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111 results on '"B. C. Liu"'

101. Crack tip parameters and elastic-plastic fracture of metals

Author

Fu-Pen Chiang and B. C. Liu

Subjects
Crack closure, Fracture toughness, Materials science, mental disorders, Fracture (geology), Crack tip opening displacement, Fracture mechanics, Strain hardening exponent, Composite material, Critical value, Crack growth resistance curve
Abstract

By using optical displacement-measuring techniques we obtain the crack tip fields in terms of crack tip strain, crack opening angle (COA) and crack tip opening angle (CTOA). Thin plates with different crack configurations made of six elastic-plastic materials with strain hardening exponent ranging from 3 to ∞ are studied. We find that the COA resistance curve assumes certain characteristics common to all the materials. The experimental results indicate that the critical value of COA may be used as a fracture toughness parameter for these materials.

Published
1990

102. Analysis and comparison of cache coherence protocols for a packet-switched multiprocessor

Author

Qing Yang, Laxmi N. Bhuyan, and B.-C. Liu

Subjects
Queueing theory, Hardware_MEMORYSTRUCTURES, Basis (linear algebra), Computer science, business.industry, Multiprocessing, Parallel computing, Theoretical Computer Science, Packet switching, Computational Theory and Mathematics, Hardware and Architecture, Write-once, Mean value analysis, Cache, business, Software, Cache coherence, Computer network
Abstract

Analytical models are developed for seven existing cache protocols, namely, Write-Once, Write-Through, Synapse, Berkeley, Illinois, Firefly, and Dragon. The protocols are implemented on a multiprocessor with a packet-switched shared bus. The models are based on queuing networks that consist of both open and closed classes of customers. The models incorporate the requests for invalidation signals, write-through, and write-back operations, and the solution is based on the mean value analysis (MVA) algorithm. The performance of these protocols under various system parameters is compared on the basis of the models. It is found that Firefly and Dragon perform better than the others. >

Published
1989

104. Optical Analysis Of HRR Field

Author

T. V. Hareesh, Fu-Pen Chiang, B. C. Liu, and S. Li

Subjects
Physics, Deformation (mechanics), Field (physics), business.industry, Fissure, General Engineering, Boundary (topology), Fracture mechanics, Work hardening, Mechanics, Atomic and Molecular Physics, and Optics, Optics, medicine.anatomical_structure, medicine, Limit (mathematics), business, Plane stress
Abstract

This paper examines the experimental u1, u2, and u3 displacements obtained in the vicinity of a plastically deformed crack tip in different work hardening materials in the background of the Hutchinson-Rice-Rosengren (HRR) field equations. It is shown that the two-dimensional plane stress solution breaks down in the immediate vicinity of the crack tip because of the three-dimensional nature of the deformations due to finite plate thickness. This "inner limit" seems to vary from 0.75 to 1.5 times the thickness with directional dependence. Some light is also shed on the "outer limit" of HRR equations, beyond which the theory ceases to be valid under the influence of the surrounding elastic field or the physical boundary of the plate or a combination of both.

