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Hierarchical structures are abundant in nature, such as in the superhydrophobic surfaces of lotus leaves and the structural coloration of butterfly wings. They consist of ordered features across multiple size scales, and their unique properties have attracted enormous interest in wide-ranging fields, including energy storage, nanofluidics, and nanophotonics. Femtosecond lasers, capable of inducing various material modifications, have shown promise for manufacturing tailored hierarchical structures. However, existing methods such as multiphoton lithography and 3D printing using nanoparticle-filled inks typically involve polymers and suffer from high process complexity. Here, we demonstrate 3D printing of hierarchical structures in inorganic silicon-rich glass featuring self-forming nanogratings. This approach takes advantage of our finding that femtosecond laser pulses can induce simultaneous multiphoton crosslinking and self-formation of nanogratings in hydrogen silsesquioxane (HSQ). The 3D printing process combines the 3D patterning capability of multiphoton lithography and the efficient generation of periodic structures by the self-formation of nanogratings. We 3D-printed micro-supercapacitors with large surface areas and a remarkable areal capacitance of 1 mF/cm^2 at an ultrahigh scan rate of 50 V/s, thereby demonstrating the utility of our 3D printing approach for device applications in emerging fields such as energy storage.

Medical vision-language pretraining models (VLPM) have achieved remarkable progress in fusing chest X-rays (CXR) with clinical texts, introducing image-text data binding approaches that enable zero-shot learning and downstream clinical tasks. However, the current landscape lacks the holistic integration of additional medical modalities, such as electrocardiograms (ECG). We present MEDBind (Medical Electronic patient recorD), which learns joint embeddings across CXR, ECG, and medical text. Using text data as the central anchor, MEDBind features tri-modality binding, delivering competitive performance in top-K retrieval, zero-shot, and few-shot benchmarks against established VLPM, and the ability for CXR-to-ECG zero-shot classification and retrieval. This seamless integration is achieved through combination of contrastive loss on modality-text pairs with our proposed contrastive loss function, Edge-Modality Contrastive Loss, fostering a cohesive embedding space for CXR, ECG, and text. Finally, we demonstrate that MEDBind can improve downstream tasks by directly integrating CXR and ECG embeddings into a large-language model for multimodal prompt tuning.

In the ALICE read-out and trigger system, the present GBT and CRU based solution will also serve for Run4 without major modifications. By now, the GBT protocol has been superseded by lpGBT. Extensions of the ALICE system (e.g. the planned FoCal and ITS3 detector) will therefore require to use lpGBT while keeping the compatibility with the existing system. In this paper we show the implementation and testing of a possible integration of the lpGBT-FPGA IP into the CRU firmware, allowing the extension of the present system, keeping it more versatile and future-proof., Comment: 5 pages

We present the Citizen Science program Active Asteroids and describe discoveries stemming from our ongoing project. Our NASA Partner program is hosted on the Zooniverse online platform and launched on 2021 August 31, with the goal of engaging the community in the search for active asteroids -- asteroids with comet-like tails or comae. We also set out to identify other unusual active solar system objects, such as active Centaurs, active quasi-Hilda asteroids, and Jupiter-family comets (JFCs). Active objects are rare in large part because they are difficult to identify, so we ask volunteers to assist us in searching for active bodies in our collection of millions of images of known minor planets. We produced these cutout images with our project pipeline that makes use of publicly available Dark Energy Camera (DECam) data. Since the project launch, roughly 8,300 volunteers have scrutinized some 430,000 images to great effect, which we describe in this work. In total we have identified previously unknown activity on 15 asteroids, plus one Centaur, that were thought to be asteroidal (i.e., inactive). Of the asteroids, we classify four as active quasi-Hilda asteroids, seven as JFCs, and four as active asteroids, consisting of one Main-belt comet (MBC) and three MBC candidates. We also include our findings concerning known active objects that our program facilitated, an unanticipated avenue of scientific discovery. These include discovering activity occurring during an orbital epoch for which objects were not known to be active, and the reclassification of objects based on our dynamical analyses., Comment: 35 pages, 5 figures, 3 tables

