210 results on '"Cipriani, E"'
Search Results
102. SMART Project: Field test results of different traffic monitoring technologies
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Bellucci, P., Cipriani, E., Gori, Stefano, GAETANO FUSCO, Bellucci, Patrizia, Cipriani, Ernesto, Fusco, Gaetano, and Petrelli, Marco
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experiment ,test ,sensor devices ,Traffic monitoring
103. Optimal location of traffic count sections
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Cipriani, E., GAETANO FUSCO, Gori, S., Mao B, Tian Z, Sun Q, Cipriani, Ernesto, Fusco, G, Gori, S., and Gori, Stefano
- Abstract
In this paper, authors deal with the problem of optimal location of traffic count sections and propose two new rules that aim at enhancing the reliability of the estimated O/D matrices in case of limited availability of sections to be located. These rules are tested on a real size extra-urban road network and are compared to a state-of-the art rule that is widely used in practical applications.
104. Investigating the Efficiency of a Gradient Approximation Approach for the Solution of Dynamic Demand Estimation Problems
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Cipriani, E., Florian, M., Mahut, M., and Marialisa NIGRO
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Economics and Finance, Environment, Urban and Regional Studies - Abstract
Traffic assignment is a set of criteria through which the demand for mobility is distributed over the links of a transport network. Over the last 30 years, Dynamic Traffic Assignment (DTA) models have been developed to support time-dependent analyses in nascent fields that need to take into account the temporal distribution of demand and supply. In this book, leading international experts in the field provide a state-of-the-art overview of fundamental DTA research and practice, identifying weaknesses and major challenges for future research.
105. Theoretical and experimental comparison of class F vs.Class F-1 PAs
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Cipriani, E., Paolo Colantonio, Giannini, F., and Giofrè, R.
106. A second harmonic tuned power amplifier in LDMOS technology
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Cipriani, E., Colantonio, P., Giannini, F., and Rocco Giofrè
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Radar ,Power amplifiers ,Measurement results ,Second harmonics ,MOS devices ,Radio waves ,Drain efficiencies ,Output powers ,Microwaves ,Settore ING-INF/01 - Elettronica
107. The effect of 2nd harmonic control on power amplifiers performances
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Cipriani, E., Colantonio, P., and FRANCO GIANNINI
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III-V semiconductors ,wide band gap semiconductors ,gallium compounds ,harmonic distortion ,microwave power amplifiers ,GaN ,frequency 3 GHz ,hybrid power amplifiers ,microwave power amplifier ,power amplifier design ,second harmonic control ,second harmonic tuned power amplifier ,Bandwidth ,Harmonic analysis ,Microwave circuits ,Microwave communication ,Power generation ,Power system harmonics ,Settore ING-INF/01 - Elettronica
108. Effects of gate bias voltage and compression level on a X-band MMIC class F -1 PA
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Cipriani, E., Colantonio, P., Giannini, F., and Rocco Giofrè
109. GaN power amplifiers: Results and prospective
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Giofrè, R., Piazzon, L., Colantonio, P., Cipriani, E., and FRANCO GIANNINI
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Settore ING-INF/01 - Elettronica
110. Nanofibrous Scaffolds For Tissue Engineering
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Tonda Turo, C., Chiono, V., Audisio, C., Cipriani, E., Francesca Boccafoschi, Geuna, S., Zanetti, M., Perroteau, I., and Ciardelli, G.
111. The SMART project - speed measurement validation in real traffic condition
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Bellucci, P., primary, Cipriani, E., additional, Gagliarducci, M., additional, and Riccucci, C., additional
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- View/download PDF
112. Bluetooth Traffic Data for Urban Travel Time Forecast
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Ernesto Cipriani, Andrea Gemma, Stefano Carrese, Livia Mannini, Umberto Crisalli, Carrese, S., Cipriani, E., Crisalli, U., Gemma, A., Mannini, L., Carrese, S., Cipriani, E., Crisalli, U., Gemma, A., and Mannini, L.
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path travel time ,050210 logistics & transportation ,Sensors ,Computer science ,Bluetooth ,05 social sciences ,Real-time computing ,0211 other engineering and technologies ,Statistical model ,02 engineering and technology ,Data-driven ,law.invention ,Travel time ,law ,021105 building & construction ,0502 economics and business ,Path (graph theory) ,Traffic conditions ,Network performance ,Settore ICAR/05 ,Autoregressive integrated moving average ,online forecast ,traffic data ,Sensor - Abstract
This paper investigates the problem of the network performance forecast by using traffic data acquired via Bluetooth devices in order to provide advanced models and tools for the prediction of congestion effects in urban areas. A data driven approach is adopted where different statistical models are tested within a methodology framework in which the above data are filtered, cleaned and fused for a better prediction of path travel times. The proposed approach has been applied to the city of Rome: performances that better fit observed traffic conditions have been obtained by adopting an ARIMA based model whose promising results of online forecast are presented and discussed.
- Published
- 2021
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113. A Gaussian mixture model and data fusion approach for urban travel time forecast
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Ernesto Cipriani, Umberto Crisalli, Andrea Gemma, Stefano Carrese, Livia Mannini, Gemma, A., Mannini, L., Carrese, S., Cipriani, E., Crisalli, U., Gemma, A., Mannini, L., Carrese, S., Cipriani, E., and Crisalli, U.
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Computer science ,business.industry ,Travel time forecast ,Real-time computing ,Floating car data ,Data fusion ,Sensor fusion ,Mixture model ,computer.software_genre ,Moving-average model ,Data modeling ,Network management ,Gaussian mixture model ,Network performance ,business ,computer ,Data integration - Abstract
Travel time information is gaining increasing importance as traffic performance measure from the perspective of both drivers to understand traffic conditions and network management to properly monitor and control the evolution of traffic conditions. Aiming at forecasting path travel times in congested urban areas, this paper proposes a data- driven approach in which traffic data are collected via Bluetooth and mobile Floating Car Data devices. Such data are used to improve the accuracy of the detected information by means of a Gaussian Mixture Model (GMM) and a Bayesian data fusion approach. The GMM is applied to estimate the travel time and not only its distribution and it is calibrated for each time interval and updated with every available data on real time. An Auto- Regressive Integrated Moving Average model is used for the travel time forecast. An application to a real-life test case in the city of Rome shows the goodness of the proposed approach for better online network performance forecast.
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- 2021
114. Covid-19 Transport Analytics. Analysis of Rome Mobility During Coronavirus Pandemic Era
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Brinchi, Stefano, Carrese, Stefano, Cipriani, Ernesto, Colombaroni, Chiara, Crisalli, Umberto, Fusco, Gaetano, Gemma, Andrea, Isaenko, Natalia, Mannini, Livia, Petrelli, Marco, Brinchi, S., Carrese, S., Cipriani, E., Colombaroni, C., Crisalli, U., Fusco, G., Gemma, A., Isaenko, N., Mannini, L., Petrelli, M., Brinchi, S., Carrese, S., Cipriani, E., Colombaroni, C., Crisalli, U., Fusco, G., Gemma, A., Isaenko, N., Mannini, L., and Petrelli, M.
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Coping (psychology) ,Coronavirus disease 2019 (COVID-19) ,business.industry ,transport modelling ,Big data ,Data science ,Transport analytic ,Transport modelling ,Sustainable transport ,Analytics ,big data ,Public transport ,Pandemic ,transport analytics ,Covid-19 ,business ,Reboot - Abstract
Dealing with emergencies is never an easy task. Coping with the Covid-19 emergency was and still is an incredibly tough and unprecedent challenge for mankind, not only from a healthy point of view, but also from a socio-economic point of view, where a key role will be played by a reliable and sustainable transport of people and goods. Professional and researchers from all disciplines have been required to adapt their models, methods and tools to support decision makers in coronavirus emergency days. This paper reports the experience of the authors for the analysis of the Rome mobility system to estimate the impacts of the progressive lockdown imposed by the government. It focuses on data available for monitoring, which have been used to carry out transport analytics both for private and public transport. Such analytics have been used for planning the reboot of the transport system to be ready for the post Covid-19 era.
- Published
- 2020
115. Advances in Ku-Band GaN Single Chip Front End for Space SARs: From System Specifications to Technology Selection
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Francesco Scappaviva, Gianni Bosi, Andrea Biondi, Sara D’Angelo, Luca Cariani, Valeria Vadalà, Antonio Raffo, Davide Resca, Elisa Cipriani, Giorgio Vannini, Scappaviva, F, Bosi, G, Biondi, A, D'Angelo, S, Cariani, L, Vadalà, V, Raffo, A, Resca, D, Cipriani, E, and Vannini, G
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small- and large-signal characterization ,low-noise amplifier (LNA) ,Computer Networks and Communications ,transmit/receive module (TRM) ,high-power amplifier (HPA) ,switch ,Hardware and Architecture ,Control and Systems Engineering ,single-chip front-end (SCFE) ,gallium nitride (GaN) ,Signal Processing ,ING-INF/01 - ELETTRONICA ,Electrical and Electronic Engineering - Abstract
In this paper, a single-chip front-end (SCFE) operating in Ku-band (12–17 GHz) is presented. It is designed exploiting a GaN on SiC technology featured by 150 nm gate length provided by UMS foundry. This MMIC integrates high power and low noise amplification functions enabled by a single-pole double-throw (SPDT) switch, occupying a total area of 20 mm2. The transmitting chain (Tx) presents a 39 dBm output power, a power added efficiency (PAE) higher than 30% and a 22 dB power gain. The receive path (Rx) offers a low noise figure (NF) lower than 2.8 dB with 25 dB of linear gain. The Rx port output power leakage is limited on chip to be below 15 dBm even at high compression levels. Finally, a complete characterization of the SCFE in the Rx and Tx modes is presented, also showing the measurement of the recovery time in the presence of large-signal interferences.
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- 2022
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116. Integration between activity-based demand models and multimodal assignment: Some empirical evidences
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Ernesto Cipriani, Andrea Gemma, Umberto Crisalli, Livia Mannini, Cipriani, E., Crisalli, U., Gemma, A., and Mannini, L.
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Sequence ,Operations research ,Computer science ,Transport policy ,Geography, Planning and Development ,Integration ,Transportation ,Crowding ,Multimodal assignment ,Urban Studies ,Real size ,Consistency (database systems) ,Modal ,Activity based models ,Convergence (routing) ,TRIPS architecture ,Activity based model ,Settore ICAR/05 ,Convergence - Abstract
Aiming at supporting decision makers in transport policy choices, transport models used for decades the trip-based approach for travel demand forecasts. This approach, despite suited to peak hours modelling where systematic trips are predominant, suffers the limits of not being related to the sequence of activities usually undertaken in real day-life. Differently, in the Activity Based Models (ABM) the travel demand is explicitly modelled as the result of individuals’ involvement in different activities in different times and locations. The use of such models is recommended when complex trip chains connected to the multiple daily activities that characterise today's life have to be taken into account, even if the integration with other sub-models (particularly with the assignment) within the whole transport modelling procedure has to be carefully considered. For this reason, this paper focuses on the integration between ABM and transport assignment by investigating the multimodal demand-supply interaction. Specifically, the consistency between ABM and assignment models is studied proposing a methodology that can be applied to large real size networks. It is based on a multimodal static equilibrium assignment, which is easy-to-use and less time consuming with respect to a Dynamic Traffic Assignment (DTA), allowing a better estimation of the modal splits between alternative transport modes. Such a model also considers (road) congestion and (transit) crowding phenomena, as well as the multimodal network performances are estimated by taking into account the interaction between different modes sharing the same network facilities. The goodness of the proposed approach is investigated through the convergence analysis of both the entire integration procedure and its individual components (ABM and assignment) for a better transport simulation in urban areas. The application to an urban multimodal network of real-size dimensions (Rome) is presented to show the promising results of this research.
