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371 results on '"Chou, Janice Y."'

101. Viral Hepatitis, Acute

Author

Balemans, Wendy, primary, Van Hul, Wim, additional, Valko, Marian, additional, Moncol, Jan, additional, Denson, Lee A., additional, Mela, Maria, additional, Thalheimer, Ulrich, additional, Samonakis, Dimitrios, additional, Burroughs, Andrew K., additional, Leung, Alexander K. C., additional, Sauve, Reginald S., additional, Robson, William Lane M., additional, Bornstein, Stefan R., additional, Aunapuu, Marina, additional, Arend, Andres, additional, Recher, Mike, additional, Lang, Karl S., additional, Melms, Arthur, additional, Sunderkötter, Cord, additional, Sindrilaru, Anca, additional, Divizia, Maria Teresa, additional, Lerone, Margherita, additional, Ravazzolo, Roberto, additional, Aggarwal, Vimla S., additional, Arnold, Jelena S., additional, Blonska*, Anna, additional, Morrow, Bernice E., additional, Kubitz, Ralf, additional, Yamaki, Takashi, additional, Connelly, Kim A., additional, Gilbert, Richard E., additional, Ma, Lucia K., additional, Ma, Patrick T. S., additional, Moorjani, Narain, additional, Sugden, Peter H., additional, Depre, Christophe, additional, Selvanayagam, Joseph B., additional, Burow, Annika, additional, Delacrétaz, Etienne, additional, Chen, Zhuang, additional, Shou, Weinian, additional, Stockfleth, Eggert, additional, Nindl, Ingo, additional, Brandt, Thomas, additional, Strupp, Michael, additional, Theil, Diethilde, additional, Andresen, Brage Storstein, additional, Ludwig, Amei, additional, Hengel, Hartmut, additional, Bode, Johannes G., additional, Erhardt, Andreas, additional, Oppido, Guido, additional, Napoleone, Carlo Pace, additional, Gargiulo, Gaetano, additional, Biesalski, Hans K., additional, Gdynia, Hans-Jürgen, additional, Ludolph, Albert C., additional, Bitsch, Roland, additional, Akhilender, Naidu K., additional, Zittermann, Armin, additional, Azzi, Angelo, additional, Negis, Yesim, additional, Markel, Arie, additional, Kfir, Nir, additional, Bayer, Johannes, additional, Beissert, Stefan, additional, Chou, Janice Y., additional, Mansfield, Brian C., additional, Hartmann, Arndt, additional, Dietmaier, Wolfgang, additional, and Ten Cate, Hugo, additional

Published
2009
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113. Glycogen storage disease type Ia in canines: a model for human metabolic and genetic liver disease

Author

Specht, Andrew, Fiske, Laurie, Erger, Kirsten, Cossette, Travis, Verstegen, John, Campbell-Thompson, Martha, Struck, Maggie B., Lee, Young Mok, Chou, Janice Y., Byrne, Barry J., Correia, Catherine E., Mah, Cathryn S., Weinstein, David A., and Conlon, Thomas J.

Subjects
Models, Genetic aspects, Research, Risk factors, Glycogen storage diseases -- Risk factors -- Genetic aspects -- Research, Gene mutation -- Research, Dogs -- Models, Gene mutations -- Research, Glycogenosis -- Risk factors -- Genetic aspects -- Research
Abstract

1. Introduction Glycogen storage disease type Ia (GSDIa; von Gierke disease; MIM 232200) is an inherited metabolic disorder resulting from a deficiency in the enzyme glucose 6-phosphatasea (G6Pase; EC 3.1.3.9). [...], A canine model of Glycogen storage disease type Ia (GSDIa) is described. Affected dogs are homozygous for a previously described M121I mutation resulting in a deficiency of glucose-6-phosphatase-α. Metabolic, clinicopathologic, pathologic, and clinical manifestations of GSDIa observed in this model are described and compared to those observed in humans. The canine model shows more complete recapitulation of the clinical manifestations seen in humans including 'lactic acidosis', larger size, and longer lifespan compared to other animal models. Use of this model in preclinical trials of gene therapy is described and briefly compared to the murine model. Although the canine model offers a number of advantages for evaluating potential therapies for GSDIa, there are also some significant challenges involved in its use. Despite these challenges, the canine model of GSDIa should continue to provide valuable information about the potential for generating curative therapies for GSDIa as well as other genetic hepatic diseases.

Published
2011
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122. Responses of Components of the Hepatic Glucose-6-Phosphatase System to the Glucose Demands of Ehrlich Ascites Tumors in Mice

Author

FOSTER, JAMES D., WIEDEMANN, JAY M., CHOU, JANICE Y., and NORDLIE, ROBERT C.

Subjects
Glucose metabolism -- Abnormalities, Endocrine gland tumors -- Physiological aspects, Blood sugar -- Measurement, Health
Abstract

The presence of tumors places rigorous metabolic demands on the host and the growing tumor poses a stress on the host to maintain normal blood glucose levels. Hepatic glucose-6-phosphatase (G6Pase) [...]

Published
2000

128. Development of hepatocellular adenomas and carcinomas in mice with liver-specific G6Pase-α deficiency

Author

Resaz, Roberta, primary, Vanni, Cristina, additional, Segalerba, Daniela, additional, Sementa, Angela R., additional, Mastracci, Luca, additional, Grillo, Federica, additional, Murgia, Daniele, additional, Bosco, Maria Carla, additional, Chou, Janice Y., additional, Barbieri, Ottavia, additional, Varesio, Luigi, additional, and Eva, Alessandra, additional

Published
2014
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131. Treatment of newborn G6pc mice with bone marrow-derived myelomonocytes induces liver repair

Author

Resaz, Roberta, primary, Emionite, Laura, additional, Vanni, Cristina, additional, Astigiano, Simonetta, additional, Puppo, Maura, additional, Lavieri, Rosa, additional, Segalerba, Daniela, additional, Pezzolo, Annalisa, additional, Bosco, Maria Carla, additional, Oberto, Alessandra, additional, Eva, Carola, additional, Chou, Janice Y., additional, Varesio, Luigi, additional, Barbieri, Ottavia, additional, and Eva, Alessandra, additional

Published
2011
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134. Adeno-Associated Virus-Mediated Correction of a Canine Model of Glycogen Storage Disease Type Ia

Author

Weinstein, David A., primary, Correia, Catherine E., additional, Conlon, Thomas, additional, Specht, Andrew, additional, Verstegen, John, additional, Onclin-Verstegen, Karine, additional, Campbell-Thompson, Martha, additional, Dhaliwal, Gurmeet, additional, Mirian, Layla, additional, Cossette, Holly, additional, Falk, Darin J., additional, Germain, Sean, additional, Clement, Nathalie, additional, Porvasnik, Stacy, additional, Fiske, Laurie, additional, Struck, Maggie, additional, Ramirez, Harvey E., additional, Jordan, Juan, additional, Andrutis, Karl, additional, Chou, Janice Y., additional, Byrne, Barry J., additional, and Mah, Cathryn S., additional

Published
2010
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143. 11β-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis Function

Author

Walker, Elizabeth A., primary, Ahmed, Adeeba, additional, Lavery, Gareth G., additional, Tomlinson, Jeremy W., additional, Kim, So Youn, additional, Cooper, Mark S., additional, Ride, Jonathan P., additional, Hughes, Beverly A., additional, Shackleton, Cedric H.L., additional, McKiernan, Patrick, additional, Elias, Elwyn, additional, Chou, Janice Y., additional, and Stewart, Paul M., additional

Published
2007
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