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102. Influence of hospital volume on outcomes of percutaneous atrial septal defect and patent foramen ovale closure: A 10-years us perspective

Author

Singh, Vikas, Badheka, Apurva O., Patel, Nileshkumar J., Chothani, Ankit, Mehta, Kathan, Arora, Shilpkumar, Patel, Nilay, Deshmukh, Abhishek, Shah, Neeraj, Savani, Ghanshyambhai T., Rathod, Ankit, Manvar, Sohilkumar, Thakkar, Badal, Panchal, Vinaykumar, Patel, Jay, Palacios, Igor F., Rihal, Charanjit S., Cohen, Mauricio G., OʼNeill, William, and De Marchena, Eduardo

Published
2015
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105. The paradoxical use of cardiac catheterization in patients with non–ST-elevation acute coronary syndromes: Lessons from the Can Rapid Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the ACC /AHA Guidelines (CRUSADE) Quality Improvement Initiative

Author

Cohen, Mauricio G., Filby, Steven J., Roe, Matthew T., Chen, Anita Y., Menon, Venu, Stouffer, George A., Gibler, W. Brian, Smith, Sidney C., Jr, Pollack, Charles V., Jr, Peterson, Eric D., and Ohman, E. Magnus

Published
2009
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106. Health-related quality of life 1-3 years post-myocardial infarction: its impact on prognosis

Author

Pocock, Stuart, Brieger, David B, Owen, Ruth, Chen, Jiyan, Cohen, Mauricio G, Goodman, Shaun, Granger, Christopher B, Nicolau, José C, Simon, Tabassome, Westermann, Dirk, Yasuda, Satoshi, Hedman, Katarina, Mellström, Carl, Andersson Sundell, Karolina, and Grieve, Richard

Abstract

OBJECTIVE: To assess associations of health-related quality of life (HRQoL) with patient profile, resource use, cardiovascular (CV) events and mortality in stable patients post-myocardial infarction (MI). METHODS: The global, prospective, observational TIGRIS Study enrolled 9126 patients 1-3 years post-MI. HRQoL was assessed at enrolment and 6-month intervals using the patient-reported EuroQol-5 dimension (EQ-5D) questionnaire, with scores anchored at 0 (worst possible) and 1 (perfect health). Resource use, CV events and mortality were recorded during 2-years' follow-up. Regression models estimated the associations of index score at enrolment with patient characteristics, resource use, CV events and mortality over 2-years' follow-up. RESULTS: Among 8978 patients who completed the EQ-5D questionnaire, 52% reported 'some' or 'severe' problems on one or more health dimensions. Factors associated with a lower index score were: female sex, older age, obesity, smoking, higher heart rate, less formal education, presence of comorbidity (eg, angina, stroke), emergency room visit in the previous 6 months and non-ST-elevation MI as the index event. Compared with an index score of 1 at enrolment, a lower index score was associated with higher risk of all-cause death, with an adjusted rate ratio of 3.09 (95% CI 2.20 to 4.31), and of a CV event, with a rate ratio of 2.31 (95% CI 1.76 to 3.03). Patients with lower index score at enrolment had almost two times as many hospitalisations over 2-years' follow-up. CONCLUSIONS: Clinicians managing patients post-acute coronary syndrome should recognise that a poorer HRQoL is clearly linked to risk of hospitalisations, major CV events and death. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov Registry (NCT01866904) (https://clinicaltrials.gov).

Published
2021

108. Transradial Access for High-Risk Percutaneous Coronary Intervention: Implications of the Risk-Treatment Paradox

Author

Amin, Amit P., primary, Rao, Sunil V., additional, Seto, Arnold H., additional, Thangam, Manoj, additional, Bach, Richard G., additional, Pancholy, Samir, additional, Gilchrist, Ian C., additional, Kaul, Prashant, additional, Shah, Binita, additional, Cohen, Mauricio G., additional, Gluckman, Ty J., additional, Bortnick, Anna, additional, DeVries, James T., additional, Kulkarni, Hemant, additional, and Masoudi, Frederick A., additional

