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103. Predictors of Prolonged Fluoroscopy Exposure in Pediatric Endoscopic Retrograde Cholangiopancreatography: Results From the Large Pediatric Endoscopic Retrograde Cholangiopancreatography Database Initiative Multicenter Cohort

Author

Liu, Quin Y., primary, Ruan, Wenly, additional, Fishman, Douglas S., additional, Barth, Bradley A., additional, Tsai, Cynthia Man-Wai, additional, Giefer, Matthew J., additional, Kim, Kyung Mo, additional, Martinez, Mercedes, additional, Dall’Oglio, Luigi, additional, De Angelis, Paola, additional, Torroni, Filippo, additional, Faraci, Simona, additional, Bitton, Sam, additional, Wilsey, Michael, additional, Khalaf, Racha T., additional, Werlin, Steven, additional, Dua, Kulwinder, additional, Huang, Clifton, additional, Gugig, Roberto, additional, Mamula, Petar, additional, Fox, Victor L., additional, Grover, Amit S., additional, Quiros, J. Antonio, additional, Zheng, Yuhua, additional, and Troendle, David M., additional

Published
2021
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105. Analysis of INSPPIRE-2 Cohort: Risk Factors and Disease Burden in Children With Acute Recurrent or Chronic Pancreatitis.

Author

Uc, Aliye, Cress, Gretchen A., Wang, Fuchenchu, Abu-El-Haija, Maisam, Ellery, Kate M., Fishman, Douglas S., Gariepy, Cheryl E., Gonska, Tanja, Lin, Tom K., Liu, Quin Y., Mehta, Megha, Maqbool, Asim, McFerron, Brian A., Morinville, Veronique D., Ooi, Chee Y., Perito, Emily R., Schwarzenberg, Sarah Jane, Sellers, Zachary M., Serrano, Jose, and Shah, Uzma

Published
2022
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106. Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopic Procedures: A Joint NASPGHAN/ESPGHAN Guideline

Author

Lightdale, Jenifer R., primary, Walsh, Catharine M., additional, Oliva, Salvatore, additional, Jacobson, Kevan, additional, Huynh, Hien Q., additional, Homan, Matjaž, additional, Hojsak, Iva, additional, Gillett, Peter M., additional, Furlano, Raoul I., additional, Fishman, Douglas S., additional, Croft, Nicholas M., additional, Brill, Herbert, additional, Bontems, Patrick, additional, Amil-Dias, Jorge, additional, Utterson, Elizabeth C., additional, Tavares, Marta, additional, Rosh, Joel R., additional, Riley, Matthew R., additional, Narula, Priya, additional, Mamula, Petar, additional, Mack, David R., additional, Liu, Quin Y., additional, Lerner, Diana G., additional, Leibowitz, Ian H., additional, Otley, Anthony R., additional, Kramer, Robert E., additional, Ambartsumyan, Lusine, additional, Connan, Veronik, additional, McCreath, Graham A., additional, and Thomson, Mike A., additional

Published
2021
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107. Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopy Facilities: A Joint NASPGHAN/ESPGHAN Guideline

Author

Lightdale, Jenifer R., primary, Walsh, Catharine M., additional, Narula, Priya, additional, Utterson, Elizabeth C., additional, Tavares, Marta, additional, Rosh, Joel R., additional, Riley, Matthew R., additional, Oliva, Salvatore, additional, Mamula, Petar, additional, Mack, David R., additional, Liu, Quin Y., additional, Lerner, Diana G., additional, Leibowitz, Ian H., additional, Jacobson, Kevan, additional, Huynh, Hien Q., additional, Homan, Matjaž, additional, Hojsak, Iva, additional, Gillett, Peter M., additional, Furlano, Raoul I., additional, Fishman, Douglas S., additional, Croft, Nicholas M., additional, Brill, Herbert, additional, Bontems, Patrick, additional, Amil-Dias, Jorge, additional, Kramer, Robert E., additional, Ambartsumyan, Lusine, additional, Otley, Anthony R., additional, McCreath, Graham A., additional, Connan, Veronik, additional, and Thomson, Mike A., additional

Published
2021
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108. Pediatric Endoscopy Quality Improvement Network Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline

Author

Walsh, Catharine M., primary, Lightdale, Jenifer R., additional, Fishman, Douglas S., additional, Furlano, Raoul I., additional, Mamula, Petar, additional, Gillett, Peter M., additional, Narula, Priya, additional, Hojsak, Iva, additional, Oliva, Salvatore, additional, Homan, Matjaž, additional, Riley, Matthew R., additional, Huynh, Hien Q., additional, Rosh, Joel R., additional, Jacobson, Kevan, additional, Tavares, Marta, additional, Leibowitz, Ian H., additional, Utterson, Elizabeth C., additional, Croft, Nicholas M., additional, Mack, David R., additional, Brill, Herbert, additional, Liu, Quin Y., additional, Bontems, Patrick, additional, Lerner, Diana G., additional, Amil-Dias, Jorge, additional, Kramer, Robert E., additional, Otley, Anthony R., additional, Ambartsumyan, Lusine, additional, Connan, Veronik, additional, McCreath, Graham A., additional, and Thomson, Mike A., additional

