575 results on '"Ann Campbell"'
Search Results
102. Informing Police Response to Intimate Partner Violence: Predictors of Perceived Usefulness of Risk Assessment Screening
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Mary Ann Campbell, Carmen Gill, and Dale Ballucci
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medicine.medical_specialty ,education ,05 social sciences ,Poison control ,Human factors and ergonomics ,Risk management tools ,16. Peace & justice ,Suicide prevention ,Occupational safety and health ,5. Gender equality ,Respondent ,050501 criminology ,medicine ,Domestic violence ,Psychiatry ,Risk assessment ,Psychology ,Law ,Applied Psychology ,0505 law ,Clinical psychology - Abstract
Substantial research has demonstrated the value of using risk assessment tools for the prediction and management of violence risk, including for intimate partner violence (IPV) (Mills, Kroner, and Morgan 2011). Such tools have been advocated for use by police officers (Hilton, Grant, and Rice 2010), but little is known about police officers’ perceptions of using these tools to inform their decision-making. Using a sample of 159 Canadian police officers (73% male, M age = 41.8 years, SD = 8.9), the current study examined police officer’s experiences with IPV risk tools, their attitudes about using such tools, and identified predictors of these attitudes using an online survey. Most of this sample had previously used an IPV risk tool, which was most commonly the Brief Spousal Assault Form for the Evaluation of Risk (64.1%). Most police officers rated use of risk tools as at least somewhat to extremely helpful (73.5%), and 67.4% indicated that they would use a risk tool with sufficient training on it. Regression analyses indicated that police officers’ perceived IPV risk tool usefulness was significantly predicted by older respondent age and greater perceived need for guidance in responding to IPV calls. In conclusion, most police officers view IPV risk screening as valuable for informing their responses to such calls for service and are likely to embrace such decision-aids with sufficient training on their potential impact for enhancing safety.
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- 2017
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103. Violence and abuse against people with disabilities: A comparison of the approaches of the European Court of Human Rights and the United Nations Committee on the Rights of Persons with Disabilities
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Oliver Lewis and Ann Campbell
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Human rights ,Institutionalisation ,Universal design ,media_common.quotation_subject ,Poison control ,030209 endocrinology & metabolism ,Criminology ,International law ,Pathology and Forensic Medicine ,03 medical and health sciences ,Psychiatry and Mental health ,0302 clinical medicine ,International human rights law ,Denial ,Political science ,Domestic violence ,030212 general & internal medicine ,Law ,media_common - Abstract
This paper explores how, and how effectively, two systems of international law have addressed exploitation, violence and abuse of people with mental disabilities. The two international systems reviewed were the Council of Europe's European Court of Human Rights and the United Nations Committee on the Rights of Persons with Disabilities. The two issues dealt with are (a) forced institutionalisation and denial of community-based services and (b) medically-sanctioned treatment as abuse or violence. The paper offers a comparative analysis of the way in which the two bodies have dealt with exploitation, violence and abuse of people with disabilities, and offers recommendations as to how the two bodies could adjust their approaches to come into closer alignment.
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- 2017
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104. Can the welfare state replace parents? Children's cognition in the United States and Great Britain
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Toby L. Parcel and Lori Ann Campbell
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030505 public health ,Multivariate analysis ,National Child Development Study ,Sociology and Political Science ,05 social sciences ,Cognition ,Welfare state ,Child health ,Education ,Developmental psychology ,03 medical and health sciences ,Low birth weight ,050902 family studies ,medicine ,0509 other social sciences ,medicine.symptom ,0305 other medical science - Abstract
We compare family and parental effects on child verbal facility, verbal achievement and mathematics achievement in the United States and Great Britain. We study 3,438 5-13 year-old children from the 1994 NLSY Child-Mother Data Set and 1429 same-aged children from the National Child Development Study, also known as the British Child. Multivariate analyses suggest that the processes through which families invest in child cognition are similar across societies, with factors including low birth weight, child health, maternal cognition, family size and children's home environments being consequential. We conclude that parental investments are equally important across the two societies. The more developed welfare state in Great Britain does not notably compensate for parental investments in that society, although it may play a greater role when parental resources are absent or stretched thin.
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- 2017
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105. The Power of Attitude: The Role of Police Culture and Receptivity of Risk Assessment Tools in IPV Calls
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Dale Ballucci, Mary Ann Campbell, and Carmen Gill
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Power (social and political) ,Engineering ,business.industry ,05 social sciences ,050501 criminology ,Receptivity ,Risk management tools ,Public relations ,business ,Law ,0505 law - Published
- 2017
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106. The Girls Next Door: Bringing the Home Front to the Front Lines
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D'Ann Campbell
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History ,History and Philosophy of Science ,Home front ,business.industry ,Telecommunications ,business ,Front (military) - Published
- 2020
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107. Nitrogen fixation in nodulated legumes in relation to the assimilation of carbon
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Lawrie, Ann Campbell
- Subjects
583 - Abstract
There is a considerable volume of work which suggests that photosynthetic assimilates are important for nitrogen fixation and, in the work described in this thesis, attempts have been made to clarify the relationship between nitrogen fixation and photosynthetic assimilates in the nodules of two leguminous species - Pisum sativum L. and Vicia faba L. Simultaneous measurements of acetylene-reducing activity and radioactivity of C-labelled photosyhthates in the nodules have been made over a wide range of experimental conditions. In order to verify that the conditions used in the acetylene reduction assay were suitable for the species studied, the parameters thought most likely to affect acetylene-reducing activity in the nodules - those of temperature of incubation, oxygen and acetylene concentrations and the nature of the biological material assayed - were investigated. Optimum conditions were broadly similar for both species and differences between the species were probably due to differences in the biological materials themselves, such as nodule size and whether nodules were attached to or detached from the host plant. Nitrogenase activity changed during growth of both species and differences between the two species were thought to be due to different patterns of flowering and fruiting. Studies of pea plants during growth showed that nodules active in nitrogen fixation accumulated most C-labelled photosynthesis, but that a substantial proportion was not used in nitrogen fixation, but in respiration and growth of the nodule. Both nitrogenase activity and the accumulation of C-labelled photosynthates in nodules declined when flowering and fruiting took place and this was believed to be due partly to a redirection of the photosynthetic assimilates within the plant to the developing seed. However, removal