2,705 results on '"Charles Todd"'
Search Results
102. A Guid Soldier
- Author
-
Charles Todd and Charles Todd
- Subjects
- Soldiers--Fiction
- Abstract
Set during Inspector Rutledge's time in the Great War, Charles Todd's short story introduces a born killer.It's World War I, and young Glaswegian Dougal Kerr is a new recruit in the British army. Dougal has no family and no past, but his easygoing demeanor belies his cheerless upbringing. There's only one thing that gives Ian Rutledge pause: Dougal is very good at killing, and he doesn't seem to mind it at all--in fact, he seems to relish it. In wartime, how does one tell the difference between a remorseless killer and'a guid soldier'?'A Guid Soldier'by Charles Todd is one of 20 short stories within Mulholland Books's Strand Originals series, featuring thrilling stories by the biggest names in mystery from the Strand Magazine archives. View the full series list at mulhollandbooks.com and listen to them all!
- Published
- 2016
103. Romiplostim as a Viable and Long-term Remedy for Refractory Immune Thrombocytopenia and Concomitant Small B-Cell Lymphoma
- Author
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Jeremy Pantin, Charles Todd Bruker, Paul M. Dainer, Nathan Ryan, and Germame Ajebo
- Subjects
Romiplostim ,Refractory ,business.industry ,Concomitant ,Immunology ,Medicine ,business ,B-cell lymphoma ,medicine.disease ,Immune thrombocytopenia ,medicine.drug - Published
- 2019
104. Beach Bodies
- Author
-
Stasio, Marilyn
- Subjects
Racing the Devil (Novel) -- Book reviews -- Charles, Todd ,Walk Away (Novel) -- Hawken, Sam ,Snowblind (Novel) -- Jónasson, Ragnar -- Book reviews ,Rush of Blood (Billingham, Mark) (Novel) -- Book reviews -- Billingham, Mark ,Books -- Book reviews ,Literature/writing - Abstract
Ugly Americans on a European vacation are always good for a laugh. But you laugh at your peril at the Ugly Brits vacationing in America in RUSH OF BLOOD (Atlantic [...]
- Published
- 2017
105. Detection of oseltamivir‐resistant zoonotic and animal influenza A viruses using the rapid influenza antiviral resistance test
- Author
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Hodges, Erin N., primary, Mishin, Vasiliy P., additional, De la Cruz, Juan, additional, Guo, Zhu, additional, Nguyen, Ha T., additional, Fallows, Eric, additional, Stevens, James, additional, Wentworth, David E., additional, Davis, Charles Todd, additional, and Gubareva, Larisa V., additional
- Published
- 2019
- Full Text
- View/download PDF
106. The Pretty Little Box
- Author
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Charles Todd and Charles Todd
- Subjects
- Books--Fiction
- Abstract
At first glance, the miniature book of hours with gilt-edged pages and the beautiful box that contains it look too small to be of any real consequence – which is exactly why the woman, hardly a thief in her day-to-day life, doesn't think twice about pocketing the package when it catches her eye at the local antiquarian bookshop. But this minor transgression sets in motion a series of events, each one more disastrous than the one before it; as the pretty little box changes hands – being misplaced, stolen, lost, and discarded – it leaves a path of death and destruction in its wake. Meanwhile, all along, one question courses through this chilling history: is the book really the source of its dreadful power, or are the would-be owners of the item already cursed by their covetous desire to possess it – each impelled by one of the seven deadly sins.
- Published
- 2018
107. FAITH ENTERS THE PUBLIC SQUARE: SECULARISM AND FREEDOM OF CONSCIENCE
- Author
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O'Brien, Dennis
- Subjects
Secularism and Freedom of Conscience (Nonfiction work) -- Maclure, Jocelyn -- Taylor, Charles -- Todd, Jane Marie -- Book reviews ,Books -- Book reviews ,Philosophy and religion - Abstract
By Jocelyn Maclure And Charles Taylor Trans. by Jane Marie Todd Harvard Univ. Press 160p $24.95 Secularism and Freedom of Conscience is a small book with a large thesis, an [...]
- Published
- 2012
108. Charles Todd.
- Published
- 1861
109. Charles Todd.
- Published
- 1861
110. Charles Todd.
- Published
- 1860
111. Charles Todd.
- Published
- 1859
112. Charles Todd.
- Published
- 1859
113. Charles Todd.
- Published
- 1859
114. Charles Todd.
- Published
- 1857
115. Association of breast cancer and immune thrombocytopenic purpura
- Author
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Ustun, Celalettin, Dainer, Paul, Hendricks, Linda, Bruker, Charles Todd, and Burgess, Russell
- Subjects
Breast cancer -- Research -- Complications and side effects ,Thrombocytopenic purpura -- Research -- Complications and side effects ,Health ,American Society of Hematology -- Research - Abstract
ABSTRACT: Immune thrombocytopenic purpura (ITP) and breast cancer are common disorders. Only six cases in which patients have had both diseases have been reported. We describe a 40-year-old woman who [...]