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- 2020
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117. Velia. Fenomeni alluvionali e trasformazioni dell’abitato
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Luigi Cicala, Teresa Tescione, M. Cipriani, E. Greco, A. Salzano, C.I. Tornese, Cicala, Luigi, and Tescione, Teresa
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Elea, Velia, Archeologia, Urbanistica, Architettura domestica, Archeologia delle alluvioni, Cultura materiale - Abstract
The Southern Quarter of Velia represents a particularly stimulating case-study concerning the relationship between settlement and environment. The lower city, indeed, is affected, especially in the Imperial age, by a series of alluvial floods, that gradually modify the inhabited area layout, determining the walking surfaces aggradation and various rearrangement buildings interventions. Recent research data offers the first elements to discuss the impact of these events on the community and its resilience capacity. The ceramic assemblage from the sampled area returned data for the formation processes interpretation and chronological reconstruction of the context. The different approaches (quantitative, qualitative, chronological and spatial analysis) allowed to recognize the impact of the alluvial events on the stratigraphical sequence. The chrono-typological evaluation enabled a preliminary reconstruction of the Middle and Late Roman ceramic repertoires, a phase still not so known in Velia.
- Published
- 2022
118. Case studies of integration between activity-based demand models and multimodal assignment
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Ernesto Cipriani, V. Busillo, Andrea Gemma, Livia Mannini, Umberto Crisalli, Gemma, A., Mannini, L., Busillo, V., Cipriani, E., and Crisalli, U.
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Sequence ,business.industry ,Computer science ,Transport policy ,Economics, Econometrics and Finance (miscellaneous) ,Simulation modeling ,Rome ,Integration ,Transportation ,computer.software_genre ,Crowding ,Multimodal assignment ,Consistency (database systems) ,Real size ,Activity based models ,Public transport ,Activity based model ,Data mining ,Settore ICAR/05 ,business ,Convergence ,computer ,Doha - Abstract
Aiming at supporting decision makers in transport policy choices in an increasingly complex sequence of activities of our real day-life, this paper investigates the integration between Activity Based Model (ABM) and transport assignment by focusing on the multimodal demand-supply interaction to be used in more advanced simulation models. The consistency between ABM and assignment models is studied proposing a methodology that can be applied to large real size networks. A new formalization of integration of ABM with multimodal assignment is proposed, oriented to an easy-to-use and computationally faster application. The interaction between different modes sharing the same network facilities is considered, as well as crowding (public transport) and congestion (road) phenomena. The application to different real case studies in Qatar and in Rome are presented to show the promising results of the proposed approach for a better transport simulation in urban areas.
- Published
- 2022
119. Il Santuario di Apollo Pizio a Cirene nel contesto storico-politico e socio-economico della polis in età greca. Tra urbanistica e architettura, tra culti pubblici e culti privati
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Serenella Ensoli, Serenella Ensoli, M. Cipriani, E. Greco, A. Pontrandolfo, and Ensoli, Serenella
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During the Greek period the Cyrenean Sanctuary of Apollo Pizius has been expanding to the E (Garden of Aphrodite), to the S (Spring Terrace, previously external to the temenos) and to the W (Alsos of Apollo and Theatre). During the age of Battiades a unitary project took place in order to monumentalize the sacred area on the model of the Panhellenic sanctuaries of Olympia, Delphi and Delos. With the fall of the monarchy, works of urban impact were realized with the aim of delimiting and rationally organizing the sacred space. In this phase, the lower strata of the community gain power, emphasizing cults previously not documented by monumental remains. In the 4th century BC the temenos reaches his final limits, but with a gradual loss of the previous organicity, due to the construction of new sacred, celebratory and utilitarian buildings, which reflect the new needs of the ruling class. In the Hellenistic period, the structure of the sanctuary underwent radical transformations, with a multiplication of the monuments linked to the further increase in the political significance of the cult of Apollo, connected with the post-Alexandrian dynastic ideology, according to a polycentric conception of cultural activities that will characterize the complex until the end of his life.
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- 2022
120. Analysis and monitoring of post-COVID mobility demand in Rome resulting from the adoption of sustainable mobility measures
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Andrea Gemma, Stefano Saracchi, Ernesto Cipriani, Livia Mannini, Natalia Isaenko, Gaetano Fusco, Chiara Colombaroni, Vito Busillo, Stefano Carrese, Umberto Crisalli, Marco Petrelli, Carrese, S., Cipriani, E., Colombaroni, C., Crisalli, U., Fusco, G., Gemma, A., Isaenko, N., Mannini, L., Petrelli, M., Busillo, V., and Saracchi, S.
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Transportation planning ,Service (systems architecture) ,Data collection ,Social distancing ,Traffic data analytics ,business.industry ,Distancing ,Geography, Planning and Development ,Transportation ,Interpersonal communication ,Covid-19 pandemic ,Public transport access control ,Bus transit ,public transport access control ,social distancing ,traffic data analytics ,Transport engineering ,Public transport ,Settore ICAR/05 ,business ,Transit (satellite) - Abstract
The paper describes research activities of monitoring, modeling, and planning of people mobility in Rome during the Covid-19 epidemic period from March to June 2020. The results of data collection for different transport modes (walking, bicycle, car, and transit) are presented and analyzed. A specific focus is provided for the subway mass transit, where 1 m interpersonal distancing is required to prevent the risks for Covid-19 contagion together with the use of masks and gloves. A transport system model has been calibrated on the data collected during the lockdown period –when people's behavior significantly changed because of smart-working adoption and contagion fear– and was applied to predict future mobility scenarios under different assumptions on economic activities restarting. Based on the estimations of passenger loading, a timing policy that differentiates the opening hours of the shops depending on their commercial category was implemented, and an additional bus transit service was introduced to avoid incompatible loads of the subway lines with the required interpersonal distancing.
- Published
- 2021
121. Traffic demand estimation using path information from Bluetooth data
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Ernesto Cipriani, Livia Mannini, Stefano Carrese, Umberto Crisalli, Andrea Gemma, Cipriani, E., Gemma, A., Mannini, L., Carrese, S., and Crisalli, U.
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Estimation ,Exploit ,Computer science ,Real-time computing ,Demand estimation ,Path Information ,Transportation ,Context (language use) ,Plan (drawing) ,Management Science and Operations Research ,Analytical model ,law.invention ,Bluetooth ,Bluetooth Data ,Demand Estimation ,law ,Automotive Engineering ,Path (graph theory) ,Point (geometry) ,Analytical models ,Settore ICAR/05 ,Civil and Structural Engineering - Abstract
Recent advances in technology have made available numerous new monitoring systems that collect updated traffic measurements both in fixed locations and over specific corridors or paths. Such recent technological developments point to challenging and promising opportunities for Origin-Destination (OD) traffic demand estimation and forecast. Therefore, the aim of this paper is to study how to exploit available information detected by new monitoring devices in the estimation of traffic demand. Starting from the formulation proposed by Spiess (1987, 1990), in this paper a new method to estimate the traffic demand by means of Bluetooth data is proposed. It explores inherent properties of this information in an off-line (and static) context, where mathematical formulation of the estimation problem can be derived. The effectiveness of the proposed method has been investigated in an extensive plan of experiments carried out both on test networks and on a study network consisting in a part of the city of Rome, Italy, obtaining promising results in both applications.
- Published
- 2021
122. On Transport Monitoring and Forecasting during COVID-19 Pandemic in Rome
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Stefano Brinchi, Natalia Isaenko, Andrea Gemma, Gaetano Fusco, Chiara Colombaroni, Ernesto Cipriani, Sergio Maria Patella, Umberto Crisalli, Stefano Carrese, Marco Petrelli, Livia Mannini, Brinchi, S., Carrese, S., Cipriani, E., Colombaroni, C., Crisalli, U., Fusco, G., Gemma, A., Isaenko, N., Mannini, L., Patella, S. M., and Petrelli, M.
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Government ,Process management ,Coronavirus disease 2019 (COVID-19) ,business.industry ,transport modelling ,Mobility system ,Social distance ,General Engineering ,prediction ,K4011-4343 ,Transportation and communication ,Computer Science Applications ,New normal ,Covid-19 ,transport analytics ,transport monitoring ,predictions ,transport analytic ,Analytics ,Public transport ,Pandemic ,Business ,Settore ICAR/05 - Abstract
This paper presents the results of a study on the Rome mobility system aiming at estimating the impacts of the progressive lockdown, imposed by the government, due to the Covid-19 pandemic as well as to support decision makers in planning the transport system for the restart towards a post-Covid “new normal”. The analysis of data obtained by the transport monitoring system has been fundamental for both investigating effects of the lockdown and feeding transport models to predict the impacts on future actions. At first, the paper focuses on the so-called transport analytics, by describing mobility trends for the multimodal transportation system of Rome. Then, the results of the simulated scenarios to design public transport services, able to ensure passengers social distancing required in the first post-Covid months, are presented and discussed.
- Published
- 2020
123. Supply characteristics and membership choice in round-trip and free-floating carsharing systems
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Francesco Viti, Ernesto Cipriani, Giulio Giorgione, Carolina Cisterna, MT-ITS 2019 Conference, Cisterna, C., Giorgione, G., Cipriani, E., and Viti, F.
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Scheme (programming language) ,Service (business) ,supply ,Relation (database) ,business.industry ,membership ,Rigid structure ,Synthetic population ,Transport engineering ,Renting ,Wide area ,carsharing ,business ,computer ,Binary logit model ,computer.programming_language - Abstract
Carsharing is a car rental system in which members have access to a fleet of cars on a relatively short time basis. Several different types of car-sharing services have been developed such as round-Trip and free-floating: The first one is characterized by a more rigid structure because of its station-based nature, the second tends to be more flexible since a customer can pick up and drop off the car in any public parking inside a wide area. Being a member is the first step users have to take to use this sharing service. This study focuses on the analysis of supply attributes directly linked to territorial characteristics such as parking availability, parking price, distance from the city center, users' trip chain in relation with location of activities and their impact on the membership choice. By using a binary logit model, and a synthetic population of the city of Berlin representing members of both the round-Trip and the free-floating service, and through a sensitivity analysis, the study shows how membership is sensible to some of these attributes identifying which supply characteristics impact the user membership choice. Results suggest there are two typical membership profiles and the attributes that lead the choice are different. While a round-Trip carsharing member is more willing to drive towards more than one destination and does not always have his/her own car available, the free-floating carsharing member is more apt to use a point-To-point trip scheme driving for more than 15 minutes using the service as substitute of the owned car.
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- 2019
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124. Hybrid choice model to analyze electric car sharing demand in a university community
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Stefano Carrese, Leonardo Zamberlan, Tommaso Giacchetti, Eleonora Sottile, Ernesto Cipriani, MT-ITS 2019 Conference, Carrese, S., Cipriani, E., Giacchetti, T., Sottile, E., and Zamberlan, L.
