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503 results on '"Duan, Hongxia"'

104. Rehabilitation Effects of Acupuncture on the Diaphragm Dysfunction in Chronic Obstructive Pulmonary Disease: A Systematic Review

Author

Liu,Qinxin, Duan,Hongxia, Lian,Anbei, Zhuang,Min, Zhao,Xianli, and Liu,Xiaodan

Subjects
International Journal of Chronic Obstructive Pulmonary Disease
Abstract

Qinxin Liu,1 Hongxia Duan,1 Anbei Lian,1 Min Zhuang,1,2 Xianli Zhao,1 Xiaodan Liu1,3 1School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Department of Rehabilitation, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China; 3Engineering Research Center of Intelligent Rehabilitation of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of ChinaCorrespondence: Xiaodan Liu; Xianli ZhaoSchool of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaTel +86-21-51323158Fax +86-21- 51323199Email hzhp403@126.com; zhaoxianli16@126.comIntroduction: Diaphragm dysfunction is a significant extrapulmonary effect in chronic obstructive pulmonary disease (COPD), which is manifested by changes in diaphragm structure and reduced diaphragm strength. Acupuncture is a traditional rehabilitation technique in China, which has been used in rehabilitation for COPD. But whether acupuncture can improve the diaphragm function of COPD patients remains to be verified.Objective: The objective of this study was to evaluate the rehabilitation effects of acupuncture on diaphragm dysfunction in patients with COPD.Methods: The authors retrieved in CNKI, VIP, SinoMed, PubMed, Ebsco, Web of Science, from inception to November 2020, for relevant randomized control trials. Two researchers independently screened the articles and extracted the data. The quality of the included studies was evaluated by Physiotherapy Evidence Database scale. The primary outcome measures were maximal inspiratory pressure and the scale for accessory respiratory muscle mobilization, the secondary outcome measures were pulmonary function-related indicators and arterial blood gas indicators.Results: Nine articles were finally obtained. Seven studies added acupuncture to standard treatment for patients with diaphragm dysfunction in COPD and found statistically significant changes in the maximum inspiratory pressure and the scale for accessory respiratory muscle mobilization. Two studies have proved that use acupuncture combined with other Traditional Chinese Medicine methods in the rehabilitation for COPD can effectively improve the diaphragm strength and diaphragmatic motor performance. Seven studies showed that acupuncture has obvious improvement in pulmonary ventilation function. Seven studies reported significant differences in arterial blood gas pre- to post-intervention.Conclusion: This systematic review found that acupuncture can effectively enhance the diaphragm strength, relieve respiratory muscle fatigue, it can also play a promoting role in improving lung function, hypoxia, and carbon dioxide retention, as well as preventing and alleviating respiratory failure. The generalizability of these results is limited by the design of the included studies.Keywords: chronic obstructive pulmonary disease, diaphragm, dysfunction, acupuncture, rehabilitation effect

Published
2021

106. Development of Mitomycin C-Loaded Nanoparticles Prepared Using the Micellar Assembly Driven by the Combined Effect of Hydrogen Bonding and π–π Stacking and Its Therapeutic Application in Bladder Cancer

Author

Qi, Lingling, primary, Liu, Chao, additional, Zhang, Yingying, additional, Zhang, Zheao, additional, Duan, Hongxia, additional, Zhao, Heming, additional, Xin, Xin, additional, Chen, Liqing, additional, Jin, Mingji, additional, Guan, Youyan, additional, Gao, Zhonggao, additional, and Huang, Wei, additional

Published
2021
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112. Learning on rework management of construction projects: A case study

Author

Zhang, Shang, Duan, Hongxia, Zhao, Xianbo, Xia, Bo, Feng, Yingbin, Galvin, Shane, Zhang, Shang, Duan, Hongxia, Zhao, Xianbo, Xia, Bo, Feng, Yingbin, and Galvin, Shane

