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106. Failure to Rescue – a Closer Look at Mortality Rates Has No Added Value for Hospital Comparisons but Is Useful for Team Quality Assessment in Abdominal Aortic Aneurysm Surgery in The Netherlands

Author

Lijftogt, Niki, primary, Karthaus, Eleonora G., additional, Vahl, Anco, additional, van Zwet, Erik W., additional, van der Willik, Esmee M., additional, Tollenaar, Robertus A.E.M., additional, Hamming, Jaap F., additional, Wouters, Michel W.J.M., additional, Van den Akker, L.H., additional, Van den Akker, P.J., additional, Akkersdijk, G.J., additional, Akkersdijk, G.P., additional, Akkersdijk, W.L., additional, van Andringa de Kempenaer, M.G., additional, Arts, C.H., additional, Avontuur, J.A., additional, Baal, J.G., additional, Bakker, O.J., additional, Balm, R., additional, Barendregt, W.B., additional, Bender, M.H., additional, Bendermacher, B.L., additional, van den Berg, M., additional, Berger, P., additional, Beuk, R.J., additional, Blankensteijn, J.D., additional, Bleker, R.J., additional, Bockel, J.H., additional, Bodegom, M.E., additional, Bogt, K.E., additional, Boll, A.P., additional, Booster, M.H., additional, Borger van der Burg, B.L., additional, de Borst, G.J., additional, Bos-van Rossum, W.T., additional, Bosma, J., additional, Botman, J.M., additional, Bouwman, L.H., additional, Breek, J.C., additional, Brehm, V., additional, Brinckman, M.J., additional, van den Broek, T.H., additional, Brom, H.L., additional, de Bruijn, M.T., additional, de Bruin, J.L., additional, Brummel, P., additional, van Brussel, J.P., additional, Buijk, S.E., additional, Buimer, M.G., additional, Burger, D.H., additional, Buscher, H.C., additional, den Butter, G., additional, Cancrinus, E., additional, Castenmiller, P.H., additional, Cazander, G., additional, Coveliers, H.M., additional, Cuypers, P.H., additional, Daemen, J.H., additional, Dawson, I., additional, Derom, A.F., additional, Dijkema, A.R., additional, Diks, J., additional, Dinkelman, M.K., additional, Dirven, M., additional, Dolmans, D.E., additional, van Doorn, R.C., additional, van Dortmont, L.M., additional, van der Eb, M.M., additional, Eefting, D., additional, van Eijck, G.J., additional, Elshof, J.W., additional, Elsman, B.H., additional, van der Elst, A., additional, van Engeland, M.I., additional, van Eps, R.G., additional, Faber, M.J., additional, de Fijter, W.M., additional, Fioole, B., additional, Fritschy, W.M., additional, Geelkerken, R.H., additional, van Gent, W.B., additional, Glade, G.J., additional, Govaert, B., additional, Groenendijk, R.P., additional, de Groot, H.G., additional, van den Haak, R.F., additional, de Haan, E.F., additional, Hajer, G.F., additional, Hamming, J.F., additional, van Hattum, E.S., additional, Hazenberg, C.E., additional, Hedeman Joosten, P.P., additional, Helleman, J.N., additional, van der Hem, L.G., additional, Hendriks, J.M., additional, van Herwaarden, J.A., additional, Heyligers, J.M., additional, Hinnen, J.W., additional, Hissink, R.J., additional, Ho, G.H., additional, den Hoed, P.T., additional, Hoedt, M.T., additional, van Hoek, F., additional, Hoencamp, R., additional, Hoffmann, W.H., additional, Hoksbergen, A.W., additional, Hollander, E.J., additional, Huisman, L.C., additional, Hulsebos, R.G., additional, Huntjens, K.M., additional, Idu, M.M., additional, Jacobs, M.J., additional, van der Jagt, M.F., additional, Jansbeken, J.R., additional, Janssen, R.J., additional, Jiang, H.H., additional, de Jong, S.C., additional, Jongkind, V., additional, Kapma, M.R., additional, Keller, B.P., additional, Khodadade Jahrome, A., additional, Kievit, J.K., additional, Klemm, P.L., additional, Klinkert, P., additional, Knippenberg, B., additional, Koedam, N.A., additional, Koelemaij, M.J., additional, Kolkert, J.L., additional, Koning, G.G., additional, Koning, O.H., additional, Krasznai, A.G., additional, Krol, R.M., additional, Kropman, R.H., additional, Kruse, R.R., additional, van der Laan, L., additional, van der Laan, M.J., additional, van Laanen, J.H., additional, Lardenoye, J.H., additional, Lawson, J.A., additional, Legemate, D.A., additional, Leijdekkers, V.J., additional, Lemson, M.S., additional, Lensvelt, M.M., additional, Lijkwan, M.A., additional, Lind, R.C., additional, van der Linden, F.T., additional, Liqui Lung, P.F., additional, Loos, M.J., additional, Loubert, M.C., additional, Mahmoud, D.E., additional, Manshanden, C.G., additional, Mattens, E.C., additional, Meerwaldt, R., additional, Mees, B.M., additional, Metz, R., additional, Minnee, R.C., additional, de Mol van Otterloo, J.C., additional, Moll, F.L., additional, Montauban van Swijndregt, Y.C., additional, Morak, M.J., additional, van de Mortel, R.H., additional, Mulder, W., additional, Nagesser, S.K., additional, Naves, C.C., additional, Nederhoed, J.H., additional, Nevenzel-Putters, A.M., additional, de Nie, A.J., additional, Nieuwenhuis, D.H., additional, Nieuwenhuizen, J., additional, van Nieuwenhuizen, R.C., additional, Nio, D., additional, Oomen, A.P., additional, Oranen, B.I., additional, Oskam, J., additional, Palamba, H.W., additional, Peppelenbosch, A.G., additional, van Petersen, A.S., additional, Peterson, T.F., additional, Petri, B.J., additional, Pierie, M.E., additional, Ploeg, A.J., additional, Pol, R.A., additional, Ponfoort, E.D., additional, Poyck, P.P., additional, Prent, A., additional, ten Raa, S., additional, Raymakers, J.T., additional, Reichart, M., additional, Reichmann, B.L., additional, Reijnen, M.M., additional, Rijbroek, A., additional, van Rijn, M.J., additional, de Roo, R.A., additional, Rouwet, E.V., additional, Rupert, C.G., additional, Saleem, B.R., additional, van Sambeek, M.R., additional, Samyn, M.G., additional, van ’t Sant, H.P., additional, van Schaik, J., additional, van Schaik, P.M., additional, Scharn, D.M., additional, Scheltinga, M.R., additional, Schepers, A., additional, Schlejen, P.M., additional, Schlosser, F.J., additional, Schol, F.P., additional, Schouten, O., additional, Schreinemacher, M.H., additional, Schreve, M.A., additional, Schurink, G.W., additional, Sikkink, C.J., additional, Siroen, M.P., additional, te Slaa, A., additional, Smeets, H.J., additional, Smeets, L., additional, de Smet, A.A., additional, de Smit, P., additional, Smit, P.C., additional, Smits, T.M., additional, Snoeijs, M.G., additional, Sondakh, A.O., additional, van der Steenhoven, T.J., additional, van Sterkenburg, S.M., additional, Stigter, D.A., additional, Stigter, H., additional, Strating, R.P., additional, Stultiëns, G.N., additional, Sybrandy, J.E., additional, Teijink, J.A., additional, Telgenkamp, B.J., additional, Testroote, M.J., additional, The, R.M., additional, Thijsse, W.J., additional, Tielliu, I.F., additional, van Tongeren, R.B., additional, Toorop, R.J., additional, Tordoir, J.H., additional, Tournoij, E., additional, Truijers, M., additional, Türkcan, K., additional, Tutein Nolthenius, R.P., additional, Ünlü, Ç., additional, Vafi, A.A., additional, Vahl, A.C., additional, Veen, E.J., additional, Veger, H.T., additional, Veldman, M.G., additional, Verhagen, H.J., additional, Verhoeven, B.A., additional, Vermeulen, C.F., additional, Vermeulen, E.G., additional, Vierhout, B.P., additional, Visser, M.J., additional, van der Vliet, J.A., additional, Vlijmen-van Keulen, C.J., additional, Voesten, H.G., additional, Voorhoeve, R., additional, Vos, A.W., additional, de Vos, B., additional, Vos, G.A., additional, Vriens, B.H., additional, Vriens, P.W., additional, de Vries, A.C., additional, de Vries, J.P., additional, de Vries, M., additional, van der Waal, C., additional, Waasdorp, E.J., additional, Wallis de Vries, B.M., additional, van Walraven, L.A., additional, van Wanroij, J.L., additional, Warlé, M.C., additional, van Weel, V., additional, van Well, A.M., additional, Welten, G.M., additional, Welten, R.J., additional, Wever, J.J., additional, Wiersema, A.M., additional, Wikkeling, O.R., additional, Willaert, W.I., additional, Wille, J., additional, Willems, M.C., additional, Willigendael, E.M., additional, Wisselink, W., additional, Witte, M.E., additional, Wittens, C.H., additional, Wolf-de Jonge, I.C., additional, Yazar, O., additional, Zeebregts, C.J., additional, and van Zeeland, M.L., additional

