21,192 results on '"Binns, A."'
Search Results
102. African Economies
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Binns, Tony, primary, Nel, Etienne, additional, Dixon, Alan, additional, and Lynch, Kenneth, additional
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- 2023
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103. Conflict and Post-Conflict
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Binns, Tony, primary, Nel, Etienne, additional, Dixon, Alan, additional, and Lynch, Kenneth, additional
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- 2023
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104. Developing Africa
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Binns, Tony, primary, Nel, Etienne, additional, Dixon, Alan, additional, and Lynch, Kenneth, additional
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- 2023
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105. Energy
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Binns, Chelsea A., primary
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- 2023
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106. A retrospective observational study on characteristics, treatment patterns, and healthcare resource use of patients with myasthenia gravis in England
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Jordy van Enkhuizen, Jean Binns, April Betts, Fatemeh Saberi Hosnijeh, Myriam Alexander, Mark McCormack, and Saiju Jacob
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Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Background: There are limited data on the real-world healthcare resource use (HCRU) and management costs of myasthenia gravis (MG) in England. Objective: This study aims to assess the burden of disease for patients with MG in England. Design: A retrospective, observational cohort study of adult patients diagnosed with MG, using data from the Hospital Episode Statistics data warehouse. Methods: Patients with a first-ever recorded diagnosis of MG between 30 June 2015 and 30 June 2020 were followed up until 30 June 2021 or death, whichever occurred first. Post-diagnosis patient characteristics, treatment patterns, HCRU, and costs were described. Costs were evaluated using National Health Service reference costs. Results: A total of 9087 patients with a median follow-up time of 2.9 years (range, 1.7–4.3 years) were included. The mean age at diagnosis was 66.5 years and 53% of the patients were male. A large proportion of patients (72.8%) were admitted as inpatients during follow-up with a mean number of 1.3 admissions. Patients hospitalized for MG-related complications spent a mean of 9.7 days per patient-year in the hospital. During follow-up, 599 (6.6% of the total cohort) and 163 (1.8%) patients had a record of rescue therapy with intravenous immunoglobulin (IVIg) and plasma exchange (PLEX), respectively. Rituximab was administered to 81 (0.9%) patients and 268 (2.9%) patients underwent thymectomy. In those patients receiving rescue therapy or rituximab, >10% received at least three cycles of the same treatment. The average annual cost of hospital admissions across all patients treated with IVIg, PLEX, and rituximab were £907,072, £689,979, and £146,726, respectively. Conclusion: A majority of MG patients required hospitalization or accident and emergency attendance, resulting in high HCRU and costs. A subset of patients required rescue therapy (including IVIg and PLEX), rituximab administration, ventilation, or thymectomy.
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- 2024
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107. Direct Measurement of the Cosmic-Ray Carbon and Oxygen Spectra from 10 GeV$/n$ to 2.2 TeV$/n$ with the Calorimetric Electron Telescope on the International Space Station
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Adriani, O., Akaike, Y., Asano, K., Asaoka, Y., Bagliesi, M. G., Berti, E., Bigongiari, G., Binns, W. R., Bongi, M., Brogi, P., Bruno, A., Buckley, J. H., Cannady, N., Castellini, G., Checchia, C., Cherry, M. L., Collazuol, G., Ebisawa, K., Fuke, H., Gonzi, S., Guzik, T. G., Hams, T., Hibino, K., Ichimura, M., Ioka, K., Ishizaki, W., Israel, M. H., Kasahara, K., Kataoka, J., Kataoka, R., Katayose, Y., Kato, C., Kawanaka, N., Kawakubo, Y., Kobayashi, K., Kohri, K., Krawczynski, H. S., Krizmanic, J. F., Link, J., Maestro, P., Marrocchesi, P. S., Messineo, A. M., Mitchell, J. W., Miyake, S., Moiseev, A. A., Mori, M., Mori, N., Motz, H. M., Munakata, K., Nakahira, S., Nishimura, J., de Nolfo, G. A., Okuno, S., Ormes, J. F., Ospina, N., Ozawa, S., Pacini, L., Palma, F., Papini, P., Rauch, B. F., Ricciarini, S. B., Sakai, K., Sakamoto, T., Sasaki, M., Shimizu, Y., Shiomi, A., Sparvoli, R., Spillantini, P., Stolzi, F., Sugita, S., Suh, J. E., Sulaj, A., Takita, M., Tamura, T., Terasawa, T., Torii, S., Tsunesada, Y., Uchihori, Y., Vannuccini, E., Wefel, J. P., Yamaoka, K., Yanagita, S., Yoshida, A., and Yoshida, K.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
In this paper, we present the measurement of the energy spectra of carbon and oxygen in cosmic rays based on observations with the Calorimetric Electron Telescope (CALET) on the International Space Station from October 2015 to October 2019. Analysis, including the detailed assessment of systematic uncertainties, and results are reported. The energy spectra are measured in kinetic energy per nucleon from 10 GeV$/n$ to 2.2 TeV$/n$ with an all-calorimetric instrument with a total thickness corresponding to 1.3 nuclear interaction length. The observed carbon and oxygen fluxes show a spectral index change of $\sim$0.15 around 200 GeV$/n$ established with a significance $>3\sigma$. They have the same energy dependence with a constant C/O flux ratio $0.911\pm 0.006$ above 25 GeV$/n$. The spectral hardening is consistent with that measured by AMS-02, but the absolute normalization of the flux is about 27% lower, though in agreement with observations from previous experiments including the PAMELA spectrometer and the calorimetric balloon-borne experiment CREAM., Comment: main text: 7 pages, 3 figures; supplemental material: 20 pages, 15 figures, 3 tables
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- 2020
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108. Knot Floer homology, link Floer homology and link detection
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Binns, Fraser and Martin, Gage
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Mathematics - Geometric Topology ,57K18, 57K10 - Abstract
We give new link detection results for knot and link Floer homology inspired by recent work on Khovanov homology. We show that knot Floer homology detects $T(2,4)$, $T(2,6)$, $T(3,3)$, $L7n1$, and the link $T(2,2n)$ with the orientation of one component reversed. We show link Floer homology detects $T(2,2n)$ and $T(n,n)$, for all $n$. Additionally we identify infinitely many pairs of links such that both links in the pair are each detected by link Floer homology but have the same Khovanov homology and knot Floer homology. Finally, we use some of our knot Floer detection results to give topological applications of annular Khovanov homology.
