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3,456 results on '"Arnold, Matthew"'

101. Thrombosis with thrombocytopenia after AZD1222 (ChAdOx1 nCov-19) vaccination: Case characteristics and associations

Author

Laffan, Michael A, primary, Rees, Sue, additional, Yadavalli, Madhavi, additional, Ferstenberg, Lisa Beth, additional, Kumar Shankar, Nirmal, additional, Medin, Jennie, additional, Foskett, Nadia, additional, Arnold, Matthew, additional, Gomes da Silva, Hugo, additional, Bhuyan, Prakash, additional, and Nord, Magnus, additional

Published
2022
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102. Healthcare resource utilisation and related costs of patients with CKD from the UK: a report from the DISCOVER CKD retrospective cohort

Author

Pollock, Carol, primary, James, Glen, additional, Garcia Sanchez, Juan Jose, additional, Carrero, Juan Jesus, additional, Arnold, Matthew, additional, Lam, Carolyn S P, additional, Chen, Hungta (Tony), additional, Nolan, Stephen, additional, Pecoits-Filho, Roberto, additional, and Wheeler, David C, additional

Published
2022
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103. Incremental value of risk factor variability for cardiovascular risk prediction in individuals with type 2 diabetes: results from UK primary care electronic health records

Author

Xu, Zhe, primary, Arnold, Matthew, additional, Sun, Luanluan, additional, Stevens, David, additional, Chung, Ryan, additional, Ip, Samantha, additional, Barrett, Jessica, additional, Kaptoge, Stephen, additional, Pennells, Lisa, additional, Di Angelantonio, Emanuele, additional, and Wood, Angela M, additional

Published
2022
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112. An Empirical Study of Selective Optimization

Author

Arnold, Matthew, Hind, Michael, Ryder, Barbara G., Goos, G., editor, Hartmanis, J., editor, van Leeuwen, J., editor, Midkiff, Samuel P., editor, Moreira, José E., editor, Gupta, Manish, editor, Chatterjee, Siddhartha, editor, Ferrante, Jeanne, editor, Prins, Jan, editor, Pugh, William, editor, and Tseng, Chau-Wen, editor

Published
2001
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114. Spontaneous Emergence of Optically Polarizing Nanoscale Structures by Co-Deposition of Aluminum with Refractory Metals: Implications for High-Temperature Polarizers

Author

Tai, Matthew C., primary, Arnold, Matthew D., additional, Estherby, Caleb, additional, de Silva, Kaludewa S. B., additional, Gentle, Angus R., additional, Cortie, David L., additional, Mitchell, David R. G., additional, Westerhausen, Mika T., additional, and Cortie, Michael B., additional

Published
2022
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115. Coexistence between similar invaders: The case of two cosmopolitan exotic insects

Author

Arnold, Matthew B., primary, Back, Michael, additional, Crowell, Michael Daniel, additional, Farooq, Nageen, additional, Ghimire, Prashant, additional, Obarein, Omon A., additional, Smart, Kyle E., additional, Taucher, Trixie, additional, VanderJeugdt, Erin, additional, Perry, Kayla I., additional, Landis, Douglas A., additional, and Bahlai, Christie A., additional

Published
2022
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116. Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs

Author

Gestuveo, Rommel J., primary, Parry, Rhys, additional, Dickson, Laura B., additional, Lequime, Sebastian, additional, Sreenu, Vattipally B., additional, Arnold, Matthew J., additional, Khromykh, Alexander A., additional, Schnettler, Esther, additional, Lambrechts, Louis, additional, Varjak, Margus, additional, and Kohl, Alain, additional

Published
2022
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117. RETRACTED: Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses

