124 results on '"Elliott, John O."'
Search Results
102. Pharmacist Survey
- Author
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McAuley, James W., primary, Chen, Alyssa Y., additional, Elliott, John O., additional, and Shneker, Bassel F., additional
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- 2009
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103. Modeling epilepsy disparities among ethnic groups in Philadelphia, PA
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Wheeler, David C., primary, Waller, Lance A., additional, and Elliott, John O., additional
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- 2008
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104. Examining Gender with General Creativity and Preferences for Creative Persons in College Students within the Sciences and the Arts
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CHARYTON, CHRISTINE, primary, BASHAM, KIMBERLY M., additional, and ELLIOTT, JOHN O., additional
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- 2008
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105. The "Billion Dollar Box" Study of Science Missions to Saturnian Satellites
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Spilker, Thomas R., primary, Reh, Kim R., additional, Elliott, John O., additional, Lorenz, Ralph, additional, and Spencer, John, additional
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- 2008
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106. Pseudoseizure Questionnaire
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Shneker, Bassel F., primary and Elliott, John O., additional
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- 2008
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107. Concept for Titan Exploration Using a Radioisotopically Heated Montgolfiere
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Elliott, John O., primary, Reh, Kim, additional, and Spilker, Tom, additional
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- 2007
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108. Titan Exploration Using a Radioisotopically-Heated Montgolfiere Balloon
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Elliott, John O., primary, Reh, Kim, additional, and Spilker, Tom, additional
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- 2007
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109. Lunar Fission Surface Power System Design and Implementation Concept
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Elliott, John O., primary
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- 2006
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110. Mission Concept for a Nuclear Reactor-Powered Mars Cryobot Lander
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Elliott, John O., primary
- Published
- 2003
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111. Radiation Shielding Design and Orientation Considerations for a 1 kWe Heat Pipe Cooled Reactor Utilized to Bore Through the Ice Caps of Mars.
- Author
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Fensin, Michael L., Elliott, John O., Lipinski, Ronald J., and Poston, David I.
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HEAT pipes , *HEAT transfer , *ICE caps , *SNOW , *RADIATION shielding , *MARS (Planet) - Abstract
The goal in designing any space power system is to develop a system able to meet the mission requirements for success while minimizing the overall costs. The mission requirements for the this study was to develop a reactor (with Stirling engine power conversion) and shielding configuration able to fit, along with all the other necessary science equipment, in a Cryobot 3 m high with ∼0.5 m diameter hull, produce 1 kWe for 5yrs, and not adversely affect the mission science by keeping the total integrated dose to the science equipment below 150 krad. Since in most space power missions the overall system mass dictates the mission cost, the shielding designs in this study incorporated Martian water extracted at the startup site in order to minimize the tungsten and LiH mass loading at launch. Different reliability and mass minimization concerns led to three design configuration evolutions. With the help of implementing Martian water and configuring the reactor as far from the science equipment as possible, the needed tungsten and LiH shield mass was minimized. This study further characterizes the startup dose and the necessary mission requirements in order to ensure integrity of the surface equipment during reactor startup phase. © 2006 American Institute of Physics [ABSTRACT FROM AUTHOR]
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- 2006
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112. Concept for a Radioisotope Powered Dual Mode Lunar Rover.