Published
2021
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110. Diabetes association with self-reported health, resource utilization, and prognosis post-myocardial infarction

Author

Nicolau, José C, Brieger, David, Owen, Ruth, Furtado, Remo HM, Goodman, Shaun G, Cohen, Mauricio G, Simon, Tabassome, Westermann, Dirk, Granger, Christopher B, Grieve, Richard, Yasuda, Satoshi, Chen, Jiyan, Hedman, Katarina, Mellström, Carl, Brandrup-Wognsen, Gunnar, and Pocock, Stuart J

Abstract

BACKGROUND: Diabetes mellitus (DM) is associated with increased cardiovascular (CV) risk. We compared health-related quality of life (HRQoL), healthcare resource utilization (HRU), and clinical outcomes of stable post-myocardial infarction (MI) patients with and without DM. HYPOTHESIS: In post-MI patients, DM is associated with worse HRQoL, increased HRU, and worse clinical outcomes. METHODS: The prospective, observational long-term risk, clinical management, and healthcare Resource utilization of stable coronary artery disease study obtained data from 8968 patients aged ≥50 years 1 to 3 years post-MI (369 centers; 25 countries). Patients with ≥1 of the following risk factors were included: age ≥65 years, history of a second MI >1 year before enrollment, multivessel coronary artery disease, creatinine clearance ≥15 and

Published
2020

118. The Use of Vascular Closure Devices and Impact on Major Bleeding and Net Adverse Clinical Events (NACEs) in Balloon Aortic Valvuloplasty: A Sub-Analysis of the BRAVO Study

Author

OʼNeill, Brian, Singh, Vikas, Kini, Annapoorna, Mehran, Roxana, Jacobs, Evan, Knopf, David, Alfonso, Carlos E., Martinez, Claudia A., Martinezclark, Pedro, OʼNeill, William, Heldman, Alan W., Yu, Jennifer, Baber, Usman, Kovacic, Jason C., Dangas, George, Sharma, Samin, Sartori, Samantha, and Cohen, Mauricio G.

Published
2014
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119. Fourth universal definition of myocardial infarction (2018)

