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457 results on '"Chen, Huatao"'

102. The global sliding mode tracking control for a class of variable order fractional differential systems

Author

Universidad Politécnica de Cartagena, Universidad de Tecnología de China, Ministerio de Ciencia, Innovación y Universidades, Jiang, Jingfei, Chen, Huatao, Cao, Dengqing, García Guirao, Juan Luis, Universidad Politécnica de Cartagena, Universidad de Tecnología de China, Ministerio de Ciencia, Innovación y Universidades, Jiang, Jingfei, Chen, Huatao, Cao, Dengqing, and García Guirao, Juan Luis

Abstract

In this paper, a novel variable order fractional control approach is proposed for tracking control of both of variable order fractional and constant order fractional order system with uncertain and external disturbance terms. In term of the global sliding mode control theory and terminal sliding mode control method, the system states are guaranteed to stay on the switching surface from the initial time, and then converge to the origin by the designed controllers which are continuous input signals. Such controllers avoid the undesirable chattering and remove the effects of uncertain and external disturbance completely. Finally, the comparison between the variable order fraction controller and the constant order fractional controller is given by numerical simulation, furthermore, numerical results on the effects of the tracking control are provided.

Published
2021

104. Bmal1 promotes prostaglandin E2 synthesis by upregulating Ptgs2 transcription in response to increasing estradiol levels in day 4 pregnant mice

Author

Zhao, Lijia, primary, Yang, Luda, additional, Zhang, Jing, additional, Xiao, Yaoyao, additional, Wu, Meina, additional, Ma, Tiantian, additional, Wang, Xiaoyu, additional, Zhang, Linlin, additional, Jiang, Haizhen, additional, Chao, Hsu-Wen, additional, Wang, Aihua, additional, Jin, Yaping, additional, and Chen, Huatao, additional

Published
2021
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106. Comparative selective signature analysis and high-resolution GWAS reveal a new candidate gene controlling seed weight in soybean

Author

Li Song, Zhang Hongmei, Songsong Li, Liu Xiaoqing, Wei Zhang, Cui Xiaoyan, Chen Huatao, Chen Xin, Yuelin Zhu, and Wenjing Xu

Subjects
0106 biological sciences, Germplasm, Candidate gene, Genetic Linkage, Quantitative Trait Loci, Population genetics, Single-nucleotide polymorphism, Genome-wide association study, Biology, Quantitative trait locus, 01 natural sciences, Polymorphism, Single Nucleotide, Chromosomes, Plant, Gene Expression Regulation, Plant, Genetics, Cultivar, Domestication, Plant Proteins, food and beverages, Chromosome Mapping, General Medicine, Plant Breeding, Genetics, Population, Seeds, Soybeans, Agronomy and Crop Science, Genome, Plant, 010606 plant biology & botany, Biotechnology, Genome-Wide Association Study
Abstract

We detected a QTL qHSW-16 undergone strong selection associated with seed weight and identified a novel candidate gene controlling seed weight candidate gene for this major QTL by qRT-PCT. Soybean [Glycine max (L.) Merr.] provides more than half of the world’s oilseed production. To expand its germplasm resources useful for breeding increased yield and oil quality cultivars, it is necessary to resolve the diversity and evolutionary history of this crop. In this work, we resequenced 283 soybean accessions from China and obtained a large number of high-quality SNPs for investigation of the population genetics that underpin variation in seed weight and other agronomic traits. Selective signature analysis detected 78 (~ 25.0 Mb) and 39 (~ 22.60 Mb) novel putative selective signals that were selected during soybean domestication and improvement, respectively. Genome-wide association study (GWAS) identified five loci associated with seed weight. Among these QTLs, qHSW-16, overlapped with the improvement-selective region on chromosome 16, suggesting that this QTL may be underwent strong selection during soybean improvement. Of the 18 candidate genes in qHSW-16, only SoyZH13_16G122400 showed higher expression levels in a large seed variety compared to a small seed variety during seed development. These results identify SoyZH13_16G122400 as a novel candidate gene controlling seed weight and provide foundational insights into the molecular targets for breeding improvement of seed weight and potential seed yield in soybean.