- Published
- 2002
116. Aboriginal Interactions with the Overland Telegraph Line, 1870–1880.
- Author
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Jones, Philip
- Subjects
TELEGRAPH & telegraphy ,INDIGENOUS peoples ,SOCIAL interaction ,TELEGRAM services (Novelty) ,DATA transmission systems - Abstract
Aboriginal interactions with the Overland Telegraph Line, along its 3000 kilometres, were never uniform. The Line passed through at least twenty Aboriginal territories; when construction commenced, fewer than half of those groups had met Europeans. Aboriginal people in the northern and southern sections had experienced some contact, while only Stuart and his small band had passed through the central section. Archival records concerning the Line’s construction and its first years of operation reveal a consistent pattern of engagement: an initial phase of avoidance and fear followed by direct confrontation and engagement, often by the same Aboriginal group. In both cases, the trigger was not necessarily the white man’s presence per se, but the unprecedented temptation of large amounts of a new and extraordinary resource, metal. Prudently, Charles Todd issued instructions minimising fraternisation, which repressed the growing appeal of European commodities and material; armed parties attacked three telegraph stations during the mid-1870s. A pax Britannica gradually ensued. This paper focuses upon the first ten years of Aboriginal interactions, proposing a sequence of dynamic engagement with Europeans, prefiguring the subsequent tightening control and dispossession of local Aboriginal groups along the length of the Line. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
117. Secularism and freedom of conscience
- Subjects
Secularism and Freedom of Conscience (Nonfiction work) -- Maclure, Jocelyn -- Taylor, Charles -- Todd, Jane Marie ,Books -- Book reviews ,Library and information science ,Publishing industry - Abstract
9780674058651Secularism and freedom of conscience.Maclure, Jocelyn and Charles Taylor. Trans. by Jane Marie Todd.Harvard University Press2011142 pages$24.95HardcoverBL2747Canadian scholars of philosophy Maclure (U. Laval) and Taylor (emeritus, McGill U.) set out [...]
- Published
- 2012
118. Response transformations in repeated measures and growth curve models
- Author
-
Charles Todd, Robert J. Boik, and Scott K. Hyde
- Subjects
Statistics and Probability ,Mixed model ,Estimation theory ,Scoring algorithm ,Likelihood-ratio test ,Statistics ,Covariance ,Growth curve (statistics) ,Statistical hypothesis testing ,Sphericity ,Mathematics - Abstract
This article describes estimation and inference procedures for the parameters of the Box-Cox and foided-power transformations in repeated measures and growth curve models. Procedures for computing maximum likelihood estimates of the transformation and covariance parameters under several covanance structures (omnibus sphericity, local sphericity, and unstructured) are described. Lack of fit statistics and hypothesis tests for comparing these structures also are described. The procedures are illustrated on three data sets. Software for performing the analyses in the SAS System is described and is available from the authors.
- Published
- 2000
119. Regulating the new
- Author
-
Nicholls, Rob
- Published
- 2023
120. Intermittent oral administration of potassium iodide solution for the correction of iodine deficiency
- Author
-
Charles Todd and John T Dunn
- Subjects
Male ,Zimbabwe ,medicine.medical_specialty ,Goiter ,Adolescent ,medicine.medical_treatment ,Thyroid Gland ,Administration, Oral ,Thyrotropin ,Medicine (miscellaneous) ,chemistry.chemical_element ,Iodine ,Drug Administration Schedule ,Group B ,Oral administration ,Internal medicine ,medicine ,Humans ,Child ,Nutrition and Dietetics ,Dose-Response Relationship, Drug ,business.industry ,Thyroid ,Potassium Iodide ,Iodized Oil ,medicine.disease ,Iodine deficiency ,Body Height ,Iodised salt ,Endocrinology ,medicine.anatomical_structure ,chemistry ,Female ,Thyroglobulin ,Deficiency Diseases ,business - Abstract
Iodized salt and iodized oil are the main methods used to prevent iodine deficiency, but sometimes alternative approaches are needed. We tested the efficacy of various regimens for the intermittent administration of potassium iodide in Hwedza, Zimbabwe, an area of known severe iodine deficiency. We divided 304 schoolchildren aged 7-13 y into five equal groups that received iodine as a 10% solution of potassium iodide as follows: 8.7 mg every 2 wk (group A), 29.7 mg every month (group B), 148.2 mg every 3 mo (group C), 382 mg every 6 mo (group D), or 993 mg once (group E). The follow-up period was 13 mo. No adverse effects were encountered with any of these doses. After 6 mo, the median blood spot thyroglobulin concentration had decreased in all groups and had normalized in groups A and B to values found in iodine-sufficient populations. The number of children with elevated thyroid-stimulating hormone concentrations decreased in groups A-C, but the changes were not significant. Urine iodine concentration generally remained low in all groups but increased in group A. After 13 mo, mean thyroid volume measured by ultrasound had decreased in groups A and B to values comparable with those in iodine-sufficient areas, and was unchanged in the other groups. We conclude that oral potassium iodide is effective for the prophylaxis of iodine deficiency if given as a dose of 30 mg I monthly or 8 mg biweekly.