Published
1988

107. Precision measurement of the D*(0) decay branching fractions

Author

Kai Liu, Z. Wu, K. Li, Fang Liu, Lei Zhou, S. Zhu, D. H. Zhang, K. L. He, J. F. Chang, M. Tiemens, H. B. Liu, J. Q. Zhang, Z. Jiao, C. L. Luo, X. L. Ji, Bibo Ke, M. N. Achasov, Giulietto Felici, H. M. Hu, J. P. Dai, G. Chen, I. Uman, Q. J. Xu, M. Ullrich, J. V. Bennett, C. X. Liu, D. J. Ambrose, M. L. Chen, N. Yu. Muchnoi, A. Q. Guo, X. Y. Shen, Y. Xia, Xiaocong Ai, D. Bettoni, H. S. Chen, X. L. Li, Andrzej Kupsc, W. L. Yuan, Y. J. Mo, X. R. Chen, H. Loehner, B. Spruck, H. H. Liu, M. Albrecht, Y. Ding, X. Y. Zhou, R. Baldini Ferroli, J. C. Li, Z. P. Zhang, P. R. Li, Z. Haddadi, F. Feldbauer, L. Yang, J. L. Zhang, F. F. An, T. Weber, A. Zallo, I. Denysenko, S. Ma, Z. P. Mao, F. Li, D. Toth, Magnus Wolke, B. X. Yu, Q. P. Ji, J. F. Hu, J. L. Ping, M. Lv, X. N. Ma, D. P. Jin, L. S. Wang, Y. Zeng, I. Garzia, Ling Zhao, W. M. Song, S. H. Zhang, S. Spataro, S. X. Du, X. N. Li, Y. T. Liang, Y. F. Wang, M. Ripka, S. P. Wen, X. C. Lou, Y. H. Yan, B. Y. Zhang, V. Santoro, M. Greco, S. Pacetti, J. G. Lu, X. T. Huang, Y. Huang, Zhiqing Liu, M. Pelizaeus, Fu-Hu Liu, C. Q. Feng, C. C. Zhang, Dayong Wang, N. Qin, A. Calcaterra, M. Maggiora, P. L. Liu, X. L. Luo, H. Y. Sheng, M. Fritsch, G. Rong, L. L. Wang, W. C. Yan, E. Boger, T. Johansson, S. J. Zhao, W. Shan, Chi Zhang, C. Dong, S. Sosio, X. D. Ruan, H. Muramatsu, Brent J. Liu, M. Kavatsyuk, J. C. Chen, Jingzhou Zhao, T. Held, M. Kornicer, Y. Q. Wang, L. Fava, Yulei Han, F. E. Maas, Qiang Zhao, S. Nisar, C. J. Tang, P. F. Duan, E. H. Thorndike, X. Fang, J. H. Zou, Xiao-Rui Lyu, Y. F. Liang, W. Kuehn, K. Goetzen, Jia-ju Zhang, I. Tapan, I. Boyko, H. P. Peng, Z. A. Liu, O. Albayrak, J. W. Zhao, B. Wang, J. F. Sun, Cheng Li, C. Hu, B. L. Wang, X. Y. Song, D. Xiao, H. L. Dai, Y. J. Sun, Jie Liu, H. X. Yang, X. S. Kang, Heng-Yun Ye, S. S. Sun, S. Marcello, J. Zhuang, Y. B. Chen, S. B. Liu, L. B. Guo, D. H. Wei, E. Fioravanti, Y. H. Zhang, X. R. Zhou, Y. P. Guo, G. S. Varner, X. Y. Zhang, W. Gradl, J. Fang, Chuan Liu, Xiaofeng Zhu, J. Z. Zhang, D. W. Bennett, Zujian Wang, T. C. Zhao, L. Yan, P. L. Wang, H. W. Yu, H. H. Zhang, Z. Y. Wang, X. Tang, Yaquan Fang, L. H. Wu, K. J. Zhu, Xuantong Zhang, W. B. Yan, R. G. Ping, O. Bondarenko, G. S. Huang, X. Y. Ma, Y. K. Heng, S. S. Fang, Z. J. Sun, G. F. Xu, X. F. Wang, X. M. Li, K. Zhang, S. Han, Y. Gao, X. P. Xu, M. Qi, F. A. Harris, K. Schoenning, P. X. Shen, A. A. Zafar, M. H. Gu, Y. H. Guan, Zhigang Wang, M. Bertani, W. P. Wang, F. Bianchi, M. Savrie, Y. Guo, Q. A. Malik, Q. M. Ma, Z. H. Qin, Zhiqiang Liu, Y. B. Zhao, L. W. Jiang, R. Q. Lu, L. Q. Qin, J. F. Qiu, W. D. Li, H. J. Lu, T. Ma, W. X. Gong, Q. Liu, B. X. Zhang, Z. Y. He, K. Peters, X. Cai, A. Yuncu, H. P. Cheng, Tao Li, F. C. Ma, Q. Gao, Zhiqing Zhang, Yuehong Xie, B. S. Zou, T. Luo, Li Zhou, J. Z. Fan, A. Zhemchugov, C. F. Redmer, Yang Yang, A. Denig, D. Y. Wang, T. Hu, P. Patteri, X. S. Qin, H. Liang, Xiao-Hai Liu, I. B. Nikolaev, M. Ablikim, G. X. Sun, H. P. Huang, L. G. Xia, Z. A. Zhu, Jianhao Zhang, Sai-Juan Chen, M. Ye, Z. G. Zhao, F. Nerling, Yi-Ming Hu, S. Schumann, B. Zhong, J. P. Liu, O. B. Kolcu, J. G. Messchendorp, C. P. Shen, Y. B. Liu, H. L. Ma, Qiunan Xu, G. R. Liao, D. Dedovich, Y. Yuan, Y. X. Yang, R. Kliemt, J. Z. Bai, R. E. Mitchell, M. R. Shepherd, K. Wang, G. Cibinetto, Jie Yu, M. Y. Dong, Z. L. Hou, T. J. Min, G. Zhao, Feng Liu, S. Qian, A. Hafner, Y. Z. Sun, X. Y. Niu, Xiang Zhou, Y. Ban, T. Hussain, Kejun Zhu, X. Liu, Y. H. Zheng, T. Guo, C. D. Fu, Serkant Ali Cetin, Jianmin Dong, C. Z. Yuan, B. Kopf, Z. Ning, L. L. Jiang, Q. An, X. H. Mo, J. H. Yin, K. H. Rashid, U. Wiedner, X. L. Kang, Q. W. Zhao, M. Lara, Lei Xu, N. Kalantar-Nayestanaki, P. Larin, Y. P. Lu, H. Cai, M. H. Ye, Yun-Zhi Zhang, P. Weidenkaff, L. D. Liu, O. Cakir, Jin Li, W. J. Zheng, Y. Nefedov, J. B. Jiao, Huan Ren, J. Liu, M. Destefanis, X. B. Ji, M. G. Zhao, Z. G. Wang, H. Y. Zhang, Haiwen Liu, X. K. Zhou, J. S. Lange, J. Y. Zhang, M. X. Luo, J. S. Huang, J. M. Bian, D. Cronin-Hennessy, Zhenyu Zhang, W. Lai, C. Morales Morales, Y. J. Mao, D. X. Lin, Z. J. Xiao, B. Zheng, Z. T. Sun, H. B. Li, L. Y. Dong, Y. N. Pu, G. Li, S. G. Wang, Z. Y. Deng, Jie Zhao, X. K. Chu, Y. D. Wang, M. Wang, G. M. Huang, Wei Li, Qun-Yao Wang, LiLi Zhang, J. Min, Yang Qin, M. Shao, G. Chelkov, A. Sarantsev, Lei Zhao, G. F. Cao, L. L. Ma, A. Amoroso, A. Dbeyssi, Y. T. Gu, A. Julin, F. De Mori, B. Kloss, Y. S. Zhu, J. P. Zheng, Q. Ouyang, C. X. Yu, C. F. Qiao, K. Moriya, Z. B. Li, C. H. Li, S. L. Niu, X. Q. Li, D. M. Li, S. Jin, K. Y. Liu, J. B. Wei, S. L. Olsen, R. A. Briere, R. Poling, X. S. Jiang, Y. C. Zhu, Томский государственный университет Радиофизический факультет Научные подразделения РФФ, Research unit