Search

Your search keyword '"Bauer, Axel"' showing total 1,122 results
Start Over Author "Bauer, Axel"
1,122 results on '"Bauer, Axel"'

103. Visualization of the SyncAV ® Algorithm for CRT Optimization by Non-invasive Imaging of Cardiac Electrophysiology: NICE-CRT Trial.

Author

Spitaler, Philipp, Pfeifer, Bernhard Erich, Mayr, Agnes, Bachler, Rudolf, Bilgeri, Valentin, Adukauskaite, Agne, Bauer, Axel, Stühlinger, Markus, Barbieri, Fabian, and Dichtl, Wolfgang

Subjects
BUNDLE-branch block, CARDIAC imaging, ELECTROPHYSIOLOGY, HEART assist devices, HEART beat, HEART failure patients, CARDIAC pacing
Abstract

(1) Background: Periodic repetitive AV interval optimization using a device-based algorithm in cardiac resynchronization therapy (CRT) devices may improve clinical outcomes. There is an unmet need to successfully transform its application into clinical routine. (2) Methods: Non-invasive imaging of cardiac electrophysiology was performed in different device programming settings of the SyncAV® algorithm in 14 heart failure patients with left bundle branch block and a PR interval ≤ 250 milliseconds to determine the shortest ventricular activation time. (3) Results: the best offset time (to be manually programmed) permitting automatic dynamic adjustment of the paced atrioventricular interval after every 256 heart beats was found to be 30 and 50 milliseconds, decreasing mean native QRS duration from 181.6 ± 23.9 milliseconds to 130.7 ± 10.0 and 130.1 ± 10.5 milliseconds, respectively (p = 0.01); this was followed by an offset of 40 milliseconds (decreasing QRS duration to 130.1 ± 12.2 milliseconds; p = 0.08). (4) Conclusions: The herein presented NICE-CRT study supports the current recommendation to program an offset of 50 milliseconds as default in patients with left bundle branch block and preserved atrioventricular conduction after implantation of a CRT device capable of SyncAV® optimization. Alternatively, offset programming of 30 milliseconds may also be applied as default programming. In patients with no or poor CRT response, additional efforts should be spent to individualize best offset programming with electrocardiographic optimization techniques. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

114. Periodic Repolarization Dynamics Identifies ICD-responders in Non-ischemic Cardiomyopathy:A DANISH Substudy

Author

Boas, Rune, Sappler, Nikolay, von Stülpnagel, Lukas, Klemm, Mathias, Dixen, Ulrik, Thune, Jens Jakob, Pehrson, Steen, Køber, Lars, Nielsen, Jens C, Videbæk, Lars, Haarbo, Jens, Korup, Eva, Bruun, Niels Eske, Brandes, Axel, Eiskjaer, Hans, Thøgersen, Anna M, Philbert, Berit T, Svendsen, Jesper Hastrup, Tfelt-Hansen, Jacob, Bauer, Axel, Rizas, Konstantinos D, Boas, Rune, Sappler, Nikolay, von Stülpnagel, Lukas, Klemm, Mathias, Dixen, Ulrik, Thune, Jens Jakob, Pehrson, Steen, Køber, Lars, Nielsen, Jens C, Videbæk, Lars, Haarbo, Jens, Korup, Eva, Bruun, Niels Eske, Brandes, Axel, Eiskjaer, Hans, Thøgersen, Anna M, Philbert, Berit T, Svendsen, Jesper Hastrup, Tfelt-Hansen, Jacob, Bauer, Axel, and Rizas, Konstantinos D