Author

Thygesen, Kristian, Alpert, Joseph S., Jaffe, Allan S., Chaitman, Bernard R., Bax, Jeroen J., Morrow, David A., White, Harvey D., Mickley, Hans, Crea, Filippo, Van De Werf, Frans, Bucciarelli-Ducci, Chiara, Katus, Hugo A., Pinto, Fausto J., Antman, Elliott M., Hamm, Christian W., De Caterina, Raffaele, Januzzi, James L., Apple, Fred S., Garcia, Maria Angeles Alonso, Underwood, S. Richard, Canty, John M., Lyon, Alexander R., Devereaux, P. J., Zamorano, Jose Luis, Lindahl, Bertil, Weintraub, William S., Newby, L. Kristin, Virmani, Renu, Vranckx, Pascal, Cutlip, Don, Gibbons, Raymond J., Smith, Sidney C., Atar, Dan, Luepker, Russell V., Robertson, Rose Marie, Bonow, Robert O., Steg, P. Gabriel, O’Gara, Patrick T., Fox, Keith A. A., Hasdai, David, Aboyans, Victor, Achenbach, Stephan, Agewall, Stefan, Alexander, Thomas, Avezum, Alvaro, Barbato, Emanuele, Bassand, Jean-Pierre, Bates, Eric, Bittl, John A., Breithardt, Güenter, Bueno, Héctor, Bugiardini, Raffaele, Cohen, Mauricio G., Dangas, George, De Lemos, James A., Delgado, Victoria, Filippatos, Gerasimos, Fry, Edward, Granger, Christopher B., Halvorsen, Sigrun, Hlatky, Mark A., Ibanez, Borja, James, Stefan, Kastrati, Adnan, Leclercq, Christophe, Mahaffey, Kenneth W., Mehta, Laxmi, Müller, Christian, Patrono, Carlo, Piepoli, Massimo Francesco, Piñeiro, Daniel, Roffi, Marco, Rubboli, Andrea, Sharma, Samin, Simpson, Iain A., Tendera, Michael, Valgimigli, Marco, Van Der Wal, Allard C., Windecker, Stephan, Thygesen, Kristian, Alpert, Joseph S., Jaffe, Allan S., Chaitman, Bernard R., Bax, Jeroen J., Morrow, David A., White, Harvey D., Mickley, Han, Crea, Filippo, Van De Werf, Fran, Bucciarelli-Ducci, Chiara, Katus, Hugo A., Pinto, Fausto J., Antman, Elliott M., Hamm, Christian W., De Caterina, Raffaele, Januzzi, James L., Apple, Fred S., Garcia, Maria Angeles Alonso, Underwood, S. Richard, Canty, John M., Lyon, Alexander R., Devereaux, P.J., Zamorano, Jose Lui, Lindahl, Bertil, Weintraub, William S., Newby, L. Kristin, Virmani, Renu, Vranckx, Pascal, Cutlip, Don, Gibbons, Raymond J., Smith, Sidney C., Atar, Dan, Luepker, Russell V., Robertson, Rose Marie, Bonow, Robert O., Steg, P. Gabriel, O’Gara, Patrick T., Fox, Keith A. A., Hasdai, David, Aboyans, Victor, Achenbach, Stephan, Agewall, Stefan, Alexander, Thoma, Avezum, Alvaro, Barbato, Emanuele, Bassand, Jean-Pierre, Bates, Eric, Bittl, John A., Breithardt, Güenter, Bueno, Héctor, Bugiardini, Raffaele, Cohen, Mauricio G., Dangas, George, De Lemos, James A., Delgado, Victoria, Filippatos, Gerasimo, Fry, Edward, Granger, Christopher B., Halvorsen, Sigrun, Hlatky, Mark A., Ibanez, Borja, James, Stefan, Kastrati, Adnan, Leclercq, Christophe, Mahaffey, Kenneth W., Mehta, Laxmi, Müller, Christian, Patrono, Carlo, Piepoli, Massimo Francesco, Piñeiro, Daniel, Roffi, Marco, Rubboli, Andrea, Sharma, Samin, Simpson, Iain A., Tendera, Michael, Valgimigli, Marco, Van Der Wal, Allard C., Windecker, Stephan, and Cardiology

Subjects
CHRONIC KIDNEY-DISEASE, Type 5 MI, Cardiac & Cardiovascular Systems, END-POINT DEFINITIONS, Epidemiology, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Infarction, 030204 cardiovascular system & hematology, Type 1 MI, ACUTE CORONARY SYNDROME, Severity of Illness Index, Electrocardiography, High sensitivity cardiac troponin, 0302 clinical medicine, Silent Myocardial Infarction, Medicine, 030212 general & internal medicine, Myocardial infarction, Coronary Artery Bypass, Re-infarction, Type 4c MI, 1102 Cardiorespiratory Medicine and Haematology, Type 2 MI, Troponin, RULE-OUT STRATEGIES, ST-SEGMENT-ELEVATION, Silent myocardial infarction, Myocardial infarction with non-obstructive coronary arteries (MINOCA), Recurrent myocardial infarction, CARDIOVASCULAR MAGNETIC-RESONANCE, Myocardial injury, Practice Guidelines as Topic, Cardiology, Cardiac troponin, Kidney Diseases, Type 4b MI, Takotsubo syndrome, Cardiology and Cardiovascular Medicine, Life Sciences & Biomedicine, BUNDLE-BRANCH BLOCK, Diagnostic Imaging, Acute coronary syndrome, medicine.medical_specialty, Consensus, Type 3 MI, JOINT EUROPEAN-SOCIETY, Coronary Restenosis, Cardiac procedural myocardial injury, Expert Consensus Document, Prior myocardial infarction, Type 4a MI, 03 medical and health sciences, Percutaneous Coronary Intervention, Takotsubo Cardiomyopathy, Terminology as Topic, Physiology (medical), Internal medicine, Humans, Heart Failure, Community and Home Care, Science & Technology, Bundle branch block, business.industry, LONG-TERM MORTALITY, Congresses as Topic, medicine.disease, Cardiovascular System & Hematology, ESC Scientific Document Group, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, SENSITIVITY CARDIAC TROPONIN, Cardiovascular System & Cardiology, Long term mortality, business, Biomarkers
Abstract

