Search

Objetivo. Comparar la concordancia diagnóstica del síndrome metabólico, según los criterios de diagnóstico de la Federación Internacional de Diabetes (FID) y del Programa Nacional de Educación sobre el Colesterol (PNEC-ATP III) en una población adulta que habita a 3,270 m s.n.m. Métodos. Se diseñó un estudio observacional, transversal y analítico. La muestra se determinó con criterios de inclusión y exclusión, de forma aleatoria simple. Se realizaron los análisis de laboratorio en ayunas. Se utilizó el coeficiente kappa (k) para determinar el grado de concordancia. Resultados. Se incluyeron 43 (100 %) personas. El 58,1 % era mayor de 60 años. La frecuencia del Síndrome Metabólico fue del 27,9 % (12), según los criterios de la FID y del 20,9 % (9), según los criterios del PNEC-ATP III. La frecuencia de síndrome metabólico se incrementó con el aumento de la edad, especialmente a partir de los 50 años y es más común en mujeres con sobrepeso. Entre ambos criterios de diagnóstico se encontró una valoración del coeficiente de kappa de 0,812. Conclusión. Existe una alta concordancia entre los criterios de diagnóstico que utilizan las guías de la FID y del PNEC-ATP III para realizar el diagnóstico de síndrome metabólico en pobladores que viven en la altura.

La fibra alimentaria tiene muchos efectos positivos en la salud. Esta publicación describe las relaciones entre la fibra alimentaria y la prevención y el tratamiento de enfermedades crónicas. This new 2-page publication of the UF/IFAS Food Science and Human Nutrition Department is a Spanish translation of FSHN18-11/FS314, Dietary Fiber and Chronic Disease. Written by Wendy Dahl and translated by Daniela Rivero Mendoza. https://edis.ifas.ufl.edu/fs322

Las transformaciones surgidas durante los procesos de limpieza de los alimentos grasos para determinar productos de oxidación de colesterol (COP) limitan los resultados reales en un estudio. Por tanto, el objetivo de este estudio fue comparar los COP obtenidos por distintos métodos de extracción: fase sólida (SPE) y cromatografía líquida en fase normal y reversa, comparando sus perfiles de elución. Adicionalmente, se tuvo como objetivo optimizar los procesos de limpieza para reducir las transformaciones de COP. Se usaron muestras de lomo de cerdo crudo, jamón serrano y salmón ahumado. Las transformaciones de COP se determinaron por SPE y GC–FID y se optimizaron los métodos de limpieza con la técnica SPE. Los cartuchos apolares no mostraron transformación de COP durante el tratamiento de muestras y los cambios de pH generaron transformaciones del triol a 6 ceto epóxido. Debido a que la limpieza del cartucho suele ser deficiente y genera coelución de compuestos indeseables (ácidos grasos) implicados en la transformación de epóxidos α y β en triol, estas transformaciones se evitaron con la técnica SPE, uso de cartuchos C18, con ajuste del volumen de elución de MeOH y ajustes del pH. La reducción de los pasos de la limpieza de muestras optimizó el proceso en un 73%.

Introducción: La yuca es un tubérculo originario de Brasil perteneciente a la familia Euphorbiacea y al género Manihot, a partir de la cual se produce el casabe. Hoy día el casabe forma parte de la dieta de los venezolanos, siendo valorado por su contenido calórico y riqueza en fibra dietética (FD). En este estudio se evaluó el efecto del consumo de dietas que contenían fibra dietética proveniente de diferentes variedades de casabe, sobre la concentración de lípidos séricos en un modelo experimental. Métodos: se utilizaron 20 ratas machos adultas, cepa Sprague Dawley, divididas en 4 grupos: un control sin fibra y tres grupos experimentales en los que se sustituyó el almidón de maíz por una variedad de casabe, identificados por su procedencia como: “Casabe Miranda”, “Casabe Sucre” y “Casabe Amazonas”. Resultados: El contenido de FD total y su fracción soluble fueron significativamente mayores en las variedades de casabe Amazonas y Sucre (p

Objetivo. Determinar la frecuencia y características de una población de pacientes obesos con y sin riesgo cardiometabólico (RCM) y revisar el concepto de obeso cardiometabólico normal (OCMN). Materiales y Métodos. Estudio analítico, transversal, de 105 pacientes obesos, de 30 a 75 años, de ambos géneros. Recolectados de un programa preventivo promocional de mayo de 2015 a abril del año 2016. Previo consentimiento informado, se registró la edad, género, medidas antropométricas, presión arterial (PA), antecedentes personales y familiares de factores de riesgo cardiovascular (FRCV). En ayunas, se determinó en sangre glucosa (G), colesterol total (CT), colesterol HDL, triglicéridos (Tg), creatinina, proteínas plasmáticas, bilirrubinas, transaminasas (AST,ALT), fosfatasa alcalina (FA) y gamaglutamiltranspeptidasa (GGTP), por métodos convencionales; las fracciones VLDL, LDL y NoHDL fueron calculados. Se empleó el programa SPSS.23 para el análisis estadístico Resultados. El 77,4% fueron mujeres, edad promedio 51±0,86 años. El 45,7% tuvo obesidad grado I, 24,7% grado II y 29,5% grado III. Las mujeres tuvieron menor talla, peso y circunferencia abdominal (CA) y cifras más altas de HDL que los varones, no hubo diferencias en otros parámetros. El 89,2 % de mujeres y 87% de varones tuvieron dislipoproteinemia; hipertensión arterial (HTA): mujeres 20,7% y varones 21,4%; tabaquismo: mujeres 5,5% y varones 42,3%; hiperglicemia: mujeres 14,2% y varones 14,2%; macrosomía/bajo peso al nacer: mujeres 6,9%, varones 0; enzimas hepáticas elevadas: mujeres 29,8%, varones 32,1%. El 9,5% fueron OCMN por tener PA, G, cHDL, Tg, cLDL cNoHDL normales. Conclusiones: La mayoría de los pacientes obesos tuvieron RCM, solo 10 (9,5%) fueron OCMN.