Abstract

Effective rework management (RM) not only increases profitability but also enhances management competence of contractors. However, little research has been conducted to explore the learning nature of RM from the perspective of contractors. Based on a longitudinal case study of three construction projects, this paper aims to present a holistic analysis on the RM learning process from the experience of a small-to-medium (SM) general contractor (GC) in China to explore the underlying facts determining the effectiveness of RM practices. It was found that a variety of causes led to rework in the three projects, which highlighted the importance to enhance GC's learning capacity to effectively reduce rework. A conceptual RM learning framework (CRMLF), which consists of people, approach, process, tool and project environment, was developed based on the analysis of influential factors of successful learning within the RM domain. This paper is valuable for practitioners and academics to understand the inherent nature of RM to continuously improve the project performance.

Published
2021

113. PARC/CCL18 is Associated with Inflammation, Emphysema Severity and Application of Inhaled Corticosteroids in Hospitalized COPD Patients

Author

Duan,Hongxia, Liang,Long, Liu,Xinyang, Xie,Shuanshuan, Wang,Changhui, Duan,Hongxia, Liang,Long, Liu,Xinyang, Xie,Shuanshuan, and Wang,Changhui

Abstract

Hongxia Duan, Long Liang, Xinyang Liu, Shuanshuan Xie, Changhui Wang Department of Respiratory Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of ChinaCorrespondence: Shuanshuan Xie; Changhui WangDepartment of Respiratory Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, #301, Mid Yanchang Road, Shanghai, People’s Republic of ChinaTel/Fax +86-21-66301685Email xieshuanshuan@aliyun.com; wang-chang-hui@hotmail.comBackground: Pulmonary and activation-regulated chemokine (PARC) also named CC-chemokine ligand 18 (CCL18) is a lung-predominant inflammatory protein that is found in serum. The relationship of PARC/CCL18 with the chronic obstructive pulmonary disease (COPD) is not fully understood. The aim of the present study is to analyze the expression of PARC/CCL18 in COPD.Methods: Ninety-eight hospitalized COPD patients and 60 healthy volunteers from January 2019 to December 2019 were recruited in this retrospective study. Gender, age, height, weight, disease duration, smoking status, blood cell classification and count, length of hospital stay (LOS), symptom score, including COPD Assessment Test (CAT) score, modified British Medical Research Council (mMRC) score, lung function and therapy were recorded and serum PARC/CCL18 was analyzed by ELISA. The correlation between symptom score, blood cell classification and count, CRP, lung function parameters and serum levels of PARC/CCL18 and ROC curves of PARC/CCL18 levels and inhaled corticosteroids (ICS) were accessed.Results: It was found that serum PARC/CCL18 level in hospitalized COPD population was significantly higher than that in healthy people (p=0.003). COPD patients with emphysema had significantly higher serum level of PARC/CCL18 than those without emphysema (p=0.049). Total lung capacity (TLC) and residual volume (RV)/TLC had positive correlation with serum level of PARC/CCL18 (p=0.00

Published
2021

120. CD146 is a Novel ANGPTL2 Receptor that Promotes Obesity by Manipulating Lipid Metabolism and Energy Expenditure

Author

Wu, Zhenzhen, primary, Liu, Jingyu, additional, Chen, Gang, additional, Du, Junfeng, additional, Cai, Huiyun, additional, Chen, Xuehui, additional, Ye, Gaoqi, additional, Luo, Yongting, additional, Luo, Yiyi, additional, Zhang, Liwen, additional, Duan, Hongxia, additional, Liu, Zheng, additional, Yang, Sai, additional, Sun, Hongwei, additional, Cui, Yan, additional, Sun, Lei, additional, Zhang, Hongjie, additional, Shi, Guizhi, additional, Wei, Taotao, additional, Liu, Pingsheng, additional, Yan, Xiyun, additional, Feng, Jing, additional, and Bu, Pengcheng, additional