Kristian Thygesen∗ (Denmark) Joseph S. Alpert∗ (USA) Allan S. Jaffe (USA) Bernard R. Chaitman (USA) Jeroen J. Bax (The Netherlands) David A. Morrow (USA) Harvey D. White∗ (New Zealand) Hans Mickley (Denmark) Filippo Crea (Italy) Frans Van de Werf (Belgium) Chiara Bucciarelli-Ducci (

Published
2019

120. Health-related quality of life 1–3 years post-myocardial infarction: its impact on prognosis

Author

Pocock, Stuart, primary, Brieger, David B, additional, Owen, Ruth, additional, Chen, Jiyan, additional, Cohen, Mauricio G, additional, Goodman, Shaun, additional, Granger, Christopher B, additional, Nicolau, José C, additional, Simon, Tabassome, additional, Westermann, Dirk, additional, Yasuda, Satoshi, additional, Hedman, Katarina, additional, Mellström, Carl, additional, Andersson Sundell, Karolina, additional, and Grieve, Richard, additional

Published
2021
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122. Considerations for cardiac catheterization laboratory procedures during the COVID-19 pandemic perspectives from the Society for Cardiovascular Angiography and Interventions Emerging Leader Mentorship (SCAI ELM) Members and Graduates

Author

Szerlip, Molly, Anwaruddin, Saif, Aronow, Herbert D., Cohen, Mauricio G., Daniels, Matthew J., Dehghani, Payam, Drachman, Douglas E., Elmariah, Sammy, Feldman, Dmitriy N., Garcia, Santiago, Giri, Jay, Kaul, Prashant, Kapur, Navin K., Kumbhani, Dharam J., Meraj, Perwaiz M., Morray, Brian, Nayak, Keshav R., Parikh, Sahil A., Sakhuja, Rahul, Schussler, Jeffrey M., Seto, Arnold, Shah, Binita, Swaminathan, Rajesh V., Zidar, David A., and Naidu, Srihari S.

Subjects
Male, Cardiac Catheterization, Cross Infection/prevention & control, Pneumonia, Viral, Cardiology, Cardiac Catheterization/standards, Coronary Angiography, Humans, Hospital Mortality, Pandemics/prevention & control, Pandemics, Personal Protective Equipment, Pneumonia, Viral/epidemiology, Societies, Medical, Coronary Angiography/methods, Cross Infection, Mentors, COVID-19, General Medicine, Laboratories, Hospital, Survival Analysis, United States, Leadership, Personal Protective Equipment/statistics & numerical data, Radiology Nuclear Medicine and imaging, Practice Guidelines as Topic, Coronavirus Infections/epidemiology, Female, Practice Guidelines as Topic/standards, Cardiology and Cardiovascular Medicine, Coronavirus Infections
Abstract

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is highly infectious, carries significant morbidity and mortality, and has rapidly resulted in strained health care system and hospital resources. In addition to patient-related care concerns in infected individuals, focus must also relate to diminishing community spread, protection of staff, case selection, and concentration of resources. The current document based on available data and consensus opinion addresses appropriate catheterization laboratory preparedness for treating these patients, including procedure-room readiness to minimize external contamination, safe donning and doffing of personal protective equipment (PPE) to eliminate risk to staff, and staffing algorithms to minimize exposure and maximize team availability. Case selection and management of both emergent and urgent procedures are discussed in detail, including procedures that may be safely deferred or performed bedside.