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Flexibility (engineering) ,Service (business) ,business.product_category ,electric vehicle ,Plan (drawing) ,Environmental economics ,car sharing ,Behavioral modeling ,behavioral model ,Order (business) ,Component (UML) ,Electric vehicle ,TRIPS architecture ,Business ,sharing mobility - Abstract
Sharing Mobility is characterized by a high digital component able to supply customers with a considerable level of flexibility in urban trips. The study was conducted focusing on the E-go car sharing project, promoted by University of Roma Tre and Enel Energia S.p.A. E-go is an university electric car sharing system. The paper provides a double contribution to the research activity on sharing mobility: i) the exploration of the electric car sharing potential demand among students; ii) the implementation of an Hybrid Choice Model to analyze the role of the pro-environmental attitude on the users’ willingness to use car sharing. The analysis has been based on the data collected in a survey among the potential users of the e-go car sharing service. One of the first findings of the study is that the pro-environmental attitude doesn’t significantly influence the choice of the users. The authors suggest to the car sharing operators and to the policy makers to take in consideration the results of the study in order to plan promotional strategies and to develop policies aiming at supporting the spread of this service.
- Published
- 2019
125. Identità e mondo globalizzato: contesti funerari tra Epiro, Magna Grecia e Sicilia in età ellenistica
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G. Lepore, M. Cipriani, E. Greco, A. Pontrandolfo, M. Scafuro, and G. Lepore
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Il contributo propone unu percorso tra i vari gradi della comunicazione dell'identità del defunto all'interno dei contesti necropolari. Il tema trattato è quello della ricerca dei possibili "indicatori archeologici" dell'identità etnica e del senso di appartenenza - Published
- 2019
126. Un Kyathos attico a f.r. da una tomba di Valle Trebba, Spina. Contesto e funzione di una forma a cavallo tra mondo etrusco e mondo greco
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andrea gaucci, delphine tonglet, M. Cipriani, E. Greco, A. Pontrandolfo, M.L. Rizzo, M. Scafuro, andrea gaucci, and delphine tonglet
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mobilità ,Spina ,Ceramica attica ,Etruschi - Abstract
Tomb 713 from the Valle Trebba necropolis of Spina is a female burial belonging to a group of graves which stands out by the exceptional character of the grave goods and the specific ideological choices expressed by the objects. Within the Tomb, the presence of a red-figured kyathos with unique characteristics leads to a study of its hypothetical manufacturing process and its functional, cultural and ideological implications in the burial context.
- Published
- 2019
127. Strategies and Measures for Sustainable Urban Transport Systems
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Eleonora Meta, Ernesto Cipriani, Veronica Sgarra, Luca Persia, Persia, L., Cipriani, E., Sgarra, V., and Meta, E.
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Computer science ,Transportation ,010501 environmental sciences ,01 natural sciences ,Hierarchical database model ,0502 economics and business ,benchmarking ,Set (psychology) ,0105 earth and related environmental sciences ,Strategic planning ,Sustainable development ,050210 logistics & transportation ,strategie ,business.industry ,05 social sciences ,Environmental resource management ,enviroment ,road ,strategies ,sustainability ,Benchmarking ,Environmental economics ,Policy analysis ,Metropolitan area ,Sustainability ,business - Abstract
Increasing sustainability of urban transport systems is a crucial objective of all strategic plans both at national and European level. Different strategies and measures can be adopted to improve the efficiency of transport systems, according to a large set of factors that can affect the results of the implemented actions. A comprehensive study has been carried out in order to define a methodology able to define effective and efficient strategies and measures, allowing to increase the sustainability level of different kinds of cities, from small-medium sized to large metropolitan areas. The methodology has been tested on a group of 50 Italian cities, whose characteristics have been analysed through an initial set of more than 200 indicators. Three main groups of indicators have been taken into account: State indicators, Sustainability indicators, Policy indicators. The main aim has been to identify existing relationships between Sustainability and Policy indicators for cities showing commonalities in terms of State indicators. A correlation analysis allowed to identify 53 relevant indicators from the initial set of 200, while a cluster analysis, based on a hierarchical model, allowed to group the cities into five different groups, according to their population size and density. Correlations between relevant indicators have also been analysed within each group, while linear regression models have allowed to describe some functional relations between Policy and Sustainability indicators. A benchmarking exercise has allowed to identify strategies and measures adopted by the best performers within each group, hence defining possible paths to a better sustainability level for the remaining cities. Finally, recommendations for a correct urban mobility planning procedures have been produced.
- Published
- 2016
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128. Extended operation of class-F power amplifiers using input waveform engineering
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Elisa Cipriani, Gianni Bosi, Giorgio Vannini, Valeria Vadala, Antonio Raffo, Paolo Colantonio, Franco Giannini, Cipriani, E, Colantonio, P, Giannini, F, Raffo, A, Vadala, V, Bosi, G, and Vannini, G
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power amplifiers, harmonics, measurements, load pull, waveform engineering ,Computer science ,power amplifier ,Amplifier ,020206 networking & telecommunications ,02 engineering and technology ,High-electron-mobility transistor ,Settore ING-INF/01 - Elettronica ,NO ,Power (physics) ,Harmonic analysis ,harmonic ,Logic gate ,harmonics ,0202 electrical engineering, electronic engineering, information engineering ,Electronic engineering ,Harmonic ,Waveform ,measurement ,Radio frequency ,power amplifiers ,measurements ,load pull ,waveform engineering - Abstract
Starting from the mathematical bases of waveform engineering, this contribution demonstrates the effectiveness of class-F power amplifier design in different bias conditions, provided the correct harmonic content is presented at the input. To validate the theoretical assumptions, low-frequency multi-harmonic load-pull measurements are carried out on a 1-mm gate periphery GaN HEMT, giving an experimental proof of the validity of the extended harmonic manipulation approach.
- Published
- 2017
129. On-Street Parking Search Time Estimation Using FCD Data
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Andrea Gemma, G. Vaccaro, Ernesto Cipriani, Umberto Crisalli, Livia Mannini, L. Mannini, E. Cipriani, U. Crisalli, A. Gemma, G.Vaccaro, Mannini, L., Cipriani, E., Crisalli, U., Gemma, A., and Vaccaro, G.
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User information ,050210 logistics & transportation ,Computer science ,05 social sciences ,Real-time computing ,on-street parking ,modeling ,Transportation ,010501 environmental sciences ,Adaptive routing ,FCD data ,01 natural sciences ,Settore ICAR/05 - Trasporti ,car travel time ,parking search time ,Time estimation ,0502 economics and business ,Spiral (railway) ,0105 earth and related environmental sciences - Abstract
This paper focuses on modelling on-street parking search time by using FCD data coming from probe vehicles. It is based on data detected by probe vehicles, which allow to identify the typical spiral around the destination that vehicles perform in the final part of the trip to find a parking place. The proposed model is suitable to be used either in real-time to support user information and dynamic routing, or off-line for a better assessment of transport plans. A real-size application to the city of Rome is presented to show the promising results obtained for the estimation of parking search time in urban areas.
- Published
- 2017
130. Empowering GaN HEMT models: The gateway for power amplifier design
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Crupi, Giovanni, Vadalà, Valeria, Colantonio, Paolo, Cipriani, Elisa, Caddemi, Alina, Vannini, Giorgio, Schreurs, Dominique M. M. P., Crupi, G, Vadala', V, Colantonio, P, Cipriani, E, Caddemi, A, Vannini, G, and Schreurs, D
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Equivalent circuit ,GaN HEMT ,Equivalent circuit, GaN HEMT, Microwave measurements, Power amplifier design, Modeling and Simulation, Computer Science Applications1707 Computer Vision and Pattern Recognition, Electrical and Electronic Engineering ,Power amplifier design ,Settore ING-INF/01 - Elettronica ,Microwave measurement ,NO - Abstract
The purpose of this invited paper is to give readers a comprehensive and critical overview on how to extract equivalent-circuit models for GaN HEMTs, which are the preferred devices for high-power high-frequency applications. This overview is meant to provide a practical modeling know-how for this advanced type of transistor, in order to support its development for improving device technology and circuit design. With the aim to broaden knowledge to empower models, experimental results are presented as illustrative examples of the most crucial challenges faced by the microwave engineers in modeling high-power GaN HEMTs. All the relevant aspects are covered, going from linear (also noise) to nonlinear models. The analysis is mainly focused on the modeling of distinctive peculiarities of GaN HEMTs. Particular attention is paid to study the importance of accurately modeling the kink effect in the output reflection coefficient, because of the relatively high transconductance, the peak in the magnitude of the short circuit current-gain, because of the relatively large intrinsic capacitances, and the low-frequency dispersion, because of trapping and thermal effects. Furthermore, to emphasize the key role of accurate device models for a successful circuit design, a practical example of power amplifier is discussed.
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- 2017
131. Theoretical consideration on harmonic manipulated amplifiers based on experimental data
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Teresa M. Martin-Guerrero, Paolo Colantonio, Franco Giannini, Valeria Vadala, Elisa Cipriani, Gianni Bosi, Giorgio Vannini, Antonio Raffo, Raffo, A, Colantonio, P, Cipriani, E, Vadalà, V, Bosi, G, Martin Guerrero, T, Vannini, G, and Giannini, F
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Computer science ,integrated circuit measurement ,FET, harmonic manipulation, integrated circuit measurements, microwave power amplifier, semiconductor device measurements ,High-electron-mobility transistor ,Settore ING-INF/01 - Elettronica ,microwave power amplifier ,NO ,law.invention ,Microwave power amplifier ,Harmonic analysis ,Harmonic manipulation ,law ,Integrated circuit measurement ,harmonic manipulation ,Electronic engineering ,Telecomunicaciones - Congresos ,Semiconductor device measurement ,FET ,integrated circuit measurements ,Semiconductor device measurements ,Plane (geometry) ,Amplifier ,Transistor ,Experimental data ,Current sense amplifier ,Harmonic ,ING-INF/01 - ELETTRONICA - Abstract
This contribution aims at the experimental confirmation of the advantages of the harmonic manipulation theory, using a low-frequency low-cost characterization setup. A 0.5-μm 10x100-μm (1-mm gate periphery) GaN HEMT has been characterized synthesizing at the current-generator plane different load conditions, realizing tuned-load and Class-F operation. The measurements clearly demonstrate the importance of by synthesizing the required loads at the correct reference plane, giving an experimental proof of the performance predicted by theoretical analysis. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
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- 2015
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132. T/R modules front-end integration in GaN technology
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Mirko Palomba, Natanael Ayllon, Paolo Colantonio, Elisa Cipriani, Corrado Florian, Sergio Colangeli, Ernesto Limiti, Walter Ciccognani, Marco Pirola, Limiti, E., Ciccognani, W., Cipriani, E., Colangeli, S., Colantonio, P., Palomba, M., Florian, C., Pirola, M., and Ayllon, N.
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Engineering ,noise ,Computer Networks and Communications ,C band ,Front-End ,GaN ,single-chip ,T/R module ,Gallium nitride ,switches ,Noise figure ,Noise (electronics) ,Settore ING-INF/01 - Elettronica ,Front and back ends ,chemistry.chemical_compound ,Front-end ,Single-chip ,Electronic engineering ,Power output ,Electrical and Electronic Engineering ,Read-only memory ,business.industry ,Electrical engineering ,chemistry ,business ,Realization (systems) - Abstract
The present contribution summarizes the activities performed towards the realization of a Single-Chip Front-End (SCFE) operating in C Band, integrating the High Power, Low Noise amplification and switching functionalities to be provided in modern T/R modules' Front-Ends for space SAR applications. The technologies adopted in this project are provided by United Monolithic Semiconductors (UMS) and Selex Electronic Systems (SLX), the GH25-10 0.25 µm gate length and the GaN technology featured by 0.5 µm gate length for UMS and SLX respectively. At the completion of the design phase two SCFEs have been designed in the two technologies, each in two slightly different versions, featured by state-of-the-art performance. In particular, in Tx-mode, both are featured by approximately 40 W power output, with 36 dB large-signal gain and 38 % / 27 % PAE for UMS and SLX versions respectively, while in Rx-mode 2.5 dB noise figure resulted, with robust operation. The two dies are featured by 6.9 × 5.4 mm2 and 7.28 × 5.40 mm2 for UMS and SLX versions respectively.