Published
2018
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108. The Dutch Audit of Carotid Interventions: Transparency in Quality of Carotid Endarterectomy in Symptomatic Patients in the Netherlands

Author

Karthaus, Eleonora G., primary, Vahl, Anco, additional, Kuhrij, Laurien S., additional, Elsman, Bernard H.P., additional, Geelkerken, Robert H., additional, Wouters, Michel W.J.M., additional, Hamming, Jaap F., additional, de Borst, Gert J., additional, Van den Akker, L.H., additional, Van den Akker, P.J., additional, Akkersdijk, G.J., additional, Akkersdijk, G.P., additional, Akkersdijk, W.L., additional, van Andringa de Kempenaer, M.G., additional, Arts, C.H., additional, Avontuur, J.A., additional, Baal, J.G., additional, Bakker, O.J., additional, Balm, R., additional, Barendregt, W.B., additional, Bender, M.H., additional, Bendermacher, B.L., additional, van den Berg, M., additional, Berger, P., additional, Beuk, R.J., additional, Blankensteijn, J.D., additional, Bleker, R.J., additional, Bockel, J.H., additional, Bodegom, M.E., additional, Bogt, K.E., additional, Boll, A.P., additional, Booster, M.H., additional, Borger van der Burg, B.L., additional, de Borst, G.J., additional, Bos- van Rossum, W.T., additional, Bosma, J., additional, Botman, J.M., additional, Bouwman, L.H., additional, Breek, J.C., additional, Brehm, V., additional, Brinckman, M.J., additional, van den Broek, T.H., additional, Brom, H.L., additional, de Bruijn, M.T., additional, de Bruin, J.L., additional, Brummel, P., additional, van Brussel, J.P., additional, Buijk, S.E., additional, Buimer, M.G., additional, Burger, D.H., additional, Buscher, H.C., additional, den Butter, G., additional, Cancrinus, E., additional, Castenmiller, P.H., additional, Cazander, G., additional, Coveliers, H.M., additional, Cuypers, P.H., additional, Daemen, J.H., additional, Dawson, I., additional, Derom, A.F., additional, Dijkema, A.R., additional, Diks, J., additional, Dinkelman, M.K., additional, Dirven, M., additional, Dolmans, D.E., additional, van Doorn, R.C., additional, van Dortmont, L.M., additional, van der Eb, M.M., additional, Eefting, D., additional, van Eijck, G.J., additional, Elshof, J.W., additional, Elsman, B.H., additional, van der Elst, A., additional, van Engeland, M.I., additional, van Eps, R.G., additional, Faber, M.J., additional, de Fijter, W.M., additional, Fioole, B., additional, Fritschy, W.M., additional, Geelkerken, R.H., additional, van Gent, W.B., additional, Glade, G.J., additional, Govaert, B., additional, Groenendijk, R.P., additional, de Groot, H.G., additional, van den Haak, R.F., additional, de Haan, E.F., additional, Hajer, G.F., additional, Hamming, J.F., additional, van Hattum, E.S., additional, Hazenberg, C.E., additional, Hedeman Joosten, P.P., additional, Helleman, J.N., additional, van der Hem, L.G., additional, Hendriks, J.M., additional, van Herwaarden, J.A., additional, Heyligers, J.M., additional, Hinnen, J.W., additional, Hissink, R.J., additional, Ho, G.H., additional, den Hoed, P.T., additional, Hoedt, M.T., additional, van Hoek, F., additional, Hoencamp, R., additional, Hoffmann, W.H., additional, Hoksbergen, A.W., additional, Hollander, E.J., additional, Huisman, L.C., additional, Hulsebos, R.G., additional, Huntjens, K.M., additional, Idu, M.M., additional, Jacobs, M.J., additional, van der Jagt, M.F., additional, Jansbeken, J.R., additional, Janssen, R.J., additional, Jiang, H.H., additional, de Jong, S.C., additional, Jongkind, V., additional, Kapma, M.R., additional, Keller, B.P., additional, Khodadade Jahrome, A., additional, Kievit, J.K., additional, Klemm, P.L., additional, Klinkert, P., additional, Knippenberg, B., additional, Koedam, N.A., additional, Koelemaij, M.J., additional, Kolkert, J.L., additional, Koning, G.G., additional, Koning, O.H., additional, Krasznai, A.G., additional, Krol, R.M., additional, Kropman, R.H., additional, Kruse, R.R., additional, van der Laan, L., additional, van der Laan, M.J., additional, van Laanen, J.H., additional, Lardenoye, J.H., additional, Lawson, J.A., additional, Legemate, D.A., additional, Leijdekkers, V.J., additional, Lemson, M.S., additional, Lensvelt, M.M., additional, Lijkwan, M.A., additional, Lind, R.C., additional, van der Linden, F.T., additional, Liqui Lung, P.F., additional, Loos, M.J., additional, Loubert, M.C., additional, Mahmoud, D.E., additional, Manshanden, C.G., additional, Mattens, E.C., additional, Meerwaldt, R., additional, Mees, B.M., additional, Metz, R., additional, Minnee, R.C., additional, de Mol van Otterloo, J.C., additional, Moll, F.L., additional, Montauban van Swijndregt, Y.C., additional, Morak, M.J., additional, van de Mortel, R.H., additional, Mulder, W., additional, Nagesser, S.K., additional, Naves, C.C., additional, Nederhoed, J.H., additional, Nevenzel-Putters, A.M., additional, de Nie, A.J., additional, Nieuwenhuis, D.H., additional, Nieuwenhuizen, J., additional, van Nieuwenhuizen, R.C., additional, Nio, D., additional, Oomen, A.P., additional, Oranen, B.I., additional, Oskam, J., additional, Palamba, H.W., additional, Peppelenbosch, A.G., additional, van Petersen, A.S., additional, Peterson, T.F., additional, Petri, B.J., additional, Pierie, M.E., additional, Ploeg, A.J., additional, Pol, R.A., additional, Ponfoort, E.D., additional, Poyck, P.P., additional, Prent, A., additional, ten Raa, S., additional, Raymakers, J.T., additional, Reichart, M., additional, Reichmann, B.L., additional, Reijnen, M.M., additional, Rijbroek, A., additional, van Rijn, M.J., additional, de Roo, R.A., additional, Rouwet, E.V., additional, Rupert, C.G., additional, Saleem, B.R., additional, van Sambeek, M.R., additional, Samyn, M.G., additional, van 't Sant, H.P., additional, van Schaik, J., additional, van Schaik, P.M., additional, Scharn, D.M., additional, Scheltinga, M.R., additional, Schepers, A., additional, Schlejen, P.M., additional, Schlosser, F.J., additional, Schol, F.P., additional, Schouten, O., additional, Schreinemacher, M.H., additional, Schreve, M.A., additional, Schurink, G.W., additional, Sikkink, C.J., additional, Siroen, M.P., additional, te Slaa, A., additional, Smeets, H.J., additional, Smeets, L., additional, de Smet, A.A., additional, de Smit, P., additional, Smit, P.C., additional, Smits, T.M., additional, Snoeijs, M.G., additional, Sondakh, A.O., additional, van der Steenhoven, T.J., additional, van Sterkenburg, S.M., additional, Stigter, D.A., additional, Stigter, H., additional, Strating, R.P., additional, Stultiëns, D., additional, Sybrandy, J.E., additional, Teijink, J.A., additional, Telgenkamp, B.J., additional, Testroote, M.J., additional, The, R.M., additional, Thijsse, W.J., additional, Tielliu, I.F., additional, van Tongeren, R.B., additional, Toorop, R.J., additional, Tordoir, J.H., additional, Tournoij, E., additional, Truijers, M., additional, Türkcan, K., additional, Tutein Nolthenius, R.P., additional, Ünlü, Ç., additional, Vafi, A.A., additional, Vahl, A.C., additional, Veen, E.J., additional, Veger, H.T., additional, Veldman, M.G., additional, Verhagen, H.J., additional, Verhoeven, B.A., additional, Vermeulen, C.F., additional, Vermeulen, E.G., additional, Vierhout, B.P., additional, Visser, M.J., additional, van der Vliet, J.A., additional, Vlijmen - van Keulen, C.J., additional, Voesten, H.G., additional, Voorhoeve, R., additional, Vos, A.W., additional, de Vos, B., additional, Vos, G.A., additional, Vriens, B.H., additional, Vriens, P.W., additional, de Vries, A.C., additional, de Vries, J.P., additional, de Vries, M., additional, van der Waal, C., additional, Waasdorp, E.J., additional, Wallis de Vries, B.M., additional, van Walraven, L.A., additional, van Wanroij, J.L., additional, Warlé, M.C., additional, van Weel, V., additional, van Well, A.M., additional, Welten, G.M., additional, Welten, R.J., additional, Wever, J.J., additional, Wiersema, A.M., additional, Wikkeling, O.R., additional, Willaert, W.I., additional, Wille, J., additional, Willems, M.C., additional, Willigendael, E.M., additional, Wisselink, W., additional, Witte, M.E., additional, Wittens, C.H., additional, Wolf-de Jonge, I.C., additional, Yazar, O., additional, Zeebregts, C.J., additional, van Zeeland, M.L., additional, Elshof, Jan-Willem, additional, and Willems, Martine C., additional