of the shoot apex did not result consistently in increases in nitrogenase activity, even though the accumulation of photpsynthates increased, and so it is believed that, in this instance, control of nitrogenase activity is exerted by some factor other than, or additional to, the supply of photosynthates to the bacteroids. Light and photpperiod were shown to play important rules in the regulation of nitrogenase activity of pea nodules. Darkening pea plants resulted in large reductions in both nitrogenase activity and lAe ethanololuble carbohydrajfces in the nodules in 24 hours, but there was no corres- ponding reduction in the accumulation of C-labelled photosynthates manufactured just prior to darkening. However, the accumulation in ihe nodules of 14C-labelled photosynthates manufactured after darkened plants were returned to the light was much reduced and recovery of accumulation of photosynthates preceded recovery in nitrogenase activity. Although changes in the artificial light intensity to which pea plants were exposed for a short period had little effect on nitrogenase activity, diurnal fluctuations in nitrogenase activity were observed. However, maxima in nittogenase activity did not correspond with maxima in light intensity, but occurred in the evening due to the accumulation of photosynth ates translocated to the nodules after a delay of 4 to 8 hours. An additional mid-day maximum was observed sometimes and was believed to be due to changes in airibient temperature. In both species, a large proportion of the 14C-labelled photosynthates in the nodules were recovered as sugars, but there was some indication that ethanol-insoluble compounds were formed in pea nodules. Some photosynthates were rapidly utilised, as basic compounds were formed in bean nodules only 30 minutes after exposure of the shoots to CO2. Accumulation of basic compounds in detached bean nodules exposed to CO2 did not inhibit nitrogen fixation, and it is likely that organic acids formed by carboxylation reactions were aminated directly, as sugars were unlabelled. Microautoradiography indicated that the main site of accumulation of C-labelled photosynthates was the young infected cells near the meristematic tip of pea nodules, whereas histochemical tests with tetrazollum salts suggested that most nitrogen fixation took place in older cells. Thus the site of maximum accumulation of C-labelled photosynthates does not appcirently correspond with the site of maximum nitrogen fixation and therefore this observation supports the suggestion that a substantial proportion of the photosynthates which accumulate in the nodules are iiot used directly in nitrogen fixation. It is suggested that nitrogen fixation is not supported by reserve products, such as starch and poly-g-hydroxybutyric acid, in pea nodules, but by a supply of photosynthates which are only available when the requirements of the actively growing regions of the nodule have been met and which, after amination, are exported rapidly from nitrogen-fixing cells.
- Published
- 1973
108. Visualizing the lateral somitic frontier in the Prx1Cre transgenic mouse
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Durland, J. Logan, Sferlazzo, Matteo, Logan, Malcolm, and Burke, Ann Campbell
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- 2008
109. Making Love: Sentiment and Sexuality in Eighteenth-Century British Literature by Paul Kelleher
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Ann Campbell
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British literature ,Literature ,History ,business.industry ,Human sexuality ,business - Published
- 2018
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110. A Phase Model with Large Time Delayed Coupling
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Isam Al-Darabsah and Sue Ann Campbell
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Physics ,Coupling ,Mathematical analysis ,FOS: Physical sciences ,Statistical and Nonlinear Physics ,Delay differential equation ,Function (mathematics) ,Dynamical Systems (math.DS) ,Type (model theory) ,Condensed Matter Physics ,01 natural sciences ,Stability (probability) ,Synchronization ,Nonlinear Sciences - Adaptation and Self-Organizing Systems ,010305 fluids & plasmas ,Connection (mathematics) ,0103 physical sciences ,Phase model ,FOS: Mathematics ,Mathematics - Dynamical Systems ,010306 general physics ,Adaptation and Self-Organizing Systems (nlin.AO) - Abstract
We consider two identical oscillators with weak, time delayed coupling. We start with a general system of delay differential equations then reduce it to a phase model. With the assumption of large time delay, the resulting phase model has an explicit delay and phase shift in the argument of the phases and connection function, respectively. Using the phase model, we prove that for any type of oscillators and any coupling, the in-phase and anti-phase phase-locked solutions always exist and give conditions for their stability. We show that for small delay these solutions are unique, but with large enough delay multiple solutions of each type with different frequencies may occur. We give conditions for the existence and stability of other types of phase-locked solutions. We discuss the various bifurcations that can occur in the phase model as the time delay is varied. The results of the phase model analysis are applied to Morris–Lecar oscillators with diffusive coupling and compared with numerical studies of the full system of delay differential equations. We also consider the case of small time delay and compare the results with the existing ones in the literature.
- Published
- 2019
111. Women Who Kill
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Lori Ann Campbell and Vickie Jensen
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- 2019
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112. Spatially localized cluster solutions in inhibitory neural networks
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Hwayeon Ryu, Victoria Booth, Zeynep Teymuroglu, Sue Ann Campbell, Xueying Wang, and Jennifer Miller
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Statistics and Probability ,Models, Neurological ,Perturbation (astronomy) ,Action Potentials ,Inhibitory postsynaptic potential ,Cell assembly ,Stability (probability) ,General Biochemistry, Genetics and Molecular Biology ,Reduction (complexity) ,03 medical and health sciences ,0302 clinical medicine ,Cluster (physics) ,Phase model ,Humans ,Computer Simulation ,Neuron network ,030304 developmental biology ,Neurons ,Physics ,0303 health sciences ,Quantitative Biology::Neurons and Cognition ,General Immunology and Microbiology ,Artificial neural network ,Applied Mathematics ,General Medicine ,Stability conditions ,Coupling (computer programming) ,Modeling and Simulation ,Nerve Net ,General Agricultural and Biological Sciences ,Biological system ,030217 neurology & neurosurgery - Abstract
Neurons in the inhibitory network of the striatum display cell assembly firing patterns which recent results suggest may consist of spatially compact neural clusters. Previous computational modeling of striatal neural networks has indicated that non-monotonic, distance-dependent coupling may promote spatially localized cluster firing. Here, we identify conditions for the existence and stability of cluster firing solutions in which clusters consist of spatially adjacent neurons in inhibitory neural networks. We consider simple non-monotonic, distance-dependent connectivity schemes in weakly coupled 1-D networks where cells make strong connections with their kth nearest neighbors on each side. Using the phase model reduction of the network system, we prove the existence of cluster solutions where neurons that are spatially close together are also synchronized in the same cluster, and find stability conditions for these solutions. Our analysis predicts the long-term behavior for networks of neurons, and we confirm our results by numerical simulations of biophysical neuron network models. Additionally, we add weaker coupling between closer neighbors as a perturbation to our network connectivity. We analyze the existence and stability of cluster solutions of the perturbed network and validate our results with numerical simulations. Our results demonstrate that an inhibitory network with non-monotonic, distance-dependent connectivity can exhibit cluster solutions where adjacent cells fire together.