Objetivo: Investigar a relação entre concentração de zinco e risco cardiovascular em pacientes com insuficiência renal crônica em hemodiálise. Métodos: Estudo analítico, retrospectivo e transversal, realizado em Fortaleza, Ceará, em 2012, do qual participaram 43 adultos com insuficiência renal crônica em hemodiálise (grupo HD) e 35 saudáveis (CO - controle). Coletaram-se dados socioeconômicos e bioquímicos (colesterol total - CT, lipoproteína de baixa densidade - LDL, lipoproteína de muito baixa densidade - VLDL, lipoproteína de alta densidade - HDL e triglicerídeos - TG); determinou-se zinco plasmático por espectrometria de emissão óptica com plasma acoplado; coletou-se perfil lipídico do grupo HD do prontuário e do grupo CO por meio de kit Bioclin®. Obteve-se colesterol não-HDL pela fórmula: não-HDL = CT – HDL-c. Calculou-se risco cardiovascular pela razão TG/HDL, considerando risco quando >3,8. Análises por meio de testes t de Student, Pearson ou Spearman. Resultados: O zinco do grupo HD encontrou-se abaixo da referência e menor (p

Objetivo: determinar si los niveles de colesterol total predicen recuperación en actividades básicas de la vida diaria. Métodos: estudio de cohorte prospectiva que incluyó 806 pacientes ≥ 60 años, hospitalizados en la unidad geriátrica de agudos entre julio de 2013 y agosto de 2015. El desenlace fue desarrollo de discapacidad evaluada mediante el índice de Barthel ≤ 60 en cuatro momentos: 15 días antes del ingreso, al ingreso, al egreso y 30 días después. El colesterol total fue dividido en cuartiles. Se incluyeron variables demográficas, sociales y clínicas. Se usaron los modelos de regresión logística multivariada para predecir discapacidad y mortalidad, junto con el procedimiento Glimmix para análisis longitudinales y para la predicción del índice de Barthel total. Resultados: la edad fue 82,3 ± 7,2. El 52% eran mujeres. En el análisis multivariado la discapacidad estuvo asociada con edad ≥ 85 años, alta comorbilidad, deterioro social, hipoalbuminemia, MMSE 15 días, hipoalbuminemia, MMSE

În acest studiu au fost evaluate particularităţile clinice, paraclinice şi evolutive ale obezității la pacienţii cu cardiopatie ischemică. Analiza rezultatelor obţinute a relevat prezența nivelurilor ridicate de colesterol total și de lipoproteine aterogene la persoanele cu grade de obezitate marcată. Având în vedere prevalența ridicată a bolilor cardio-vasculare și a morbidității și mortalității asociate, prevenirea evenimentelor recurente la pacienții cu boală cardio-vasculară stabilită reprezintă un obiectiv major de sănătate publică. Un principiu fundamental al medicinii preventive este de a iniția măsuri adecvate pentru persoanele din grupul de risc [1].

Copyright of Revista Argentina de Cardiología is the property of Sociedad Argentina de Cardiologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: The main aim of present study was to prepare and characterize liposomal formulation of baclofen to improve the effectiveness of the topically applied formulation. Method: For the preparation of liposomes, different ratio of lecithin, cholesterol and ethanol were taken but ratio of drug and stearic acid were kept constant and prepared by ethanol injection method. Liposomes were characterized for vesicle size, vesicle shape, entrapment efficiency, in vitro studies, stability studies and in vivo studies. Results: The average particle size of formulated liposome was in the range of 3.98±0.45-4.24±0.65 μm and small unilamellar vesicles with spherical in shape observed. Entrapment efficiency of optimized formulation was 58.67±0.81 %. The maximum % cumulative drug release behaviours were 67.66±5.32 % after 10 h. formulation stored in 4±2 °C temperature shows better stability (64.19±0.26) compared to elevated temperature. Swiss albino mice were used for the in vivo study and exhibit muscle relaxant activity in terms of no. of falls from rota rod apparatus (p value =0.001). Conclusions: Baclofen loaded liposomal formulation have shown skeletal muscle relaxant activity in mice suggesting delivery of baclofen from liposomes in the therapeutic range. [ABSTRACT FROM AUTHOR]