Published
2018
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109. Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms

Author

Schaik, T.G. van, Yeung, K.K., Verhagen, H.J., Bruin, J.L. De, Sambeek, M. van, Balm, R., Zeebregts, C.J.A., Schultze Kool, L.J., Herwaarden, J.A. van, Blankensteijn, J.D., Schaik, T.G. van, Yeung, K.K., Verhagen, H.J., Bruin, J.L. De, Sambeek, M. van, Balm, R., Zeebregts, C.J.A., Schultze Kool, L.J., Herwaarden, J.A. van, and Blankensteijn, J.D.

Abstract

Item does not contain fulltext, OBJECTIVE: Randomized trials have shown an initial survival benefit of endovascular over conventional open abdominal aortic aneurysm repair but no long-term difference up to 6 years after repair. Longer follow-up may be required to demonstrate the cumulative negative impact on survival of higher reintervention rates associated with endovascular repair. METHODS: We updated the results of the Dutch Randomized Endovascular Aneurysm Management (DREAM) trial, a multicenter, randomized controlled trial comparing open with endovascular aneurysm repair, up to 15 years of follow-up. Survival and reinterventions were analyzed on an intention-to-treat basis. Causes of death and secondary interventions were compared by use of an events per person-year analysis. RESULTS: There were 178 patients randomized to open and 173 to endovascular repair. Twelve years after randomization, the cumulative overall survival rates were 42.2% for open and 38.5% for endovascular repair, for a difference of 3.7 percentage points (95% confidence interval, -6.7 to 14.1; P = .48). The cumulative rates of freedom from reintervention were 78.9% for open repair and 62.2% for endovascular repair, for a difference of 16.7 percentage points (95% confidence interval, 5.8-27.6; P = .01). No differences were observed in causes of death. Cardiovascular and malignant disease account for the majority of deaths after prolonged follow-up. CONCLUSIONS: During 12 years of follow-up, there was no survival difference between patients who underwent open or endovascular abdominal aortic aneurysm repair, despite a continuously increasing number of reinterventions in the endovascular repair group. Endograft durability and the need for continued endograft surveillance remain key issues.