Nuclear & Hadron Physics, Doğuş Üniversitesi, Fen Edebiyat Fakültesi, Fizik Bölümü, TR3959, Çetin, Serkant Ali, İstanbul Arel Üniversitesi, and [Ablikim, M. -- Ai, X. C. -- An, F. F. -- Bai, J. Z. -- Cai, X. -- Cao, G. F. -- Chang, J. F. -- Chen, G. -- Chen, H. S. -- Chen, J. C. -- Chen, M. L. -- Chen, X. -- Chen, Y. B. -- Dai, H. L. -- Deng, Z. Y. -- Dong, J. -- Dong, L. Y. -- Dong, M. Y. -- Duan, P. F. -- Fang, J. -- Fang, S. S. -- Fang, Y. -- Fu, C. D. -- Gao, Q. -- Gong, W. X. -- Gu, M. H. -- Guan, Y. H. -- Guo, A. Q. -- Guo, Y. -- Han, Y. L. -- He, K. L. -- Heng, Y. K. -- Hou, Z. L. -- Hu, H. M. -- Hu, T. -- Hu, Y. -- Ji, Q. -- Ji, X. B. -- Ji, X. L. -- Jiang, L. L. -- Jiang, X. S. -- Jin, D. P. -- Jin, S. -- Kang, X. L. -- Lai, W. -- Li, C. H. -- Li, F. -- Li, G. -- Li, H. B. -- Li, J. C. -- Li, W. D. -- Li, W. G. -- Li, X. N. -- Liu, B. J. -- Liu, C. X. -- Liu, Fang -- Liu, H. H. -- Liu, H. M. -- Liu, J. -- Liu, J. Y. -- Liu, P. L. -- Liu, Z. A. -- Liu, Zhiqiang -- Lou, X. C. -- Lu, J. G. -- Lu, Y. -- Lu, Y. P. -- Luo, X. L. -- Lv, M. -- Ma, H. L. -- Ma, Q. M. -- Ma, S. -- Ma, T. -- Ma, X. Y. -- Mao, Z. P. -- Min, J. -- Min, T. J. -- Mo, X. H. -- Ning, Z. -- Niu, S. L. -- Niu, X. Y. -- Ouyang, Q. -- Ping, R. G. -- Qian, S. -- Qin, X. S. -- Qin, Z. H. -- Qiu, J. F. -- Rong, G. -- Shen, X. Y. -- Sheng, H. Y. -- Song, W. M. -- Song, X. Y. -- Sun, G. X. -- Sun, S. S. -- Sun, Y. Z. -- Sun, Z. J. -- Tang, X. -- Wang, K. -- Wang, L. L. -- Wang, L. S. -- Wang, P. -- Wang, P. L. -- Wang, Q. J. -- Wang, W. -- Wang, Y. F. -- Wang, Z. -- Wang, Z. G. -- Wang, Z. Y. -- Wen, S. P. -- Wu, L. H. -- Wu, Z. -- Xiao, D. -- Xie, Y. G. -- Xu, G. F. -- Xu, L. -- Yang, H. X. -- Ye, H. -- Ye, M. -- Yin, J. H. -- Yu, B. X. -- Yuan, C. Z. -- Yuan, Y. -- Zhang, B. X. -- Zhang, B. Y. -- Zhang, C. C. -- Zhang, D. H. -- Zhang, H. Y. -- Zhang, J. J. -- Zhang, J. L. -- Zhang, J. Q. -- Zhang, J. W. -- Zhang, J. Y. -- Zhang, J. Z. -- Zhang, K. -- Zhang, L. -- Zhang, S. H. -- Zhang, X. J. -- Zhang, Y. -- Zhang, Y. H. -- Zhao, G. -- Zhao, J. W. -- Zhao, J. Y. -- Zhao, J. Z. -- Zhao, Ling -- Zhao, Q. -- Zhao, Q. W. -- Zhao, T. C. -- Zhao, Y. B. -- Zheng, J. P. -- Zhou, L. -- Zhou, X. Y. -- Zhu, K. -- Zhu, K. J. -- Zhu, S. -- Zhu, Y. S. -- Zhu, Z. A. -- Zhuang, J. -- Zou, B. S. -- Zou, J. H.] Inst High Energy Phys, Beijing 100049, Peoples R China -- [Chen, H. Y. -- Shen, C. P.] Beihang Univ, Beijing 100191, Peoples R China -- [Albrecht, M. -- Held, T. -- Kopf, B. -- Pelizaeus, M. -- Wiedner, U.] Ruhr Univ Bochum, D-44780 Bochum, Germany -- [Albayrak, O. -- Bennett, J. V. -- Briere, R. A. -- Ke, B. C. -- Liu, C. L.] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA -- [Huang, G. M. -- Liu, Feng -- Mo, Y. J. -- Yang, Y. -- Zhang, Z. H.] Cent China Normal Univ, Wuhan 430079, Peoples R China -- [Ye, M. H.] China Ctr Adv Sci & Technol, Beijing 100190, Peoples R China -- [Nisar, S.] COMSATS Inst Informat Technol, Lahore 54000, Pakistan -- [Achasov, M. N. -- Muchnoi, N. Yu. -- Nikolaev, I. B.] G I Budker Inst Nucl Phys SB RAS BINP, Novosibirsk 630090, Russia -- [Goetzen, K. -- Peters, K.] GSI Helmholtzcentre Heavy Ion Res GmbH, D-64291 Darmstadt, Germany -- [Liao, G. R. -- Wei, D. H. -- Yang, Y. X.] Guangxi Normal Univ, Guilin 541004, Peoples R China -- [Gu, Y. T. -- Li, X. M. -- Liu, H. B. -- Ruan, X. D.] Guangxi Univ, Nanning 530004, Peoples R China -- [Li, K. -- Xu, Q. J.] Hangzhou Normal Univ, Hangzhou 310036, Zhejiang, Peoples R China -- [Dbeyssi, A. -- Fritsch, M. -- Kliemt, R. -- Larin, P. -- Lin, D. X. -- Maas, F. E. -- Morales, C. Morales -- Nerling, F.] Helmholtz Inst Mainz, D-55099 Mainz, Germany -- [Huang, J. S. -- Sun, J. F.] Henan Normal Univ, Xinxiang 453007, Peoples R China -- [Liu, H. H.] Henan Univ Sci & Technol, Luoyang 471003, Peoples R China -- [Cheng, H. P. -- Jiao, Z. -- Lu, H. J.] Huangshan Coll, Huangshan 245000, Peoples R China -- [Lu, R. Q. -- Pu, Y. N. -- Xia, Y. -- Yan, Y. H. -- Zeng, Y.] Hunan Univ, Changsha 410082, Peoples R China -- [Bennett, D. W. -- Lara, M. -- Mitchell, R. E. -- Moriya, K. -- Shepherd, M. R. -- Sun, Z. T.] Indiana Univ, Bloomington, IN 47405 USA -- [Ferroli, R. Baldini -- Bertani, M. -- Calcaterra, A. -- Felici, G. -- Patteri, P. -- Wang, Y. D. -- Zallo, A.] Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy -- [Pacetti, S.] Univ Perugia, Ist Nazl Fis Nucl, I-06100 Perugia, Italy -- [Bettoni, D. -- Cibinetto, G. -- Fioravanti, E. -- Garzia, I. -- Santoro, V.] INFN Sezione Ferrara, I-44122 Ferrara, Italy -- [Savrie, M.] Univ Ferrara, I-44122 Ferrara, Italy -- [Denig, A. -- Feldbauer, F. -- Fritsch, M. -- Gradl, W. -- Guo, Y. P. -- Hafner, A. -- Kloss, B. -- Liu, Zhiqing -- Redmer, C. F. -- Ripka, M. -- Schumann, S. -- Wang, Y. Q. -- Weber, T.] Johannes Gutenberg Univ Mainz, D-55099 Mainz, Germany -- [Boger, E. -- Boyko, I. -- Chelkov, G. -- Dedovich, D. -- Denysenko, I. -- Nefedov, Y. -- Sarantsev, A. -- Zhemchugov, A.] Joint Inst Nucl Res, Dubna 141980, Russia -- [Kuehn, W. -- Lange, J. S. -- Liang, Y. T. -- Spruck, B. -- Ullrich, M.] Univ Giessen, D-52425 Giessen, Germany -- [Bondarenko, O. -- Haddadi, Z. -- Kalantar-Nayestanaki, N. -- Kavatsyuk, M. -- Loehner, H. -- Messchendorp, J. G. -- Tiemens, M.] Univ Groningen, KVI CART, NL-9747 AA Groningen, Netherlands -- [Chen, X. R. -- Liu, X. -- Yu, J. S.] Lanzhou Univ, Lanzhou 730000, Peoples R China -- [Ding, Y. -- Liu, K. Y. -- Ma, F. C.] Liaoning Univ, Shenyang 110036, Peoples R China -- [Guo, L. B. -- Guo, T. -- Hu, C. -- Luo, C. L. -- Ping, J. L. -- Xiao, Z. J. -- Zhong, B.] Nanjing Normal Univ, Nanjing 210023, Peoples R China -- [Chen, S. J. -- Huang, Y. -- Qi, M. -- Yuan, W. L. -- Zhang, C.] Nanjing Univ, Nanjing 210093, Peoples R China -- [Dong, C. -- He, Z. Y. -- Ji, Q. P. -- Kang, X. S. -- Li, X. Q. -- Liu, Y. B. -- Ma, X. N. -- Shen, P. X. -- Wang, B. -- Yu, C. X. -- Zhao, M. G. -- Zhou, Li] Nankai Univ, Tianjin 300071, Peoples R China -- [Ban, Y. -- Chu, X. K. -- Liu, L. D. -- Mao, Y. J. -- Qin, Y. -- Shan, W. -- Wang, D. -- Wang, D. Y. -- Wang, S. G. -- Wei, J. B. -- Yu, H. W.] Peking Univ, Beijing 100871, Peoples R China -- [Li, Jin -- Olsen, S. L.] Seoul Natl Univ, Seoul 151747, South Korea -- [Huang, X. T. -- Jiao, J. B. -- Li, K. -- Li, T. -- Li, X. L. -- Ma, L. L. -- Qin, L. Q. -- Wang, M. -- Zhang, X. Y. -- Zheng, W. J.] Shandong Univ, Jinan 250100, Peoples R China -- [Dai, J. P.] Shanghai Jiao Tong Univ, Shanghai 200240, Peoples R China -- [Liu, F. H.] Shanxi Univ, Taiyuan 030006, Peoples R China -- [Liang, Y. F. -- Tang, C. J.] Sichuan Univ, Chengdu 610064, Peoples R China -- [Xu, X. P.] Soochow Univ, Suzhou 215006, Peoples R China -- [Li, Z. B. -- Zhang, H. H.] Sun Yat Sen Univ, Guangzhou 510275, Peoples R China -- [Fan, J. Z. -- Gao, Y. -- Liu, K. -- Wang, X. F. -- Xia, L. G. -- Zhu, X. L.] Tsinghua Univ, Beijing 100084, Peoples R China -- [Cakir, O.] Istanbul Aydin Univ, TR-34295 Istanbul, Turkey -- [Cetin, S. A. -- Kolcu, O. B. -- Uman, I. -- Yuncu, A.] Dogus Univ, TR-34722 Istanbul, Turkey -- [Tapan, I.] Uludag Univ, TR-16059 Bursa, Turkey -- [Li, P. R. -- Liu, Q. -- Liu, X. X. -- Lyu, X. R. -- Qiao, C. F. -- Wang, B. L. -- Xu, Q. N. -- Zheng, Y. H.] Univ Chinese Acad Sci, Beijing 100049, Peoples R China -- [Harris, F. A. -- Kornicer, M. -- Luo, T. -- Varner, G. S.] Univ Hawaii, Honolulu, HI 96822 USA -- [Bian, J. M. -- Cronin-Hennessy, D. -- Julin, A. -- Muramatsu, H. -- Poling, R. -- Toth, D.] Univ Minnesota, Minneapolis, MN 55455 USA -- [Ambrose, D. J. -- Thorndike, E. H.] Univ Rochester, Rochester, NY 14627 USA -- [An, Q. -- Fang, X. -- Feng, C. Q. -- Huang, G. S. -- Li, Cheng -- Liang, H. -- Liu, S. B. -- Peng, H. P. -- Shao, M. -- Sun, Y. J. -- Wang, Z. H. -- Yan, L. -- Yan, W. B. -- Yan, W. C. -- Zhang, Z. P. -- Zhao, Lei -- Zhao, Z. G. -- Zhou, X. K. -- Zhou, X. R. -- Zhu, Y. C.] Univ Sci & Technol China, Hefei 230026, Peoples R China -- [Zheng, B.] Univ South China, Hengyan 421001, Peoples R China -- [Hussain, T. -- Malik, Q. A. -- Rashid, K. H. -- Zafar, A. A.] Univ Punjab, Lahore 54590, Pakistan -- [Amoroso, A. -- Bianchi, F. -- Destefanis, M. -- De Mori, F. -- Greco, M. -- Hu, J. F. -- Maggiora, M. -- Marcello, S. -- Sosio, S. -- Spataro, S.] Univ Turin, I-10125 Turin, Italy -- [Fava, L.] Univ Piemonte Orientale, I-15121 Alessandria, Italy -- [Amoroso, A. -- Bianchi, F. -- Destefanis, M. -- De Mori, F. -- Fava, L. -- Greco, M. -- Maggiora, M. -- Marcello, S. -- Sosio, S. -- Spataro, S.] Ist Nazl Fis Nucl, I-10125 Turin, Italy -- [Johansson, T. -- Kupsc, A. -- Schoenning, K. -- Wolke, M.] Uppsala Univ, SE-75120 Uppsala, Sweden -- [Cai, H. -- Han, S. -- Huang, H. P. -- Jiang, L. W. -- Liu, J. P. -- Qin, N. -- Zhang, Z. Y. -- Zhou, X.] Wuhan Univ, Wuhan 430072, Peoples R China -- [Luo, M. X.] Zhejiang Univ, Hangzhou 310027, Peoples R China -- [Du, S. X. -- Li, D. M. -- Zhao, S. J.] Zhengzhou Univ, Zhengzhou 450001, Peoples R China -- [Achasov, M. N. -- Cakir, O. -- Muchnoi, N. Yu. -- Nikolaev, I. B.] Novosibirsk State Univ, Novosibirsk 630090, Russia -- [Achasov, M. N. -- Cakir, O. -- Muchnoi, N. Yu. -- Nikolaev, I. B.] Ankara Univ, TR-06100 Ankara, Turkey -- [Chelkov, G.] Moscow Phys Tech Inst, Dolgoprudnyi 141700, Russia -- [Chelkov, G.] Tomsk State Univ, Functional Elect Lab, Tomsk 634050, Russia -- [Kolcu, O. B.] Istanbul Arel Univ, Istanbul, Turkey -- [Lou, X. C.] Univ Texas Dallas, Richardson, TX 75083 USA -- [Sarantsev, A.] PNPI, Gatchina 188300, Russia -- [Yuncu, A.] Bogazici Univ, TR-34342 Istanbul, Turkey -- [Boger, E. -- Zhemchugov, A.] Moscow Inst Phys & Technol, Moscow 141700, Russia