Obesity is considered one of the biggest public health problems in the world, and responsible for increasing the development of Noncommunicable Chronic Diseases (NCDs) and by increased morbidity / mortality. Studies have shown positive effects on nutritional parameters of overweight patients after using low carb diet (LCD) and very low carb diet (VLCD). Objective was to evaluate in the scientific literature the effects of low carb diets on nutritional parameters in overweight individuals. This is a systematic review of the scientific literature search the databases Scielo, Portal Periodicals Capes, PubMed and Science Direct. The publications of the last 10 years and studies of the randomized or nonrandomized clinical trial with adults and elderly, of both sexes under the intervention of LCD or VLCD and / or associations were considered. For this purpose, 11 articles were evaluated, with 937 patients in total, aged 18 to 70 years and BMI ≥ 25 to 40 kg / m2, with intervention time from 12 weeks to 2 years, highlighting positive effects on anthropometry, body composition, blood pressure, glycemic, inflammatory and lipid profile. Thus, low carb diets have been shown to be effective in improving the health conditions of overweight individuals. [ABSTRACT FROM AUTHOR]

Copyright of Consensus (16803817) is the property of Universidad Femenina del Sagrado Corazon and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Gaceta Médica de Caracas is the property of Academia Nacional de Medicina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archivos Latinoamericanos de Nutrición is the property of Sociedad Latinoamericana de Nutricion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Overweight and obesity are pathologies that are increasing every day. This study was aimed to determine the relationship between anthropometric variables and lipid profiles in a sample of young university students, which leads to taking future prevention actions. Materials and Methods: A descriptive correlational study was conducted with a sample of 182 university students (88 women and 94 men), whose anthropometric variables and lipid profiles were evaluated. Data were analyzed using the SPSS Statistics 20 software. The sample distribution was analyzed using the Kolmogorov-Smirnov normality test. Results were expressed as mean ± standard deviation or percentage, as applicable. Significance was established under the Pearson’s correlation coefficient with p ≤0.05 value. Partial correlations were used to evaluate the relationship between each of the anthropometric risk indices and lipid profile values. Results: 46.7% of the population were overweight classifies as low-risk for waist circumference (45.1%), finding that the body adiposity index was healthy for their age in 64.5% of the participants. As for lipid profile, normal values for triglycerides were found in 60.4% of the participants and optimal values for total cholesterol in 56%. Correlational analysis with a significance of p≤0.005 was positive for gender with anthropometric variables such as Body Mass Index and waist circumference. Discussion: Anthropometric characteristics are closely related to the lipid profile behavior, as shown in this study, and the different research studies conducted with university students. Conclusions: Anthropometric variables are positively related to the gender of university students, finding an association between total cholesterol and triglycerides, which indicates a health risk factor [ABSTRACT FROM AUTHOR]

Copyright of Revista Española de Cardiología (18855857) is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Introduction: dietary fat has been reported as one of the significant risk factors in the development of cardiovascular diseases (CVD). Objective: this study aimed at assessing the possible association between fat intake and CVD. Methods: the present case-control study was conducted in the center of coronary angiography. Three-hundred and ninety nine patients who referred for elective coronary angiography with clinical suspicion of coronary artery disease were enrolled. Dietary data were collected from each patient using an interview-based food frequency questionnaire. Results: the findings of the present study revealed no significant differences between cases and controls regarding the intake of all types of fat either before or after energy adjustment. For both cases and controls the percentage of fat intake from total energy and the intakes of polyunsaturated and monounsaturated fats, cholesterol, omega-6 and omega-3 were within the recommended amounts. The intake of all fat types (except trans-fat) was not associated with the risk of developing CVD. Trans-fat intake in the second and third quartile increased the risk of CVD by OR 1.86 (95% CI: 1.03-3.34) and 2.01 (95% CI: 1.12-3.60), respectively. Conclusions: while trans-fats may be significantly associated with the development of CVD in the first two quartiles, no association has been detected with other fat types. [ABSTRACT FROM AUTHOR]

Introduction: Dyslipidemias associated to obesity constitute risk factors of several diseases specially from the cardiovascular system. Objective: To determine the prevalence of dyslipidemias in obese patients Methods: A correlational restrospective and cross-sectional study of 150 obese patients, who visited the outpatients department of Medina Clinic from Hospital Básico in Guayaquil, from 2018 to 2019. Variables used were age, sex, body mass index and laboratory results such as total cholesterol, triglycerids. LDL colesterol and mixed dyslipidemias (cholesterol HDL and VLDL). Results: In the serie, male sex (62.6 %), patients over 65 years (42.0 %), levels between critical and high risk (66 patients) prevailed, 16.0 % were classified as high risk patients with cholesterol level over 240 mg/dL. Sixty two patients showed subnormal results regarding triglycerids, in a rank higher than 150 with high limits and levels. Conclusions: A correspondance between dyslipidemias and obesity was observed, as all patients presented some type of change in lipids. [ABSTRACT FROM AUTHOR]