Abstract

Background: Identification of patients with non-ischemic cardiomyopathy who benefit from prophylactic implantation of a cardioverter-defibrillator (ICD) remains an unmet clinical need. We hypothesized that periodic repolarization dynamics (PRD), a marker of repolarization instability associated with sympathetic activity, could be used to identify patients that benefit from prophylactic ICD-implantation. Methods: Heart-failure (DANISH) study, in which patients with non-ischemic cardiomyopathy, left-ventricular ejection fraction (LVEF) ≤35% and elevated N-terminal pro-brain natriuretic peptides (NT-proBNP) were randomized to ICD-implantation or control group. Patients were included in the PRD-substudy if they had a 24-hour Holter monitor recording at baseline with technically acceptable ECG signals during the night hours (00:00-06.00 AM). PRD was assessed using wavelet analysis according to previously validated methods. Primary endpoint was all-cause mortality. Cox-regression models were adjusted for age, sex, NT-proBNP, estimated glomerular filtration rate, LVEF, atrial fibrillation, ventricular pacing, diabetes mellitus, cardiac resynchronization therapy and mean heart rate. We proposed PRD ≥10deg2 as exploratory cut-off value for ICD-implantation. Results: Seven-hundred and forty-eight of the 1,116 DANISH patients qualified for the PRD-substudy. During a mean follow-up period of 5.1±2.0 years, 82 of 385 patients died in the ICD group and 85 of 363 patients died in the control group (p-value=0.40). In Cox-regression analysis, PRD was independently associated with mortality (HR 1.28 [1.09-1.50] per SD increase; p-value = 0.003). Moreover, PRD was significantly associated with mortality in the control group (HR 1.51 [1.25-1.81]; p<0.001) but not in the ICD-group 1.04 [0.83-1.54]; p-value=0.71). There was a significant interaction between PRD and the effect of ICD-implantation on mortality (p-value 0.008), with patients with higher PRD having the greater benefit

Published
2022

115. QRS micro-fragmentation as a mortality predictor

Author

Arts Assistenten Cardiologie, Medische Fysiologie, Circulatory Health, Hnatkova, Katerina, Andršová, Irena, Novotný, Tomáš, Britton, Annie, Shipley, Martin, Vandenberk, Bert, Sprenkeler, David J, Junttila, Juhani, Reichlin, Tobias, Schlögl, Simon, Vos, Marc A, Friede, Tim, Bauer, Axel, Huikuri, Heikki V, Willems, Rik, Schmidt, Georg, Franz, Michael R, Sticherling, Christian, Zabel, Markus, Malik, Marek, Arts Assistenten Cardiologie, Medische Fysiologie, Circulatory Health, Hnatkova, Katerina, Andršová, Irena, Novotný, Tomáš, Britton, Annie, Shipley, Martin, Vandenberk, Bert, Sprenkeler, David J, Junttila, Juhani, Reichlin, Tobias, Schlögl, Simon, Vos, Marc A, Friede, Tim, Bauer, Axel, Huikuri, Heikki V, Willems, Rik, Schmidt, Georg, Franz, Michael R, Sticherling, Christian, Zabel, Markus, and Malik, Marek

Published
2022

119. Adult T-cells impair neonatal cardiac regeneration

Author

Dolejsi, Theresa, primary, Delgobo, Murilo, additional, Schuetz, Thomas, additional, Tortola, Luigi, additional, Heinze, Katrin G, additional, Hofmann, Ulrich, additional, Frantz, Stefan, additional, Bauer, Axel, additional, Ruschitzka, Frank, additional, Penninger, Josef M, additional, Campos Ramos, Gustavo, additional, and Haubner, Bernhard J, additional

Published
2022
Full Text
View/download PDF

121. Cardiac Magnetic Resonance Imaging versus Computed Tomography to Guide Transcatheter Aortic Valve Replacement: Study Protocol for a Randomized Trial (TAVR-CMR)

Author

Klug, Gert, primary, Reinstadler, Sebastian, additional, Troger, Felix, additional, Holzknecht, Magdalena, additional, Reindl, Martin, additional, Tiller, Christina, additional, Lechner, Ivan, additional, Fink, Priscilla, additional, Pamminger, Mathias, additional, Kremser, Christian, additional, Ulmer, Hanno, additional, Bauer, Axel, additional, Metzler, Bernhard, additional, and Mayr, Agnes, additional

Published
2022
Full Text
View/download PDF

122. Periodic Repolarization Dynamics Identifies ICD Responders in Nonischemic Cardiomyopathy: A DANISH Substudy

Author

Boas, Rune, primary, Sappler, Nikolay, additional, von Stülpnagel, Lukas, additional, Klemm, Mathias, additional, Dixen, Ulrik, additional, Thune, Jens Jakob, additional, Pehrson, Steen, additional, Køber, Lars, additional, Nielsen, Jens C., additional, Videbæk, Lars, additional, Haarbo, Jens, additional, Korup, Eva, additional, Bruun, Niels Eske, additional, Brandes, Axel, additional, Eiskjær, Hans, additional, Thøgersen, Anna M., additional, Philbert, Berit T., additional, Svendsen, Jesper Hastrup, additional, Tfelt-Hansen, Jacob, additional, Bauer, Axel, additional, and Rizas, Konstantinos D., additional

