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102. Fast-track Surgery Protocol for Hepatectomy and the Rate of Surgical Site Infections: A Single-center Study

Author

ENAMI, Yuta, AOKI, Takeshi, KUSANO, Tomokazu, NOGAKI, Koji, MATSUDA, Kazuhiro, YAMADA, Kosuke, KOIZUMI, Tomotake, MITAMURA, Keitaro, FUJIMORI, Akira, KOIKE, Reiko, GOTO, Satoru, WATANABE, Makoto, OTSUKA, Koji, and MURAKAMI, Masahiko

Abstract

The fast-track surgery protocol, including perioperative immunonutritional management, is increasingly gaining attention for the prevention of surgical site infections （SSIs）. To analyze the association between the fast-track surgery protocol employed at a single center and outcomes, including SSIs and the length of hospital stays. This retrospective analysis included 217 patients who underwent hepatectomy at the study department between January 2009 and February 2014. Patients were divided into two groups: those managed by a conventional protocol （group C, n＝75） and those managed by the fast-track surgery protocol （group F, n＝142）. There were no significant differences in patient characteristics or factors between the two groups. However, serum albumin and total cholesterol levels before surgery were significantly higher in group F than in group C, and pre-hepatectomy C-reactive protein （CRP） levels were lower in group F than in group C. Moreover, serum albumin and CRP levels at postoperative day 7 were better in group F than in group C. The operations were longer in group F than in group C （312 vs. 286 min） and blood loss volume was less （385 g in group F vs. 428 g in group C）. SSI rates were significantly lower in group F （4.2％, n＝6） than in group C （13.3％, n＝10）, and the length of hospital stay was significantly shorter in group F （16.7 days） than in group C （25.8 days）. The fast-track surgery protocol as a perioperative management strategy may improve preoperative nutritional status and postoperative inflammation, with subsequent reductions in SSI rates and the length of hospital stay in patients undergoing hepatectomy.

Published
2020

103. The Prognosis for Unexpected Gallbladder Carcinoma with Bile Spillage during Laparoscopic Cholecystectomy

Author

KOIZUMI, Tomotake, AOKI, Takeshi, ENAMI, Yuta, FUJIMORI, Akira, KUSANO, Tomokazu, MATSUDA, Kazuhiro, YAMADA, Kosuke, NOGAKI, Koji, TASHIRO, Yoshihiko, and MURAKAMI, Masahiko

Subjects
urologic and male genital diseases
Abstract

Here we review the prognosis of patients with unsuspected gallbladder carcinoma（GBC）, detected after laparoscopic cholecystectomy（LC）in a single institute. We reviewed the medical records of patients diagnosed with gallbladder stones on admission, who underwent LC. Carcinoma involving the gallbladder was found in 22 of 2,770 patients（0.9％）via postoperative pathological examination. This GBC group spanned 58-87 years of age（mean, 75 years; 13 females and 9 males）. The preoperative diagnosis was gallbladder stones with acute/chronic cholecystitis or adenomyomatosis of the gallbladder in all patients. We performed an additional surgery in 6 of 15 patients with pT2 and T3 disease; of these, 3 patients with pT2 disease and 1 with pT3 experienced bile spillage during the LC. The mean survival of patients with unexpected GBC was 21 months, with bile spillage occurring as a complication of LC identified as a potential risk factor for shorter survival（15.3 vs. 32.5 months）. We identified patients with pT2 and pT3 disease after LC, and two patients with pT2 and 1 with pT3 who had bile spillage during LC died of peritoneal dissemination within 28 months, despite additional surgery. Occasional seeding caused by bile spillage during LC should be carefully avoided to minimize the risk of developing unsuspected GBC after LC.

Published
2019

104. The Surgical Benefits of Repeat Hepatectomy for Colorectal Liver Metastasis

Author

KUSANO, Tomokazu, AOKI, Takeshi, YAMAZAKI, Tatsuya, HIRAI, Takashi, TOMIOKA, Koudai, SHIBATA, Hideki, WADA, Yuusuke, HAKOZAKI, Tomoki, TASHIRO, Yoshihiko, NOGAKI, Kouji, MATSUDA, Kazuhiro, YAMADA, Kousuke, KOIZUMI, Tomotake, MITAMURA, Keitaro, FUJIMORI, Akira, KOIKE, Reiko, ENAMI, Yuta, and MURAKAMI, Masahiko

Abstract

The most common site of distant metastasis from colorectal cancer is the liver, and hepatectomy presents the best curative treatment for recurrence of colorectal liver metastasis （CRLM）. This study aimed to identify factors of prognostic value for repeat hepatectomy for CRLM and to determine whether a third such procedure could similarly produce favourable outcomes for CRLM. We analyzed data for 161 patients in our department with colorectal metastasis. Of these, 22 patients underwent repeat hepatectomy for recurrent metastasis, with 16 undergoing a second hepatectomy and 6 a third hepatectomy. We analyzed patient characteristics, tumor status, operation-related variables, and short- and long-term outcomes. Univariate analysis for repeat hepatectomy identified the following five prognostic risk factors: T factor （＞SE） of the primary cancer, number of tumors involved in the initial hepatectomy （＞5）, interval from first to second hepatectomy （＜1year）, number of tumors involved in second hepatectomy （＞3）, and post-operation time （＞30days）. By multivariate analysis, T factor （＞SE） of the primary cancer, number of tumors in the initial hepatectomy （＞5）, and number of tumors in the second hepatectomy （＞3） were independently associated with a worse survival after surgery for CRLM. Although surgical outcomes of the third hepatectomy were not compared with those of the first and second hepatectomy, there were no obvious differences, nor did the 1-, 3-, and 5-year survival rates differ significantly among the three groups. Repeat hepatectomy for CRLM could improve long-term survival. In addition, patients undergoing a third hepatectomy showed a similar survival benefit to those having one or two resections.

