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3,115 results on '"Chen, Xiao-Dong"'

116. Valley-protected backscattering suppression in silicon photonic graphene

Author

Chen, Xiao-Dong and Dong, Jian-Wen

Subjects
Physics - Optics, Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

In this paper, we study valley degree of freedom in all dielectric silicon photonic graphene. Photonic band gap opening physics under inversion symmetry breaking is revisited by the viewpoint of nonzero valley Chern number. Bulk valley modes with opposite orbital angular momentum are unveiled by inspecting time-varying electric fields. Topological transition is well illustrated through photonic Dirac Hamiltonian. Valley dependent edge states and the associated valley-protected backscattering suppression around Z-shape bend waveguide have been demonstrated., Comment: 12 pages, 4 figures

Published
2016
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137. Impact of reduced gravity on food mixing and emptying in human stomach: A numerical simulation study.

Author

Li, Changyong, Chen, Xiao Dong, Xiao, Jie, Deng, Renpan, and Jin, Yan

Subjects
*STOMACH, *BOLUS (Digestion), *GRAVITY, *WEIGHTLESSNESS, *COMPUTER simulation
Abstract

Gravitational conditions in space diverge significantly from those experienced on Earth, and these alterations may have significant effects on gastric digestion, ultimately affecting the health of astronauts. To understand these effects, the behavior of mixing and emptying in the human stomach under both reduced and normal gravity is investigated numerically. The solver utilized in this study is developed based on the open-source toolbox OpenFOAM. The gastric contents consist of water and a soluble food bolus characterized by a density of 1100 kg m−3, viscosity of 10−5 m2 s−1, and diffusivity of 3.09 × 10−9 m2 s−1. The effects of gravity magnitude, initial food bolus location, and terminal antral contractions (TACs) are studied. The numerical results demonstrate that the food retention rate can be increased by up to ∼20% in the initial 6 min as normal gravity is reduced to zero gravity. The numerical results support that gravity favors the emptying of the food through the pylorus. The distributions of food concentrations and pH are also significantly influenced by the gravity condition. Under zero gravity conditions, food in the distal stomach is quickly emptied due to the strong flow dynamics in the antrum. A delay of approximately 6 min is observed when the food bolus is initially located in the proximal stomach. TACs efficiently enhance the emptying and mixing of the food in the distal stomach, while their effects on the proximal stomach are marginal. [ABSTRACT FROM AUTHOR]

Published
2024
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138. Injectable "Homing‐Like" Bioactive Short‐Fibers for Endometrial Repair and Efficient Live Births.

Author

Cao, Yumeng, Qi, Jia, Wang, Juan, Chen, Liang, Wang, Yuan, Long, Yijing, Li, Boyu, Lai, Junliang, Yao, Yejie, Meng, Yiwen, Yu, Xiaohua, Chen, Xiao‐Dong, Ng, Lai Guan, Li, Xinyu, Lu, Yao, Cheng, Xiaoyue, Cui, Wenguo, and Sun, Yun

Subjects
ENDOMETRIUM, DIPOLE interactions, UMBILICAL veins, EXTRACELLULAR matrix, STROMAL cells, CELL adhesion
Abstract

The prevalence of infertility caused by endometrial defects is steadily increasing, posing a significant challenge to women's reproductive health. In this study, injectable "homing‐like" bioactive decellularized extracellular matrix short‐fibers (DEFs) of porcine skin origin are innovatively designed for endometrial and fertility restoration. The DEFs can effectively bind to endometrial cells through noncovalent dipole interactions and release bioactive growth factors in situ. In vitro, the DEFs effectively attracted endometrial cells through the "homing‐like" effect, enabling cell adhesion, spreading, and proliferation on their surface. Furthermore, the DEFs effectively facilitated the proliferation and angiogenesis of human primary endometrial stromal cells (HESCs) and human umbilical vein endothelial cells (HUVECs), and inhibited fibrosis of pretreated HESCs. In vivo, the DEFs significantly accelerated endometrial restoration, angiogenesis, and receptivity. Notably, the deposition of endometrial collagen decreased from 41.19 ± 2.16% to 14.15 ± 1.70% with DEFs treatment. Most importantly, in endometrium‐injured rats, the use of DEFs increased the live birth rate from 30% to an impressive 90%, and the number and development of live births close to normal rats. The injectable "homing‐like" bioactive DEFs system can achieve efficient live births and intrauterine injection of DEFs provides a new promising clinical strategy for endometrial factor infertility. [ABSTRACT FROM AUTHOR]

Published
2024
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139. Primary Small Cell Carcinoma in Nasal Cavity and Paranasal Sinuses: 15 Cases From a Single Center.

Author

Wang, Jian, Fan, Yingying, Chen, Xiao-dong, Xue, Tao, and Chen, Fu-quan

Subjects
NASAL cavity, RADIOTHERAPY, RESEARCH funding, PARANASAL sinuses, DISEASE management, TREATMENT effectiveness, RETROSPECTIVE studies, DESCRIPTIVE statistics, SMALL cell carcinoma, CASE studies, EARLY diagnosis, SURVIVAL analysis (Biometry), EVALUATION
Abstract

Small cell carcinoma (SCC) in the nasal cavity and sinuses is extremely rare. The clinical data of 15 patients with primary SCC in nasal cavity and sinuses were analyzed retrospectively. All patients were treated with surgery, radiotherapy, and chemotherapy. Of the 15 patients, 2 patients are alive for more than 6 years, and 5 patients died after the median follow-up period (11 months). Most of our patients represent the later stage (73% presented at stage III or IV) and had surgery combined with radiotherapy and chemotherapy; however, nearly half of patients have tumor recurrence and/or distant metastasis. SCC of nasal cavity and sinuses often invades surrounding tissues, and the long-term curative rate is generally low. Early diagnosis and comprehensive treatment are key to improve survival. Although the overall survival time of SCC is not optimistic, it is still recommended that patients take comprehensive treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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