Published
2017

110. Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms

Author

Schaik, T.G (Theo) van, Yeung, K.K. (Kak), Verhagen, H.J.M. (Hence), Bruin, J.L. (J.) de, Sambeek, M.R.H.M. (Marc) van, Balm, R. (Ron), Zeebregts, C.J. (Clark), Herwaarden, J.A. (Joost) van, Blankensteijn, J.D. (Jan), Grobbee, D.E. (Diederick), Bak, A.A.A. (A. A.A.), Buth, J. (Jaap), Pattynama, P.M.T. (Peter M.T.), van Voorthuisen, A.E. (A. E.), Cuypers, P.M.W. (Philippe), Prinssen, M. (M.), Verhoeven, E.L.G. (Eric), Baas, A.F. (Annette), Hunink, M.G.M. (Myriam), Engelshoven, J.M. (Jos), Jacobs, M. (Michael), Mol, B.A.J.M. de, Bockel, J.H. van, Reekers, J.A. (Jim), Tielbeek, X., Wisselink, W. (W.), Boekema, N., Heuveling, L.M. (L. M.), Sikking, I., Prinssen, M. (Monique), Bruin, J.L. (Jorg) de, Tielbeek, A.V. (Alexander), Schaik, T.G (Theo) van, Yeung, K.K. (Kak), Verhagen, H.J.M. (Hence), Bruin, J.L. (J.) de, Sambeek, M.R.H.M. (Marc) van, Balm, R. (Ron), Zeebregts, C.J. (Clark), Herwaarden, J.A. (Joost) van, Blankensteijn, J.D. (Jan), Grobbee, D.E. (Diederick), Bak, A.A.A. (A. A.A.), Buth, J. (Jaap), Pattynama, P.M.T. (Peter M.T.), van Voorthuisen, A.E. (A. E.), Cuypers, P.M.W. (Philippe), Prinssen, M. (M.), Verhoeven, E.L.G. (Eric), Baas, A.F. (Annette), Hunink, M.G.M. (Myriam), Engelshoven, J.M. (Jos), Jacobs, M. (Michael), Mol, B.A.J.M. de, Bockel, J.H. van, Reekers, J.A. (Jim), Tielbeek, X., Wisselink, W. (W.), Boekema, N., Heuveling, L.M. (L. M.), Sikking, I., Prinssen, M. (Monique), Bruin, J.L. (Jorg) de, and Tielbeek, A.V. (Alexander)

Abstract

Objective Randomized trials have shown an initial survival benefit of endovascular over conventional open abdominal aortic aneurysm repair but no long-term difference up to 6 years after repair. Longer follow-up may be required to demonstrate the cumulative negative impact on survival of higher reintervention rates associated with endovascular repair. Methods We updated the results of the Dutch Randomized Endovascular Aneurysm Management (DREAM) trial, a multicenter, randomized controlled trial comparing open with endovascular aneurysm repair, up to 15 years of follow-up. Survival and reinterventions were analyzed on an intention-to-treat basis. Causes of death and secondary interventions were compared by use of an events per person-year analysis. Results There were 178 patients randomized to open and 173 to endovascular repair. Twelve years after randomization, the cumulative overall survival rates were 42.2% for open and 38.5% for endovascular repair, for a difference of 3.7 percentage points (95% confidence interval, −6.7 to 14.1; P =.48). The cumulative rates of freedom from reintervention were 78.9% for open repair and 62.2% for endovascular repair, for a difference of 16.7 percentage points (95% confidence interval, 5.8-27.6; P =.01). No differences were observed in causes of death. Cardiovascular and malignant disease account for the majority of deaths after prolonged follow-up. Conclusions During 12 years of follow-up, there was no survival difference between patients who underwent open or endovascular abdominal aortic aneurysm

Published
2017
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111. Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms

Author

Zorgeenheid Vaatchirurgie Medisch, UMC Utrecht, Circulatory Health, Cardiovasculaire Epi Team 9, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts-assistenten Radiotherapie, Arts-assistenten Radiologie, Onderzoek CTC, Other research (not in main researchprogram), Psychiatrie_Medisch, ZL Algemene Neurologie Medisch, Pathologie Pathologen staf, Arts-Assistenten Onderwijs Radiologie, HAG Netwerken, van Schaik, Theodorus G., Yeung, Kak K., Verhagen, Hence J., De Bruin, Jorg Lucas, van Sambeek, Marc R.H.M., Balm, Ron, Zeebregts, Clark J., van Herwaarden, Joost A., Blankensteijn, Jan D., Grobbee, D. E., Bak, Annette A A, Buth, J., Pattynama, Peter M., Verhoeven, E.L.G., Van Voorthuisen, A. E., Balm, R., Cuypers, P.W.M., Prinssen, M., van Sambeek, M.R.H.M., Baas, A. F., Hunink, M. G. Myriam, van Engelshoven, J.M., Jacobs, M. J.H.M., de Mol, Bas A J M, van Bockel, J.H., Reekers, J.A., Tielbeek, X., Wisselink, W., Boekema-Bakker, N., Heuveling, L. M., Sikking, I., van der Velden, J. J.I.M., van Loenhout, R. M.M., Rutten, M. J., Bender, M. H.M., Boomsma, J. H.B., Visser, M. J.T., de Haan, M., Smeets, H. J., DREAM trial participants, Zorgeenheid Vaatchirurgie Medisch, UMC Utrecht, Circulatory Health, Cardiovasculaire Epi Team 9, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts-assistenten Radiotherapie, Arts-assistenten Radiologie, Onderzoek CTC, Other research (not in main researchprogram), Psychiatrie_Medisch, ZL Algemene Neurologie Medisch, Pathologie Pathologen staf, Arts-Assistenten Onderwijs Radiologie, HAG Netwerken, van Schaik, Theodorus G., Yeung, Kak K., Verhagen, Hence J., De Bruin, Jorg Lucas, van Sambeek, Marc R.H.M., Balm, Ron, Zeebregts, Clark J., van Herwaarden, Joost A., Blankensteijn, Jan D., Grobbee, D. E., Bak, Annette A A, Buth, J., Pattynama, Peter M., Verhoeven, E.L.G., Van Voorthuisen, A. E., Balm, R., Cuypers, P.W.M., Prinssen, M., van Sambeek, M.R.H.M., Baas, A. F., Hunink, M. G. Myriam, van Engelshoven, J.M., Jacobs, M. J.H.M., de Mol, Bas A J M, van Bockel, J.H., Reekers, J.A., Tielbeek, X., Wisselink, W., Boekema-Bakker, N., Heuveling, L. M., Sikking, I., van der Velden, J. J.I.M., van Loenhout, R. M.M., Rutten, M. J., Bender, M. H.M., Boomsma, J. H.B., Visser, M. J.T., de Haan, M., Smeets, H. J., and DREAM trial participants

Published
2017

115. Predicting reinterventions after open and endovascular aneurysm repair using the St George's Vascular Institute score

Author

De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., Vermassen, F. E G, De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., and Vermassen, F. E G

Published
2016

116. Predicting reinterventions after open and endovascular aneurysm repair using the St George's Vascular Institute score

Author

Cardiovasculaire Epi Team 9, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts Assistenten CTC, Psychiatrie_Medisch, Pathologie Pathologen staf, Arts-assistenten Radiologie, PCR MN, Other research (not in main researchprogram), JC Overig onderzoek, De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., Vermassen, F. E G, Cardiovasculaire Epi Team 9, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts Assistenten CTC, Psychiatrie_Medisch, Pathologie Pathologen staf, Arts-assistenten Radiologie, PCR MN, Other research (not in main researchprogram), JC Overig onderzoek, De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., and Vermassen, F. E G