Published
2020

107. Advances in salinity tolerance of soybean: Genetic diversity, heredity, and gene identification contribute to improving salinity tolerance

Author

Chen Huatao, Liu Xiaoqing, Zhang Hongmei, Chen Xin, Yuan Xingxing, He-ping Gu, and Cui Xiaoyan

Subjects
0106 biological sciences, 0301 basic medicine, Germplasm, heredity, Agriculture (General), Genome-wide association study, Plant Science, Biology, Quantitative trait locus, 01 natural sciences, Biochemistry, S1-972, 03 medical and health sciences, Food Animals, salinity improvement, Genetic variation, soybean, gene identification, Molecular breeding, Genetic diversity, Ecology, business.industry, fungi, food and beverages, Heritability, Biotechnology, Salinity, 030104 developmental biology, genetic variation, Animal Science and Zoology, business, Agronomy and Crop Science, 010606 plant biology & botany, Food Science
Abstract

Salt stress is one of the major abiotic stresses affecting soybean growth. Genetic improvement for salt tolerance is an effective way to protect soybean yield under salt stress conditions. Successful improvement of salt tolerance in soybean relies on identifying genetic variation that confers tolerance in soybean germplasm and subsequently incorporating these genetic resources into cultivars. In this review, we summarize the progress in genetic diversity and genetics of salt tolerance in soybean, which includes identifying genetic diversity for salt tolerant germplasm; mapping QTLs conferring salt tolerance; map-based cloning; and conducting genome-wide association study (GWAS) analysis in soybean. Future research avenues are also discussed, including high throughput phenotyping technology, the CRISPR/Cas9 Genome-Editing System, and genomic selection technology for molecular breeding of salt tolerance.

Published
2018
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108. Circadian clock gene BMAL1 controls testosterone production by regulating steroidogenesis‐related gene transcription in goat Leydig cells

Author

Xiao, Yaoyao, primary, Zhao, Lijia, additional, Li, Weidong, additional, Wang, Xiaoyu, additional, Ma, Tiantian, additional, Yang, Luda, additional, Gao, Lei, additional, Li, Cuimei, additional, Zhang, Manhui, additional, Yang, Dan, additional, Zhang, Jing, additional, Jiang, Haizhen, additional, Zhao, Hongcong, additional, Wang, Yiqun, additional, Chao, Hsu‐Wen, additional, Wang, Aihua, additional, Jin, Yaping, additional, and Chen, Huatao, additional

Published
2021
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109. Integrated Proteomic and Transcriptomic Analyses Reveal the Roles of Brucella Homolog of BAX Inhibitor 1 in Cell Division and Membrane Homeostasis of Brucella suis S2

Author

Zhang, Guangdong, primary, Zhong, Fangli, additional, Chen, Lei, additional, Qin, Peipei, additional, Li, Junmei, additional, Zhi, Feijie, additional, Tian, Lulu, additional, Zhou, Dong, additional, Lin, Pengfei, additional, Chen, Huatao, additional, Tang, Keqiong, additional, Liu, Wei, additional, Jin, Yaping, additional, and Wang, Aihua, additional

Published
2021
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110. The endoplasmic reticulum stress-mediated unfolded protein response protects against infection of goat endometrial epithelial cells by Trueperella pyogenesvia autophagy

Author

Qi, Maozhen, Jiang, Qingran, Yang, Siwei, Zhang, Chenxi, Liu, Jianguo, Liu, Wei, Lin, Pengfei, Chen, Huatao, Zhou, Dong, Tang, Keqiong, Wang, Aihua, and Jin, Yaping

Abstract

ABSTRACTTrueperella pyogenesis an important bacterial pathogen of a wide range of domestic and wild animals. Autophagy plays a key role in eliminating T. pyogenesin a process that is dependent on mechanistic target of rapamycin (mTOR). The endoplasmic reticulum (ER) stress response also is critical for autophagy regulation. However, the relationship between ER stress and T. pyogenesis uncharacterized and the intracellular survival mechanisms of T. pyogeneshave not been investigated adequately. In this study, we show that T. pyogenesinvades goat endometrial epithelial cells (gEECs). Meanwhile, we observed that GRP78 was upregulated significantly, and that unfolded protein response (UPR) also were activated after infection. Additionally, treatment with activators and inhibitors of ER stress downregulated and upregulated, respectively, intracellular survival of T. pyogenes. Blocking the three arms of the UPR pathway separately enhanced T. pyogenessurvival and inflammatory reaction to different levels. We also show that LC3-labeled autophagosomes formed around the invading T. pyogenesand that autolysosome-like vesicles were visible in gEECs using transmission electron microscopy. Moreover, tunicamycin did not inhibit the intracellular survival of T. pyogenesunder conditions in which autophagy was blocked. Finally, severe challenge with T. pyogenesinduced host cell apoptosis which also may indicate a role for ER stress in the infection response. In summary, we demonstrate here that ER stress and UPR are novel modulators of autophagy that inhibit T. pyogenesintracellular survival in gEECs, which has the potential to be developed as an effective therapeutic target in T. pyogenesinfectious disease.