In order to evaluate the effect of moringa (Moringa oleifera) forage meal intake cv. Supergenius on blood indicators of colostomized broilers, a total of 24 animals (hybrids EB34), of 47 d age, were used. The birds were distributed in three treatments and eight repetitions, according to completely randomized design. The treatments consisted in a control diet (soybean- maize) and the inclusion of 10 and 20 % of moringa forage meal. Hematocrit, total proteins, albumin and total cholesterol were determined. The hematological values did not showed significant differences between treatments and remained in the physiological range for the species. Total cholesterol decreased (P <0.05) with respect to the control diet. It is concluded that the intake of moringa forage meal did not change the blood indicators of protein profile in the diet of colostomized broilers. However, total cholesterol levels decreased, which is beneficial to the birds' health. [ABSTRACT FROM AUTHOR]

Bixin is the main carotenoid present in annatto seed (Bixa orellana). The aim of this study was to evaluate the inclusion of increasing levels of bixin in the broiler diets and their effects on growth performance and meat characteristics. A total of 750 one-day-old Cobb 500 chicks were distributed in a completely randomized design with five treatments, with six replications of twenty-five birds each. Treatments consisted in different levels of bixin in diets (0.0, 0.05, 0.10, 0.15%). Were evaluated the parameters of growth performance (weight gain-WG, feed intake-FI, feed conversion ratio-FCR, productive efficiency index-PEI and viability), meat quality (pH, color, drip loss, cooking loss-CL and shear force-SF), cholesterol levels and meat oxidation. The inclusion of 0.25% of bixin resulted in negative effect on WG and PEI. The values of b * (intensity of yellow) increased linearly with the inclusion of bixin. The addition of 0.10% bixin in diet reduced the cooking loss and the addition of 0.15% reduced the shear force. The inclusion of 0.25% of bixin in diet had an antioxidant effect on breast and thigh meat, 10 days after cooking. The addition of bixin in broilers diet did not affect performance and had positive effects on meat quality, in parameters that directly affect the consumer's purchase decision. [ABSTRACT FROM AUTHOR]

Copyright of Jornal Brasileiro de Patologia e Medicina Laboratorial is the property of Sociedade Brasileira de Patologia Clinica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This is the second article in the series that aims to break the paradigms related to the alleged harm caused by saturated fats and cholesterol to health. These substances are actually present in human biochemistry and physiology, a fact that makes them essential for homeostasis. In case of ingestion deficit, they are produced endogenously, as they participate in numerous organic reactions, including structuring, fluidity and permeabilization of cell membranes, brain plasticity, nerve protection and communication, hormone formation, bile acid synthesis, and vitamin transport. It also prevents the onset of neurodegenerative diseases, psychiatric disorders, anxiety, depression and suicidal tendencies. The assumption that saturated fats and cholesterol are harmful to health, therefore, is unfounded, which requires understanding their real importance. Scientifically, it is proven that its deficit causes metabolic deficiencies and homeostatic imbalance, significantly compromising health and well-being. [ABSTRACT FROM AUTHOR]

Background: Metabolic syndrome is a cluster of metabolic abnormalities and abdominal obesity; its pathophysiologic basis, insulin resistance, has been shown to act as agent in thyroid cell proliferation. Few studies analyze the relationship between metabolic syndrome and thyroid nodular disease, with a substantial knowledge gap. Objective: Determine the association between metabolic syndrome and nodular thyroid disease in a region with adequate iodine intake. Methods: Case-control study. A total of 182 patients referred to radiology to undergo thyroid ultrasonography due to suspicion of thyroid disease. Cases had at least one thyroid nodule greater than 3 mm (n= 91). Controls did not have evidence of thyroid nodules (n= 91). Results: Bivariate analysis showed a significant association between metabolic syndrome and the presence of thyroid nodule (OR 2.56, 95% CI: 1.41-4.66, p <0.05). Low levels of HDL (OR 2.81, 95% CI: 1.54-5.12, p <0.05) and impaired fasting glucose (OR 2.05, 95%CI 1.10 to 3.78, p <0.05) were significantly associated with the presence of thyroid nodule, independent of the presence of metabolic syndrome. Multivariate analysis maintained the association between metabolic syndrome and thyroid nodule with an OR of 2.96 (95%CI 1.47 to 5.95, p <0.05); similarly, the associations of low levels of HDL (OR 2.77, 95% CI 1.44 to 5.3, p <0.05) and impaired fasting glucose (OR 2.23, 95%CI 1.14 to 4.34, p<0.05) with thyroid nodule remained significant. Conclusion: The thyroid nodular disease is associated with increased risk of metabolic syndrome, specifically decreased HDL and impaired fasting glucose levels were the factors that increased association was found. [ABSTRACT FROM AUTHOR]