Gaussian processes (GPs) are commonly used for geospatial analysis, but they suffer from high computational complexity when dealing with massive data. For instance, the log-likelihood function required in estimating the statistical model parameters for geospatial data is a computationally intensive procedure that involves computing the inverse of a covariance matrix with size n X n, where n represents the number of geographical locations. As a result, in the literature, studies have shifted towards approximation methods to handle larger values of n effectively while maintaining high accuracy. These methods encompass a range of techniques, including low-rank and sparse approximations. Vecchia approximation is one of the most promising methods to speed up evaluating the log-likelihood function. This study presents a parallel implementation of the Vecchia approximation, utilizing batched matrix computations on contemporary GPUs. The proposed implementation relies on batched linear algebra routines to efficiently execute individual conditional distributions in the Vecchia algorithm. We rely on the KBLAS linear algebra library to perform batched linear algebra operations, reducing the time to solution compared to the state-of-the-art parallel implementation of the likelihood estimation operation in the ExaGeoStat software by up to 700X, 833X, 1380X on 32GB GV100, 80GB A100, and 80GB H100 GPUs, respectively. We also successfully manage larger problem sizes on a single NVIDIA GPU, accommodating up to 1M locations with 80GB A100 and H100 GPUs while maintaining the necessary application accuracy. We further assess the accuracy performance of the implemented algorithm, identifying the optimal settings for the Vecchia approximation algorithm to preserve accuracy on two real geospatial datasets: soil moisture data in the Mississippi Basin area and wind speed data in the Middle East.

Following the Pluto fly-by of the New Horizons spacecraft, the mission provided a unique opportunity to explore the Kuiper Belt in-situ. The possibility existed to fly-by a Kuiper Belt object (KBO) as well as to observe additional objects at distances closer than are feasible from earth-orbit facilities. However, at the time of launch no KBOs were known about that were accessible by the spacecraft. In this paper we present the results of 10 years of observations and three uniquely dedicated efforts -- two ground-based using the Subaru Suprime Camera, the Magellan MegaCam and IMACS Cameras, and one with the Hubble Space Telescope -- to find such KBOs for study. In this paper we overview the search criteria and strategies employed in our work and detail the analysis efforts to locate and track faint objects in the galactic plane. We also present a summary of all of the KBOs that were discovered as part of our efforts and how spacecraft targetability was assessed, including a detailed description of our astrometric analysis which included development of an extensive secondary calibration network. Overall, these efforts resulted in the discovery of 89 KBOs including 11 which became objects for distant observation by New Horizons and (486958) Arrokoth which became the first post-Pluto fly-by destination., Comment: Accepted to PSJ. 40 pages, 10 figures, 10 tables

We use the Survey of Thermodynamic Processes and First and Second Laws-Long (STPFaSL-Long), a research-based survey instrument with 78 items at the level of introductory physics, to investigate introductory and advanced students' difficulties with internal energy, work, and heat transfer. We present analysis of data from 12 different introductory and advanced physics classes at four different higher education public institutions in the US in which the survey was administered in person to more than 1000 students. We find that not only introductory but also advanced physics students have many common difficulties with these introductory thermodynamic concepts after traditional lecture-based instruction in relevant concepts. We utilize a wide variety of problem types and contexts and our sample includes large numbers of introductory algebra-based, calculus-based, and advanced students. Some of our findings are consistent with prior research in this area, but others expand upon them and reveal previously unreported aspects of students' thinking. Findings related to common difficulties of students before and after traditional lecture-based instruction in college physics courses can help instructors of these courses plan instruction and curricula to improve student understanding. These findings can also be valuable for developing effective research-based curricula and pedagogies to address student difficulties and help students develop a functional understanding of these fundamental thermodynamic concepts., Comment: 23 pages, 7 figures, 5 tables

Affine cluster varieties are covered up to codimension 2 by open algebraic tori. We put forth a general conjecture (based on earlier conversation between Vivek Shende and the last author) characterizing their deep locus, i.e. the complement of all cluster charts, as the locus of points with non-trivial stabilizer under the action of cluster automorphisms. We use the diagrammatics of Demazure weaves to verify the conjecture for skew-symmetric cluster varieties of finite cluster type with arbitrary choice of frozens and for the top open positroid strata of Grassmannians $\mathrm{Gr}(2,n)$ and $\mathrm{Gr}(3,n)$. We illustrate how this already has applications in symplectic topology and mirror symmetry, by proving that the Fukaya category of Grassmannians $\mathrm{Gr}(2,2n+1)$ is split-generated by finitely many Lagrangian tori, and homological mirror symmetry holds with a Landau--Ginzburg model proposed by Rietsch. Finally, we study the geometry of the deep locus, and find that it can be singular and have several irreducible components of different dimensions, but they all are again cluster varieties in our examples in really full rank cases., Comment: v2 corrects a couple mistakes regarding the T-stabilizer locus in general braid varieties. Comments welcome!

