2,919 results on '"Eastmond, A"'
Search Results
102. Inhibition of Human Topoisomerase II in Vitro by Bioactive Benzene Metabolites
- Author
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Frantz, Christopher E., Chen, Hongwei, and Eastmond, David A.
- Published
- 1996
- Full Text
- View/download PDF
103. Carbon partitioning in developing embryos of oilseed rape (Brassica napus L.)
- Author
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Eastmond, Peter J.
- Subjects
580 ,Seed development - Published
- 1998
104. Genome Wide Analysis of Fatty Acid Desaturation and Its Response to Temperature
- Author
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Menard, Guillaume N., Moreno, Jose Martin, Bryant, Fiona M., Munoz-Azcarate, Olaya, Kelly, Amélie A., Hassani-Pak, Keywan, Kurup, Smita, and Eastmond, Peter J.
- Published
- 2017
105. ACYL-ACYL CARRIER PROTEIN DESATURASE2 and 3 Are Responsible for Making Omega-7 Fatty Acids in the Arabidopsis Aleurone
- Author
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Bryant, Fiona M., Munoz-Azcarate, Olaya, Kelly, Amélie A., Beaudoin, Frédéric, Kurup, Smita, and Eastmond, Peter J.
- Published
- 2016
106. Impactos Sociales y Ambientales de la Palma de Aceite: Perspectiva de los Campesinos en Campeche, México
- Author
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Isaac-Márquez, Ricardo, Valladares, Jorge Luis Sandoval, Spencer, Amarella Eastmond, Arcipreste, María Esther Ayala, Aguilar, Marco Antonio Arteaga, Márquez, Angélica Patricia Isaac, and González, María Consuelo Sánchez
- Published
- 2016
107. Bio-Producing Bacterial Cellulose Filaments through Co-Designing with Biological Characteristics
- Author
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Baurley, Roberta Morrow, Miriam Ribul, Heather Eastmond, Alexandra Lanot, and Sharon
- Subjects
circularity ,bacterial cellulose ,co-design ,bio-manufacturing ,biomaterials ,bio-design - Abstract
The need for circular textiles has led to an interest in the production of biologically derived materials, generating new research into the bioproduction of textiles through design and interdisciplinary approaches. Bacterial cellulose has been produced directly from fermentation into sheets but not yet investigated in terms of producing filaments directly from fermentation. This leaves a wealth of material qualities unexplored. Further, by growing the material directly into filaments, production such as wet spinning are made redundant, thus reducing textile manufacturing steps. The aim of this study was to grow the bio-material, namely bacterial cellulose directly into a filament. This was achieved using a method of co-designing with the characteristics of biological materials. The method combines approaches of material-driven textile design and human-centred co-design to investigate co-designing with the characteristics of living materials for biological material production. The project is part of a wider exploration of bio-manufacturing textiles from waste. The practice-based approach brought together biological sciences and material design through a series of iterative experiments. This, in turn, resulted in designing with the inherent characteristics of bacterial cellulose, and by doing so filaments were designed to be fabricated directly from fermentation. In this investigation, creative exploration was encouraged within a biological laboratory space, showing how interdisciplinary collaboration can offer innovative alternative bioproduction routes for textile filament production.
- Published
- 2023
- Full Text
- View/download PDF
108. The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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Adamina, M, Ademuyiwa, A, Adisa, A, Bhangu, A, Bravo, A, Cunha, M, Emile, S, Ghosh, D, Glasbey, J, Harris, B, Keller, D, Lawday, S, Lederhuber, H, Leventoglu, S, Li, E, Modolo, M, Mittal, R, Mohan, H, Nepogodiev, D, Parreno-Sacdalan, M, Pata, F, Pockney, P, Rutegard, M, Smart, N, Varghese, C, Siaw-Acheampong, K, Benson, R, Bywater, E, Chaudhry, D, Dawson, B, Evans, J, Gujjuri, R, Heritage, E, Jones, C, Kamarajah, S, Khatri, C, Khaw, R, Keatley, J, Knight, A, Mann, H, Marson, E, Mclean, K, Mckay, S, Mills, E, Pellino, G, Picciochi, M, Taylor, E, Tiwari, A, Trout, I, Venn, M, JW Wilkin, R, Minaya-Bravo, A, Gallo, G, Moug, S, Saverio, S, Vallance, A, Vimalchandran, D, Griffiths, E, Evans, R, Townend, P, Roberts, K, Isaac, J, Satoi, S, Edwards, J, Coonar, A, Marchbank, A, Caruana, E, Layton, G, Patel, A, Brunelli, A, Ford, S, Desai, A, Gronchi, A, Fiore, M, Almond, M, Tirotta, F, Dumitra, S, Kolias, A, Price, S, Fountain, D, Jenkinson, M, Hutchinson, P, Marcus, H, Piper, R, Lippa, L, Servadei, F, Esene, I, Freyschlag, C, Neville, I, Rosseau, G, Schaller, K, Demetriades, A, Robertson, F, Alamri, A, Shaw, R, Schache, A, Winter, S, Ho, M, Nankivell, P, Biel, J, Batstone, M, Ganly, I, Vidya, R, Wilkins, A, Singh, J, Thekinkattil, D, Sundar, S, Fotopoulou, C, Leung, E, Khan, T, Chiva, L, Sehouli, J, Fagotti, A, Cohen, P, Gutelkin, M, Ghebre, R, Konney, T, Pareja, R, Bristow, R, Dowdy, S, Shylasree, T, Seenivasagam, R, Ng, J, Fujiwara, K, Stewart, G, Lamb, B, Narahari, K, Mcneill, A, Colquhoun, A, Mcgrath, J, Bromage, S, Barod, R, Kasivisvanathan, V, Klatte, T, Abbott, T, Abukhalaf, S, Agarwal, A, Akkulak, M, Alameer, E, Alderson, D, Alakaloko, F, Albertsmeier, M, Alser, O, Alshaar, M, Alshryda, S, Arnaud, A, Augestad, K, Ayasra, F, Azevedo, J, Bankhead-Kendall, B, Barlow, E, Beard, D, Blanco-Colino, R, Brar, A, Breen, K, Bretherton, C, Buarque, I, Burke, J, Chaar, M, Chakrabortee, S, Christensen, P, Cox, D, Cukier, M, Davidson, G, Drake, T, Elhadi, M, Farik, S, Fitzgerald, J, Garmanova, T, Gomes, G, Grecinos, G, Gruendl, M, Halkias, C, Harrison, E, Hisham, I, Hwang, S, Isik, A, Jonker, P, Kaafarani, H, Kruijff, S, Lawani, I, Litvin, A, Loehrer, A, Loffler, M, Lorena, M, Major, P, Martin, J, Mashbari, H, Mazingi, D, Metallidis, S, Moore, R, Moszkowicz, D, Ng-Kamstra, J, Maimbo, M, Negoi, I, Niquen, M, Ntirenganya, F, Olivos, M, Oussama, K, Outani, O, Rivera, C, Pinkney, T, van der Plas, W, Qureshi, A, Radenkovic, D, Ramos-De la Medina, A, Richards, T, Roslani, A, Segura-Sampedro, J, Santos, I, Sayyed, R, Schnitzbauer, A, Seyi-Olajide, J, Sharma, N, Shaw, C, Shu, S, Soreide, K, Spinelli, A, Sund, M, Tabiri, S, Tsoulfas, G, van Ramshorst, G, Vimalachandran, D, Warren, O, Wedderburn, D, Wright, N, Valenzuela, J, Alurralde, C, Caram, E, Eskinazi, D, Badra, R, Garcia, J, Lucchini, S, Vasey, C, Watson, E, Cecire, J, Salindera, S, Sutherland, A, Ahn, J, Chen, S, Gauri, N, Jang, S, Jia, F, Mulligan, C, Yang, W, Ye, G, Zhang, H, Moss, J, Thian, A, Vo, U, Bagraith, K, Chan, E, Ho, D, Jeyarajan, E, Jordan, S, Nolan, G, Von