- Published
- 2021
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113. Virally mediated misexpression of Hoxc-6 in the cervical mesoderm results in spinal nerve truncations
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Burke, Ann Campbell and Tabin, Clifford J.
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Genetic regulation -- Research ,Mesoderm -- Research ,Nerves, Spinal -- Research ,Biological sciences - Abstract
Members of the Hox gene family appear to regulate anterior-posterior (A-P) regionalization in embryos. Genetic manipulation of numerous Hox genes in the developing trunk region of vertebrates results in changes in the morphology of individual vertebrae. We have used virally mediated, targeted misexpression to ectopically express the Hoxc-6 protein in chick embryos. Hoxc-6 has an anterior border of expression at the cervical-thoracic transition in tetrapods. Misexpression of this gene in the cervical mesoderm of chick embryos results in dramatic truncations of the ventral rami of cervical spinal nerves in the infected region. These data point to a role for Hoxc-6 in axon guidance, and suggest that in addition to regulating proliferative rates, Hox gene expression provides positional information utilized in producing domain-specific extracellular signals.
- Published
- 1996
114. Mean-field models for heterogeneous networks of two-dimensional integrate and fire neurons.
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Wilten Nicola and Sue Ann Campbell
- Published
- 2013
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115. 6 Hox Genes and the Global Patterning of the Somitic Mesoderm
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Burke, Ann Campbell, primary
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- 1999
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116. Explicit and implicit training methods for improving native English speakers’ comprehension of nonnative speech
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Jason Litzenberg, Maxi-Ann Campbell, Stephanie Lindemann, and Nicolas Close Subtirelu
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060201 languages & linguistics ,Linguistics and Language ,Computer science ,06 humanities and the arts ,Training methods ,01 natural sciences ,Language and Linguistics ,Linguistics ,Education ,Comprehension ,Native english ,Transcription (linguistics) ,Perceptual learning ,0602 languages and literature ,0103 physical sciences ,010301 acoustics ,Perceptual adaptation ,Sentence ,Multiple choice - Abstract
Research on communication difficulties between native and nonnative speakers (NNSs) has generally focused on NNSs. However, native speakers’ (NSs) level of familiarity with nonnative accents can also affect communication. This study investigates whether implicit training (exposure to Korean-accented English through sentence transcription) and explicit training (learning about linguistic differences with a focus on Korean-accented English) can improve NSs’ comprehension of Korean-accented English. Participants in both training conditions showed greater improvement than the control group on sentence transcription tasks but not on multiple choice questions that assessed comprehension of a brief lecture. The results replicate past findings showing the effectiveness of implicit training and provide novel evidence of the effectiveness of explicit training. This suggests that explicit training can be effective in improving NSs’ understanding of short utterances when the training ensures participants have learned the material.
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- 2016
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117. Nonsmooth Bifurcations of Mean Field Systems of Two-Dimensional Integrate and Fire Neurons
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Sue Ann Campbell and Wilten Nicola
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Equilibrium point ,Differential equation ,Mathematical analysis ,01 natural sciences ,Manifold ,010305 fluids & plasmas ,03 medical and health sciences ,0302 clinical medicine ,Bifurcation theory ,Mean field theory ,Modeling and Simulation ,0103 physical sciences ,Piecewise ,030217 neurology & neurosurgery ,Analysis ,Bifurcation ,Mathematics ,Variable (mathematics) - Abstract
Mean field systems have recently been derived that adequately predict the behaviors of large networks of coupled integrate-and-fire neurons [W. Nicola and S.A. Campbell, J. Comput. Neurosci., 35 (2013), pp. 87--108]. The mean field system for a network of neurons with spike frequency adaptation is typically a pair of differential equations for the mean adaptation and synaptic gating variable of the network. These differential equations are nonsmooth, and, in particular, are piecewise smooth continuous (PWSC). Here, we analyze the smooth and nonsmooth bifurcation structure of these equations and show that the system is organized around a pair of co-dimension-two bifurcations that involve, respectively, the collision between a Hopf equilibrium point and a switching manifold, and a saddle-node equilibrium point and a switching manifold. These two co-dimension-two bifurcations can coalesce into a co-dimension-three nonsmooth bifurcation. As the mean field system we study is a nongeneric piecewise smooth conti...
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- 2016
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118. An NPZ Model with State-Dependent Delay Due to Size-Structure in Juvenile Zooplankton
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Sue Ann Campbell, Matt Kloosterman, and Francis J. Poulin
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Conservation law ,Biomass (ecology) ,Partial differential equation ,Applied Mathematics ,010102 general mathematics ,Delay differential equation ,Type (model theory) ,01 natural sciences ,Stability (probability) ,Zooplankton ,010101 applied mathematics ,Control theory ,Quantitative Biology::Populations and Evolution ,Applied mathematics ,Uniqueness ,0101 mathematics ,Mathematics - Abstract
The study of planktonic ecosystems is important as they make up the bottom trophic levels of aquatic food webs. We study a closed nutrient-phytoplankton-zooplankton (NPZ) model that includes size structure in the juvenile zooplankton. The closed nature of the system allows the formulation of a conservation law of biomass that governs the system. The model consists of a system of a nonlinear ordinary differential equation coupled to a partial differential equation. We are able to transform this system into one of delay differential equations where the delay is of threshold type and is state dependent. The system of delay differential equations can be further transformed into one with fixed delay. Using the different forms of the model, we perform a qualitative analysis of the solutions, which includes studying existence and uniqueness, positivity and boundedness, local and global stability, and conditions for extinction. Key parameters that are explored are the total biomass in the system and the maturity level at which the juvenile zooplankton reach maturity. Numerical simulations are also performed to verify our analytical results.
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- 2016
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119. The Role of Gender in Mental Health Court Admission and Completion
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Peter J. McLeod, Andrea R. Ennis, Mary Ann Campbell, Margo C. Watt, and Nicole M. Adams-Quackenbush
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medicine.medical_specialty ,05 social sciences ,Gender studies ,medicine.disease ,Mental illness ,Mental health ,Personality disorders ,Criminalization ,Mood ,Mood disorders ,050501 criminology ,medicine ,Substance use ,Psychiatry ,Psychology ,Law ,Social Sciences (miscellaneous) ,Mental health court ,0505 law - Abstract
Mental Health Courts (MHCs) have emerged across North America in an effort to address the criminalization of persons with mental illness. Despite a growing body of literature examining MHCs, research on the role of gender in MHCs remains scarce. For this study, secondary data were analysed to examine whether gender differences in mental illness and crime affected the likelihood of MHC admission and completion in referrals to the Nova Scotia MHC (507 men, 243 women). Consistent with predictions, MHC admission and completion rates were similar between men and women. Higher rates of psychotic and substance use disorders were observed among men, whereas women had higher rates of mood and personality disorders. Although cases with psychotic and mood disorders were more likely to be admitted to the MHC, and those with substance use and personality disorders were less likely to be admitted, these differences did not vary by gender. Contrary to prediction, men had higher rates of violent index offences than women; however, this difference was only present for those who were not admitted to the MHC. Findings are discussed in terms of contributions to the literature surrounding the role of gender in MHCs, as well as notable implications for MHC practices and research.