Published
2022
Full Text
View/download PDF

124. ASSOCIATION OF C-REACTIVE PROTEIN VELOCITY WITH LEFT VENTRICULAR DYSFUNCTION IN PATIENTS WITH FIRST ST-ELEVATION MYOCARDIAL INFARCTION

Author

Holzknecht, Magdalena, primary, Tiller, Christina, additional, Reindl, Martin, additional, Lechner, Ivan, additional, Fink, Priscilla, additional, Mayr, Agnes, additional, Henninger, Benjamin, additional, Brenner, Christoph, additional, Klug, Gert, additional, Bauer, Axel, additional, Metzler, Bernhard, additional, and Reinstadler, Sebastian Johannes, additional

Published
2022
Full Text
View/download PDF

125. QRS micro-fragmentation as a mortality predictor

Author

Hnatkova, Katerina, primary, Andršová, Irena, additional, Novotný, Tomáš, additional, Britton, Annie, additional, Shipley, Martin, additional, Vandenberk, Bert, additional, Sprenkeler, David J, additional, Junttila, Juhani, additional, Reichlin, Tobias, additional, Schlögl, Simon, additional, Vos, Marc A, additional, Friede, Tim, additional, Bauer, Axel, additional, Huikuri, Heikki V, additional, Willems, Rik, additional, Schmidt, Georg, additional, Franz, Michael R, additional, Sticherling, Christian, additional, Zabel, Markus, additional, and Malik, Marek, additional

Published
2022
Full Text
View/download PDF

126. Telemedical cardiac risk assessment by implantable cardiac monitors in patients after myocardial infarction with autonomic dysfunction (SMART-MI-DZHK9): a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial