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- 2020
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109. A search for ultrahigh-energy neutrinos associated with astrophysical sources using the third flight of ANITA
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Deaconu, C., Batten, L., Allison, P., Banerjee, O., Beatty, J. J., Belov, K., Besson, D. Z., Binns, W. R., Bugaev, V., Cao, P., Chen, C. H., Chen, P., Chen, Y., Clem, J. M., Connolly, A., Cremonesi, L., Dailey, B., Dowkontt, P. F., Fox, B. D., Gordon, J. W. H., Gorham, P. W., Hast, C., Hill, B., Hsu, S. Y., Huang, J. J., Hughes, K., Hupe, R., Israel, M. H., Liewer, K. M., Liu, T. C., Ludwig, A. B., Macchiarulo, L., Matsuno, S., McBride, K., Miki, C., Mulrey, K., Nam, J., Naudet, C., Nichol, R. J., Novikov, A., Oberla, E., Prohira, S., Prechelt, R., Rauch, B. F., Ripa, J., Roberts, J. M., Romero-Wolf, A., Rotter, B., Russell, J. W., Saltzberg, D., Seckel, D., Schoorlemmer, H., Shiao, J., Stafford, S., Stockham, J., Stockham, M., Strutt, B., Sutherland, M. S., Varner, G. S., Vieregg, A. G., Wang, N., Wang, S. H., and Wissel, S. A.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics ,High Energy Physics - Experiment - Abstract
The ANtarctic Impulsive Transient Antenna (ANITA) long-duration balloon experiment is sensitive to interactions of ultra high-energy (E > 10^{18} eV) neutrinos in the Antarctic ice sheet. The third flight of ANITA, lasting 22 days, began in December 2014. We develop a methodology to search for energetic neutrinos spatially and temporally coincident with potential source classes in ANITA data. This methodology is applied to several source classes: the TXS 0506+056 blazar and NGC 1068, the first potential TeV neutrino sources identified by IceCube, flaring high-energy blazars reported by the Fermi All-Sky Variability Analysis, gamma-ray bursts, and supernovae. Among searches within the five source classes, one candidate was identified as associated with SN 2015D, although not at a statistically significant level. We proceed to place upper limits on the source classes. We further comment on potential applications of this methodology to more sensitive future instruments., Comment: 23 pages, 7 figures, version accepted to JCAP
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- 2020
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110. Experimental tests of sub-surface reflectors as an explanation for the ANITA anomalous events
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Smith, D., Besson, D. Z., Deaconu, C., Prohira, S., Allison, P., Batten, L., Beatty, J. J., Binns, W. R., Bugaev, V., Cao, P., Chen, C., Chen, P., Clem, J. M., Connolly, A., Cremonesi, L., Dasgupta, P., Gorham, P. W., Israel, M. H., Liu, T. C., Ludwig, A., Matsuno, S., Miki, C., Nam, J., Novikov, A., Nichol, R. J., Oberla, E., Prechelt, R., Rauch, B. F., Russell, J., Saltzberg, D., Seckel, D., Varner, G. S., Vieregg, A. G., and Wissel, S. A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The balloon-borne ANITA experiment is designed to detect ultra-high energy neutrinos via radio emissions produced by an in-ice shower. Although initially purposed for interactions within the Antarctic ice sheet, ANITA also demonstrated the ability to self-trigger on radio emissions from ultra-high energy charged cosmic rays interacting in the Earth's atmosphere. For showers produced above the Antarctic ice sheet, reflection of the down-coming radio signals at the Antarctic surface should result in a polarity inversion prior to subsequent observation at the $\sim$35-40 km altitude ANITA gondola. ANITA has published two anomalous instances of upcoming cosmic-rays with measured polarity opposite the remaining sample of $\sim$50 UHECR signals. The steep observed upwards incidence angles (25--30 degrees relative to the horizontal) require non-Standard Model physics if these events are due to in-ice neutrino interactions, as the Standard Model cross-section would otherwise prohibit neutrinos from penetrating the long required chord of Earth. Shoemaker et al. posit that glaciological effects may explain the steep observed anomalous events. We herein consider the scenarios offered by Shoemaker et al. and find them to be disfavored by extant ANITA and HiCal experimental data. We note that the recent report of four additional near-horizon anomalous ANITA-4 events, at $>3\sigma$ significance, are incompatible with their model, which requires significant signal transmission into the ice.
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- 2020
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111. Unusual Near-horizon Cosmic-ray-like Events Observed by ANITA-IV
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ANITA Collaboration, Gorham, P. W., Ludwig, A., Deaconu, C., Cao, P., Allison, P., Banerjee, O., Batten, L., Bhattacharya, D., Beatty, J. J., Belov, K., Binns, W. R., Bugaev, V., Chen, C. H., Chen, P., Chen, Y., Clem, J. M., Cremonesi, L., Dailey, B., Dowkontt, P. F., Fox, B. D., Gordon, J. W. H., Hast, C., Hill, B., Hsu, S. Y., Huang, J. J., Hughes, K., Hupe, R., Israel, M. H., Liu, T. C., Macchiarulo, L., Matsuno, S., McBride, K., Miki, C., Nam, J., Naudet, C. J., Nichol, R. J., Novikov, A., Oberla, E., Olmedo, M., Prechelt, R., Prohira, S., Rauch, B. F., Roberts, J. M., Romero-Wolf, A., Rotter, B., Russell, J. W., Saltzberg, D., Seckel, D., Schoorlemmer, H., Shiao, J., Stafford, S., Stockham, J., Stockham, M., Strutt, B., Sutherland, M. S., Varner, G. S., Vieregg, A. G., Wang, S. H., and Wissel, S. A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
ANITA's fourth long-duration balloon flight in late 2016 detected 29 cosmic-ray (CR)-like events on a background of $0.37^{+0.27}_{-0.17}$ anthropogenic events. CRs are mainly seen in reflection off the Antarctic ice sheets, creating a characteristic phase-inverted waveform polarity. However, four of the below-horizon CR-like events show anomalous non-inverted polarity, a $p = 5.3 \times 10^{-4}$ chance if due to background. All anomalous events are from locations near the horizon; ANITA-IV observed no steeply-upcoming anomalous events similar to the two such events seen in prior flights., Comment: 6 pages, 4 figures, to appear in Physical Review Letters. Supplemental material (reference 17) available from corresponding author
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- 2020
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112. On the detection of surface spin freezing in iron oxide nanoparticles and its long-term evolution under ambient oxidation
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Ghoshani, M., Sánchez, E. H., Lee, S. S., Singh, G., Yaacoub, N., Peddis, D., Mozaffari, M., Binns, C., De Toro, J. A., and Normile, P. S.