- Published
- 2016
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120. The development and evolution of the turtle body plan: inferring intrinsic aspects of the evolutionary process from experimental embryology
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Burke, Ann Campbell
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Developmental biology -- Research ,Anatomy -- Research ,Embryology -- Research ,Shells -- Physiological aspects ,Ontogeny -- Case studies ,Turtles -- Physiological aspects ,Morphogenesis -- Research - Abstract
SYNOPSIS. The body plan of turtles is unique among tetrapods in the presence of the shell. The structure of the carapace involves a unique relationship between the axial and the appendicular skeletons. A common developmental mechanism, an epithelial-mesenchymal interaction, has been identified in the early stages of carapace development by means of basic histological and immunofluorescence techniques. By analogy to other structures initiated by epithelial-mesenchymal interactions, it is hypothesized that carapace development is dependent on this interaction in the body wall. Surgical perturbations were designed to test the causal connection between the epithelial-mesenchymal interaction in the body wall and the unusual placement of the ribs in turtles. By comparison to data available on body wall formation in avian embryos, these experiments also shed light on the segregation of somitic and lateral plate cell populations and the embryonic origin of the scapula in turtles. This study specifically addresses the ontogeny of a unique tetrapod body plan. The ontogenetic information can be used to make inferences about the phylogeny of this body plan and how it could have evolved from the more typical primitive tetrapod. On a more general level this study explores the potential role of common developmental mechanisms in the generation of evolutionary novelties, and the developmental incongruities between homologous skeletal elements in different groups of tetrapods.
- Published
- 1991
121. Identification of a genetic contribution to Meniere's disease
- Author
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Colleen Ann Campbell
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Genetics ,medicine.medical_specialty ,Candidate gene ,business.industry ,Locus (genetics) ,Disease ,Audiology ,medicine.disease ,Exon ,medicine ,Endolymphatic hydrops ,business ,Gene ,Meniere's disease ,Genetic association - Abstract
Meniere’s disease (MD) is a complex disorder of the inner ear characterized by the symptoms of hearing loss, tinnitus, and vertigo, with an incidence in Caucasians of one in 1000. The hallmark histopathologic feature of MD is endolymphatic hydrops. Symptoms of MD typically present in the fourth decade of life, and the vertigo attacks experienced by patients with MD can be debilitating. Treatments aimed at alleviating the symptoms of MD are ineffective in approximately 30% of patients. Several studies have attempted to identify genetic factors important in MD through the use of families segregating the disease, but causative genes have not been identified. Many of these studies have been unsuccessful due to the fact that families of sufficient size to generate meaningful linkage results are extremely rare. Attempts to identify a genetic component to MD through the use of candidate gene association studies have been underpowered or poorly designed and therefore also unsuccessful. We hypothesize Meniere’s disease is a complex disorder that is due to the interplay of genetic and environmental factors. We tested this hypothesis using linkage and association studies. Initially, we focused on candidate gene replication association studies (KCNE1, KCNE3, iNOS), as well as testing a novel candidate gene (AQP4). We were unable to replicate the previous associations and although we could not identify an association between MD and AQP4 we did discover rare variants of AQP4 in our MD patient population. These variants segregate with a ‘syndromic’ MD phenotype. We also performed a genome-wide linkage study on a large Chilean family segregating MD over three generations and identified a novel MD locus on 1q32.11q32.3. Targeted exon capture and pyrosequencing of the region identified two potential disease-causing variants in two genes of unknown function. We next screened a cohort of singleton patients with MD for variants in these same genes. Surprisingly, in both genes, we identified common and rare variants supporting a possible role for either gene
- Published
- 2018
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122. Chaos in homeostatically regulated neural systems
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Peter J. Hellyer, Wilten Nicola, Claudia Clopath, and Sue Ann Campbell
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DYNAMICS ,0103 Numerical And Computational Mathematics ,Nerve net ,MIXED-MODE OSCILLATIONS ,Chaotic ,Mathematics, Applied ,General Physics and Astronomy ,01 natural sciences ,Synchronization ,010305 fluids & plasmas ,0302 clinical medicine ,Homeostatic plasticity ,0102 Applied Mathematics ,PLASTICITY ,BIFURCATIONS ,NEURONS ,Mathematical Physics ,Artificial neural network ,Applied Mathematics ,Physics ,Brain ,NETWORKS ,CANARDS ,Physics, Mathematical ,medicine.anatomical_structure ,Physical Sciences ,Neurons and Cognition (q-bio.NC) ,Biological system ,q-bio.NC ,0299 Other Physical Sciences ,Fluids & Plasmas ,Models, Neurological ,SYNAPTIC HOMEOSTASIS ,Stability (probability) ,Article ,MECHANISMS ,03 medical and health sciences ,Biological Clocks ,0103 physical sciences ,medicine ,Science & Technology ,Quantitative Biology::Neurons and Cognition ,Statistical and Nonlinear Physics ,Brain Waves ,Nonlinear system ,Nonlinear Dynamics ,FOS: Biological sciences ,Quantitative Biology - Neurons and Cognition ,SPIKES ,Node (circuits) ,Nerve Net ,030217 neurology & neurosurgery ,Mathematics - Abstract
Low-dimensional yet rich dynamics often emerge in the brain. Examples include oscillations and chaotic dynamics during sleep, epilepsy, and voluntary movement. However, a general mechanism for the emergence of low dimensional dynamics remains elusive. Here, we consider Wilson-Cowan networks and demonstrate through numerical and analytical work that a type of homeostatic regulation of the network firing rates can paradoxically lead to a rich dynamical repertoire. The dynamics include mixed-mode oscillations, mixed-mode chaos, and chaotic synchronization. This is true for single recurrently coupled node, pairs of reciprocally coupled nodes without self-coupling, and networks coupled through experimentally determined weights derived from functional magnetic resonance imaging data. In all cases, the stability of the homeostatic set point is analytically determined or approximated. The dynamics at the network level are directly determined by the behavior of a single node system through synchronization in both oscillatory and non-oscillatory states. Our results demonstrate that rich dynamics can be preserved under homeostatic regulation or even be caused by homeostatic regulation., 25 pages, 5 figures