Published
2022
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116. Zearalenone perturbs the circadian clock and inhibits testosterone synthesis in mouse Leydig cells

Author

Zhao, Lijia, primary, Xiao, Yaoyao, additional, Li, Cuimei, additional, Zhang, Jing, additional, Zhang, Yaojia, additional, Wu, Meina, additional, Ma, Tiantian, additional, Yang, Luda, additional, Wang, Xiaoyu, additional, Jiang, Haizhen, additional, Li, Qian, additional, Zhao, Hongcong, additional, Wang, Yiqun, additional, Wang, Aihua, additional, Jin, Yaping, additional, and Chen, Huatao, additional

Published
2020
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123. Adverse effects of circadian desynchrony on the male reproductive system: an epidemiological and experimental study

Author

Liu, Kun, primary, Hou, Guizhong, additional, Wang, Xiaogang, additional, Chen, Huatao, additional, Shi, Fuquan, additional, Liu, Chang, additional, Zhang, Xi, additional, Han, Fei, additional, Yang, Huan, additional, Zhou, Niya, additional, Ao, Lin, additional, Liu, Jinyi, additional, Cao, Jia, additional, and Chen, Qing, additional

Published
2020
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125. STABILITY ANALYSIS OF A SEIQRS EPIDEMIC MODEL ON THE FINITE SCALE-FREE NETWORK.

Author

LIU, XIA, ZHAO, KUN, WANG, JUNLI, and CHEN, HUATAO

Subjects
BASIC reproduction number, INFECTIOUS disease transmission, FINITE, The, EPIDEMICS, COMMUNICABLE diseases, LYAPUNOV functions
Abstract

Taking into account the quarantine for an infectious disease, a susceptible-exposed-infected-quarantined-recovery-susceptible (SEIQRS) epidemic model with time delay on the finite scale-free network is given. The basic reproduction number R 0 , which is dependent not only on all kinds of transfer rates, but also on the topology of the network, is derived. By constructing the Lyapunov function, it is asserted that the disease-free equilibrium of system is locally asymptotically stable if R 0 < 1 , moreover, disease-free equilibrium of system is globally asymptotically stable when R 0 < 1. In addition, the influence of network nodes on the spread of diseases is discussed. Finally, the theoretical results are verified by corresponding numerical simulation. [ABSTRACT FROM AUTHOR]

Published
2022
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126. Analytical predictor–corrector entry guidance for hypersonic gliding vehicles.

Author

Chen, Huatao, Zhao, Kun, Guirao, Juan L.G., and Cao, Dengqing

Subjects
*AERODYNAMIC load, *NUMERICAL integration, *GLIDING & soaring, *BANKING laws, *HYPERSONIC planes, *ALGORITHMS, *QUASI-equilibrium, *TRAJECTORY optimization
Abstract

For the entry guidance problem of hypersonic gliding vehicles (HGVs), an analytical predictor–corrector guidance method based on feedback control of bank angle is proposed. First, the relative functions between the velocity, bank angle and range-to-go are deduced, and then, the analytical relation is introduced into the predictor–corrector algorithm, which is used to replace the traditional method to predict the range-to-go via numerical integration. To eliminate the phugoid trajectory oscillation, a method for adding the aerodynamic load feedback into the control loop of the bank angle is proposed. According to the quasi-equilibrium gliding condition, the function of the quasi-equilibrium glide load along with the velocity variation is derived. For each guidance period, the deviation between the real-time load and the quasi-equilibrium gliding load is revised to obtain a smooth reentry trajectory. The simulation results indicate that the guidance algorithm can adapt to the mission requirements of different downranges, and it also has the ability to guide the vehicle to carry out a large range of lateral maneuvers. The feedback control law of the bank angle effectively eliminates the phugoid trajectory oscillation and guides the vehicle to complete a smooth reentry flight. The Monte Carlo test indicated that the guidance precision and robustness are good. [ABSTRACT FROM AUTHOR]