Subjects
Physics, Nuclear and High Energy Physics, BESIII, детектор, Physics and Astronomy (miscellaneous), Meson, квантовая хромодинамика, Analytical chemistry, FOS: Physical sciences, Branching (polymer chemistry), QCD, 7. Clean energy, MESONS, High Energy Physics - Experiment, NO, Nuclear physics, High Energy Physics - Experiment (hep-ex), бозоны, Pi
Abstract

WOS: 000349437800001, Using 482 pb(-1) of data taken at root s = 4.009 GeV, we measure the branching fractions of the decays of D*(0) into D-0 pi(0) and D-0 gamma to be B(D*(0) -> D-0 pi(0)) = (65.5 +/- 0.8 +/- 0.5)% and B(D*(0) -> D0 gamma) = (34.5 +/- 0.8 +/- 0.5)%, respectively, by assuming that the D*(0) decays only into these two modes. The ratio of the two branching fractions is B(D*(0) -> D-0 pi(0))/B(D*(0) -> D-0 gamma) = 1.90 +/- 0.07 +/- 0.05, which is independent of the assumption made above. The first uncertainties are statistical and the second ones systematic. The precision is improved by a factor of 3 compared to the present world average values., National Key Basic Research Program of China [2015CB856700]; Joint Funds of the National Natural Science Foundation of China [11079008, 11179007, U1232201, U1332201]; National Natural Science Foundation of China (NSFC) [10935007, 11121092, 11125525, 11235011, 11322544, 11335008]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS [KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG [Collaborative Research Center CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [DPT2006 K-120470]; Russian Foundation for Basic Research [14-07-91152]; U.S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea [R32-2008-000-10155-0], The BESIII Collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. This work is supported in part by the National Key Basic Research Program of China under Contract No. 2015CB856700; Joint Funds of the National Natural Science Foundation of China under Contracts No. 11079008, No. 11179007, No. U1232201, and No. U1332201; National Natural Science Foundation of China (NSFC) under Contracts No. 10935007, No. 11121092, No. 11125525, No. 11235011, No. 11322544, and No. 11335008; the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS under Contracts No. KJCX2-YW-N29 and No. KJCX2-YW-N45; 100 Talents Program of CAS; INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Contract No. Collaborative Research Center CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006 K-120470; Russian Foundation for Basic Research under Contract No. 14-07-91152; U.S. Department of Energy under Contracts No. DE-FG02-04ER41291, No. DE-FG02-05ER41374, No. DE-FG02-94ER40823, and No. DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea under Contract No. R32-2008-000-10155-0.

Published
2015

108. Study of dynamics of D0 --> K-e+nu_e and D0 --> pi-e+nu_e decays

Author

Ablikim, M., Achasov, M. N., Ai, X. C., Albayrak, O., Albrecht, M., Ambrose, D. J., Amoroso, A., An, F. F., An, Q., Bai, J. Z., Ferroli, R. Baldini, Ban, Y., Bennett, D. W., Bennett, J. V., Bertani, M., Bettoni, D., Bian, J. M., Bianchi, F., Boger, E., Boyko, I., Briere, R. A., Cai, H., Cai, X., Cakir, O., Calcaterra, A., Cao, G. F., Cetin, S. A., Chang, J. F., Chelkov, G., Chen, G., Chen, H. S., Chen, H. Y., Chen, J. C., Chen, M. L., Chen, S. J., Chen, X., Chen, X. R., Chen, Y. B., Cheng, H. P., Chu, X. K., Cibinetto, G., Dai, H. L., Dai, J. P., Dbeyssi, A., Dedovich, D., Deng, Z. Y., Denig, A., Denysenko, I., Destefanis, M., De Mori, F., Ding, Y., Dong, C., Dong, J., Dong, L. Y., Dong, M. Y., Du, S. X., Duan, P. F., Eren, E. E., Fan, J. Z., Fang, J., Fang, S. S., Fang, X., Fang, Y., Fava, L., Feldbauer, F., Felici, G., Feng, C. Q., Fioravanti, E., Fritsch, M., Fu, C. D., Gao, Q., Gao, X. Y., Gao, Y., Gao, Z., Garzia, I., Goetzen, K., Gong, W. X., Gradl, W., Greco, M., Gu, M. 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Subjects
ratio, effective field theory, branching fractions, exclusive semileptonic decays, heavy, transition form factors, exclusive semileptonic decays, transition form factors, effective field theory, branching fractions, heavy, mesons, ratio, mesons, NO
Abstract