The tentative identification of approximately ten relativistic anti-helium cosmic-ray events at AMS-02 would, if confirmed, challenge our understanding of the astrophysical synthesis of heavy anti-nuclei. We propose a novel scenario for the enhanced production of such anti-nuclei that is triggered by isolated, catastrophic injections of large quantities of energetic Standard Model (SM) anti-quarks in our galaxy by physics beyond the Standard Model (BSM). We demonstrate that SM anti-nucleosynthetic processes that occur in the resulting rapidly expanding, thermalized fireballs of SM plasma can, for a reasonable range of parameters, produce the reported tentative $\sim 2:1$ ratio of anti-helium-3 to anti-helium-4 events at AMS-02, as well as their relativistic boosts. Moreover, we show that this can be achieved without violating anti-deuterium or anti-proton flux constraints for the appropriate anti-helium fluxes. A plausible BSM paradigm for the catastrophic injections is the collision of macroscopic composite dark-matter objects carrying large net anti-baryon number. Such a scenario would require these objects to be cosmologically stable, but to destabilize upon collision, promptly releasing a fraction of their mass energy into SM anti-particles within a tiny volume. We show that, in principle, the injection rate needed to attain the necessary anti-helium fluxes and the energetic conditions required to seed the fireballs appear possible to obtain in such a paradigm. We leave open the question of constructing a BSM particle physics model to realize this, but we suggest two concrete scenarios as promising targets for further investigation., Comment: 42 pages, 10 figures, journal version

Introduction: Lung cancer is a leading cause of cancer-related mortality, and stereotactic body radiotherapy (SBRT) has become a standard treatment for early-stage lung cancer. However, the heterogeneous response to radiation at the tumor level poses challenges. Currently, standardized dosage regimens lack adaptation based on individual patient or tumor characteristics. Thus, we explore the potential of delta radiomics from on-treatment magnetic resonance (MR) imaging to track radiation dose response, inform personalized radiotherapy dosing, and predict outcomes. Methods: A retrospective study of 47 MR-guided lung SBRT treatments for 39 patients was conducted. Radiomic features were extracted using Pyradiomics, and stability was evaluated temporally and spatially. Delta radiomics were correlated with radiation dose delivery and assessed for associations with tumor control and survival with Cox regressions. Results: Among 107 features, 49 demonstrated temporal stability, and 57 showed spatial stability. Fifteen stable and non-collinear features were analyzed. Median Skewness and surface to volume ratio decreased with radiation dose fraction delivery, while coarseness and 90th percentile values increased. Skewness had the largest relative median absolute changes (22%-45%) per fraction from baseline and was associated with locoregional failure (p=0.012) by analysis of covariance. Skewness, Elongation, and Flatness were significantly associated with local recurrence-free survival, while tumor diameter and volume were not. Conclusions: Our study establishes the feasibility and stability of delta radiomics analysis for MR-guided lung SBRT. Findings suggest that MR delta radiomics can capture short-term radiographic manifestations of intra-tumoral radiation effect.

Sabidussi's theorem [Duke Math. J. 28, 1961] gives necessary and sufficient conditions under which the automorphism group of a lexicographic product of two graphs is a wreath product of the respective automorphism groups. We prove a quantum version of Sabidussi's theorem for finite graphs, with the automorphism groups replaced by quantum automorphism groups and the wreath product replaced by the free wreath product of quantum groups. This extends the result of Chassaniol [J. Algebra 456, 2016], who proved it for regular graphs. Moreover, we apply our result to lexicographic products of quantum vertex transitive graphs, determining their quantum automorphism groups even when Sabidussi's conditions do not apply., Comment: 21 pages, 2 figures. Minor changes, mostly improvements to the exposition