Published
2021
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109. Overview of the Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopy: A Joint NASPGHAN/ESPGHAN Guideline

Author

Walsh, Catharine M., primary, Lightdale, Jenifer R., additional, Mack, David R., additional, Amil-Dias, Jorge, additional, Bontems, Patrick, additional, Brill, Herbert, additional, Croft, Nicholas M., additional, Fishman, Douglas S., additional, Furlano, Raoul I., additional, Gillett, Peter M., additional, Hojsak, Iva, additional, Homan, Matjaž, additional, Huynh, Hien Q., additional, Jacobson, Kevan, additional, Leibowitz, Ian H., additional, Lerner, Diana G., additional, Liu, Quin Y., additional, Mamula, Petar, additional, Narula, Priya, additional, Oliva, Salvatore, additional, Riley, Matthew R., additional, Rosh, Joel R., additional, Tavares, Marta, additional, Utterson, Elizabeth C., additional, Ambartsumyan, Lusine, additional, Otley, Anthony R., additional, Kramer, Robert E., additional, Connan, Veronik, additional, McCreath, Graham A., additional, and Thomson, Mike A., additional

Published
2021
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110. Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopists and Endoscopists in Training: A Joint NASPGHAN/ESPGHAN Guideline

Author

Walsh, Catharine M., primary, Lightdale, Jenifer R., additional, Leibowitz, Ian H., additional, Lerner, Diana G., additional, Liu, Quin Y., additional, Mack, David R., additional, Mamula, Petar, additional, Narula, Priya, additional, Oliva, Salvatore, additional, Riley, Matthew R., additional, Rosh, Joel R., additional, Tavares, Marta, additional, Utterson, Elizabeth C., additional, Amil-Dias, Jorge, additional, Bontems, Patrick, additional, Brill, Herbert, additional, Croft, Nicholas M., additional, Fishman, Douglas S., additional, Furlano, Raoul I., additional, Gillett, Peter M., additional, Hojsak, Iva, additional, Homan, Matjaž, additional, Huynh, Hien Q., additional, Jacobson, Kevan, additional, Ambartsumyan, Lusine, additional, Otley, Anthony R., additional, Kramer, Robert E., additional, McCreath, Graham A., additional, Connan, Veronik, additional, and Thomson, Mike A., additional

Published
2021
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111. A prospective multicenter analysis from the Pediatric ERCP Database Initiative: predictors of choledocholithiasis at ERCP in pediatric patients

Author

Fishman, Douglas S., primary, Barth, Brad, additional, Man-Wai Tsai, Cynthia, additional, Giefer, Matthew J., additional, Martinez, Mercedes, additional, Wilsey, Michael, additional, Khalaf, Racha T., additional, Liu, Quin Y., additional, DeAngelis, Paola, additional, Torroni, Filippo, additional, Faraci, Simona, additional, and Troendle, David M., additional

Published
2021
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112. ASGE guideline on the management of cholangitis

Author

Buxbaum, James L., primary, Buitrago, Carlos, additional, Lee, Alice, additional, Elmunzer, Badih Joseph, additional, Riaz, Ahsun, additional, Ceppa, Eugene P., additional, Al-Haddad, Mohammed, additional, Amateau, Stuart K., additional, Calderwood, Audrey H., additional, Fishman, Douglas S., additional, Fujii-Lau, Larissa L., additional, Jamil, Laith H., additional, Jue, Terry L., additional, Kwon, Richard S., additional, Law, Joanna K., additional, Lee, Jeffrey K., additional, Naveed, Mariam, additional, Pawa, Swati, additional, Sawhney, Mandeep S., additional, Schilperoort, Hannah, additional, Storm, Andrew C., additional, Thosani, Nirav C., additional, Qumseya, Bashar J., additional, and Wani, Sachin, additional

Published
2021
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113. ASGE guideline on the role of endoscopy in the management of malignant hilar obstruction