WOS: 000363237600002, In an analysis of a 2.92 fb(-1) data sample taken at 3.773 GeV with the BESIII detector operated at the BEPCII collider, we measure the absolute decay branching fractions B(D-0 -> K(-)e(+)nu(e)) = (3.505 +/- 0.014 +/- 0.033)% and B(D-0 -> pi(-)e(+)nu(e)) = (0.295 +/- 0.004 +/- 0.003)%. From a study of the differential decay rates we obtain the products of hadronic form factor and the magnitude of the Cabibbo-Kobayashi-Maskawa (CKM) matrix element f(+)(K)(0)vertical bar V-cs vertical bar = 0.7172 +/- 0.0025 +/- 0.0035 and f(+)(pi)(0)vertical bar V-cd vertical bar = 0.1435 +/- 0.0018 +/- 0.0009. Combining these products with the values of vertical bar V-cs(d)vertical bar from the SM constraint fit, we extract the hadronic form factors f(+)(K)(0) = 0.7368 +/- 0.0026 +/- 0.0036 and f(+)(pi)(0) = 0.6372 +/- 0.0080 +/- 0.0044, and their ratio f(+)(pi)(0)/f(+)(K)(0) = 0.8649 +/- 0.0112 +/- 0.0073. These form factors and their ratio are used to test unquenched lattice QCD calculations of the form factors and a light cone sum rule (LCSR) calculation of their ratio. The measured value of f(+)(K(pi))(0)vertical bar V-cs(d)vertical bar and the lattice QCD value for f(+)(K(pi))(0) are used to extract values of the CKM matrix elements of vertical bar V-cs vertical bar = 0.9601 +/- 0.0033 +/- 0.0047 +/- 0.0239 and vertical bar V-cd vertical bar = 0.2155 +/- 0.0027 +/- 0.0014 +/- 0.0094, where the third errors are due to the uncertainties in lattice QCD calculations of the form factors. Using the LCSR value for f(+)(pi)(0)/f(+)(K)(0), we determine the ratio vertical bar V-cd vertical bar/vertical bar V-cs vertical bar = 0.238 +/- 0.004 +/- 0.002 +/- 0.011, where the third error is from the uncertainty in the LCSR normalization. In addition, we measure form factor parameters for three different theoretical models that describe the weak hadronic charged currents for these two semileptonic decays. All of these measurements are the most precise to date., National Key Basic Research Program of China [2009CB825204, 2015CB856700]; National Natural Science Foundation of China (NSFC) [10935007, 11125525, 11235011, 11322544, 11335008, 11425524]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; NSFC [11179007, U1232201, U1332201]; CAS [11179007, U1232201, U1332201, KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; INPAC; Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Collaborative Research Center [CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [DPT2006K-120470]; Russian Foundation for Basic Research [14-07-91152]; U.S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; Institute for Basic Science, Korea [IBS-R016-D1]; Swedish Research Council, The BESIII collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. This work is supported in part by National Key Basic Research Program of China under Contracts No. 2009CB825204, No. 2015CB856700; National Natural Science Foundation of China (NSFC) under Contracts No. 10935007, No. 11125525, No. 11235011, No. 11322544, No. 11335008, No. 11425524; the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; Joint Large-Scale Scientific Facility Funds of the NSFC and CAS under Contracts No. 11179007, No. U1232201, No. U1332201; CAS under Contracts No. KJCX2-YW-N29, No. KJCX2-YW-N45; 100 Talents Program of CAS; INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Collaborative Research Center Contract No. CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006K-120470; Russian Foundation for Basic Research under Contract No. 14-07-91152; U.S. Department of Energy under Contracts No. DE-FG02-04ER41291, No. DE-FG02-05ER41374, No. DE-FG02-94ER40823, No. DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; Institute for Basic Science, Korea, Project Code IBS-R016-D1; the Swedish Research Council.

Published
2015

109. Search for C-parity violation in J/psi -> gamma gamma and gamma phi

Author

Ablikim, M., Achasov, M. . N., X. . C., Ai, Albayrak, O., Albrecht, M., Ambrose, D. . J., Amoroso, Antonio, F. . F., An, An, Q., Bai, J. . Z., Baldini Ferroli, R., Ban, Y., Bennett, D. . W., Bennett, J. . V., Bertani, M., Bettoni, D., Bian, J. . M., Bianchi, Fabrizio, Boger, E., Bondarenko, O., Boyko, I., Braun, S., Briere, R. . A., Cai, H., Cai, X., Cakir, O., Calcaterra, A., Cao, G. . F., Cetin, S. . A., Chang, J. . F., Chelkov, G., Chen, G., Chen, H. . S., Chen, J. . C., Chen, M. . L., Chen, S. . J., Chen, X., Chen, X. . R., Chen, Y. . B., Cheng, H. . P., Chu, X. . K., Chu, Y. . P., Cibinetto, G., Cronin Hennessy, D., Dai, H. . L., Dai, J. . P., Dedovich, D., Deng, Z. . Y., Denig, A., Denysenko, I., Destefanis, MARCO GIOVANNI, DE MORI, Francesca, Ding, Y., Dong, C., Dong, J., Dong, L. . Y., Dong, M. . Y., S. . X., Du, Fan, J. . Z., Fang, J., Fang, S. . S., Fang, Y., Fava, L., Feldbauer, F., Felici, G., Feng, C. . Q., Fioravanti, E., C. . D., Fu, Gao, Q., Gao, Y., Garzia, I., Geng, C., Goetzen, K., Gong, W. . X., Gradl, W., Greco, Michela, M. . H., Gu, Y. . T., Gu, Guan, Y. . H., Guo, A. . Q., Guo, L. . B., Guo, T., Guo, Y. . P., Haddadi, Z., Han, S., Han, Y. . L., Harris, F. . A., K. . L., He, Z. . Y., He, Held, T., Heng, Y. . K., Hou, Z. . L., Hu, C., H. . M., Hu, Hu, Jifeng, Hu, T., Huang, G. . M., Huang, G. . S., Huang, H. . P., Huang, J. . S., Huang, X. . T., Huang, Y., Hussain, T., Ji, Q., Q. . P., Ji, X. . B., Ji, X. . L., Ji, Jiang, L. . L., Jiang, L. . W., Jiang, X. . S., Jiao, J. . B., Jiao, Z., Jin, D. . P., Jin, S., Johansson, T., Julin, A., Kalantar Nayestanaki, N., Kang, X. . L., Kang, X. . S., Kavatsyuk, M., B. . C., Ke, Kloss, B., Kolcu, O. . B., Kopf, B., Kornicer, M., Kuehn, W., Kupsc, A., Lai, W., Lange, J. . S., Lara, M., Larin, P., Leyhe, M., Cheng, Li, Cui, Li, D. . M., Li, Li, F., Li, G., H. . B., Li, J. . C., Li, Jin, Li, Li, K., Q. . J., Li, Li, T., W. . D., Li, W. . G., Li, X. . H., Li, X. . 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Abstract