Antecedentes: la interacción entre espermatozoide y el plasma seminal promueve cambios en la membrana espermática que implican una redistribución de lípidos a través de procesos bioquímicos y fisiológicos. Dado que el colesterol es el responsable de la fluidez de la membrana espermática, hay una estrecha relación entre el colesterol y factores como la capacitación y la viabilidad espermática en procesos de criopreservación. Objetivo: determinar la relación entre los niveles de colesterol y parámetros de la calidad seminal en espermatozoides de toros Chino Santandereano. Métodos: la investigación se desarrolló en el Laboratorio de Biotecnología Reproductiva Animal del Instituto Universitario de la Paz-UNIPAZ en Barrancabermeja (Santander) siguiendo el método observacional de las variables movilidad (Mg), movilidad progresiva (Mp), vitalidad (Vt), espermatozoides funcionalmente competentes (EFC) y los niveles de colesterol espermático en 30 eyaculados de 10 toros en iguales condiciones de manejo nutricional y sanitario. La valoración de la movilidad espermática (general y progresiva), la vitalidad y los EFC se realizó mediante el sistema computarizado de análisis seminal (CASA). Los niveles de colesterol se determinaron mediante espectrofotometría semiautomatizada. La evaluación de la normalidad y la homocedasticidad de datos sugirieron la utilización de estadística no paramétrica. Resultados: la prueba de Pearson evidenció una correlación significativa entre las cantidades de colesterol y el EFC (r = -0,473; p < 0,01) y el colesterol y la movilidad general (r = -0,382; p < 0,05); sin embargo, se evidenció baja correlación y significancia entre el colesterol y la movilidad progresiva (r = -0,152; p > 0,05) y el colesterol y la vitalidad (r = -0, 251; p > 0,05). Conclusiones: los resultados sugieren una relación interesante entre la calidad seminal y la capacidad de los espermatozoides para liberar colesterol. Sin embargo, es necesario complementar la valoración del colesterol con otras pruebas adicionales con el fin de explorar mejor los altos niveles de calidad seminal en toros Chino Santandereano en semen fresco y descongelado [ABSTRACT FROM AUTHOR]

Se realizó una revisión bibliográfica sobre las estatinas, fármacos análogos del ácido mevalónico que producen una potente inhibición competitiva y reversible de la 3 hidroxi-3-metil-glutaril coenzima A reductasa (HMG-CoA reductasa), principal enzima reguladora de la síntesis endógena de colesterol, y que han denotado una gran relevancia en la actualidad no solo por su acción como hipocolesterolemiante sino también por sus efectos pleiotrópicos. El presente trabajo tuvo como objetivo general describir a las estatinas, para lo cual se utilizaron diversas fuentes de información que sumaron un total de 48 referencias bibliográficas consultadas. Se concluyó que las estatinas, medicamentos orientados inicialmente solo para reducir los niveles del colesterol LDL, se han convertido en uno de los fármacos más esperanzadores del siglo XXI, por su gran potencial antiaterogénico y los resultados satisfactorios alcanzados en su acción contra una amplia gama de enfermedades.

Introdução: Uma das principais causas de morte em homens e mulheres no Brasil são as doenças cardiovasculares, e entre os fatores de risco está a dislipidemia. Objetivo: Avaliar o conhecimento de indivíduos adultos sobre fontes alimentares de colesterol. Materiais e métodos: Foram coletados dados secundários dos prontuários dos usuários de uma Clínica Escola de Nutrição. Os critérios de inclusão foram: usuários adultos atendidos no ano de 2015 com alterações no perfil lipídico. Eles foram convidados via telefone a responder um questionário que envolvia alimentos de origem animal e vegetal onde eles reconheciam ou não o alimento como fonte de colesterol. Resultados: Foram analisados 320 prontuários de pacientes, resultando em 34 pacientes que preenchiam os critérios de inclusão do estudo. Desses, 28 pacientes aceitaram participar, sendo que 78,57% eram do sexo feminino e 57,14% do sexo masculino. Observou-se que todos os participantes reconheciam o ovo como fonte de colesterol, mas alimentos como o peixe e o frango não foram reconhecidos por mais da metade dos indivíduos, e alimentos como a margarina, óleo de soja e abacate foram reconhecidos erroneamente. Observou-se que os participantes com idade de 20 a 39 anos possuíam maior conhecimento dos alimentos fontes de colesterol quando comparados aos da faixa etária de 40 a 59 anos. Conclusão: Mesmo os indivíduos recebendo orientações para redução do consumo de alimentos com elevada fonte de colesterol em uma Clínica Escola de Nutrição, eles não conseguiram reconhecer esses alimentos. Abstract Knowledge about cholesterol food sources between users of a clinical school of nutrition Introduction: One of the main causes of death in men and women in Brazil are cardiovascular disease, and among the risk factors are dyslipidemia. Objective: The aim of the study was to evaluate the knowledge of adults about food sources of cholesterol. Methods: It were collected secondary data from medical records of users of the Clinic School of Nutrition. The inclusion criteria were adult patients seen in 2015 with changes in lipid profile. They were invited by phone to answer a questionnaire involving foods of animal and vegetable origin where they recognized or not the food as a source of cholesterol. Results: It were analyzed 320 patient records, resulting in 34 patients who met the inclusion criteria of the study. Of these, 28 patients agreed to participate, which 78.57% were female and 57.14% male. It was observed that all participants recognized the egg as a source of cholesterol, but foods such as fish and chicken were not recognized for more than half of the individuals, and foods such as margarine, soybean oil and avocado were erroneously recognized. It was observed that participants aged 20 to 39 years had a greater knowledge of food sources of cholesterol when compared to the age group of 40 to 59 years. Conclusion: Even the individuals receiving guidelines for reducing the consumption of high cholesterol foods at a Clinical School of Nutrition, they failed to recognize these foods.

