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The pupae of Amphiops were often observed attached horizontally to twigs or floating objects. In the present paper, the author reports a case of pupa adheraena in A. mater Sharp, 1873, which was hanging under a plastic cover under artificial conditions. Furthermore, the potential morphological adaptations for the floating behavior in Amphiops pupae are discussed.

The Oriental pselaphine genus Horniella Raffray, 1905 currently contains 29 species. In this paper, six new species are described: H. nantouensis Zhang, Hu & Yin, sp. nov. and H. taiwanensis Zhang, Hu & Yin, sp. nov. from Taiwan, China; H. bifurca Zhang & Yin, sp. nov. and H. haucki Zhang & Yin, sp. nov. from Thailand; H. khasiensis Zhang & Yin, sp. nov. from northern India; and H. sabahensis Zhang & Yin, sp. nov. from eastern Malaysia. In addition, H. aculeata Yin & Li, 2015, originally described from Yunnan, China, is newly recorded from Thailand.

The final instar larva of Cephalaeschna risi Asahina, 1981 is described for the first time based on material from Taiwan. In Taiwan, the larva of C. risi can be separated from other aeshnid larvae by its relatively short antennae and presence of small protuberances on the legs. Diagnostic characters to distinguish it from other known larvae of Cephalaeschna are also discussed. A comprehensive description, detailed illustrations, bionomics and observations of the semi-terrestrial lifestyle of C. risi are presented. Finally, a key to the genera of Aeshnidae in Taiwan is proposed.

The Antarctic continent has extreme natural environment and fragile ecosystem. Mosses are one of the dominant floras in the Antarctic continent. However, their genomic features and adaptation processes to extreme environments remain poorly understood. Here, we assembled the high-quality genome sequence of the Antarctic moss (Pohlia nutans) with 698.20 Mb and 22 chromosomes. We found that the high proportion of repeat sequences and a recent whole-genome duplication (WGD) contribute to the large size genome of P. nutans when compared to other bryophytes. The genome of P. nutans harbors the signatures of massive segmental gene duplications and large expansions of gene families, likely facilitating neofunctionalization. Genomic characteristics that may support the Antarctic lifestyle of this moss comprise expanded gene families involved in phenylpropanoid biosynthesis, unsaturated fatty acid biosynthesis, and plant hormone signal transduction. Additional contributions include the significant expansion and upregulation of several genes encoding DNA photolyase, antioxidant enzymes, flavonoid biosynthesis enzymes, possibly reflecting diverse adaptive strategies. Notably, integrated multi-omic analyses elucidate flavonoid biosynthesis may function as the reactive oxygen species detoxification under UV-B radiation. Our studies provide insight into the unique features of the Antarctic moss genome and their molecular responses to extreme terrestrial environments.

Objective To investigate the application of transposition flaps in the reconstruction of perianal skin defects after tumor resection. Methods From September 2018 to December 2019, 16 cases of perianal skin defects were repaired with unilateral or bilateral transposition flaps. The wound size before closure ranged from 4 cm × 8 cm to 7 cm × 10 cm. Fourteen patients achieved primary healing. Wound dehiscence occurred in one patient at the flap tip, whereas a slight infection occurred in another patient, which healed after a dressing change. During the follow-up period of 3–6 months, all patients were satisfied with the perianal area both aesthetically and functionally. Conclusion Transposition flaps are a promising option for the repair of perianal skin defects after tumor removal. Owing to the simplicity of the flap design, the wide popularity of this flap type among surgeons is anticipated.

This paper examines whether politics causes regime shifts in deviations from the optimal monetary policy in the United Kingdom. After using a dynamic stochastic general equilibrium model to construct the welfare‐maximizing policy rule and deviations from the optimal Taylor rule, we show that politics does indeed play an important role in explaining these deviations. In addition to politics, unemployment rates account for regime shifts in the Taylor rule deviations.