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Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Exchange bias effects linked to surface spin freezing (SSF) are commonly found in iron oxide nanoparticles, while signatures of SSF in low-field temperature-dependent magnetization curves have been much less frequently reported. Here, we present magnetic properties of dense assemblies of similar-sized (~ 8 nm diameter) particles synthesized by a magnetite (sample S1) and a maghemite (sample S2) method, and the influence of long-term (4-year) sample aging under ambient conditions on these properties. The size of the exchange bias field of the different sample (fresh or aged) states is found to correlate with (a) whether a low-temperature hump feature signaling the SSF transition is detected in out-of-phase ac susceptibility or zero-field-cooled (ZFC) dc magnetization recorded at low field and with (b) the prominence of irreversibility between FC and ZFC curves recorded at high field. Sample S1 displays a lower magnetization than S2, and it is in S1 where the largest SSF effects are found. These effects are significantly weakened by aging but remain larger than the SSF effects in S2, where the influence of aging is considerably smaller. A non-saturating component due to spin disorder in S1 also weakens with aging, accompanied by, we infer, an increase in the superspin and the radius of the ordered nanoparticle cores. X-ray diffraction and M\"ossbauer spectroscopy provide indication of maghemite-like stoichiometry in both aged samples as well as thicker disordered particle shells in aged-S1 relative to aged-S2 (crystallographically-disordered and spin-disordered according to diffraction and M\"ossbauer, respectively). The pronounced diminution in SSF effects with aging in S1 is attributed to a (long-term) transition, caused by ambient oxidation, from magnetite-like to maghemite-like stoichiometry, and a concomitant softening of the spin-disordered shell anisotropy..., Comment: 29 pages including main manuscript (18 pages, 6 figures, 2 tables) and supplementary material (pp. 19-29). Submitted to Nanotechnology (IOP series) on 13-Aug-2020
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- 2020
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113. Decentralized Privacy-Preserving Proximity Tracing
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Troncoso, Carmela, Payer, Mathias, Hubaux, Jean-Pierre, Salathé, Marcel, Larus, James, Bugnion, Edouard, Lueks, Wouter, Stadler, Theresa, Pyrgelis, Apostolos, Antonioli, Daniele, Barman, Ludovic, Chatel, Sylvain, Paterson, Kenneth, Čapkun, Srdjan, Basin, David, Beutel, Jan, Jackson, Dennis, Roeschlin, Marc, Leu, Patrick, Preneel, Bart, Smart, Nigel, Abidin, Aysajan, Gürses, Seda, Veale, Michael, Cremers, Cas, Backes, Michael, Tippenhauer, Nils Ole, Binns, Reuben, Cattuto, Ciro, Barrat, Alain, Fiore, Dario, Barbosa, Manuel, Oliveira, Rui, and Pereira, José
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Computer Science - Cryptography and Security ,Computer Science - Computers and Society - Abstract
This document describes and analyzes a system for secure and privacy-preserving proximity tracing at large scale. This system, referred to as DP3T, provides a technological foundation to help slow the spread of SARS-CoV-2 by simplifying and accelerating the process of notifying people who might have been exposed to the virus so that they can take appropriate measures to break its transmission chain. The system aims to minimise privacy and security risks for individuals and communities and guarantee the highest level of data protection. The goal of our proximity tracing system is to determine who has been in close physical proximity to a COVID-19 positive person and thus exposed to the virus, without revealing the contact's identity or where the contact occurred. To achieve this goal, users run a smartphone app that continually broadcasts an ephemeral, pseudo-random ID representing the user's phone and also records the pseudo-random IDs observed from smartphones in close proximity. When a patient is diagnosed with COVID-19, she can upload pseudo-random IDs previously broadcast from her phone to a central server. Prior to the upload, all data remains exclusively on the user's phone. Other users' apps can use data from the server to locally estimate whether the device's owner was exposed to the virus through close-range physical proximity to a COVID-19 positive person who has uploaded their data. In case the app detects a high risk, it will inform the user., Comment: 46 pages, 6 figures, first published 3 April 2020 on https://github.com/DP-3T/documents where companion documents and code can be found
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- 2020
114. Strangers in the Room: Unpacking Perceptions of 'Smartness' and Related Ethical Concerns in the Home
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Seymour, William, Binns, Reuben, Slovak, Petr, Van Kleek, Max, and Shadbolt, Nigel
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Computer Science - Human-Computer Interaction - Abstract
The increasingly widespread use of 'smart' devices has raised multifarious ethical concerns regarding their use in domestic spaces. Previous work examining such ethical dimensions has typically either involved empirical studies of concerns raised by specific devices and use contexts, or alternatively expounded on abstract concepts like autonomy, privacy or trust in relation to 'smart homes' in general. This paper attempts to bridge these approaches by asking what features of smart devices users consider as rendering them 'smart' and how these relate to ethical concerns. Through a multimethod investigation including surveys with smart device users (n=120) and semi-structured interviews (n=15), we identify and describe eight types of smartness and explore how they engender a variety of ethical concerns including privacy, autonomy, and disruption of the social order. We argue that this middle ground, between concerns arising from particular devices and more abstract ethical concepts, can better anticipate potential ethical concerns regarding smart devices., Comment: 10 pages, 1 figure. To appear in the Proceedings of the 2020 ACM Conference on Designing Interactive Systems (DIS '20)
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- 2020
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115. Modelling and Synchronisation of Delayed Packet-Coupled Oscillators in Industrial Wireless Sensor Networks
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Zong, Yan, Dai, Xuewu, Canyelles-Pericas, Pep, Busawon, Krishna, Binns, Richard, and Gao, Zhiwei
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Electrical Engineering and Systems Science - Systems and Control - Abstract
In this paper, a Packet-Coupled Oscillators (PkCOs) synchronisation protocol is proposed for time-sensitive Wireless Sensor Networks (WSNs) based on Pulse-Coupled Oscillators (PCO) in mathematical biology. The effects of delays on synchronisation performance are studied through mathematical modelling and analysis of packet exchange and processing delays. The delay compensation strategy (i.e., feedforward control) is utilised to cancel delays effectively. A simple scheduling function is provided with PkCOs to allocate the packet transmission event to a specified time slot, by configuring reference input of the system to a non-zero value, in order to minimise the possibility of packet collision in synchronised wireless networks. The rigorous theoretical proofs are provided to validate the convergence and stability of the proposed synchronisation scheme. Finally, the simulations and experiments examine the effectiveness of PkCOs with delay compensation and scheduling strategies. The experimental results also show that the proposed PkCOs algorithm can achieve synchronisation with the precision of $26.3\mu s$ ($1$ tick).
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- 2020
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116. Understanding changes in the timing of heavy storms: a regional case study of climate change impacts
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Jiang, Albert, McBean, Edward, Zeng, Peineng, Wang, Yi, Chen, Han, Binns, Andrew, and Gharabaghi, Bahram
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- 2023
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117. Designing and developing a mobile app (BeBo) in a randomized controlled trial study to promote breastfeeding among Vietnamese mothers
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Doan, Thi Thuy Duong, Tran, Trung Chuyen, Pham, Ngoc Minh, Zhao, Yun, Dinh, Thi Phuong Hoa, Hoai, Nguyen Xuan, Lee, Andy, Binns, Colin, and Bui, Thi Thu Ha
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- 2023
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118. “It’s all about the money”: an interpretive description of embedding physical therapy-led falls prevention group exercise in long-term care
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Binns, Elizabeth, Bright, Felicity, Parsons, John, Peri, Kathy, Taylor, Lynne, Kerse, Ngaire, and Taylor, Denise
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- 2023
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119. The impact of viral mutations on recognition by SARS-CoV-2 specific T cells
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de Silva, Thushan I, Liu, Guihai, Lindsey, Benjamin B, Dong, Danning, Moore, Shona C, Hsu, Nienyun Sharon, Shah, Dhruv, Wellington, Dannielle, Mentzer, Alexander J, Angyal, Adrienn, Brown, Rebecca, Parker, Matthew D, Ying, Zixi, Yao, Xuan, Turtle, Lance, Dunachie, Susanna, Aanensen, David M, Abudahab, Khalil, Adams, Helen, Adams, Alexander, Afifi, Safiah, Aggarwal, Dinesh, Ahmad, Shazaad SY, Aigrain, Louise, Alcolea-Medina, Adela, Alikhan, Nabil-Fareed, Allara, Elias, Amato, Roberto, Annett, Tara, Aplin, Stephen, Ariani, Cristina V, Asad, Hibo, Ash, Amy, Ashfield, Paula, Ashford, Fiona, Atkinson, Laura, Attwood, Stephen W, Auckland, Cressida, Aydin, Alp, Baker, David J, Baker, Paul, Balcazar, Carlos E, Ball, Jonathan, Barrett, Jeffrey C, Barrow, Magdalena, Barton, Edward, Bashton, Matthew, Bassett, Andrew R, Batra, Rahul, Baxter, Chris, Bayzid, Nadua, Beaver, Charlotte, Beckett, Angela H, Beckwith, Shaun M, Bedford, Luke, Beer, Robert, Beggs, Andrew, Bellis, Katherine L, Berry, Louise, Bertolusso, Beatrice, Best, Angus, Betteridge, Emma, Bibby, David, Bicknell, Kelly, Binns, Debbie, Birchley, Alec, Bird, Paul W, Bishop, Chloe, Blacow, Rachel, Blakey, Victoria, Blane, Beth, Bolt, Frances, Bonfield, James, Bonner, Stephen, Bonsall, David, Boswell, Tim, Bosworth, Andrew, Bourgeois, Yann, Boyd, Olivia, Bradley, Declan T, Breen, Cassie, Bresner, Catherine, Breuer, Judith, Bridgett, Stephen, Bronner, Iraad F, Brooks, Ellena, Broos, Alice, Brown, Julianne R, Bucca, Giselda, Buchan, Sarah L, Buck, David, Bull, Matthew, Burns, Phillipa J, Burton-Fanning, Shirelle, Byaruhanga, Timothy, Byott, Matthew, Campbell, Sharon, Carabelli, Alessandro M, Cargill, James S, and Carlile, Matthew
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Infectious Diseases ,Prevention ,Vaccine Related ,Biodefense ,Immunization ,Emerging Infectious Diseases ,Clinical Research ,Good Health and Well Being ,COVID-19 Genomics UK (COG-UK) Consortium ,ISARIC4C Investigators ,Immune response ,Immunology ,Molecular biology ,Phylogenetics ,Virology - Abstract
We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of recognition by epitope-specific T cells assessed by IFN-γ and cytotoxic killing assays. Complete loss of T cell responsiveness was seen due to Q213K in the A∗01:01-restricted CD8+ ORF3a epitope FTSDYYQLY207-215; due to P13L, P13S, and P13T in the B∗27:05-restricted CD8+ nucleocapsid epitope QRNAPRITF9-17; and due to T362I and P365S in the A∗03:01/A∗11:01-restricted CD8+ nucleocapsid epitope KTFPPTEPK361-369. CD8+ T cell lines unable to recognize variant epitopes have diverse T cell receptor repertoires. These data demonstrate the potential for T cell evasion and highlight the need for ongoing surveillance for variants capable of escaping T cell as well as humoral immunity.