- Published
- 1998
121. Discussion
- Author
-
Gregory Gerasimov, Chandrakant S. Pandav, Moulay Benmiloud, François M. Delange, and Charles Todd
- Subjects
Public aspects of medicine ,RA1-1270 - Full Text
- View/download PDF
122. Can general internal medicine be taught in general practice? An evaluation of the University College London model
- Author
-
Charles Todd, Michael Modell, and Elizabeth Murray
- Subjects
Adult ,Male ,Medical education ,Objective structured clinical examination ,business.industry ,education ,General Medicine ,Middle Aged ,Education ,Community Medicine ,London ,General practice ,ComputingMilieux_COMPUTERSANDEDUCATION ,Humans ,Medicine ,Female ,Clinical Competence ,Clinical competence ,Family Practice ,business ,Scientific disciplines ,Clinical skills ,Education, Medical, Undergraduate - Abstract
There is national and international interest in increasing the community-based component of undergraduate medical education, but more research is needed on its potential, practicability and effectiveness. The objective of the study was to examine the feasibility and efficacy of general practitioners teaching basic clinical skills to first year clinical medical students in the community. The structure and methods of evaluation of the programme are described. Evaluation tools included semistructured interviews of general practitioner tutors; student questionnaires; assessment of student performance; and costs of the programme. The great majority of the students found the programme enjoyable (81 out of 81, 100%) and educational (79 out of 81, 97%). Students' performance in the end of rotation Objective Structured Clinical Examination suggested that clinical skills are acquired at least as well in the community as in the hospital. Tutors identified the personal benefits of this teaching as development of their own clinical skills and the stimulation of teaching. The programme has been successfully expanded from 24 students to 230 students annually and has demonstrated that community-based teaching can usefully contribute to undergraduate medical education in the area of clinical skills teaching. Key practical issues for schools contemplating similar initiatives are presented.
- Published
- 1997
123. Maclure, Jocelyn and Charles Taylor. Secularism and Freedom of Conscience
- Author
-
Dougherty, Jude P.
- Subjects
Secularism and Freedom of Conscience (Nonfiction work) -- Maclure, Jocelyn -- Taylor, Charles -- Todd, Jane Marie -- Book reviews ,Books -- Book reviews ,Philosophy and religion - Abstract
MACLURE, Jocelyn and Charles Taylor. Secularism and Freedom of Conscience. Translated by Jane Marie Todd. Cambridge, MA: Harvard University Press, 2011. 160 pp. Cloth, $24.95--1n the early pages of the [...]
- Published
- 2011
124. THE GRADUATING CLASS OF THE MEDICAL COLLEGE OF GEORGIA.
- Author
-
QUINTARD, CHARLES TODD
- Subjects
LIFE ,WISDOM ,JOY ,GRIEF ,REPENTANCE ,ENEMIES - Abstract
The article focuses on several aspects of human life. It mentions about expanding beneath the teachings of wisdom, and with joys yet warming into life the enthusiasm of life's early dreams swept by the storms of sorrow, remorse and repentance. It also mentions about taking station in the world to do good or to do evil and to gain friends or enemies, honor or dishonor.
- Published
- 2018
125. Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation.
- Author
-
Shcherbik, Svetlana, Pearce, Nicholas, Balish, Amanda, Jones, Joyce, Thor, Sharmi, Davis, Charles Todd, Pearce, Melissa, Tumpey, Terrence, Cureton, David, Chen, Li-Mei, Villanueva, Julie, and Bousse, Tatiana L.
- Subjects
AVIAN influenza vaccines ,DEATH rate ,DRUG development ,IMMUNE response ,VIRAL replication ,GENETIC mutation ,VIRAL genomes ,VACCINE manufacturing - Abstract
Background: Avian influenza A (H7N9) virus has emerged recently and continues to cause severe disease with a high mortality rate in humans prompting the development of candidate vaccine viruses. Live attenuated influenza vaccines (LAIV) are 6:2 reassortant viruses containing the HA and NA gene segments from wild type influenza viruses to induce protective immune responses and the six internal genes from Master Donor Viruses (MDV) to provide temperature sensitive, cold-adapted and attenuated phenotypes. Methodology/Principal Findings: LAIV candidate A/Anhui/1/2013(H7N9)-CDC-LV7A (abbreviated as CDC-LV7A), based on the Russian MDV, A/Leningrad/134/17/57 (H2N2), was generated by classical reassortment in eggs and retained MDV temperature-sensitive and cold-adapted phenotypes. CDC-LV7A had two amino acid substitutions N123D and N149D (H7 numbering) in HA and one substitution T10I in NA. To evaluate the role of these mutations on the replication capacity of the reassortants in eggs, the recombinant viruses A(H7N9)RG-LV1 and A(H7N9)RG-LV2 were generated by reverse genetics. These changes did not alter virus antigenicity as ferret antiserum to CDC-LV7A vaccine candidate inhibited hemagglutination by homologous A(H7N9) virus efficiently. Safety studies in ferrets confirmed that CDC-LV7A was attenuated compared to wild-type A/Anhui/1/2013. In addition, the genetic stability of this vaccine candidate was examined in eggs and ferrets by monitoring sequence changes acquired during virus replication in the two host models. No changes in the viral genome were detected after five passages in eggs. However, after ten passages additional mutations were detected in the HA gene. The vaccine candidate was shown to be stable in the ferret model; post-vaccination sequence data analysis showed no changes in viruses collected in nasal washes present at day 5 or day 7. Conclusions/Significance: Our data indicate that the A/Anhui/1/2013(H7N9)-CDC-LV7A reassortant virus is a safe and genetically stable candidate vaccine virus that is now available for distribution by WHO to vaccine manufacturers. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
126. Association of Breast Cancer and Immune Thrombocytopenic Purpura
- Author
-
Charles Todd Bruker, Linda Hendricks, Russell Burgess, Paul M. Dainer, and Celalettin Ustun
- Subjects
Adult ,Oncology ,medicine.medical_specialty ,Mammary gland ,Breast Neoplasms ,Metastasis ,Breast cancer ,immune system diseases ,hemic and lymphatic diseases ,Internal medicine ,Immunopathology ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Carcinoma ,Humans ,skin and connective tissue diseases ,Glucocorticoids ,Purpura, Thrombocytopenic, Idiopathic ,business.industry ,Cancer ,General Medicine ,medicine.disease ,Metastatic breast cancer ,Thrombocytopenic purpura ,medicine.anatomical_structure ,Immunology ,Prednisone ,Female ,business - Abstract
Immune thrombocytopenic purpura (ITP) and breast cancer are common disorders. Only six cases in which patients have had both diseases have been reported. We describe a 40-year-old woman who had ITP while responding to therapy for metastatic breast cancer. Given the few reported cases, the diverse presentations of thrombocytopenia during the course of each patient's breast cancer and the variable therapeutic responses of ITP, the association of breast cancer and ITP is probably coincidental.