WOS: 000345591500001, Using 1.06 x 10(8) psi(3686) events recorded in e(+)e(-) collisions at root s = 3.686 GeV with the BESIII at the BEPCII collider, we present searches for C-parity violation in J/psi -> gamma gamma and gamma phi decays via psi(3686) -> J/psi pi(+)pi(-). No significant signals are observed in either channel. Upper limits on the branching fractions are set to be B(J/psi -> gamma gamma) < 2.7 x 10(-7) and B(J/psi -> gamma phi) < 1.4 x 10(-6) at the 90% confidence level. The former is one order of magnitude more stringent than the previous upper limit, and the latter represents the first limit on this decay channel., National Key Basic Research Program of China [2015CB856700]; Joint Funds of the National Natural Science Foundation of China [11079008, 11179007, U1232201, U1332201]; National Natural Science Foundation of China (NSFC) [11205082, 11475090, 10935007, 11121092, 11125525, 11235011, 11322544, 11335008]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS [KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; German Research Foundation DFG [Collaborative Research Center CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [14-07-91152]; U.S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of the National Research Foundation of Korea [R32-2008-000-10155-0], The BESIII collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. This work is supported in part by the National Key Basic Research Program of China under Contract No. 2015CB856700; Joint Funds of the National Natural Science Foundation of China under Contracts No. 11079008, No. 11179007, No. U1232201, and No. U1332201; National Natural Science Foundation of China (NSFC) under Contracts No. 11205082, No. 11475090, No. 10935007, No. 11121092, No. 11125525, No. 11235011, No. 11322544, No. 11335008; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS under Contracts No. KJCX2-YW-N29, No. KJCX2-YW-N45; the 100 Talents Program of CAS; German Research Foundation DFG under Contract No. Collaborative Research Center CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006K-120470; Russian Foundation for Basic Research under Contract No. 14-07-91152; U.S. Department of Energy under Contracts No. DE-FG02-04ER41291, No. DE-FG02-05ER41374, No. DE-FG02-94ER40823, No. DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of the National Research Foundation of Korea under Contract No. R32-2008-000-10155-0.

Published
2014

110. Search for the weak decays J/psi -> D-s(()*()-) e(+)nu(e) + c.c

Author

Ablikim, M., Achasov, M. . N., X. . C., Ai, Albayrak, O., Albrecht, M., Ambrose, D. . J., Amoroso, Antonio, F. . F., An, An, Q., Bai, J. . Z., Baldini Ferroli, R., Ban, Y., Bennett, D. . W., Bennett, J. . V., Bertani, M., Bettoni, D., Bian, J. . M., Bianchi, Fabrizio, Boger, E., Bondarenko, O., Boyko, I., Briere, R. . A., Cai, H., Cai, X., Cakir, O., Calcaterra, A., Cao, G. . F., Cetin, S. . A., Chang, J. . F., Chelkov, G., Chen, G., Chen, H. . S., Chen, H. . Y., Chen, J. . C., Chen, M. . L., Chen, S. . J., Chen, X., Chen, X. . R., Chen, Y. . B., Cheng, H. . P., Chu, X. . K., Chu, Y. . P., Cibinetto, G., Cronin Hennessy, D., Dai, H. . L., Dai, J. . P., Dedovich, D., Deng, Z. . Y., Denig, A., Denysenko, I., Destefanis, MARCO GIOVANNI, DE MORI, Francesca, Ding, Y., Dong, C., Dong, J., Dong, L. . Y., Dong, M. . Y., S. . X., Du, Duan, P. . F., Fan, J. . Z., Fang, J., Fang, S. . S., Fang, X., Fang, Y., Fava, L., Feldbauer, F., Felici, G., Feng, C. . Q., Fioravanti, E., C. . D., Fu, Gao, Q., Gao, Y., Garzia, I., Goetzen, K., Gong, W. . X., Gradl, W., Greco, Michela, M. . H., Gu, Y. . T., Gu, Guan, Y. . H., Guo, A. . Q., Guo, L. . B., Guo, T., Guo, Y., Guo, Y. . P., Haddadi, Z., Hafner, A., Han, S., Han, Y. . L., Harris, F. . A., K. . L., He, Z. . Y., He, Held, T., Heng, Y. . K., Hou, Z. . L., Hu, C., H. . M., Hu, Hu, Jifeng, Hu, T., Hu, Y., Huang, G. . M., Huang, G. . S., Huang, H. . P., Huang, J. . S., Huang, X. . T., Huang, Y., Hussain, T., Ji, Q., Q. . P., Ji, X. . B., Ji, X. . L., Ji, Jiang, L. . L., Jiang, L. . W., Jiang, X. . S., Jiao, J. . B., Jiao, Z., Jin, D. . P., Jin, S., Johansson, T., Julin, A., Kalantar Nayestanaki, N., Kang, X. . L., Kang, X. . S., Kavatsyuk, M., B. . C., Ke, Kliemt, R., Kloss, B., Kolcu, O. . B., Kopf, B., Kornicer, M., Kuehn, W., Kupsc, A., Lai, W., Lange, J. . S., Lara, M., Larin, P., C. . H., Li, Cheng, Li, D. . M., Li, Li, F., Li, G., H. . B., Li, J. . C., Li, Jin, Li, Li, K., P. . R., Li, Li, T., W. . D., Li, W. . 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X. -- Li, D. M. -- Zhao, Q. W.] Zhengzhou Univ, Zhengzhou 450001, Peoples R China -- [Achasov, M. N. -- Muchnoi, N. Yu. -- Nikolaev, I. B.] Novosibirsk State Univ, Novosibirsk 630090, Russia -- [Boger, E. -- Chelkov, G. -- Zhao, Z. G.] Moscow Inst Phys & Technol, Moscow 141700, Russia -- [Chelkov, G.] Tomsk State Univ, Funct Elect Lab, Tomsk 634050, Russia -- [Lou, X. C.] Univ Texas Dallas, Richardson, TX 75083 USA -- [Sarantsev, A.] PNPI, Gatchina 188300, Russia -- [Yuncu, A.] Bogazici Univ, TR-34342 Istanbul, Turkey -- [Kolcu, O. B.] Istanbul Arel Univ, Istanbul, Turkey