We discuss guidelines for evaluating the performance of parameterized stochastic solvers for optimization problems, with particular attention to systems that employ novel hardware, such as digital quantum processors running variational algorithms, analog processors performing quantum annealing, or coherent Ising Machines. We illustrate through an example a benchmarking procedure grounded in the statistical analysis of the expectation of a given performance metric measured in a test environment. In particular, we discuss the necessity and cost of setting parameters that affect the algorithm's performance. The optimal value of these parameters could vary significantly between instances of the same target problem. We present an open-source software package that facilitates the design, evaluation, and visualization of practical parameter tuning strategies for complex use of the heterogeneous components of the solver. We examine in detail an example using parallel tempering and a simulator of a photonic Coherent Ising Machine computing and display the scoring of an illustrative baseline family of parameter-setting strategies that feature an exploration-exploitation trade-off., Comment: 13 pages, 6 figures

High-quality Extragalactic Legacy-field Monitoring (HELM) is a long-term observing program that photometrically monitors several well-studied extragalactic legacy fields with the Dark Energy Camera (DECam) imager on the CTIO 4m Blanco telescope. Since Feb 2019, HELM has been monitoring regions within COSMOS, XMM-LSS, CDF-S, S-CVZ, ELAIS-S1, and SDSS Stripe 82 with few-day cadences in the $(u)gri(z)$ bands, over a collective sky area of $\sim 38$ deg${\rm ^2}$. The main science goal of HELM is to provide high-quality optical light curves for a large sample of active galactic nuclei (AGNs), and to build decades-long time baselines when combining past and future optical light curves in these legacy fields. These optical images and light curves will facilitate the measurements of AGN reverberation mapping lags, as well as studies of AGN variability and its dependences on accretion properties. In addition, the time-resolved and coadded DECam photometry will enable a broad range of science applications from galaxy evolution to time-domain science. We describe the design and implementation of the program and present the first data release that includes source catalogs and the first $\sim 3.5$ years of light curves during 2019A--2022A., Comment: 11 pages, 8 figures, 4 tables, submitted to ApJS. Median source catalogs and light curves of individual objects are publicly available at https://ariel.astro.illinois.edu/helm/

Nanoflares are thought to be one of the prime candidates that can heat the solar corona to its multi-million kelvin temperature. Individual nanoflares are difficult to detect with the present generation instruments, however their presence can be inferred by comparing simulated nanoflare-heated plasma emissions with the observed emission. Using HYDRAD coronal loop simulations, we model the emission from an X-ray bright point (XBP) observed by the Marshall Grazing Incidence X-ray Spectrometer (MaGIXS), along with nearest-available observations from the Atmospheric Imaging Assembly (AIA) onboard Solar Dynamics Observatory (SDO) and X-Ray Telescope (XRT) onboard Hinode observatory. The length and magnetic field strength of the coronal loops are derived from the linear-force-free extrapolation of the observed photospheric magnetogram by Helioseismic and Magnetic Imager (HMI) onboard SDO. Each loop is assumed to be heated by random nanoflares, whose magnitude and frequency are determined by the loop length and magnetic field strength. The simulation results are then compared and matched against the measured intensity from AIA, XRT, and MaGIXS. Our model results indicate the observed emissions from the XBP under study could be well matched by a distribution of nanoflares with average delay times 1500 s to 3000 s, which suggest that the heating is dominated by high-frequency events. Further, we demonstrate the high sensitivity of MaGIXS and XRT to diagnose the heating frequency using this method, while AIA passbands are found to be the least sensitive., Comment: Accepted for publication in the Astrophysical Journal (ApJ)

The Galileo spacecraft had distant encounters with Earth in 1990 and 1992. Limited Solid State Imager (SSI) data acquired during these encounters has been previously presented, but the majority of the data from these Earth flybys have not been presented in the literature. Observations of Earth taken from afar are both rare and directly relevant to the development of any future exo-Earth direct imaging mission. Here we present a pipeline that vets, calibrates, and measures the disk-integrated brightness of the Earth, in multiple filters, from the complete SSI data sets from both the 1990 and 1992 Galileo flybys. The result is over 1500 usable photometric measurements for Earth as an analog for an exoplanet. The 1990 data set includes full rotational lightcurves in six bandpasses spanning the optical range. The 1992 data set is more limited, with lightcurves only spanning 14 hr. Time-averaged photometry for both encounters is presented while variability and color are discussed relative to findings from NASA's EPOXI mission (which also provided photometric lighturves for Earth). The new Galileo/SSI data are used to further validate the Virtual Planetary Laboratory 3D spectral Earth model, which often serves as a stand-in for true disk-integrated observations of our planet. The revived Galileo/SSI data for Earth is a testament to the ability of NASA's Planetary Data System to maintain data over decades-long timescales. The disk-integrated products derived from these data add to a very short list of calibrated and published whole-disk observations of the Pale Blue Dot.