Published
2019

106. Determinative Structural Features Identified With Probe-based Confocal Endomicroscopy for the Accurate Diagnosis of Gallbladder Malignancy

Author

KOIZUMI, TOMOTAKE, primary, AOKI, TAKESHI, additional, YAMOCHI, TOSHIKO, additional, TASHIRO, YOSHIHIKO, additional, YAMAZAKI, TATSUYA, additional, KUSANO, TOMOKAZU, additional, MATSUDA, KAZUHIRO, additional, WADA, YUSUKE, additional, SHIBATA, HIDEKI, additional, SAITO, KAZUHIKO, additional, NOGAKI, KOJI, additional, HAKOZAKI, TOMOKI, additional, TOMIOKA, KODAI, additional, HIRAI, TAKAHITO, additional, FUJIMORI, AKIRA, additional, MANSOUR, DOAA A., additional, ABBAS GAHIN, AHMED ELEWA, additional, and HOFFMAN, ROBERT M., additional

Published
2021
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107. The Tokyo 2020 terminology of liver anatomy and resections: Updates of the Brisbane 2000 system

Author

Wakabayashi, Go, primary, Cherqui, Daniel, additional, Geller, David A., additional, Abu Hilal, Mohammed, additional, Berardi, Giammauro, additional, Ciria, Ruben, additional, Abe, Yuta, additional, Aoki, Takeshi, additional, Asbun, Horacio J., additional, Chan, Albert C. Y., additional, Chanwat, Rawisak, additional, Chen, Kuo‐Hsin, additional, Chen, Yajin, additional, Cheung, Tan To, additional, Fuks, David, additional, Gotohda, Naoto, additional, Han, Ho‐Seong, additional, Hasegawa, Kiyoshi, additional, Hatano, Etsuro, additional, Honda, Goro, additional, Itano, Osamu, additional, Iwashita, Yukio, additional, Kaneko, Hironori, additional, Kato, Yutaro, additional, Kim, Ji Hoon, additional, Liu, Rong, additional, López‐Ben, Santiago, additional, Morimoto, Mamoru, additional, Monden, Kazuteru, additional, Rotellar, Fernando, additional, Sakamoto, Yoshihiro, additional, Sugioka, Atsushi, additional, Yoshiizumi, Tomoharu, additional, Akahoshi, Keiichi, additional, Alconchel, Felipe, additional, Ariizumi, Shunichi, additional, Benedetti Cacciaguerra, Andrea, additional, Durán, Manuel, additional, Garcia Vazquez, Alain, additional, Golse, Nicolas, additional, Miyasaka, Yoshihiro, additional, Mori, Yasuhisa, additional, Ogiso, Satoshi, additional, Shirata, Chikara, additional, Tomassini, Federico, additional, Urade, Takeshi, additional, Wakabayashi, Taiga, additional, Nishino, Hitoe, additional, Hibi, Taizo, additional, Kokudo, Norihiro, additional, Ohtsuka, Masayuki, additional, Ban, Daisuke, additional, Nagakawa, Yuichi, additional, Ohtsuka, Takao, additional, Tanabe, Minoru, additional, Nakamura, Masafumi, additional, Tsuchida, Akihiko, additional, and Yamamoto, Masakazu, additional

Published
2021
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108. Comparison of Endotoxin Activity Assay and Various Biomarkers for Severity Assessment in Colorectal Perforation Patients

Author

Matsuda, Kazuhiro, primary, Aoki, Takeshi, additional, Watanabe, Makoto, additional, Tomioka, Kodai, additional, Tashiro, Yoshihiko, additional, Tomokazu, Kusano, additional, Koizumi, Tomotake, additional, Satoru, Goto, additional, Yamazaki, Kimiyasu, additional, Otsuka, Koji, additional, and Murakami, Masahiko, additional

Published
2021
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109. Minimally invasive anatomic liver resection: Results of a survey of world experts

Author

Morimoto, Mamoru, primary, Monden, Kazuteru, additional, Wakabayashi, Taiga, additional, Gotohda, Naoto, additional, Abe, Yuta, additional, Honda, Goro, additional, Abu Hilal, Mohammed, additional, Aoki, Takeshi, additional, Asbun, Horacio J., additional, Berardi, Giammauro, additional, Chan, Albert C.Y., additional, Chanwat, Rawisak, additional, Chen, Kuo‐Hsin, additional, Chen, Yajin, additional, Cherqui, Daniel, additional, Cheung, Tan To, additional, Ciria, Ruben, additional, Fuks, David, additional, Geller, David A., additional, Han, Ho‐Seong, additional, Hasegawa, Kiyoshi, additional, Hatano, Etsuro, additional, Itano, Osamu, additional, Iwashita, Yukio, additional, Kaneko, Hironori, additional, Kato, Yutaro, additional, Kim, Ji Hoon, additional, Liu, Rong, additional, López‐Ben, Santiago, additional, Rotellar, Fernando, additional, Sakamoto, Yoshihiro, additional, Sugioka, Atsushi, additional, Yoshizumi, Tomoharu, additional, Akahoshi, Keiichi, additional, Alconchel, Felipe, additional, Ariizumi, Shunichi, additional, Benedetti Cacciaguerra, Andrea, additional, Durán, Manuel, additional, García Vázquez, Alain, additional, Golse, Nicolas, additional, Miyasaka, Yoshihiro, additional, Mori, Yasuhisa, additional, Ogiso, Satoshi, additional, Shirata, Chikara, additional, Tomassini, Federico, additional, Urade, Takeshi, additional, Nishino, Hitoe, additional, Kunzler, Filipe, additional, Kozono, Shingo, additional, Osakabe, Hiroaki, additional, Takishita, Chie, additional, Ban, Daisuke, additional, Hibi, Taizo, additional, Kokudo, Norihiro, additional, Ohtsuka, Masayuki, additional, Nagakawa, Yuichi, additional, Ohtsuka, Takao, additional, Tanabe, Minoru, additional, Nakamura, Masafumi, additional, Yamamoto, Masakazu, additional, Tsuchida, Akihiko, additional, and Wakabayashi, Go, additional