Papen, M, Wullschleger, M, Dawson, A, Drane, A, Egoroff, N, Gani, J, Lott, N, Phan, D, Townend, D, Bong, C, Gundara, J, Bowman, S, Guerra, G, Gerns, N, Riddell, A, Dudi-Venkata, N, Kroon, H, Sammour, T, Mitchell, D, Swinson, B, Waldron, A, Walker, P, Lun, E, Messner, F, Ofner, D, Emmanuel, K, Grechenig, M, Gruber, R, Harald, M, Jager, T, Ohlberger, L, Presl, J, Wimmer, A, Namazov, I, Samadov, E, Barker, D, Boyce, R, Doyle, A, Eastmond, A, Gill, R, O'Shea, M, Padmore, G, Paquette, N, Phillips, E, St John, S, Walkes, K, Flamey, N, Pattyn, P, Ceelen, W, Van de Putte, D, Van Nieuwenhove, Y, Van Ramshorst, G, Willaert, W, Oosterlinck, W, Van den Eynde, J, Van den Eynde, R, Aguiar Junior, S, Marques, T, Camara, P, De Lima, R, Della Giustina, E, Hoffmann, P, Nacif, L, Carvalho Ferro, C, Lima Buarque, I, Lira dos Santos Leite, A, Pol-Fachin, L, Santos Bezerra, T, Silva, A, Silvestre, D, Vieira Barros, A, Laporte, G, Salem, M, Barakat Awada, J, Ijichi, T, Kim, N, Marreiro, A, Muller, B, Nunes, R, Bodanese, B, Isoton, J, Regina de Sampaio, L, Vendrame, C, Sokolov, M, Gribnev, P, Boutros, M, Caminsky, N, Ghitulescu, G, Groot, G, Persad, A, Pham, H, Wood, M, Demyttenaere, S, Garfinkle, R, Brown, C, Karimuddin, A, Lee, N, Liu, J, Madani Kia, T, Phang, P, Raval, M, Tom, K, Martel, A, Nessim, C, Stevenson, J, Al Riyami, S, Bali, K, Bigam, D, Dajani, K, Dell, A, Bellolio, F, Besser, N, Grasset, E, Inzunza, M, Quintana Martinic, M, Riquoir Altamirano, C, Ruiz Esquide, M, Arias-Amezquita, F, Cetares, C, Cortes Murgueitio, N, Gomez-Mayorga, J, Abadia, M, Bonilla, A, Facundo, H, Guevara, O, Herrera Mora, D, Jimenez Ramirez, L, Manrique, E, Pinilla Morales, R, Rey Ferro, M, Velasquez Cuasquen, B, Bacic, G, Karlovic, D, Krsul, D, Zelic, M, Bakmaz, B, Coza, I, Dijan, E, Katusic, Z, Mihanovic, J, Rakvin, I, Almezghwi, H, Arslan, K, Ozant, A, Ozcay, N, Frantzeskou, K, Gouvas, N, Kokkinos, G, Papatheodorou, P, Pozotou, I, Stavrinidou, O, Yiallourou, A, Martinek, L, Skrovina, M, Szubota, I, Peteja, M, Zatecky, J, Avlund, T, Harbjerg, J, Iversen, L, Kjaer, D, Kristensen, H, Mekhael, M, Ebbehoj, A, Krarup, P, Schlesinger, N, Smith, H, Crespo, A, Diaz, P, Rivas, R, Tactuk, N, El Kassas, M, Omar, W, Tawheed, A, Talaat, M, Abdelsamed, A, Azzam, A, Salem, H, Seleim, A, AL Sayed, M, Ashoush, F, Elazzazy, E, Essam, E, Ewedah, M, Hassan, E, Metwalli, M, Mourad, M, Qatora, M, Sabry, A, Samih, A, Samir Abdelaal, A, Shehata, S, Shenit, K, Attia, D, Kamal, N, Osman, N, Alaa, S, Hamza, H, M. elghazaly, S, Mohammed, M, Nageh, M, Saad, M, Yousof, E, Eldaly, A, Alrahawy, M, Sakr, A, Soliman, H, Soltan, H, Amira, G, Sallam, I, Sherief, M, Sherif, A, Ghaly, G, Hamdy, R, Morsi, A, Sherif, G, Abdeldayem, H, Abdelkader Salama, I, Balabel, M, Fayed, Y, Elmorsi, R, Refky, B, Bekele, K, Kauppila, J, Sarjanoja, E, Helminen, O, Huhta, H, Beyrne, C, Jouffret, L, Marie-Macron, L, Fredon, F, Roux, A, Lakkis, Z, Manfredelli, S, Chebaro, A, El Amrani, M, Lecolle, K, Piessen, G, Eveno, C, Noiret, B, Veziant, J, Pruvot, F, Zerbib, P, Ballouhey, Q, Barrat, B, Taibi, A, Bergeat, D, Merdrignac, A, Le Roy, B, Perotto, L, Scalabre, A, Aime, A, Ezanno, A, Malgras, B, Bouche, P, Tzedakis, S, Cotte, E, Glehen, O, Bendjemar, L, Braham, H, Charre, L, El Arbi, N, Police, A, Volpin, E, D'Urso, A, Mutter, D, Seeliger, B, Bonnet, S, Denet, C, Fuks, D, Laforest, A, Pourcher, G, Seguin-givelet, A, Tribillon, E, Duchalais, E, Bork, U, Fritzmann, J, Praetorius, C, Weitz, J, Welsch, T, Beyer, K, Kamphues, C, Lauscher, J, Loch, F, Schineis, C, Kappenberger, A, Schiergens, T, Werner, J, Becker, R, Jonescheit, J, Pergolini, I, Reim, D, Herzberg, J, Honarpisheh, H, Strate, T, Boeker, C, Hakami, I, Mall, J, Nowak, K, Reinhard, T, Kleeff, J, Michalski, C, Ronellenfitsch, U, Bertolani, E, Konigsrainer, A, Quante, M, Steidle, C, Uberruck, L, Yurttas, C, Izbicki, J, Nitschke, C, Perez, D, Uzunoglu, F, Antonakis, P, Contis, I, Dellaportas, D, Gklavas, A, Konstadoulakis, M, Memos, N, Papaconstantinou, I, Polydorou, A, Theodosopoulos, T, Vezakis, A, Antonopoulou, M, Manatakis, D, Tasis, N, Arkadopoulos, N, Danias, N, Economopoulou, P, Frountzas, M, Kokoropoulos, P, Larentzakis, A, Michalopoulos, N, Parasyris, S, Selmani, J, Sidiropoulos, T, Vassiliu, P, Bouchagier, K, Klimopoulos, S, Paspaliari, D, Stylianidis, G, Akrivou, D, Baxevanidou, K, Bouliaris, K, Chatzikomnitsa, P, Delinasios, G, Doudakmanis, C, Efthimiou, M, Giaglaras, A, Kalfountzos, C, Kolla, C, Koukoulis, G, Zervas, K, Zourntou, S, Baloyiannis, I, Diamantis, A, Perivoliotis, K, Tzovaras, G, Christidis, P, Ioannidis, O, Loutzidou, L, Karaitianos, I, Geroukalis, A, Tsirlis, T, Baili, E, Charalabopoulos, A, Liakakos, T, Schizas, D, Spartalis, E, Syllaios, A, Zografos, C, Christou, C, Papadopoulos, V, Tooulias, A, Athanasakis, E, Chrysos, E, Tsiaoussis, I, Xenaki, S, Xynos, E, Futaba, K, Hon, S, Mak, T, Ng, S, Foo, C, Banky, B, Susztak, N, Misra, S, Pareek, P, Vishnoi, J, Jain, A, Mishra, S, Mishra, T, Mitra, J, Muduly, D, Agrawal, A, Garg, P, Kottayasamy Seenivasagam, R, Majumdar, K, Mishra, N, Singh, M, Chyau Patnaik, S, Rao, S, Reddy, P, S, R, Saksena, A, Y, J, Ayloor Seshadri, R, Haque, P, Jeyaraj, P, Kannummal Veetil, S, Mahajan, A, Devarakonda, S, Jesudason, M, Moorthy, M, Yezzaji, H, Aggarwal, M, Dhamija, P, Kumar, A, Chisthi, M, D, G, George, G, Kollengode, V, Kuttanchettiyar, K, Yadev, I, Dharanipragada, K, Kalayarasan, R, Penumadu, P, B, L, Mathew, S, Akhtar, N, Chaturvedi, A, Gupta, S, Kumar, V, Rajan, S, Agrawal, N, Arora, A, Chaturvedi, H, Jain, M, Kumar, S, Singh, S, Bhat, G, Chowdri, N, Mehraj, A, Parray, F, Shah, Z, Wani, R, Ahmed, Z, Bhat, M, Laharwal, A, Mahmood, M, Mir, I, Mohammad, Z, Muzamil, J, Rashid, A, Singh, R, Ahmed, A, Jain, D, Pipara, A, Desoouza, A, Pandey, D, Pramesh, C, Saklani, A, Islam, A, Kembuan, G, Pajan, H, Aremu, M, Canas-Martinez, A, Cullivan, O, Murphy, C, Owens, P, Pickett, L, Corrigan, M, Daly, A, Fleming, C, Jordan, P, Kayyal, M, Killeen, S, Lynch, N, O'Brien, S, Syed, W, Vernon, L, Hanly, A, Heneghan, H, Kennelly, R, Martin, S, Winter, D, Fahey, B, Larkin, J, Mccormick, P, Mehigan, B, Shokuhi, P, Smith, J, Bashir, Y, Bass, G, Connelly, T, Creavin, B, Earley, H, Elliott, J, Gillis, A, Kavanagh, D, Neary, P, O'Riordan, J, Reynolds, I, Rice, D, Ridgway, P, Umair, M, Whelan, M, Corless, K, Finnegan, L, Fowler, A, Hogan, A, Lowery, A, Mckevitt, K, Nugent, E, Ryan, E, Coffey, J, Cunningham, R, Devine, M, Nally, D, Peirce, C, Hardy, N, O'Malley, S, Ryan, M, Gaziants, V, Gold-Deutch, R, Lavy, R, Zmora, O, Macina, S, Mariani, N, Opocher, E, Pisani Ceretti, A, Bianco, F, Marino, M, Mirabella, A, Vaccarella, G, Sena, G, Agostini, C, Alemanno, G, Bartolini, I, Bergamini, C, Bruscino, A, De Vincenti, R, Di Bella, A, Fortuna, L, Maltinti, G, Muiesan, P, Prosperi, P, Ringressi, M, Risaliti, M, Taddei, A, Tucci, R, Campagnaro, T, Guglielmi, A, Pedrazzani, C, Rattizzato, S, Ruzzenente, A, Turri, G, Altomare, D, Papagni, V, Picciariello, A, Bellora, P, D'Aloisio, G, Ferrari, M, Francone, E, Gentilli, S, Nikaj, H, Bianchini, M, Chiarugi, M, Coccolini, F, Cremonini, C, Di