9°Cis SAFE Category because Peat-Land not burned. Temperature 22°C–28.4°Cis BE-CAREFUL Category because Peat-Land burned underground. Temperature 28.4°C–50°Cis DANGER Category because Peat-Land burned on the ground. This equipment works as its frame work.

In this work, we have theoretically studied differential cross section (DCS) of Raman scattering of I n x G a 1 − x N / G a N quantum dot (QD) within the frame work of effective-mass approximation at 0K. Numerical calculations show that built-in electric field has a significant influence on the DCS. We find that the change of built-in electric field and parabolic frequencies can induce Raman shifts, and the full width at half maximum (FWHM) of Raman spectrum increases with increasing built-in electric field.

Adhesively bonded composite joints plays, an important role in the modern composite structures assembly to realize light weight structures than the mechanical fastening. However, in the process of adhesive bonding of composite components can result in manufacturing flaws namely debonds. Debonds can change the structural response of adhesively bonded joints significantly in compressively loaded aerospace structures. In general, the prediction of the maximum load that composite structures can withstand is very crucial due to the anisotropic nature of the composite material. The presence of manufacturing defects like debonds adds further complexity to the prediction of failure mechanisms of the composite joints. The present study is focused to ascertain the effective load carrying capacity of the adhesively bonded composite joints in the presence of closed debonds. The finite element method (FEM) is used to predict the onset of initiation of debond growth in conjunction with virtual crack closure technique (VCCT). The studies are carried out for various bonded laminate configurations in the frame work of VCCT using general purpose FE code (ABAQUS). The influence of parameters such as laminate sequence, debond location, size and its shapes (square and circular) are investigated.

The possibility of assessing the equation of state of the neutron star matter using gravitational waves is briefly sketched. The effective theory recently proposed in the frame work of the scale-invariant hidden local symmetry is discussed to demonstrate its particular feature of a change over in EoS from lower density to higher density. The possible implications on the gravitational waves from coalescing binary neutron stars are discussed.

The research findings presented in this article aim at explaining the framework of crisis management in the financial sector of Bosnia and Herzegovina (B&H). This framework is supposed to ensure financial stability even in the circumstances of business failure of institutions, which could cause systematic damage. Based on the critical analysis of market conditions and legal and institutional frameworks established in the B&H, and having in mind the supranational nature of the crisis in the financial sector, the authors argue that an adequate mechanism for a resolution of any crisis situation must be founded on the measures that ensure accountability, transparency, and integrity of all participants in the financial system. Recent legislative initiatives in the EU financial sector have resulted in an innovative framework of crisis management and tremendously comprehensive integration in the field of financial law. For that reason, this research includes also an evaluation of the extent to which elements of this modern European mechanism for dealing with crisis situations in the financial sector are included in the legislative implementation in the fragmented legal and institutional framework of B&H.

For numerical weather prediction over a particular region, it is important to know the best combination of physical parameterizations available in the considered modelling frame work. The main objective of the study is to obtain the best combination of the weather research and forecasting (WRF) model physics for accurately simulating high-impact weather conditions, especially the rainfall over Western and Central Africa. For this purpose, performance of WRF from various simulations with specific configurations is assessed by comparing the results to the Tropical Rainfall Measurement Mission data. Each of the simulations is carried out for 30 h and initialized at 00 UTC. The spin-up time considered for the study is 6 h. A flood event (21–22 July 2010) is simulated by considering five cumulus physics schemes with multiple cloud microphysics, planetary boundary layer and land surface parameterizations. Analysis of the model results indicates that some of the physics combinations have good agreement with observations, especially the new (GFS) simplified Arakawa–Schubert and the modified Tiedtke cumulus parameterizations combined with Thompson and Morrison microphysics. However, most of the combinations over-estimated the rainfall over the study domain, while the simulations with Betts–Miller–Janjic cumulus parameterizations showed negative bias over designated regions of Africa.