Author

Bauer, Axel, primary, Sappler, Nikolay, additional, von Stülpnagel, Lukas, additional, Klemm, Mathias, additional, Schreinlechner, Michael, additional, Wenner, Felix, additional, Schier, Johannes, additional, Al Tawil, Amani, additional, Dolejsi, Theresa, additional, Krasniqi, Aresa, additional, Eiffener, Elodie, additional, Bongarth, Christa, additional, Stühlinger, Markus, additional, Huemer, Martin, additional, Gori, Tommaso, additional, Wakili, Reza, additional, Sahin, Riza, additional, Schwinger, Robert, additional, Lutz, Matthias, additional, Luik, Armin, additional, Gessler, Nele, additional, Clemmensen, Peter, additional, Linke, Axel, additional, Maier, Lars S, additional, Hinterseer, Martin, additional, Busch, Mathias C, additional, Blaschke, Florian, additional, Sack, Stefan, additional, Lennerz, Carsten, additional, Licka, Manuela, additional, Tilz, Roland R, additional, Ukena, Christian, additional, Ehrlich, Joachim R, additional, Zabel, Markus, additional, Schmidt, Georg, additional, Mansmann, Ulrich, additional, Kääb, Stefan, additional, Rizas, Konstantinos D, additional, Massberg, Steffen, additional, May, Andreas, additional, Seitzer, Peter, additional, Schmidt, Roland, additional, Keta, Dritan, additional, Janke, Viktoria, additional, Schläger, Christian, additional, André, Elisabeth, additional, Brandt, Niels, additional, Schön, Alexandra, additional, Zollner, Alfred, additional, Freyer, Luisa, additional, Hamm, Wolfgang, additional, Beil, Johannes, additional, Strüven, Anna Katharina, additional, Loew, Anja, additional, Fichtner, Stephanie, additional, Lange, Philipp, additional, Grabmeier, Ulrich, additional, Estner, Heidi, additional, Bengel, Philipp, additional, Lüthje, Lars, additional, Kirova, Aleksandra, additional, Fischer, Thomas, additional, Bergau, Leonard, additional, Herting, Jonas, additional, Schlögl, Simon, additional, Haarmann, Helge, additional, Schlögl (Illes), Klaudia, additional, Uecer, Ekrem, additional, Sag, Sabine, additional, Tafelmeier, Maria, additional, Jungbauer, Carsten, additional, Fredersdorf-Hahn, Sabine, additional, Strack, Christina, additional, Seither, Benedikt, additional, Seegers, Joachim, additional, Millenaar, Dominic, additional, Wintrich, Jan, additional, Fischer, Patrick, additional, Buob, Axel, additional, Razouk, Amjad, additional, Demming, Thomas, additional, Frank, Johanne, additional, Kühl, Constantin, additional, Ellendt, Ulrike, additional, Sandrock, Sarah, additional, Gänsbacher, Julia, additional, Cupa, Janosch, additional, Sinnecker, Daniel, additional, Laugwitz, Karl-Ludwig, additional, Steger, Alexander, additional, Berkefeld, Anna, additional, Schinke, Karin, additional, Barthel, Petra, additional, Dommasch, Michael, additional, Amadei, Maiwand, additional, Hindricks, Gerhard, additional, Obradovic, Danilo, additional, Döring, Michael, additional, Bode, Kerstin, additional, Hilbert, Sebastian, additional, Löbe, Susanne, additional, Knopp, Helge, additional, König, Sebastian, additional, John, Silke, additional, Schöne, Katharina, additional, Hartung, Philipp, additional, Binner, Christian, additional, Meyer-Zürn, Christine, additional, Duckheim, Martin, additional, Eick, Christian, additional, Simpfle, Fabian, additional, Schreieck, Jürgen, additional, Mizera, Lars, additional, Tscholl, Verena, additional, Steinbeck, Lisa, additional, Güc, Nadija, additional, Schatz, Anne-Sophie, additional, Attanasio, Philipp, additional, Heuberger, Andrea, additional, Roser, Mattias, additional, Bellmann, Barbara, additional, Nagel, Patrick, additional, Biewener, Sebastian, additional, Suhail, Saba, additional, Juri, Benjamin, additional, Meyer, Christian, additional, Wiilems, Stephan, additional, Jungen, Christiane, additional, Schmitt, Susanne, additional, Münkerer, Paula, additional, Vogler, Julia, additional, Kaiser, Lukas, additional, Schäffer, Benjamin, additional, Nies, Moritz, additional, Tönnis, Tobias, additional, Fluschnik, Nina, additional, Grahn, Hanno, additional, Waldeyer, Christoph, additional, Kany, Shinwan, additional, Sörensen, Nils Arne, additional, Winkelmann, Simon, additional, Akbulak, Özge, additional, Gosau, Nils Arne, additional, Würger, Tilman, additional, Arnold, Natalie, additional, Geßler, Nele, additional, Jobs, Alexander, additional, Münkler, Paula, additional, Rausch, Stefan, additional, Köster, Jelena, additional, Brüggemann, Ben, additional, Abdin, Amr, additional, Wacker, Christian, additional, Grotherr, Philipp, additional, Fries, Bastian, additional, Faust, Maximilian, additional, Steuer, Stefanie, additional, Swojanowsky, Patrick, additional, Willems, Stephan, additional, Portz, Nathaniel, additional, Ujeyl, Amar, additional, Krüger, Matthias, additional, Gramlich, Robert, additional, Köhler, Till, additional, Sause, Armin, additional, Nover, Ina, additional, Ziakos, Athanasios-Panagiotis, additional, Ciobanu, Veaceslav, additional, Spelsberg, Norman, additional, Siebermair, Johannes, additional, Mahabadi, Amir-Abbas, additional, Köhler, Miriam, additional, Vonderlin, Nadine, additional, Riesinger, Lisa, additional, Abdiu, Edison, additional, Bachmann, Anja, additional, Frenzel, Marie, additional, Hummel, Astrid, additional, Lehnert, Kristin, additional, Krüger, Anne, additional, Busse, Franke, additional, Napp, Andreas, additional, Müller-Wieland, Dirk, additional, Battermann, Simone, additional, Lacour, Philipp, additional, Trippel, Tobias, additional, Beetz, Nick Lasse, additional, Schleußner, Leonhard, additional, Zach, Veronika, additional, Rozados, Christina, additional, Mudra, Harald, additional, Staubach, Stephan, additional, Illmann, Alexander, additional, Joner, Michael, additional, Bock, Matthias, additional, Kolb, Christof, additional, Koch, Tobias, additional, Fröhlich, Rebecca, additional, Lenz, Tobias, additional, Fuchs, Patrick, additional, Freißmuth, Markus, additional, Grebmer, Christian, additional, Kuschyk, Jürgen, additional, Kranert, Malte, additional, Fastenrath, Fabian, additional, Yücel, Gökhan, additional, Rudic, Boris, additional, Würfel, Sarah, additional, Römer, Albrecht, additional, Böhmer, Andreas, additional, Honold, Jörg, additional, Georgopoulos, Stamatis, additional, Gleirscher, Lukas, additional, Lederle, Susanne, additional, Chaplygin, Artem, additional, Pauschinger, Matthias, additional, Brinker-Paschke, Andrea, additional, Kropacek, Jana, additional, Eckardt, Lars, additional, Ellermann, Christian, additional, Bode, Niklas, additional, Reinke, Florian, additional, Engelke, Hauke, additional, Höllriegel, Robert, additional, Woitek, Felix, additional, Winzer, Ephraim, additional, Ibrahim, Karim, additional, Pflücke, Christian, additional, Ende, Georg, additional, Speiser, Uwe, additional, Haußig, Stephan, additional, Wachter, Rolf, additional, Uhe, Tobias, additional, Konrad, Torsten, additional, Zitron, Edgar, additional, Destani, Jeton, additional, Fu, Fangyi, additional, Al Said, Samer, additional, Kaya, Ziya, additional, Schgör, Wilfried, additional, and Senoner, Thomas, additional