- Published
- 2018
123. Fatty acid elongase (FAE) systems: An investigation of genetic redundancy
- Author
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Alexis Ann Campbell
- Subjects
Genetics ,chemistry.chemical_classification ,Elongase ,Biochemistry ,chemistry ,Genetic redundancy ,Fatty acid ,Biology - Published
- 2018
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124. Punica granatum L. Leaf Extract Attenuates Lung Inflammation in Mice with Acute Lung Injury
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Lanna K. Silva, Ádylla Wilenna Alves Dourado, Elizabeth S. Fernandes, Patrícia Maria Wiziack Zago, Eduardo Martins de Sousa, Valério Monteiro-Neto, Aruanã Joaquim Matheus Costa Rodrigues Pinheiro, Cinara R A V Monteiro, Natilene Mesquita Brito, Marisa Cristina Aranha Batista, Joicy Cortez de Sá, Jaciara Sá Gonçalves, Lidio Gonçalves Lima-Neto, and Lee Ann Campbell
- Subjects
0301 basic medicine ,lcsh:Immunologic diseases. Allergy ,Article Subject ,medicine.medical_treatment ,Immunology ,Lung injury ,Pharmacology ,Nitric oxide ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,medicine ,Immunology and Allergy ,Dexamethasone ,Lung ,medicine.diagnostic_test ,business.industry ,General Medicine ,respiratory system ,respiratory tract diseases ,030104 developmental biology ,Cytokine ,Bronchoalveolar lavage ,medicine.anatomical_structure ,chemistry ,030220 oncology & carcinogenesis ,Tumor necrosis factor alpha ,Kaempferol ,business ,lcsh:RC581-607 ,Research Article ,medicine.drug - Abstract
The hydroalcoholic extract of Punica granatum (pomegranate) leaves was previously demonstrated to be anti-inflammatory in a rat model of lipopolysaccharide- (LPS-) induced acute peritonitis. Here, we investigated the anti-inflammatory effects of the ethyl acetate fraction obtained from the pomegranate leaf hydroalcoholic extract (EAFPg) on the LPS-induced acute lung injury (ALI) mouse model. Male Swiss mice received either EAFPg at different doses or dexamethasone (per os) prior to LPS intranasal instillation. Vehicle-treated mice were used as controls. Animals were culled at 4 h after LPS challenge, and the bronchoalveolar lavage fluid (BALF) and lung samples were collected for analysis. EAFPg and kaempferol effects on NO and cytokine production by LPS-stimulated RAW 264.7 macrophages were also investigated. Pretreatment with EAFPg (100–300 mg/kg) markedly reduced cell accumulation (specially neutrophils) and collagen deposition in the lungs of ALI mice. The same animals presented with reduced lung and BALF TNF-α and IL-1β expression in comparison with vehicle controls (p<0.05). Additionally, incubation with either EAFPg or kaempferol (100 μg/ml) reduced NO production and cytokine gene expression in cultured LPS-treated RAW 264.7 macrophages. Overall, these results demonstrate that the prophylactic treatment with EAFPg attenuates acute lung inflammation. We suggest this fraction may be useful in treating ALI.
- Published
- 2018
125. Juvenile Risk Assessment
- Author
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Julie L. Wershler, Mary Ann Campbell, and Fred Schmidt
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050103 clinical psychology ,Environmental health ,050901 criminology ,05 social sciences ,Juvenile ,0501 psychology and cognitive sciences ,0509 other social sciences ,Risk assessment ,Psychology - Published
- 2018
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126. Examining the limits of cellular adaptation bursting mechanisms in biologically-based excitatory networks of the hippocampus
- Author
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Wilten Nicola, Frances K. Skinner, Sue Ann Campbell, F. Njap, and Katie A. Ferguson
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Cellular adaptation ,Computer science ,Nerve net ,Cognitive Neuroscience ,Models, Neurological ,Population ,Action Potentials ,Hippocampus ,Context (language use) ,Cellular and Molecular Neuroscience ,Bursting ,medicine ,Animals ,Computer Simulation ,Theta Rhythm ,education ,CA1 Region, Hippocampal ,Computational model ,education.field_of_study ,Pyramidal Cells ,Mathematical Concepts ,Adaptation, Physiological ,Sensory Systems ,Rats ,medicine.anatomical_structure ,Excitatory postsynaptic potential ,Neural Networks, Computer ,Nerve Net ,Neuroscience - Abstract
Determining the biological details and mechanisms that are essential for the generation of population rhythms in the mammalian brain is a challenging problem. This problem cannot be addressed either by experimental or computational studies in isolation. Here we show that computational models that are carefully linked with experiment provide insight into this problem. Using the experimental context of a whole hippocampus preparation in vitro that spontaneously expresses theta frequency (3---12 Hz) population bursts in the CA1 region, we create excitatory network models to examine whether cellular adaptation bursting mechanisms could critically contribute to the generation of this rhythm. We use biologically-based cellular models of CA1 pyramidal cells and network sizes and connectivities that correspond to the experimental context. By expanding our mean field analyses to networks with heterogeneity and non all-to-all coupling, we allow closer correspondence with experiment, and use these analyses to greatly extend the range of parameter values that are explored. We find that our model excitatory networks can produce theta frequency population bursts in a robust fashion.Thus, even though our networks are limited by not including inhibition at present, our results indicate that cellular adaptation in pyramidal cells could be an important aspect for the occurrence of theta frequency population bursting in the hippocampus. These models serve as a starting framework for the inclusion of inhibitory cells and for the consideration of additional experimental features not captured in our present network models.