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- 2015
133. C-band power amplifier design based on low-frequency waveform engineering
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Franco Giannini, Elisa Cipriani, Valeria Vadala, Gianni Bosi, Giorgio Vannini, Antonio Raffo, Paolo Colantonio, Cipriani, E, Colantonio, P, Giannini, F, Bosi, G, Raffo, A, Vadalà, V, and Vannini, G
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Engineering ,power amplifier ,Settore ING-INF/01 - Elettronica ,law.invention ,NO ,Hardware_GENERAL ,law ,Hardware_INTEGRATEDCIRCUITS ,Electronic engineering ,characterizaion ,load pull ,measurements ,power amplifiers ,Linear amplifier ,Waveform ,Direct-coupled amplifier ,Measurement ,business.industry ,Amplifier ,RF power amplifier ,Transistor ,Load pull ,Electrical engineering ,Power bandwidth ,ING-INF/01 - ELETTRONICA ,business - Abstract
In this work, the design of a C-band class-AB power amplifier based on the waveform engineering approach is presented. The design leverages the low-frequency characterization of the transistor to obtain the prediction of its optimum operating condition. An exhaustive validation of the realized amplifier fully validates the proposed design technique.
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- 2015
134. A procedure for urban route travel time forecast based on advanced traffic data: Case study of Rome
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Stefano Brinchi, Stefano Gori, Livia Mannini, Ernesto Cipriani, E. Cipriani, S. Gori, L. Mannini, S. Brinchi, Cipriani, E., Gori, S., Mannini, L., and Brinchi, Stefano
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Transport engineering ,Travel time ,Computer science ,Mechanical Engineering ,Automotive Engineering ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,Computer Science Applications1707 Computer Vision and Pattern Recognition ,Current (fluid) - Abstract
In this paper, authors report a procedure to forecast the route travel time, based on different advanced traffic data, both historical and current. The procedure is articulated in two main steps: the first consists in apportioning current route travel time among the links based on historical Floating Car Data; in second step, the obtained link travel times are combined with the current loop detectors data through the measurement data fusion technique; moreover, the Extended Kalman Filter (EKF) correction is applied to a second order traffic model, in order to forecast the link speeds and consequently link and route travel times. Real applications of the proposed procedure concerning both a signalized route of Lungotevere and 6.5 kilometers urban freeway with 14 on/off-ramps in Rome are reported. The results of the forecasted route travel time show a good accuracy until the detected data used to correct the estimation are coherent and the input data, such as flows on ramps, are reliable. The results of the link speeds in terms of RMSE and RME with respect to the data detected by the loop sensors seem to be accurate, however further development will deal with the comparison to the other existing methods. Finally, the results underline, as it is well known, the need of real and reliable data in order to provide a good forecast.
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- 2014
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135. A framework for the benchmarking of OD estimation and prediction algorithms
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Antoniou C, Ciuffo B, Casas J, Barcelò J, CIPRIANI, ERNESTO, Montero L, Djukic T, Marzano V, NIGRO, Marialisa, Bullejos M, Perarnau J, Breen M, Punzo V, Toledo T., Antoniou, C., Ciuffo, B., Montero, L., Casas, J., Barcelo, J., Cipriani, E., Djukic, T., Marzano, V., Nigro, M., Bullejos, M., Perarnau, J., Breen, M., Punzo, Vincenzo, Toledo, T., Antoniou, C, Ciuffo, B, Casas, J, Barcelò, J, Cipriani, Ernesto, Montero, L, Djukic, T, Marzano, V, Nigro, Marialisa, Bullejos, M, Perarnau, J, Breen, M, and Punzo, V
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traffic modeling ,Origin-Destination (OD) estimation - Abstract
In this research we describe the development of a common evaluation and benchmarking platform that has been developed within the framework of the European Union COST Action MULTITUDE. The main goal of this platform is to provide a testbed in which a number of algorithms can be implemented and tested under the same conditions. The objective is not to conclude that one approach is “best”, but to provide a support comparison in a variety of settings and conditions in order to help determine the particular situations and conditions under which one approach might behave more favorably than another. The design of the platform is presented, along with a detailed experimental design for the application of different OD estimation algorithms. The considered algorithms are then presented, along with a demonstration of the extensibility of the presented framework to accommodate additional data sources. The presented results demonstrate that the developed framework is capable of supporting the development, application and testing of a wide range of algorithms. First, both off-line/planning level algorithms (like the Bilevel-DUE) and on-line algorithms (like that SPSA AD-PI and the KFX2) are presented.
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- 2014
136. Evaluation of FET performance and restrictions by low-frequency measurements
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Valeria Vadala, Paolo Colantonio, Elisa Cipriani, Claudio Lanzieri, Andrea Nalli, Gianni Basi, A. Pantellini, Giorgio Vannini, Antonio Raffo, Franco Giannini, Vadalà, V, Raffo, A, Colantonio, P, Cipriani, E, Giannini, F, Lanzieri, C, Pantellini, A, Nalli, A, Bosi, G, and Vannini, G
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Semiconductor device measurement ,Computer science ,System of measurement ,Transistor ,GaN HEMT ,High-electron-mobility transistor ,Low frequency ,Settore ING-INF/01 - Elettronica ,law.invention ,Electricity generation ,law ,Logic gate ,Electronic engineering ,ING-INF/01 - ELETTRONICA ,microwave amplifier - Abstract
In this paper a characterization technique for the evaluation of transistor performance and restrictions is presented, based on a simple and low-cost measurement system. Experimental examples, carried out on a 0.5 × 1000 μm2GaN HEMT, are reported. The validity of the proposed approach is demonstrated by comparing the results with the ones obtained by means of commonly adopted measurement setups.
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- 2014
137. Airport noise charges and local communities: evaluation and implications on commercial flights
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GUALANDI, NICOLA, MANTECCHINI, LUCA, PAGANELLI, FILIPPO, Umberto Crisalli, Ernesto Cipriani e Gaetano Fusco, N. Gualandi, L. Mantecchini, and F. Paganelli
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noise level ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,ENVIRONMENTAL TAXATION ,AIR TRANSPORTATION - Abstract
There have always been arguments between airports and local communities because of the aeronautical noise. In fact, this is a factor that, if not properly managed, can severely cut down the development of air traffic in an airport with direct repercussions on the economic and territorial system. Nevertheless, particularly in the last decade, the critical issues relating to the impact of aeronautical noise on airport operations have greatly reduced thanks to the technological improvements in the design of aircrafts. However, the reduction of the noise emission during a single event does not make the issue of the airports’ location less important. This is the case of regional airports that have recently experimented a large traffic increase due to the development of low-cost traffic. It is now clear that the problem can not be reduced to its mere technological aspects, but it ought to be dealt with the involvement of the various entities in order to mitigate the impacts and adequately compensate the damages to local communities. Typically, there are two possible countermeasures to mitigate the effects of aircraft noise: operational measures, based on the application of technological and organizational devices and market-based measures. For example, the application of noise taxes or noise charges aiming at compensating the negative externalities generated by airport operations is becoming increasingly widespread. This paper discusses a methodology for the application of noise taxes based on the actual noise of aircraft operating into an airport.
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- 2013
138. Air quality model validation in urban area: a new approach using a wireless pervasive sensor system
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Bell, MC, Galatioto, F, Ristagno, SS, MIGLIORE, Marco, Crisalli, U., Cipriani, E, Fusco, G, Bell, MC, Galatioto, F, Migliore, M, and Ristagno, SS
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Settore ICAR/05 - Trasporti ,Air quality, taffic flow, congestion - Abstract
This paper describes the implementation in Palermo of a new approach developed at Newcastle University (UK), in the context of the MESSAGE project (Mobile Environmental Sensing System Across Grid Environments), using a novel inexpensive pervasive sensor system. The new system infrastructure shows how additional data from the new environmental sensors, namely “mote” can improve the assessment of the impact of traffic and congestion on air quality. After an evaluation and validation process of the sensors against the precision system (City Council Environmental Cabin) the sensors where deployed in Palermo and using the data, actual traffic flows and pedestrian traffic light information (all synchronised at one minute resolution), a simulation model was set up to predict air quality, and potentially noise and exposure levels for pedestrian. The proposed approach has been evaluated using a case study area in Palermo, namely a street canyon, in Libertà Avenue. Analysis, calibration and validation of data from two static pervasive sensors, will be presented in this paper. Next the process by which the traffic characteristics (fleet composition, flow, queue length) collected over two months survey were used to validate parameters of the AIMSUN traffic simulation model (flows, queues, congestion states) will be shown. The validated microsimulation model subsequently was used to predict tailpipe emissions taking into account the traffic flow regimes (free flow, unstable and congested) and pollution concentrations which were estimated within the street canyon using the OSPM (Operational Street Pollution Model) model.These estimates will be compared with the pervasive sensor measurements of air pollution, CO, Carbon Monoxide and NO2, Nitrogen dioxide. Results presented in this paper will highlight the benefits of pervasive sensors in the model validation and how they can compliment legacy systems through their flexibility in covering detection gaps in existing urban networks. Moreover, the proposed approach will have the capacity to assess the changes caused in previously unmonitored areas, resulting in more realistic assessments of the impacts of transport policies and strategies. Finally, an evaluation of emissions impact from new pedestrian traffic light scenarios is presented.