Author

Sofianopoulou, Eleni, Kaptoge, Stephen K, Afzal, Shoaib, Jiang, Tao, Gill, Dipender, Gundersen, Thomas E, Bolton, Thomas R, Allara, Elias, Arnold, Matthew G, Mason, Amy M, Chung, Ryan, Pennells, Lisa A M, Shi, Fanchao, Sun, Luanluan, Willeit, Peter, Forouhi, Nita G, Langenberg, Claudia, Sharp, Stephen J, Panico, Salvatore, Engström, Gunnar, Melander, Olle, Tong, Tammy Y N, Perez-Cornago, Aurora, Norberg, Margareta, Johansson, Ingegerd, Katzke, Verena, Srour, Bernard, José Sánchez, María, Redondo-Sánchez, Daniel, Olsen, Anja, Dahm, Christina C, Overvad, Kim, Brustad, Magritt, Skeie, Guri, Moreno-Iribas, Conchi, Onland-Moret, N Charlotte, van der Schouw, Yvonne T, Tsilidis, Konstantinos K, Heath, Alicia K, Agnoli, Claudia, Krogh, Vittorio, de Boer, Ian H, Kobylecki, Camilla Jannie, Çolak, Yunus, Zittermann, Armin, Sundström, Johan, Welsh, Paul, Weiderpass, Elisabete, Aglago, Elom K, Ferrari, Pietro, Clarke, Robert, Boutron, Marie-Christine, Severi, Gianluca, MacDonald, Conor, Providencia, Rui, Masala, Giovanna, Zamora Ros, Raul, Boer, Jolanda, Verschuren, WM Monique, Cawthon, Peggy, Schierbeck, Louise L, Cooper, Cyrus, Schulze, Matthias B, Bergmann, Manuela M, Hannemann, Anke, Kiechl, Stefan, Brenner, Hermann, van Schoor, Natasja M, Albertorio, Juan R, Sacerdote, Carlotta, Linneberg, Allan, Kårhus, Line L, Huerta, José María, Imaz, Liher, Joergensen, Christel, Ben-Shlomo, Yoav, Lundqvist, Annamari, Gallacher, John, Sattar, Naveed, Wood, Angela M, Wareham, Nicholas J, Nordestgaard, Børge G, Di Angelantonio, Emanuele, Danesh, John, Butterworth, Adam S, and Burgess, Stephen

Published
2021
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119. Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses

Author

Sofianopoulou, Eleni, primary, Kaptoge, Stephen K, additional, Afzal, Shoaib, additional, Jiang, Tao, additional, Gill, Dipender, additional, Gundersen, Thomas E, additional, Bolton, Thomas R, additional, Allara, Elias, additional, Arnold, Matthew G, additional, Mason, Amy M, additional, Chung, Ryan, additional, Pennells, Lisa A M, additional, Shi, Fanchao, additional, Sun, Luanluan, additional, Willeit, Peter, additional, Forouhi, Nita G, additional, Langenberg, Claudia, additional, Sharp, Stephen J, additional, Panico, Salvatore, additional, Engström, Gunnar, additional, Melander, Olle, additional, Tong, Tammy Y N, additional, Perez-Cornago, Aurora, additional, Norberg, Margareta, additional, Johansson, Ingegerd, additional, Katzke, Verena, additional, Srour, Bernard, additional, José Sánchez, María, additional, Redondo-Sánchez, Daniel, additional, Olsen, Anja, additional, Dahm, Christina C, additional, Overvad, Kim, additional, Brustad, Magritt, additional, Skeie, Guri, additional, Moreno-Iribas, Conchi, additional, Onland-Moret, N Charlotte, additional, van der Schouw, Yvonne T, additional, Tsilidis, Konstantinos K, additional, Heath, Alicia K, additional, Agnoli, Claudia, additional, Krogh, Vittorio, additional, de Boer, Ian H, additional, Kobylecki, Camilla Jannie, additional, Çolak, Yunus, additional, Zittermann, Armin, additional, Sundström, Johan, additional, Welsh, Paul, additional, Weiderpass, Elisabete, additional, Aglago, Elom K, additional, Ferrari, Pietro, additional, Clarke, Robert, additional, Boutron, Marie-Christine, additional, Severi, Gianluca, additional, MacDonald, Conor, additional, Providencia, Rui, additional, Masala, Giovanna, additional, Zamora Ros, Raul, additional, Boer, Jolanda, additional, Verschuren, WM Monique, additional, Cawthon, Peggy, additional, Schierbeck, Louise L, additional, Cooper, Cyrus, additional, Schulze, Matthias B, additional, Bergmann, Manuela M, additional, Hannemann, Anke, additional, Kiechl, Stefan, additional, Brenner, Hermann, additional, van Schoor, Natasja M, additional, Albertorio, Juan R, additional, Sacerdote, Carlotta, additional, Linneberg, Allan, additional, Kårhus, Line L, additional, Huerta, José María, additional, Imaz, Liher, additional, Joergensen, Christel, additional, Ben-Shlomo, Yoav, additional, Lundqvist, Annamari, additional, Gallacher, John, additional, Sattar, Naveed, additional, Wood, Angela M, additional, Wareham, Nicholas J, additional, Nordestgaard, Børge G, additional, Di Angelantonio, Emanuele, additional, Danesh, John, additional, Butterworth, Adam S, additional, and Burgess, Stephen, additional