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- 2015
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127. Content Themes of Alcohol Advertising in U.S. Television-Latent Class Analysis
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Matthis Morgenstern, James D. Sargent, Marloes W. G. Braam, Franziska Schoeppe, Mike Stoolmiller, and Julie Ann Campbell
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Male ,Alcohol Drinking ,Alcoholic Beverages ,Medicine (miscellaneous) ,Poison control ,Advertising ,Toxicology ,United States ,Article ,Latent class model ,Entertainment ,Psychiatry and Mental health ,Party class ,Content analysis ,Alcohol advertising ,Injury prevention ,Humans ,Female ,Television ,Psychology ,Theme (narrative) - Abstract
BACKGROUND: There is little alcohol research that reports on the thematic contents of contemporary alcohol advertisements in U.S. television. Studies of alcohol ads from 2 decades ago did not identify "Partying" as a social theme. Aim of this study was to describe and classify alcohol advertisements aired in national television in terms of contents, airing times, and channel placements and to identify different marketing strategies of alcohol brands. METHODS: Content analysis of all ads from the top 20 U.S. beer and spirit brands aired between July 2009 and June 2011. These were 581 unique alcohol ads accounting for 272,828 (78%) national television airings. Ads were coded according to predefined definitions of 13 content areas. A latent class analysis (LCA) was conducted to define content cluster themes and determine alcoholic brands that were more likely to exploit these themes. RESULTS: About half of the advertisements (46%) were aired between 3 am and 8 pm, and the majority were placed either in Entertainment (40%) and Sports (38%) channels. Beer ads comprised 64% of the sample, with significant variation in airing times and channels between types of products and brands. LCA revealed 5 content classes that exploited the "Partying," "Quality," "Sports," "Manly," and "Relax" themes. The partying class, indicative of ad messages surrounding partying, love, and sex, was the dominant theme comprising 42% of all advertisements. Ads for alcopops, flavored spirits, and liqueur were more likely to belong to the party class, but there were also some beer brands (Corona, Heineken) where more than 67% of ads exploited this theme. CONCLUSIONS: This is the first analysis to identify a partying theme to contemporary alcohol advertising. Future analyses can now determine whether exposure to that or other themes predicts alcohol misuse among youth audiences. Language: en
- Published
- 2015
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128. Multidimensional evaluation of a mental health court: Adherence to the risk-need-responsivity model
- Author
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Mary Ann Campbell, W Alex C Macaulay, Donaldo D. Canales, Ran Wei, Julie L. Wershler, and Angela E. Totten
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Adult ,Male ,Mental Health Services ,Canada ,medicine.medical_specialty ,Referral ,Psychological intervention ,Risk Assessment ,Arts and Humanities (miscellaneous) ,Recurrence ,Mentally Ill Persons ,Intervention (counseling) ,medicine ,Humans ,Psychiatry ,General Psychology ,Mental health court ,Recidivism ,Mental Disorders ,Criminals ,Mental illness ,medicine.disease ,Mental health ,Psychiatry and Mental health ,Needs assessment ,Female ,Psychology ,Law ,Needs Assessment ,Follow-Up Studies ,Clinical psychology - Abstract
The current study examined the impact of a mental health court (MHC) on mental health recovery, criminogenic needs, and recidivism in a sample of 196 community-based offenders with mental illness. Using a pre-post design, mental health recovery and criminogenic needs were assessed at the time of MHC referral and discharge. File records were reviewed to score the Level of Service/Risk-Need-Responsivity instrument (Andrews, Bonta, & Wormith, 2008) to capture criminogenic needs, and a coding guide was used to extract mental health recovery information at each time point. Only mental health recovery data were available at 12 months post-MHC involvement. Recidivism (i.e., charges) was recorded from police records over an average follow-up period of 40.67 months post-MHC discharge. Case management adherence to the Risk-Need-Responsivity (RNR) model of offender case management was also examined. Small but significant improvements were found for criminogenic needs and some indicators of mental health recovery for MHC completers relative to participants who were prematurely discharged or referred but not admitted to the program. MHC completers had a similar rate of general recidivism (28.6%) to cases not admitted to MHC and managed by the traditional criminal justice system (32.6%). However, MHC case plans only moderately adhered to the RNR model. Implications of these results suggest that the RNR model may be an effective case management approach for MHCs to assist with decision-making regarding admission, supervision intensity, and intervention targets, and that interventions in MHC contexts should attend to both criminogenic and mental health needs.
- Published
- 2015
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129. Phase models and clustering in networks of oscillators with delayed, all-to-all coupling
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Sue Ann Campbell and Zhen Wang
- Subjects
Coupling ,Control and Systems Engineering ,Control theory ,Synchronization networks ,Phase (waves) ,Delay differential equation ,Cluster analysis ,Topology ,Stability (probability) ,Synchronization ,Multistability ,Mathematics - Abstract
We consider a general model for a network of all-to-all coupled oscillators with time delayed connections. We reduce the system of delay differential equations to a phase model where the time delay enters as a phase shift. By analyzing the phase model, we study the existence and stability of cluster solutions. These are solutions where the oscillators divide into groups; oscillators within a group are synchronized, while oscillators in different groups are phase-locked with a fixed phase difference. We show that the time delay can lead to the multistability between different cluster states. Analytical results are compared with numerical studies of the full system of delay differential equations.
- Published
- 2015
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- View/download PDF
130. More Than a Native Speaker, Third Edition : An Introduction to Teaching English Abroad
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Don Snow, Maxi-Ann Campbell, Don Snow, and Maxi-Ann Campbell
- Subjects
- English language--Study and teaching--Foreign countries, English language--Study and teaching--Foreign speakers
- Abstract
Accelerate your journey from novice to skilled teacher! In this newly updated third edition, learn step-by-step how to effectively teach English abroad. Gain valuable tips and resources for teaching in an unfamiliar educational system, working with students of varying ages and skill levels, and adapting to life in a different culture. Revised and updated with new research findings and suggestions for utilizing current technology and media tools, this text is also accompanied by a website that is packed with hundreds of activity ideas and links to additional teaching and learning resources.
- Published
- 2017
131. Attitudes towards non-native pronunciation
- Author
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Maxi-Ann Campbell and Stephanie Lindemann
- Subjects
Key terms ,First language ,media_common.quotation_subject ,Section (typography) ,Personality ,Affect (linguistics) ,Pronunciation ,Psychology ,Socioeconomic status ,Cognitive psychology ,media_common - Abstract
Listeners often feel comfortable making non-linguistic judgements about speakers, including drawing conclusions about their education, economic status and personality based on their pronunciation. This is particularly true of reactions to non-native speakers (NNSs), whose pronunciation is often measured against native speaker (NS) norms. However, there are also several other factors that affect listeners’ evaluations, such as where they believe, or are told, the speaker is from and what this person looks like. Educators, researchers and NNSs themselves may wish to take an understanding of such factors into account when deciding how to respond to negative evaluations of non-native pronunciation. The chapter’s first section introduces key terms and approaches used to investigate attitudes towards NNS pronunciation and the findings from studies that employed these methods. The chapter’s later sections consider other social factors that affect how people evaluate and react to NNSs. Finally, the chapter suggests future directions for teachers and researchers interested in addressing issues related to listeners’ attitudes towards non-native pronunciation.