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Elliott, John O., Schriener, Timothy M., and Coste, Keith
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LUNAR surface vehicles , *ROVING vehicles (Astronautics) , *RADIOISOTOPES , *NUCLEAR engineering , *RADIOACTIVE substances , *SPACE exploration , *ASTRONAUTICS - Abstract
Over three decades ago, the Apollo missions manifestly demonstrated the value of a lunar rover to expand the exploration activities of lunar astronauts. The stated plan of the new Vision for Space Exploration to establish a permanent presence on the moon in the next decades gives new impetus to providing long range roving and exploration capability in support of the siting, construction, and maintenance of future human bases. The incorporation of radioisotope power systems and telerobotic capability in the design has the potential to significantly expand the capability of such a rover, allowing continuous operation during the full lunar day/night cycle, as well as enabling exploration in permanently shadowed regions that may be of interest to humans for the resources they may hold. This paper describes a concept that builds on earlier studies originated in the Apollo program for a Dual Mode (crewed and telerobotic) Lunar Roving Vehicle (DMLRV). The goal of this vehicle would be to provide a multipurpose infrastructure element and remote science platform for the exploration of the moon. The DMLRV would be essential for extending the productivity of human exploration crews, and would provide a unique capability for diverse long-range, long-duration science exploration between human visits. With minimal reconfiguration this vehicle could also provide the basic platform to support a range of site survey and preparation activities in anticipation of the establishment of a permanent human presence on the moon. A conceptual design is presented for the DMLRV, including discussion of mission architecture, vehicle performance, representative science payload accommodation, and equipment and crew radiation considerations. © 2006 American Institute of Physics [ABSTRACT FROM AUTHOR]
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- 2006
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113. NEPTranS; A Shuttle-Tended NEP Interplanetary Transportation System.
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Elliott, John O., Nakagawa, Roy Y., Spilker, Thomas R., Lipinski, Ronald J., Poston, David I., and Moreland, Dean W.
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SPACE vehicles , *INTERPLANETARY voyages - Abstract
Recently, a study was performed by a team from JPL and the DOE to develop a mission architecture for a reusable NEP Interplanetary Transfer Vehicle, a “Space Truck”. This vehicle is designed to be used for delivery of payloads from Earth to a variety of destinations, including Mars and Venus, dependent on mission needs. In addition to delivering payloads to the target bodies, the vehicle is designed to perform autonomous rendezvous and capture of sample return capsules at the destination for return to Earth. In order to maximize the utility of the vehicle, its design is optimized for servicing between missions with the Space Shuttle. Fuel tanks, ion thrusters, and Power Management and Distribution electronics are all on-orbit replaceable units, located at the payload interface end of the spacecraft to ensure a minimal radiation dose to the Shuttle and crew during maintenance and resupply operations. Operational flexibility is maximized through the use of replaceable fuel tanks and thrusters, allowing tailoring of fuel load to any given destination and payload mass. This paper discusses the preliminary design developed for the NEP Interplanetary Transfer Vehicle, including its configuration and design features, and outlines the concept for mission design, including discussion of unique requirements for launch, deployment and operations with the Space Shuttle, and rendezvous and servicing by the Shuttle in Earth orbit following a return from each target destination. © 2003 American Institute of Physics [ABSTRACT FROM AUTHOR]
- Published
- 2003
114. Design Concept for a Nuclear Reactor-Powered Mars Rover.
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Elliott, John O., Lipinski, Ronald J., and Poston, David I.
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PROJECT Rover , *MARS (Planet) , *NUCLEAR reactors - Abstract
A study was recently carried out by a team from JPL and the DOE to investigate the utility of a DOE-developed 3 kWe surface fission power system for Mars missions. The team was originally tasked to perform a study to evaluate the usefulness and feasibility of incorporation of such a power system into a landed mission. In the course of the study it became clear that the application of such a power system was enabling to a wide variety of potential missions. Of these, two missions were developed, one for a stationary lander and one for a reactor-powered rover. This paper discusses the design of the rover mission, which was developed around the concept of incorporating the fission power system directly into a large rover chassis to provide high power, long range traverse capability. The rover design is based on a minimum extrapolation of technology, and adapts existing concepts developed at JPL for the 2009 Mars Science Laboratory (MSL) rover, lander and EDL systems. The small size of the reactor allowed its incorporation directly into an existing large MSL rover chassis design, allowing direct use of MSL aeroshell and pallet lander elements, beefed up to support the significantly greater mass involved in the nuclear power system and its associated shielding. This paper describes the unique design challenges encountered in the development of this mission architecture and incorporation of the fission power system in the rover, and presents a detailed description of the final design of this innovative concept for providing long range, long duration mobility on Mars. © 2003 American Institute of Physics [ABSTRACT FROM AUTHOR]