Published
2016

117. Quality of Life after Endovascular and Open AAA Repair. Results of a Randomised Triala

Author

Prinssen, M., Buskens, E., Blankensteijn, Jan D., Buth, J., Tielbeek, A. V., Verhoeven, E. L.G., Prins, T., Hamming, J. F., Lampmann, L. E.H., Schurink, G. W.H., de Haan, M., Balm, R., Reekers, J. A., Bender, M. H.M., Pasmans, H., Visser, M. J.T., van der Linden, E., Blankensteijn, J. D., de Smet, A. A.E.A., Vroegindeweij, D., van Sterkenburg, S. M.M., ten Haken, G. B., Boomsma, J. B.B., van Dop, H. R., de Mol van Otterloo, J. C.A., de Rooij, T. P.W., van Sambreek, M. R.H.M., Pattynama, P., Bruijninckx, C. M.A., van Overhagen, H., van der Ham, A. C., van der Velden, J. J.I.M., Wisselink, W., van den Berg, F. G., Tutein Nolthenius, R. P., Hendriksz, T. R., Vahl, A. C., de Vries, C., Mackaay, A. J.C., Smeets, H. J., van Dortmont, L. M.C., Elsman, B. H.P., Smits, T. M., van Loenhout, R. M.M., Rutten, M. J., Teijink, J. A.W., Odink, H. F., Yilmaz, E. N., den Butter, G., Poniewierski, J., Vermassen, F. E.G., Stabel, P., van Elst, F., Epidemiology and Data Science, Pathology, Surgery, ACS - Atherosclerosis & ischemic syndromes, and Radiology and nuclear medicine

Subjects
Male, Quality of life, medicine.medical_specialty, Time Factors, Health Status, Population, law.invention, Aortic aneurysm, Aneurysm, Randomized controlled trial, law, Surveys and Questionnaires, medicine, Humans, EVAR, Postoperative Period, education, Heart, lung and circulation [UMCN 2.1], Aged, Medicine(all), education.field_of_study, business.industry, Open AAA repair, Recovery of Function, medicine.disease, Abdominal aortic aneurysm, humanities, Surgery, Clinical trial, Randomised trail, Female, Cardiology and Cardiovascular Medicine, business, Vascular Surgical Procedures, Abdominal surgery, Aortic Aneurysm, Abdominal, DREAM-trial
Abstract

Contains fulltext : 57956.pdf (Publisher’s version ) (Closed access) AIM: To compare the quality of life (QoL) in the first postoperative year after elective endovascular abdominal aortic aneurysm repair (EVAR) and open repair (OR) in a randomised study. METHODS: In the Dutch Randomised Endovascular Aneurysm Management (DREAM) trial, patients are randomly allocated to EVAR or OR. QoL questionnaires (SF-36 and EuroQoL-5D) were sent to all patients preoperatively (PREOP) and at five time points in the first postoperative year (3W, 6W, 3M, 6M and 12M). Between November 1999 and August 2002, 153 patients (141 male; 12 female) were randomised (78 EVAR and 75 OR; one crossover from OR to EVAR). The EuroQoL-5D scores and the eight domains of the SF-36 for the two groups were compared using the Mann-Whitney test. Changes over time were analysed using the Wilcoxon sign test. RESULTS: There were no statistically significant differences in baseline characteristics (age, gender and SVS risk factors). The preoperative QoL scores of the study group were similar to the QoL scores of the general population of the same age. After 3W the OR group showed a significant decrease on the EuroQol-5D (p=0.022) and in six of the eight SF-36 domains. The EVAR group also showed a significant decrease on the EuroQol-5D (p=0.004) and in 5 of the 8 domains of the SF-36. At 6W the EuroQol-5D had recovered to baseline in the OR group and the decreased domains of the SF-36 had partially recovered. In the EVAR group the EuroQol-5D and three of the five decreased SF-36 domains, had returned to baseline. From 6M on, the OR group reported a significantly higher score on the EuroQoL-5D than the EVAR group (p=0.045 (6M) and p=0.001 (12M)). CONCLUSION: In the early postoperative period there is a small, yet significant QoL advantage for EVAR compared to OR. At 6 months and beyond, patients reported better QoL after OR than after EVAR.

Published
2004
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121. Predicting reinterventions after open and endovascular aneurysm repair using the St George's Vascular Institute score

Author

de Bruin, Jorg Lucas, primary, Karthikesalingam, Alan, additional, Holt, Peter J., additional, Prinssen, Monique, additional, Thompson, Matt M., additional, Blankensteijn, Jan D., additional, Grobbee, D.E., additional, Blankensteijn, J.D., additional, Bak, A.A.A., additional, Buth, J., additional, Pattynama, P.M., additional, Verhoeven, E.L.G., additional, van Voorthuisen, A.E., additional, Balm, R., additional, Cuypers, P.W.M., additional, Prinssen, M., additional, van Sambeek, M.R.H.M., additional, Baas, A.F., additional, Hunink, M.G., additional, van Engelshoven, J.M., additional, Jacobs, M.J.H.M., additional, de Mol, B.A.J.M., additional, van Bockel, J.H., additional, Reekers, J., additional, Tielbeek, X., additional, Wisselink, W., additional, Boekema, N., additional, Heuveling, L.M., additional, Sikking, I., additional, de Bruin, J.L., additional, Tielbeek, A.V., additional, Reekers, J.A., additional, Pattynama, P., additional, Prins, T., additional, van der Ham, A.C., additional, van der Velden, J.J.I.M., additional, van Sterkenburg, S.M.M., additional, ten Haken, G.B., additional, Bruijninckx, C.M.A., additional, van Overhagen, H., additional, Tutein Nolthenius, R.P., additional, Hendriksz, T.R., additional, Teijink, J.A.W., additional, Odink, H.F., additional, de Smet, A.A.E.A., additional, Vroegindeweij, D., additional, van Loenhout, R.M.M., additional, Rutten, M.J., additional, Hamming, J.F., additional, Lampmann, L.E.H., additional, Bender, M.H.M., additional, Pasmans, H., additional, Vahl, A.C., additional, de Vries, C., additional, Mackaay, A.J.C., additional, van Dortmont, L.M.C., additional, van der Vliet, A.J., additional, Schultze Kool, L.J., additional, Boomsma, J.H.B., additional, van, H.R., additional, de Mol van Otterloo, J.C.A., additional, de Rooij, T.P.W., additional, Smits, T.M., additional, Yilmaz, E.N., additional, van den Berg, F.G., additional, Visser, M.J.T., additional, van der Linden, E., additional, Schurink, G.W.H., additional, de Haan, M., additional, Smeets, H.J., additional, Stabel, P., additional, van Elst, F., additional, Poniewierski, J., additional, and Vermassen, F.E.G., additional

Published
2016
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122. Biodegradable polymer scaffold, semi-solid solder, and single-spot lasing for increasing solder-tissue bonding in suture-free laser-assisted vascular repair

Author

Pabittei, D.R., Heger, M., Simonet, M., Tuijl, van, S., Wal, van der, A.C., Beek, J.F., Balm, R., Mol, de, B.A.J.M., Cardiovascular Biomechanics, and Soft Tissue Biomech. & Tissue Eng.