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- 2021
120. Legal Taxonomies of Machine Bias: Revisiting Direct Discrimination.
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Reuben Binns, Jeremias Adams-Prassl, and Aislinn Kelly-Lyth
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- 2023
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121. 'We are adults and deserve control of our phones': Examining the risks and opportunities of a right to repair for mobile apps.
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Konrad Kollnig, Siddhartha Datta, Thomas Serban Von Davier, Max Van Kleek, Reuben Binns, Ulrik Lyngs, and Nigel Shadbolt
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- 2023
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122. 'You are you and the app. There's nobody else.': Building Worker-Designed Data Institutions within Platform Hegemony.
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Jake M. L. Stein, Vidminas Vizgirda, Max Van Kleek, Reuben Binns, Jun Zhao 0003, Rui Zhao 0009, Naman Goel, George Chalhoub, Wael S. Albayaydh, and Nigel Shadbolt
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- 2023
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123. Spectators of AI : Football Fans vs. the Semi-Automated Offside Technology at the 2022 FIFA World Cup.
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Sruthi Viswanathan, Ravi Shankar, Jack Jackson, and Reuben Binns
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- 2023
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124. Music and Comedy in the Films of Woody Allen
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Binns, Alexander, Audissino, Emilio, editor, and Wennekes, Emile, editor
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- 2023
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125. Parody, Comedy, Subversion: Music in Japanese Comedy Cinema
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Binns, Alexander, Audissino, Emilio, editor, and Wennekes, Emile, editor
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- 2023
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126. Effects of an Exercise Program to Reduce Falls in Older People Living in Long-Term Care: A Randomized Controlled Trial
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Taylor, Lynne M., Parsons, John, Moyes, Simon A., Binns, Elizabeth, Cavadino, Alana, Taylor, Denise, Lord, Sue, Del Din, Silvia, Klenk, Jochen, Rochester, Lynn, and Kerse, Ngaire
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- 2024
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127. The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement
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Miller, Marissa A., Taddei-Peters, Wendy C., Jeffries, Neal O., Buxton, Dennis, Geller, Nancy L., Gordon, David, Burke, Catherine, Lee, Albert, Smith, Tyrone, Moy, Claudia S., Gombos, Ilana Kogan, Weisel, Richard, Gardner, Timothy J., O'Gara, Patrick T., Rose, Eric A., Gelijns, Annetine C., Parides, Michael K., Ascheim, Deborah D., Moskowitz, Alan J., Bagiella, Emilia, Moquete, Ellen, Shah, Kinjal, Overbey, Jessica R., Pan, Stephanie, Chang, Helena, Chase, Melissa, Goldfarb, Seth, Gupta, Lopa, Kirkwood, Katherine, Dobrev, Edlira, Levitan, Ron, O'Sullivan, Karen, Santos, Milerva, Ye, Xia, Mack, Michael, Winkle, Rachelle, Boswell, Haley, Fenlon, Amanda, Johnson, Melissa, Jones, Jessica, Kolb, Megan, Lam, Sarah, Miranda, Lucy, Ward, Jackie, Whitman, Renessa, Zingler, Brittany, Ryan, William, Smith, Robert L., Grayburn, Paul, Nosnik, Pedro, Gillinov, A. Marc, Blackstone, Eugene H., Moazami, Nader, Starling, Randall C., Barzilai, Benico, Grimm, Richard A., Soltesz, Edward G., Katzan, Irene, Strippy, Brian, Smith, Shoi, Garcia, Michelle, Alice bowman, Mary, Geither, Carrie, Wang, Robert, Argenziano, Michael, Borger, Michael, Takayama, Hiroo, Leon, Martin B., Goldsmith, Lyn, Schwartz, Allan, Sookraj, Nadia, McCright-Gill, Talaya, Sreekanth, Sowmya, McCullough, Jock N., Iribarne, Alexander, DeSimone, Joseph P., DiScipio, Anthony W., Stokes, Henry, Ivany, Amanda St., Petty, Gaylin, Smith, Peter K., Alexander, John H., Milano, Carmelo A., Glower, Donald D., Huber, Joel, Morganlander, Joel, Mathew, Joseph P., Welsh, Stacey, Casalinova, Sarah, Johnson, Victoria, Lane, Kathleen, Smith, Derek, Tipton, Greg, Berry, Mark F., Williams, Judson B., Englum, Brian, Hartwig, Matthew, Thourani, Vinod H., Guyton, Robert, Lattouf, Omar, Chen, Edward, Vega, J. David, Baer, Jefferson, Nguyen, Duc, Halkos, Michael, Baio, Kim, Prince, Tamara, Cook, Natascha, Neill, Alexis A., Voisine, Pierre, Senechal, Mario, Dagenais, François, Laforce, Robert, Jr., O'Connor, Kim, Dussault, Gladys, Caouette, Manon, Tremblay, Hugo, Gagne, Nathalie, Dumont, Julie, Landry, Patricia, Groh, Mark A., Trichon, Benjamin H., Binns, Oliver A., Ely, Stephen W., Johnson, Alan M., Hansen, Todd H., Short, John G., Taylor, Reid D., Mangusan, Ralph, Nanney, Tracy, Aubart, Holly, Cross, Kristin, McPeters, Leslie, Riggsbee, Christina, Rixey, Lucy, Michler, Robert E., DeRose, Joseph J., Jr., Goldstein, Daniel J., Bello, Ricardo A., Taub, Cynthia, Spevack, Daniel, Kirchoff, Kathryn, Meli, Rebecca, Garcia, Juan, Goldenberg, Jon, Kealy, Lauren, Perrault, Louis P., Bouchard, Denis, Tanguay, Jean François, O'Meara, Eileen, Lacharité, Jonathan, Robichaud, Sophie, Horvath, Keith A., Corcoran, Philip C., Siegenthaler, Michael P., Murphy, Mandy, Iraola, Margaret, Greenberg, Ann, Kumkumian, Greg, Milner, Mark, Nadareishvili, Zurab, Whitson, Bryan A., Hasan, Ayesha, McDavid, Asia, Fadorsen, Denise, Ouzounian, Maral, Yau, Terry, Farkouh, Michael, Woo, Anna, Cusimano, Robert James, David, Tirone, Feindel, Christopher, Fumakia, Nishit, Christie, Shakira, Mullen, John