- Published
- 2002
127. Copd
- Author
-
Robert Andrew, McIvor, Marcel, Tunks, and David Charles, Todd
- Subjects
Pulmonary Disease, Chronic Obstructive ,Theophylline ,Respiratory Disorders (Chronic) ,Adrenal Cortex Hormones ,alpha 1-Antitrypsin ,Administration, Inhalation ,Humans ,Muscle Strength ,Adrenergic beta-Agonists ,urologic and male genital diseases ,respiratory tract diseases - Abstract
Chronic obstructive pulmonary disease (COPD) is a disease state characterised by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases. Classically, it is thought to be a combination of emphysema and chronic bronchitis, although only one of these may be present in some people with COPD. The main risk factor for the development and deterioration of COPD is smoking.We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of maintenance drug treatment in stable COPD? What are the effects of smoking cessation interventions in people with stable COPD? What are the effects of non-drug interventions in people with stable COPD? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).We found 119 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.In this systematic review, we present information relating to the effectiveness and safety of the following interventions: alpha(1) antitrypsin, antibiotics (prophylactic), anticholinergics (inhaled), beta(2) agonists (inhaled), corticosteroids (oral and inhaled), general physical activity enhancement, inspiratory muscle training, nutritional supplementation, mucolytics, oxygen treatment (long-term domiciliary treatment), peripheral muscle strength training, psychosocial and pharmacological interventions for smoking cessation, pulmonary rehabilitation, and theophylline.
- Published
- 2011
128. Lott Vows Another Cloture Vote On Bankruptcy Reform Bill
- Author
-
Hurley, Charles Todd And Maureen
- Subjects
United States. Senate -- Economic policy -- Planning ,Bankruptcy law -- Planning ,Government ,News, opinion and commentary ,Company business planning ,Planning ,Economic policy - Abstract
WASHINGTON -- Nov-2 -- (CongressDaily) Senate Majority Leader Lott Wednesday reaffirmed his plans to once again offer a motion to invoke cloture on a bankruptcy reform conference report by the [...]
- Published
- 2000
129. What is the way forward for health in Zimbabwe?
- Author
-
David Sanders, Farai D. Madzimbamuto, Charles Todd, and Sunanda Ray
- Subjects
Zimbabwe ,medicine.medical_specialty ,Population ,Community Health Planning ,Health Services Accessibility ,Environmental health ,Health care ,Global health ,Medicine ,Humans ,Social determinants of health ,Socioeconomics ,education ,Health policy ,education.field_of_study ,Health Services Needs and Demand ,Poverty ,business.industry ,Public health ,Health Policy ,Politics ,General Medicine ,Health promotion ,Social Conditions ,business ,Delivery of Health Care - Abstract
Zimbabwe’s Government of National Unity (GNU), established on Feb 13, 2009, faced immense challenges: a collapsed economy with 94% of the population without a job and almost 50% needing food aid; a severe cholera epidemic; HIV/AIDS prevalence of more than 15% in adults aged 15–49 years; and a collapsed health system. The GNU responded to the issues of the health sector by holding an inclusive summit and adopting an ambitious 100-day recovery plan for the health sector. Here, we describe the recent health crisis and its causes, and make proposals for an eff ective and sustainable health system. Zimbabwe was once a beacon of hope in Africa, improving health tremendously after independence in 1980. A declining national income, a huge national debt, economic structural adjustment, recurrent droughts, widespread HIV/AIDS, and a weakening health system all contributed to the deterioration of Zimbabweans’ health since 1990. Between 2000 and 2005, the gross national income (GNI) per head declined by 54%. The latest estimate of US$340 places Zimbabwe among the world’s poorest countries: all the income gains of the past 56 years have been wiped out. Economic decline has driven the exodus of Zimbabweans, with over 3 million of the total population of 13·5 million estimated to be living outside the country; the funds remitted by them are the main source of income for many families. For those having no access to external funds the situation is dire. Between 1990 and 2006, life expectancy at birth plummeted from 62 to 43 years, mostly from increased young adult mortality from HIV-related conditions. Mortality rates of children younger than 5 years and infants rose from 77 and 53 per 1000 livebirths in 1992 to 82 and 60 in 2003, respectively. Maternal mortality rose from 168 per 100 000 births in 1990 to 725 per 100 000 in 2007. Tuberculosis incidence increased from 136 per 100 000 in 1990 to 557 per 100 000 in 2006. These indicators are related to the high prevalence of HIV/ AIDS, which was estimated at 26% in 2000 in adults aged 15–45 years but declined to 15·3% by 2007. In 1994, 80·1% of children aged 12–23 months had received all basic vaccines compared with 74·8% in 1999 and only 52·6% in 2006–07. By early 2009, hospitals in the country were hardly operating, with massive shortages of essential medicines and supplies. Although most hospitals are now functioning again, shortages are still commonplace and patients usually