Author

Qumseya, Bashar J., primary, Jamil, Laith H., additional, Elmunzer, Badih Joseph, additional, Riaz, Ahsun, additional, Ceppa, Eugene P., additional, Thosani, Nirav C., additional, Buxbaum, James L., additional, Storm, Andrew C., additional, Sawhney, Mandeep S., additional, Pawa, Swati, additional, Naveed, Mariam, additional, Lee, Jeffrey K., additional, Law, Joanna K., additional, Kwon, Richard S., additional, Jue, Terry L., additional, Fujii-Lau, Larissa L., additional, Fishman, Douglas S., additional, Calderwood, Audrey H., additional, Amateau, Stuart K., additional, Al-Haddad, Mohammed, additional, and Wani, Sachin, additional

Published
2021
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114. Angiosarcoma of the Pancreas in a Pediatric Patient With an Activating KDR-Internal Tandem Duplication: A Case Report and Review of the Literature

Author

Whitlock, Richard S., primary, Ebare, Kingsley, additional, Cheng, Lily S., additional, Fishman, Douglas S., additional, Mills, Joseph L., additional, Nguyen, HaiThuy N., additional, Nuchtern, Jed G., additional, Ruan, Wenly, additional, Smith, Valeria E., additional, Patel, Kalyani A., additional, Fisher, Kevin E., additional, and Vasudevan, Sanjeev A., additional

Published
2021
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115. Vascular Complications in Pediatric Pancreatitis: A Case Series

Author

Dike, Chinenye R., primary, Cress, Gretchen, additional, Fishman, Douglas S., additional, Gonska, Tanja, additional, Ooi, Chee Y., additional, Perito, Emily R., additional, Troendle, David, additional, Tsai, Cynthia M., additional, Lowe, Mark E., additional, and Uc, Aliye, additional

Published
2021
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117. ID: 3526084 INTERNATIONAL CONSENSUS ON PEDIATRIC ENDOSCOPY REPORTING ELEMENTS: A REPORT FROM THE PEDIATRIC ENDOSCOPY QUALITY IMPROVEMENT NETWORK (PENQUIN)

Author

Lightdale, Jenifer R., primary, Walsh, Catharine M., additional, Mack, David R., additional, Utterson, Elizabeth C., additional, Tavares, Marta, additional, Rosh, Joel R., additional, Riley, Matthew R., additional, Oliva, Salvatore, additional, Mamula, Petar, additional, Narula, Priya, additional, Liu, Quin, additional, Lerner, Diana G., additional, Leibowitz, Ian H., additional, Jacobson, Kevan, additional, Huynh, Hien Q., additional, Homan, Matjaz, additional, Hojsak, Iva, additional, Gillett, Peter M., additional, Furlano, Raoul I., additional, Fishman, Douglas S., additional, Croft, Nicholas M., additional, Brill, Herbert, additional, Bontems, Patrick, additional, Amil, Jorge, additional, Kramer, Robert, additional, Ambartsumyan, Lusine, additional, Otley, Anthony R., additional, McCreath, Graham, additional, Connan, Veronik, additional, and Thomson, Mike A., additional

Published
2021
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121. Pediatric chronic pancreatitis without prior acute or acute recurrent pancreatitis: A report from the INSPPIRE consortium

Author

Abu-El-Haija, Maisam, Lowe, Mark, Barth, Bradley, Bellin, Melena D., Fishman, Douglas S., Freedman, Steve, Gariepy, Cheryl, Giefer, Matthew J., Gonska, Tanja, Heyman, Melvin B., Himes, Ryan, Husain, Sohail, Lin, Tom K., Liu, Quin, Mascarenhas, Maria R., Maqbool, Asim, McFerron, Brian, Morinville, Veronique, Nathan, Jaimie, Ooi, Chee Y., Perito, Emily, Pohl, John F., Schwarzenberg, Sarah Jane, Shah, Uzma, Troendle, David, Werlin, Steven, Wilschanski, Michael, Zimmerman, Bridget, and Uc, Aliye

Published
2020
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128. Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant

Author

MacFarland, Suzanne P., primary, Ebrahimzadeh, Jessica E., additional, Zelley, Kristin, additional, Begum, Lubna, additional, Bass, Lee M., additional, Brand, Randall E., additional, Dudley, Beth, additional, Fishman, Douglas S., additional, Ganzak, Amanda, additional, Karloski, Eve, additional, Latham, Alicia, additional, Llor, Xavier, additional, Plon, Sharon, additional, Riordan, Mary K., additional, Scollon, Sarah R., additional, Stadler, Zsofia K., additional, Syngal, Sapna, additional, Ukaegbu, Chinedu, additional, Weiss, Jennifer M., additional, Yurgelun, Matthew B., additional, Brodeur, Garrett M., additional, Mamula, Petar, additional, and Katona, Bryson W., additional

Published
2021
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129. ASGE guideline on the role of endoscopy in the management of benign and malignant gastroduodenal obstruction