Published
2020

123. TAVR in Low-Population Density Areas: Assessing Healthcare Access for Older Adults with Severe Aortic Stenosis

Author

Damluji, Abdulla A, Fabbro, Michael, Epstein, Richard H, Rayer, Stefan, Wang, Ying, Moscucci, Mauro, Cohen, Mauricio G, Carroll, John D, Messenger, John C, Resar, Jon R, Cohen, David J, Sherwood, Matthew W, O’Connor, Christopher M, and Batchelor, Wayne

Subjects
Aged, 80 and over, Male, Population Density, Travel, Time Factors, Databases, Factual, Age Factors, Aortic Valve Stenosis, Severity of Illness Index, Article, Health Services Accessibility, Transcatheter Aortic Valve Replacement, Treatment Outcome, Catchment Area, Health, Residence Characteristics, Florida, Humans, Female, Hospital Mortality, Rural Health Services, Healthcare Disparities, Aged, Retrospective Studies
Abstract

BACKGROUND: Restricting TAVR to centers based on volume thresholds alone can potentially create unintended disparities in healthcare access. We aimed to compare the influence of population density in state of Florida in regard to access to TAVR, TAVR-utilization rates, and in-hospital mortality. METHODS AND RESULTS: From 2011–2016, we used data from the AHCA to calculate travel time and distance for each TAVR-patient by comparing their home address to their TAVR-facility ZIP-code. Travel time and distance, TAVR rates, and mortality were compared across categories of low to high population density (population per sq. mi of land). Of the 6,531 patients included, the mean (SD) age was 82 (9) years, 43% were female and 91% were Caucasian. Patients residing in the lowest category (

Published
2020

124. Predicting risk of cardiovascular events 1 to 3 years post-myocardial infarction using a global registry

Author

Pocock, Stuart J, Brieger, David, Gregson, John, Chen, Ji Y, Cohen, Mauricio G, Goodman, Shaun G, Granger, Christopher B, Grieve, Richard, Nicolau, Jose C, Simon, Tabassome, Westermann, Dirk, Yasuda, Satoshi, Hedman, Katarina, Rennie, Kirsten L, Sundell, Karolina Andersson, and TIGRIS Study Investigators

Subjects
Aged, 80 and over, Male, Models, Cardiovascular, Myocardial Infarction, Middle Aged, Prognosis, Risk Assessment, cardiac risk factors and prevention, Cardiovascular Diseases, Risk Factors, Humans, Female, Prospective Studies, Registries, coronary artery disease, Aged
Abstract

BACKGROUND: Risk prediction tools are lacking for patients with stable disease some years after myocardial infarction (MI). HYPOTHESIS: A practical long-term cardiovascular risk index can be developed. METHODS: The long-Term rIsk, Clinical manaGement and healthcare Resource utilization of stable coronary artery dISease in post-myocardial infarction patients prospective global registry enrolled patients 1 to 3 years post-MI (369 centers; 25 countries), all with ≥1 risk factor (age ≥65 years, diabetes mellitus requiring medication, second prior MI, multivessel coronary artery disease, or chronic non-end-stage kidney disease [CKD]). Self-reported health was assessed with EuroQoL-5 dimensions. Multivariable Poisson regression models were used to determine key predictors of the primary composite outcome (MI, unstable angina with urgent revascularization [UA], stroke, or all-cause death) over 2 years. RESULTS: The primary outcome occurred in 621 (6.9%) of 9027 eligible patients: death 295 (3.3%), MI 195 (2.2%), UA 103 (1.1%), and stroke 58 (0.6%). All events accrued linearly. In a multivariable model, 11 significant predictors of primary outcome (age ≥65 years, diabetes, second prior MI, CKD, history of major bleed, peripheral arterial disease, heart failure, cardiovascular hospitalization (prior 6 months), medical management (index MI), on diuretic, and poor self-reported health) were identified and combined into a user-friendly risk index. Compared with lowest-risk patients, those in the top 16% had a rate ratio of 6.9 for the primary composite, and 18.7 for all-cause death (overall c-statistic; 0.686, and 0.768, respectively). External validation was performed using the Australian Cooperative National Registry of Acute Coronary Care, Guideline Adherence and Clinical Events registry (c-statistic; 0.748, and 0.849, respectively). CONCLUSIONS: In patients >1-year post-MI, recurrent cardiovascular events and deaths accrue linearly. A simple risk index can stratify patients, potentially helping to guide management.