need to buy medicines, intravenous fl uids, and sutures. Women delivering in rural clinics must bring candles, cotton wool, methylated spirit, gloves, and even fresh water. The physical infrastructure of most government health facilities is decrepit, and ambulances sparse. The recent cholera outbreak further exposed Zimbabwe’s collapsed infrastructure and its health system. Between August, 2008, and July, 2009, 98 591 suspected cholera cases were reported, including 4288 deaths. The epidemic resulted from the breakdown of urban water and sanitation systems, leading to contamination of piped water and shallow wells. The case-fatality rate peaked at almost 6%, greatly exceeding the 1% WHO norm, indicating the weakened health system and poor access in rural areas. Total health expenditure per head fell by 56% between 2000 and 2005 to $21, of which $9 was government expenditure. External funding contributed 21% of total health spending, a low proportion compared with that in most African countries. Under the previous government, which was led by Zimbabwe African National UnionPatriotic Front (ZANU-PF) party, bilateral donors channelled funds to specifi c activities such as HIV programmes and family planning. Therefore, 58% of currently married women use modern contraceptive methods, and about 100 000 people were receiving antiretroviral treatment by the end of 2007. However, antiretroviral treatment coverage at 17% is the lowest of any country in southern Africa, with an estimated 570 000 people needing treatment. Furthermore, HIVpositive patients displaced by political violence and those aff ected by stock-outs of common AIDS medicines or closure of treatment facilities have been unable to reestablish treatment. In 2005, Zimbabwe was losing an estimated 20% of its health-care professionals every year; 18 000 nurses have left since 1998. Although some heroically continued to work for minimal rewards, by the end of 2008 many had stopped working. By this time, a government doctor’s salary had fallen to less than $1 per month. Many health workers witnessed violence and some were harassed for treating victims of violence. Health training in Zimbabwe has suff ered badly and the country’s principal medical school—the College of Health Sciences of the University of Zimbabwe in Harare—closed from November, 2008, to May, 2009. Only 40% of academic posts are fi lled; Bulawayo’s new medical school faces even greater staff shortages. Nursing and midwifery schools struggle with 60% of nurse tutor posts vacant. Disregard for human rights has long featured in Zimbabwe’s history. After the elections in March, 2008, thousands of people were beaten or tortured in an attempt to subdue support for the opposition. Political abductions and intimidation continue despite the establishment of the GNU. National recovery cannot take place without addressing human rights and ending the culture of impunity. To restore Zimbabwe’s health sector, the priority must be to meet the population’s most urgent health needs by Lancet 2010; 375: 606–09
- Published
- 2009
130. Charles Todd.
- Published
- 2011
131. CHARLES TODD.
- Published
- 2000
132. Watchers of Time : An Inspector Ian Rutledge Novel
- Author
-
Charles Todd and Charles Todd
- Subjects
- Rutledge, Ian (Fictitious character)--Fiction, Police--England--Fiction
- Abstract
“If anyone can turn a simple village mystery into a brooding Greek tragedy, it's Charles Todd.... Todd handles grave issues with great compassion”—The New York Times Book Review In a marshy Norfolk backwater, a priest is brutally murdered after giving a dying man last rites. For Scotland Yard's Ian Rutledge, an ex-officer still recovering from the trauma of war, it looks to be a simple case. Yet the Inspector finds himself uncovering secrets that the local authorities would prefer not to see explored. Rutledge pares away layers of deception to piece together a chain of events that stretches from the brooding marshes to one of the greatest sea disasters in history—the sinking of the Titanic. Who is the mysterious woman who may have boarded that ship—and who is the secretive woman who survived it? Only Rutledge can answer those questions... and prevent a killer who'll stop at nothing from striking again. Praise for Watchers of Time“One of the best historical series being written today... In the grand tradition of English murder mysteries.”—The Washington Post Book World“With his tortured detective Ian Rutledge and the ghost who inhabits his mind... Charles Todd has swiftly become one of the most respected writers in the mystery genre.... The pair is unique among sleuths.”—The Denver Post “Outstanding. Todd's portrait of Rutledge and postwar England remains powerful.”—Alfred Hitchcock Mystery Magazine
- Published
- 2001
133. Adapting our political institutions to a multicultural world
- Author
-
McManus, Liz
- Subjects
Secularism and Freedom of Conscience (Nonfiction work) -- Maclure, Jocelyn -- Taylor, Charles -- Todd, Jane Marie -- Book reviews ,Books -- Book reviews ,Family and marriage ,Philosophy and religion ,Women's issues/gender studies - Abstract
Secularism and Freedom of Conscience Jocelyn Maclure and Charles Taylor Translated from the French by Jane Marie Todd (Harvard University Press, 2011, 160 pp) 978-067405865I, $24.95 WHEN I WAS A [...]