Franco, G, Furbetta, N, Gianardi, D, Guadagni, S, Morelli, L, Musetti, S, Palmeri, M, Tartaglia, D, Anania, G, Carcoforo, P, Chiozza, M, De Troia, A, Koleva Radica, M, Portinari, M, Sibilla, M, Urbani, A, Fabbri, N, Feo, C, Gennari, S, Parini, S, Righini, E, Annessi, V, Castro Ruiz, C, Giunta, A, Montella, M, Zizzo, M, Grossi, U, Novello, S, Romano, M, Rossi, S, Zanus, G, Esposito, G, Frongia, F, Pisanu, A, Podda, M, Belluco, C, Lauretta, A, Montori, G, Moras, L, Olivieri, M, Perra, T, Porcu, A, Scanu, A, Aversano, A, Carbone, F, Delrio, P, Di Lauro, K, Fares Bucci, A, Rega, D, Spiezio, G, Pirozzolo, G, Recordare, A, Vignotto, C, Calabro, M, Farnesi, F, Lunghi, E, Muratore, A, Pipitone Federico, N, De Palma, G, Luglio, G, Pagano, G, Tropeano, F, Baldari, L, Boni, L, Cassinotti, E, Cosimelli, M, Guaglio, M, Sorrentino, L, Agnes, A, Alfieri, S, Belia, F, Biondi, A, Cozza, V, D'Ugo, D, De Simone, V, Litta, F, Lorenzon, L, Marra, A, Marzi, F, Parello, A, Persiani, R, Ratto, C, Rosa, F, Scrima, O, Sganga, G, Belli, A, Izzo, F, Patrone, R, Foppa, C, Carvello, M, De Lucia, F, Aprile, A, Batistotti, P, Massobrio, A, Pertile, D, Scabini, S, Soriero, D, De Manzoni Garberini, A, Mazzotti, F, Pasini, F, Ugolini, G, Barone, R, Birolo, S, Caccetta, M, Deirino, A, Garino, M, Grasso, M, Marafante, C, Masciandaro, A, Moggia, E, Mungo, S, Murgese, A, Raggio, E, Federico, P, Maida, P, Marra, E, Marte, G, Petrillo, A, Tammaro, P, Tufo, A, Berselli, M, Borroni, G, Cocozza, E, Conti, L, Desio, M, Rizzi, A, Baldi, C, Corbellini, C, Sampietro, G, Bordoni, P, Clarizia, G, Fleres, F, Franzini, M, Grechi, A, Longhini, A, Spolini, A, Baldini, E, Capelli, P, Isolani, S, Ribolla, M, Bondurri, A, Colombo, F, Ferrario, L, Guerci, C, Maffioli, A, Armao, T, Ballabio, M, Bisagni, P, Longhi, M, Madonini, M, Impellizzeri, H, Inama, M, Moretto, G, Mochet, S, Usai, A, Incollingo, P, Giacometti, M, Zonta, S, Marino Cosentino, L, Sagnotta, A, Nespoli, L, Tamini, N, Anastasi, A, Bartalucci, B, Bellacci, A, Canonico, G, Capezzuoli, L, Di Martino, C, Ipponi, P, Linari, C, Montelatici, M, Nelli, T, Spagni, G, Tirloni, L, Vitali, A, Abate, E, Casati, M, Laface, L, Schiavo, M, Arminio, A, Cotoia, A, Lizzi, V, Vovola, F, Vergari, R, D'Ugo, S, Depalma, N, Spampinato, M, Annicchiarico, A, Catena, F, Giuffrida, M, Perrone, G, Baronio, G, Carissimi, F, Montuori, M, Pinotti, E, Brachini, G, Chiappini, A, Cicerchia, P, Cirillo, B, De Toma, G, Fiori, E, Fonsi, G, Iannone, I, La Torre, F, Lapolla, P, Meneghini, S, Mingoli, A, Sapienza, P, Zambon, M, Capolupo, G, Carannante, F, Mazzotta, E, Gattolin, A, Migliore, M, Rimonda, R, Sasia, D, Travaglio, E, Chessa, A, Fiorini, A, Norcini, C, Colletti, G, Confalonieri, M, Costanzi, A, Frattaruolo, C, Mari, G, Monteleone, M, Locatelli, A, Riva, C, Balconi, A, De 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R., Choong E., Lim R. Z. M., Sahid N. A., Hayati F., Jayasilan J., Sriram R. K., Subramaniam S., Ibrahim A. F., Che jusoh A., Hussain A. H., Mohamed Sidek A. S., Mohd Yunus M. F., Soh J. Y., Wong M. P., Zakaria A. D., Zakaria Z., Mohd Azman Z. A., Fathi N. Q., Xavier R., Alvarez M. R., Cordera F., Hernandez R., Soule Martinez C. E., Aboharp Hasan Z., Otoniel L. R., Sosa Duran E. E., Melchor-Ruan J., Romero Banuelos E., Vilar-Compte D., Buerba G. A., Mercado M. A., Posadas-Trujillo O. E., Salgado-Nesme N., Sarre C., Amrani L., Benkabbou A., El Ahmadi B., El Bouazizi Y., Belkhadir Z. H., Ghannam A., Majbar A. M., Mohsine R., Souadka A., Hompes R., Meima-van Praag E. M., Pronk A. J. M., Sharabiany S., Grotenhuis B. A., Hartveld L., Ebben L., Kuiper S., Melenhorst J., Poeze M., Posma-Bouman L., Derksen T., Franken J., Oosterling S., Konsten J., Van Heinsbergen M., Adeyeye A., Enoch E., Nwabuoku S. E., Sholadoye T. T., Tolani M. 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A., Fernandes V., Ferraz I., Lima da Cruz L., Lima da Silva C., Lopes L., Machado N., Marialva J., Nunes Coelho M., Pedro J., Pereira C., Ribeiro A., Ribeiro C. G., Santos R., Saraiva P., Silva R., Tavares F., Teixeira M., Almeida A. C., Amaral M. J., Andrade R., Camacho C., Costa M., Lazaro A., Nogueira O., Oliveira A., Ruivo A., Silva M., Simoes J. F. F., Devezas V., Jacome F., Nogueiro J., Pereira A., Santos-Sousa H., Vaz S., Pinto J., Tojal A., Cardoso P., Martins R., Martins dos Santos G., Henriques P., Morais H., Sousa S., Cardoso N., Teixeira J., Pereira R., Revez T., Ribeiro R., Manso I., Domingues J., Amorim E., Baptista V. H., Sampaio da Novoa Gomes Miguel I. I., Bandovas J. P., Borges N., Chumbinho B., Figueiredo de Barros I., Frade S., Gomes J., Kam da Silva Andrade A., Pereira Rodrigues A., Pina S., Silva N., Silveira Nunes I., Sousa R., Azevedo P., Costeira B., Cunha C., Garrido R., Miranda P., Peralta Ferreira M., Sousa Fernandes M., Galvao D., Vieira A., Patricio B., Santos P. M. D. D., Vieira Paiva Lopes A. C., Cunha R., Faustino A., Freitas A., Mendes J. R., Parreira R., Abreu da Silva A., Claro M., Costa Santos D., Deus A. C., Grilo J. V., Castro Borges F., Corte Real J., Henriques S., Lima M. J., Matos Costa P., Alagoa Joao A., Camarneiro R., Capunge I., Fragoso M., Frazao J., Martins A., Pedro V., Pera R., Ramalho de Almeida F., Sampaio Soares A., Vale R., Vasconcelos M., Brito da Silva F., Caiado A., Fonseca F., Angelo M., Baiao J. M., Martins Jordao D., Vieira Caroco T., Baia C., Canotilho R., Correia A. M., Ferreira Pinto A. P., Peyroteo M., Videira J. F., Kassir R., Sauvat F., Bonci E., Gata V., Titu S., Bezede C., Chitul A., Ciofic E., Cristian D., Grama F., Ciubotaru C., Negoita V. M., Stoica B., Ginghina O., Iordache N., Iosifescu R. V., Mardare M., Mirica R. M., Spanu A., Vacaras A. B., Zamfir-Chiru-Anton M., Tsarkov P., Tulina I., Abelevich A., Bazaev A., Kokobelyan A. K., Yanishev A., Litvina Y., Provozina A., Agapov M., Kazachenko E., Markaryan D., Galliamov E., Kakotkin V., Kubyshkin V., Semina E., Kamalov A., Novikova A., Zakharenko A., Alshahrani M., Alsharif F., Eskander M., Majrashi S., Mashat A., Alharthi M., Aljiffry M., Basendowah M., Malibary N., Nassif M., Samkari A., Trabulsi N., Azab M. A., Alqahtani D., Jaloun H., Mudawi I., Al Awwad S., Alghamdi M., Alnumani T., Awad S., I Sharara M., Al Habes H., Alqannas M., Alyami M., Alzamanan M., Cortes-Guiral D., Elawad A., Adi H., Al ahmad F., Al Ayed A., Alishi Y., AlAamer O., Alselaim N., Alfaifi J., D'Souza J., Al-Khayal K., Alhassan N., Alobeed O., Alshammari S., Bin Nasser A., Bin Traiki T., Nouh T., Zubaidi A., Abdulfattah F., Al-Kharashi E., Alanazi F., Albaqami F., Alghuliga A., Alsowaina K., Arab N., Badahdah F., Alobaysi S., Alshahrani A., Alzahrani A., Aleksic L., Antic A., Barisic G., Ceranic M., Grubac Z., Jelenkovic J., Kecmanovic D., Kmezic S., Knezevic D., Krivokapic Z., Latincic S., Markovic V., Matic S., Miladinov M., Pavlov M., Pejovic I., Tadic B., Vasljevic J., Velickovic D., Doklestic K., Gregoric