Published
2022
Full Text
View/download PDF

135. Clinical effectiveness of primary prevention implantable cardioverter-defibrillators: results of the EU-CERT-ICD controlled multicentre cohort study

Author

Zabel, Markus, Willems, Rik, Lubinski, Andrzej, Bauer, Axel, Brugada, Josep, Conen, David, Flevari, Panagiota, Hasenfuß, Gerd, Svetlosak, Martin, Huikuri, Heikki V, Malik, Marek, Pavlović, Nikola, Schmidt, Georg, Sritharan, Rajevaa, Schlögl, Simon, Szavits-Nossan, Janko, Traykov, Vassil, Tuinenburg, Anton E, Willich, Stefan N, Harden, Markus, Friede, Tim, Svendsen, Jesper Hastrup, Sticherling, Christian, Merkely, Béla, Perge, Peter, Sallo, Zoltan, Szeplaki, Gabor, Szegedi, Nandor, Nagy, Klaudia Vivien, Lüthje, Lars, Sritharan, R, Haarmann, Helge, Bergau, Leonard, Seegers, Joachim, Munoz- Exposito, Pascal, Tichelbäcker, Tobias, Kirova, Aleksandra, Hnatkova, Katerina, Vos, Marc A, Reinhold, Thomas, Vandenberk, Bert, Klinika, Magdalena, Rotkvić, L, Flevari, Panayota, Katsimardos, Andreas, Katsaras, Dimitrios, Hatala, Robert, Kuczejko, Tomasz, Hansen, Jim, Manola, Šime, Vinter, Ozren, Benko, Ivica, Tuinenburg, Anton, Sprenkeler, David, Smoczynska, A, Vos, M A, Meyer-Zürn, Christine, Eick, Christian, Arbelo, Elena, Kaliska, Gabriela, Martinek, Jozef, Dommasch, Michael, Steger, Alexander, Kääb, Stefan, Sinner, Moritz F, Rizas, Konstantinos D, Hamm, Wolfgang, Traykov, V, Cygankiewicz, Iwona, Ptaszyński, Pawel, Kaczmarek, K, Poddebska, I, Iovev, Svetoslav, Novotný, Tomáš, Kozak, Milan, Huikuri, Heikki, Kenttä, Tuomas, Pelli, Ari, Kasprzak, Jaroslaw D, Qavoq, Dariusz, Brusich, Sandro, Avdovic, Ervin, Klasan, Marina, Galuszka, Jan, Taborsky, Milos, Velchev, Vasil, Dissmann, Rüdiger, Shalganov, T, Guzik, P, Krauze, T, Bimmel, Dieter, Lieberz, Christiane, Ludwigsburg, Klinikum, Stefanow, Stefan, Rüb, Norman, Wolpert, Christian, Meier, Lars S, Behrens, Steffen, Jurisic, Zrinka, Braunschweig, Frieder, Blaschke, Florian, Pieske, Burkert, Bakotic, Zoran, Anic, Ante, Weiden, Klinikum, Schwinger, Robert H G, Platonov, Pyotr, Grönefeld, Gerian, Klingenheben, Thomas, and EU-CERT-ICD Study Investigators