- Published
- 2012
134. The Cultural Ideology of the Great War-Haunted British Detective in Historical Crime Fiction.
- Author
-
Sokołowska-Paryż, Marzena
- Subjects
HISTORICAL fiction ,MYSTERY fiction ,WORLD War I ,LITERARY form ,DETECTIVES ,GHOST stories ,WAR stories - Abstract
This article examines the cultural ideology underlying the constructions of the warhaunted detective in the historical crime fiction series by Rennie Airth, Jonathan Hicks, Charles Todd, and Jacqueline Winspear. These (re)imaginings of the Great War demonstrate the capacity of this literary genre to perpetuate the futility myth in the contemporary cultural memory of the 1914-18 British experience. [ABSTRACT FROM AUTHOR]
- Published
- 2022
135. A High Prevalence of Hypothyroidism in Association with Endemic Goitre in Zimbabwean Schoolchildren
- Author
-
Charles Todd and David Sanders
- Subjects
Zimbabwe ,endocrine system ,medicine.medical_specialty ,Goiter ,Adolescent ,endocrine system diseases ,Thyrotropin ,Physiology ,Thyroid function tests ,Child health ,Endemic goitre ,Hypothyroidism ,Thyroid-stimulating hormone ,Internal medicine ,Prevalence ,Humans ,Medicine ,Child ,medicine.diagnostic_test ,business.industry ,medicine.disease ,Thyroxine ,Infectious Diseases ,Endocrinology ,El Niño ,Pediatrics, Perinatology and Child Health ,Thyroid function ,business ,Goiter, Endemic - Abstract
One-hundred-and-eighty-eight ostensibly normal, pubertal schoolchildren, aged 9-16 years, residing in Chinamora Communal Land, Zimbabwe, had blood taken to assess thyroid function. Total goitre rate in the area was 44 per cent in primary schoolchildren: 91 of the subjects tested were goitrous. Thyroid stimulating hormone levels (TSH) were above normal (5.0 mu/l) in 66 subjects overall, of whom 39 were goitrous. The 36 subjects with TSH levels above 7.0 mu/l also had total thyroxine (T4) estimations performed: of these, 19 were below 60 nmol/l. The results indicate a high prevalence of hypothyroidism in this at risk group. The implications of these results are discussed, notably the impairment of mental function that is likely to result.
- Published
- 1991
136. 20090312 Equinox Mar 12 2009
- Author
-
Philbert, Bradley; Morehouse, Nancy; Mest, Elliott; Ogilvie, Zoe; Thai, Jon; Agba, Koffi; Tanaka, Yoshie; Cadet, Jillian; Xia, Ran; Imbimbo, Charles; Todd, James; Keochgerien, Lourdes; Ali, Abdul-Aziz; Maher, Matt; Vitale, Christine; Stein, Kathy; Jones, Sarah; Spence, Carl; Curti, Lisa-Marie and Philbert, Bradley; Morehouse, Nancy; Mest, Elliott; Ogilvie, Zoe; Thai, Jon; Agba, Koffi; Tanaka, Yoshie; Cadet, Jillian; Xia, Ran; Imbimbo, Charles; Todd, James; Keochgerien, Lourdes; Ali, Abdul-Aziz; Maher, Matt; Vitale, Christine; Stein, Kathy; Jones, Sarah; Spence, Carl; Curti, Lisa-Marie
- Abstract
Teaneck edition; Frequency varies
- Published
- 2009
137. Legacy of the Dead
- Author
-
Charles Todd and Charles Todd
- Subjects
- Rutledge, Ian (Fictitious character)--Fiction, Police--Scotland--Fiction
- Abstract
The weathered remains found on a Scottish mountainside may be those of Eleanor Gray, but the imperious Lady Maude Gray, Eleanor's mother, will have to be handled delicately. This is not the only ground that Inspector Ian Rutledge of Scotland Yard must tread carefully, for the case will soon lead him to Scotland, where many of Rutledge's ghosts rest uneasily. But it is an unexpected encounter that will hold the most peril.For in Scotland Rutledge will find that the young mother accused of killing Eleanor Gray is a woman to whom he owes a terrible debt. And his harrowing journey to find the truth will lead him back through the fires of his past, into secrets that still have the power to kill.