C., Bissonauth, Asvina, Hripko, Alexandra, Gammie, James S., Noor, Zahid, Mackowick, Kristen, Deasey, Stephanie, Al-Suqi, Manal, Collins, Julia, Acker, Michael A., Messé, Steven, Kirkpatrick, James, Mayer, Mary Lou, McDonald, Caitlin, Fok, Holley, Maffei, Breanna, Cresse, Stephen, Gepty, Christine, Bowdish, Michael, Starnes, Vaughn A., Shavalle, David, Heck, Christi, Hackmann, Amy, Baker, Craig, Fleischman, Fernando, Cunningham, Mark, Lozano, Edward, Hernandez, Michelle, Ailawadi, Gorav, Kron, Irving L., Johnston, Karen, Ghanta, Ravi K., Dent, John M., Kern, John, Yarboro, Leora, Ragosta, Michael, Annex, Brian, Bergin, Jim, Burks, Sandra, Cosner, Mike, Green, China, Loya, Samantha, Kim, Hye Ryun, Bull, David A., Desvigne-Nickens, Patrice, Dixon, Dennis O., Gottesman, Rebecca, Haigney, Mark, Holubkov, Richard, Iadecola, Constantino, Jacobs, Alice, Meslin, Eric M., Murkin, John M., Spertus, John A., Sellke, Frank, McDonald, Cheryl L., Canty, John, Dickert, Neal, Ikonomidis, John S., Kim, KyungMann, Williams, David O., Yancy, Clyde W., Chaturvedi, Seemant, Chimowitz, Marc, Fang, James C., Richenbacher, Wayne, Rao, Vivek, Furie, Karen L., Miller, Rachel, Cook, Jennifer, D'Alessandro, David, Han, Frederick, Pinney, Sean, Walsh, Mary N., Greer, David, Ishida, Koto, Stapf, Christian, Hung, Judy, Zeng, Xin, Hung, David, Satitthummanid, Sudarat, Billelo, Michel, Davatzikos, Christos, Erus, Guray, Karpf, Lauren, Desiderio, Lisa, Browndyke, Jeffrey N., James, Michael L., Toulgoat-Dubois, Yanne, Brassard, Rachele, Virmanu, Renu, Romero, Maria E., Braumann, Ryan, Messé, Steven R., Mack, Michael J., Southerland, Andrew M., Moy, Claudia Scala, and Bowdish, Michael E.
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- 2024
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128. Acoustofluidic patterning in glass capillaries using travelling acoustic waves based on thin film flexible platform
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Wang, Qiaoyun, Maramizonouz, Sadaf, Stringer Martin, Mercedes, Zhang, Jikai, Ong, Hui Ling, Liu, Qiang, Yang, Xin, Rahmati, Mohammad, Torun, Hamdi, Ng, Wai Pang, Wu, Qiang, Binns, Richard, and Fu, Yongqing
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- 2024
- Full Text
- View/download PDF
129. Reputation Management in the ChatGPT Era.
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Lilian Edwards and Reuben Binns
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- 2024
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130. The Interaction Layer: An Exploration for Co-Designing User-LLM Interactions in Parental Wellbeing Support Systems.
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Sruthi Viswanathan, Seray B. Ibrahim, Ravi Shankar, Reuben Binns, Max Van Kleek, and Petr Slovák
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- 2024
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131. "Diversity is Having the Diversity": Unpacking and Designing for Diversity in Applicant Selection.
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Neil Natarajan, Sruthi Viswanathan, Reuben Binns, and Nigel Shadbolt
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- 2024
- Full Text
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132. Unlawful Proxy Discrimination: A Framework for Challenging Inherently Discriminatory Algorithms.
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Hilde J. P. Weerts, Aislinn Kelly-Lyth, Reuben Binns, and Jeremias Adams-Prassl
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- 2024
- Full Text
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133. Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
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Abani, O, Abbas, A, Abbas, F, Abbas, J, Abbas, K, Abbas, M, Abbasi, S, Abbass, H, Abbott, A, Abdallah, N, Abdelaziz, A, Abdelfattah, M, Abdelqader, B, Abdul, A, Abdul, B, Abdul, S, Abdul Rasheed, A, Abdulakeem, A, Abdul-Kadir, R, Abdullah, A, Abdulmumeen, A, Abdul-Raheem, R, Abdulshukkoor, N, Abdusamad, K, Abed El Khaleq, Y, Abedalla, M, Abeer Ul Amna, A, Abel, L, Abernethy, K, Abeywickrema, M, Abhinaya, C, Abidin, A, Aboaba, A, Aboagye-Odei, A, Aboah, C, Aboelela, H, Abo-Leyah, H, Abouelela, K, Abou-Haggar, A, Abouibrahim, M, Abousamra, A, Abouzaid, M, Abraham, M, Abraham, T, Abraheem, A, Abrams, J, Abrams, R, Abu, HJ, Abu-Arafeh, A, Abubacker, SM, Abung, A, Abusamra, Y, Aceampong, Y, Achara, A, Acharya, D, Acheampong, F, Acheampong, P, Acheampong, S, Acheson, J, Achieng, S, Acosta, A, Acquah, R, Acton, C, Adabie-Ankrah, J, Adair, P, Adam, AS, Adam, F, Adam, M, Adamali, H, Adamczyk, M, Adams, C, Adams, D, Adams, K, Adams, L, Adams, N, Adams, R, Adams, T, Adamu-Ikeme, L, Adatia, K, Adcock, K, Addai-Boampong, L, Addo, A, Adeagbo, O, Adebiyi, A, Adedeji, O, Adegeye, Y, Adegoke, K, Adell, V, Adenwalla, S, Adeoye, FW, Adesemoye, OA, Adewunmi, EO, Adeyanju, A, Adeyemi, J, Adeyemo, T, Adhikari, B, Adhikari, SA, Adhikary, R, Aditya, A, Adjepong, P, Adkins, G, Adnan, A, Adriaanse, M, Aeron-Thomas, J, Affleck, D, Afnan, C, Afridi, M, Afrim, P, Afriyie, FA, Aftab, ZA, Afum-Adjei Awuah, A, Agarwal, M, Agasiya, PN, Agbeko, R, Agbo, C, Aggarwal, S, Aghababaie, A, Aguilar Jimenez, L, Agyekum, JA, Agyen, K, Ahadome, EK, Ahamed Sadiq, S, Ahammed Nazeer, MH, Ahmad, M, Ahmad, S, Ahmed, A, Ahmed, BAR, Ahmed, B, Ahmed, F, Ahmed, H, Ahmed, I, Ahmed, K, Ahmed, L, Ahmed, M, Ahmed, MC, Ahmed, MS, Ahmed, N, Ahmed, O, Ahmed, RA, Ahmed, R, Ahmed, S, Ahmed, SG, Ahmed, SH, Ahmed Ali, R, Ahmed Mohamud, B, Ahmer, S, Ahonia, A, Aidoo, C, Aiken, C, Ail, D, Ainsworth, M, Aissa, M, Aitken, L, Ajay, B, Ajibode, A, Ajmi, A, Akhtar, N, Akili, S, Akinbiyi, B, Akindolie, O, Akinfenwa, Y, Akinkugbe, O, Akinpelu, I, Akram, M, Aktinade, O, Akudi, U, Al Aaraj, ASAR, Al Balushi, A, Al Dakhola, M, Al