Subjects
medicine.medical_specialty, medicine.medical_treatment, Implantable cardioverter-defibrillator, Risk factors, Mortality, Sudden cardiac death, 030204 cardiovascular system & hematology, Ventricular Function, Left, Cohort Studies, EU-CERT-ICD Study Investigators, 03 medical and health sciences, 0302 clinical medicine, Clinical Research, Internal medicine, medicine, Clinical endpoint, Humans, AcademicSubjects/MED00200, Prospective Studies, 030212 general & internal medicine, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine, 1102 Cardiorespiratory Medicine and Haematology, Aged, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina, Heart Failure, Ejection fraction, Ischemic cardiomyopathy, business.industry, Hazard ratio, Stroke Volume, 1103 Clinical Sciences, Dilated cardiomyopathy, medicine.disease, Confidence interval, Defibrillators, Implantable, 3. Good health, Europe, Primary Prevention, Death, Sudden, Cardiac, Treatment Outcome, Cardiovascular System & Hematology, Implantable cardioverter-defibrillator, Risk factors, Mortality, Sudden cardiac death, Cardiology and Cardiovascular Medicine, business, Cohort study
Abstract

Aims The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter-Defibrillators (EU-CERT-ICD), a prospective investigator-initiated, controlled cohort study, was conducted in 44 centres and 15 European countries. It aimed to assess current clinical effectiveness of primary prevention ICD therapy. Methods and results We recruited 2327 patients with ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and guideline indications for prophylactic ICD implantation. Primary endpoint was all-cause mortality. Clinical characteristics, medications, resting, and 12-lead Holter electrocardiograms (ECGs) were documented at enrolment baseline. Baseline and follow-up (FU) data from 2247 patients were analysable, 1516 patients before first ICD implantation (ICD group) and 731 patients without ICD serving as controls. Multivariable models and propensity scoring for adjustment were used to compare the two groups for mortality. During mean FU of 2.4 ± 1.1 years, 342 deaths occurred (6.3%/years annualized mortality, 5.6%/years in the ICD group vs. 9.2%/years in controls), favouring ICD treatment [unadjusted hazard ratio (HR) 0.682, 95% confidence interval (CI) 0.537–0.865, P = 0.0016]. Multivariable mortality predictors included age, left ventricular ejection fraction (LVEF), New York Heart Association class Conclusion In contemporary ICM/DCM patients (LVEF ≤35%, narrow QRS), primary prophylactic ICD treatment was associated with a 27% lower mortality after adjustment. There appear to be patients with less survival advantage, such as older patients or diabetics.