For fully nonlinear elliptic boundary value problems in divergence form, improved error estimates are derived in the frame work of a class of expanded discontinuous Galerkin methods. It is shown that the error estimate for the discrete flux in L 2 -norm is of order k + 1 , when piecewise polynomials of degree k ≥ 1 are used to approximate both potential as well as flux variables. Then, solving a discrete linear elliptic problem in each element locally, a suitable post-processing of the discrete potential is proposed and it is proved that the resulting post-processed potential converges with order of convergence k + 2 in L 2 -norm. By choosing stabilizing parameters appropriately, similar results are derived for the expanded HDG methods for nonlinear elliptic problems.

الملخص تأثير الغبار على صحة السکان في منطقة جازان. يعد الغبار من أهم الظواهر البيئية التي تلعب دورا هاما في التأثير على صحة الإنسان, وعليه فقد تناول هذا البحث تأثير الغبار على صحة السکان في منطقة جازان. وقد تمت في مقدمة هذا البحث إبراز مشکلة وأهمية وأهداف الدراسة, وکذلک نبذة موجزة عن منطقة الدراسة, إضافة إلى الإطار النظري والدراسات السابقة والإجراءات المنهجية المتضمنة مصادر البيانات وأساليب تحليها. وقد عمدت الدراسة إلى توضيح العوامل المؤثرة على ظاهرة الغبار في منطقة جازان والتي تأتي في مقدمتها الموقع الفلکي في النطاق شبه المداري, إضافة للعديد من العوامل کالمنخفضات الجوية والتيارات الهوائية والجفاف وطبيعة السطح المفککة وقوة سرعة الرياح إضافة إلى تدهور الغطاء النباتي وبعض الممارسات الخاطئة للسکان. کما عمدت الدراسة إلى تحليل التباين الزماني لظاهرة الغبار في منطقة جازان وذلک خلال الفترة من 1985 إلى 2015م, وإبراز التباين المکاني لهذا التوزيع, إضافة إلى تحليل العلاقة الارتباطية بين حالات الإصابة بمرض حساسية الصدر (الربو) وظاهرة الغبار. وقد اعتمدت الدراسة في هذا البحث على استخدام عدد من الأساليب الإحصائية في تحليل البيانات, مثل معامل ارتباط بيرسون, ومربع کاي, إضافة إلى عدد من الأساليب الکارتوجرافية, مثل الرسوم البيانية وخرائط التوزيع. وقد خلصت الدراسة في خاتمتها إلى عدد من النتائج, من أهمها أن هناک تباين فصلي ومکاني في توزيع ظاهرة الغبار في منطقة جازان, وأن الموقع الفلکي وقوة سرعة الرياح من أکثر العوامل تأثيرا على ظاهرة الغبار بالمنطقة. کما خلصت إلى عدد من التوصيات التي من المؤمل أن تساعد على تقليل تأثير ظاهرة الغبار على صحة السکان في منطقة جازان. Abstract Dust is one of the important environmental phenomenal, which plays an important role influencing human health in Jazan region. This research presenting problem and aim of the study, as well as brief theoretical frame work and previous studies. The study also analyses the factors affecting dust phenomena in Jazan province, In the be sinus or which astrology location in semi tropical region. Beside many factors like spatial variation and air current drought, features of scattered unrelated surface, and speed strong storm. In addition to practices of population. The study relay on analyzing the data from 1985 to 2015, and presenting the spatial variation in Jazan province, In order to understand the relation between the state of taking disease of chest infection and dust phenomena. This study used deferent statistical method such as Like Pearson, Ki square and graphic sketches. Finally, The study has arrived at in the conclusion many outcomes. The most important of these is season and spatial variation in distribution of dust phenomenon, and the location concerning as strong factor effecting dust storm in Jazan province, many recommendation have been presented.

Feminist film theory, with its focus on the representation of women in cinema, sets the stage for feminist film critics to address the distortions on women’s identity in cinema. Little wonder that discourses in feminist film criticism attempt to suggest ways of deconstructing the distortions which are assumed to have resulted from the manipulative influence of male filmmakers. Their efforts in drawing the attention of film scholars to the perpetuation of the negative profiling of the woman’s image in cinema result from the notion that early filmmakers were males who anchored their narratives on a male’s world view. Therefore, to present an objective perspective, there is urging need for a re-definition of women’s roles in cinema. Consequently, they surmised that the lopsided representation of women in cinema by males requires a deconstruction of this trend that undermines the best side of the other sex so as to accommodate a woman-centred ideology: this is in order to harness women’s experiences. This work therefore, encourages the less-favoured sex to take up the fight with more determination to re-write history and change the ordering of regular but infamous dictates of culture and gender themes in film narratives. To this end, the “theory of deconstruction” will serve as the frame work for this study.Keywords: Cinema, feminist film criticism, women filmmakers, manipulation, Stereotype, deconstruction