- Published
- 2007
138. Postgraduate district hospital training in Zambia
- Author
-
R.O. Laing and Charles Todd
- Subjects
medicine.medical_specialty ,business.industry ,Zambia ,General Medicine ,Training (civil) ,Physician Executives ,Nursing ,Education, Medical, Graduate ,District hospital ,Family medicine ,Medicine ,Humans ,business ,Public Health Administration ,Health Services Administration - Published
- 1993
139. Technical note: computing tests of fixed effects in a restricted class of mixed models
- Author
-
Robert J. Boik, Charles Todd, and M. W. Tess
- Subjects
Mixed model ,Generalized inverse ,Covariance matrix ,Linear model ,Explained sum of squares ,General Medicine ,Random effects model ,Models, Biological ,Statistics ,Genetics ,Linear Models ,Applied mathematics ,Animals ,Animal Science and Zoology ,Statistical theory ,Animal Husbandry ,Coefficient matrix ,Algorithms ,Food Science ,Mathematics - Abstract
Inferences about fixed effects in mixed linear models are important in a variety of animal science studies. The statistical theory for making such inferences is well known, and if the variance components are known up to a proportional- ity constant, then optimal exact tests can be per- formed. Computing the test statistics, however, can still be problematic when the random effects have many levels. In practice, approximate tests that are easily computed but less efficient are usually em- ployed. This article describes reduction in error sum of squares procedures for performing the exact test and for computing associated confidence intervals. By taking advantage of iterative algorithms for solving Henderson's mixed-model equations, the tests can be performed without inverting the covariance matrix or computing a generalized inverse of the mixed-model coefficient matrix. The procedures are illustrated on an animal model that has three random effects, two with 1,372 levels and one with 450 levels.
- Published
- 1993
140. New methodology for the synthesis of unsaturated hydroperoxides. Total synthesis of chondrillin and enantio-plakorin
- Author
-
Eary, Charles Todd and Eary, Charles Todd
- Abstract
The formation of organic peroxides is important to several normal biological processes, such as, fatty acid metabolism, prostaglandin synthesis and steroid synthesis. Lipid peroxidation has also been linked with detrimental biological processes and conditions, such as, aging, disease, and cancer. At present, a great deal of the biological consequences of lipid peroxidation remain unknown because of the inability to isolate or prepare suitable quantities of the desired peroxides. In addition, to lipid peroxidation several peroxide and hydroperoxide containing compounds have shown therapeutic potential, as antimalarial, antifungal, or anticancer agents. The large number of biologically active peroxide containing compounds has brought growing awareness of the need for improved tools for peroxide synthesis. As part of a research program targeting the stereoselective synthesis of peroxides, we investigated the reaction of allylstannanes and allylsilanes with singlet oxygen. Our investigations on several substrate systems have shown that allylstannanes undergo regioselective dioxygenation to produce hydroperoxy alkenylstannanes as the major product. Our results indicate that allylsilanes are inferior to allylstannanes as directing groups, and a reversal of abstraction regioselectivity is observed for Z-allylsilanes. We also explored the synthetic utility of vinylstannane hydroperoxides derived through the singlet oxygenation of allylstannanes. We were able to efficiently transform peroxy alkenylstannanes into peroxy vinyl iodides, which compelled us into investigating palladium-catalyzed cross-coupling reactions, as a new unprecedented modular approach to peroxide synthesis. We demonstrate that functionalized peroxides successfully participate in a wide variety of palladium-catalyzed carbon-carbon bond forming reactions, allowing an efficient synthesis of peroxyenones, peroxydienes, peroxyenoates, and peroxyenals. An alternative strategy was undertaken for the first enant
- Published
- 1998
141. QUINTARD, Charles Todd.
- Published
- 1891
142. The effect of axial ligands and porphyrin substituents on the electronic ground state of low-spin iron(III) porphyrinates
- Author
-
Watson, Charles Todd, 1967 and Watson, Charles Todd, 1967
- Abstract
To aid in the understanding of the electronic states of low-spin, bis-pyridine and -imidazole model complexes of the cytochromes b variable temperature proton NMR spectroscopy and EPR spectroscopy have been employed on a series of complexes of tetramesitylporphinatoiron(III), tetra(2,6-dibromophenyl)porphinatoiron(III) perchlorate, tetra(2,6-dichlorophenyl)porphinatoiron(III) perchlorate, tetra(2,6-difluorophenyl)porphin-atoiron(III) perchlorate, and tetra(2,6-dimethoxyphenyl)-porphinatoiron(III) perchlorate where the axial ligands were 4-dimethylaminopyridine, 3,4-dimethylpyridine, 3,5-dimethylpyridine, 4-methylpyridine, 3-methylpyridine, methylpyridine, 3-chloropyridine, 3-cyanopyridine, 4-cyanopyridine, N-methylimidazole, and 2-methylimidazole. Both paramagnetic iron(III) and diamagnetic cobalt(III) porphyrinates were synthesized. The 25°C proton NMR spectra of the cobalt(III) complexes were used to estimate the diamagnetic shifts of the corresponding iron(III) complexes. The proton NMR spectra of the iron(III) complexes were recorded from -90°C to +40°C. Small isotropic shifts and anti-Curie behavior in the pyrrole-proton resonances of the lower basicity pyridine complexes of tetramesitylporphinatoiron(III)+ indicate a (dxz,dyz)⁴(dxy)¹ ground state, and axial ∼4K EPR spectra of the lower basicity complexes and large gmax or rhombic EPR spectra of the higher basicity pyridine complexes of all of the iron(III) porphyrinates studied indicate a shift in electronic ground state from (dxz,dyz)⁴(dxy)¹ for the lower basicity pyridine complexes to (dxy)²(dxz,dyz)³ for the higher basicity pyridine complexes in all cases. The dipolar and contact contributions to the isotropic shift were determined based on estimates of the ground-excited state crossover point and geometric factors obtained from crystal structure data. Variable temperature NOESY and COSY spectra were successful in distinguishing meta from para resonances in the NMR spectra of the tetra-(2,6-dichlorophenyl)p