Published
2021
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131. Social Jetlag and Damage to Male Reproductive System: Epidemiological Observation in European and Chinese Populations and Biochemical Analyses in Mice

Author

Liu, Kun, primary, Hou, Guizhong, additional, Wang, Xiaogang, additional, Chen, Huatao, additional, Shi, Fuquan, additional, Liu, Chang, additional, Zhang, Xi, additional, Han, Fei, additional, Yang, Huan, additional, Zhou, Niya, additional, Ao, Lin, additional, Liu, Jinyi, additional, Cao, Jia, additional, and Chen, Qing, additional

Published
2019
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132. Whole-genome identification and expression analysis of K+ efflux antiporter (KEA) and Na+/H+ antiporter (NHX) families under abiotic stress in soybean

Author

Yuan Xingxing, Chen Xin, Chen Huatao, Bing-yue Wu, Cui Xiaoyan, Liu Xiaoqing, and Zhang Hongmei

Subjects
abiotic stress, Agriculture (General), Antiporter, GmNHXs, Plant Science, Biology, Biochemistry, S1-972, Food Animals, Botany, Gene family, GmKEAs, soybean, Gene, Ecology, Abiotic stress, fungi, food and beverages, Fusion protein, Cytosol, Transmembrane domain, expression pattern, Animal Science and Zoology, Efflux, Agronomy and Crop Science, Food Science
Abstract

Sodium toxicity and potassium insufficient are important factors affecting the growth and development of soybean in saline soil. As the capacity of plants to maintain a high cytosolic, K + /Na + ratio is the key determinant of tolerance under salt stress. The aims of the present study were to identify and analyse expression patterns of the soybean K+ efflux antiporter (KEA) gene and Na + /H + antiporter (NHX) gene family, and to explore their roles under abiotic stress. As a result, 12 soybean GmKEAs genes and 10 soybean GmNHXs genes were identified and analyzed from soybean genome. Interestingly, the novel soybean KEA gene Glyma16g32821 which encodes 11 transmembrane domains were extremely up-regulated and remained high level until 48 h in root after the excessive potassium treatment and lack of potassium treatment, respectively. The novel soybean NHX gene Glyma09g02130 which encodes 10 transmembrane domains were extremely up-regulated and remained high level until 48 h in root with NaCl stress. Imaging of subcellular locations of the two new Glyma16g32821-GFP and Glyma09g02130-GFP fusion proteins indicated all plasma membrane localizations of the two novel soybean genes. The 3D structures indicated that the two soybean novel proteins Glyma09g02130 (NHX) and Glyma16g32821 (KEA) all belong to the cation/hydrogen antiporter family.

Published
2015
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134. Zearalenone perturbs the circadian clock and inhibits testosterone synthesis in mouse Leydig cells.

Author

Zhao, Lijia, Xiao, Yaoyao, Li, Cuimei, Zhang, Jing, Zhang, Yaojia, Wu, Meina, Ma, Tiantian, Yang, Luda, Wang, Xiaoyu, Jiang, Haizhen, Li, Qian, Zhao, Hongcong, Wang, Yiqun, Wang, Aihua, Jin, Yaping, and Chen, Huatao

Subjects
LEYDIG cells, CLOCK genes, TESTOSTERONE, ZEARALENONE, REPORTER genes, SUPRACHIASMATIC nucleus, MYCOTOXINS
Abstract