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- 2003
115. The impact of art therapy on anxiety and hope in patients with gynecologic cancer undergoing chemotherapy.
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Bell, Jeffrey G., McHale, Jennifer, Elliott, John O., and Heaton, Wendy
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ART therapy , *EXPRESSIVE arts therapy , *GYNECOLOGIC cancer , *CANCER chemotherapy , *CANCER patients , *DRAMA therapy - Abstract
Clinical research investigating the benefits of art therapy in individuals undergoing cancer treatment is growing, yet study designs focusing on certain cancers such as gynecologic malignancies are lacking. This study aimed to assess the impact of art therapy interventions on both anxiety and hope in patients with gynecologic cancer patients. The study design was prospective and non-randomized. Eligible patients had a primary or recurrent gynecologic malignancy, and were scheduled to receive at least six cycles of chemotherapy over eighteen weeks. Patients completed State Hope and State Anxiety questionnaires before and after each of five art therapy interventions during chemotherapy. Eighteen patients completed the study. Both anxiety and hope significantly improved after each art therapy session except for one. In addition, both anxiety and hope significantly improved between visit 1 and visit 5: State Hope -Visit 1 vs. Visit 5 (35.3 ± 7.8 vs. 40.0 ± 7.2), p = 0.019, effect size = 0.63; State Anxiety -Visit 1 vs. Visit 5 (32.8 ± 9.3 vs. 27.8 ± 8.8), p = 0.038, effect size = −0.53. The results showed art-based interventions facilitated by a board-certified art therapist positively impacted two domains in the quality of life of gynecologic cancer patients undergoing chemotherapy. The attitude of patients, namely, a willingness to accept art therapy, may influence the outcome of the interventions. • The study examined the efficacy of art therapy on decreasing anxiety and improving hope. • Limited research exits using art therapy with women diagnosed with gynecological cancers. • Art therapy interventions significantly decreased anxiety in each of the five sessions. • Feelings of hope improved after four out of the five art therapy sessions. • Results indicated that patients benefit from art therapy while receiving chemotherapy treatment. [ABSTRACT FROM AUTHOR]
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- 2022
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116. The effect of art therapy on the quality of life in patients with a gynecologic cancer receiving chemotherapy.
- Author
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Wiswell, Sara, Bell, Jeffrey G., McHale, Jennifer, Elliott, John O., Rath, Kellie, and Clements, Aine
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ART therapy , *GYNECOLOGIC cancer , *FUNCTIONAL assessment , *CANCER chemotherapy , *CANCER patients - Abstract
Abstract Objectives Most art therapy research has involved patients with malignancies other than gynecologic cancer. The current study aimed to assess the impact of an art therapy intervention on the quality of life (QOL) in patients with gynecologic cancer who were receiving chemotherapy. Methods This was a prospective, non-randomized, pilot study. Eligible patients had a primary or recurrent gynecologic malignancy scheduled to be treated with at least 6 cycles of chemotherapy over 18 weeks. The intervention consisted of five sessions of art therapy during the chemotherapy. Patients completed a Functional Assessment of Cancer Therapy-General (FACT-G) questionnaire prior to starting chemotherapy, and again at completion of the fifth session. Differences between the FACT-G scores were examined by paired t -tests. An increase in the mean FACT-G score indicated an improvement in QOL. At each session, the patients completed a separate, supplemental questionnaire to subjectively rate the benefit of the session and to express their experience with the art intervention. Results Twenty-four patients enrolled. Eight did not complete the study, leaving 16 evaluable patients. The mean FACT-G score pre-chemotherapy was 82.3 (95% CI: 75.5, 89.2), and post-art therapy was 78.6 (95% CI: 71.7, 85.5). The mean change in QOL was −3.7 points (95% CI: −10.7, 3.2, p = 0.270). A supplemental questionnaire indicated that 15 of 16 patients felt that art therapy was beneficial at each session. Conclusions FACT-G scores did not significantly change over the course of chemotherapy in patients with gynecologic cancers receiving art therapy. Several published studies have indicated that chemotherapy is associated with a decline in QOL. Our results suggest art therapy may help to prevent or mitigate this decline. Highlights • Pre and post-QOL data (FACT-G) were collected on 16 patients receiving art therapy during chemotherapy treatment. • We found a non-significant mean change in QOL of −3.7 points (95% CI: −10.7, 3.2, p = 0.270). • Art therapy may help to prevent the typical decline in QOL during treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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117. Documentation of International Classification of Headache Disorders Criteria in Patient Medical Records: A Retrospective Cohort Analysis.