- Published
- 1996
143. Increase in thyrotoxicosis associated with iodine supplements in Zimbabwe
- Author
-
Emily Oken, Charles Todd, T. Allain, M. Ndiweni, J.A. Hasler, and Z.A.R. Gomo
- Subjects
medicine.medical_specialty ,Pediatrics ,Endocrinology ,chemistry ,business.industry ,Internal medicine ,Incidence (epidemiology) ,medicine ,MEDLINE ,chemistry.chemical_element ,General Medicine ,business ,Iodine - Published
- 1995
144. A Cold Treachery
- Author
-
Charles Todd and Charles Todd
- Subjects
- Police--England--Fiction, Rutledge, Ian (Fictitious character)--Fiction, Mass murder investigation--Fiction, Missing children--Fiction, Child witnesses--Fiction
- Abstract
“Stunning... the tragic sweep of Todd's historical mysteries grows more expansive with each novel.”—The New York Times Book ReviewCalled out into the teeth of a violent blizzard, Inspector Ian Rutledge faces one of the most savage murders he's ever encountered. He might have expected such unspeakable carnage on the World War I battlefields where he'd lost much of his soul—and his sanity—but not in an otherwise peaceful farm kitchen in remote Urskdale. Someone has murdered the Elcott family without the least sign of struggle. But when the victims are tallied, the local police are in for another shock: One child is missing. Now the Inspector must race to save a young boy before he's silenced by the merciless elements—or the even colder hands of the killer who hides in the blinding snow. Praise for A Cold Treachery“Todd's Ian Rutledge mysteries are among the most intelligent and affecting being written these days.”—Washington Post Book World“Brilliant.”—Chicago Tribune“Traditional mystery lovers who prefer their whodunits enriched with psychological insight will heartily embrace A Cold Treachery.... A superb effort.”—Publishers Weekly (starred review)“Brilliantly conceived and elegantly executed.”—Strand magazine
- Published
- 2005
145. Behind the Legend: The Many Worlds of Charles Todd.
- Author
-
Zion, Lawrie
- Subjects
NONFICTION - Published
- 2018
- Full Text
- View/download PDF
146. HIV/AIDS epidemiology
- Author
-
Charles Todd
- Subjects
medicine.medical_specialty ,Acquired immunodeficiency syndrome (AIDS) ,Cost–benefit analysis ,business.industry ,Environmental health ,Public health ,Epidemiology ,medicine ,Developing country ,General Medicine ,Treatment costs ,medicine.disease ,business - Published
- 2000
147. QUINTARD, Charles Todd.
- Published
- 1903
148. Accounting. (Movers & Shakers)
- Subjects
Tullius Taylor Sartain and Sartain L.L.P. -- Officials and employees ,Accounting firms -- Officials and employees ,Business ,Business, regional ,Arkansas Society of Certified Public Accountants -- Achievements and awards - Abstract
Phyllis A. Holifield of Little Rock has been given the 2002 Arkansas Society of Certified Public Accountants Public Service Award. Holifield is president of Priddy and Holifield CPAs P.A. of [...]
- Published
- 2002
149. The Murder Stone : A Novel of Suspense
- Author
-
Charles Todd and Charles Todd
- Subjects
- Revenge--Fiction, Women--England--Fiction, World War, 1914-1918--England--Fiction, Grandfathers--Death--Fiction, Inheritance and succession--Fiction
- Abstract
“A stunner, exquisitely plotted and characterized, with Todd's trademark meticulous backdrop of World War I-era England.”—Strand MagazineThe Great War is still raging when Francesca Hatton's adored grandfather dies on the family estate in England's isolated Exe Valley. Among his effects, Francesca is stunned to find an unsigned letter cursing the Hattons and their descendants. Then a stranger appears, accusing her grandfather of murder. Was the loving protector Francesca remembers really a vindictive man who cultivated dangerous enemies? At the center of the intrigue is an unusual white stone hidden in a garden where Francesca once played with her five male cousins—all dead now on France's battlefields. According to Hatton's will, the Murder Stone must be dug up, transported to Scotland, and buried forever. But before Francesca can begin the journey, a series of ominous “accidents” occur. As Francesca sets out to pursue the truth, she also sets herself in the sights of someone determined to exact a revenge too long overdue. Praise for The Murder Stone“Todd's mysteries are among the most intelligent and affecting being written these days.”—Washington Post Book World “Seamless... a compelling insight into the home front during 1916.”—Chicago Tribune“A gripping novel of family secrets set against the tragedy of World War I.”—Mystery Lovers Bookshop News “Many twists and turns, angst-ridden characters, and an evocative historical setting. A gripping read.”—Library Journal
- Published
- 2003
150. Think before donating medical supplies
- Author
-
Charles Todd
- Subjects
medicine.medical_specialty ,business.industry ,Third world ,medicine.drug_class ,General Engineering ,Alternative medicine ,General Medicine ,medicine.disease ,Decongestant ,General Earth and Planetary Sciences ,Medicine ,Letters ,Medical emergency ,business ,General Environmental Science - Abstract
Editor,--I would urge that donations of medical supplies to Third World countries should be chosen just as carefully as those to the former Yugoslavia.1 In Zimbabwe I worked at a mission hospital where some of the donations we received included lorazepam, drops for infant colic, and decongestant …
- Published
- 1994
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