Published
2021
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123. TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions

Author

Griffin, Patrick T, primary, Kane, Alice E, additional, Trapp, Alexandre, additional, Li, Jien, additional, Arnold, Matthew, additional, Poganik, Jesse R, additional, McNamara, Maeve S, additional, Meer, Margarita V, additional, Hoffman, Noah, additional, Amorim, João, additional, Tian, Xiao, additional, MacArthur, Michael R, additional, Mitchell, Sarah J, additional, Mueller, Amber L, additional, Carmody, Colleen, additional, Vera, Daniel L, additional, Kerepesi, Csaba, additional, Hooten, Nicole Noren, additional, Mitchell, James R, additional, Evans, Michele K, additional, Gladyshev, Vadim N, additional, and Sinclair, David A, additional

Published
2021
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125. Boston Cognitive Assessment (BOCA) — a comprehensive self-administered smartphone- and computer-based at-home test for longitudinal tracking of cognitive performance

Author

Vyshedskiy, Andrey, primary, Netson, Rebecca, additional, Fridberg, Elisabeth, additional, Jagadeesan, Priyanka, additional, Arnold, Matthew, additional, Barnett, Sophie, additional, Gondalia, Anjali, additional, Maslova, Victoria, additional, deTorres, Lauren, additional, Ostrovsky, Simone, additional, Durakovic, Danijel, additional, Savchenko, Andrei, additional, McNett, Sienna, additional, Kogan, Mikhail, additional, Piryatinsky, Irene, additional, and Gold, Dov, additional

Published
2021
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129. Assessment of Vascular Event Prevention and Cognitive Function Among Older Adults With Preexisting Vascular Disease or Diabetes: A Secondary Analysis of 3 Randomized Clinical Trials

Author

Offer, Alison, Arnold, Matthew, Clarke, Robert, Bennett, Derrick, Bowman, Louise, Bulbulia, Richard, Haynes, Richard, Li, Jing, Hopewell, Jemma C, Landray, Martin, Armitage, Jane, Collins, Rory, Parish, Sarah, Heart Protection Study (HPS), Study Of The Effectiveness Of Additional Reductions In Cholesterol And Homocysteine (SEARCH), And Treatment Of HDL (High-Density Lipoprotein) To Reduce The Incidence Of Vascular Events (HPS2-THRIVE) Collaborative Grou, Arnold, Matthew [0000-0001-6339-1115], and Apollo - University of Cambridge Repository

Subjects
Intelligence Tests, Male, Incidence, Myocardial Infarction, Middle Aged, Stroke, Cognition, Cognitive Aging, Outcome Assessment, Health Care, Diabetes Mellitus, Humans, Female, Vascular Diseases, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Geriatric Assessment, Aged
Abstract

IMPORTANCE: Acquisition of reliable randomized clinical trial evidence of the effects of cardiovascular interventions on cognitive decline is a priority. OBJECTIVES: To estimate the association of cognitive aging with the avoidance of vascular events in cardiovascular intervention trials and understand whether reports of nonsignificant results exclude worthwhile benefit. DESIGN, SETTING, AND PARTICIPANTS: This secondary analysis of 3 randomized clinical trials in participants with preexisting occlusive vascular disease or diabetes included survivors to final in-trial follow-up in the Heart Protection Study (HPS), Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH), and Treatment of HDL (High-Density Lipoprotein) to Reduce the Incidence of Vascular Events (HPS2-THRIVE) trials of lipid modification for prevention of cardiovascular events. Data were collected from February 1994 through January 2013 and analyzed from January 2015 through December 2018. EXPOSURES: Incident vascular events and diabetes and statin therapy. MAIN OUTCOMES AND MEASURES: Cognitive function was assessed at the end of a mean (SD) of 4.9 (1.5) years of follow-up using a 14-item verbal test. Associations of the incidence of vascular events and new-onset diabetes during the trials, with cognitive function at final in-trial follow-up were estimated and expressed as years of cognitive aging (using the association of the score with age >60 years). The benefit on cognitive aging mediated through the effects of lowering low-density lipoprotein cholesterol levels on events was estimated by applying these findings to nonfatal event differences observed with statin therapy in the HPS trial. RESULTS: Among 45 029 participants undergoing cognitive assessment, mean (SD) age was 67.9 (8.0) years; 80.7% were men. Incident stroke (n = 1197) was associated with 7.1 (95% CI, 5.7-8.5) years of cognitive aging; incident transient ischemic attack, myocardial infarction, heart failure, and new-onset diabetes were associated with 1 to 2 years of cognitive aging. In HPS, randomization to statin therapy for 5 years resulted in 2.0% of survivors avoiding a nonfatal stroke or transient ischemic attack and 2.4% avoiding a nonfatal cardiac event, which yielded an expected reduction in cognitive aging of 0.15 (95% CI, 0.11-0.19) years. With 15 926 participants undergoing cognitive assessment, HPS had 80% power to detect a 1-year (ie, 20% during the 5 years) difference in cognitive aging. CONCLUSIONS AND RELEVANCE: The expected cognitive benefits of the effects of preventive therapies on cardiovascular events during even the largest randomized clinical trials may have been too small to be detectable. Hence, nonsignificant findings may not provide good evidence of a lack of worthwhile benefit on cognitive function with prolonged use of such therapies. TRIAL REGISTRATION: isrctn.com and ClinicalTrials.gov Identifiers: ISRCTN48489393, ISRCTN74348595, and NCT00461630.