A CFD model has been implemented to investigate the effects the pipe undulation on sand transport. Of particular interest of the present study is the sand deposition in small angled V-inclined bend relevant to oil and gas subsea flowlines where sand deposition could be a major problem. The model used is the two-fluid Eulerian-Eulerian model with the granular temperature to tackle the solid phase properties. A number of sub-models for tackling solid-fluid and fluid-fluid interaction has been incorporated in the modelling frame work to capture the transition of flow regimes. The simulation results show that the seemingly small angled V-inclined has significant impact on sand disposition compared to the horizontal section. Sand is deposited at the downstream section of the V-inclined pipe at much higher velocities compared to the minimum transport velocity of the horizontal pipe.

A frame work for investigating the best combination of functioning parameters on a variable compression ratio diesel engine is proposed in the present study using a multi attribute optimization methodology, Graph Theory Matrix Approach. The functioning parameters, attributes, sub attributes and functioning variables of sub attributes are chosen based on expert’s opinion and literature review. The directed graphs are developed for attributes and sub attributes. The ‘Parameter Index’ was calculated for all trials to choose the best trial. The experimental results are verified with the theoretical data. Functioning parameters with combination of compression ratio of 17, fuel injection pressure of 20 N/mm2 and fuel injection pressure of 21°bTDC was found to be best. The proposed method allows the decision maker to systematically and logically find the best combination of functioning parameters.

This research reports the findings of a study concerning the acceptance of online banking in Pakistan. It investigates customer's adoption within the context of Pakistan online banking services whereby the research frame work is based on the extension of Technology Acceptance Model. The research model included factors that would influence the acceptance of online banking. The frame work dimensions includes online banking usage, quality of internet connection, perceived enjoyment, perceived usefulness, perceived ease of use and security & privacy. A survey was conducted to gather the data for study. Reliability, correlation and factor analysis were used to analyse the data. Results showed that quality of internet connection, amount of information on online banking and security and privacy has positive influence on online banking usage. Theoretical contributions and practical implications of the findings are discussed in the paper and suggestions for future research are proposed.

Lightweight frame is very important to engineering machinery. In this paper, a lightweight design method is proposed for a mechanical mowing truck frame. This method combines topological optimization with topology optimization to design the frame successfully. Based on the finite element simulation, the strength analysis of the two working conditions (bending condition and torsion condition) for the mowing vehicle frame is carried out on the basis of satisfying the requirements of the frame work strength. This paper makes a comparative analysis of the frame after the second optimization using the combined method proposed. The comparison results show that the optimized frame meets the strength requirement, and its quality is 34.3% lower than before. The lightweight effect is obvious.

Monuments documentation process consider one of the most important pillars of conservation, the most common issue about documentation that it just used while the restoration project starts, but the correct approach that it is a continuous process till it reach to a complete monitoring operation, this operation was very hard before documentation technology appears, which minimized the time and effort spent in documentation, in addition to its precise results which helped in decision making for restoration and conservation as a whole, the study depends on action research method to evaluate using technology in documentation between theory and practice, the outcome result is a frame work of using technology in documentation evaluation to reveal how useful is using documentation done through technology in prioritizing intervention of restoration and conservation.

In response to the projected nursing shortage, Florida law makers made modifications to the law in 2009 that changed the Board of Nursing’s approval and monitoring process for nursing education programs. As a result, the number of approved nursing programs in Florida increased from 171 to 350 (105%) which resulted in the proliferation of poor nursing programs with low graduation and NCLEX pass rates. Prospective students are challenged to distinguish reputable nursing programs from problematic institutions. The purpose of this project was to create a centralized web-based platform and evaluate the ability of the platform to increase knowledge in prospective nursing students, regarding credible nursing programs. The project was implemented using the Knowledge to Action Frame Work. To test the effectiveness and knowledge gain, twenty seven prospective nursing students agreed to examine all components of the website. Based on the analysis, post questionnaire scores were overall higher than pre-questionnaire scores which showed an increase in knowledge. In the future, the project could expand to include free online classes such as, medical terminology, medical error, and staying healthy through nursing school. Key words: , , , , , .