- Published
- 2017
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132. More Than Peer Production
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David P. Randall, Kodlee Yin, Abigail Evans, Cecilia Aragon, Katie Davis, Julie Ann Campbell, and Sarah Evans
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Social and Information Networks (cs.SI) ,FOS: Computer and information sciences ,Discussion group ,Computer science ,media_common.quotation_subject ,05 social sciences ,Computer Science - Human-Computer Interaction ,Media studies ,050301 education ,Computer Science - Social and Information Networks ,Participant observation ,Informal learning ,Peer production ,Human-Computer Interaction (cs.HC) ,Computer Science - Computers and Society ,H.5.3 ,Reading (process) ,Computers and Society (cs.CY) ,0502 economics and business ,Ethnography ,Thematic analysis ,Affordance ,0503 education ,050203 business & management ,media_common - Abstract
From Harry Potter to American Horror Story, fanfiction is extremely popular among young people. Sites such as Fanfiction.net host millions of stories, with thousands more posted each day. Enthusiasts are sharing their writing and reading stories written by others. Exactly how does a generation known more for videogame expertise than long-form writing become so engaged in reading and writing in these communities? Via a nine-month ethnographic investigation of fanfiction communities that included participant observation, interviews, a thematic analysis of 4,500 reader reviews and an in-depth case study of a discussion group, we found that members of fanfiction communities spontaneously mentor each other in open forums, and that this mentoring builds upon previous interactions in a way that is distinct from traditional forms of mentoring and made possible by the affordances of networked publics. This work extends and develops the theory of distributed mentoring. Our findings illustrate how distributed mentoring supports fanfiction authors as they work to develop their writing skills. We believe distributed mentoring holds potential for supporting learning in a variety of formal and informal learning environments.
- Published
- 2017
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133. Outgrowing Neurological Diseases: Microcircuits, Conduction Delay and Childhood Absence Epilepsy
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John Milton, Jianhong Wu, Jacques Bélair, and Sue Ann Campbell
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0301 basic medicine ,Nervous system ,Time delays ,Recurrent excitation ,business.industry ,Axonal conduction ,medicine.disease ,03 medical and health sciences ,Epilepsy ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,Childhood absence epilepsy ,medicine ,business ,Conduction delay ,Neuroscience ,030217 neurology & neurosurgery ,Multistability - Abstract
The study of familial disorders characterized by recurring changes in neurodynamics, such as epileptic seizures, paralysis and headaches, provide opportunities to identify the mechanisms for dynamic changes in the nervous system. Many of these diseases are channelopathies. The computational challenge is to understand how a constantly present molecular defect in an ion channel can give rise to paroxysmal changes in neurodynamics. The most common of these channelopathies is childhood absence epilepsy (CAE). Here we review the dynamical properties of three neural microcircuits thought to be important in epilepsy: counter inhibition, recurrent inhibition and recurrent excitation. Time delays, \(\tau \), are an intrinsic property of these microcircuits since the time for a signal to travel between two neurons depends on the distance between them and the axonal conduction velocity. It is shown that all of these microcircuits can generate multistability provided that \(\tau \) is large enough. The term “multistability” means that there can be the co-existence of two or more attractors. Attention is drawn to the transient dynamics which can be associated with transitions between attractors, such as delay-induced transient oscillations. In this way we link the paroxysmal nature of seizure recurrences in CAE with time-delayed multistable dynamical systems. The tendency of children with CAE to outgrow their epilepsy is linked to developmental changes in axonal myelination which decrease \(\tau \).
- Published
- 2017
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134. Prediction of General and Violent Recidivism Among Mentally Disordered Adult Offenders
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Angela E. Totten, Ran Wei, Donaldo D. Canales, and Mary Ann Campbell
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Predictive validity ,medicine.medical_specialty ,Recidivism ,Level of service ,Large effect size ,Specific risk ,Pathology and Forensic Medicine ,Test (assessment) ,medicine ,Adult Offenders ,Psychology ,Risk assessment ,Psychiatry ,Law ,General Psychology ,Clinical psychology - Abstract
The present investigation examined the predictive validity of the Level of Service/Risk–Need–Responsivity (LS/RNR) instrument for general and violent recidivism in a sample of 138 community-supervised adult mentally disordered offenders. The General Risk/Need section was strongly predictive of general recidivism, whereas the Specific Risk/Need section most strongly predicted violent recidivism. Among males, the General Risk/Need section produced a large effect size for general recidivism, whereas general and violent outcomes for females were best predicted by the Specific Risk/Need section. Across diagnostic subgroups, the General and Specific Risk/Need sections predicted general but not violent recidivism; however, many subgroups were small, highlighting a need for replication research with larger samples. The Other Client Issues and Special Responsivity Considerations sections did not significantly inform recidivism prediction. Broadly interpreted, the overall pattern supports the LS/RNR instrument as valid for use with mentally disordered offenders.
- Published
- 2014
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135. Strictly Business: Marriage, Motherhood, and Surrogate Families as Entrepreneurial Ventures in Moll Flanders
- Author
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Ann Campbell
- Subjects
General Medicine ,Sociology - Published
- 2014
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136. A single-cell platform for reconstituting and characterizing fatty acid elongase component enzymes
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Trang T. T. Hoang, Alexis Ann Campbell, Basil J. Nikolau, M. Ann D. N. Perera, Kenna E. Stenback, and Kayla Flyckt
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0106 biological sciences ,0301 basic medicine ,Amino Acid Motifs ,Mutant ,Arabidopsis ,Yeast and Fungal Models ,medicine.disease_cause ,Biochemistry ,01 natural sciences ,Phylogeny ,Plant Proteins ,chemistry.chemical_classification ,Mutation ,Multidisciplinary ,biology ,Fatty Acids ,Eukaryota ,Gene Pool ,Plants ,Plants, Genetically Modified ,Lipids ,Enzymes ,Mutant Strains ,Experimental Organism Systems ,Seeds ,Medicine ,Research Article ,Genotype ,Fatty Acid Elongases ,Science ,Arabidopsis Thaliana ,Saccharomyces cerevisiae ,Mutagenesis (molecular biology technique) ,Brassica ,Research and Analysis Methods ,Zea mays ,Saccharomyces ,03 medical and health sciences ,Model Organisms ,Species Specificity ,Plant and Algal Models ,Genetics ,medicine ,Grasses ,Evolutionary Biology ,Population Biology ,Arabidopsis Proteins ,Genetic Complementation Test ,Organisms ,Fungi ,Computational Biology ,Biology and Life Sciences ,Proteins ,Fatty acid ,biology.organism_classification ,Yeast ,Maize ,030104 developmental biology ,Enzyme ,chemistry ,Mutagenesis, Site-Directed ,Animal Studies ,Enzymology ,Heterologous expression ,Population Genetics ,010606 plant biology & botany - Abstract
Fatty acids of more than 18-carbons, generally known as very long chain fatty acids (VLCFAs) are essential for eukaryotic cell viability, and uniquely in terrestrial plants they are the precursors of the cuticular lipids that form the organism's outer barrier to the environment. VLCFAs are synthesized by fatty acid elongase (FAE), which is an integral membrane enzyme system with multiple components. The genetic complexity of the FAE system, and its membrane association has hampered the biochemical characterization of FAE. In this study we computationally identified Zea mays genetic sequences that encode the enzymatic components of FAE and developed a heterologous expression system to evaluate their functionality. The ability of the maize components to genetically complement Saccharomyces cerevisiae lethal mutants confirmed the functionality of ZmKCS4, ZmELO1, ZmKCR1, ZmKCR2, ZmHCD and ZmECR, and the VLCFA profiles of the resulting strains were used to infer the ability of each enzyme component to determine the product profile of FAE. These characterizations indicate that the product profile of the FAE system is an attribute shared among the KCS, ELO, and KCR components of FAE.