Published
2020
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136. North Carolina's nonconformity to federal bonus depreciation: mechanics and planning opportunities

Author

Price, Violet, Arnold, Matthew, and Sheats, Livingston

Subjects
Transfer taxes -- Laws, regulations and rules, Income tax -- Laws, regulations and rules, Depreciation -- Laws, regulations and rules -- Taxation, Government regulation, Banking, finance and accounting industries, Business, North Carolina. General Statutes N.C. Gen. Stat. 105-153.6(a) N.C. Gen. Stat. 105-130.5B(a)
Abstract

While many states use a fixed-date conformity approach (i.e., a state adopts Internal Revenue Code changes at a certain date) to disallow bonus depreciation, North Carolina's scheme imposes a unique [...]

Published
2017

145. Methods and rationale of the DISCOVER CKD global observational study

Author

Pecoits-Filho, Roberto, primary, James, Glen, additional, Carrero, Juan Jesus, additional, Wittbrodt, Eric, additional, Fishbane, Steven, additional, Sultan, Alyshah Abdul, additional, Heerspink, Hiddo J L, additional, Hedman, Katarina, additional, Kanda, Eiichiro, additional, Chen, Hungta (Tony), additional, Kashihara, Naoki, additional, Sloand, James, additional, Kosiborod, Mikhail, additional, Kumar, Supriya, additional, Lainscak, Mitja, additional, Arnold, Matthew, additional, Lam, Carolyn S P, additional, Holmqvist, Björn, additional, Pollock, Carol, additional, Fenici, Peter, additional, Stenvinkel, Peter, additional, Medin, Jennie, additional, and Wheeler, David C, additional

Published
2021
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146. Militias: a conceptual framework

Author

Alden, Chris, Thakur, Monika, and Arnold, Matthew B.

Subjects
Market trend/market analysis, Military and naval science, Political science
Abstract

ABSTRACT While the presence of militia in conflicts dates back several centuries, their current nature and importance remains unique and in need of further analysis and understanding. This article attempts [...]

Published
2011

148. Assessment of the Role of Carotid Atherosclerosis in the Association Between Major Cardiovascular Risk Factors and Ischemic Stroke Subtypes

Author

Parish, Sarah, Arnold, Matthew, Clarke, Robert, Du, Huaidong, Wan, Eric, Kurmi, Om, Chen, Yiping, Guo, Yu, Bian, Zheng, Collins, Rory, Li, Liming, Chen, Zhengming, China Kadoorie Biobank Collaborative Group, Arnold, Matthew [0000-0001-6339-1115], and Apollo - University of Cambridge Repository

Subjects
Adult, Carotid Artery Diseases, Male, Blood Pressure, Comorbidity, Middle Aged, Stroke, Cross-Sectional Studies, Risk Factors, Case-Control Studies, Humans, Carotid Stenosis, Female, cardiovascular diseases, Prospective Studies, Ultrasonography
Abstract