Abstract

We recently showed the fortifying effect of poly-caprolactone (PCL) scaffold in liquid solder-mediated laser-assisted vascular repair (ssLAVR) of porcine carotid arteries, yielding a mean¿±¿SD leaking point pressure of 488¿±¿111¿mmHg. Despite supraphysiological pressures, the frequency of adhesive failures was indicative of weak bonding at the solder-tissue interface. As a result, this study aimed to improve adhesive bonding by using a semi-solid solder and single-spot vs. scanning irradiation. In the first experiment, in vitro ssLAVR (n¿=¿30) was performed on porcine abdominal aorta strips using a PCL scaffold with a liquid or semi-solid solder and a 670-nm diode laser for dual-pass scanning. In the second experiment, the scanning method was compared to single-spot lasing. The third experiment investigated the stability of the welds following hydration under quasi-physiological conditions. The welding strength was defined by acute breaking strength (BS). Solder-tissue bonding was examined by scanning electron microscopy and histological analysis was performed for thermal damage analysis. Altering solder viscosity from liquid to semi-solid solder increased the BS from 78¿±¿22¿N/cm2 to 131¿±¿38¿N/cm2. Compared to scanning ssLAVR, single-spot lasing improved adhesive bonding to a BS of 257¿±¿62¿N/cm2 and showed fewer structural defects at the solder-tissue interface but more pronounced thermal damage. The improvement in adhesive bonding was associated with constantly stronger welds during two weeks of hydration. Semi-solid solder and single-spot lasing increased welding strength by reducing solder leakage and improving adhesive bonding, respectively. The improvement in adhesive bonding was associated with enhanced weld stability during hydration.

Published
2012

127. Anatomic factors associated with acute endograft collapse after Gore TAG treatment of thoracic aortic dissection or traumatic rupture

Author

Muhs, B.E., Balm, R., White, G.H., and Verhagen, H.J.M.

Subjects
cardiovascular system
Abstract

OBJECTIVE: The potentially devastating complication of total or near total thoracic endoprosthesis collapse has been described with the TAG device (W. L. Gore & Associates, Flagstaff, Ariz). This rare complication has resulted in a warning to clinicians and speculation about the etiology of this problem. This report evaluates potential causative anatomic factors that may increase the probability of endoprosthesis collapse in patients undergoing endovascular thoracic aneurysm repair (TEVAR). METHODS: Preoperative and postoperative computed tomography scans were collected worldwide representing six patients who had experienced radiologically confirmed TAG endoprosthesis collapse. These were compared with a matched cohort of five patients with a TAG endoprosthesis in the same anatomic position in which no collapse occurred. Anatomic variables of aortic arch angulation, apposition, intraluminal lip length, proximal aortic diameter, distal aortic diameter, intragraft aortic diameter, percentage of oversizing, and angle of the proximal endograft to the aortic arch were compared between groups. Differences between groups were determined using the Student t test, with P

Published
2007

128. Perifere arteriën

Author

Balm, R., Legemate, D. A., Gooszen, H. G., Aronson, D. C., Blankensteijn, J. D., Gouma, D. J., Kroon, B. B. R., Lange, J. F., van Vugt, A. B., Amsterdam Cardiovascular Sciences, and Surgery

Published
2006

129. Traumatic aortic ruptures

Author

Balm, R., Hoornweg, L. L., Amsterdam Cardiovascular Sciences, and Surgery

Subjects
surgical procedures, operative
Abstract

Most patients with a traumatic aortic rupture (TAR) were involved in high velocity motor vehicle accidents. initial management of these patients should be according to the guidelines of the advanced trauma life support group (ATLS). Patients with a suspected TAR are preferably managed by controlled hypotension. TAR can be diagnosed by spiral CT angiography, additional angiography is not needed. Although results from conventional surgery have improved over the years, results from endovascular grafting are better with reduced mortality and paraplegia rates. Acute open surgery has become the second choice and patients are preferably managed by endovascular treatment. The endovascular graft can be placed with a minimal invasive procedure and delay in treatment because of accompanying injuries is avoided. Patients with a TAR treated by an endovascular graft should be kept under surveillance. For optimal patient care level I trauma centers should have thoracic endovascular grafts available for direct use

Published
2005

135. Optimization of Suture-Free Laser-Assisted Vessel Repair by Solder-Doped Electrospun Poly(e-caprolactone) Scaffold

Author

Pabittei, D.R., Heger, M., Beek, J.F., Tuijl, van, S., Simonet, M., Wal, van der, A.C., Mol, de, B.A.J.M., Balm, R., Pabittei, D.R., Heger, M., Beek, J.F., Tuijl, van, S., Simonet, M., Wal, van der, A.C., Mol, de, B.A.J.M., and Balm, R.

Abstract

Poor welding strength constitutes an obstacle in the clinical employment of laser-assisted vascular repair (LAVR) and anastomosis. We therefore investigated the feasibility of using electrospun poly(e-caprolactone) (PCL) scaffold as reinforcement material in LAVR of medium-sized vessels. In vitro solder-doped scaffold LAVR (ssLAVR) was performed on porcine carotid arteries or abdominal aortas using a 670-nm diode laser, a solder composed of 50% bovine serum albumin and 0.5% methylene blue, and electrospun PCL scaffolds. The correlation between leaking point pressures (LPPs) and arterial diameter, the extent of thermal damage, structural and mechanical alterations of the scaffold following ssLAVR, and the weak point were investigated. A strong negative correlation existed between LPP and vessel diameter, albeit LPP (484 ± 111 mmHg) remained well above pathophysiological pressures. Histological analysis revealed that thermal damage extended into the medial layer with a well-preserved internal elastic lamina and endothelial cells. Laser irradiation of PCL fibers and coagulation of solder material resulted in a strong and stiff scaffold. The weak point of the ssLAVR modality was predominantly characterized by cohesive failure. In conclusion, ssLAVR produced supraphysiological LPPs and limited tissue damage. Despite heat-induced structural/mechanical alterations of the scaffold, PCL is a suitable polymer for weld reinforcement in medium-sized vessel ssLAVR.