The water scavenger beetle genus Coelostoma Brullé, 1835 of Taiwan is reviewed based on freshly collected material and museum specimens. Seven species are recognized, of which one new species, Coelostoma (Lachnocoelostoma) taiwanense sp. nov., is described. Distributional data of C. fallaciosum Orchymont, 1936 and C. stultum (Walker, 1858) are summarized. Coelostoma phallicum Orchymont, 1940, C. wui Orchymont, 1940, C. vitalisi Orchymont, 1923 and C. bhutanicum Jayaswal, 1972 are reported for the first time from Taiwan. Coelostoma vagum Orchymont, 1940 is excluded from Taiwanese fauna pending the rediscovery of vouchers or newly collected specimens. A distribution map and key to Taiwanese species of the genus are provided.

Additional file 8: Table S3. The percentages of non-apoptotic cells in the different phases of the cell cycle. The data were calculated based on the results in the histograms indicating a representative cell cycle (Fig. 6).

Additional file 5: Fig. S5. Upregulation of CDK6 in MDR KB-C2 cells compared to KB-3-1 cells. Transcriptome sequencing and quantification were performed in the MDR KB-C2 cells and drug sensitive parental KB-3-1 cells in the same condition, and the data showing the level of all the cdk6 transcripts is summarized in this graph. As indicated by the transcripts per million mapped reads (TPM) value, the number of full-length-cdk6 transcripts (mRNA) in KB-C2 cells were 7-folds of that in KB-3-1 cells. The transcripts ENST00000265734 and ENST00000424848 corresponding to the full-length of CDK6 protein were indicated by *.

Supplemental material, sj-docx-3-tct-10.1177_15330338221139981 for BCL6-SPECC1L: A Novel Fusion Gene in Nasopharyngeal Carcinoma by Shuo-Gui Fang, Tian-Liang Xia, Jian-Chang Fu, Tong Li, Qian Zhong and Fei Han in Technology in Cancer Research & Treatment

Additional file 3: Fig. S3. Regulation of CDK6 on ABCB1-mediated MDR in H460/MX80. A RT-PCR certification of cdk6 or cdk4 gene knockout in H460/MX80 cells. The cells were transfected with the CRISPR/Cas9 all-in-one plasmid and stabilized for 2 weeks and then analyzed for the cdk4 or cdk6 mRNA amounts. B MTT analysis of cell viability of MDR H460/MX80 cells (with very low level of ABCB1 expression) and the cdk6-deficient H460/MX80 cells, i.e., H460/MX80-k.o.cdk6 cells. Paclitaxel and colchicine, which are ABCB1 substates, were used for co-culture with H460/MX80 and H460/MX80-k.o.cdk6 cells for 72 h.

Additional file 6: Table S1. Differential expression of CDK6, ABCB1, CDK4, PIK3CA, PIK3CB and GAPDH genes in KB-C2 and KB-C2-k.o.cdk6. Identical amounts of total RNA from KB-C2 and KB-C2-k.o.cdk6 cells were analyzed for transcriptome sequences and differential gene expression. The transcripts encoding full or effective length of proteins are listed.

Additional file 2: Fig. S2. Protein-protein interaction of the proteins which are most correlated with endocrine resistance.

Additional file 1: Fig. S1. Network and the interactions of the Top10 differentially expressed genes involved in KEGG Endocrine resistance. A Network of enriched terms colored by cluster ID, where nodes that share the same cluster ID are typically close to each other. B Protein-protein interaction network and components identified in the gene lists. String platform was used for the analysis.

Additional file 7: Table S2. Downregulation of the expression level of CDK6 in KB-C2-k.o.110α, KB-C2-k.o.110β, MX80-k.o.110α, or MX80-k.o.110β populations.

Additional file 4: Fig. S4. Upregulation of ABCB1 in MDR KB-C2 cells compared to KB-3-1 cells. Transcriptome sequencing and quantification were performed in the MDR KB-C2 cells and drug sensitive parental KB-3-1 cells in the same condition, and the data showing the level of all the ABCB1 transcripts is summarized in the graph. As indicated by the transcripts per million mapped reads (TPM) value, the number of full-length-ABCB1 transcripts (mRNA) in KB-C2 cells were substantially increased as compared with that in KB-3-1 cells. The transcripts ENST00000265724, ENST00000622132 and MSTRG.27385.1 corresponding to the full-length of ABCB1 protein were indicated by *.