Abstract

WOS: 000348360900003, Using a sample of 2.25 x 10(8) J/psi events collected with the BESIII detector at the BEPCII collider, we search for the J/psi semileptonic weak decay J/psi -> D-s(-) e(+)nu(e) +c.c. with a much higher sensitivity than previous searches. We also perform the first search for J/psi -> D-s(*-) e(+) nu(e) + c.c. No significant excess of a signal above background is observed in either channel. At the 90% confidence level, the upper limits are determined to be B(J/psi -> D-s(-) e(+) nu(e) + c.c.) < 1.3 x 10(-6) and B(J/psi -> D-s*(-) e(+) nu(e) + c.c.) < 1.8 x 10(-6), respectively. Both are consistent with Standard Model predictions., National Key Basic Research Program of China [2015CB856700]; Joint Funds of the National Natural Science Foundation of China [11079008, 11179007, 11179014, U1332201]; National Natural Science Foundation of China (NSFC) [10625524, 10821063, 10835001, 11125525, 11235011, 11335008, 11275189]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS [KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; German Research Foundation DFG [CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [DPT2006K-120470]; Russian Foundation for Basic Research [14-07-91152]; U.S. Department of Energy, The BESIII collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. This work is supported in part by National Key Basic Research Program of China under Contract No. 2015CB856700; Joint Funds of the National Natural Science Foundation of China under Contracts No. 11079008, No. 11179007, No. 11179014 and No. U1332201; National Natural Science Foundation of China (NSFC) under Contracts No. 10625524, No. 10821063, No. 10835001, No. 11125525, No. 11235011, and No. 11335008; the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS under Contracts No. KJCX2-YW-N29 and No. KJCX2-YW-N45; 100 Talents Program of CAS; German Research Foundation DFG under Contract No. Collaborative Research Center CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006K-120470; National Natural Science Foundation of China (NSFC) under Contract No. 11275189; Russian Foundation for Basic Research under Contract No. 14-07-91152; U.S. Department of Energy under Contracts No. DE-FG02-04ER41291, No. DE-FG02-05ER41374, No. DE-FG02-94ER40823, and No. DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea under Contract No. R32-2008-000-10155-0.

Published
2014

111. Ling-Gui-Zhu-Gan decoction ameliorates nonalcoholic fatty liver disease via modulating the gut microbiota.

Author

Chen L-p, Zhang L-f, Liu S, Hua H, Zhang L, Liu B-c, and Wang R-r

Subjects
Animals, Mice, Male, Dysbiosis drug therapy, Dysbiosis microbiology, Liver drug effects, Liver metabolism, Mice, Inbred C57BL, Bile Acids and Salts metabolism, Fatty Acids, Volatile metabolism, Lipid Metabolism drug effects, Signal Transduction drug effects, Plant Extracts, Non-alcoholic Fatty Liver Disease drug therapy, Non-alcoholic Fatty Liver Disease metabolism, Gastrointestinal Microbiome drug effects, Drugs, Chinese Herbal pharmacology, Drugs, Chinese Herbal therapeutic use, Disease Models, Animal, Diet, High-Fat adverse effects
Abstract

Numerous studies have supported that nonalcoholic fatty liver disease (NAFLD) is highly associated with gut microbiota dysbiosis. Ling-Gui-Zhu-Gan decoction (LG) has been clinically used to treat NAFLD, but the underlying mechanism remains unknown. This study investigated the therapeutic effect and mechanisms of LG in mice with NAFLD induced by a high-fat diet (HD). An HD-induced NAFLD mice model was established to evaluate the efficacy of LG followed by biochemical and histopathological analysis. Metagenomics, metabolomics, and transcriptomics were used to explore the structure and metabolism of the gut microbiota. LG significantly improved hepatic function and decreased lipid droplet accumulation in HD-induced NAFLD mice. LG reversed the structure of the gut microbiota that is damaged by HD and improved intestinal barrier function. Meanwhile, the LG group showed a lower total blood bile acids (BAs) concentration, a shifted BAs composition, and a higher fecal short-chain fatty acids (SCFAs) concentration. Furthermore, LG could regulate the hepatic expression of genes associated with the primary BAs biosynthesis pathway and peroxisome proliferator-activated receptor (PPAR) signaling pathway. Our study suggested that LG could ameliorate NAFLD by altering the structure and metabolism of gut microbiota, while BAs and SCFAs are considered possible mediating substances., Importance: Until now, there has still been no study on the gut microbiota and metabolomics of Ling-Gui-Zhu-Gan decoction (LG) in nonalcoholic fatty liver disease (NAFLD) mouse models. Our study is the first to report on the reshaping of the structure and metabolism of the gut microbiota by LG, as well as explore the potential mechanism underlying the improvement of NAFLD. Specifically, our study demonstrates the potential of gut microbial-derived short-chain fatty acids (SCFAs) and blood bile acids (BAs) as mediators of LG therapy for NAFLD in animal models. Based on the results of transcriptomics, we further verified that LG attenuates NAFLD by restoring the metabolic disorder of BAs via the up-regulation of Fgf15/FXR in the ileum and down-regulation of CYP7A1/FXR in the liver. LG also reduces lipogenesis in NAFLD mice by mediating the peroxisome proliferator-activated receptor (PPAR) signaling pathway, which then contributes to reducing hepatic inflammation and improving intestinal barrier function to treat NAFLD., Competing Interests: The authors declare no conflict of interest.

Published
2024
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