P., Ivancevic N., Loncar Z., Micic D., Buta M., Cvetkovic A., Gacic S., Goran M., Jeftic N., Markovic I., Milanovic M., Nikolic S., Pejnovic L., Savkovic N., Stevic D., Vucic N., Zegarac M., Karamarkovic A., Kenic M., Milic L. J., Kovacevic B., Krdzic I., Lieske B., Almgla N., Boutall A., Herman A., Kloppers C., Nel D., Rayamajhi S., Paniagua Garcia Senorans M., Vigorita V., Acrich E., Baena Sanfeliu E., Barrios O., Golda T., Santanach C., Serrano-Navidad M., Sorribas Grifell M., Vives R. V., Escola D., Jimenez A., Alcazar J. A., Angoso-Clavijo M., Blanco-Antona F., Carabias-Orgaz A., Diaz Maag R., Garcia J., Garcia-Plaza A. G. P., Gonzalez-Munoz J. I., Munoz-Bellvis L., Sanchez Tocino J. M., Sanchez-Casado A. B., Trebol J., Hernandez Gutierrez J., Tebar Zamora A., Palma P., Cayetano Paniagua L., Gomez Fernandez L., Collera Ormazabal P., Diaz del Gobbo R., Farre Font R., Flores Clotet R., Gomez Diaz C. J., Guardia N., Guariglia C. A., Osorio Ramos A., Sanchez Jimenez R., Sanchon L., Soto Montesinos C., Alonso-Lamberti L., Garcia-Quijada J., Jimenez Miramon J., Jimenez V., Jover J. M., Leon R., Rodriguez J. L., Salazar A., Valle Rubio A., Aguado Lopez H., Bravo Infante R., De Lacy F. B., Lacy A. M., Otero A., Turrado-Rodriguez V., Valverde S., Anula R., Avellana R., Camarero Rodriguez E., Catalan Garza V., Dziakova J., Garcia Alonso M., Lasses Martinez B., Lopez Antonanzas L., Muguerza J. M., Ochagavia S., Pena Soria M. J., Rivera-Alonso D., Saez Carlin P., Sanchez del Pueblo C., Sanz Ortega G., Sanz-Lopez R., Torres A., Martin-Arevalo J., Moro-Valdezate D., Pla-Marti V., Beltran de Heredia J., De Andres-Asenjo B., Gomez Sanz T., Jezieniecki C., Nunez Del Barrio H., Ortiz de Solorzano Aurusa F. J., Romero de Diego A., Ruiz Soriano M., Trujillo Diaz J., Vazquez Fernandez A., Lora-Cumplido P., Sosa-Rodriguez M. V., Galvan Perez A., Gonzalez-Gonzalez E., Minaya Bravo A. M., San Miguel C., Alonso de la Fuente N., Jimenez Toscano M., Grau-Talens E. J., Martin-Perez B., Benavides Buleje J. A., Carrasco Prats M., Gimenez Frances C., Munoz Camarena J. M., Parra Banos P. A., Pena Ros E., Ramirez Faraco M., Ruiz-Marin M., Valero Soriano M., Allue M., Colsa P., Garcia Dominguez M., Gimenez Maurel T., Martin Anoro L. F., Ponchietti L., Rodriguez Artigas J. M., Roldon Golet M., Utrilla Fornals A., Estaire Gomez M., Fernandez Camunas A., Garcia Santos E. P., Jimenez Higuera E., Martinez-Pinedo C., Munoz-Atienza V., Padilla-Valverde D., Picon Rodriguez R., Sanchez-Garcia S., Sanchez-Pelaez D., Curtis Martinez C., Sanchez-Guillen L., Colombari R. C., Del valle E., Fernandez M., Lozano Lominchar P., Martin L., Rey Valcarcel C., Zorrilla Ortuzar J., Alcaide Matas F., Garcia Perez J. M., Troncoso Pereira P., Blas Laina J. L., Cros B., Escartin J., Garcia Egea J., Nogues A., Talal El-Abur I., Yanez C., Mora-Guzman I., Achalandabaso Boira M., Sales Mallafre R., Marin H., Prieto Calvo M., Villalabeitia Ateca I., De Andres Olabarria U., Duran Ballesteros M., Fernandez Pablos F. J., Ibanez-Aguirre F. J., Sanz Larrainzar A., Ugarte-Sierra B., Acosta Merida M. A., Ortiz Lopez D., Yepes Cano A. F., Correa Bonito A., Delgado Burdalo L., Di Martino M., Garcia Septiem J., Maqueda Gonzalez R., Martin-Perez E., Calvo Espino P., Guillamot Ruano P., Colao Garcia L., Diaz Perez D., Esteban Agusti E., Galindo Jara P., Gutierrez Samaniego M., Hernandez Bartolome M. A., Serrano Gonzalez J., Alonso Poza A., Dieguez B., Garcia-Conde M., Hernandez-Garcia M., Losada M., Alvarez E., Chavarrias N., Gegundez Simon A., Gortazar de las Casas S., Guevara-Martinez J., Prieto Nieto M. I., Ramos-Martin P., Rubio-Perez I., Saavedra J., Urbieta A., Aparicio-Lopez D., Cantalejo diaz M., De Miguel Ardevines M. D. C., Dobon Rascon M. A., Duque-Mallen V., Gascon Ferrer I., Gonzalez-Nicolas Trebol M. T., Gracia-Roche C., Herrero Lopez M., Kalviainen H., Martinez German A., Matute M., Sanchez Fuentes N., Santero-Ramirez M. 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D., Torres Arcos C., Valdes-Hernandez J., Cholewa H., Frasson M., Martinez Chicote C., Sancho-Muriel J., Estraviz B., Fernandez Gomez Cruzado L., Gonzalez de Miguel M., Landaluce-olavarria A., Abad-Gurumeta A., Abad-Motos A., Martinez-Hurtado E., Ripolles-Melchor J., Ruiz-Escobar A., Cuadrado-Garcia A., Garcia-Sancho Tellez L., Heras Aznar J., Mate Mate P., Ortega Vazquez I., Picardo A. L., Rojo Lopez J. A., Sanchez Cabezudo Noguera F., Serralta de Colsa D., Cagigas Fernandez C., Caina Ruiz R., Gomez Ruiz M., Martinez-Perez P., Santarrufina Martinez S., Valbuena Jabares V., Cagigal Ortega E. P., Cervera I., Diaz Pena P., Gonzalez J., Marqueta De Salas M., Perez Gonzalez M., Ramos Bonilla A., Rodriguez Gomez L., Alfonso Garcia M., Craus-Miguel A., Fernandez Vega L., Ferrer-Inaebnit E., Gil Catalan A., Gonzalez Argente F. X., Jeri S., Oseira A., Pujol Cano N., Soldevila Verdeguer C., Villalonga B., Espin-Basany E., Srishankar S., Thalgaspitiya S. P. B., Arulanantham A., Bandara G. B. K. 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N., Uludag S. S., Velidedeoglu M., Zengin A. K., Kara Y., Bozkurt M. A., Kocatas A., Eyuboglu K., Guner A., Usta M. A., Azamat I. F., Balik E., Bugra D., Kulle C. B., Guler S. A., Guresin A., Tatar O. C., Utkan N. Z., Yildirim A., Yuksel E., Abbasov A., Yanar H., Akin E., Altintoprak F., Cakmak G., Celebi F., Demir H., Dikicier E., Firat N., Gonullu E., Kamburoglu M. B., Kucuk I. F., Mantoglu B., Colak E., Kucuk G. O., Uyanik M. S., Goksoy B., Bozkurt E., Capkinoglu E., Guven O., Mihmanli M., Omeroglu S., Tanal M., Yetkin G., Akalin M., Arican C., Avci E. K., Aydin C., Demirli Atici S., Emiroglu M., Kaya T., Kebabci E., Kilinc Tuncer G., Kirmizi Y., Ogucu H., Salimoglu S., Sert I., Tugmen C., Tuncer K., Uslu G., Yesilyurt D., Yildiz A., Gultekin F. A., Lule H., Oguttu B., Agilinko J., Ahmeidat A., Bekheit M., Cheung L. K., Kamera B. S., Mignot G., Shaikh S., Sharma P., Al-Mohammad A., Ali S., Ashcroft J., Baker O., Coughlin P., Davies R. 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D., Verberne C., Anscomb N., Baldwin-Smith R., Davies M., Grainger C., Haji A., Haq A., Nunoo-Mensah J. W., Rizk M., Bhatti M. I., Boyd-Carson H., Elsey E., Gemmill E., Herrod P., MohammedJibreel M., Lenzi E., Saafan T., Sapre D., Sian T., Watson N., Athanasiou A., Costigan F., Elkadi H., Johnstone J., Nahm C., Annamalai S., Ashmore C., Kourdouli A., Chean C. S., Dharamavaram S., Kulkarni N., Pereira I., Shanthakunalan K., Srikumar B., Askari A., Cirocchi N., Kudchadkar S., Patel K., Sagar J., Talwar R., Abdalla M., Ismail O., Newton K., Stylianides N., Aderombi A., Bajomo O., Beatson K., Garrett W. V., Ng V., Al-Habsi R., Divya G. S., Dixon F., Keeler B. D., Egan R. J., Fabre I., Harries R., Li Z., Parkins K., Spencer N., Thompson D., Gemmell C., Grieco C., Hunt L., Mahmoud Ali F., Seebah K., Shaikh I., Sreedharan L., Youssef M., Shah J., Baguley M., Heer B., Rogers M., Woods R., Mills S. J., Sahnan K., Ahmed M. E., Bukhari S. I., Illingworth B., Kanthasamy S., Knights E., Ong S. 