Swaifi, A, Al-Abadi, E, Alabi, A, Aladangady, N, Alafifi, M, Alam, A, Alam, S, Al-Asadi, A, Alatzoglou, K, Albert, P, Albertus, A, Albon, L, Alcala, A, Alcorn, G, Alcorn, S, Aldana, A, Alderdice, D, Aldesouki, A, Aldouri, R, Aldridge, J, Aldridge, N, Ale, RM, Alegria, A, Alexander, A, Alexander, C, Alexander, J, Alexander, PDG, Al-fori, J, Alghazawi, L, Alhabsha, O, Al-Hakim, B, Alhameed, R, Al-Hayali, M, Al-Hity, S, Ali, A, Ali, FR, Ali, J, Ali, M, Ali, MS, Ali, N, Ali, O, Ali, R, Ali, S, Aliberti, E, Alin, J, Alina, A, Alipustain, A, Alisjahbana, B, Aliyuda, F, Alizadeh, K, Al-Jibury, M, Al-Juboori, S, Al-Khalil, M, Alkhudhayri, A, Alkhusheh, M, Allan, F, Allan, N, Allanson, A, Allcock, R, Allen, E, Allen, J, Allen, K, Allen, L, Allen, P, Allen, R, Allen, S, Allen, T, Alli, A, Allison, K, Allman, B, Allsop, HK, Allsop, L, Allsup, D, Almahroos, AFT, Al-Moasseb, H, Al-Obaidi, M, Alomari, L, Al-Rabahi, A, Al-Ramadhani, B, Al-Saadi, Z, Al-Sammarraie, R, Alshaer, I, Al-Shahi Salman, R, Al-Shamkhani, W, Alsheikh, F, Al-Sheklly, B, Altaf, S, Alty, A, Alvarez, M, Alvarez Corral, M, Alveyn, E, Alzetani, M, Amamou, S, Amar, N, Ambalavanan, S, Ambrogetti, R, Ambrose, C, Ameen, A, Amelia Ganefianty, A, Ames, K, Amezaga, MR, Amin, A, Amin, K, Amin, S, Amin, T, Amit, B, Amjad, A, Amjad, N, Amoah-Dankwa, J, Amoako-Adusei, A, Amosun, V, Amsal, M, Amsha, K, Amuasi, J, Amutio Martin, N, Amy, P, Anada, A, Anand, A, Anandappa, S, Anantapatnaikuni, SD, Andari, NKN, Anderson, E, Anderson, J, Anderson, L, Anderson, M, Anderson, N, Anderson, R, Anderson, S, Anderson, W, Andreou, P, Andrews, A, Andrews, J, Aneke, K, Ang, A, Ang, WW, Angel, T, Angela, A, Angelini, P, Anguvaa, L, Anichtchik, O, Anim-Somuah, M, Aniruddhan, K, Annett, J, Anning, L, Ansah, M, Anstey, PJ, Anstey, R, Anthony, A, Anthony-Pillai, A, Antill, P, Antonina, Z, Anu, V, Anwar, M, Anwar, S, Apetri, E, Apostolopoulos, A, Appleby, S, Appleyard, D, Aquino, MF, Araba, B, Aransiola, S, Araujo, M, Archer, A, Archer, D, Archer, S, Arcoria, D, Ardley, C, Arhin-Sam, G, Arias, A-M, Aribike, O, Arimoto, R, Arisanti, NLPE, Arkley, C, Armah, C, Armata, I, Armistead, J, Armitage, A, Armstrong, C, Armstrong, M, Armstrong, S, Armstrong, W, Armtrong, P, Arndt, H, Arnison-Newgass, C, Arnold, D, Arnold, R, Arnott, A, Arora, D, Arora, K, Arora, P, Arora, R, Arter, A, Arthur, A, Artini, NM, Arumaithurai, A, Arya, A, Arya, R, Aryal, D, Asandei, D, Asare, GA, Asghar, A, Asghar, M, Ashab, A, Ashbrook-Raby, C, Ashby, H, Ashcroft, J, Ashcroft, S, Asher, G, Ashfak, Z, Ashfaq, A, Asiamah, HA, Ashish, A, Ashley, D, Ashman-Flavell, S, Ashok, S, Ashour, A-E-A, Ashraf, MZ, Ashraf, S, Ashraq, MB, Ashton, D, Ashton, S, Ashworth, A, Ashworth, FJ, Ashworth, R, Aslam, A, Aslam, I, Aslam, S, Aslett, L, Asogan, H, Asrar, A, Assaf, O, Astin-Chamberlain, R, Atabudzi, YE, Athavale, P, Athorne, D, Atkins, B, Atkins, C, Atkins, S, Atkinson, J, Atkinson, V, Atomode, A, Atraskiewicz, B, Attia, AA, Attubato, E, Attwood, M, Aubrey, P, Auer, Z, Aujayeb, A, Aung, AT, Aung, H, Aung, HWW, Aung, KK, Aung, KT, Aung, N, Aung, Y, Aung, ZM, Austin, E, Austin, K, Auwal, A, Avari, M, Avery, M, Aveyard, N, Avis, J, Aviss, G, Avram, C, Avram, P, Awadelkareem, A, Awadzi, G, Awaly, M, Awan, A, Awisi, S, Aya, A, Ayaz, E, Ayerh, JM, Ayers, A, Azam, J, Azeem, A, Azharuddin, M, Aziz, A, Aziz, G, Aziz, I, Aziz, N, Azkoul, A, Azman Shah, A, Azzopardi, G, Azzoug, H, Babatunde, F, Babi, M, Babiker, B, Babington, G, Babirecki, M, Babores, M, Babs-Osibodu, AO, Bac, T, Bacciarelli, S, Bachar, R, Bachour, M-E, Bachti, A, Bacon, G, Bacon, J, Badal, B, Badat, A, Bader, M, Badhan, GR, Badhrinarayanan, S, Bae, JP, Baggaley, A, Baggott, A, Bagley, G, Bagmane, D, Bagshaw, L, Bahadori, K, Bahurupi, Y, Bailey, A, Bailey, J, Bailey, K, Bailey, L, Bailey, MA, Bailey, M, Bailey, P, Bailey, S, Baillie, H, Baillie, JK, Bain, J, Bains, V, Baird, D, Baird, E, Baird, K, 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- 2023
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134. Exploring the Empirical Connection between Student, Teacher, School, and District-Level Variables on Fifth Grade Students' Mathematics Achievement
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Polly, Drew, Wang, Chaung, Petty, Teresa, and Binns, Ian
- Abstract
This study used hierarchical linear modeling (HLM) to examine the relationship of student, teacher, school, and district-level variables on students' mathematics achievement as measured on the Grade 5 end of year assessment in North Carolina. Analyses indicated that there were statistically significant relationships between gains in student achievement and students' gender and ethnicity, teachers' advanced degrees (e.g., Master's and Doctorate), teachers' years of experience, and National Board Certification status. In terms of school and district-level variables, there were statistically significant relationships between students' mathematics achievement and the district's teachers' ratings of their job satisfaction as well as the district's percentages of teachers who had either graduate degrees and National Board Certification. Future research should examine the influence of these variables on mathematics achievement in other populations as well as tease out specific instructional practices in classrooms that may contribute to gains in student outcomes.
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- 2022
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135. WNK1 collaborates with TGF-β in endothelial cell junction turnover and angiogenesis
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Jaykumar, Ankita B., Plumber, Sakina, Barry, David M., Binns, Derk, Wichaidit, Chonlarat, Grzemska, Magdalena, Earnest, Svetlana, Goldsmith, Elizabeth J., Cleaver, Ondine, and Cobb, Melanie H.