The Coherent Ising Machine (CIM) is a non-conventional architecture that takes inspiration from physical annealing processes to solve Ising problems heuristically. Its dynamics are naturally continuous and described by a set of ordinary differential equations that have been proven to be useful for the optimization of continuous variables non-convex quadratic optimization problems. The dynamics of such Continuous Variable CIMs (CV-CIM) encourage optimization via optical pulses whose amplitudes are determined by the negative gradient of the objective; however, standard gradient descent is known to be trapped by local minima and hampered by poor problem conditioning. In this work, we propose to modify the CV-CIM dynamics using more sophisticated pulse injections based on tried-and-true optimization techniques such as momentum and Adam. Through numerical experiments, we show that the momentum and Adam updates can significantly speed up the CV-CIM's convergence and improve sample diversity over the original CV-CIM dynamics. We also find that the Adam-CV-CIM's performance is more stable as a function of feedback strength, especially on poorly conditioned instances, resulting in an algorithm that is more robust, reliable, and easily tunable. More broadly, we identify the CIM dynamical framework as a fertile opportunity for exploring the intersection of classical optimization and modern analog computing.

Conventional heterodyne readout schemes are now under reconsideration due to the realization of techniques to evade its inherent 3 dB signal-to-noise penalty. The application of high-frequency, spectrally entangled, two-mode squeezed states can further improve the readout sensitivity of audio-band signals. In this paper, we experimentally demonstrate quantum-enhanced heterodyne readout of two spatially distinct interferometers with direct optical signal combination, circumventing the 3 dB heterodyne signal-to-noise penalty. Applying a high-frequency, spectrally entangled, two-mode squeezed state, we show further signal-to-noise improvement of an injected audio band signal of 3.5 dB. This technique is applicable for quantum-limited high-precision experiments, with application to searches for quantum gravity, gravitational wave detection and wavelength-multiplexed quantum communication., Comment: 7 pages, 3 figures, 2 table

Motivated by our recent findings in [Phys. Rev. Lett. 128, 013902, 2022], which introduces a new class of electromagnetic bulk materials whose response is similar to conventional semiconductor transistors, here we propose a one-dimensional (1D) version of such a material based on transmission lines coupled with FET isolators. We demonstrate that the response of this 1D system is nonreciprocal and non-Hermitian, analogous to the idealized transistor-metamaterial, and is also characterized by a broken time-reversal symmetry. We analyze the wave propagation in the system and find that the interaction between the eigenmodes can either lead to gain or loss depending on the propagation distance. Furthermore, it is also shown that the system may be operated at an exceptional point, wherein the response of the structure is singular, and the power gain is maximized. Finally, we demonstrate that the exceptional point coincides with the point of operation of typical microwave amplifiers, such as the distributed amplifier.

Monte Carlo integration is fundamental in scientific and statistical computation, but requires reliable samples from the target distribution, which poses a substantial challenge in the case of multi-modal distributions. Existing methods often involve time-consuming tuning, and typically lack tailored estimators for efficient use of the samples. This paper adapts the Warp-U transformation [Wang et al., 2022] to form multi-modal sampling strategy called Warp-U sampling. It constructs a stochastic map to transport a multi-modal density into a uni-modal one, and subsequently inverts the transport but with new stochasticity injected. For efficient use of the samples for normalising constant estimation, we propose (i) an unbiased estimation scheme based coupled chains, where the Warp-U sampling is used to reduce the coupling time; and (ii) a stochastic Warp-U bridge sampling estimator, which improves its deterministic counterpart given in Wang et al. [2022]. Our overall approach requires less tuning and is easier to apply than common alternatives. Theoretically, we establish the ergodicity of our sampling algorithm and that our stochastic Warp-U bridge sampling estimator has greater (asymptotic) precision per CPU second compared to the Warp-U bridge estimator of Wang et al. [2022] under practical conditions. The advantages and current limitations of our approach are demonstrated through simulation studies and an application to exoplanet detection.