Published
2021
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110. Expert Consensus Guidelines: How to safely perform minimally invasive anatomic liver resection

Author

Gotohda, Naoto, primary, Cherqui, Daniel, additional, Geller, David A., additional, Abu Hilal, Mohammed, additional, Berardi, Giammauro, additional, Ciria, Ruben, additional, Abe, Yuta, additional, Aoki, Takeshi, additional, Asbun, Horacio J., additional, Chan, Albert C. Y., additional, Chanwat, Rawisak, additional, Chen, Kuo‐Hsin, additional, Chen, Yajin, additional, Cheung, Tan To, additional, Fuks, David, additional, Han, Ho‐Seong, additional, Hasegawa, Kiyoshi, additional, Hatano, Etsuro, additional, Honda, Goro, additional, Itano, Osamu, additional, Iwashita, Yukio, additional, Kaneko, Hironori, additional, Kato, Yutaro, additional, Kim, Ji Hoon, additional, Liu, Rong, additional, López‐Ben, Santiago, additional, Morimoto, Mamoru, additional, Monden, Kazuteru, additional, Rotellar, Fernando, additional, Sakamoto, Yoshihiro, additional, Sugioka, Atsushi, additional, Yoshiizumi, Tomoharu, additional, Akahoshi, Keiichi, additional, Alconchel, Felipe, additional, Ariizumi, Shunichi, additional, Benedetti Cacciaguerra, Andrea, additional, Durán, Manuel, additional, Garcia Vazquez, Alain, additional, Golse, Nicolas, additional, Miyasaka, Yoshihiro, additional, Mori, Yasuhisa, additional, Ogiso, Satoshi, additional, Shirata, Chikara, additional, Tomassini, Federico, additional, Urade, Takeshi, additional, Wakabayashi, Taiga, additional, Nishino, Hitoe, additional, Hibi, Taizo, additional, Kokudo, Norihiro, additional, Ohtsuka, Masayuki, additional, Ban, Daisuke, additional, Nagakawa, Yuichi, additional, Ohtsuka, Takao, additional, Tanabe, Minoru, additional, Nakamura, Masafumi, additional, Yamamoto, Masakazu, additional, Tsuchida, Akihiko, additional, and Wakabayashi, Go, additional

Published
2021
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111. Clinical Treatment of Perioperative Disseminated Intravascular Coagulation in Patients Who Underwent Gastrointestinal and Hepato-Biliary-Pancreatic Surgery

Author

Tomioka, Kodai, primary, Aoki, Takeshi, additional, Matsuda, Kazuhiro, additional, Enami, Yuta, additional, Fujimori, Akira, additional, Koizumi, Tomotake, additional, Kusano, Tomokazu, additional, Date, Hiromi, additional, Yamashita, Takeshi, additional, Ariyoshi, Tomotake, additional, Goto, Satoru, additional, Yamazaki, Kimiyasu, additional, Watanabe, Makoto, additional, Otsuka, Koji, additional, and Murakami, Masahiko, additional

Published
2021
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112. Brief report: the smiles of a child with autism spectrum disorder during an animal-assisted activity may facilitate social positive behaviors--quantitative analysis with smile-detecting interface

Author

Funahashi, Atsushi, Gruebler, Anna, Aoki, Takeshi, Kadone, Hideki, and Suzuki, Kenji

Subjects
Pervasive developmental disorders -- Development and progression -- Social aspects, Face recognition (Psychology) -- Health aspects, Social perception -- Health aspects, Health
Abstract

We quantitatively measured the smiles of a child with autism spectrum disorder (ASD-C) using a wearable interface device during animal-assisted activities (AAA) for 7 months, and compared the results with a control of the same age. The participant was a 10-year-old boy with ASD, and a normal healthy boy of the same age was the control. They voluntarily participated in this study. Neither child had difficulty putting on the wearable device. They kept putting on the device comfortably through the entire experiment (duration of a session was about 30-40 min). This study was approved by the Ethical Committee based on the rules established by the Institute for Developmental Research, Aichi Human Service Center. The behavior of the participants during AAA was video-recorded and coded by the medical examiner (ME). In both groups, the smiles recognized by the ME corresponded with the computer-detected smiles. In both groups, positive social behaviors increased when the smiles increased. Also, negative social behaviors decreased when the smiles increased in the (ASD-C). It is suggested that by leading the (ASD-C) into a social environment that may cause smiling, the child's social positive behaviors may be facilitated and his social negative behaviors may be decreased. Keywords Autism spectrum disorder * Animal-assisted activity * Smile-detecting interface, Introduction It is generally accepted that autism spectrum disorder (ASD) is a group of developmental brain disorders. Children with ASD have core features such as delays in social interaction and [...]