Author

Jue, Terry L., primary, Storm, Andrew C., additional, Naveed, Mariam, additional, Fishman, Douglas S., additional, Qumseya, Bashar J., additional, McRee, Autumn J., additional, Truty, Mark J., additional, Khashab, Mouen A., additional, Agrawal, Deepak, additional, Al-Haddad, Mohammed, additional, Amateau, Stuart K., additional, Buxbaum, James L., additional, Calderwood, Audrey H., additional, DeWitt, John, additional, DiMaio, Christopher J., additional, Fujii-Lau, Larissa L., additional, Gurudu, Suryakanth R., additional, Jamil, Laith H., additional, Kwon, Richard S., additional, Law, Joanna K., additional, Lee, Jeffrey K., additional, Pawa, Swati, additional, Sawhney, Mandeep S., additional, Thosani, Nirav C., additional, Yang, Julie, additional, and Wani, Sachin B., additional

Published
2021
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131. Contributors

Author

A-Kader, H. Hesham, primary, Ali, Sabina, additional, Alkhouri, Naim, additional, Alonso, Estella M., additional, Ammoury, Rana, additional, Arca, Marjorie J., additional, Atlas, Arthur B., additional, Auricchio, Salvatore, additional, Baker, Robert D., additional, Baker, Susan S., additional, Baron, Todd H., additional, Barth, Brad, additional, Bass, Dorsey M., additional, Bishop, Phyllis R., additional, Blanchard, Samra S., additional, Chiu, Louisa W., additional, Christie, Dennis L., additional, Cohen, Gail M., additional, Cohen, Mitchell B., additional, Cohen, Stanley A., additional, Conkin, Claudia, additional, Coran, Arnold G., additional, Cushman, Laura L., additional, Bousvaros, Athos, additional, Boyle, John T., additional, Bruch, Steven W., additional, Campbell, Brendan T., additional, Capizzani, Anthony, additional, Carter-Kent, Christine, additional, Caty, Michael G., additional, El-Youssef, Mounif, additional, Emerick, Karan McBride, additional, Evans, Jonathan, additional, Fawaz, Rima, additional, Feldstein, Ariel E., additional, Finn, Laura S., additional, Fishman, Douglas S., additional, Czinn, Steven J., additional, Devadason, David, additional, Di Lorenzo, Carlo, additional, Dohil, Ranjan, additional, Dokler, Maryanne L., additional, Dubinsky, Marla, additional, Eghtesad, Bijan, additional, Ehrlich, Peter F., additional, Garza, José M., additional, Gauderer, Michael W.L., additional, George, Donald E., additional, Ghishan, Fayez K., additional, Gilger, Mark A., additional, Gillespie, Laura, additional, Gleghorn, Elizabeth, additional, Fitzgerald, Joseph F., additional, Fleisher, David R., additional, Fridge, Jacqueline L., additional, Friedlander, Joel, additional, Fuentebella, Judy, additional, Fung, John J., additional, Garcia, Jennifer, additional, Garcia-Naveiro, Reinaldo, additional, Gourley, Glenn R., additional, Grand, Richard J., additional, Gulati, Reema, additional, Gupta, Sandeep K., additional, Hadžic´, Nedim, additional, Hassall, Eric, additional, Heubi, James E., additional, Hupertz, Vera F., additional, Husain, Sohail Z., additional, Hussey, Séamus, additional, Hyams, Jeffrey S., additional, Hyer, Warren, additional, Hyman, Paul E., additional, Iben, Sabine, additional, Iyer, Kishore R., additional, Kuhn, Benjamin R., additional, Levitt, Marc A., additional, Lewis, Shane D., additional, Li, Bu K., additional, Liacouras, Chris A., additional, Little, Danny C., additional, Jonas, Maureen M., additional, Jones, Nicola L., additional, Kaplan, Barbara, additional, Kaufman, Stuart S., additional, Kay, Marsha, additional, Kelly, Deirdre, additional, Kocoshis, Samuel A., additional, Markowitz, Jonathan E., additional, Mascarenhas, Maria R., additional, Mattei, Peter, additional, McLin, Valérie A., additional, Mezoff, Adam G., additional, Mieli-Vergani, Giorgina, additional, Miller, Tracie L., additional, Loening-Baucke, Vera, additional, Loomes, Kathleen M., additional, Lowe, Mark E., additional, Magnuson, David K., additional, Mahajan, Lori A., additional, Mamula, Petar, additional, Markowitz, James F., additional, Mohr, Franziska, additional, Montgomery, Robert K., additional, Motil, Kathleen J., additional, Murch, Simon, additional, Murray, Karen F., additional, Naon, Hillel, additional, Navathe, Aruna S., additional, Ng, Vicky Lee, additional, Nightingale, Scott, additional, Nowicki, Michael J., additional, Nurko, Samuel, additional, Oldham, Keith T., additional, Peña, Alberto, additional, Petras, Robert E., additional, Pfefferkorn, Marian D., additional, Phillips, Sarah M., additional, Qualia, Cary, additional, Rabizadeh, Shervin, additional, Radhakrishnan, Kadakkal, additional, Rodriguez, Leonel, additional, Rodriguez, Ricardo, additional, Rome, Ellen S., additional, Rosh, Joel R., additional, Rudolph, Colin D., additional, Saad, Daniel F., additional, Saeed, Shehzad A., additional, Saleem, Atif, additional, Sandhu, Bhupinder, additional, Saps, Miguel, additional, Sato, Thomas T., additional, Shashidhar, Harohalli, additional, Shroyer, Noah F., additional, Skelton, Joseph, additional, Smith, Lesley, additional, Sogawa, Hiroshi, additional, Soldes, Oliver S., additional, Sood, Manu R., additional, Steffen, Rita, additional, Sullivan, Kara M., additional, Sundaram, Shikha S., additional, Sunku, Bhanu K., additional, Sylvester, Francisco A., additional, Taminiau, Jan, additional, Teitelbaum, Jonathan E., additional, Thomas, Daniel W., additional, Thomson, Mike A., additional, Tolia, Vasundhara, additional, Treem, William R., additional, Troncone, Riccardo, additional, Turkish, Aaron, additional, Udall, John N., additional, Vandenplas, Yvan, additional, Veereman-Wauters, Gigi, additional, Wahbeh, Ghassan T., additional, Wallace, Elizabeth C., additional, Walsh, R. Matthew, additional, Wieckowska, Anna, additional, Winans, Charles G., additional, Wyllie, Robert, additional, Yamout, Sani Z., additional, and Yazigi, Nada, additional