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- 2013
139. Prevalence of peripheral artery disease by abnormal ankle-brachial index in atrial fibrillation: implications for risk and therapy
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Violi, Francesco, Daví, Giovanni, Hiatt, William, Lip, Gregory Y. H., Corazza, Gino R., Perticone, Francesco, Proietti, Marco, Pignatelli, Pasquale, Vestri, Anna R., Basili, Stefania, Desideri, ARAPACIS Study Investigators Alessandri Cesare (Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, G., Sapienza-Università di Roma), Serviddio Gaetano (Department of Medical and Surgical Sciences, University of Foggia), Fascetti Stefano (UOC Medicina Generale, USL 12 Viareggio, Toscana), Serra, Pietro, Palange Paolo(UOC Medicina Interna, I, Dipartimento di Sanità Pubblica, e Malattie Infettive, Greco, Eleonora, Bruno Graziella (Medicina, 3, Department of Medical Sciences, Città della Salute e della Scienza, A. O., University of Turin), Averna, Maurizio, Giammanco Antonina (Dipartimento Biomedico di Medicina Interna, e Specialistica (DIBIMIS), Università di Palermo), Sposito Pietro (Azienda Ospedaliera Ospedali Riuniti Papardo Piemonte, Messina), De Cristofaro Raimondo, De Gennaro Leonardo(Istituto di Medicina Interna, e Geriatria, Centro Emostasi, e Trombosi, Gemelli, Policlinico A., Roma), Loria, Paola, Pellegrini Elisa(Medicina Interna ad Indirizzo Metabolico, – NOCSAE Baggiovara, Department of Internal Medicine, Endocrinology, Metabolism and Geriatrics, Università degli Studi di Modena, e Reggio Emilia), Cominacini, Luciano, Mozzini Chiara (Dipartimento di Medicina, Sezione di Medicina Interna, D, Università di Verona), Sprovieri, Mario, Spagnuolo Vitaliano (UOC Medicina d'Urgenza, e PS, Stabilimento Ospedaliero dell'Annunziata, Cosenza), Cerqua Giannantonio (UOC Medicina Interna per l'Urgenza, S Giovanni Addolorata, Ao, Cerasola Giovanni, Mulé Giuseppe (Università degli Studi di Palermo), Barbagallo, Mario, Lo Sciuto Salvatore, Monteverde Alfredo(UOC di Geriatria, e Lungodegenza, Azienda Ospedaliera Universitaria Policlinico, Aoup, Palermo), Saitta, Antonino, Lo Gullo Alberto (UOC Medicina Interna, Università di Messina), Malatino, Lorenzo, Cilia Chiara (Clinica Medica, Ospedale, Cannizzaro, Università degli Studi di Catania), Licata, Giuseppe, Tuttolomondo, Antonino, Conigliaro Roberta (UOC Medicina Interna, e Cardioangiologia, Dipartimento Biomedico di Medicina Interna, e Specialistica, Università degli Studi di Palermo), Pinto, Antonio, Di Raimondo Domenico (UOC Medicina Vascolare, Dipartimento Biomedico di Medicina Interna e Specialistica, (Di. Bi. M. I. S. )., Signorelli, Santo, Anzaldi Massimiliano (Dipartimento di Medicina Interna, e Patologia, Università degli studi di Catania), De Palma Daniela, Galderisi, Maurizio, Cudemo Giuseppe (Dipartimento di Medicina Clinica, e Sperimentale, AUP Federico II di Napoli), Galletti, Ferruccio, Fazio Valeria(Dipartimento di Medicina Clinica, e Chirurgia, Università di Napoli Federico II), De Luca Nicola, Meccariello Alfonso (Centro Ipertensione, AUO Federico II, Napoli), Caputo, Dario, De Donato Maria Teresa (UO Medicina Interna, Azienda Ospedaliera Universitaria San Giovanni di Dio, e Ruggi D'Aragona, Salerno), Iannuzi, Arcangelo, Bresciani Alessandro (Divisione di Medicina Interna, Cardarelli, Osp. A., Giunta, Riccardo, Cimini Claudia (V Divisione Medicina Interna ed Immunoallergologia, Policlinico, Sun, Utili, Riccardo, Durante Mangoni Emanuele, Agrusta Federica (Medicina Infettivologica, e dei Trapianti, Monaldi, Ao, Sun, Napoli), Adinolfi Luigi, E., Sellitto, Cristiana, Restivo Luciano (Medicina Interna, Seconda Università di Napoli, Ospedale di Marcianise), Bellis, Paolo, Tirelli Paolo (UOC Medicina Interna e di Urgenza, e Pronto Soccorso, del Loreto Nuovo, P. O. S. M., Loreto, Mare), Sacerdoti, David, Pesce Paola (Clinica Medica, 5, Dipartimento di Medicina DIMED, Università degli Studi di Padova), Vanni Dino (UO Medicina Interna Arezzo, Ospedale San Donato, Azienda USL, 8 Arezzo), Iuliano, Luigi, Ciacciarelli, Marco, Pacelli Antonio (Department of Medico-Surgical Sciences and Biotechnology, Vascular Biology, Mass Spectrometry Lab, Sapienza-University of Rome), Palazzuoli Alberto (Sezione Cardiologia, Dipartimento di Medicina Interna, e Malattie Metaboliche, Università di Siena, Ospedale Le Scotte), Cacciafesta, Mauro, Gueli Nicola (UOC di Medicina Geriatrica, e Riabilitazione, Sapienza- Università di Roma, Capeci, William, Tarquinio, Nicola, Pellegrini Francesco (UO Medicina 'SS Benvenuto, e Rocco', Dipartimento di Medicina Interna, Asur, Marche, Area Vasta, n. 2., ex ZT 7), Vincentelli Giovanni Maria (UOS Breve Osservazione, Calibita 'Fatebenefratelli' Isola Tiberina, Ospedale S. G., Ravallese, Ferdinando, Santini Claudio (UOC Medicina Interna, Ospedale, Vannini, Letizia, Claudio, Petramala, Luigi, Zinnamosca Laura (UOD Ipertensione Secondaria, Dipartimento di Medicina Interna, e Specialità Mediche, Cilli, Mirella, Savoriti Claudio (UOC Medicina Interna F, e Malattie Metaboliche Dell'osso-Direttore Minisola Salvatore, Falaschi, Paolo, Martocchia, Antonio, Stefanelli Manuela (UO Geriatria, Andrea, Azienda Ospedaliera S., Facoltà di Medicina, e Psicologia, Marigliano, Vincenzo, Lo Iacono Cristina, Brusco Simona (Centro di Ricerca Interdipartimentale Scienze dell’Invecchiamento, Bertazzoni, Giuliano, Attalla El Halabieh Elias (UOC Medicina d’Urgenza, Dipartimento di Emergenza ed Accettazione, Paradiso, Michele, Lizzi Eugenio Maria, Timmi Stefano (Ospedale San Giovanni Battista, Ordine di Malta, Battisti Paola (Medicina Interna II, Ospedale San Giovanni-Addolorata, Cerci Sabina (UOC Medicina Interna, Ospedali Riuniti Frascati, Marino), Ciavolella Massimo (UOC Cardiologia-UTIC, Ospedale di Frascati, Di Veroli Claudio (Centro dell’Ipertensione Arteriosa e delle Malattie Metaboliche, e Renali, Casa di Cura 'San Domenico', Malci, Francesco, De Ciocchis Anita (UOC di Medicina Interna, Ospedale, ASL Roma, G, Subiaco), Abate, Damiano(Az., Castellino, Pietro, Curto, Irene, Vecchio Claudia (UOC Medicina Interna, Dipartimento di Scienze Mediche, e Pediatriche, Mannarino, Elmo, Pasqualini, Leonella, Fattori Chiara (Medicina Interna, Angiologia, e Malattie da Arteriosclerosi, Università degli Studi di Perugia), Pende, Aldo, Denegri, Andre, Artom Nathan (Clinica di Medicina Interna, 1, Università di Genova, San Martino - IST, IRCCS Az. Osp. Univ., Genova), Ricchio, Roberto, Fimognari Filippo Luca (UOC Geriatria, Azienda Ospedaliera di Cosenza, Alletto, Maurizio, Messina Simona (Unità Operativa di Medicina, Elia, Ospedale S., Caltanissetta), Sesti, Giorgio, Arturi, Franco, Grembiale Alessandro (Università degli Studi, UOC Medicina Interna, Policlinico Universitario 'Mater Domini'), Scarpino Paola Elisa, Carullo Giuseppe (Cattedra di Medicina Interna, UO Malattie Cardiovascolari, Campus Universitario di Germaneto, Università Magna Graecia di Catanzaro), Frugiuele, Pierluigi, Spagnuolo Vitaliano (UOC Medicina Interna, e Reumatologia, Stabilimento Ospedaliero Annunziata, Azienda Ospedaliera Cosenza), Battaglia Giuseppe (UO Lungodegenza, Serra San Bruno, S. O., ASP Vibo Valentia), Vidili, Gianpaolo, Atzori, Sebastiana, Delitala Giuseppe (Clinica Medica, Dipartimento di Medicina Clinica, e Sperimentale, Aou, Sassari), Davì, Giovanni, Angelucci, Ermanno, Sestili Simona (UOC di Clinica Medica, PO Clinicizzato di Chieti), Traisci, Giancarlo, De Feudis Lucrezia (UOC Medicina Interna, 2, PO di Pescara), Di Michele Dario, Fava Alessandra (UOC Medicina Interna, Asl, Teramo), Balsano, Clara, De Ciantis Pierpaolo (Dipartimento di Medicina Interna, e Sanità Pubblica, Università, dell'Aquila), Desideri, Giovambattista, Camerota Antonio (UOC Geriatria, e Lungodegenza Geriatrica, Dipartimento Medico ORM, Avezzano), Po, Migliacci, Rino, Medicina Interna, Porciello Giovanni (S. C., Ospedale della Valdichiana, Cortona, Usl, 8 Arezzo), Mezzetti Matteo (UOC Medicina Interna Ospedale del Casentino-Direttore Dr. Emilio Santoro, AUSL8 Arezzo), Gresele, Paolo, Vedovati, Cristina, Fierro Tiziana (Dipartimento di Medicina Interna, Sezione di Medicina Interna, e Cardiovascolare, Università di Perugia), Puccetti, Luca, Scarpini Francesca (Centro Aterosclerosi, Trombosi, e Coagulopatie, Università degli Studi di Siena, Azienda Ospedaliero-Universitaria Senese), Bertolotti, Marco, Mussi Chiara (UO Geriatria, Università degli Studi di Modena e Reggio Emilia), Dipartimento Integrato di Medicina Endocrinologia Metabolismo e Geriatria., Boddi, Maria, Savino, Andrea, Contri Silvia (Dipartimento di Area Critica Medico- Chirurgica, Università degli Studi di Firenze), Saller, Alois, Fabris Fabrizio (Clinica Medica1, Medicina Interna CLOPD, Departement of Medicine DIMED, University of Padova, Italy), Pesavento, Raffaele, Filippi, Lucia, Vedovetto Valentina (Dipartimento di Scienze Cardiologiche, Toraciche, e Vascolari, Clinica Medica, 2, Azienda Ospedaliera-Università di Padova), Puato Massimo (Clinica Medica IV, Dipartimento di Medicina, Azienda Ospedaliera Universitaria Padova, Padova), Fabris, Fabrizio, Treleani Martina (UOA Medicina, Policlinico, Universitario, Maselli, Monica, Corradin Maria Luisa, Giantin Valter (Clinica Geriatrica, Università di Padova), Semplicini Andrea (Medicina Interna, 1, Giovanni e Paolo, Ospedale SS., Venezia), Minuz, Pietro, Calabria, Stefano, Romano Simone (Sezione di Medicina Interna, C, Università di Verona, Aoui, Verona), Fantin, Francesco, Manica Angela (Dipartimento di Medicina, Sezione di Geriatria, Stockner, Ingrid, Pattis, Peter, Wiedermann), Gutmann Bernhard (Divisione di Medicina Interna-Direttore Prof. J., Ospedale centrale di Bolzano), Catena, Cristiana, Colussi GianLuca (Hypertension Unit and Division of Internal Medicine, Department of Experimental and Clinical Medical Science, University of Udine, Udine, Italy), Annoni, Giorgio, Bruni Adriana Antonella, Castagna Alberto (Clinica Geriatrica, Università degli Studi di Milano- Bicocca, Dipartimento di Scienze della Salute, AO San Gerardo, Monza), Spinelli Diana (Medicina Interna 1a, Dipartimento di Scienze Cliniche, e di Comunità, Fondazione, Irccs, Università di Milano), Corazza Gino Roberto, Miceli, Emanuela, Padula Donatella (Clinica Medica, I, Reparto, 11, IRCCS Policlinico San Matteo di Pavia, Pavia), Schinco, Giuseppina, Spreafico Sibilla (UOC Geriatria, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico), Secchi Beatrice (UOC Medicina Interna, Ospedale, Bassini, Milano), Vanoli, Massimo, Casella Gianluca (SC Medicina Interna, Azienda Ospedaliera della Provincia di Lecco, Ospedale di Merate, Lecco), Serra Maria Grazia (UOC Medicina, Panico', Azienda Ospedaliera 'Cardinale G., Lecce), Longo, Stefania, Antonaci Salvatore (UOC Medicina Interna, Azienda Ospedaliera Policlinico, Bari), Belfiore, Anna, Giuseppe Palasciano, Frualdo Mariella (Clinica Medica 'A. Murri'-Direttore Prof., Ventrella, Francesco, Iamele Luigi (Struttura Complessa di Medicina Interna, Cerignola, Asl, Foggia), Bianco Cesare (UOC Medicina Interna, Tropea), Santovito, Donato, Mezzetti, Andrea, Cipollone Francesco (Centro di Eccellenza Europeo, e di Riferimento Regionale per l'Aterosclerosi, l'Ipertensione Arteriosa, e le Dislipidemie, Università, Chieti), Nicolai, Salvatore, Salvati Filippo (UO Medicina Interna, Ospedale di Ortona, ASL 02 Abruzzo), Rini Giovan Battista, Scozzari Francesca (UOC Medicina Interna ed Ipertensione, Dipartimento Biomedico di Medicina Interna e Specialistica (Di. Bi. M. I., S), Giaccone' di Palermo), Policlinico 'P., Muiesan Maria Lorenza, Salvetti, Massimo, Bazza Abramo (Dipartimento di Scienze Cliniche, e Sperimentali, Università di Brescia, 2° Medicina Generale Spedali Civili, Brescia), Picardi, Antonio, De Vincentis Antonio (UOC Medicina Clinica, Policlinico Universitario Campus Bio-Medico, Cosio, Paolo, Terzolo Massimo (Medicina Interna, 1, Dipartimento di Scienze Cliniche, e Biologiche, AOU San Luigi Gonzaga, Università di Torino), Madaffari, Bruno, Parasporo Bruno (UO Medicina Interna, Azienda Ospedaliera Bianchi Melacrino Morelli, Reggio, Calabria), Fenoglio, Luigi, Bracco, Christian, Melchio Remo (SC Medicina Interna, Croce e Carle, AO S., Cuneo), Gentili, Tamira, Salvi Aldo (Medicina Generale, - Settore Subintensivo, Azienda, Ospedaliero-Universitaria, Ancona), Nitti, Cinzia, Falsetti Lorenzo (Medicina Generale, - Settore Ordinario, Gabrielli, Armando, Paglione Ivano (Clinica Medica, Capucci, Alessandro, Brambatti, Michela, Sparagna Armando (Clinica di Cardiologia, Ospedale, Torrette, Tirotta Daniela (UO Medicina Generale IV, Ospedale, Cervesi, Cattolica), Andreozzi, Paola, Ettorre, Evaristo, Cipriani Elisa (Area Geriatria, DAI Medicina Interna, Sapienza-Università di Roma, Rossi Fanelli Fillippo, Delfino Massimo (UOC Medicina Interna, H, Immunologia, Clinica, Nutrizione, Clinica, Endocrinologia, Glorioso, Nicola, Melis, Giada, Marras, Gianfranca, Matta Michela (Ambulatorio Ipertensione Arteriosa, e Patologie Correlate, Aou, Sassari, Sassari), Sacco Andrea (UOC Medicina Interna, PO Madonna delle Grazie, Matera), Stellitano, Elio, Scordo Anna (UO Medicina, PO 'Tiberio Evoli', Melito Porto Salvo), Russo, Franco, Caruso Assunta Antonietta (UOC Medicina Generale di Rogliano, AO di Cosenza), Porreca, Ettore, Santilli, Francesca, Tana Marco (UO Medicina Interna, e Geriatria, Ospedale Clinicizzato Colle Dell'Ara, D'Annunzio, Università G., Chieti-Pescara), Ferri, Claudio, Grassi, Davide, Di Giosia Paolo (Divisione di Medicina Interna Universitaria, - Ospedale San Salvatore, Dipartimento, Mesva, Università, Dell'Aquila, L'Aquila), Portincasa Piero (Clinica Medica 'Murri', Dipartimento di Scienze Mediche, e Oncologia Umana, Università degli Studi di Bari), Muscianisi Giuseppe (ASP Reggio Calabria, Saline Joniche), Giordani, Sara, Stanghellini Vincenzo (Dipartimento di Scienze Mediche, e Chirurgiche, Università degli Studi di Bologna), Sabbà, Carlo, Suppressa Patrizia (UOC Geriatria e Centro di assistenza, e ricerca sovraziendale per le malattie rare, Mancuso, Giuseppe, Bartone, Mosè, Calipari Daniela (UOC Medicina Interna, Presidio, Ospedaliero, ASP di Catanzaro), Arcidiacono, Giuseppe, Bellanuova Ignazio (UOC Cardiologia, e UTIC, Catania), Ferraro, Maria, Scalzo, Antonio, Marigliano Giampietro (ASP Cosenza), Cozzolino, Domenico, Lampitella, Antonio, Acri Vera (Dipartimento di Internistica Clinica, e Sperimentale, Galasso, Domenico, Mazzei, Francesca, Galasso Salvatore (RSA Madonna di Porto Gimigliano, Catanzaro), Buratti Alberto (Azienda Ospedaliera della Provincia di Pavia, UO Medicina Interna, Ospedale, Civile, Casorate, Primo, Porta, Massimo, Brizzi Maria Felice (SC Medicina Interna 1U, Azienda, Ospedaliera, Torino), Fattorini, Annalisa, Sampietro, Francesca, D’Angelo Armando (Coagulation Service and Thrombosis Research Unit, IRCCS Ospedale San Raffaele, Pala, Marco, Fabbian, Fabio, Manfredini Roberto (UOC Clinica Medica, Anna, Azienda Ospedaliera-Universitaria S., Ferrara), Moroni, Carlo, Valente, Lucia, Lopreiato Francesco (Laboratorio di Ecocardiografia-Cardiologia Preventiva, DAI Cuore, e Grossi Vasi, Parente Fernando (UOC Medicina Interna, Granata Massimo (Immunologia Clinica, A, Moia, Marco, Braham Simon (Fondazione IRCCS Ca'Granda, Ospedale Maggiore Policlinico, Rossi, Marco, Pesce Margherita (Dipartimento di Medicina Clinica, e Sperimentale, Università di Pisa), Gentile, Adelina, Catozzo Vania (UO Medicina, Ldp, Loreto, Ferranti, Edoardo, Soldini, Maurizio, Di Napoli Mariarosaria, Baciarello Giacinto (UOC Cardiologia Preventiva, e Riabilitativa, Rancan, Elena, Ageno, Walter, Guasti Luigina (Dipartimento di Medicina Clinica, e Sperimentale, Università, Dell'Insubria, Varese), Ciccaglioni, Antonio, Negri, Silvia, Polselli Marco (Centro Elettro-Stimolazione Cardiaca, Prisco Domenico (SOD Patologia Medica, Aou, Careggi, Firenze), Pignataro Francesca Serena, Pastori, Daniele, Ferro, Domenico, Loffredo, Lorenzo, Cangemi, Roberto, Perri, Ludovica, Polimeni, Licia, Catasca, Elisa, Raparelli, Valeria, Napoleone, Laura, Schillizzi, Marianna, Vicario, Tommasa, Russo, Roberta, Gentile Maria Cristina, Saliola, Mirella, Del Ben Maria, Angelico Francesco (I Clinica Medica, Sapienza-Università di, Roma)., Violi F, Daví G, Hiatt W, Lip GY, Corazza GR, Perticone F, Proietti M, Pignatelli P, Vestri AR, Basili S, ARAPACIS Study Investigators: […, Alessandri C, Serviddio G, Fascetti S, Serra P, Palange P, Greco E, Bruno G, Averna M, Giammanco A, Sposito P, De Cristofaro R, De Gennaro L, Loria P, Pellegrini E, Cominacini L, Mozzini C, Spovieri M, Spagnuolo V, Cerqua G, Cerasola G, Mulé G, Barbagallo M, Lo Sciuto S, Monteverde A, Saitta A, Lo Gullo A, Malatino L, Cilia C, Licata G, Tuttolomondo A, Conigliaro R, Pinto A, Di Raimondo D, Signorelli S, Anzaldi M, De Palma D, Galderisi M, Cudemo G, Galletti F, Fazio V, De Luca N, Meccariello A, Caputo D, De Donato MT, Iannuzi A, Bresciani A, Giunta R, Cimini C, Utili R, Durante M, Emanuele AF, Adinolfi LE, Cristiana S, Restivo L, Bellis P, Tirelli P, Sacerdoti D, Pesce P, Vanni D, Iuliano L, Palazzuoli A, Cacciafesta M, Gueli N, Capeci W, Tarquino N, Pellegrini F, Vincentelli GM, Ravallese F, Santini C, Letizia C, Petramala L, Zinnamosca L, Cilli M, Savoriti C, Falaschi P, Martocchia A, Stefanelli M, Marigliano V, Lo Iacono C, Brusco S, Bertazzoni G, El Halabieh Elias A, Paradiso M, Lizzi EM, Stefano T, Paola B, Cerci S, Ciavolella M, Di Veroli C, Malci F, De Ciocchis A, Abate D, Castellino P, Curto I, Vecchio C, Mannarino E, Pasqualini L, Fattori C, Pende A, Denegri A, Nathan A, Ricchio R, Fimognari FL, Alletto M, Messina S, Sesti G, Arturi F, Gembiale A, Scarpino PE, Carullo G, Pierluigi F, Battaglia G, Vadili G, Atzori S, Delitala G, Davì G, Angelucci E, Simona S, Giancarlo T, De Feudis L, Di Michele D, Fava A, Balsano C, De Ciantis P, Giovambattista D, Camerota A, Migliacci R, Porciello G, Mezzetti M, Gresele P, Vedovati C, Fierro T, Puccetti L, Scarpini F, Bertolotti M, Mussi C, Boddi M, Savino A, Contri S, Saller A, Fabris F, Pesavento R, Filippi L, Vedovetto V, Puato M, Treleani M, Maselli M, Corradin ML, Giantin V, Semplicini A, Minuz P, Calabria S, Romano S, Fantin F, Manica A, Stockner I, Pattis P, Guttman B, Catena C, Colussi GL, Annoni G, Bruni AA, Castagna A, Miceli E, Padula D, Schinco G, Spreafico S, Secchi B, Vanoli M, Casella G, Serra MG, Longo S, Antonaci S, Belfiore A, Frualdo M, Francesco V, Iamele L, Bianco C, Santovito D, Mezzetti A, Cipollone F, Nicolai S, Salvati F, Battista RG, Scozzari F, Muiesan ML, Salvetti M, Bazza A, Picardi A, De Vincentis A, Cosio P, Terzolo M, Fenoglio L, Bracco C, Melchio R, Gentili T, Salvi A, Nitti C, Falsetti L, Gabrielli A, Paglione I, Capucci A, Brambatti M, Sparagna A, Tirotta D, Andreozzi P, Ettorrre E, Cipriani E, Fanelli Fillippo R, Delfino M, Glorioso N, Melis G, Marras G, Matta M, Sacco A, Stellitano E, Scordo A, Russo F, Caruso Assunta A, Porreca E, Santilli F, Tana M, Ferri C, Grassi D, Di Giosia P, Portincasa P, Muscianisi G, Giordani S, Stanghellini V, Sabbà C, Supressa P, Mancuso G, Bartone M, Calipari D, Arcidiacono G, Bellanuova I, Ferraro M, Scalzo A, Marigliano G, Cozzolina D, Lampitella A, Acri V, Galasso D, Mazzei F, Galasso S, Buratti A, Porto M, Brizzi MF, Fattorini A, Sampietro F, D'Angelo A, Pala M, Fabbian F, Manfredini R, Moroni C, Valente L, Lopreiato F, Parente F, Granata M, Moia M, Braham S, Rossi M, Pesce M, Gentile A, Catozzzo V, Ferranti E, Soldini M, Di Napoli M, Baciarello G, Rancan E, Ageno W, Guasti L, Ciccaglioni A, Negri S, Polselli M, Prisco D, Pignataro FS, Pastori D, Ferro D, Loffredo L, Cangemi R, Perri L, Polimeni L, Catasca E, Raparelli V, Napoleone L, Schillizzi M, Vicario T, Russo R, Gentile MC, Saliola M, Del Ben M, Angelico F, Farcomeni A, Di Tanna G, Davi' G, Traisci G, Montebianco Abenavoli L, Grembiale A, Di Minno G, Durante ME, Pattoneri P, Boari B, Fabio G, Perego F, Bianchi Paola I, Angeli A, Colombo BM, Giannelli G, Vidili G, Torres D, Hijazl D, Gatta A, Mannucci Mannuccio P, Licata G., and …]
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Adult ,Male ,Risk ,therapy ,atrial fibrillation ,cardiovascular disease ,peripheral vascular disease ,Aged ,Atrial Fibrillation ,Female ,Humans ,Internal Medicine ,Italy ,Middle Aged ,Peripheral Arterial Disease ,Prevalence ,Registries ,Societies, Medical ,Ankle Brachial Index ,ATRIAL FIBRILLATION ,Cardiology and Cardiovascular Medicine ,Medical ,RISK FACTORS ,cardiovascular diseases ,Societies - Abstract