- Author
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Pershing M, Hirekhan O, Syed A, Elliott JO, and Toot J
- Abstract
Objective: To determine headache diagnosis and treatment patterns in the outpatient setting, focusing on documentation of the International Classification of Headache Disorders (ICHD) criteria., Design, Setting, and Participants: Retrospective cohort data were collected from electronic medical records of adults aged 18-35 who presented to resident-staffed family medicine outpatient clinics in the Midwest, USA, for a new or worsening headache between 2015 and 2016. Diagnosis codes were used to summarize the overall nature and prevalence of headaches. A random subset of 30 patients each for migraine headache (MGH) with and without aura and tension-type headache (TTH) were reviewed to determine how many of the five possible ICHD criteria were documented. Demographics/clinical characteristics, ICHD criteria, number and type of medications, and healthcare utilization (imaging, primary and emergency department care) through one year following the initial visit were summarized and compared across headache types., Results: There were 716 unique patients during the study period (414 MGH, 227 unspecified headaches, 75 TTH, or others). Complete ICHD criteria were documented for two patients in total. There was partial documentation (e.g., one to four of the possible five) for 30% of TTH, 63% of MGH without aura, and 77% of MGH with aura (p<0.05). Across headache types, patients were prescribed an average of 2.3 to 3.3 medications over one year, with MGH patients generally trying more medications (up to eight for those with aura and up to 12 for those without). Abortive or rescue medications were prescribed to nearly all patients; prophylactics were prescribed for 50% of MGH with aura, 66.7% of MGH without aura, and 53.3%. Non-pharmacologic interventions were less prescribed: 33.3% of TTH patients and 3.3% of MGH types combined (p<0.05). Healthcare utilization was highest for MGH with aura (ED visits) and without aura (clinic visits) patients compared to TTH (p<0.001)., Conclusion: Headache-related documentation is often incomplete, which may limit interpretation and associations between diagnoses, prescribing patterns, and healthcare utilization. Future studies should evaluate the use of electronic medical records (EMR)-based templates to improve documentation, and additional detailed studies are needed in the local setting to determine whether treatment, including the use of non-pharmacologic and prophylactic methods of treatment, is optimal., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Pershing et al.)
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- 2024
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118. Use of Low-Cost Task Trainer for Emergency Department Thoracotomy Training in General Surgery Residency Program.