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M., Williams G., Davies E., Hawkin P., Raymond T., Ryska O., Baron R., Gahunia S., McNicol F., Russ J., Szatmary P., Thomas A., Jayasinghe J. D., Knowles C., Ledesma F. S., Minicozzi A., Navaratne L., Ramamoorthy R., Sohrabi C., Thaha M. A., Venn M., Atherton R., Brocklehurst M., McAleer J., Parkin E., Aladeojebi A., Ali M., Gaunt A., Hammer C., Stebbing J., Coomber E., Williams O., Bunni J., Fairhurst K., Mitchell S., Richards S., Hraishawi I., McIlmunn C., McIntosh S., Bhasin S., Bodla A. S., Burahee A., Crichton A., Fossett R., Yassin N., Barlow C., Ding D., Foster J., Longstaff L., Brown S. R., Lee M., Newman T., Steele C., Baker A., Konstantinou C., Ramcharan S., Wilkin R. J. W., Colvin H. V., Shakoor Z., Lyons A., Newman S., Chung E., Hagger R., Hainsworth A., Karim A., Owen H., Ramwell A., Williams K., Hall J., Harris G., Royle T., Watson L. J., Asaad P., Brown B., Duff S., Khan A., Moura F., Wadham B., Mccluney S., Parmar C., Shah S., Babar M. S., Goodrum S., Whitmore H., Balasubramaniam D., Jayasankar B., Kapoor S., Ramachandran A., Beech N., Chand M., Green L., Kiconco H., McEwen R., Pereca J., Arumugam S., Ibrahim B., Khan K., Gash K., Gourbault L., Maccabe T. A., Newton C., Baig M., Bates H., Dunne N., Khajuria A., Sarma D. R., Shortland T., Tewari N., Akhtar M. A., Brunt A., McIntyre J., Milne K., Rashid M. M., Sgro A., Stewart K. E., Turnbull A., Gossedge G., O'Donnell S., Oldfield F., Aguilar Gonzalez M., Talukder S., Eskander P., Hanna M., Olivier J., Basnyat P., Davis H., Montauban P., Shrestha A., Magee C., Powell S., Flindall I., Hanson A., Mahendran V., Green S., Lim M., MacDonald L., Miu V., Onos L., Sheridan K., Young R., Alam F., Griffiths O., Houlden C., Kolli V. S., Lala A. K., Seymour Z., Consorti E., Gonzalez R., Kwan-Feinberg R., Liu T., Cooper Z., Hirji S., Mahvi D., Okafor B., Roxo V., Salim A., Telma K., Bokenkamp M., Haynes A. B., Hill C., Leede E., McElhinney K., Olson K. 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D., Torres Arcos C., Valdes-Hernandez J., Cholewa H., Frasson M., Martinez Chicote C., Sancho-Muriel J., Estraviz B., Fernandez Gomez Cruzado L., Gonzalez de Miguel M., Landaluce-olavarria A., Abad-Gurumeta A., Abad-Motos A., Martinez-Hurtado E., Ripolles-Melchor J., Ruiz-Escobar A., Cuadrado-Garcia A., Garcia-Sancho Tellez L., Heras Aznar J., Mate Mate P., Ortega Vazquez I., Picardo A. L., Rojo Lopez J. A., Sanchez Cabezudo Noguera F., Serralta de Colsa D., Cagigas Fernandez C., Caina Ruiz R., Gomez Ruiz M., Martinez-Perez P., Santarrufina Martinez S., Valbuena Jabares V., Cagigal Ortega E. P., Cervera I., Diaz Pena P., Gonzalez J., Marqueta De Salas M., Perez Gonzalez M., Ramos Bonilla A., Rodriguez Gomez L., Alfonso Garcia M., Craus-Miguel A., Fernandez Vega L., Ferrer-Inaebnit E., Gil Catalan A., Gonzalez Argente F. X., Jeri S., Oseira A., Pujol Cano N., Soldevila Verdeguer C., Villalonga B., Espin-Basany E., Srishankar S., Thalgaspitiya S. P. B., Arulanantham A., Bandara G. B. K. 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- Abstract
Aim: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. Methods: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January–April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. Results: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90–1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69–1.27, P = 0.672). Longer delays were not associated with poorer outcomes. Conclusion: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease.
- Published
- 2022
109. Molecular markers of adipose tissue function during the febrile response
- Author
-
Eastmond, Nigel C.
- Subjects
610 ,Thermoregulation ,Fever - Abstract
Fever has been shown to increase metabolic rate and there is evidence that there is an induction of heat production in brown adipose tissue (BAT). This thesis examines heat production in BAT during fever by measuring GDP-binding to BAT mitochondria and the gene expression of UCP and lipoprotein lipase (LPL). Rats were injected iv. with lipopolysaccharide (LPS; 10 μg/kg body weight) and developed a triphasic fever characterized by an initial decrease in core temperature. Ketoprofen (3 mg/kg body weight), an inhibitor of prostaglandin synthesis, attenuated the increases in core temperature throughout the response but had no effect on the initial hypothermia. Animals made febrile with LPS showed no increase in GDP-binding to BAT mitochondria when compared to saline controls. UCP mRNA and LPL mRNA levels in BAT were also unaffected by the fever. Acute cold exposure induced increases in all of the above parameters. Measurements of the quantity of ob mRNA and LPL mRNA in the WAT of febrile rats revealed no changes in the expression of either gene. Acute cold exposure decreased the levels of ob mRNA, with smaller, but statistically insignificant decreases in LPL mRNA. Genetically obese (fa/fa) Zucker rats and lean controls responded to iv. LPS (10 μg/kg body weight) with a fever characterized by an initial hypothermia. The obese rats had lower levels of UCP mRNA in BAT, but not LPL mRNA, than lean controls. In addition, levels of ob mRNA were considerably elevated in the obese variant but, surprisingly, these differences were not statistically significant. It is concluded that fever does not necessarily involve thermogenesis in BAT and, that changes in energy balance during fever are not manifested as changes in the expression of the ob gene in WAT.
- Published
- 1995
110. From milpa to citrus : opportunity or risk? a study of two villages in Yucatan, Mexico
- Author
-
Eastmond, Amarella
- Subjects
301 ,Agricultural modernisation - Published
- 1994
111. Silence and Transitional Justice
- Author
-
Eastmond, Marita, Mannergren Selimovic, Johanna, Eastmond, Marita, and Mannergren Selimovic, Johanna
- Abstract
This chapter examines the role of silence in transitional justice. Silence is more than the absence of speech since silence in human societies can serve numerous purposes in human interaction, social meanings, and political implications. Moreover, silence conveys difficult experiences and sensitive messages more effectively than speech, which also assists in rebuilding trust and restoring relations. The chapter also elaborates on the broad range of possibilities silence offers as a means of communication in war-torn communities. It cites that silence and its semantic and performative potential opens up critical enquiries into the disjunctures between the transitional justice paradigm and the lived experiences of transitions.
- Published
- 2023
- Full Text
- View/download PDF
112. Numerical studies of two problems in condensed matter physics : quantum transport and quantum antiferromagnets
- Author
-
Eastmond, John F. G.