Published
2014
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113. 67 STRATEGY FOR DEFINITIVE TREATMENT AND PRESERVING QUALITY OF LIFE IN UPPER CERVICAL ESOPHAGEAL CARCINOMA

Author

Goto, Satoru, primary, Koji, Otsuka, additional, Fujimasa, Koichiro, additional, Saito, Akira, additional, Komoto, Masahiro, additional, Kato, Rei, additional, Motegi, Kentaro, additional, Watanabe, Ryohei, additional, Date, Hiromi, additional, Yamashita, Takeshi, additional, Ariyoshi, Tomotake, additional, Yamazaki, Kimiyasu, additional, Aoki, Takeshi, additional, and Murakami, Masahiko, additional

Published
2021
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114. Indocyanine Green Fluorescence Image-guided Laparoscopic Hepatectomy Enabled Resection of a Tumor Invisible With Ultrasonography

Author

OURA, KEISUKE, primary, AOKI, TAKESHI, additional, TASHIRO, YOSHIHIKO, additional, MATSUDA, KAZUHIRO, additional, KOIZUMI, TOMOTAKE, additional, KUSANO, TOMOKAZU, additional, WADA, YUSUKE, additional, SHIBATA, HIDEKI, additional, YAMASHITA, TAKESHI, additional, DATE, HIROMI, additional, ARIYOSHI, TOMOTAKE, additional, GOTO, SATORU, additional, YAMAZAKI, KIMIYASU, additional, WATANABE, MAKOTO, additional, FUJIMORI, AKIRA, additional, ENAMI, YUTA, additional, OTSUKA, KOJI, additional, HOFFMAN, ROBERT M., additional, and MURAKAMI, MASAHIKO, additional

Published
2021
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117. 5 - R&D on commercial high temperature gas-cooled reactor

Author

Aihara, Jun, Aoki, Takeshi, Fukaya, Yuji, Goto, Minoru, Imai, Yoshiyuki, Inaba, Yoshitomo, Inagaki, Yoshiyuki, Iyoku, Tatsuo, Kamiji, Yu, Kasahara, Seiji, Kubo, Shinji, Kunitomi, Kazuhiko, Mizuta, Naoki, Myagmarjav, Odtsetseg, Nishihara, Tetsuo, Noguchi, Hiroki, Ohashi, Hirofumi, Sakaba, Nariaki, Sasaki, Koei, Sato, Hiroyuki, Shibata, Taiju, Sumita, Junya, Tachibana, Yukio, Takada, Shoji, Takeda, Tetsuaki, Takegami, Hiroaki, Tanaka, Nobuyuki, Ueta, Shohei, and Yan, Xing

Published
2021
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118. Impacts of 240Pu self-shielding effect and uncertainties of σ(n,γ) at resonance energy on the reactivity controllability in HTGR inert matrix fuel

Author

Aoki, Takeshi, SAGARA, Hiroshi, HAN, CHI YOUNG, and HAN, Chi Young

Subjects
Inert, Materials science, 020209 energy, Self-shielding, Thermodynamics, Resonance, TRISO, 02 engineering and technology, General Medicine, Self shielding, Plutonium, Controllability, Matrix (mathematics), HTGR, Deep Burn, 0202 electrical engineering, electronic engineering, information engineering, Reactivity (chemistry), MVP, Energy (signal processing)
Published
2018

119. Comparison of Endotoxin Activity Assay and Various Biomarkers for Severity Assessment in Colorectal Perforation Patients.

Author

Matsuda, Kazuhiro, Aoki, Takeshi, Watanabe, Makoto, Tomioka, Kodai, Tashiro, Yoshihiko, Tomokazu, Kusano, Koizumi, Tomotake, Satoru, Goto, Yamazaki, Kimiyasu, Otsuka, Koji, and Murakami, Masahiko

Subjects
*ENDOTOXINS, *INTENSIVE care patients, *BIOMARKERS, *SURGICAL emergencies
Abstract

Colorectal perforation is a serious disease with high mortality requiring emergency surgery. This study aimed to evaluate the role of the endotoxin activity assay (EAA) to assess the severity in patients admitted to the intensive care unit after emergency surgeries for colorectal perforations. Patients were divided into high (EAA ≥.4) and low (EAA <.4) groups based on the EAA levels, and the correlation between the EAA values and clinical variables related to the severity was evaluated. The SOFA scores were significantly higher in the high group than those in the low group. The high EAA value persisted even after 48 hours and extended the ICU length of stay. These results suggest that EAA may be a potential biomarker to assess severity and useful as one of the instrumental in predicting the outcomes for colorectal perforation patients. [ABSTRACT FROM AUTHOR]

Published
2023
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120. Laparoscopic Resection of a Hepatic Epithelioid Angiomyolipoma Revealed by Indocyanine Green Fluorescence Imaging.