IMPORTANCE: A better understanding of the role of atherosclerosis in the development of ischemic stroke subtypes could help to improve strategies for prevention of stroke worldwide. OBJECTIVE: To assess the role of carotid atherosclerosis in the association between major cardiovascular risk factors and ischemic stroke subtypes. DESIGN, SETTING, AND PARTICIPANTS: The prospective China Kadoorie Biobank cohort study was conducted in the general population of 5 urban and 5 rural areas in China, with a baseline survey obtained between June 2004 and July 2008. A random sample of 23 973 participants with no history of cardiovascular disease at enrollment who had carotid artery ultrasonographic measurements recorded at a resurvey from September 2013 to June 2014 were included. Data analysis was performed from July 1, 2016, to April 10, 2019. EXPOSURES: Major cardiovascular risk factors (ie, blood pressure [BP], blood lipid levels, smoking, and diabetes). MAIN OUTCOMES AND MEASURES: Carotid ultrasonographic measures of plaque burden (derived from number and maximum size of carotid artery plaques at resurvey) and first ischemic stroke during follow-up (n = 952), with subtyping (data release, August 2018) as lacunar (n = 263), probable large artery (n = 193), probable cardioembolic (n = 66), or unconfirmed (n = 430). Associations between cardiovascular risk factors, carotid plaque burden, and ischemic stroke subtypes were adjusted for age, sex, and geographic area. RESULTS: The 23 973 participants in the study had a mean (SD) age of 50.6 (10.0) years, and 14 833 (61.9%) were women. Systolic BP had a stronger association (odds ratio [OR] per SD, 1.51; 95% CI, 1.42-1.61) than plaque burden (OR per SD, 1.34; 95% CI, 1.26-1.44) with ischemic stroke, and the associations of systolic BP with each subtype of ischemic stroke were modestly attenuated by adjustment for plaque burden. After adjustment for BP, plaque burden had a stronger association with probable large artery stroke (OR, 1.43; 95% CI, 1.24-1.63) than with lacunar stroke (OR, 1.25; 95% CI, 1.10-1.43) but was not associated with probable cardioembolic stroke (OR, 1.06; 95% CI, 0.83-1.36). CONCLUSIONS AND RELEVANCE: Although BP was an important risk factor for all ischemic stroke subtypes, carotid atherosclerosis was an important risk factor only for large artery and lacunar strokes, suggesting that drug treatments targeting atherosclerosis may reduce the risk of stroke subtypes to different extents.

Published
2019

149. Investigating the global prevalence and consequences of undiagnosed stage 3 chronic kidney disease: methods and rationale for the REVEAL-CKD study.

Author

Kushner, Pamela, Peach, Emily, Wittbrodt, Eric, Barone, Salvatore, Chen, Hungta, Sanchez, Juan Jose Garcia, Järbrink, Krister, Arnold, Matthew, and Tangri, Navdeep

Subjects
CHRONIC kidney failure, KIDNEY failure, GLOMERULAR filtration rate, NOSOLOGY
Abstract

Background Timely diagnosis and treatment of stage 3 chronic kidney disease (CKD) can prevent further loss of kidney function and progression to kidney failure. However, contemporary data on the global prevalence of undiagnosed stage 3 CKD are scarce. REVEAL-CKD is a multinational, multifocal and observational study aiming to provide insights into undiagnosed stage 3 CKD in a large population. Methods Patients (aged ≥18 years) with data in selected secondary databases from 11 countries will be included if they have at least two estimated glomerular filtration rate (eGFR) measurements from 2015 onwards that are ≥30 and <60 mL/min/1.73 m2, recorded >90 and ≤730 days apart. Undiagnosed cases are those without an International Classification of Diseases 9/10 diagnosis code for CKD (any stage) any time before and up to 6 months after the second qualifying eGFR measurement. Time to diagnosis will be assessed using a Kaplan–Meier approach; patient characteristics associated with undiagnosed CKD will be assessed using adjusted logistical regression analyses. Results REVEAL-CKD will assess the point prevalence of undiagnosed stage 3 CKD and time to CKD diagnosis in initially undiagnosed cases overall and in individual countries. Trends in undiagnosed CKD prevalence by calendar year will be assessed. Patient characteristics, healthcare resource utilization, adverse clinical outcomes, and CKD management and monitoring practices in patients with versus without a CKD diagnosis will be compared. Conclusions REVEAL-CKD will increase awareness of the global clinical and economic burden of undiagnosed stage 3 CKD and provide valuable insights to inform clinical practice and policy changes. [ABSTRACT FROM AUTHOR]

Published
2022
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