Zearalenone (ZEA), a mycotoxin, is known to impair reproductive capability by disrupting the synthesis and secretion of testosterone by Leydig cells (LCs), although the mechanism is unknown. Robust rhythmicity of circadian clock and steroidogenic genes were identified in LCs. The aim of this study was to examine whether ZEA significantly attenuated the transcription of core clock genes (Bmal1, Dbp, Per2, and Nr1d1) as well as steroidogenic genes (StAR, Hsd3b2, and Cyp11a1) in mouse testis Leydig cell line (TM3). Western blotting confirmed declines in BMAL1, NR1D1, and StAR protein levels. ZEA also suppressed secreted testosterone levels. In primary LCs, isolated from PER2::LUCIFERASE reporter gene knock in mice, ZEA diminished the amplitude of PER2::LUC expression, and induced a phase shift and period extension. In primary LCs, ZEA also suppressed the expression levels of core clock and steroidogenic genes, reduced protein levels of BMAL1, and decreased testosterone secretion. In vivo expression of core clock and steroidogenic genes were reduced in testes of mice exposed to ZEA for 1 week leading to decreased serum testosterone levels. In summary, data suggest that ZEA may impair testosterone synthesis through attenuation of the circadian clock in LCs culminating in reproductive dysfunction in male mammals. [ABSTRACT FROM AUTHOR]

Published
2021
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136. GmHKT1;4, a novel soybean gene regulating Na+/K+ ratio in roots enhances salt tolerance in transgenic plants

Author

Cui Xiaoyan, Zhang Hongmei, Gu Heping, Chen Huatao, Bingyue Wu, Chen Xin, and Yuan Xingxing

Subjects
Physiology, Transgene, medicine.medical_treatment, fungi, food and beverages, Plant physiology, Plant Science, Genetically modified crops, Biology, Alkali soil, Biochemistry, Downregulation and upregulation, Botany, medicine, Gene family, Agronomy and Crop Science, Saline, Gene
Abstract

Salt is an important factor affecting the growth and development of soybean in saline or alkaline soil. The aims of the present study were to identify and functionally analyse the soybean GmHKTs gene family, and to explore their roles under NaHCO3 and NaCl stresses. The GmHKTs gene family were isolated from soybean using genome sequence information. The GmHKTs gene family were further analysed for the structure and phylogenetic relationship. The expression patterns of soybean GmHKTs genes under NaHCO3 and NaCl stresses were analysed via quantitative real-time PCR. As a result, the expression level of GmHKT1;4 was extremely up regulated in root under each treatment. Overexpression of GmHKT1;4 significantly enhanced the tolerance of transgenic tobacco plants to NaHCO3 and NaCl stresses, compared with null plants. The overexpressed transgenic plants of this gene accomulated more K+ and less Na+ under salt stress, compaired with null plants. Our findings suggest that GmHKT1;4 plays an important role for regulation Na+/K+ ratio in roots under alkaline (NaHCO3) and saline (NaCl) stresses.

Published
2014
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137. High dynamic carrier tracking technology based on Kalman filter

Author

Wu Wenyu Wu Wenyu, Chen Huatao Chen Huatao, Zhuang Ting Zhuang Ting, and Cui Wei

Subjects
Phase-locked loop, Engineering, Frequency-locked loop, Control theory, Filter (video), business.industry, Electronic engineering, Tracking loop, Kalman filter, Tracking (particle physics), business, Stability (probability), Infinite impulse response
Abstract

This paper proposes a carrier tracking method based on the Kalman Filter (KF) for the high dynamic target tracking. In the proposed method, the carrier tracking is achieved via the phase locked loop (PLL) serially assisted by the frequency locked loop (FLL). Furthermore, based on the KF theory, we analyse the carrier tracking loop and get the system equation of PLL and FLL. The proposed method can overcome high dynamic effects and achieve high accuracy tracking with good stability in low carrierto-noise ratio (CNR) circumstance. Compared to the traditional Infinite Impulse Response (IIR) filter tracking method, the proposed method has better tracking performance. Simulation results verify the effectiveness of the proposed method.

Published
2015
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140. A major natural genetic variation associated with root system architecture and plasticity improves waterlogging tolerance and yield in soybean

Author

Ye, Heng, primary, Song, Li, additional, Chen, Huatao, additional, Valliyodan, Babu, additional, Cheng, Peng, additional, Ali, Liakat, additional, Vuong, Tri, additional, Wu, Chengjun, additional, Orlowski, John, additional, Buckley, Blair, additional, Chen, Pengyin, additional, Shannon, J. Grover, additional, and Nguyen, Henry T., additional

Published
2018
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143. Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway

Author

20432578, 50711818, 30467427, Chao, Hsu-Wen, Doi, Masao, Fustin, Jean-Michel, Chen, Huatao, Murase, Kimihiko, Maeda, Yuki, Hayashi, Hida, Tanaka, Rina, Sugawa, Maho, Mizukuchi, Naoki, Yamaguchi, Yoshiaki, Yasunaga, Jun-ichirou, Matsuoka, Masao, Sakai, Mashito, Matsumoto, Michihiro, Hamada, Shinshichi, Okamura, Hitoshi, 20432578, 50711818, 30467427, Chao, Hsu-Wen, Doi, Masao, Fustin, Jean-Michel, Chen, Huatao, Murase, Kimihiko, Maeda, Yuki, Hayashi, Hida, Tanaka, Rina, Sugawa, Maho, Mizukuchi, Naoki, Yamaguchi, Yoshiaki, Yasunaga, Jun-ichirou, Matsuoka, Masao, Sakai, Mashito, Matsumoto, Michihiro, Hamada, Shinshichi, and Okamura, Hitoshi

Abstract

Liver metabolism undergoes robust circadian oscillations in gene expression and enzymatic activity essential for liver homeostasis, but whether the circadian clock controls homeostatic self-renewal of hepatocytes is unknown. Here we show that hepatocyte polyploidization is markedly accelerated around the central vein, the site of permanent cell self-renewal, in mice deficient in circadian Period genes. In these mice, a massive accumulation of hyperpolyploid mononuclear and binuclear hepatocytes occurs due to impaired mitogen-activated protein kinase phosphatase 1 (Mkp1)-mediated circadian modulation of the extracellular signal-regulated kinase (Erk1/2) activity. Time-lapse imaging of hepatocytes suggests that the reduced activity of Erk1/2 in the midbody during cytokinesis results in abscission failure, leading to polyploidization. Manipulation of Mkp1 phosphatase activity is sufficient to change the ploidy level of hepatocytes. These data provide clear evidence that the Period genes not only orchestrate dynamic changes in metabolic activity, but also regulate homeostatic self-renewal of hepatocytes through Mkp1-Erk1/2 signaling pathway.

Published
2017

144. Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway

Author

Chao, Hsu-Wen, primary, Doi, Masao, additional, Fustin, Jean-Michel, additional, Chen, Huatao, additional, Murase, Kimihiko, additional, Maeda, Yuki, additional, Hayashi, Hida, additional, Tanaka, Rina, additional, Sugawa, Maho, additional, Mizukuchi, Naoki, additional, Yamaguchi, Yoshiaki, additional, Yasunaga, Jun-ichirou, additional, Matsuoka, Masao, additional, Sakai, Mashito, additional, Matsumoto, Michihiro, additional, Hamada, Shinshichi, additional, and Okamura, Hitoshi, additional

Published
2017
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150. Genome-wide association study of appearance quality traits and development of KASP makers in vegetable soybean

Author

Yang, Shuo, Jia, Qianru, Wang, Qiong, Wang, Junyan, Li, Jiahao, Hu, Shengyan, Zhang, Wei, Zhang, Hongmei, Guo, Ya, Chen, Xin, Zhu, Yuelin, and Chen, Huatao

Abstract

Vegetable soybean [(Glycine max(L.) Merr.], commonly referred to as edamame, holds significant agricultural importance in China as a legume vegetable harvested at the pod-filling stage (R6). The visual appeal of vegetable soybeans, crucial for consumer preference and marketability, depends on factors such as pod length, pod width, and pod color. This study cultivated 264 vegetable soybeans in Nanjing, Huai'an, and Nantong to assess pod traits using PlantPhenoM, a system for pod phenotypic identification and analysis. Results revealed a variability range of 8.64 to 30.00% in appearance quality traits among vegetable soybeans. Leveraging phenotypic data and employing a genome-wide association study (GWAS) we identified 525 SNPs significantly linked to appearance quality traits in different regions. In addition, candidate genes (Glyma.04G004700, Glyma.15G051600, Glyma.18G225700, Glyma.18G225900, and Glyma.18G272300) associated with target traits were identified, and KASP markers for S04_372771 (pod length), S18_51477324 (pod width), and S18_55553200 (pod color) were developed, respectively. This research offers valuable insights for breeding superior vegetable soybean varieties and lays the groundwork for exploring candidate genes and molecular markers related to appearance and quality traits in vegetable soybeans.

Published
2024
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