Published
2020
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127. Clinical characteristics, process of care, and outcomes of Hispanic patients presenting with nonuST-segment elevation acute coronary syndromes: results from Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines (CRUSADE)

Author

Cohen, Mauricio G., Roe, Matthew T., Mulgund, Jyotsna, Peterson, Eric D., Sonel, Ali F., Menon, Venu, Smith, Sidney C., Saucedo, Jorge F., Lytle, Barbara L., Pollack, Charles V., Jr., Garza, Luis, Gibler, W. Brian, and Ohman, E. Magnus

Subjects
Hispanic Americans -- Health aspects, Hispanic Americans -- Research, Hispanic Americans -- Care and treatment, Cardiac patients -- Health aspects, Cardiac patients -- Care and treatment, Cardiovascular diseases -- Care and treatment, Cardiovascular diseases -- Patient outcomes, Health
Published
2006

129. A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization

Author

Cohen, Mauricio G., Pascua, J. Andres, Garcia-Ben, Marta, Rojas-Matas, Carlos A., Gabay, Jose M., Berrocal, Daniel H., Tan, Walter A., Stouffer, George A., Montoya, Mario, Fernandez, Alejandro D., Halac, Marcelo E., and Grinfeld, Liliana R.

Subjects
Renal artery obstruction -- Research, Hypertension -- Causes of, Cardiac catheterization -- Patient outcomes, Health
Published
2005

131. Balloon Mitral Valvuloplasty in the United States: A 13-Year Perspective

Author

Badheka, Apurva O., Shah, Neeraj, Ghatak, Abhijit, Patel, Nileshkumar J., Chothani, Ankit, Mehta, Kathan, Singh, Vikas, Patel, Nilay, Grover, Peeyush, Deshmukh, Abhishek, Panaich, Sidakpal S., Savani, Ghanshyambhai T., Bhalara, Vipulkumar, Arora, Shilpkumar, Rathod, Ankit, Desai, Harit, Kar, Saibal, Alfonso, Carlos, Palacios, Igor F., Grines, Cindy, Schreiber, Theodore, Rihal, Charanjit S., Makkar, Raj, Cohen, Mauricio G., O'Neill, William, and de Marchena, Eduardo

Published
2014
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133. A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial

Author

Povsic, Thomas J., Vavalle, John P., Aberle, Laura H., Kasprzak, Jaroslaw D., Cohen, Mauricio G., Mehran, Roxana, Bode, Christoph, Buller, Christopher E., Montalescot, Gilles, Cornel, Jan H., Rynkiewicz, Andrzej, Ring, Michael E., Zeymer, Uwe, Natarajan, Madhu, Delarche, Nicolas, Zelenkofske, Steven L., Becker, Richard C., and Alexander, John H.

Published
2013
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142. Clinical characteristics, process of care, and outcomes of Hispanic patients presenting with non–ST-segment elevation acute coronary syndromes: Results from Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines (CRUSADE)

Author

Cohen, Mauricio G., Roe, Matthew T., Mulgund, Jyotsna, Peterson, Eric D., Sonel, Ali F., Menon, Venu, Smith, Sidney C., Jr, Saucedo, Jorge F., Lytle, Barbara L., Pollack, Charles V., Jr, Garza, Luis, Gibler, W. Brian, and Ohman, E. Magnus

Published
2006
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145. Variation in patient management and outcomes for acute coronary syndromes in Latin America and North America: results from the Platelet IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) trial

Author

Cohen, Mauricio G., Pacchiana, Cynthia M., Corbalan, Ramon, Perez, Jesus E. Isea, Ponte, Carlos I., Oropeza, Elsa Silva, Diaz, Rafael, Paolasso, Ernesto, Izasa, Daniel, Rodas, Marco A., Urrutia, Carlos E., Harrington, Robert A., Topol, Eric J., and Califf, Robert M.

Subjects
Heart attack -- Care and treatment, Discrimination in medical care -- Latin America, Health
Published
2001

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