Objetivou-se avaliar a influência da idade e do estresse cíclico por calor durante uma hora por dia, nas concentrações das proteínas, metabólitos e enzimas séricas em frangos de corte de 21 a 42 dias de idade. Foram utilizados 420 pintos de corte machos, da linhagem Cobb Avian48TM, em um delineamento inteiramente casualizado, composto de dois tratamentos e seis repetições. Os tratamentos foram constituídos de dois ambientes térmicos: um para frangos de corte criados em condições naturais de temperatura e umidade do primeiro ao 42° dia de idade (controle); e outro para estressados por calor à 36 °C do 16° ao 42° dia, durante uma hora do dia (12h00m às 13h00m). No 21º, 28º, 35º e 42º dias de idade, foram coletados em duas aves por repetição aproximadamente 5mL de sangue por punção cardíaca. Foram determinadas em cada amostra de soro as concentrações de proteína total, albumina, globulinas, relação A/G, aspartato aminotransferase, alanina aminotransferase, gama glutamiltransferase, ácido úrico, creatinina, colesterol total, triacilgliceróis, lipoproteínas de alta densidade, lipoproteínas de muito baixa densidade, lipoproteínas de baixa densidade e glicose. Para as concentrações de glicose, ácido úrico, alanina aminotransferase, triacilgliceróis e lipoproteínas de muito baixa densidade, não houve diferenças significativas para ambiente e idade. Observou-se interação significativa entre ambiente e idade para os valores de colesterol e lipoproteínas de baixa densidade. Aos 21 dias de idade o colesterol e as LDL-C foram maiores nas aves em estresse comparados àquelas do tratamento controle, o que não ocorreu nas demais idades. A aspartato aminotransferase nos frangos sob estresse cíclico de calor foi maior em comparação ao tratamento controle e apresentou efeito cúbico para ambiente. A idade das aves influenciou os valores de proteínas totais, albumina, globulina, albumina: globulina, creatinina, gama glutamiltransferase e das lipoproteínas de alta densidade. Conclui-se que o estresse cíclico de calor por uma hora, a 36ºC, do 16º ao 42º dia de idade aumenta aspartato aminotransferase, enquanto colesterol e LDL-C são aumentados somente aos 21 dias, indicando que as aves possam ter se adaptado. A idade influencia os valores de AST, GGT, creatinina, proteínas totais, albumina, globulinas, albumina:globulinas, colesterol, HDL-C e LDL-C.

Atualmente a obesidade é uma questão de saúde pública trazendo muitas doenças correlatas como as dislipidemias, doenças cardiovasculares e diabetes. Muitos métodos vêm sendo empregados no tratamento destas consequências como os fitoterápicos, um deles é o extrato de oliveira que possui dentre outras substâncias os compostos fenólicos e antioxidantes. Este estudo teve como objetivo avaliar os efeitos da suplementação do extrato sobre o colesterol e frações (VLDL, HDL, LDL), glicemia de jejum e triglicerídeos. Trata-se de um relato de caso, onde a pessoa estudada foi avaliada previamente por meio de peso (kg), altura (m), bioimpedância (%MM, %MG) e realização de exames bioquímicos de sangue de colesterol e frações (LDL, HDL, VLDL) glicemia de jejum e triglicerídeos. Então passou a ingerir 500 mg de extrato seco de oliveira em cápsulas duas vezes ao dia, uma de manhã e uma a noite, durante 60 dias. Após este período estes exames foram repetidos e obtidos resultados positivos, com redução de glicemia de jejum em 42,18%, Colesterol em 29,91%, LDL em 32,69%, VLDL em 35,31%, triglicerídeos em 35,31% e aumento de HDL em 33,33%. Conclui-se que os resultados foram positivos mostrados a partir dos exames, porém sugere-se que sejam realizados mais estudos, com maior número de pessoas, para confirmar os resultados encontrados. ABSTRACT The effects of olive extract on the reduction of lipid fractions and glycemia: a case study These days obesity is a public health issue bringing many related diseases as dyslipidemia, cardiovascular diseases and diabetes. Many methods have been used in the threatment of these consequences such as phytotherapy, one of them is the olive extract which has among other substances phenolic compounds and antioxidants. The objective of this study was to evaluate the supplementation effects of this extract over cholesterol and fractions (VLDL, HDL, LDL), fasting glycemia and triglycerides. This is a case report where the studied person was previously evaluated by his weight (kg), height (m), bioimpedance (% MM, % BF) and accomplish biochemical cholesterol blood exams and fractions (LDL, HDL, VLDL) fasting glycemia and triglycerides. Then became ingested500 mg of dry olive extract in capsules twice a day, one by morning and one at night for 60 days. After this period the test were repeated and positives results were achieved with the reduction of fasting glycemia by 42.18%, 29.91% in cholesterol, LDL by 32.69%, 35.31% in VLDL, triglycerides in 35.31 %, and HLD was increased by 33.33%. The conclusion, shown in the exams, is that the results were positive, however it is sugested that more studies need to be done with a largest number of people to confirm the results found in this work.