Author

Mochizuki, Kiyotaka, Aoki, Takeshi, Kusano, Tomokazu, Tomioka, Kodai, Tashiro, Yoshihiko, Koizumi, Tomotake, Matsuda, Kazuhiro, Enami, Yuta, Yamochi, Toshiko, and Murakami, Masahiko

Subjects
*LAPAROSCOPIC surgery, *INDOCYANINE green, *SURGICAL margin, *ANGIOMYOLIPOMA, *LIVER tumors
Abstract

Indocyanine green fluorescence imaging (ICG-FI)—a sensitive tool for detecting tumor localization in laparoscopic surgery—produces false positive results for benign liver tumors. This report is the first case of hepatic angiomyolipoma (HAML) treated laparoscopically with ICG-FI. We present the case of a 31-year-old woman with a liver tumor that was a 13-mm mass in the anterior superior segment. Though a benign tumor was suspected, malignant potential could not be ruled out. Therefore, minimally invasive laparoscopic resection using ICG-FI was planned. ICG, intravenously injected preoperatively, revealed the tumor's existence. Pure laparoscopic hepatectomy with ICG-FI was performed for excisional biopsy, during which the tumor was resected with adequate surgical margins, followed by histological confirmation of HAML. In conclusion, it is suggested that laparoscopic resection with ICG-FI is an effective minimal invasive surgery for tumors that are difficult to detect, such as HAML, leading to a safe surgical margin. [ABSTRACT FROM AUTHOR]

Published
2023
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121. A snapshot of the 2020 conception of anatomic liver resections and their applicability on minimally invasive liver surgery. A preparatory survey for the Expert Consensus Meeting on Precision Anatomy for Minimally Invasive HBP Surgery

Author

Ciria, Ruben, Berardi, Giammauro, Nishino, Hitoe, Chan, Albert C.Y., Chanwat, Rawisak, Chen, Kuo‐Hsin, Chen, Yajin, Cheung, Tan To, Fuks, David, Geller, David, Iwashita, Yukio, Liu, Rong, López‐Ben, Santiago, Yamamoto, Masakazu, Wakabayashi, Go, Abe, Yuta, Abu Hilal, Mohammed, Aoki, Takeshi, Asbun, Horacio, Cherqui, Daniel, Gotohda, Naoto, Han, Ho‐Seong, Hasegawa, Kiyoshi, Hatano, Etsuro, Honda, Goro, Itano, Osamu, Kato, Yutaro, Kaneko, Hironori, Kim, Ji Hoon, Monden, Kazuteru, Morimoto, Mamoru, Rotellar, Fernando, Sakamoto, Yoshihiro, Sugioka, Atsushi, Tanabe, Minoru, Yoshizumi, Tomoharu, Akahoshi, Keiichi, Ariizumi, Shunichi, Benedetti Cacciaguerra, Andrea, Duran, Manuel, Alconchel Gago, Felipe, Golse, Nicolas, Miyasaka, Yoshihiro, Mori, Yasuhisa, Ogiso, Satoshi, Shirata, Chikara, Tomassini, Federico, Urade, Takeshi, García Vázquez, Alain, Wakabayashi, Taiga, Endo, Itaru, Tsuchida, Akihiko, Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and Université de Paris (UP)

Subjects
Liver surgery, medicine.medical_specialty, Consensus, [SDV]Life Sciences [q-bio], Liver resections, Resection, 03 medical and health sciences, 0302 clinical medicine, medicine, Hepatectomy, Humans, Minimally Invasive Surgical Procedures, Anatomic resection, ComputingMilieux_MISCELLANEOUS, Hepatology, business.industry, General surgery, Liver Neoplasms, Expert consensus, Portal vein flow, Congresses as Topic, 3. Good health, Liver anatomy, 030220 oncology & carcinogenesis, Hepatic veins, 030211 gastroenterology & hepatology, Surgery, Laparoscopy, business
Abstract

BACKGROUND The main aim of this survey was to analyze how liver surgeons perform liver resections and to define their conception of anatomic procedures within the incorporation of minimally invasive liver surgery (MILS). METHODS The survey was distributed among liver surgeons. It mainly focused on personal experience on open and MILS, methods and landmarks, and experience on anatomic resections and Glissonean approach. RESULTS A total of 445 valid answers from 54 countries was obtained. Surgeons performing MILS mainly have below 10 years of experience (81.8% of responders) and one third has never done complex MILS. New techniques, including indocyanine green demarcation are marginally used (

Published
2021

122. Additional file 1 of Increased neutrophil–lymphocyte ratio predicts recurrence in patients with well-differentiated pancreatic neuroendocrine neoplasm based on the 2017 World Health Organization classification

Author

Miura, Takayuki, Ohtsuka, Hideo, Aoki, Takeshi, Aoki, Shuichi, Hata, Tatsuo, Takadate, Tatsuyuki, Maeda, Shimpei, Ariake, Kyohei, Kawaguchi, Kei, Masuda, Kunihiro, Ishida, Masaharu, Mizuma, Masamichi, Nakagawa, Kei, Morikawa, Takanori, Fumiyoshi Fujishima, Kamei, Takashi, Sasano, Hironobu, and Unno, Michiaki

Subjects
fungi
Abstract

Additional file 1: Fig. S1. ROC curve for the NLR and tumor size in well-differentiated PanNENs. The ROC curve illustrated that NLR has an AUC of 0.664 (95% CI 0.464–0.864) and tumor size has an AUC of 0.801 (95% CI 0.675–0.945). Arrows indicate optimal cut-off values. Fig. S2. Recurrence-free-survival and overall survival for PanNENs stratified by the 2017 WHO classification. Recurrence-free-survival and overall survival of neuroendocrine carcinoma (NEC) were significantly shorter than those of well-differentiated PanNENs (NET G1-3). Fig. S3. Distribution of NLR in PanNENs stratified by the 2017 WHO classification. The value of NLR in patients with NEC was significantly higher than that in patients with well-differentiated PanNEN.