Published
2020

136. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

Author

Zeppenfeld, Katja, Tfelt-Hansen, Jacob, de Riva, Marta, Winkel, Bo Gregers, Behr, Elijah R, Blom, Nico A, Charron, Philippe, Corrado, Domenico, Dagres, Nikolaos, de Chillou, Christian, Eckardt, Lars, Friede, Tim, Haugaa, Kristina H, Hocini, Mélèze, Lambiase, Pier D, Marijon, Eloi, Merino, Jose L, Peichl, Petr, Priori, Silvia G, Reichlin, Tobias, Schulz-Menger, Jeanette, Sticherling, Christian, Tzeis, Stylianos, Verstrael, Axel, Volterrani, Maurizio, Cikes, Maja, Kirchhof, Paulus, Abdelhamid, Magdy, Aboyans, Victor, Arbelo, Elena, Arribas, Fernando, Asteggiano, Riccardo, Basso, Cristina, Bauer, Axel, Bertaglia, Emanuele, Biering-Sørensen, Tor, Blomström-Lundqvist, Carina, Borger, Michael A, Čelutkienė, Jelena, Cosyns, Bernard, Falk, Volkmar, Fauchier, Laurent, Gorenek, Bulent, Halvorsen, Sigrun, Hatala, Robert, Heidbuchel, Hein, Kaab, Stefan, Konradi, Aleksandra, Koskinas, Konstantinos C, Kotecha, Dipak, Landmesser, Ulf, Lewis, Basil S, Linhart, Ales, Løchen, Maja-Lisa, Lund, Lars H, Metzner, Andreas, Mindham, Richard, Nielsen, Jens Cosedis, Norekvål, Tone M, Patten, Monica, Prescott, Eva, Rakisheva, Amina, Remme, Carol Ann, Roca-Luque, Ivo, Sarkozy, Andrea, Scherr, Daniel, Sitges, Marta, Touyz, Rhian M, Van Mieghem, Nicolas, Velagic, Vedran, Viskin, Sami, Volders, Paul G A, Pediatrics, Physiology, ACS - Heart failure & arrhythmias, Paediatric Cardiology, Cardiology, and APH - Methodology

Subjects
Genetic testing, Cardiac magnetic resonance, Sudden death, Arrhythmias, Cardiac, Ventricular tachycardia, Primary electrical disease, Guidelines, Recommendations, Chronic coronary artery disease, Risk calculator, Sudden cardiac death, Death, Sudden, Cardiac, Implantable cardioverter defibrillator, Ventricular arrhythmia, Humans, Catheter ablation, Anti-arrhythmic drugs, Ventricular fibrillation, Cardiology and Cardiovascular Medicine, 610 Medicine & health, Cardiomyopathies, Premature ventricular complex, Risk stratification
Published
2022

138. U-Shaped Association of the Heart Rate Variability Triangular Index and Mortality in Hemodialysis Patients With Atrial Fibrillation

Author

Braunisch, Matthias C., primary, Mayer, Christopher C., additional, Werfel, Stanislas, additional, Bauer, Axel, additional, Haller, Bernhard, additional, Lorenz, Georg, additional, Günthner, Roman, additional, Matschkal, Julia, additional, Bachmann, Quirin, additional, Thunich, Stephan, additional, Schlegl, Michaela, additional, Ludwig, Maximilian, additional, Holzmann-Littig, Christopher, additional, Assali, Tarek, additional, Pachmann, Martin, additional, Küchle, Claudius, additional, Renders, Lutz, additional, Wassertheurer, Siegfried, additional, Müller, Alexander, additional, Schmidt, Georg, additional, Heemann, Uwe, additional, Malik, Marek, additional, and Schmaderer, Christoph, additional

Published
2021
Full Text
View/download PDF

139. Association of plasma interleukin-6 with infarct size, reperfusion injury, and adverse remodelling after ST-elevation myocardial infarction

Author

Tiller, Christina, primary, Reindl, Martin, additional, Holzknecht, Magdalena, additional, Lechner, Ivan, additional, Schwaiger, Johannes, additional, Brenner, Christoph, additional, Mayr, Agnes, additional, Klug, Gert, additional, Bauer, Axel, additional, Metzler, Bernhard, additional, and Reinstadler, Sebastian J, additional

Published
2021
Full Text
View/download PDF

140. Association of C-Reactive Protein Velocity with Early Left Ventricular Dysfunction in Patients with First ST-Elevation Myocardial Infarction

Author

Holzknecht, Magdalena, primary, Tiller, Christina, additional, Reindl, Martin, additional, Lechner, Ivan, additional, Fink, Priscilla, additional, Lunger, Patrick, additional, Mayr, Agnes, additional, Henninger, Benjamin, additional, Brenner, Christoph, additional, Klug, Gert, additional, Bauer, Axel, additional, Metzler, Bernhard, additional, and Reinstadler, Sebastian Johannes, additional

Published
2021
Full Text
View/download PDF

141. Prognostic value of depressed cardiac index after STEMI: a phase-contrast magnetic resonance study

Author

Schwaiger, Johannes P, primary, Reinstadler, Sebastian J, additional, Holzknecht, Magdalena, additional, Tiller, Christina, additional, Reindl, Martin, additional, Begle, Jana, additional, Lechner, Ivan, additional, Lamina, Claudia, additional, Mayr, Agnes, additional, Graziadei, Ivo, additional, Bauer, Axel, additional, Metzler, Bernhard, additional, and Klug, Gert, additional