- Subjects
530.41 ,Solid-state physics - Published
- 1992
113. Royal imagery in the medieval Kingdom of Georgia 786-1213
- Author
-
Eastmond, Antony Deyman
- Subjects
700 ,Arts - Published
- 1992
114. Bridging Boundaries? The Effect of Genetic Ancestry Testing on Ties across Racial Groups.
- Author
-
Roth, Wendy D, Côté, Rochelle, and Eastmond, Jasmyne
- Subjects
GENETIC testing ,SOCIAL impact ,RANDOMIZED controlled trials ,SOCIAL capital ,RACE ,NATIVE American women ,ASIANS - Abstract
The phenomenon of widespread genetic ancestry testing has raised questions about its social impact, particularly on issues of race. Some accounts suggest testing can promote bridging social capital – connections between racial groups. In this multi-method paper, we ask whether (1) taking genetic ancestry tests (GATs) and (2) receiving results of African, Asian, or Native American ancestry increases network racial diversity for White Americans. We use a randomized controlled trial of 802 White, non-Hispanic Americans, half of whom received GATs. Unexpected findings show that test-takers' network racial diversity decreases after testing. Using 58 follow-up interviews, we develop and test a possible theory, finding initial evidence that test-takers' network racial diversity declines because they reconsider their racial appraisals of others in their networks. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
115. Ketocarotenoid production in tomato triggers metabolic reprogramming and cellular adaptation: The quest for homeostasis.
- Author
-
Nogueira, Marilise, Enfissi, Eugenia M. A., Price, Elliott J., Menard, Guillaume N., Venter, Eudri, Eastmond, Peter J., Bar, Einat, Lewinsohn, Efraim, and Fraser, Paul D.
- Subjects
METABOLIC reprogramming ,TOMATOES ,OXIDATION-reduction reaction ,METABOLITES - Abstract
Summary: Plants are sessile and therefore have developed an extraordinary capacity to adapt to external signals. Here, the focus is on the plasticity of the plant cell to respond to new intracellular cues. Ketocarotenoids are high‐value natural red pigments with potent antioxidant activity. In the present study, system‐level analyses have revealed that the heterologous biosynthesis of ketocarotenoids in tomato initiated a series of cellular and metabolic mechanisms to cope with the formation of metabolites that are non‐endogenous to the plant. The broad multilevel changes were linked to, among others, (i) the remodelling of the plastidial membrane, where the synthesis and storage of ketocarotenoids occurs; (ii) the recruiting of core metabolic pathways for the generation of metabolite precursors and energy; and (iii) redox control. The involvement of the metabolites as regulators of cellular processes shown here reinforces their pivotal role suggested in the remodelled 'central dogma' concept. Furthermore, the role of metabolic reprogramming to ensure cellular homeostasis is proposed. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
116. Risk of Gynecological Cancers in Women With Polycystic Ovary Syndrome and the Pathophysiology of Association
- Author
-
Shetty, Chaitra, primary, Rizvi, Syed Muhammad Hannan Ali, additional, Sharaf, Joudi, additional, Williams, Kerry-Ann D, additional, Tariq, Maha, additional, Acharekar, Maitri V, additional, Guerrero Saldivia, Sara Elena, additional, Unnikrishnan, Sumedha N, additional, Chavarria, Yeny Y, additional, Akindele, Adebisi O, additional, Jalkh, Ana Paula C, additional, Eastmond, Aziza K, additional, and Hamid, Pousette, additional
- Published
- 2023
- Full Text
- View/download PDF
117. Supplementary Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1
- Author
-
Pennington, Katie L., primary, McEwan, Colten M., primary, Woods, James, primary, Muir, Colin M., primary, Pramoda Sahankumari, A.G., primary, Eastmond, Riley, primary, Balasooriya, Eranga R., primary, Egbert, Christina M., primary, Kaur, Sandeep, primary, Heaton, Tyler, primary, McCormack, Katherine K., primary, Piccolo, Stephen R., primary, Kurokawa, Manabu, primary, and Andersen, Joshua L., primary
- Published
- 2023
- Full Text
- View/download PDF
118. Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1
- Author
-
Pennington, Katie L., primary, McEwan, Colten M., primary, Woods, James, primary, Muir, Colin M., primary, Pramoda Sahankumari, A.G., primary, Eastmond, Riley, primary, Balasooriya, Eranga R., primary, Egbert, Christina M., primary, Kaur, Sandeep, primary, Heaton, Tyler, primary, McCormack, Katherine K., primary, Piccolo, Stephen R., primary, Kurokawa, Manabu, primary, and Andersen, Joshua L., primary
- Published
- 2023
- Full Text
- View/download PDF
119. Insecticide transfer efficiency and lethal load in Argentine ants
- Author
-
Hooper-Bui, L.M., Kwok, E.S.C., Buchholz, B.A., Rust, M.K., Eastmond, D.A., and Vogel, J.S.
- Published
- 2015
- Full Text
- View/download PDF
120. IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk
- Author
-
MacGregor, James T., Frötschl, Roland, White, Paul A., Crump, Kenny S., Eastmond, David A., Fukushima, Shoji, Guérard, Melanie, Hayashi, Makoto, Soeteman-Hernández, Lya G., Johnson, George E., Kasamatsu, Toshio, Levy, Dan D., Morita, Takeshi, Müller, Lutz, Schoeny, Rita, Schuler, Maik J., and Thybaud, Véronique
- Published
- 2015
- Full Text
- View/download PDF
121. IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs)
- Author
-
MacGregor, James T., Frötschl, Roland, White, Paul A., Crump, Kenny S., Eastmond, David A., Fukushima, Shoji, Guérard, Melanie, Hayashi, Makoto, Soeteman-Hernández, Lya G., Kasamatsu, Toshio, Levy, Dan D., Morita, Takeshi, Müller, Lutz, Schoeny, Rita, Schuler, Maik J., Thybaud, Véronique, and Johnson, George E.
- Published
- 2015
- Full Text
- View/download PDF
122. Risk of Gynecological Cancers in Women With Polycystic Ovary Syndrome and the Pathophysiology of Association
- Author
-
Chaitra Shetty, Syed Muhammad Hannan Ali Rizvi, Joudi Sharaf, Kerry-Ann D Williams, Maha Tariq, Maitri V Acharekar, Sara Elena Guerrero Saldivia, Sumedha N Unnikrishnan, Yeny Y Chavarria, Adebisi O Akindele, Ana Paula C Jalkh, Aziza K Eastmond, and Pousette Hamid
- Subjects
General Engineering - Published
- 2023
- Full Text
- View/download PDF
123. Supplementary Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1
- Author
-
Joshua L. Andersen, Manabu Kurokawa, Stephen R. Piccolo, Katherine K. McCormack, Tyler Heaton, Sandeep Kaur, Christina M. Egbert, Eranga R. Balasooriya, Riley Eastmond, A.G. Pramoda Sahankumari, Colin M. Muir, James Woods, Colten M. McEwan, and Katie L. Pennington
- Abstract
Supplementary Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1
- Published
- 2023
- Full Text
- View/download PDF
124. Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1
- Author
-
Joshua L. Andersen, Manabu Kurokawa, Stephen R. Piccolo, Katherine K. McCormack, Tyler Heaton, Sandeep Kaur, Christina M. Egbert, Eranga R. Balasooriya, Riley Eastmond, A.G. Pramoda Sahankumari, Colin M. Muir, James Woods, Colten M. McEwan, and Katie L. Pennington
- Abstract
PTOV1 is an oncogenic protein, initially identified in prostate cancer, that promotes proliferation, cell motility, and invasiveness. However, the mechanisms that regulate PTOV1 remain unclear. Here, we identify 14-3-3 as a PTOV1 interactor and show that high levels of 14-3-3 expression, like PTOV1, correlate with prostate cancer progression. We discover an SGK2-mediated phosphorylation of PTOV1 at S36, which is required for 14-3-3 binding. Disruption of the PTOV1–14–3-3 interaction results in an accumulation of PTOV1 in the nucleus and a proteasome-dependent reduction in PTOV1 protein levels. We find that loss of 14-3-3 binding leads to an increase in PTOV1 binding to the E3 ubiquitin ligase HUWE1, which promotes proteasomal degradation of PTOV1. Conversely, our data suggest that 14-3-3 stabilizes PTOV1 protein by sequestering PTOV1 in the cytosol and inhibiting its interaction with HUWE1. Finally, our data suggest that stabilization of the 14-3-3–bound form of PTOV1 promotes PTOV1-mediated expression of cJun, which drives cell-cycle progression in cancer. Together, these data provide a mechanism to understand the regulation of the oncoprotein PTOV1.Implications:These findings identify a potentially targetable mechanism that regulates the oncoprotein PTOV1.