Published
2021
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124. Safety of Combined Division vs Separate Division of the Splenic Vein in Patients Undergoing Distal Pancreatectomy

Author

Yamada, Suguru, primary, Fujii, Tsutomu, additional, Sonohara, Fuminori, additional, Kawai, Manabu, additional, Shibuya, Kazuto, additional, Matsumoto, Ippei, additional, Fukuzawa, Kengo, additional, Baba, Hideo, additional, Aoki, Takeshi, additional, Unno, Michiaki, additional, Satoi, Sohei, additional, Kishi, Yoji, additional, Hatano, Etsuro, additional, Uemura, Kenichiro, additional, Horiguchi, Akihiko, additional, Sho, Masayuki, additional, Takeda, Yutaka, additional, Shimokawa, Toshio, additional, Kodera, Yasuhiro, additional, and Yamaue, Hiroki, additional

Published
2021
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126. Use of Transumbilical Incision as an Organ Removal Site in Laparoscopic Pancreatectomy

Author

TOMIOKA, KODAI, primary, MURAKAMI, MASAHIKO, additional, AOKI, TAKESHI, additional, MATSUDA, KAZUHIRO, additional, KOIZUMI, TOMOTAKE, additional, KUSANO, TOMOKAZU, additional, NOGAKI, KOJI, additional, TASHIRO, YOSHIHIKO, additional, WADA, YUSUKE, additional, HAKOZAKI, TOMOKI, additional, SHIBATA, HIDEKI, additional, HIRAI, TAKAHITO, additional, YAMAZAKI, TATSUYA, additional, SAITO, KAZUHIKO, additional, SATO, YOSHIHITO, additional, MOCHIZUKI, KIYOTAKA, additional, FUJIMORI, AKIRA, additional, and ENAMI, YUTA, additional

Published
2021
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127. Blood Pressure Level and Variability During Long-Term Prasugrel or Clopidogrel Medication After Stroke