Published
2011

136. Long-term outcome of open or endovascular repair of abdominal aortic aneurysm

Author

Bruin, J.L. (Jorg) de, Baas, A.F. (Annette), Buth, J. (Jaap), Prinssen, M. (Monique), Verhoeven, E.L.G. (Eric), Cuypers, P.M.W. (Philippe), Sambeek, M.R.H.M. (Marc) van, Balm, R. (Ron), Grobbee, D.E. (Diederick), Blankensteijn, J.D. (Jan), Bruin, J.L. (Jorg) de, Baas, A.F. (Annette), Buth, J. (Jaap), Prinssen, M. (Monique), Verhoeven, E.L.G. (Eric), Cuypers, P.M.W. (Philippe), Sambeek, M.R.H.M. (Marc) van, Balm, R. (Ron), Grobbee, D.E. (Diederick), and Blankensteijn, J.D. (Jan)

Abstract

BACKGROUND: For patients with large abdominal aortic aneurysms, randomized trials have shown an initial overall survival benefit for elective endovascular repair over conventional open repair. This survival difference, however, was no longer significant in the second year after the procedure. Information regarding the comparative outcome more than 2 years after surgery is important for clinical decision making. METHODS: We conducted a long-term, multicenter, randomized, controlled trial comparing open repair with endovascular repair in 351 patients with an abdominal aortic aneurysm of at least 5 cm in diameter who were considered suitable candidates for both techniques. The primary outcomes were rates of death from any cause and reintervention. Survival was calculated with the use of Kaplan-Meier methods on an intentionto-treat basis. RESULTS: We randomly assigned 178 patients to undergo open repair and 173 to undergo endovascular repair. Six years after randomization, the cumulative survival rates were 69.9% for open repair and 68.9% for endovascular repair (difference, 1.0 percentage point; 95% confidence interval [CI], -8.8 to 10.8; P=0.97). The cumulative rates of freedom from secondary interventions were 81.9% for open repair and 70.4% for endovasc

Published
2010
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137. Long-term outcome of open or endovascular repair of abdominal aortic aneurysm.

Author

Bruin, J.L. De, Baas, A.F., Buth, J., Prinssen, M., Verhoeven, E.L., Cuypers, P.W., Sambeek, M.R. van, Balm, R., Grobbee, D.E., Blankensteijn, J.D., Bruin, J.L. De, Baas, A.F., Buth, J., Prinssen, M., Verhoeven, E.L., Cuypers, P.W., Sambeek, M.R. van, Balm, R., Grobbee, D.E., and Blankensteijn, J.D.

Abstract

Contains fulltext : 87282.pdf (publisher's version ) (Open Access), BACKGROUND: For patients with large abdominal aortic aneurysms, randomized trials have shown an initial overall survival benefit for elective endovascular repair over conventional open repair. This survival difference, however, was no longer significant in the second year after the procedure. Information regarding the comparative outcome more than 2 years after surgery is important for clinical decision making. METHODS: We conducted a long-term, multicenter, randomized, controlled trial comparing open repair with endovascular repair in 351 patients with an abdominal aortic aneurysm of at least 5 cm in diameter who were considered suitable candidates for both techniques. The primary outcomes were rates of death from any cause and reintervention. Survival was calculated with the use of Kaplan-Meier methods on an intention-to-treat basis. RESULTS: We randomly assigned 178 patients to undergo open repair and 173 to undergo endovascular repair. Six years after randomization, the cumulative survival rates were 69.9% for open repair and 68.9% for endovascular repair (difference, 1.0 percentage point; 95% confidence interval [CI], -8.8 to 10.8; P=0.97). The cumulative rates of freedom from secondary interventions were 81.9% for open repair and 70.4% for endovascular repair (difference, 11.5 percentage points; 95% CI, 2.0 to 21.0; P=0.03). CONCLUSIONS: Six years after randomization, endovascular and open repair of abdominal aortic aneurysm resulted in similar rates of survival. The rate of secondary interventions was significantly higher for endovascular repair. (ClinicalTrials.gov number, NCT00421330.)

Published
2010

138. Reduced renal failure following thoracoabdominal aortic aneurysm repair by selective perfusion

Author

Jacobs, M. J., Eijsman, L., Meylaerts, S. A., Balm, R., Legemate, D. A., de Haan, P., Kalkman, C. J., de Mol, B. A., and Other departments

Abstract

OBJECTIVES: Renal failure and visceral ischemia are feared complications following thoracoabdominal aortic aneurysm (TAAA) repair, significantly contributing to mortality. This prospective study describes volume- and pressure-controlled perfusion of the renal and visceral arteries during TAAA surgery. METHODS: In 73 consecutive patients (mean age 59 years), TAAA repair (27 type I, 28 type II, 8 type III and 10 type IV) was performed, using retrograde and selective organ perfusion. Sixteen patients had impaired renal function with blood creatinine higher than 100 mmol/l. During the thoracic part of the procedure, the mean distal aortic pressure was kept above 60 mm Hg by means of left-heart bypass. After opening the abdominal aorta, the renal and visceral arteries were individually perfused by means of perfusion catheters (9 French) in the first 33 patients (group I). Volume flow through each catheter was assessed with ultrasound flow meters and maintained at least at 60 ml/min. In addition to volume flow measurements, catheters with pressure sensors were used in the last 40 patients (group II), allowing pressure-controlled selective perfusion. The extent of the aneurysm was comparable in both groups. RESULTS: Mean cross-clamp time for the thoracic part was 46 min, including proximal anastomosis and reattachment of intercostal arteries. Mean cross-clamp time for the abdominal part was 74 min, including re-implantation of intestinal and renal arteries and selective dacron grafts to the celiac-axis arteries (n = 5), superior mesenteric arteries (n = 8) and renal arteries (n = 25), through which the catheters guaranteed continuous perfusion during the time the anastomosis was performed. Urine output was uninterrupted in all patients, irrespective of cross-clamp time. In group I, one patient (3%) developed renal failure and three patients (9%) required temporary peritoneal dialysis. In group II, no patients developed renal failure and two patients (5%) required temporary peritoneal dialysis. Thirteen patients with pre-existing renal impairment did not deteriorate. No patients developed visceral ischemia or multiple-organ failure. Total in-hospital mortality was 6/73 (8%) and was related to cardiopulmonary complications. CONCLUSIONS: Renal and visceral ischemia can be reduced significantly by continuous perfusion during cross-clamping in TAAA repair. Not only sufficient volume flow but also adequate arterial pressure appears to be essential in maintaining renal function

Published
1998

142. Quality of life from a randomized trial of open and endovascular repair for abdominal aortic aneurysm.

Author

de Bruin, J. L., Groenwold, R. H. H., Baas, A. F., Brownrigg, J. R., Prinssen, M., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A. A., Buth, J., Pattynama, P. M., Verhoeven, E. L. G., van Voorthuisen, A. E., Balm, R., Cuypers, P. W. M., van Sambeek, M. R. H. M., G Verhoeven, E. L., Hunink, M. G., van Engelshoven, J. M., Jacobs, M. J. H. M., and de Mol, B. A. J. M

Subjects
AORTIC aneurysm treatment, ABDOMINAL aorta surgery, ENDOVASCULAR surgery, QUALITY of life, FOLLOW-up studies (Medicine)
Abstract