- Published
- 2023
- Full Text
- View/download PDF
125. Birds and Bioenergy within the Americas: A Cross-National, Social–Ecological Study of Ecosystem Service Tradeoffs
- Author
-
Jessie L. Knowlton, Kathleen E. Halvorsen, David J. Flaspohler, Christopher R. Webster, Jesse Abrams, Sara M. Almeida, Stefan L. Arriaga-Weiss, Brad Barnett, Maíra R. Cardoso, Pablo V. Cerqueira, Diana Córdoba, Marcos Persio Dantas-Santos, Jennifer L. Dunn, Amarella Eastmond, Gina M. Jarvi, Julian A. Licata, Ena Mata-Zayas, Rodrigo Medeiros, M. Azahara Mesa-Jurado, Lízbeth Yamily Moo-Culebro, Cassandra Moseley, Erik Nielsen, Colin C. Phifer, Erin C. Pischke, Chelsea Schelly, Theresa Selfa, Chelsea A. Silva, Tatiana Souza, Samuel R. Sweitz, and César J. Vázquez-Navarrete
- Subjects
aspen ,biodiversity ,Elaeis guineensis ,eucalyptus ,land use change ,oil palm ,Agriculture - Abstract
Although renewable energy holds great promise in mitigating climate change, there are socioeconomic and ecological tradeoffs related to each form of renewable energy. Forest-related bioenergy is especially controversial, because tree plantations often replace land that could be used to grow food crops and can have negative impacts on biodiversity. In this study, we examined public perceptions and ecosystem service tradeoffs between the provisioning services associated with cover types associated with bioenergy crop (feedstock) production and forest habitat-related supporting services for birds, which themselves provide cultural and regulating services. We combined a social survey-based assessment of local values and perceptions with measures of bioenergy feedstock production impacts on bird habitat in four countries: Argentina, Brazil, Mexico, and the USA. Respondents in all countries rated birds as important or very important (83–99% of respondents) and showed lower enthusiasm for, but still supported, the expansion of bioenergy feedstocks (48–60% of respondents). Bioenergy feedstock cover types in Brazil and Argentina had the greatest negative impact on birds but had a positive impact on birds in the USA. In Brazil and Mexico, public perceptions aligned fairly well with the realities of the impacts of potential bioenergy feedstocks on bird communities. However, in Argentina and the USA, perceptions of bioenergy impacts on birds did not match well with the data. Understanding people’s values and perceptions can help inform better policy and management decisions regarding land use changes.
- Published
- 2021
- Full Text
- View/download PDF
126. Barriers and Solutions to Conducting Large International, Interdisciplinary Research Projects
- Author
-
Pischke, Erin C., Knowlton, Jessie L., Phifer, Colin C., Gutierrez Lopez, Jose, Propato, Tamara S., Eastmond, Amarella, de Souza, Tatiana Martins, Kuhlberg, Mark, Picasso Risso, Valentin, Veron, Santiago R., Garcia, Carlos, Chiappe, Marta, and Halvorsen, Kathleen E.
- Published
- 2017
- Full Text
- View/download PDF
127. Sustainable Development for Whom and How? Exploring the Gaps between Popular Discourses and Ground Reality Using the Mexican Jatropha Biodiesel Case
- Author
-
Banerjee, Aparajita, Halvorsen, Kathleen E, Eastmond-Spencer, Amarella, and Sweitz, Sam R
- Published
- 2017
- Full Text
- View/download PDF
128. Mexico
- Author
-
Eastmond, Amarella, García, Carlos, Fuentes, Alfredo, Becerril-García, Javier, Solomon, Barry D., editor, and Bailis, Robert, editor
- Published
- 2014
- Full Text
- View/download PDF
129. High-Throughput Method for Detection of Arbovirus Infection of Saliva in Mosquitoes Aedes aegypti and Ae. albopictus
- Author
-
Nildimar Alves Honório, Daniel Cardoso Portela Câmara, Keenan Wiggins, Bradley Eastmond, and Barry Wilmer Alto
- Subjects
mosquito vectors ,vector competence ,saliva assay ,transmission ,arbovirus surveillance ,Microbiology ,QR1-502 - Abstract
Vector competence refers to the ability of a vector to acquire, maintain, and transmit a pathogen. Collecting mosquito saliva in medium-filled capillary tubes has become the standard for approximating arbovirus transmission. However, this method is time-consuming and labor-intensive. Here we compare the capillary tube method to an alternative high-throughput detection method the collection of saliva on paper cards saturated with honey, with (FTA card) and without (filter paper) reagents for the preservation of nucleic acid for Aedes aegypti and Aedes albopictus mosquitoes infected with two emerging genotypes of the chikungunya virus (CHIKV). Model results showed that the Asian genotype CHIKV dissemination in the harvested legs of both Ae. aegypti and Ae. albopictus increased the odds of females having a positive salivary infection and higher salivary viral titers, while for the IOL genotype the same effect was observed only for Ae. aegypti. Of the three tested detection methods, the FTA card was significantly more effective at detecting infected saliva of Ae. aegypti and Ae. albopictus females than the capillary tube and filter paper was as effective as the capillary tube for the Asian genotype. We did not find significant effects of the detection method in detecting higher viral titer for both Asian and IOL genotypes. Our results are discussed in light of the limitations of the different tested detection methods.
- Published
- 2020
- Full Text
- View/download PDF
130. Effect of Oral Infection of Mayaro Virus on Fitness Correlates and Expression of Immune Related Genes in Aedes aegypti
- Author
-
Barry W. Alto, Ayse Civana, Keenan Wiggins, Bradley Eastmond, and Dongyoung Shin
- Subjects
mosquito ,arbovirus infection ,immune response ,cost of infection ,survival ,reproduction ,Microbiology ,QR1-502 - Abstract
Mayaro virus is a mosquito-borne Alphavirus endemic to forests of tropical South America with a sylvatic cycle involving non-human primates and Haemagogus mosquitoes. Human infection with Mayaro virus causes a febrile illness and long-lasting arthralgia and cases are often associated with exposure to tropical forest habitats. Human movement between tropical forest habitats and urban settings may allow for imported cases and subsequent local transmission by domestic mosquito Aedes aegypti. The relative importance of Ae. aegypti as a vector of Mayaro virus may depend on the pathogenic effects of the virus on fitness correlates, especially those entomological parameters that relate to vectorial capacity. We performed mosquito infection studies and compared adult survival and fecundity of females from Brazilian and Floridian populations of Ae. aegypti following oral ingestion of uninfectious (control) and Mayaro virus infectious blood. Mayaro virus infected and refractory mosquitoes had similar or 30–50% lower fecundity than control (unexposed) mosquitoes, suggesting a reproductive cost to mounting an immune response or phenotypic expression of refractoriness. Survival of adult female mosquitoes and targeted gene expression in the Toll and IMD pathways were not altered by Mayaro virus infection. Adult lifespan and fecundity estimates were independent of measured viral titer in the bodies of mosquitoes. The lack of adverse effects of infection status on female survival suggests that Mayaro virus will not alter vectorial capacity mediated by changes in this parameter.
- Published
- 2020
- Full Text
- View/download PDF
131. Chikungunya virus vector competency of Brazilian and Florida mosquito vectors.
- Author
-
Nildimar Alves Honório, Keenan Wiggins, Daniel Cardoso Portela Câmara, Bradley Eastmond, and Barry W Alto
- Subjects
Arctic medicine. Tropical medicine ,RC955-962 ,Public aspects of medicine ,RA1-1270 - Abstract
Chikungunya virus is a vector-borne alphavirus transmitted by the bites of infected female Ae. aegypti and Ae. albopictus. In Brazil between 2014 and 2016 almost 320 thousand autochthonous human cases were reported and in Florida numerous imported CHIKV viremic cases (> 3,800) demonstrate the potential high risk to establishment of local transmission. In the present study, we carried out a series of experiments to determine the viral dissemination and transmission rates of different Brazilian and Florida populations of Ae. aegypti and Ae. albopictus at 2, 5, and 13 days post-infection for the emergent Asian genotype of CHIKV. Our results show that all tested populations of Ae. aegypti and Ae. albopictus have a high proportion (> 0.80) of individuals with disseminated infection as early as 2 days-post exposure. We found no significant treatment effects of mosquito population origin effects on viral dissemination rates. Transmission rates had a heterogeneous pattern, with US Ae. aegypti and Brazilian Ae. albopictus having the highest proportion of individuals with successful infection (respectively 0.50 and 0.82 as early as 2 days-post infection). Model results found significant effects of population origin, population origin x species, population origin x days post-infection and population origin x species x days post infection.
- Published
- 2018
- Full Text
- View/download PDF
132. Tamta's World: The Life and Encounters of a Medieval Noblewoman from the Middle East to Mongolia
- Author
-
Eastmond, Antony
- Published
- 2017
- Full Text
- View/download PDF
133. Ethical Angles on Service Learning
- Author
-
Eastmond, Nick, Thomas, Jonathan M., Fee, Samuel B., editor, and Belland, Brian R., editor
- Published
- 2012
- Full Text
- View/download PDF
134. Capturing Carbon Dioxide from Air with Charged Sorbents
- Author
-
Huaiguang Li, Mary E. Zick, Teedhat Trisukhon, Xinyu Liu, Helen Eastmond, Shivani Sharma, Tristan Spreng, Jack Taylor, Jamie W. Gittins, Cavan Farrow, Phillip J. Milner, and Alexander C. Forse
- Abstract
There is an urgent need for improved sorbents for the capture of carbon dioxide from the atmosphere, a process known as direct air capture. In particular, low-cost materials that can be regenerated at low temperatures would overcome the limitations of current technologies. In this work, we introduce an electrochemical method for preparing designer “charged-sorbent” materials and synthesise a hydroxide-functionalised activated carbon that can rapidly capture carbon dioxide from ambient air via (bi)carbonate formation. Unlike traditional bulk carbonates, material regeneration can be achieved at low temperatures (100 ºC), and the sorbent's conductive nature permits direct Joule heating regeneration. Given their highly tailorable pore environments and low cost, we anticipate that charged-sorbents will find numerous potential applications in chemical separations, catalysis, and beyond.