Author

Toyoda, Kazunori, primary, Yamagami, Hiroshi, additional, Kitagawa, Kazuo, additional, Kitazono, Takanari, additional, Nagao, Takehiko, additional, Minematsu, Kazuo, additional, Uchiyama, Shinichiro, additional, Tanahashi, Norio, additional, Matsumoto, Masayasu, additional, Nagata, Izumi, additional, Nishikawa, Masakatsu, additional, Nanto, Shinsuke, additional, Shirai, Toshiaki, additional, Abe, Kenji, additional, Ikeda, Yasuo, additional, Ogawa, Akira, additional, Ozaki, Yukio, additional, Go, Yoshinori, additional, Gi, Hidefuku, additional, Furui, Eisuke, additional, Kosaka, Satoru, additional, Uenohara, Hiroshi, additional, Fukuyama, Kozo, additional, Maruki, Chikashi, additional, Takenaka, Katsunobu, additional, Ogiichi, Tsuneaki, additional, Matsushima, Kazushi, additional, Osaki, Masato, additional, Nakagawa, Hidemitsu, additional, Aoki, Michio, additional, Sakai, Nobuyuki, additional, Kuroki, Kazuhiko, additional, Mori, Takahisa, additional, Uno, Eiichi, additional, Terasaki, Tadashi, additional, Metoki, Norifumi, additional, Naka, Takashi, additional, Ohnishi, Hideyuki, additional, Koyama, Hideki, additional, Ogihara, Kotaro, additional, Kiriyama, Hideki, additional, Oki, Shuuichi, additional, Murao, Kei, additional, Matsumoto, Masahiro, additional, Suzuki, Kazunari, additional, Saito, Shinjiro, additional, Suda, Sumio, additional, Sadatomo, Takashi, additional, Miyake, Hiroji, additional, Itamoto, Kouji, additional, Fujita, Keishi, additional, Ohashi, Toshihiko, additional, Ito, Hiroki, additional, Ito, Yasuhiro, additional, Dehara, Makoto, additional, Hitotsumatsu, Tsutomu, additional, Hirose, Makoto, additional, Nakagaki, Yusuke, additional, Takemura, Sunao, additional, Tomimitsu, Hiroyuki, additional, Izuta, Makoto, additional, Mekaru, Susumu, additional, Kin, Shigenari, additional, Akaike, Yuji, additional, Miyatake, Masaki, additional, Wada, Naomichi, additional, Shibata, Norio, additional, Koyama, Kazuo, additional, Ichikawa, Yasumitsu, additional, Torii, Tsuyoshi, additional, Nakane, Hiroshi, additional, Kobayashi, Yasushi, additional, Kida, Shinya, additional, Nishino, Shigeki, additional, Tabata, Hitoshi, additional, Sano, Motoki, additional, Fuｊigasaki, Hiroto, additional, Nagatsuka, Kazuyuki, additional, Koga, Masatoshi, additional, Fujita, Hitoshi, additional, Yasaka, Masahiro, additional, Nakahara, Kimihiro, additional, Tomiyama, Masahiko, additional, Fujita, Tsuneo, additional, Hoshi, Seiichiro, additional, Ota, Takahiro, additional, Orimo, Satoshi, additional, Momose, Yoshio, additional, Yamashita, Katsuhiro, additional, Shingaki, Tatsuya, additional, Kaku, Yasuhiko, additional, Terasawa, Hideo, additional, Kawamoto, Yukihiko, additional, Tokunaga, Yoshiharu, additional, Chiba, Kei, additional, Okada, Yoshio, additional, Yanai, Yoshimi, additional, Sato, Atsushi, additional, Miake, Hirotomo, additional, Imai, Shu, additional, Morimoto, Masanori, additional, Nunomura, Mitsuru, additional, Irie, Shinsuke, additional, Konno, Shu, additional, Kanzawa, Takao, additional, Hayase, Makoto, additional, Yoshino, Kimihiro, additional, Izumidani, Tomohiko, additional, Kanda, Masutaro, additional, Kurokawa, Shinichiro, additional, Kawada, Sanami, additional, Takase, Keiichiro, additional, Takashima, Hiroshi, additional, Haraguchi, Koichi, additional, Murai, Hiroshi, additional, Suzuki, Mikio, additional, Shimohata, Mitsuteru, additional, Takeuchi, Shigekazu, additional, Asakura, Ken, additional, Seguchi, Tatsuya, additional, Toba, Yasuyuki, additional, Nitta, Eishun, additional, Moriki, Akihito, additional, Koan, Yoko, additional, Kaneko, Yoshiro, additional, Suzuki, Hisahiko, additional, Yoshida, Yasumasa, additional, Naka, Yutaka, additional, Katayama, Shinji, additional, Imamura, Eiji, additional, Kazekawa, Kiyoshi, additional, Yu, Iwae, additional, Satoh, Akira, additional, Maruyama, Junichi, additional, Takahashi, Akira, additional, Arimoto, Hirohiko, additional, Hasegawa, Yasuhiro, additional, Fukazawa, Seiji, additional, Nishimura, Yasuaki, additional, Yamada, Tomonori, additional, Tsuji, Tetsuro, additional, Wakayama, Akatsuki, additional, Murao, Kenichi, additional, Tominaga, Atsushi, additional, Takaba, Hitonori, additional, Shimazaki, Mitsunori, additional, Ishibashi, Yasuhiro, additional, Oguni, Eiichi, additional, Kuroyanagi, Takayuki, additional, Tanno, Hirokazu, additional, Kawada, Norikazu, additional, Hondo, Hideki, additional, Matsuoka, Hideki, additional, Umemura, Toshitaka, additional, Hazama, Takanori, additional, Nishio, Masami, additional, Kawaba, Tomoyuki, additional, Wada, Hirochiyo, additional, Kamitsukasa, Ikuo, additional, Endo, Sumio, additional, Ueda, Toshihiro, additional, Narumi, Osamu, additional, Ino, Tadashi, additional, Yamada, Takeshi, additional, Urabe, Takao, additional, Ota, Koichi, additional, Kato, Tokunori, additional, Nomura, Kyoichi, additional, Ieda, Toshiaki, additional, Kagawa, Masahiro, additional, Mizota, Takamitsu, additional, Sueyoshi, Kenji, additional, Nakajima, Yoshikazu, additional, Fujita, Toshiaki, additional, Teramoto, Yoshifumi, additional, Mori, Katsuharu, additional, Takaya, Satoru, additional, Uemura, Kazuya, additional, Inukai, Akira, additional, Kubo, Michiya, additional, Takahashi, Ryoichi, additional, Takahashi, Tsutomu, additional, Kawauchi, Masamitsu, additional, Hirahara, Kazuho, additional, Matsumoto, Sadayuki, additional, Masuo, Osamu, additional, Nishi, Shinsuke, additional, Niwa, Jun, additional, Kubo, Naohiko, additional, Yamamoto, Kanji, additional, Watanabe, Sadayoshi, additional, Okuda, Satoshi, additional, Okamoto, Kensho, additional, Masago, Atsuo, additional, Ohuchi, Masafumi, additional, Harada, Kunihiko, additional, Hashimoto, Yoichiro, additional, Hayashi, Kentaro, additional, Fujita, Nobuya, additional, Mori, Shuichi, additional, Sakaguchi, Manabu, additional, Noda, Kosumo, additional, Aoki, Takeshi, additional, Nakase, Taizen, additional, Shibuya, Satoshi, additional, Kamei, Satoshi, additional, Kanbayashi, Chisaku, additional, Hattori, Naoyuki, additional, Takashima, Shutaro, additional, Manabe, Yasuhiro, additional, Kobayashi, Nobuaki, additional, Takano, Katsunobu, additional, Ajiki, Minoru, additional, Kondo, Yoshiyuki, additional, Hashikawa, Kazuo, additional, Ikezoe, Koji, additional, Morita, Mitsuya, additional, Sakai, Keiichi, additional, Toi, Sono, additional, Iwamura, Makoto, additional, Takeuchi, Juji, additional, Suenaga, Toshihiko, additional, Takao, Masaki, additional, Kimura, Takashi, additional, Ozaki, Akihiko, additional, Kadekaru, Tsutomu, additional, Kato, Tsutomu, additional, Yamashita, Kosuke, additional, Ago, Tetsuro, additional, Tamaru, Shinichi, additional, Sekijima, Yoshiki, additional, Ito, Hisashi, additional, Yamasaki, Masahiro, additional, Kawai, Hiromichi, additional, Imai, Keisuke, additional, Sekine, Tomoyuki, additional, Inoya, Hiroshi, additional, Sawada, Motoshi, additional, Mano, Kazuo, additional, Sonoo, Masahiro, additional, and Ikeda, Masaki, additional

Published
2021
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128. The Efficacy of Intraoperative Fluorescent Imaging Using Indocyanine Green for Cholangiography During Cholecystectomy and Hepatectomy

Author

Shibata, Hideki, primary, Aoki, Takeshi, additional, Koizumi, Tomotake, additional, Kusano, Tomokazu, additional, Yamazaki, Tatsuya, additional, Saito, Kazuhiko, additional, Hirai, Takahito, additional, Tomioka, Kodai, additional, Wada, Yusuke, additional, Hakozaki, Tomoki, additional, Tashiro, Yoshihiko, additional, Nogaki, Koji, additional, Yamada, Kosuke, additional, Matsuda, Kazuhiro, additional, Fujimori, Akira, additional, Enami, Yuta, additional, and Murakami, Masahiko, additional

Published
2021
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143. Development of Flexible Deformation Mobile Robot Composed of Multiple Units and Pneumatic Self-Excited Valve.