Published
2011
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134. Predictors of Prolonged Fluoroscopy Exposure in Pediatric Endoscopic Retrograde Cholangiopancreatography: Results From the Large Pediatric Endoscopic Retrograde Cholangiopancreatography Database Initiative Multicenter Cohort.

Author

Liu, Quin Y., Ruan, Wenly, Fishman, Douglas S., Barth, Bradley A., Tsai, Cynthia Man-Wai, Giefer, Matthew J., Kim, Kyung Mo, Martinez, Mercedes, Dall'Oglio, Luigi, De Angelis, Paola, Torroni, Filippo, Faraci, Simona, Bitton, Sam, Wilsey, Michael, Khalaf, Racha T., Werlin, Steven, Dua, Kulwinder, Huang, Clifton, Gugig, Roberto, and Mamula, Petar

Published
2022
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143. Web-based cognitive-behavioral intervention for pain in pediatric acute recurrent and chronic pancreatitis: Protocol of a multicenter randomized controlled trial from the study of chronic pancreatitis, diabetes and pancreatic cancer (CPDPC)

Author

Palermo, Tonya M., primary, Murray, Caitlin, additional, Aalfs, Homer, additional, Abu-El-Haija, Maisam, additional, Barth, Bradley, additional, Bellin, Melena D., additional, Ellery, Kate, additional, Fishman, Douglas S., additional, Gariepy, Cheryl E., additional, Giefer, Matthew J., additional, Goday, Praveen, additional, Gonska, Tanja, additional, Heyman, Melvin B., additional, Husain, Sohail Z., additional, Lin, Tom K., additional, Liu, Quin Y., additional, Mascarenhas, Maria R., additional, Maqbool, Asim, additional, McFerron, Brian, additional, Morinville, Veronique D., additional, Nathan, Jaimie D., additional, Ooi, Chee Y., additional, Perito, Emily R., additional, Pohl, John F., additional, Schwarzenberg, Sarah Jane, additional, Sellers, Zachary M., additional, Serrano, Jose, additional, Shah, Uzma, additional, Troendle, David, additional, Zheng, Yuhua, additional, Yuan, Ying, additional, Lowe, Mark, additional, and Uc, Aliye, additional

Published
2020
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144. Diabetes Mellitus in Children with Acute Recurrent and Chronic Pancreatitis: Data from the INSPPIRE Cohort

Author

Bellin, Melena D, Lowe, Mark, Zimmerman, M Bridget, Wilschanski, Michael, Werlin, Steven, Troendle, David M, Shah, Uzma, Schwarzenberg, Sarah J, Pohl, John F, Perito, Emily, Ooi, Chee Yee, Nathan, Jaimie D, Morinville, Veronique D, McFerron, Brian A, Mascarenhas, Maria R, Maqbool, Asim, Liu, Quin, Lin, Tom K, Husain, Sohail Z, Himes, Ryan, Heyman, Melvin B, Gonska, Tanja, Giefer, Matthew J, Gariepy, Cheryl E, Freedman, Steven D, Fishman, Douglas S, Barth, Bradley, Abu-El-Haija, Maisam, and Uc, Aliye