- Published
- 2023
- Full Text
- View/download PDF
135. Assessment of insecticide resistance of Aedes aegypti (Diptera: Culicidae) populations to insect growth regulator pyriproxyfen, in the northeast region of Brazil
- Author
-
Kauara B. Campos, Abdullah A. Alomar, Bradley H. Eastmond, Marcos T. Obara, Luciana dos S. Dias, Rafi U. Rahman, and Barry W. Alto
- Subjects
Ecology ,Ecology, Evolution, Behavior and Systematics - Published
- 2023
- Full Text
- View/download PDF
136. A q-Analysis of Stable Daughter Nuclide
- Author
-
Eastmond, Shawn
- Abstract
In 1910, Harry Batemen studied and found the solutions for a system of ho-mogeneous first-order differential equations which are connected to chains of radioactiveisotopes. The equation would later be known as Bateman equation. Nonetheless, Bate-man analysis is usualy performed for the following cases:(i)the daughter nuclide is stable,i.e., λd = 0 assuming Nd(0) = 0, (ii) t(parent) < t(daughter), (iii) t(parent) > t(daughter), and (iv) 1/2 1/2 1/2 1/2(parent) (daughter)t1/2 ≫ t1/2 . In this paper we provide a solution to Bateman equation using quantumcalculus. In addition, we will only consider case (i) and hence, we will explore the behavior of a set of miscellaneous q-values—provided q ∈ (0, 1) or the superextensive regime—using Tsallis functions; in particular, Tsallis q-logarithm.
- Published
- 2023
- Full Text
- View/download PDF
137. Zika Virus: A Systematic Review of Teratogenesis, Congenital Anomalies, and Child Mortality
- Author
-
Sara Elena Guerrero Saldivia, Sumedha Unnikrishnan, Yeny Y Chavarria, Adebisi O Akindele, Ana P Jalkh, Aziza K Eastmond, Chaitra Shetty, Syed Muhammad Hannan Ali Rizvi, Joudi Sharaf, Kerry-Ann D Williams, Maha Tariq, Maitri V Acharekar, and Prachi Balani
- Subjects
General Engineering - Published
- 2023
- Full Text
- View/download PDF
138. Ketocarotenoid production in tomato triggers metabolic reprogramming and cellular adaptation: The quest for homeostasis?
- Author
-
Marilise Nogueira, Eugenia M. A. Enfissi, Elliott J. Price, Guillaume N. Menard, Eudri Venter, Peter J. Eastmond, Einat Bar, Efraim Lewinsohn, and Paul D. Fraser
- Abstract
SUMMARYPlants are sessile and therefore have developed an extraordinary capacity to adapt to external signals. Here, the focus is on the plasticity of the plant cell to respond to new intracellular cues. Ketocarotenoids are high-value natural red pigments with potent antioxidant activity. In the present study, system level analyses have revealed that the heterologous biosynthesis of ketocarotenoids in tomato initiated a series of cellular and metabolic mechanisms to cope with the formation of metabolites that are non-endogenous to the plant. The broad multilevel changes were linked to, among others, (i) the remodelling of the plastidial membrane, where the synthesis and storage of ketocarotenoids occurs, (ii) the recruiting of core metabolic pathways for the generation of metabolite precursors and energy, and (iii) redox control. The role of the metabolites as regulators of cellular processes shown here, reinforces their pivotal role suggested in the remodelled “central dogma” concept.
- Published
- 2023
- Full Text
- View/download PDF
139. Aneuploidy
- Author
-
David A. Eastmond
- Published
- 2023
- Full Text
- View/download PDF
140. Capturing Carbon Dioxide from Air with Charged Sorbents
- Author
-
Li, Huaiguang, primary, Zick, Mary E., additional, Trisukhon, Teedhat, additional, Liu, Xinyu, additional, Eastmond, Helen, additional, Sharma, Shivani, additional, Spreng, Tristan, additional, Taylor, Jack, additional, Gittins, Jamie W., additional, Farrow, Cavan, additional, Milner, Phillip J., additional, and Forse, Alexander C., additional
- Published
- 2023
- Full Text
- View/download PDF
141. Native Wolbachia infection and larval competition stress shape fitness and West Nile virus infection in Culex quinquefasciatus mosquitoes
- Author
-
Alomar, Abdullah A., primary, Pérez-Ramos, Daniel W., additional, Kim, Dongmin, additional, Kendziorski, Natalie L., additional, Eastmond, Bradley H., additional, Alto, Barry W., additional, and Caragata, Eric P., additional
- Published
- 2023
- Full Text
- View/download PDF
142. A q-Analysis of Stable Daughter Nuclide
- Author
-
Eastmond, Shawn, primary
- Published
- 2023
- Full Text
- View/download PDF
143. Zika Virus: A Systematic Review of Teratogenesis, Congenital Anomalies, and Child Mortality
- Author
-
Guerrero Saldivia, Sara Elena, primary, Unnikrishnan, Sumedha, additional, Chavarria, Yeny Y, additional, Akindele, Adebisi O, additional, Jalkh, Ana P, additional, Eastmond, Aziza K, additional, Shetty, Chaitra, additional, Rizvi, Syed Muhammad Hannan Ali, additional, Sharaf, Joudi, additional, Williams, Kerry-Ann D, additional, Tariq, Maha, additional, Acharekar, Maitri V, additional, and Balani, Prachi, additional
- Published
- 2023
- Full Text
- View/download PDF
144. Ketocarotenoid production in tomato triggers metabolic reprogramming and cellular adaptation: The quest for homeostasis?
- Author
-
Nogueira, Marilise, primary, Enfissi, Eugenia M. A., additional, Price, Elliott J., additional, Menard, Guillaume N., additional, Venter, Eudri, additional, Eastmond, Peter J., additional, Bar, Einat, additional, Lewinsohn, Efraim, additional, and Fraser, Paul D., additional
- Published
- 2023
- Full Text
- View/download PDF
145. Art on the Edge: The Church of the Holy Cross, Jvari, Georgia
- Author
-
Eastmond, Antony, primary
- Published
- 2023
- Full Text
- View/download PDF
146. Developing satellite-estimated precipitation monthly reports for selected locations in the Republic of the Marshall Islands
- Author
-
Senay, Gabriel B., primary, Helweg, David A., additional, Kagone, Stefanie, additional, Taylor, John B., additional, Cecere, Thomas, additional, Eastmond, Tiare, additional, Koch, Amy, additional, Nelson, Kurtis, additional, and Rufus, Lajikit, additional
- Published
- 2023
- Full Text
- View/download PDF
147. Abstract 1249: 14-3-3 binding stabilizes and sequesters PTOV1 to the cytoplasm during G1
- Author
-
Pennington, Katie, primary, McEwan, Colten, additional, Woods, James, additional, Muir, Colin, additional, Sahankumari, A.G. Pramoda, additional, Eastmond, Riley, additional, Balasooriya, Eranga, additional, Egbert, Christina, additional, and Andersen, Joshua, additional
- Published
- 2023
- Full Text
- View/download PDF
148. Burden tests can be used to map causal genes for a simple metabolic trait in an exome‐sequenced polyploid mutant population
- Author
-
Guillaume N. Menard and Peter J. Eastmond
- Subjects
Polyploidy ,Phenotype ,Burden test ,Mutant population ,Wheat ,Exome ,Plant Science ,Agronomy and Crop Science ,Rare-variant association analysis ,Biotechnology - Abstract
Forward genetic screens are an excellent tool to assign gene function, but it is often necessary to employ map-based cloning to identify the causal genes. This can be laborious and represents a bottleneck in plant fundamental and applied research. With advances in DNA technology, it is becoming increasingly affordable to sequence large populations. Krasileva et al. (2017) exome sequenced tetraploid and hexaploid wheat ethyl methanesulfonate (EMS) mutagenized populations, primarily to facilitate reverse genetic screens. Gene redundancy allows a very high mutant load of 35–40 mutations per kilobase, and the populations of ~1500 and ~1200 lines each harbour ~22–23 missense or truncation mutations per gene. Here, we show that burden tests, a simple form of rare-variant association analysis developed for human disease genetics (Lee et al., 2014), can be used to identify causal genes in the hexaploid wheat (Triticum aestivum) cv. Cadenza mutant population, without the need for map-based cloning.
- Published
- 2022
- Full Text
- View/download PDF
149. Empowering programmability for tangibles.
- Author
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Eric Rosenbaum, Evelyn Eastmond, and David Mellis
- Published
- 2010
- Full Text
- View/download PDF
150. Lymphohematopoietic cancers induced by chemicals and other agents and their implications for risk evaluation: An overview
- Author
-
Eastmond, David A., Keshava, Nagalakshmi, and Sonawane, Babasaheb
- Published
- 2014
- Full Text
- View/download PDF
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