To the Editor: Nonvalvular atrial fibrillation (NVAF) is the most common sustained arrhythmia encountered in clinical practice and is associated with a 5-fold increased risk for stroke (1). Moreover, patients with NVAF often suffer from atherosclerotic complications such as acute myocardial infarction (AMI) (2). Peripheral artery disease (PAD) is an established marker of systemic atherosclerosis but its prevalence in NVAF is still unclear. We reasoned that inclusion of ankle-brachial index (ABI), which is an established tool for diagnosis of PAD (3), in the CHA2DS2-VASc (4) score would better define the prevalence of vascular disease. To address this issue, the Italian Society of Internal Medicine (SIMI) established an Italian registry documenting ABI in NVAF patients. The Atrial Fibrillation Registry for the ARAPACIS (Ankle-brachial Index Prevalence Assessment: Collaborative Italian Study) study is an independent research project involving all Regional Councils of SIMI. The first objective of the study was to estimate the prevalence of ABI ≤0.90 in NVAF patients. Consecutive patients with NVAF referred to internal medicine wards were eligible for the enrollment. Enrollment started in October 2010 and continued until October 30, 2012. Patients were enrolled if they were 18 years or older and had a diagnosis of NVAF, recording during the qualifying admission/consultation or in the preceding 12 months, and if it was possible to obtain the ABI measurement. Exclusion criteria included the following: acquired or congenital valvular AF, active cancer, disease with life expectancy 0.90 (93% vs. 82%; p < 0.0001). Logistic regression analysis demonstrated that ABI ≤0.90 was significantly associated with a smoking habit (odds ratio [OR]: 1.99; 95% confidence interval [CI]: 1.48 to 2.66; p < 0.0001), diabetes (OR: 1.93; 95% CI: 1.51 to 2.46; p < 0.0001), age class 65 to 74 years (OR: 2.05; 95% CI: 1.40 to 3.07; p < 0.0001), age class ≥75 years (OR: 3.12; 95% CI: 2.16 to 4.61; p < 0.0001), and history of previous transient ischemic attack/stroke (OR: 1.64; 95% CI: 1.20 to 2.24; p = 0.002). Vascular disease, as assessed by the history elements of CHA2DS2VASc score, was recorded in 17.3% of patients; inclusion of ABI ≤0.90 in the definition of vascular disease yielded a total prevalence of 33%. A higher prevalence of vascular disease was detected if ABI ≤0.90 was included in the CHA2DS2VASc score (Fig. 1). CHA2DS2VASc including ABI ≤0.90 was more associated with previous stroke (43%; OR: 1.85; 95% CI: 1.41 to 2.44; p < 0.0001) compared to CHA2DS2VASc with ABI 0.91 to 1.39 (23%; OR: 1.52; 95% CI: 1.10 to 2.11; p = 0.0117). To the best of our knowledge, there is no large-scale study that specifically examined the prevalence of ABI ≤0.90 in NVAF. In our population, 21% had ABI ≤0.90 indicating that NVAF is often associated with systemic atherosclerosis. The CHADS2 has been recently refined with the CHA2DS2-VASc score, which includes vascular disease as documented by a history of AMI, symptomatic PAD, or detection of atherosclerotic plaque in the aortic arch (4). Comparison of vascular prevalence as assessed by CHA2DS2-VASc score and/or ABI ≤0.90 is of interest to define the potentially positive impact of measuring ABI in the management of NVAF patients. Inclusion of ABI ≤0.90 in the definition of vascular disease greatly increased the prevalence of vascular disease, which increased from 17.3% (based on history alone) to 33% (based on ABI) in the entire population. If ABI ≤0.90 was encompassed in the definition of vascular disease of CHA2DS2-VASc score the prevalence of vascular disease increased in every risk class. Inclusion of ABI ≤0.90 in the CHA2DS2-VASc score allowed us to better define the risk profile of NVAF patients with an up-grading of the risk score in each CHA2DS2-VASc score category. This may have important therapeutic implications if the new score could be tested prospectively, as a higher number of NVAF patients would potentially be candidates for an anticoagulant treatment by measuring ABI. A prospective study is, therefore, necessary to validate the risk score of this new definition of vascular disease. In conclusion, this study provides the first evidence that one-fifth of NVAF patients had an ABI ≤0.90, indicating that it may represent a simple and cheap method to better define the prevalence of vascular disease in NVAF.
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- 2013
140. 'Il lavoro'
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TOGNONATO, CLAUDIO ALBERTO, A CURA DI ROBERTO CIPRIANI E GIANNI LOSITO, and Tognonato, CLAUDIO ALBERTO
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- 2008
141. Awareness of everyday effects of climate change: The climate change perceptual awareness scale (CCPAS).
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Cipriani E, Gemignani A, and Menicucci D
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Climate change is intrinsically complex and demands a certain degree of abstraction. However, different individuals report a wide range and degree of tangible and sensory experiences of climate change. As perceptual and sensory awareness of climate change has important consequences for the promotion of sustainable behaviors, pro-climate policies, and clinical interventions for climate-related disorders such as climate anxiety, new specific tools are required: herein we detail the development of a psychometric measure of perceptual awareness of climate change, as well as provide evidence for its discriminant, convergent, and predictive validity for sustainable behaviors. The administration of this scale on a representative sample of the UK population (Study 1) yielded a 4-factor structure, with items measuring perception of temperature changes and those measuring perception of humidity changes loading on separate factors, and two additional factors identifying the awareness of own feelings and perception of media attention on climate change. A second administration (Study 2) to an independent sample gathered from the Italian population supports the reliability of this factorial structure. As the rising field of climate neuroscience starts to investigate the determinants of perceptions of climate change, this novel scale will allow assessing the perceptual features affecting awareness of climate change., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors. Published by Elsevier Ltd.)
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- 2024
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142. [The Signature Biobank: History and perspectives of a longitudinal project investigating the biological, psychological, and social signatures of patients visiting the emergency of the Institut universitaire en santé mentale de Montréal].
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Cipriani E, Kerr P, Le Page C, Giguère CÉ, Lupien S, Guay S, and Juster RP
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- Humans, Quebec, Female, Male, Longitudinal Studies, Adult, Middle Aged, Databases, Factual, Emergency Services, Psychiatric, Young Adult, Adolescent, Aged, Mental Disorders
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Objectives In 2008, the National Institute of Mental Health (NIMH) published its strategic plan to structure future research aims and objectives including the development of a new method of classifying mental health disorders. This strategic plan gave rise to the Research Domain Criteria (RDoC) project, a framework aimed at establishing major functional domains of the human psyche ranging from normal to pathological. The Signature Consortium was created in 2009 to develop a data bank capable of contributing to the development of RDoC by identifying profiles, or Signatures, of a psychiatric population, collecting biological, psychosocial, and clinical indicators at critical moments in the care and follow-up of patients visiting the care structures of the Institut universitaire en santé mentale de Montréal (IUSMM). Here, we will briefly present the available data and outline some socio-demographic characteristics of our sample, in particular according to diagnosis. Methods By involving over 80 researchers, clinicians, staff, and the support of the IUSMM's institutional services (laboratory, IT, legal and ethics departments), this initiative has led to the creation of a unique data bank in Canada. Data for this biobank were collected during patients' visits to the IUSMM's psychiatric emergency department and during a follow-up in outpatient clinics. A control group was also created, with local recruitment of participants with no self-reported history of psychiatric hospitalization in the last 5 years, and with similar demographics to the psychiatric cohort. Psychological data (e.g., depressive, and psychotic symptoms scales) and socio-demographic data (e.g., marital status) were gathered from self-reported questionnaires. Medical and administrative data (e.g., treatment and diagnosis) were collected from treating psychiatrists and from the hospital's electronic registry (OACIS). Blood, hair, and saliva samples were also collected and analyzed to measure numerous biomarkers. Socio-demographic characteristics were compared based on primary diagnosis. Results Between 2012 and 2020, the Signature Biobank recruited 149 control participants and over 2172 psychiatric patients aged 17 to 81, of whom 2085 agreed to complete questionnaires, and 1986 donated biological samples. Thanks to these data, the Biobank has contributed to over forty research projects, 16 scientific publications in indexed international journals, permitted to validate 5 psychosocial questionnaires for psychiatric inpatients, and was used to create a composite sociocultural gender score. Globally, the participants presented a precarious socio-demographic profile. Patients diagnosed with a psychotic disorder seem to present the most disadvantaged profile regarding financial, professional, and relational dimensions. Conclusion The Signature Biobank is a unique biobank in North America studying mental health disorders by collecting bio-psycho-social data and associated biospecimens in psychiatric emergency setting. Although recruitment and data collection are completed, the Biobank continues to add biological data through sample analysis and participation in independent study projects.
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- 2024
143. Insomnia, poor sleep quality and perinatal suicidal risk: A systematic review and meta-analysis.
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Palagini L, Cipriani E, Miniati M, Bramante A, Gemignani A, Geoffroy PA, and Riemann D
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- Humans, Female, Pregnancy, Risk Factors, Pregnancy Complications, Peripartum Period psychology, Depression, Sleep Quality, Sleep Initiation and Maintenance Disorders, Suicidal Ideation
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Suicidal risk in mothers is a public health priority. Risk factors include biological, psychological and psychosocial factors. Among the biological factors, the role of sleep disturbances as potential contributors to increased suicidal risk during the peripartum period is becoming apparent. To explore this further, we conducted a systematic review following the PRISMA criteria. Currently, 10 studies have examined the role of insomnia and poor sleep quality in suicidal risk during the peripartum period and have involved 807,760 women. The data showed that disturbed sleep and poor sleep quality increase the risk of suicidal ideation in both pregnant women with and without perinatal depression. The results of the meta-analysis indicated that insomnia and poor sleep quality increase the odds of suicidal risk in pregnant women by more than threefold (OR = 3.47; 95% CI: 2.63-4.57). Specifically, the odds ratio (OR) for poor sleep quality was 3.72 (95% CI: 2.58-5.34; p < 0.001), and for insomnia symptoms, after taking into account perinatal depression, was 4.76 (95% CI: 1.83-12.34; p < 0.001). These findings emphasise the importance of assessing and addressing sleep disturbances during the peripartum period to mitigate their adverse effects on peripartum psychopathology and suicidal risk., (© 2023 European Sleep Research Society.)