Zoraptera shows extreme uniformity in general body morphology, with the exception of Formosozoros (=Zorotypus) newi Chao & Chen, 2000, which stands out in terms of the shape and arrangement of its legs, the cerci, and several other morphological characters. After critical evaluation, we found that this species is not a zorapteran but is instead a nymph (1st instar) of an earwig; i.e., F. newi is a dermapteran. Because of the lack of morphological descriptions of Dermaptera nymphs that would allow species identification, and because the type material of F. newi is lost, a more detailed classification is not possible. We therefore propose that the genus name Formosozoros Chao & Chen, 2000 and the species name Formosozoros newi Chao & Chen, 2000 are nomina dubia.

Hu, Fang-Shuo, Chen, Szu-Lung, Song, Rui-Bin, Yeh, Wen-Chi (2021): Variation in Fukienogomphus prometheus (Lieftinck, 1939) reveals Stylurus takashii (Asahina, 1966) as a junior synonym, with discussion on the status of F. choifongae Wilson & Tam, 2006 (Odonata: Gomphidae). Zootaxa 5072 (1): 23-33, DOI: https://doi.org/10.11646/zootaxa.5072.1.3

Fukienogomphus prometheus (Lieftinck, 1939) ���AE��ffi��������Oi��ffi (Figs 1���5, 7���11, 13���14) Gomphus prometheus, Lieftinck 1939: 278 Fukienogomphus prometheus, Chao 1954: 39 Gomphus takashii, Asahina 1966: 113, syn. nov. Asiagomphus takashii, Asahina 1985: 7 Stylurus takashii, Zhao 1990: 140 Materials examined. Holotype of S. takashii, ♀, NSMT; TAIWAN: JUN.20.1965, ������ffl [=Nanshanshi; blue words stamped on triangular envelope] / Gomphus takashii Asahina Holotype [hand writing black words on the triangular paper bag] / Holotypus [red rectangular label, print]. TAIWAN: Yilan County: 1 ♀, Fushan [AE���], Yuanshan Township, 28-IV-1995, leg. W.-C. Yeh (MSC); 2 ♂♂, ditto, 27-VI-1995, leg. W.-C. Yeh (MSC); 1 ♀, Shenme Lake [AE���ae], Nanao Township, 22-VIII-2005, leg. W.-C. Yeh (TFRI). New Taipei City: 1 ♂ & 1 ♀, Pingan [������], Xindian District, 10-V-1998, leg. W.-C. Yeh (TFRI); 1 ♂, ditto, 30-VI-2004, leg. W.-C. Yeh (TGC); 1 ♂, Guishan [M���], Xindian District, 02-V-2008, leg. W.-C. Yeh (TFRI); 1 ♀, ditto, 11-V-2008, leg. W.-C. Yeh (TFRI); 1 ♂, Tonghou [������], Wulai District, 31-V-2003, leg. W.-C. Yeh (TFRI); 1 ♂, ditto, 06-VI-2007, leg. W.- C. Yeh (KPMN); 1 ♂, Xikeng Forest Trail [OEnj���dz], Wulai District, 23-V-2012, leg. W.-C. Yeh (TFRI); 1 ♂, Manyueyuan [���������], Sanxia District, 15-VI-2008, leg. W.-C. Yeh (TFRI). Taipei City: 1 ♂, Neishuangxi [������ ffl], Shihlin District, 22-VI-2008, leg. W.-C. Yeh (TFRI). The body pattern of F. prometheus is variable within its range but more constant in Taiwanese specimens we have examined, either in specimens or the images of live insects. The two lateral black stripes of synthorax, the second and the third according to Zhao (1990), are usually distinct and entire in males (Fig. 1); the variation of this character seems sex-related, as the females exclusively have the second stripe broken at the middle for a distance around 1/3���1/2 length of the stripe, and the third stripe becomes narrower and indistinct toward the lower end (Figs 2 & 11). Other variations of body pattern in the Taiwanese F. prometheus include the paired spots on the labrum and the extent of antehumeral stripes. The paired yellow labral spots are usually absent (Fig. 3) but can be present in few specimens. The antehumeral stripes are usually vestigial, leaving only an upper spot and rarely also a lower short stripe (Figs 1 & 2); in few female specimens, a short lower stripe is present and sometimes even connected to the upper spot to form a short antehumeral stripe (Fig. 11). Considering the variations mentioned above, the body pattern of the holotype of S. takashii as shown here (Figs 4 & 7) does not differ from