101. Assessing health-related quality of life in patients with migraine.
- Author
-
Becker WJ
- Subjects
- Humans, Patients statistics & numerical data, Health Surveys, Migraine Disorders psychology, Patients psychology, Quality of Life psychology
- Abstract
Background: The place of health-related quality of life (HRQoL) instruments in clinical research trials and clinical practice as compared to more traditional clinical outcome measures such as headache intensity and frequency is unclear., Objectives: To review the current status of HRQoL measurement in migraine., Methods: A literature search was done for HRQoL and migraine. Selected articles dealing with migraine and commonly used HRQoL instruments and HRQoL measures used in recent clinical trials were reviewed., Results: Several general and migraine specific HRQoL instruments can detect changes over time in response to at least major changes in migraine therapy. Both also show a correlation with clinical headache features. However, their sensitivity to detect clinically significant changes over time is not clear., Conclusion: The SF-36, a general HRQoL measure and several migraine-specific HRQoL instruments are useful endpoints for migraine clinical trials. Their role in clinical practice is yet to be established.
- Published
- 2002
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