Subjects
Male, acute pancreatitis, Adolescent, Databases, Factual, Global Health, Autoimmune Disease, Medical and Health Sciences, Article, Cohort Studies, Databases, Rare Diseases, Clinical Research, Risk Factors, Pancreatitis, Chronic, pediatric pancreatitis, Diabetes Mellitus, Prevalence, 2.1 Biological and endogenous factors, Humans, Aetiology, Chronic, Child, Metabolic and endocrine, Factual, Nutrition, Pediatric, hereditary pancreatitis, islet, Gastroenterology & Hepatology, Prevention, Diabetes, Diabetes Mellitus, Type 2, Pancreatitis, Acute Disease, Female, Digestive Diseases, Type 2, 2.4 Surveillance and distribution
Abstract

OBJECTIVES:Adults with chronic pancreatitis (CP) have a high risk for developing pancreatogenic diabetes mellitus (DM), but little is known regarding potential risk factors for DM in children with acute recurrent pancreatitis (ARP) or CP. We compared demographic and clinical features of children with ARP or CP, with and without DM, in the INternational Study Group of Pediatric Pancreatitis: In Search of a CuRE (INSPPIRE) registry. METHODS:We reviewed the INSPPIRE database for the presence or absence of physician-diagnosed DM in 397 children, excluding those with total pancreatectomy with islet autotransplantation, enrolled from August 2012 to August 2017. Patient demographics, body mass index percentile, age at disease onset, disease risk factors, disease burden, and treatments were compared between children with DM (n = 24) and without DM (n = 373). RESULTS:24 children (6.0% of the cohort) had a diagnosis of DM. Five of 13 tested were positive for beta cell autoantibodies. The DM group was 4.2 years (95% CI 3.0, 5.4) older at first episode of acute pancreatitis, and tended to more often have hypertriglyceridemia (odds ratio (OR) 5.21 (1.33, 17.05)), coexisting autoimmune disease (OR 3.94 (0.88, 13.65)) or pancreatic atrophy (OR 3.64 (1.13, 11.59)). CONCLUSIONS:Pancreatic atrophy may be more common among children with DM, suggesting more advanced exocrine disease. However, data in this exploratory cohort also suggest increased autoimmunity and hypertriglyceridemia in children with DM, suggesting that risk factors for Type 1 and Type 2 DM respectively may play a role in mediating DM development in children with pancreatitis.

Published
2019

145. Risk Factors for Rapid Progression From Acute Recurrent to Chronic Pancreatitis in Children: Report From INSPPIRE.

Author

Liu, Quin Y, Liu, Quin Y, Abu-El-Haija, Maisam, Husain, Sohail Z, Barth, Bradley, Bellin, Melena, Fishman, Douglas S, Freedman, Steven D, Gariepy, Cheryl E, Giefer, Matthew J, Gonska, Tanja, Heyman, Melvin B, Himes, Ryan, Lin, Tom K, Maqbool, Asim, Mascarenhas, Maria, McFerron, Brian A, Morinville, Veronique D, Nathan, Jaimie D, Ooi, Chee Y, Perito, Emily R, Pohl, John F, Rhee, Sue, Schwarzenberg, Sarah J, Shah, Uzma, Troendle, David, Werlin, Steven L, Wilschanski, Michael, Zimmerman, M Bridget, Lowe, Mark E, Uc, Aliye, Liu, Quin Y, Liu, Quin Y, Abu-El-Haija, Maisam, Husain, Sohail Z, Barth, Bradley, Bellin, Melena, Fishman, Douglas S, Freedman, Steven D, Gariepy, Cheryl E, Giefer, Matthew J, Gonska, Tanja, Heyman, Melvin B, Himes, Ryan, Lin, Tom K, Maqbool, Asim, Mascarenhas, Maria, McFerron, Brian A, Morinville, Veronique D, Nathan, Jaimie D, Ooi, Chee Y, Perito, Emily R, Pohl, John F, Rhee, Sue, Schwarzenberg, Sarah J, Shah, Uzma, Troendle, David, Werlin, Steven L, Wilschanski, Michael, Zimmerman, M Bridget, Lowe, Mark E, and Uc, Aliye