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Misra A, Chapman A, Watson WD, Bach JA, Bonta MJ, Elliott JO, and Dominguez EP
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- Humans, Thoracotomy education, Pilot Projects, Prospective Studies, Emergency Service, Hospital, Clinical Competence, Internship and Residency, General Surgery education
- Abstract
Objective: Emergency department thoracotomy (EDT) is an uncommon but potentially lifesaving procedure that warrants familiarity with anatomy, instruments, and indications necessary for completion. To address this need, we developed a low-cost EDT trainer. The primary objective of this study was to compare the effectiveness of a low-cost EDT trainer to teach emergency department thoracotomy with a discussion-based teaching session. Secondary objective was to study the face validity of the low-cost EDT trainer., Design: A prospective 2-phase randomized control study was conducted. Participants were randomly divided into two groups. In phase one, baseline medical knowledge for both groups was assessed using a multiple-choice question pretest. In Group 1, each participant was taught EDT using a one-on-one discussion with a trauma surgeon, whereas Group 2 used the EDT trainer and debriefing for training. In phase 2 (1 month later), all participants completed a knowledge retention test and performed a videoed EDT using our EDT trainer, the video recordings were later reviewed by content experts blinded to the study participants using a checklist with a maximum score of 22. The participants also completed a reaction survey at the end of phase 2 of the study., Setting: OhioHealth Riverside Methodist Hospital, an urban tertiary care academic hospital in Columbus, Ohio., Participants: Nine senior surgery residents from training years 3 to 5., Results: The mean score for the performance of the procedure for the simulation-based (Group 2) was significantly higher than that of the discussion-based (Group 1) (Rater 1: 21.2 ± 0.8 vs. 19.0 ± 2.0, p = 0.05, Rater 2: 20.4 ± 1.5 vs. 18.3±1.0, p = 0.04). Group 2 also was quicker than Group 1 in deciding to start the procedure by approximately 56 seconds. When comparing the mean pretest knowledge score to the mean knowledge retention score 30 days after training, the discussion-based group improved from 58.33% to 81.25% (p = 0.01); the simulation-trained group's scores remained at 68.33%. All the participants agreed or strongly agreed that the simulator provided a realistic opportunity to perform EDT and improved their confidence., Conclusions: The results of this pilot study support our hypothesis that using a low-cost EDT trainer effectively improves general surgery residents' confidence and procedural skills scores in a simulated environment. Further training with low-cost simulators may provide surgical residents with deliberate practice opportunities and improve performance when learning low-frequency procedures., (Copyright © 2023 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.)
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- 2024
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119. Plastic Surgery Tourism: Complications, Costs, and Unnecessary Spending?
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Hery D, Schwarte B, Patel K, Elliott JO, and Vasko S
- Abstract
Background: The liability of plastic surgery tourism in patient health and postoperative resource allocation is significant. Procedures completed within the context of medical tourism often lack rigorous quality assurance and provide limited preoperative evaluation or postoperative care. Not only does this jeopardize the patient's well-being, but it also increases the financial burden and redirects invaluable resources domestically through often unnecessary diagnostic tests and hospitalizations., Objectives: This manuscript will examine the complications and associated costs following plastic surgery tourism and highlight unnecessary expenses for patients with outpatient complications., Methods: A retrospective review was conducted of all patients 18 years or older who underwent destination surgery and were seen within 1 year postoperatively in consultation with plastic surgery at our health system between January 11, 2015 and January 7, 2022. Patient admissions were reviewed and deemed necessary or unnecessary after review by 2 physicians., Results: The inclusion criteria were met by 41 patients, of whom hospitalization was deemed necessary in 28 patients vs unnecessary in 13 patients. The most common procedures included abdominoplasty, liposuction, breast augmentation, and "Brazilian butt lift." The most common complications were seroma and infection. Patients deemed to have a necessary admission often required at least 1 operation, were more likely to need intravenous antibiotics, were less likely to have the diagnosis of "pain," necessitated a longer hospitalization, and incurred a higher cost. The total financial burden was $523,272 for all 41 patients., Conclusions: Plastic surgery tourism poses substantial health risks, the morbidities are expensive, and it strains hospital resources., (© The Author(s) 2023. Published by Oxford University Press on behalf of The Aesthetic Society.)
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- 2023
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120. Factors Associated With No-Show to Ambulatory Tele-Video Neurology Visits.