Nowadays marine pollution become a serious problem in the world espesially in Indonesia. Marine scientists have found harmful impact of marine pollution to marine environment, ecosystem and humans, there-quarter of all marine debris is plastic, a persistent and potentially hazardous pollutan. Plastic can be chemically harmful to wildlife, either because themselves potentially toxic or other toxic pollutan, the situation become worse when it come to marrine pollution caused by micro plastic, micro plastic is very dangerous for the ecosystem and the human in the world. Public awaarness to participate in maintaining the marine environment is decreasing day by day. Some people do not realise that microplastic are so danger to marine environment because most plastics in the ocean break up into very small particles, plastic is one of the kind of marine debris and it can come in all shapes and size, but those that are less than five millimeter in length . Indonesia is the second-biggest-contributor to ocean after China, with some estimates suggesting it is source of about 10% of global plastic pollution, if this problem can not be solved, there could be more plastic than fish in the ocean. Unfortunetly up to present we do not have any effective methode to clean up the ocean, the only thing that we can do is reduce the use of plastic in daily life. Marine pollution is become global problem so that is why we need some strategies to solved this problem, based on internatinal frame work Indonesia and others contries should do cooperation with others country and based on national legal frame works government should make special regulation to protect marine environment. Pollution from land-based sources, either direcly by urban or argiculuture discharger or indirecly through water. Keyword: Marrine, Pollution, ASEAN

In the frame work of the perturbed restricted three-body problem, the solutions of halo orbits are developed up to fifth order approximation by using Lindstedt–Poincare technique. The effect of oblateness of the more massive primary on the size, location and period of halo orbits around L 1 and L 2 are studied by considering the Earth–Moon system. Due to oblateness of the Earth, halo orbits around L 1 and L 2 enlarge and move towards the Moon. Also, the period of halo orbits around L 1 and L 2 decreases. Numerical solution for halo orbits around L 1 and L 2 in the Sun–Earth system is obtained by using the differential correction method for different values of radiation pressure and oblateness. The separation between the orbits obtained using fourth and fifth order Lindstedt–Poincare method as well as differential correction method is found to be less than the separation between the orbits obtained using third and fourth order Lindstedt–Paincare as well as differential correction method. This indicates that as the order of the solution increases the separation between consecutive solution decreases leading to more accurate solution.

The research aims to study the effect of the elements of consistency in the text cohesion through the selected text from the" Akbar abialgasim alzagagy" book, to detect what is possible of the secrets of the artistic languor based on the linguistic objective foundations (rules, this has been through several axe. The study has two axes. The first axis is devoted to the theoretical frame work in which the researcher defined the text, coherence and consistency and it's components, The second come to apply these elements to a text was chosen from “Akbar abilgasim alzagagy” book. The study reached the following findings. The study reached several conclusions, including that because of the various means of consistency the indicative unity of the text is achieved and brought together between its many sentences and inter dependence property owned by these means. The study found that more elements of consistency limitation to text clips assignments, specially indicative assignment indicative element. The ability to high light the most indicative personalized elements are pronouns. Not only this but that the vole of the deletion on the grounds that it is most important means of consistency in the text because of the optimal investment in pronoun assignments which is used as alternative of repeating the subject special the subject of.

In this article we present the reflections of different research of works in the educational field, where the gender perspective is privileged. Those Projects are based on the analysis of the experiences of students and teachers in relation to the Integral Sexual Education, in the formation in the Professorate of Primary School at the Institute of Teaching Formation, in the city of San Carlos de Bariloche. The seminar of Sexuality and Gender was established on a case studio through the analysis of the register of participant observation, conversations and interpretation of students realized in different workshops, since 2011 to 2016. The interventions of education in this case were related with the representations and images about the young bodies, sexuality and the relationships of gender. The reflections of this experience of the practice, the relats and other estheticprodutions of the students intertwined with the theorical frame work are some of the contribution that we develop in this article.