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- 2022
136. The treatment of elderly patients with locally advanced or metastatic cutaneous squamous cell carcinoma using Cemiplimab monotherapy or Cemiplimab associated with palliative radiotherapy: A single centre experience from the United Kingdom
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A. del Carpio Barreda, A. Mcmillan, V. Bansal, C. Binns, and P. Matteucci
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2024
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137. P565: Exploring genetic testing for rare disorders of obesity: Experience and perspectives of pediatric weight management providers
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Karyn Roberts, Eileen Chaves, Adolfo Ariza, Vidhu Thaker, Chi Cho, and Helen Binns
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Genetics ,QH426-470 ,Medicine - Published
- 2024
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138. Age and sex-related variations in murine laryngeal microbiota
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Ran An, Anumitha Venkatraman, John Binns, Callie Saric, Federico E. Rey, and Susan L. Thibeault
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Medicine ,Science - Published
- 2024
139. Associations between MRI-visible perivascular spaces, brain atrophy, white matter hyperintensities, and speeded executive function, in neurodegenerative and cerebrovascular diseases.
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Daniela Andriuta, Joel Ramirez, Fuqiang Gao, Jennifer Rabin, Madeline E Wood, Paula M McLaughlin, Christopher JM Scott, Miracle Ozzoude, Allison A Dilliott, Robert A Hegele, Maria C Tartaglia, David Tang-Wai, Richard H Swartz, Leanne Casaubon, Sanjeev Kumar, Dar Dowlatshahi, Jennifer Mandzia, Demetrios Sahlas, Gustavo Saposnik, Corinne Fischer, Michael Borrie, Ayman Hassan, Malcolm A Binns, Morris Freedman, Elizabeth Finger, Andrew Frank, Robert Bartha, Sean Symons, Mario Masellis, and Sandra E Black
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Specialties of internal medicine ,RC581-951 ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Introduction: MRI-visible perivascular spaces (PVS) are a neuroimaging feature of cerebral small vessel disease and are commonly observed in patients with cerebrovascular and neurodegenerative disease. However, it is unclear whether PVS burden is associated with cognition. The aim of this study was to investigate the potential associations between PVS volumes, brain atrophy, white matter hyperintensities (WMH), and speeded executive function, in patients from the Ontario Neurodegenerative Disease Research Initiative (ONDRI). Methods: ONDRI participants (n=333) clinically diagnosed with Alzheimer's disease/mild cognitive impairment (ADMCI), frontotemporal dementia (FTD), and cerebrovascular diseases (CVD), with clinical, neuropsychological, MRI, plasma biomarkers (glial fibrillary acidic protein (GFAP); neurofilament light, (NfL); p-tau181; Aβ42/40), and available apolipoprotein E epsilon 4 (APOE E4) status, were included in this analysis. MRI-based measurements for brain parenchymal fraction (BPF), lacunes, PVS and WMH were extracted using the ONDRI imaging pipeline. The neuropsychological test scores were standardized (z-transformed), speeded executive function z- scores were computed as the mean of digit symbol modalities test and trail making test part B timed z-scores. The variables selected in bivariate analysis (p
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- 2024
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140. Examining perivascular spaces (PVS) in cerebral small vessel disease (CSVD) using a novel T1- based automated PVS segmentation tool
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Erin Gibson, Joel Ramirez, Lauren A. Woods, Rosa Sommers, Nasim M. Ghahjaverestan, Christopher J.M. Scott, Fuqiang Gao, Anthony E. Lang, Connie Marras, David P. Breen, Maria C. Tartaglia, Malcolm A. Binns, Robert Bartha, Sean Symons, Richard H. Swartz, Mario Masellis, Sandra E. Black, Alan Moody, Andrew SP Lim, and Maged Goubran
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Specialties of internal medicine ,RC581-951 ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Introduction: White matter hyperintensities (WMH) and MRI-visible perivascular spaces (PVS) are neuroimaging features of cerebral small vessel disease (CSVD). PVS are believed to play a role in cerebral metabolic waste clearance, particularly during sleep, and emerging evidence suggests that sleep disturbances are among the earliest symptoms of dementia. However, PVS quantification remains challenging and not accessible, particularly in complex patients with neurovascular and neurodegenerative disease. We developed and validated an automated deep learning-based PVS quantification method using multi-site patient MRI with varying degrees of CSVD burden. Additionally, we examined the correlation between PVS volumes and age in patients undergoing treatment for sleep apnea. Methods: MRI (training/validation data=141; testing=15) were obtained from various multi-site studies (ONDRI, CAHHM, Leducq SVD-PVS, CAIN). We developed a deep learning convolutional neural net (CNN) model with a U-net architecture for PVS segmentation using T1-weighted images. Ground truth data used for model training were generated by first applying the RORPO filter to extract small tubular structures, then refinement of the RORPO output around WMH, followed by removal of probable non-PVS objects from the RORPO-based output using Freesurfer regions of interest, and finally manually correcting the remaining errors. After ground truth generation and model training, the final CNN output was used to examine the association between PVS volumes and age in patients with sleep apnea (n=42). Results: After CNN training, our PVS tool completes full segmentation in under 3 minutes (NVIDIA RTX3090). It achieved excellent performance on the test data, with a mean Dice score of 0.95, indicating outstanding agreement with ground truth. When applied to the patients undergoing interventional sleep apnea treatment, a strong positive relationship was found between total PVS volume and age (r=0.57 [0.38 0.72]). Discussion: Our findings suggest that our automated PVS segmentation method can quickly and accurately quantify PVS in neurodegenerative and neurovascular patients with varying degrees of CSVD burden. The strong association between age and PVS in patients with sleep apnea further demonstrates the utility of our method and underscores the importance of further investigating the role of PVS in the context of sleep, aging, and neurodegenerative processes.
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- 2024
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141. Informing the Design of Privacy-Empowering Tools for the Connected Home
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Seymour, William, Kraemer, Martin J., Binns, Reuben, and Van Kleek, Max
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Computer Science - Human-Computer Interaction - Abstract
Connected devices in the home represent a potentially grave new privacy threat due to their unfettered access to the most personal spaces in people's lives. Prior work has shown that despite concerns about such devices, people often lack sufficient awareness, understanding, or means of taking effective action. To explore the potential for new tools that support such needs directly we developed Aretha, a privacy assistant technology probe that combines a network disaggregator, personal tutor, and firewall, to empower end-users with both the knowledge and mechanisms to control disclosures from their homes. We deployed Aretha in three households over six weeks, with the aim of understanding how this combination of capabilities might enable users to gain awareness of data disclosures by their devices, form educated privacy preferences, and to block unwanted data flows. The probe, with its novel affordances-and its limitations-prompted users to co-adapt, finding new control mechanisms and suggesting new approaches to address the challenge of regaining privacy in the connected home., Comment: 10 pages, 2 figures. To appear in the Proceedings of the 2020 CHI Conference on Human Factors in Computing Systems (CHI '20)
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- 2020
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142. Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids
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Han, Qi, Su, Yuyu, Smith, Kate M., Binns, Jack, Drummond, Calum J., Darmanin, Connie, and Greaves, Tamar L.