Abstract

ObjectiveThe aim of the study was to determine the rate of progression from acute recurrent pancreatitis (ARP) to chronic pancreatitis (CP) in children and assess risk factors.Study designData were collected from the INternational Study group of Pediatric Pancreatitis: In search for a cuRE (INSPPIRE) cohort. Kaplan-Meier curves were constructed to calculate duration of progression from initial attack of acute pancreatitis (AP) to CP. Log-rank test was used to compare survival (nonprogression) probability distribution between groups. Cox proportional hazard regression models were fitted to obtain hazard ratio (with 95% confidence interval [CI]) of progression for each risk variable.ResultsOf 442 children, 251 had ARP and 191 had CP. The median time of progression from initial attack of AP to CP was 3.79 years. The progression was faster in those ages 6 years or older at the first episode of AP compared to those younger than 6 years (median time to CP: 2.91 vs 4.92 years; P = 0.01). Children with pathogenic PRSS1 variants progressed more rapidly to CP compared to children without PRSS1 variants (median time to CP: 2.52 vs 4.48 years; P = 0.003). Within 6 years after the initial AP attack, cumulative proportion with exocrine pancreatic insufficiency was 18.0% (95% CI: 12.4%, 25.6%); diabetes mellitus was 7.7% (95% CI: 4.2%, 14.1%).ConclusionsChildren with ARP rapidly progress to CP, exocrine pancreatic insufficiency, and diabetes. The progression to CP is faster in children who were 6 years or older at the first episode of AP or with pathogenic PRSS1 variants. The factors that affect the aggressive disease course in childhood warrant further investigation.

Published
2019

146. Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors.

Author

Schwarzenberg, Sarah J, Schwarzenberg, Sarah J, Uc, Aliye, Zimmerman, Bridget, Wilschanski, Michael, Wilcox, C Mel, Whitcomb, David C, Werlin, Steven L, Troendle, David, Tang, Gong, Slivka, Adam, Singh, Vikesh K, Sherman, Stuart, Shah, Uzma, Sandhu, Bimaljit S, Romagnuolo, Joseph, Rhee, Sue, Pohl, John F, Perito, Emily R, Ooi, Chee Y, Nathan, Jaimie D, Muniraj, Thiruvengadam, Morinville, Veronique D, McFerron, Brian, Mascarenhas, Maria, Maqbool, Asim, Liu, Quin, Lin, Tom K, Lewis, Michele, Husain, Sohail Z, Himes, Ryan, Heyman, Melvin B, Guda, Nalini, Gonska, Tanja, Giefer, Matthew J, Gelrud, Andres, Gariepy, Cheryl E, Gardner, Timothy B, Freedman, Steven D, Forsmark, Christopher E, Fishman, Douglas S, Cote, Gregory A, Conwell, Darwin, Brand, Randall E, Bellin, Melena, Barth, Bradley, Banks, Peter A, Anderson, Michelle A, Amann, Stephen T, Alkaade, Samer, Abu-El-Haija, Maisam, Abberbock, Judah N, Lowe, Mark E, Yadav, Dhiraj, Schwarzenberg, Sarah J, Schwarzenberg, Sarah J, Uc, Aliye, Zimmerman, Bridget, Wilschanski, Michael, Wilcox, C Mel, Whitcomb, David C, Werlin, Steven L, Troendle, David, Tang, Gong, Slivka, Adam, Singh, Vikesh K, Sherman, Stuart, Shah, Uzma, Sandhu, Bimaljit S, Romagnuolo, Joseph, Rhee, Sue, Pohl, John F, Perito, Emily R, Ooi, Chee Y, Nathan, Jaimie D, Muniraj, Thiruvengadam, Morinville, Veronique D, McFerron, Brian, Mascarenhas, Maria, Maqbool, Asim, Liu, Quin, Lin, Tom K, Lewis, Michele, Husain, Sohail Z, Himes, Ryan, Heyman, Melvin B, Guda, Nalini, Gonska, Tanja, Giefer, Matthew J, Gelrud, Andres, Gariepy, Cheryl E, Gardner, Timothy B, Freedman, Steven D, Forsmark, Christopher E, Fishman, Douglas S, Cote, Gregory A, Conwell, Darwin, Brand, Randall E, Bellin, Melena, Barth, Bradley, Banks, Peter A, Anderson, Michelle A, Amann, Stephen T, Alkaade, Samer, Abu-El-Haija, Maisam, Abberbock, Judah N, Lowe, Mark E, and Yadav, Dhiraj