Published
2021
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125. Review and prospect of CD146 research

Author

LIU, JingYu, primary, MA, XinRan, additional, XU, QingJi, additional, YAN, XiYun, additional, XIONG, ChaoLiang, additional, FENG, Jing, additional, WANG, DaJi, additional, DUAN, HongXia, additional, XIANG, JianQuan, additional, HE, ZhiHeng, additional, and JING, Lin, additional

Published
2020
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132. Muscle metabolomics analysis reveals potential biomarkers of exercise‑dependent improvement of the diaphragm function in chronic obstructive pulmonary disease

Author

Li, Jian, primary, Lu, Yufan, additional, Li, Ning, additional, Li, Peijun, additional, Su, Jianqing, additional, Wang, Zhengrong, additional, Wang, Ting, additional, Yang, Zhaoyu, additional, Yang, Yahui, additional, Chen, Haixia, additional, Xiao, Lu, additional, Duan, Hongxia, additional, Wu, Weibing, additional, and Liu, Xiaodan, additional

Published
2020
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134. Evaluation of isokinetic muscle strength of upper limb and the relationship with pulmonary function and respiratory muscle strength in stable COPD patients

Author

Liu,Xiaodan, Li,Peijun, Wang,Zhenwei, Lu,Yufan, Li,Ning, Xiao,Lu, Duan,Hongxia, Wang,Zhengrong, Li,Jian, Shan,Chunlei, Wu,Weibing, Liu,Xiaodan, Li,Peijun, Wang,Zhenwei, Lu,Yufan, Li,Ning, Xiao,Lu, Duan,Hongxia, Wang,Zhengrong, Li,Jian, Shan,Chunlei, and Wu,Weibing

Abstract

Xiaodan Liu,1,2 Peijun Li,3 Zhenwei Wang,4 Yufan Lu,3 Ning Li,3 Lu Xiao,1 Hongxia Duan,1 Zhengrong Wang,3 Jian Li,3 Chunlei Shan,1,2 Weibing Wu3 1School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Institute of Rehabilitation Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 3Department of Sports Medicine, Shanghai University of Sport, Shanghai, People’s Republic of China; 4Department of Respiratory Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, People’s Republic of ChinaCorrespondence: Chunlei ShanSchool of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of ChinaEmail tcm4463@outlook.comWeibing WuDepartment of Sports Medicine, Shanghai University of Sport, Shanghai, People’s Republic of ChinaEmail wwb75@126.comBackground: Upper limb muscle strength plays an important role in respiratory and pulmonary function, and limited research focuses on the role of strength and endurance of the elbow extensor and flexor. This study was conducted to accurately assess upper limb muscle function and quantified associations with pulmonary function and respiratory muscle strength in patients with stable chronic obstructive pulmonary disease (COPD).Methods: In this cross-sectional study, patients with stable COPD treated in Yue-Yang Integrative Medicine Hospital from March 2014 to March 2016 were recruited. All participants underwent a pulmonary function test (forced expiratory volume in first second/forced vital capacity, FEV1/FVC; percentage value of predicted FEV1, FEV1%pred), a respiratory muscle strength test (maximal inspiratory pressure, MIP; maximal expiratory pressure, MEP), and an isokinetic test of domin

Published
2019

135. Design, synthesis and antifungal/anti‐oomycete activity of pyrazolyl oxime ethers as novel potential succinate dehydrogenase inhibitors.