Author

Hada, Takuya, Iguchi, Kenta, and Aoki, Takeshi

Subjects
MOBILE robots, LEAF springs, ELECTRONIC circuits, SOLENOIDS, AIRDROP
Abstract

In this study, we developed new bending modules and pneumatic self-excited valves. In a previous study, we developed a planar flexible-deformation mobile robot that combines multiple bending modules. The robot moves by a traveling wave, which is periodically generated by pressurizing air to the bending modules. Further, it can move in every direction by simultaneously combining the two directional traveling waves. However, problems such as air leakage from the bending module that constitutes the moving object and the influence of the moving operation owing to the tubes comprising the flow path were identified. To address these problems, new bending modules have been developed. To address air leak issues, we verified the materials used in the bending modules and developed an injection mechanism. To reduce the number of externally connected tubes, we developed new bending modules that could include multiple internal flow paths. In addition, because the mobile robot moves owing to the generation of traveling waves, it is a low-grade operation. However, this requires multiple solenoid valves and electronic circuits. This is useful if traveling waves can be generated by simply supplying air using a pneumatic self-excited valve. In this study, we developed bending modules with multiple internal channels and a pneumatic self-excited valve that utilizes the snap buckling of leaf springs used in the mobile robot. [ABSTRACT FROM AUTHOR]

Published
2022
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144. Tumoral calcinosis due to severe hyperphosphatemia and secondary hyperparathyroidism without vascular calcification in a hemodialysis patient

Author

Saito, Tomohiro, primary, Mizobuchi, Masahide, additional, Hamada, Toma, additional, Sugiyama, Motonori, additional, Miyazawa, Nozomi, additional, Morikawa, Tomoki, additional, Matsumoto, Kei, additional, Yoshitake, Osamu, additional, Aoki, Takeshi, additional, Murakami, Masahiko, additional, and Honda, Hirokazu, additional

Published
2021
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145. The Prognostic Impact of Eosinophils and the Eosinophil-to-Lymphocyte Ratio on Survival Outcomes in Stage II Resectable Pancreatic Cancer

Author

Ohkuma, Ryotaro, primary, Kubota, Yutaro, additional, Horiike, Atsushi, additional, Ishiguro, Tomoyuki, additional, Hirasawa, Yuya, additional, Ariizumi, Hirotsugu, additional, Watanabe, Makoto, additional, Onoue, Rie, additional, Ando, Kiyohiro, additional, Tsurutani, Junji, additional, Yoshimura, Kiyoshi, additional, Aoki, Takeshi, additional, Murakami, Masahiko, additional, Kobayashi, Shinichi, additional, Tsunoda, Takuya, additional, and Wada, Satoshi, additional

Published
2021
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146. Intraoperative Shear Wave Elastography as a Quantitative Predictor of Pancreatic Fibrosis and Exocrine Function

Author

WADA, YUSUKE, primary, AOKI, TAKESHI, additional, FUJIMORI, AKIRA, additional, OHIKE, NOBUYUKI, additional, KOIZUMI, TOMOTAKE, additional, KUSANO, TOMOKAZU, additional, MATSUDA, KAZUHIRO, additional, NOGAKI, KOJI, additional, TASHIRO, YOSHIHIKO, additional, HAKOZAKI, TOMOKI, additional, SHIBATA, HIDEKI, additional, TOMIOKA, KODAI, additional, HIRAI, TAKAHITO, additional, SAITO, KAZUHIKO, additional, YAMAZAKI, TATSUYA, additional, and MURAKAMI, MASAHIKO, additional

Published
2021
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147. Relationship Between Remnant Pancreatic Volume and Endocrine Function After Pancreaticoduodenectomy

Author

Yamazaki, Tatsuya, primary, Aoki, Takeshi, additional, Tashiro, Yoshihiko, additional, Koizumi, Tomotake, additional, Kusano, Tomokazu, additional, Matsuda, Kazuhiro, additional, Fujimori, Akira, additional, Yamada, Kosuke, additional, Nogaki, Koji, additional, Hakozaki, Tomoki, additional, Wada, Yusuke, additional, Shibata, Hideki, additional, Tomioka, Kodai, additional, Enami, Yuta, additional, and Murakami, Masahiko, additional

Published
2021
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149. Liver Transection with Precoagulation Therapy in Liver Cirrhosis: Effective Use of an Energy Device at Hepatectomy

Author

Kusano, Tomokazu, primary, Aoki, Takeshi, additional, Koizumi, Tomotake, additional, Matsuda, Kazuhiro, additional, Yamada, Kosuke, additional, Nogaki, Koji, additional, Tashiro, Yoshihiko, additional, Wada, Yusuke, additional, Hakozaki, Tomoki, additional, Shibata, Hideki, additional, Tomioka, Kodai, additional, Hirai, Takahito, additional, Yamazaki, Tatsuya, additional, Saito, Kazuhiko, additional, Mitamura, Keitaro, additional, Fujimori, Akira, additional, Koike, Reiko, additional, Enami, Yuta, additional, and Murakami, Masahiko, additional

Published
2021
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