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- 2024
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144. Do Individual Differences in Perception Affect Awareness of Climate Change?
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Cipriani E, Frumento S, Grassini S, Gemignani A, and Menicucci D
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One significant obstacle to gaining a widespread awareness of the ongoing climate change is the nature of its manifestations in relation to our perception: climate change effects are gradual, distributed, and sometimes seemingly contradictory. These features result in a lag in collective climate action and sometimes foster climate skepticism and climate denial. While the literature on climate change perception and belief has thoroughly explored its sociocultural and sociopolitical aspects, research on the potential contribution of psychophysiological factors remains scarce. In this perspective paper, we outline evidence and arguments for the involvement of psychophysiological systems such as thermoception, hygroreception, and interoception in modulating climate change awareness. We discuss psychophysiological mechanisms of climate change awareness in animals and humans, as well as possible sources of individual variance in climate change perception. We conclude by suggesting novel research questions which would be worthwhile to pursue in future studies.
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- 2024
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145. WITHDRAWN: Psychoneuroimmunological characterization in schizophrenia requires health-related adjustments.
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Cipriani E, Kerr P, Page CL, and Juster RP
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- Humans, Psychoneuroimmunology, Antipsychotic Agents therapeutic use, Antipsychotic Agents pharmacology, Schizophrenic Psychology, Schizophrenia immunology
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- 2024
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146. A step-by-step and data-driven guide to index gender in psychiatry.
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Cipriani E, Samson-Daoust E, Giguère CE, Kerr P, Lepage C, and Juster RP
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- Infant, Newborn, Humans, Male, Female, Adult, Gender Identity, Mood Disorders, Anxiety Disorders, Psychotic Disorders, Psychiatry
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Beyond sex as a binary or biological variable, within-sex variations related to sociocultural gender variables are of increasing interest in psychiatric research to better understand individual differences. Using a data-driven approach, we developed a composite gender score based on sociodemographic and psychosocial variables showing sex differences in a sample of psychiatric emergency patients upon admission (N = 1708; 39.4% birth-assigned females; mean age = 40 years; age standard deviation = 14). This gender score was extracted from a confirmatory factor analysis (CFI = 0.966; RMSEA = 0.044, SRMR = 0.030) and could predict a person's birth-assigned sex with 67% accuracy. This score allowed the further identification of differences on impulsivity measures that were absent when looking solely at birth-assigned sex. Female birth-assigned sex was also associated with higher rates of mood and personality disorder diagnoses, while higher feminine gender scores were related to higher proportions of anxiety and mood disorder diagnoses. By contrast, male birth-assigned sex and higher masculine gender scores were associated with higher proportions of psychotic and substance use disorder diagnoses. Patients with undifferentiated gender scores (i.e., scoring between masculine and feminine threshold defined by terciles) were more represented in the psychotic disorder group. Considering both sex and gender in psychiatric research is essential and can be achieved even when using secondary data to index gender comprised of demographic and psychosocial variables., Competing Interests: The authors declare no conflicts of interest., (Copyright: © 2024 Cipriani et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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- 2024
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147. The Hidden Impact of Covid-19 on Memory: Disclosing Subjective Complaints.
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Orrù G, Gemignani A, Cipriani E, Miccoli M, Ciacchini R, Cancemi C, Menicucci D, Montiel CB, Piarulli A, and Conversano C
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Objective: A significant body of research has suggested that the contraction of SARS-CoV-2 may cause memory impairment, even in the months following recovery. In this regard, studies suggest that COVID-19 predominantly targets structures and cortices within the temporal lobe, and the hippocampus, a critical brain structure for memory and spatial navigation.The purpose of this study was to investigate the potential impact of the COVID-19 pandemic on subjective memory complaints, which represent an individual's perception of subtle changes in memory in the absence of an objective memory impairment., Method: to explore how the COVID-19 pandemic may affect subjective memory complaints, we incorporated ad hoc self-reported measures of subjective memory complaints, the "Subjective Memory Complaints Questionnaire" (SMCQ) and the "Prospective and Retrospective Memory Questionnaire" (PRMQ), in our cross-sectional study. Both measures referred to two periods: the pre-pandemic period (T0) and the moment of survey administration (T1) (December 28th, 2021, to February 6th, 2022)., Results: 207 Italian participants accessed the survey, out of which 189 participants were included in the final sample. The majority of the participants were females, and their age ranged from 55 to 65 years. The study revealed a significant increase in the total PRMQ score at T1 compared to T0 (p = 0.02). However, no significant differences were found between PRMQ and SMCQ scores of COVID-19-negative individuals and those who tested positive for COVID-19 in the last 12 months from the date of completing the survey. McNemar's test showed a statistically significant increase in the score of item 1 ("Do you think that you have a memory problem?" (p = 0.016) and item 10 ("Do you lose objects more often than you did previously") (0.019) of the SMCQ, while for the PRMQ, significant increases were found in several individual items., Conclusions: our study suggests that subjective memory complaints increased during the pandemic, potentially due to the compound effects of stress and social isolation, rather than solely due to COVID-19 infection. Although a marginal association between COVID-19 and reported prospective memory issues was detected, further investigation is warranted to understand its persistent effects., Competing Interests: Competing interests: None., (© 2023 Giovanni Fioriti Editore s.r.l.)
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- 2023
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148. Doubts and concerns about COVID-19 uncertainties on imaging data, clinical score, and outcomes.
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Nardi C, Magnini A, Calistri L, Cavigli E, Peired AJ, Rastrelli V, Carlesi E, Zantonelli G, Smorchkova O, Cinci L, Orlandi M, Landini N, Berillo E, Lorini C, Mencarini J, Colao MG, Gori L, Luzzi V, Lazzeri C, Cipriani E, Bonizzoli M, Pieralli F, Nozzoli C, Morettini A, Lavorini F, Bartoloni A, Rossolini GM, Matucci-Cerinic M, Tomassetti S, and Colagrande S
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- Male, Female, Humans, Aged, SARS-CoV-2, Retrospective Studies, Lung diagnostic imaging, Tomography, X-Ray Computed methods, COVID-19 diagnostic imaging
- Abstract
Background: COVID-19 is a pandemic disease affecting predominantly the respiratory apparatus with clinical manifestations ranging from asymptomatic to respiratory failure. Chest CT is a crucial tool in diagnosing and evaluating the severity of pulmonary involvement through dedicated scoring systems. Nonetheless, many questions regarding the relationship of radiologic and clinical features of the disease have emerged in multidisciplinary meetings. The aim of this retrospective study was to explore such relationship throughout an innovative and alternative approach., Materials and Methods: This study included 550 patients (range 25-98 years; 354 males, mean age 66.1; 196 females, mean age 70.9) hospitalized for COVID-19 with available radiological and clinical data between 1 March 2021 and 30 April 2022. Radiological data included CO-RADS, chest CT score, dominant pattern, and typical/atypical findings detected on CT examinations. Clinical data included clinical score and outcome. The relationship between such features was investigated through the development of the main four frequently asked questions summarizing the many issues arisen in multidisciplinary meetings, as follows 1) CO-RADS, chest CT score, clinical score, and outcomes; 2) the involvement of a specific lung lobe and outcomes; 3) dominant pattern/distribution and severity score for the same chest CT score; 4) additional factors and outcomes., Results: 1) If CT was suggestive for COVID, a strong correlation between CT/clinical score and prognosis was found; 2) Middle lobe CT involvement was an unfavorable prognostic criterion; 3) If CT score < 50%, the pattern was not influential, whereas if CT score > 50%, crazy paving as dominant pattern leaded to a 15% increased death rate, stacked up against other patterns, thus almost doubling it; 4) Additional factors usually did not matter, but lymph-nodes and pleural effusion worsened prognosis., Conclusions: This study outlined those radiological features of COVID-19 most relevant towards disease severity and outcome with an innovative approach., (© 2023. The Author(s).)
- Published
- 2023
- Full Text
- View/download PDF
149. Insomnia During the Perinatal Period and its Association with Maternal and Infant Psychopathology: A Systematic Review and Meta-Analysis.
- Author
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Palagini L, Cipriani E, Caruso V, Sharma V, Gemignani A, Bramante A, Miniati M, and Riemann D
- Subjects
- Pregnancy, Infant, Newborn, Female, Infant, Humans, Anxiety complications, Depression complications, Sleep Initiation and Maintenance Disorders etiology
- Abstract
Purpose of Review: While sleep serves important regulatory functions for mental health, sleep disturbances, in particular insomnia, may contribute to mental disorders. Since insomnia symptoms are frequent during the perinatal period, the aim of this work is to systematically review the potential association between perinatal insomnia and maternal and infant psychopathology., Recent Findings: A systematic search was conducted according with PRISMA guidelines, and meta-analytic calculations were conducted. Totally, 34 studies were included and involved 835,021 perinatal women. Four meta-analysis yielded four statistically significant random-effect models. All models show that women with perinatal symptoms of insomnia possess increased odds of developing clinically relevant symptoms of depression OR = 3.69, p = 0.001 and anxiety OR = 2.81; p < 0.001, as well as increased suicidal risk OR = 3.28; p < 0.001, and distress in the newborn OR = 2.80 (P = 0.007). These findings emphasize the role of assessing and addressing insomnia during the perinatal period to mitigate its negative effect on maternal and infant mental health via sleep regulation., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
150. Progression after First-Line Cyclin-Dependent Kinase 4/6 Inhibitor Treatment: Analysis of Molecular Mechanisms and Clinical Data.
- Author
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Villa F, Crippa A, Pelizzoni D, Ardizzoia A, Scartabellati G, Corbetta C, Cipriani E, Lavitrano M, and Ardizzoia A
- Subjects
- Humans, Female, Cyclin-Dependent Kinase 4, Cell Cycle, Protein Kinase Inhibitors pharmacology, Protein Kinase Inhibitors therapeutic use, Cyclin-Dependent Kinase 6, Breast Neoplasms drug therapy, Breast Neoplasms pathology
- Abstract
Cyclin-dependent kinase 4/6 inhibitors (CDK4/6iss) are widely used in first-line metastatic breast cancer. For patients with progression under CDK4/6is, there is currently no standard treatment recommended at the category 1 level in international guidelines. The purpose of this article is to review the cellular mechanisms underlying the resistance to CDK4/6is, as well as treatment strategies and the clinical data about the efficacy of subsequent treatments after CDK4/6is-based therapy. In the first part, this review mainly discusses cell-cycle-specific and cell-cycle-non-specific resistance to CDK4/6is, with a focus on early and late progression. In the second part, this review analyzes potential therapeutic approaches and the available clinical data on them: switching to other CDK4/6is, to another single hormonal therapy, to other target therapies (PI3K, mTOR and AKT) and to chemotherapy.
- Published
- 2023
- Full Text
- View/download PDF
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