Author

Wang, Minlong, Du, Ying, Ling, Chen, Yang, Zhaokai, Jiang, Biaobiao, Duan, Hongxia, An, Jie, Li, Xinghai, and Yang, Xinling

Subjects
SUCCINATE dehydrogenase, OXIMES, ANTIFUNGAL agents, ETHERS, PHYTOPHTHORA capsici, HYDROPHOBIC interactions, PLANT diseases
Abstract

BACKGROUND Succinate dehydrogenase inhibitors (SDHIs) play an increasingly important role in controlling plant diseases. However, the similar structures of SDHIs result in rapid development of cross‐resistance development and a clear bottleneck of poor activity against oomycetes, therefore the need to seek new SDHI fungicides with novel structures is urgent. RESULTS: Innovative pyrazolyl oxime ethers were designed by replacing amide with oxime ether based on the succinate dehydrogenase (SDH) structure, and 19 pairs of Z‐ and E‐isomers were efficiently prepared for the discovery of SDHI compounds with a novel bridge. Their biological activities against four fungi and two oomycetes were evaluated, and substantial differences were observed between the Z‐ and E‐ isomers of the title compounds. Furthermore, most of these compounds exhibited remarkable activities against Rhizoctonia solani with EC50 values of less than 10 mg L−1in vitro, and bioassay in vivo further confirmed that E‐I‐6 exhibited good protective efficacy (76.12%) at 200 mg L−1. In addition, Z‐I‐12 provided better activity against the oomycetes Pythium aphanidermatum and Phytophthora capsici (EC50 = 1.56 and 0.93 mg L−1) than those of boscalid. Moreover, E‐I‐12 exhibited excellent SDH inhibition (IC50 = 0.21 mg L−1) thanks to its good binding ability to the SDH by hydrogen‐bonding interactions, π‐cation interaction and hydrophobic interactions. CONCLUSION: Novel pyrazolyl oxime ethers have the potential as SDHI compounds for future development, and the strategy of replacing an amide bond with oxime ether may offer an alternative option in SDHI fungicide discovery. [ABSTRACT FROM AUTHOR]

Published
2021
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145. Synthesis, insecticidal activity and molecular docking study of clothianidin analogues with hydrazide group

Author

Qu Yanyan, Xinling Yang, Hong-Yue Li, Dan Xu, Dunlun Song, Duan Hongxia, Wei Peng, and Shao-Hua Liu

Subjects
chemistry.chemical_compound, Chemistry, Stereochemistry, Neonicotinoid, Proton NMR, Clothianidin, Bioassay, Aphis glycines, General Chemistry, Hydrazide
Abstract

A series of novel neonicotinoid analogues were designed and synthesized by introducing a hydrazide group into clothianidin. Their structures were confirmed by IR, 1 H NMR, and HRMS (ESI). Preliminary bioassay showed that some compounds, 5b and 5g , exhibited good activity against soybean aphids ( Aphis glycines ) at 100 mg L −1 . In addition, molecular docking with receptor was carried out to explain their different activity from clothianidin.

Published
2014

146. Computational-Aided Discovery of Novel 1,3-Benzodioxole Plant Growth Retardants.

Author

Wang, Jine, Yang, Zhikun, Duan, Hongxia, Duan, Liusheng, and Tan, Weiming

Subjects
PLANT growth, ROOT growth, CROP yields, ARABIDOPSIS thaliana, CRYSTAL structure
Abstract

Plant growth retardants can enhance the lodging resistance of crops and prevent yield losses. In this study, we used the crystal structure of the gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1) to aid the discovery of novel growth retardants. The Maybridge database was filtered based on multiple-screening analysis, including pharmacophore modeling, target structures, Lipinski's rules of 5, and physicochemical properties. Finally, the 1,3-benzodioxole compounds were screened and their potential interaction mechanisms, synthesis, and biological activity on the root lengths of wild-type and mutant-type Arabidopsis thaliana were investigated. The results showed that the compounds inhibited root growth in WT A. thaliana at a range of concentrations, with optimal inhibition observed at 100 μmol/L. The inhibition by compound HTS05309 was comparable to that of uniconazole (100%). Quantitative experiments confirmed that the compounds inhibited A. thaliana growth. These results suggested that novel plant growth retardants have been identified based on computational-aided discovery. [ABSTRACT FROM AUTHOR]

Published
2020
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