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Gudlavalleti ASV, Elliott JO, and Asadi R
- Abstract
Introduction Telehealth visits (TH) have become an important pillar of healthcare delivery during the COVID pandemic. No-shows (NS) may result in delays in clinical care and in lost revenue. Understanding the factors associated with NS may help providers take measures to decrease the frequency and impact of NS in their clinics. We aim to study the demographic and clinical diagnoses associated with NS to ambulatory telehealth neurology visits. Methods We conducted a retrospective chart review of all telehealth video visits (THV) in our healthcare system from 1/1/2021 to 5/1/2021 (cross-sectional study). All patients at or above 18 years of age who either had a completed visit (CV) or had an NS for their neurology ambulatory THV were included. Patients having missing demographic variables and not meeting the ICD-10 primary diagnosis codes were excluded. Demographic factors and ICD-10 primary diagnosis codes were retrieved. NS and CV groups were compared using independent samples t-tests and chi-square tests as appropriate. Multivariate regression, with backward elimination, was conducted to identify pertinent variables. Results Our search resulted in 4,670 unique THV encounters out of which 428 (9.2%) were NS and 4,242 (90.8%) were CV. Multivariate regression with backward elimination showed that the odds of NS were higher with a self-identified non-Caucasian race OR = 1.65 (95%, CI: 1.28-2.14), possessing Medicaid insurance OR = 1.81 (95%, CI: 1.54-2.12) and with primary diagnoses of sleep disorders OR = 10.87 (95%, CI: 5.55-39.84), gait abnormalities (OR = 3.63 (95%, CI: 1.81-7.27), and back/radicular pain OR = 5.62 (95%, CI: 2.84-11.10). Being married was associated with CVs OR = 0.74 (95%, CI: 0.59-0.91) as well as primary diagnoses of multiple sclerosis OR = 0.24 (95%, CI: 0.13-0.44) and movement disorders OR = 0.41 (95%, CI: 0.25-0.68). Conclusion Demographic factors, such as self-identified race, insurance status, and primary neurological diagnosis codes, can be helpful to predict an NS to neurology THs. This data can be used to warn providers regarding the risk of NS., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Gudlavalleti et al.)
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- 2023
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121. Cervical cancer radiation therapy compliance rates based on location of radiation therapy.
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Calo C, Elliott JO, Clements A, Reid G, and Rath K
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- Brachytherapy, Female, Humans, Middle Aged, Retrospective Studies, Health Services Accessibility, Patient Compliance, Uterine Cervical Neoplasms radiotherapy
- Abstract
Objective: Completion of radiation therapy (RT) within 60 days has been proposed as a national quality measure for patients with carcinoma of the cervix as protracted RT has been associated with worse oncologic outcomes. The objective of this study was to compare compliance rates based on location of RT administration., Methods: This was a retrospective chart review of patients diagnosed with cervical cancer between January of 2000 to December of 2016 who were planned to undergo primary treatment with sensitizing chemotherapy and RT. Patients who completed both external beam radiation therapy (EBRT) and brachytherapy (BT) at the primary institution were compared to patients who completed a portion or all of their RT elsewhere. The primary outcome measured was completion of RT within 60 days. Secondary outcomes included compliance with sensitizing chemotherapy, total radiation dose, recurrence rate, progression free survival (PFS) and overall survival (OS). The groups were compared using standard statistical analysis., Results: This study included 100 patients, 75 of which received all of their RT at the primary institution. These patients were more likely to complete RT within 60 days when compared to patients who underwent RT at different facilities (58.7% vs 24%, respectively; p = 0.005). Patients who underwent all of their RT at the primary institution completed their therapy an average of 16.4 days sooner (75.1 ± 21.3 days versus 58.7 ± 13.2 days; p = 0.001). Overall survival was significantly improved in this group (p = 0.03)., Conclusion: Women who complete EBRT and BT at different institutions are more likely to have a protracted RT course (>60 days). These patients should be identified at diagnosis and efforts made to coordinate their care to avoid delays in treatment., (Copyright © 2018 Elsevier Inc. All rights reserved.)
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- 2019
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122. Oral Ketorolac for Pain Relief During Intrauterine Device Insertion: A Double-Blinded Randomized Controlled Trial.