Background Long-term survival is similar after open or endovascular repair of abdominal aortic aneurysm. Few data exist on the effect of either procedure on long-term health-related quality of life ( HRQoL) and health status. Methods Patients enrolled in a multicentre randomized clinical trial ( DREAM trial; 2000-2003) in Europe of open repair versus endovascular repair ( EVAR) of abdominal aortic aneurysm were asked to complete questionnaires on health status and HRQoL. HRQoL scores were assessed at baseline and at 13 time points thereafter, using generic tools, the Medical Outcomes Study 36-Item Short-Form Health Survey ( SF-36®) and EuroQol 5D ( EQ-5D™). Physical ( PCS) and mental component summary scores were also calculated. Follow-up was 5 years. Results Some 332 of 351 patients enrolled in the trial returned questionnaires. More than 70 per cent of questionnaires were returned at each time point. Both surgical interventions had a short-term negative effect on HRQoL and health status. This was less severe in the EVAR group than in the open repair group. In the longer term the physical domains of SF-36® favoured open repair: mean difference in PCS score between open repair and EVAR −1·98 (95 per cent c.i. −3·56 to −0·41). EQ-5D™ descriptive and EQ-5D™ visual analogue scale scores for open repair were also superior to those for EVAR after the initial 6-week interval: mean difference −0·06 (−0·10 to −0·02) and −4·09 (−6·91 to −1·27) respectively. Conclusion In this study EVAR appeared to be associated with less severe disruption to HRQoL and health status in the short term. However, during longer-term follow-up to 5 years, patients receiving open repair appeared to have improved quality of life and health status. [ABSTRACT FROM AUTHOR]

Published
2016
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144. The risk of withdrawing chronic anticoagulation because of acute GI bleeding

Author

Kuwada, S. K., Balm, R., Gostout, C. J., and Other departments

Abstract

OBJECTIVE: We sought evidence for thromboembolic sequelae after the transient withdrawal of chronic anti-coagulation because of acute GI bleeding. METHODS: Our Gastrointestinal Bleeding Team endoscopic database was reviewed over a 5-yr period to identify patients who underwent a transient withdrawal from chronic anticoagulation as a result of acute GI bleeding. Long term follow-up records were available for all study patients and were carefully scrutinized for any symptomatic thromboembolic events. RESULTS: Twenty-seven patients were included in the study, of which 17 (63%) were on chronic anticoagulation for prosthetic heart valves. Chronic anticoagulation was withheld for a median period of 3 days (range = 2-7 days) for patients with prosthetic heart valves and 7 days (range = 2-15 days) for patients on chronic anticoagulation for other indications. Over a median follow-up period of 8 months (range = 1-54 months), one patient developed documented lower extremity thromboembolism. CONCLUSIONS: We conclude that symptomatic thromboembolism can occur after the transient withdrawal of chronic anticoagulation for acute GI bleeding but that it does not occur frequently

Published
1996

145. A randomized trial comparing conventional and endovascular repair of abdominal aortic aneurysms.

Author

Prinssen, M., Verhoeven, E.L., Buth, J., Cuypers, P.W., Sambeek, M.R. van, Balm, R., Buskens, E., Grobbee, D.E., Blankensteijn, J.D., Prinssen, M., Verhoeven, E.L., Buth, J., Cuypers, P.W., Sambeek, M.R. van, Balm, R., Buskens, E., Grobbee, D.E., and Blankensteijn, J.D.

Abstract

Contains fulltext : 57421.pdf (publisher's version ) (Open Access), BACKGROUND: Although the initial results of endovascular repair of abdominal aortic aneurysms were promising, current evidence from controlled studies does not convincingly show a reduction in 30-day mortality relative to that achieved with open repair. METHODS: We conducted a multicenter, randomized trial comparing open repair with endovascular repair in 345 patients who had received a diagnosis of abdominal aortic aneurysm of at least 5 cm in diameter and who were considered suitable candidates for both techniques. The outcome events analyzed were operative (30-day) mortality and two composite end points of operative mortality and severe complications and operative mortality and moderate or severe complications. RESULTS: The operative mortality rate was 4.6 percent in the open-repair group (8 of 174 patients; 95 percent confidence interval, 2.0 to 8.9 percent) and 1.2 percent in the endovascular-repair group (2 of 171 patients; 95 percent confidence interval, 0.1 to 4.2 percent), resulting in a risk ratio of 3.9 (95 percent confidence interval, 0.9 to 32.9). The combined rate of operative mortality and severe complications was 9.8 percent in the open-repair group (17 of 174 patients; 95 percent confidence interval, 5.8 to 15.2 percent) and 4.7 percent in the endovascular-repair group (8 of 171 patients; 95 percent confidence interval, 2.0 to 9.0 percent), resulting in a risk ratio of 2.1 (95 percent confidence interval, 0.9 to 5.4). CONCLUSIONS: On the basis of the overall results of this trial, endovascular repair is preferable to open repair in patients who have an abdominal aortic aneurysm that is at least 5 cm in diameter. Long-term follow-up is needed to determine whether this advantage is sustained.

Published
2004

146. A randomized trial comparing conventional and endovascular repair of abdominal aortic aneurysms.

Author

JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Zorgeenheid Vaatchirurgie Medisch, Healthcare Innovation & Evaluation, Epidemiology & Health Economics, Prinssen, M., Verhoeven, EL, Buth, J., Cuypers, PW, van Sambeek, M.R.H.M., Balm, R., Buskens, E., Grobbee, D.E., Blankensteijn, J.D., JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Zorgeenheid Vaatchirurgie Medisch, Healthcare Innovation & Evaluation, Epidemiology & Health Economics, Prinssen, M., Verhoeven, EL, Buth, J., Cuypers, PW, van Sambeek, M.R.H.M., Balm, R., Buskens, E., Grobbee, D.E., and Blankensteijn, J.D.

Published
2004

147. Behandeling van een infrarenaal aorta-aneurysma door middel van een transfemoraal ingebrachte endoprothese: eerste ervaringen bij 9 patiënten in Nederland

Author

Balm, R., Eikelboom, B. C., de Smet, A. M., Mali, W. P., and Other departments

Subjects
cardiovascular system
Abstract

OBJECTIVE: To describe the first experiences with transfemoral aortic endoprostheses for treatment of aortic aneurysms in the Netherlands. SETTING: University Hospital Utrecht, The Netherlands. METHOD: Patient selection was based on information presented on CT and angiography films. Only patients with an asymptomatic aneurysm and non-dilated aortic segments both distal from the renal arteries and proximal to the aortic bifurcation were selected. Of 71 patients screened only nine candidates were selected. RESULTS: The placement of the endoprosthesis was initially successful in all patients. The duration of the operation varied from 60 to 160 min. An intimal lesion of the common femoral artery occurred in one patient. In three cases leakage of contrast material outside the prosthesis but inside the aneurysm was seen on the postoperative CT angiogram. In one patient the endoprosthesis had to be replaced by a conventional aortic tube graft on the second postoperative day. After the procedure the patients stayed in hospital for another 3 to 20 days (median: 5). CONCLUSION: Endovascular treatment of infrarenal abdominal aneurysm is a promising technique. The main advantages to the patient are that laparotomy is not necessary and that the hospital stay is reduced

Published
1995

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