those found in the female Taiwanese F. prometheus. In morphology, the female F. prometheus is characterized mainly by a short spine locating on the outer-posterior corner of the lateral ocellus, in additional to a larger, low and obtuse tubercle on the inner-posterior corner (Fig. 3). Further, the female subgenital plate of F. prometheus is equilaterally triangular, with the length as long as 1/4 of the 9th abdominal segment; the plate is divided by a middle slit running from the apex to around basal 1/2 of the plate (Fig. 5). These morphological characters fit well also with those of the holotype of S. takashii mentioned by Asahina and examined by us (Figs 4 & 8). Distribution. China (Zhejiang, Fujian, Guangdong and Hainan); Taiwan (Taipei, New Taipei, Taoyuan, Keelung, Hsinchu, Miaoli and Nantou), Vietnam (Lieftinck et al. 1984; Kompier 2015; Zhang 2019; this study). The distributional map of F. prometheus in Taiwan is shown in Fig. 15. Ecology. The habitats of F. prometheus observed in northern Taiwan are mainly shaded creeks (Fig. 12) or tiny muddy trenches in well-forested areas. The females usually oviposit alone at the shallow margins of small pools in creeks, or in trenches fed by the water from nearby seepage. The territorial males often perch on undergrowth vegetation near the female oviposition sites, sometimes as low as 10 cm above the ground. In Guangdong, F. prometheus inhabits shady seepages, narrow creeks with slow-flow and marshes or pools with thick bottom silt. In Pingan and Tonghou where the oviposition sites are semi-shaded tiny trenches, the ovipositing behaviors of females were stealth and difficult to discover, usually undertook under the coverage of dense weeds growing along the banks of trenches. The females perform egg-gathering behaviors before each dipping to release the eggs, either by hovering still low in the air above the water or sitting on vegetation adjacent to the dipping site. The larvae dwell on muddy seepages with weedy vegetation or amongst the detritus accumulated at the bottom of tiny trenches or pools in creeks. In Taiwan, F. prometheus is confined in low mountainous areas in the north, ranging from 40���1100 m.a.s.l. in elevation; the only exceptional record is the type locality of S. takashii in Nanshanshi where it is located in Nantou County in central Taiwan (Fig. 15)., Published as part of Hu, Fang-Shuo, Chen, Szu-Lung, Song, Rui-Bin & Yeh, Wen-Chi, 2021, Variation in Fukienogomphus prometheus (Lieftinck, 1939) reveals Stylurus takashii (Asahina, 1966) as a junior synonym, with discussion on the status of F. choifongae Wilson & Tam, 2006 (Odonata: Gomphidae), pp. 23-33 in Zootaxa 5072 (1) on pages 24-27, DOI: 10.11646/zootaxa.5072.1.3, http://zenodo.org/record/5728943, {"references":["Lieftinck, M. A. (1939) Six new species of Gomphus from China. Temminckia, 4, 277 - 297.","Asahina, S. (1966) Taiwanese Odonata taken by 1965 field works. Kontyu, 34 (1), 105 - 121.","Asahina, S. (1985) A revisional study of Japanese and East Asiatic \" Gomphus \" species with the description of Asiagomphus gen. nov. Gekkan-Mushi, 169, 6 - 17. [in Japanese]","Zhao, H. - F. (1990) The gomphid dragonflies of China (Odonata: Gomphidae). The Science and Technology Publishing House, Fuzhou, 486 pp.","Lieftinck, M. A., Lien, J. - C. & Maa, T. - C. (1984) Catalogue of Taiwanese dragonflies (Insecta: Odonata). Asian Ecological Society, Taichung, 81 pp.","Kompier, T. (2015) Fukienogomphus prometheus - new for Vietnam! The website Dragonflies and damselflies in Vietnam. Available from: http: // odonatavietnam. blogspot. com / 2015 / 04 / fukienogomphus-prometheus-new-for. html (accessed 8 August 2021)","Zhang, H. - M. (2019) Dragonflies and damselflies of China. Vol. 1. Chongqing University Press, Chongqing, 736 pp."]}