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- 2023
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143. Application of classification machine learning algorithms for characterizing nutrient transport in a clay plain agricultural watershed
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Elsayed, Ahmed, Rixon, Sarah, Levison, Jana, Binns, Andrew, and Goel, Pradeep
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- 2023
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144. Facing post-crisis livelihood challenges? Insights from young farmers in Kenema city, Eastern Province, Sierra Leone
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Bangura, Kabba. S., Lynch, Kenneth, Binns, Tony, and Gbanie, Solomon
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- 2023
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145. Text mining-aided meta-research on nutrient dynamics in surface water and groundwater: Popular topics and perceived gaps
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Elsayed, Ahmed, Rixon, Sarah, Zeuner, Christina, Levison, Jana, Binns, Andrew, and Goel, Pradeep
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- 2023
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146. Mechanical properties and pore network connectivity of sodium montmorillonite as predicted by a coarse-grained molecular model
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Zhang, Yaoting, Opletal, George, Briggs, Scott, Binns, W. Jeffrey, and Béland, Laurent Karim
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- 2023
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147. On the Apparent Conflict Between Individual and Group Fairness
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Binns, Reuben
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Computer Science - Machine Learning ,Computer Science - Computers and Society ,Statistics - Machine Learning - Abstract
A distinction has been drawn in fair machine learning research between `group' and `individual' fairness measures. Many technical research papers assume that both are important, but conflicting, and propose ways to minimise the trade-offs between these measures. This paper argues that this apparent conflict is based on a misconception. It draws on theoretical discussions from within the fair machine learning research, and from political and legal philosophy, to argue that individual and group fairness are not fundamentally in conflict. First, it outlines accounts of egalitarian fairness which encompass plausible motivations for both group and individual fairness, thereby suggesting that there need be no conflict in principle. Second, it considers the concept of individual justice, from legal philosophy and jurisprudence which seems similar but actually contradicts the notion of individual fairness as proposed in the fair machine learning literature. The conclusion is that the apparent conflict between individual and group fairness is more of an artifact of the blunt application of fairness measures, rather than a matter of conflicting principles. In practice, this conflict may be resolved by a nuanced consideration of the sources of `unfairness' in a particular deployment context, and the carefully justified application of measures to mitigate it., Comment: Conference on Fairness, Accountability, and Transparency (FAT* '20), January 27--30, 2020, Barcelona, Spain
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- 2019
148. Informing The Future of Data Protection in Smart Homes
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Kraemer, Martin J, Seymour, William, Binns, Reuben, Van Kleek, Max, and Flechais, Ivan
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Computer Science - Human-Computer Interaction - Abstract
Recent changes to data protection regulation, particularly in Europe, are changing the design landscape for smart devices, requiring new design techniques to ensure that devices are able to adequately protect users' data. A particularly interesting space in which to explore and address these challenges is the smart home, which presents a multitude of difficult social and technical problems in an intimate and highly private context. This position paper outlines the motivation and research approach of a new project aiming to inform the future of data protection by design and by default in smart homes through a combination of ethnography and speculative design., Comment: Proceedings of the CHI 2019 Workshop on New Directions for the IoT: Automate, Share, Build, and Care, (arXiv:1906.06089)
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- 2019
149. Direct Measurement of the Cosmic-Ray Proton Spectrum from 50 GeV to 10 TeV with the Calorimetric Electron Telescope on the International Space Station
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Adriani, O., Akaike, Y., Asano, K., Asaoka, Y., Bagliesi, M. G., Berti, E., Bigongiari, G., Binns, W. R., Bonechi, S., Bongi, M., Bruno, A., Buckley, J. H., Cannady, N., Castellini, G., Checchia, C., Cherry, M. L., Collazuol, G., Di Felice, V., Ebisawa, K., Fuke, H., Guzik, T. G., Hams, T., Hasebe, N., Hibino, K., Ichimura, M., Ioka, K., Ishizaki, W., Israel, M. H., Kasahara, K., Kataoka, J., Kataoka, R., Katayose, Y., Kato, C., Kawanaka, N., Kawakubo, Y., Kohri, K., Krawczynski, H. S., Krizmanic, J. F., Lomtadze, T., Maestro, P., Marrocchesi, P. S., Messineo, A. M., Mitchell, J. W., Miyake, S., Moiseev, A. A., Mori, K., Mori, M., Mori, N., Motz, H. M., Munakata, K., Murakami, H., Nakahira, S., Nishimura, J., de Nolfo, G. A., Okuno, S., Ormes, J. F., Ozawa, S., Pacini, L., Palma, F., Papini, P., Penacchioni, A. V., Rauch, B. F., Ricciarini, S. B., Sakai, K., Sakamoto, T., Sasaki, M., Shimizu, Y., Shiomi, A., Sparvoli, R., Spillantini, P., Stolzi, F., Suh, J. E., Sulaj, A., Takahashi, I., Takayanagi, M., Takita, M., Tamura, T., Terasawa, T., Tomida, H., Torii, S., Tsunesada, Y., Uchihori, Y., Ueno, S., Vannuccini, E., Wefel, J. P., Yamaoka, K., Yanagita, S., Yoshida, A., and Yoshida, K.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
In this paper, we present the analysis and results of a direct measurement of the cosmic-ray proton spectrum with the CALET instrument onboard the International Space Station, including the detailed assessment of systematic uncertainties. The observation period used in this analysis is from October 13, 2015 to August 31, 2018 (1054 days). We have achieved the very wide energy range necessary to carry out measurements of the spectrum from 50 GeV to 10 TeV covering, for the first time in space, with a single instrument the whole energy interval previously investigated in most cases in separate subranges by magnetic spectrometers (BESS-TeV, PAMELA, and AMS-02) and calorimetric instruments (ATIC, CREAM, and NUCLEON). The observed spectrum is consistent with AMS-02 but extends to nearly an order of magnitude higher energy, showing a very smooth transition of the power-law spectral index from -2.81 +- 0.03 (50--500 GeV) neglecting solar modulation effects (or -2.87 +- 0.06 including solar modulation effects in the lower energy region) to -2.56 +- 0.04 (1--10 TeV), thereby confirming the existence of spectral hardening and providing evidence of a deviation from a single power law by more than 3 sigma., Comment: main text: 8 pages, 5 figures, supplemental material: 12 pages, 7 figures, 1 table, marked as a PRL Editor's Suggestion
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- 2019
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150. Ultra-heavy cosmic-ray science--Are r-process nuclei in the cosmic rays produced in supernovae or binary neutron star mergers?
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Binns, W. R., Israel, M. H., Rauch, B. F., Cummings, A. C., Davis, A. J., Labrador, A. W., Leske, R. A., Mewaldt, R. A, Stone, E. C., Wiedenbeck, M. E., Brandt, T. J., Christian, E. R., Link, J. T., Mitchell, J. W., de Nolfo, G. A., von Rosenvinge, T. T., Sakai, K., Sasaki, M., Waddington, C. J., Janka, H. T., Melott, A. L., Mason, G. M., Seo, E-S., Adams, J. H., Thielemann, F-K., Heger, A., Lugaro, M., and Westphal, A. J.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The recent detection of 60Fe in the cosmic rays provides conclusive evidence that there is a recently synthesized component (few MY) in the GCRs (Binns et al. 2016). In addition, these nuclei must have been synthesized and accelerated in supernovae near the solar system, probably in the Sco-Cen OB association subgroups, which are about 100 pc distant from the Sun. Recent theoretical work on the production of r-process nuclei appears to indicate that it is difficult for SNe to produce the solar system abundances relative to iron of r-process elements with high atomic number (Z), including the actinides (Th, U, Np, Pu, and Cm). Instead, it is believed by many that the heaviest r-process nuclei, or perhaps even all r-process nuclei, are produced in binary neutron star mergers. Since we now know that there is at least a component of the GCRs that has been recently synthesized and accelerated, models of r-process production by SNe and BNSM can be tested by measuring the relative abundances of these ultra-heavy r-process nuclei, and especially the actinides, since they are radioactive and provide clocks that give the time interval from nucleosynthesis to detection at Earth. Since BNSM are believed to be much less frequent in our galaxy than SNe (roughly 1000 times less frequent, the ratios of the actinides, each with their own half-life, will enable a clear determination of whether the heaviest r-process nuclei are synthesized in SNe or in BNSM. In addition, the r-process nuclei for the charge range from 34 to 82 can be used to constrain models of r-process production in BNSM and SNe. Thus, GCRs become a multi-messenger component in the study of BNSM and SNe., Comment: Astro2020 Science White Paper
- Published
- 2019
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