A semente de linhaça (Linun usitatissimum L.) é amplamente utilizada pela população como um alimento funcional, é rica em ácido-linolênico, lignanas e fibras dietéticas, os quais estão relacionados ao controle do colesterol, aumento da saciedade e consequente perda de peso, além de influenciar na redução da incidência de diversas patologias, como as doenças cardiovasculares. O objetivo deste estudo foi avaliar os efeitos da ingestão diária da semente de linhaça dourada triturada sobre o perfil lipídico e antropométrico, bem como a aplicação de questionário para avaliar as implicações desta na saúde dos voluntários. Para tanto, 20 voluntários foram instruídos a ingerir 20 g de semente de linhaça dourada triturada diariamente, durante 60 dias. Os valores de colesterol total, LDL, HDL, triglicerídeos e IMC, foram determinados antes e após a suplementação com linhaça. Para os parâmetros bioquímicos analisados, nenhuma diferença significativa foi observada no período estabelecido. No entanto, uma redução significativa do IMC (10%) dos voluntários foi constatada após tratamento. A suplementação com semente de linhaça teve uma boa aceitação pelos participantes que relataram os benefícios como: regulação intestinal (75%), fonte de energia (25%), emagrecimento (15%) e redução dos sintomas da TPM ou menopausa (54%). Possivelmente, a administração destas sementes por um maior período de tempo, aliado à atividade física e dieta rica em ácidos graxos poli-insaturados podem reduzir os triglicerídios e o colesterol. ABSTRACT The flaxseed role as cholesterol reducing agent and weight loss Flaxseed (Linum usitatissimum L.) is widely used by the population as a functional food, because it is rich in linolenic acid, lignans, and dietary fibers, which are related to cholesterol control, increasing satiety and consequently weight loss, and reducing the incidence of various diseases, including cardiovascular disease. The aim of this study was to evaluate the effects of daily intake of ground golden flaxseed on lipid and anthropometric profile; and to apply a questionnaire to assess the implications of this on the health of volunteers. For this purpose, 20 volunteers were instructed to ingest 20g of ground golden flaxseed, daily, for 60 days. Total cholesterol, LDL, HDL, triglycerides and BMI were determined before and after the flaxseed supplementation. For the biochemical parameters, no significant differences were observed in the established period. Nevertheless, it was found significant BMI reduction in 10% of the volunteers after 60 days of seeds ingestion. Supplementation with flaxseed was well accepted by the participants, who reported the benefits, such as intestinal regulation (75%), energy source (25%), weight loss (15%) and reduction of PMS or menopause symptoms (54%). Possibly the flaxseeds administration for a longer time, combined with physical activity and a diet rich in polyunsaturated fatty acids might reduce triglycerides and cholesterol.

A obesidade é uma doença nutricional muito frequente em cães de meia idade a velhos, sendo considerada uma condição patológica que leva ao acúmulo de gordura corporal. O objetivo deste estudo foi avaliar a condição corporal de cães e identificar o perfil de lipídios séricos e glicose, e analisar essa correspondência com faixa etária, sexo e castração. Foram selecionados 30 cães de ambos os sexos que faziam parte da rotina da Clínica Veterinária Uningá, com anuência dos proprietários. Os cães apresentavam bom estado de saúde e, dentre estes, foram escolhidos 10 cães para o controle, machos (n=5) e fêmeas (n=5), todos inteiros, com ECC ideal (ECC=5), e para o teste, animais machos (n=10) e fêmeas (n=10) castrados com ECC=9, sendo estes considerados obesos. No grupo faixa etária (n=11) com idade de 2 a 7 anos, e maior de 7 anos (n=9). No laboratório de Patologia Clínica da Uningá foram realizados os exames bioquímicos de colesterol, triglicerídeos e glicose. Após jejum alimentar superior a 12 horas, foi feita a coleta de sangue por meio de punção da veia jugular. Para essas análises, foram utilizados kits comerciais (ANALISA). Os dados obtidos foram analisados pelo programa estatístico SAEG (2007) mediante aplicação do teste de Tukey p(