Published
2021
Full Text
View/download PDF

142. Cardiac magnetic resonance imaging improves prognostic stratification of patients with ST-elevation myocardial infarction and preserved ejection fraction

Author

Reindl, Martin, primary, Stiermaier, Thomas, additional, Lechner, Ivan, additional, Tiller, Christina, additional, Holzknecht, Magdalena, additional, Mayr, Agnes, additional, Schwaiger, Johannes P, additional, Brenner, Christoph, additional, Klug, Gert, additional, Bauer, Axel, additional, Thiele, Holger, additional, Feistritzer, Hans-Josef, additional, Metzler, Bernhard, additional, Eitel, Ingo, additional, and Reinstadler, Sebastian J, additional

Published
2021
Full Text
View/download PDF

143. Sympathetic activity--associated periodic repolarization dynamics predict mortality following myocardial infarction

Author

Rizas, Konstantinos D., Nieminen, Tuomo, Barthel, Petra, Zurn, Christine S., Kahonen, Mika, Viik, Jari, Lehtimaki, Terho, Nikus, Kjell, Eick, Christian, Greiner, Tim O., Wendel, Hans P., Seizer, Peter, Schreieck, Jurgen, Gawaz, Meinrad, Schmidt, Georg, and Bauer, Axel

Subjects
Nervous system, Sympathetic -- Physiological aspects -- Research, Heart beat -- Research, Cardiac arrest -- Research, Health care industry
Abstract

Background. Enhanced sympathetic activity at the ventricular myocardium can destabilize repolarization, increasing the risk of death. Sympathetic activity is known to cluster in low-frequency bursts; therefore, we hypothesized that sympathetic activity induces periodic low-frequency changes of repolarization. We developed a technique to assess the sympathetic effect on repolarization and identified periodic components in the low-frequency spectral range (≤ 0.1 Hz), which we termed periodic repolarization dynamics (PRD). Methods. We investigated the physiological properties of PRD in multiple experimental studies, including a swine model of steady-state ventilation (n = 7) and human studies involving fixed atrial pacing (n = 10), passive head-up tilt testing (n = 11), low-intensity exercise testing (n = 11), and beta blockade (n = 10). We tested the prognostic power of PRD in 908 survivors of acute myocardial infarction (MI). Finally, we tested the predictive values of PRD and T-wave alternans (TWA) in 2,965 patients undergoing clinically indicated exercise testing. Results. PRD was not related to underlying respiratory activity (P < 0.001) or heart-rate variability (P = 0.002). Furthermore, PRD was enhanced by activation of the sympathetic nervous system, and pharmacological blockade of sympathetic nervous system activity suppressed PRD (P < 0.005 for both). Increased PRD was the strongest single risk predictor of 5-year total mortality (hazard ratio 4.75, 95% CI 2.94-7.66; P < 0.001) after acute MI. In patients undergoing exercise testing, the predictive value of PRD was strong and complementary to that of TWA. Conclusion. We have described and identified low-frequency rhythmic modulations of repolarization that are associated with sympathetic activity. Increased PRD can be used as a predictor of mortality in survivors of acute MI and patients undergoing exercise testing. Trial registration. ClinicalTrials.gov NCT00196274. Funding. This study was funded by Angewandte Klinische Forschung, University of Tubingen (252-1-0)., Introduction Sudden cardiac death (SCD) is the single most common cause of death in the industrialized world (1). A substantial proportion of SCD cases occur in patients after myocardial infarction [...]

Published
2014
Full Text
View/download PDF

150. Determinants and prognostic relevance of aortic stiffness in patients with recent ST-elevation myocardial infarction

Author

Lechner, Ivan, primary, Reindl, Martin, additional, Tiller, Christina, additional, Holzknecht, Magdalena, additional, Niederreiter, Sarah, additional, Mayr, Agnes, additional, Klug, Gert, additional, Brenner, Christoph, additional, Bauer, Axel, additional, Metzler, Bernhard, additional, and Reinstadler, Sebastian Johannes, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results