- Author
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Crawford M, Davy S, Book N, Elliott JO, and Arora A
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- Adult, Double-Blind Method, Female, Humans, Young Adult, Anti-Inflammatory Agents, Non-Steroidal administration & dosage, Intrauterine Devices, Ketorolac administration & dosage, Pain, Procedural prevention & control
- Abstract
Objective: To evaluate if oral ketorolac provides effective pain relief during placement of an IUD for contraception., Methods: We conducted a double-blinded randomized controlled trial in a community hospital in Columbus, Ohio. Participants that met eligibility criteria were consented and randomized to receive either oral ketorolac 20 mg or placebo 40 to 60 minutes before IUD placement. Both participants and providers were blinded to the randomization group. The primary outcome was pain reduction (measured on a 0-10 numerical rating scale) during IUD placement. Data was analyzed using a two-sided independent samples t-test. An a priori sample size was calculated to detect a clinically meaningful difference of 2 points with 80% power. The type I error probability was α = 0.05., Results: Seventy-two participants were enrolled and randomized between May 2014 until March 2016. Thirty-five in the ketorolac group and 36 in the placebo group were analyzed. There were no differences in baseline characteristics between participants or providers, as well as pain ratings prior to the procedure, at tenaculum placement, or at uterine sounding. There was a significant decrease in the pain of the ketorolac versus the placebo group rating at IUD deployment (4.2 vs. 5.7, P = 0.031), overall pain rating (3.6 vs. 4.9, P = 0.047), and pain 10 minutes after the procedure (1.1 vs, 2.5, P = 0.007)., Conclusion: Oral ketorolac given 40 to 60 minutes prior to IUD insertion is effective in reducing pain during IUD deployment, overall pain, and pain 10 minutes after IUD placement., (Copyright © 2017 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
- Published
- 2017
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123. Effect of Maternal Retroplacental Leiomyomas on Fetal Growth.
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Knight JC, Elliott JO, and Amburgey OL
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- Adult, Birth Weight, Female, Humans, Infant, Small for Gestational Age, Leiomyoma diagnostic imaging, Pregnancy, Pregnancy Complications, Neoplastic diagnostic imaging, Retrospective Studies, Ultrasonography, Prenatal, Uterine Neoplasms diagnostic imaging, Fetal Development, Leiomyoma epidemiology, Pregnancy Complications, Neoplastic epidemiology, Uterine Neoplasms epidemiology
- Abstract
Objective: To evaluate the association between retroplacental leiomyoma identified on second trimester ultrasound and fetal growth., Methods: We performed a retrospective study comparing the presence or absence of one or more retroplacental leiomyomas on birth weight in a cohort of women with singleton pregnancies undergoing second trimester fetal anatomic ultrasound at our institution between 2007 and 2012. The incidence of small for gestational age (SGA) infants was recorded. Secondary analysis evaluated the effect of number and size of retroplacental leiomyomas., Results: Birth weight in women with at least one retroplacental leiomyoma was 177 grams less than in women without leiomyomas (95% CI -295 to -95, P = 0.003). There was a non-significant trend towards a higher incidence of SGA in infants born to women with retroplacental leiomyoma compared with women without leiomyoma (OR 2.84; 95% CI 0.97 to 6.84, P = 0.057). Women with a retroplacental leiomyoma > 4 cm in mean diameter were more likely to deliver an SGA infant than women without leiomyomas (OR 2.84, 95% CI 1.01 to 8.01; P = 0.048). Multiple retroplacental leiomyomas did not have a greater effect on pregnancy outcomes than single leiomyomas., Conclusion: Infants born to women with one or more retroplacental leiomyomas had a lower mean birth weight than infants born to women without leiomyomas. In addition, retroplacental leiomyomas > 4 cm in mean diameter were associated with an increased risk of delivering an SGA infant., (Published by Elsevier Inc.)
- Published
- 2016
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124. Suicidality, depression screening, and antiepileptic drugs: reaction to the FDA alert.
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Janati A, Shneker BF, Cios JS, and Elliott JO
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- Adverse Drug Reaction Reporting Systems, Depression epidemiology, Epilepsy epidemiology, Humans, Incidence, United States, Anticonvulsants adverse effects, Depression chemically induced, Epilepsy drug therapy, Epilepsy psychology, Suicide, United States Food and Drug Administration
- Published
- 2009
- Full Text
- View/download PDF
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