Abstract Background: The use of autonomic modulation as a predictor of cardiovascular risk in women with breast cancer is important. Objective: To evaluate the cardiac autonomic modulation of postmenopausal women using aromatase inhibitors for breast cancer treatment, as well as its relation with the following biochemical variables. Methods: Postmenopausal women who did not have breast cancer (n = 33) and postmenopausal women with breast cancer (n = 15). For evaluation of the autonomic modulation the heart rate was recorded beat-to-beat for 30 minutes and the series of RR intervals obtained were used to calculate the following heart rate variability indices: Mean RR ms, SDNN (standard deviation of all normal RR intervals, expressed in milliseconds) ms, Mean HR, RMSSD (square root of the mean of the squared differences between adjacent normal RR interval) ms, NN50 (number of pairs of successive NNs that differ by more than 50 ms) count, pNN50% (proportion of NN50 divided by total number of NNs), RRtri (RR triangular), TINN (triangular interpolation of NN interval) ms, SD1 ms, SD2 ms, LF ms2, HF ms2, LH/HF ms2. The values of biochemical variables (fasting glycemia, triglycerides, HDL-cholesterol, and C-reactive protein) were analyzed by blood sample. Results: Lower values of heart rate variability indices were observed in postmenopausal women with breast cancer in relation to postmenopausal women who did not have breast cancer: Mean RR (p = 0.03); SDNN (p = 0.03); RMSSD (p = 0.03); NN50 count (p = 0.03); pNN50 % (p = 0.03); RRtri (p = 0.02); SD1 (p = 0.01); SD2 (p = 0.02); LF ms2 (p = 0.01); HF ms2 (p = 0.03).There was an inversely proportional correlation between the indices SDNN, SD2, and HFms2 with triglycerides (SDNN p = 0.04; SD2 p = 0.04; HF ms2 p = 0.04). No statistically significant correlations were found between heart rate variability indices and others variables. Statistical significance was set at 5% for all analyses. Conclusion: Women with breast cancer present reduced autonomic modulation and in these women of heart rate variability indices are inversely correlated with triglyceride values.

Introduction: Introduction: yerba mate is a traditional drink consumed in South America, produced from toasted leaves of Ilex paraguariensis. Several studies have demonstrated its lipid-lowering properties due to the presence of polyphenols and saponins. Objective: to analyze the effect of daily yerba mate consumption on the values of serum lipids and body composition in overweight women. Methods: 119 overweight women between 25 and 50 years were divided into three groups: Mate and Diet (MD), Mate without Diet (M), and Water and Diet (AD). For 12 weeks the M and MD groups were supplemented with mate, while the AD and MD groups maintained a hypocaloric food plan. Anthropometric measurements and blood tests (total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides) were taken at the beginning and at the end of the study. The statistical analysis was performed using Student's t-test or Wilcoxon's test for paired samples and ANOVA (p < 0.05 was considered significant in all cases). Results: total cholesterol decreased in all groups (10.21 mg/dL in MD, 18.29 mg/dL in M, and 17.63 mg/dL in AD, without differences between groups). LDL-cholesterol decreased in both groups with mate (8.07 mg/dL in MD, 16.04 mg/dL in M, without differences between groups) while HDL-cholesterol decreased in M (2.09 mg/dL). On the other hand, triglycerides fell 10.74 mg/dL in the MD group. Conclusions: a daily intake of mate helps reduce total cholesterol and LDL-cholesterol, and provides a reduction of triglycerides along with a low-calorie diet. [ABSTRACT FROM AUTHOR]

Background: For several years, many attempts have been made for the improvement of liposomal stability. In 1986, Payne et al, introduced the concept of Pro-liposome for liposome preparation in order to avoid physicochemical instability encountered in some liposome suspensions such as aggregation, fusion, hydrolysis, and/or oxidation. Objective: The objective of this review is to focus on different aspects related to Proliposomes, their method of preparation, characterization techniques and pointing out its scope in drug delivery systems. Methods: Proliposomes are a new form of drug delivery systems. They are dry, free-flowing granular products composed of drug and phospholipid which, upon addition of water, disperse to form a multi- lamellar liposomal suspension. Results and Discussion: These Proliposomes are nearly as good as or perhaps better than conventional liposomes. In the present review attempt has been made to briefly explain the concept of Proliposomes with a focus on its components, preparation, characterizations and their field of application. Conclusion: Extensive survey of literatures and collected data suggests that Pro-liposomes are promising drug carriers for the future. [ABSTRACT FROM AUTHOR]

Astmul este o afecţiune heterogenă caracterizată prin inflamaţia cronică a căilor aeriene. Colesterolul este un factor proinflamator corelat, în unele studii cu inflamaţia din astm. În Spitalul Clinic de Copii „Dr. Victor Gomoiu”, în perioada ianuarie 2016-septembrie 2018, a fost initiat un studiu prospectiv care a inclus 100 de copii în vârstă de 5-18 ani, diagnosticaţi cu astm alergic şi sensibilizare aeroalergenică. Toţi pacienţii înrolaţi au fost monitorizaţi privind nivelul colesterolului, treapta terapeutică primită şi gradul de control al astmului. Obiectivul studiului a fost să se evalueze dacă există o asociere între valorile colesterolului seric şi controlul astmului şi între colesterolul seric şi treapta de tratament de control (ca indicator al severităţii astmului). Concluzii. În lotul studiat, pacienţii încadraţi în categoriile de astm parţial controlat şi necontrolat au fost în procent mai mare cu valori crescute ale colesterolului seric comparativ cu cei cu astm controlat; copiii înregistraţi în categoriile de astm moderat şi sever au fost în procent mai mare cu colesterol seric total crescut faţă de cei cu astm uşor. [ABSTRACT FROM AUTHOR]

Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archivos Latinoamericanos de Nutrición is the property of Sociedad Latinoamericana de Nutricion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Actualizaciones en Osteología is the property of Asociacion Argentina de Osteologia y Metabolismo Mineral and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)