Abstract

ObjectivesThe aim of the present study was to investigate the natural history of chronic pancreatitis (CP); patients in the North American Pancreatitis Study2 (NAPS2, adults) and INternational Study group of Pediatric Pancreatitis: In search for a cuRE (INSPPIRE, pediatric) were compared.MethodsDemographics, risk factors, disease duration, management and outcomes of 224 children and 1063 adults were compared using appropriate statistical tests for categorical and continuous variables.ResultsAlcohol was a risk in 53% of adults and 1% of children (P < 0.0001); tobacco in 50% of adults and 7% of children (P < 0.0001). Obstructive factors were more common in children (29% vs 19% in adults, P = 0.001). Genetic risk factors were found more often in children. Exocrine pancreatic insufficiency was similar (children 26% vs adult 33%, P = 0.107). Diabetes was more common in adults than children (36% vs 4% respectively, P < 0.0001). Median emergency room visits, hospitalizations, and missed days of work/school were similar across the cohorts. As a secondary analysis, NAPS2 subjects with childhood onset (NAPS2-CO) were compared with INSPPIRE subjects. These 2 cohorts were more similar than the total INSPPIRE and NAPS2 cohorts, including for genetic risk factors. The only risk factor significantly more common in the NAPS2-CO cohort compared with the INSPPIRE cohort was alcohol (9% NAPS2-CO vs 1% INSPPIRE cohorts, P = 0.011).ConclusionsDespite disparity in age of onset, children and adults with CP exhibit similarity in demographics, CP treatment, and pain. Differences between groups in radiographic findings and diabetes prevalence may be related to differences in risk factors associated with disease and length of time of CP.

Published
2019

147. An experimental method for evaluating constitutive models of myocardium in in vivo hearts

Author

Creswell, Lawrence L., Moulton, Michael J., Wyers, Stephan G., Pirolo, John S., Fishman, Douglas S., Perman, William H., Myers, Kent W., Actis, Ricardo L., Vannier, Michael W., Szabo, Barna A., and Pasque, Michael K.

Subjects
Heart muscle -- Models, Finite element method -- Observations, Biological sciences
Abstract

An experimental method that integrates interactive two-dimensional nonlinear finite element analysis with magnetic resonance radiofrequency tissue-tagging methods facilitates studies of constitutive models of myocardium in in vivo hearts. The method provides a new basis for analyzing 3-D constitutive models of the myocardium, including characteristics such as nonlinear behavior, anisotropy and regional inhomogeneity.

Published
1994

148. Health-Related Quality of Life in Pediatric Acute Recurrent or Chronic Pancreatitis: Association With Biopsychosocial Risk Factors

Author

Tham, See Wan, Wang, Fuchenchu, Gariepy, Cheryl E., Cress, Gretchen A., Abu-El-Haija, Maisam A., Bellin, Melena D., Ellery, Kate M., Fishman, Douglas S., Gonska, Tanja, Heyman, Melvin B., Lin, Tom K., Maqbool, Asim, McFerron, Brian A., Morinville, Veronique D., Nathan, Jaimie D., Ooi, Chee Y., Perito, Emily R., Schwarzenberg, Sarah Jane, Sellers, Zachary M., Shah, Uzma, Troendle, David M., Wilschanski, Michael, Zheng, Yuhua, Yuan, Ying, Lowe, Mark E., Uc, Aliye, and Palermo, Tonya M.

Published
2022
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149. Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopists and Endoscopists in Training: A Joint NASPGHAN/ESPGHAN Guideline

Author

Walsh, Catharine M., Lightdale, Jenifer R., Leibowitz, Ian H., Lerner, Diana G., Liu, Quin Y., Mack, David R., Mamula, Petar, Narula, Priya, Oliva, Salvatore, Riley, Matthew R., Rosh, Joel R., Tavares, Marta, Utterson, Elizabeth C., Amil-Dias, Jorge, Bontems, Patrick, Brill, Herbert, Croft, Nicholas M., Fishman, Douglas S., Furlano, Raoul I., Gillett, Peter M., Hojsak, Iva, Homan, Matjaž, Huynh, Hien Q., Jacobson, Kevan, Ambartsumyan, Lusine, Otley, Anthony R., Kramer, Robert E., McCreath, Graham A., Connan, Veronik, and Thomson, Mike A.

Published
2022
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150. Pediatric Endoscopy Quality Improvement Network Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline

Author

Walsh, Catharine M., Lightdale, Jenifer R., Fishman, Douglas S., Furlano, Raoul I., Mamula, Petar, Gillett, Peter M., Narula, Priya, Hojsak, Iva, Oliva, Salvatore, Homan, Matjaž, Riley, Matthew R., Huynh, Hien Q., Rosh, Joel R., Jacobson, Kevan, Tavares, Marta, Leibowitz, Ian H., Utterson, Elizabeth C., Croft, Nicholas M., Mack, David R., Brill, Herbert, Liu, Quin Y., Bontems, Patrick, Lerner, Diana G., Amil-Dias, Jorge, Kramer, Robert E., Otley, Anthony R., Ambartsumyan, Lusine, Connan, Veronik, McCreath, Graham A., and Thomson, Mike A.

Published
2022
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