Planning and executing the restorative rehabilitation of a severely mutilated dentition is one of the most challenging tasks for the restorative dentist. This case report illustrates an interdisciplinary approach in the treatment of a multifaceted case of partial loss of teeth. A series of provisional prosthesis were used before the final treatment due to extreme complexity of the patient situation. The final treatment was composed of innovatively designed thimble copings, telescopic retainer and cast metal frame work for the rehabilitation of the maxillary and mandibular arch.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, page: 222-226

A new class of 3′-deoxy-3β′-fluoro-3α′-C-hydroxymethyl-pyrimidine 1a-c and purine 1d nucleosides were synthesized using modified Corey-Link reaction with 3-oxo- d -glucofuranose derivative to get C-3 quaternary carbon with 3β′-fluoro-3α′-C-hydroxymethyl groups, in the sugar frame work. Conformational preferences of fluorinated nucleosides were studied by the DFT calculations. Anti-proliferative activity of nucleosides 1a-d was tested against MDA-MB-231, L-132, HeLa and neural cell lines and found to be moderate active.

On the basis of the spatial model, the researches of stress-strain state of a two-story building from low-strength material for substantiate the effectiveness of the installation frame were fulfilled. The frame helps to reduce the stress and strain in the load-bearing structures and ensures reliable operation housing in areas with high seismicity. The choice of physical- and-mechanical characteristics for the material of brickwork is realized on the basis of natural experiments. Two models are considered: with strengthening and without strengthening of the walls by the frame. Analysis of a box-typed structure is carried out numerically by FEM.

This paper is focused on the analysis of categorical data in a 2 × c × K contingency table. The theoretical frame work of a 2 × c design is extended to 2 × c × K with provision for testing interactions among subsets of either lower or upper columns of the designated table. The developed chi square tests for the total interactions as well as for the partitions are shown to be significant and the degrees of freedom additive.

The molecule, 4-(Methylsulfonyl)piperazin-1-ium 2,4,6-trinitrophenolate is crystallized in the monoclinic crystal system under space group P21/c and with unit cell parameters a = 6.951(5) A, b = 21.915(16) A, c = 11.566(7) A, β = 110.9(3)° and Z = 4. The crystal and molecular structure of the molecule was stabilized by hydrogen bond interactions, N—H···O and C—H···O and were visualized through the Hirshfeld surface analysis.

Investigation in perturbative string theory and quantum gravity suggest that there is a measurable minimal length in nature. In this work, according to generalized uncertainty principle, we study the statistical characteristics of Klein–Gordon Oscillator (KLO). The modified energy spectrum of the KLO are obtained. The generalized thermodynamical quantities of the KLO such as partition function, mean energy and entropy are calculated by using the modified energy spectrum.

Exchange couplings in Sr2CrNO6 (N = Os, Ir) Double Perovskites (DPs) have been calculated numerically by using a Monte Carlo Simulation (MCS) in the frame work of Ising model by means of a relation between internal energy per site and magnetization per site. Two model parameters α and α ' have been proposed for Sr2CrOsO6 and Sr2CrIrO6, respectively. The exchange couplings have been computed by varying α and α ' through a MCS to find their values corresponding to the transition temperature 725K specific to Sr2CrOsO6 and 884 K specific to Sr2CrIrO6. The exchange couplings J C r − O s = − 35.201 m e V , J C r − C r = 5.452 m e V and J O s − O s = 14.873 m e V have been obtained for Sr2CrOsO6, while J C r − I r = − 24.464 m e V , J C r − C r ' = 2.181 m e V and J I r − I r = 16.730 m e V have been obtained for Sr2CrIrO6. Magnetization and magnetic susceptibility have been investigated in both compounds. Internal energy per site has been given.

Quantum Brownian motion of a rod-like particle is investigated in the frame work of system plus reservoir model. The quantum mechanical and classical limit for both translational and rotational motions are discussed. Correlation functions, fluctuation-dissipation relations and mean squared values of translational and rotational motions are obtained.

Higher-dimensional tilted Bianchi type-I cosmological model is investigated in the frame work of Lyra (Math Z 54:52, 1951) Geometry. Exact solutions to the field equations are derived when the metric potentials are functions of cosmic time only. Some physical and geometrical properties of the solutions are also discussed.