- Published
- 2019
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- View/download PDF
137. Look and Do Ancient Greece. Teacher's Manual: Primary Program, Greek Art & Architecture [and] Workbook: The Art and Architecture of Ancient Greece [and] K-4 Videotape. History through Art and Architecture.
- Author
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Luce, Ann Campbell
- Abstract
This resource, containing a teacher's manual, reproducible student workbook, and a color teaching poster, is designed to accompany a 21-minute videotape program, but may be adapted for independent use. Part 1 of the program, "Greek Architecture," looks at elements of architectural construction as applied to Greek structures, and demonstrates Greek column styles. Part 2, "Greek Sculpture," discusses 3-dimensional design and stylized decoration. Several exemplars of Greek sculpture are shown. The Teacher's Manual includes a list of slides and gives strategies for using the video tape program in the classroom. The student workbook includes worksheets requiring written and/or drawn responses, an illustrated dictionary of Greek deities, and a student quiz. The poster depicts an illustrated time chart, maps of Greece and Alexander's Empire, 323 B.C., large diagrams of the Acropolis, the Parthenon ground plan, and column orders. (MM)
- Published
- 1987
138. Look and Do Ancient Egypt. Teacher's Manual: Primary Program, Ancient Egypt Art & Architecture [and] Workbook: The Art and Architecture of Ancient Egypt [and] K-4 Videotape. History through Art and Architecture.
- Author
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Luce, Ann Campbell
- Abstract
This resource contains a teaching manual, reproducible student workbook, and color teaching poster, which were designed to accompany a 2-part, 34-minute videotape, but may be adapted for independent use. Part 1 of the program, "The Old Kingdom," explains Egyptian beliefs concerning life after death as evidenced in art, architecture and the mummification process. Part 2, "The New Kingdom," presents the stories of Queen Hatshepsut, Pharaoh Tuthmoosis III, and Pharaoh Ramesses II as deciphered through art, architecture and hieroglyphics. The Teacher's Manual gives strategies for using the videotape and student workbook. A timeline of ancient Egypt and a list of filmstrip frames is provided. The student workbook includes worksheets requiring written and/or drawn responses, simplified explanations of the videotape program information, an illustrated iconography of Egyptian deities, and student quizzes. The poster presents a cross section of the Great Pyramid, diagrams of various Egyptian architectural sites, a map, timeline, and an illustrated iconography. (MM)
- Published
- 1988
139. Clandestine Marriage and Frances Burney’s Critique of Matrimony in Cecilia
- Author
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Ann Campbell
- Subjects
Cultural Studies ,History ,Dystopia ,Literature and Literary Theory ,Visual Arts and Performing Arts ,Parliament ,media_common.quotation_subject ,Gender studies ,Courtship ,Politics ,Scapegoat ,Memoir ,Narrative ,Sociology ,Duty ,media_common - Abstract
This essay argues that Frances Burney in Cecilia; or Memoirs of an Heiress (1782) critiques political debates and literary conventions focused on clandestine marriage. Through two plots of this novel, one economic and one focused on courtship, Burney interprets clandestine marriage as a scapegoat for the deeply flawed institution of marriage itself. The courtship narrative rewrites several aspects of conventional clandestine marriage plots, such as stock male characters, lengthy debates between love and duty, climactic wedding scenes, and punitive conclusions. The economic plot, featuring the stories of Mrs. Hill, Henrietta Belfield, and Priscilla Harrel, undermines Parliament’s claims about the economic outcomes of heiresses’ marital choices. The economic plot eventually usurps the courtship plot, leading to a dystopian conclusion that tacitly argues marriage itself is the problem, not deviations from an idealized norm of parentally approved companionate marriages of choice.
- Published
- 2013
- Full Text
- View/download PDF
140. The Bifurcation Study of 1:2 Resonance in a Delayed System of Two Coupled Neurons
- Author
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Guihong Fan, Sue Ann Campbell, Gail S. K. Wolkowicz, and Huaiping Zhu
- Subjects
Nonlinear Sciences::Chaotic Dynamics ,Period-doubling bifurcation ,Pitchfork bifurcation ,Bifurcation theory ,Transcritical bifurcation ,Mathematical analysis ,Homoclinic bifurcation ,Saddle-node bifurcation ,Bogdanov–Takens bifurcation ,Bifurcation diagram ,Nonlinear Sciences::Pattern Formation and Solitons ,Analysis ,Mathematics - Abstract
In this paper, we consider a delayed system of differential equations modeling two neurons: one is excitatory, the other is inhibitory. We study the stability and bifurcations of the trivial equilibrium. Using center manifold theory for delay differential equations, we develop the universal unfolding of the system when the trivial equilibrium point has a double zero eigenvalue. In particular, we show a universal unfolding may be obtained by perturbing any two of the parameters in the system. Our study shows that the dynamics on the center manifold are characterized by a planar system whose vector field has the property of 1:2 resonance, also frequently referred as the Bogdanov–Takens bifurcation with $$Z_2$$ symmetry. We show that the unfolding of the singularity exhibits Hopf bifurcation, pitchfork bifurcation, homoclinic bifurcation, and fold bifurcation of limit cycles. The symmetry gives rise to a “figure-eight” homoclinic orbit.
- Published
- 2013
- Full Text
- View/download PDF
141. Dismantling the Digital Dollhouse: Will Wright'sThe Simsand Virtual Consumption
- Author
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Rafael Miguel Montes and Andrea Ann Campbell
- Subjects
Wright ,Visual Arts and Performing Arts ,Communication ,media_common.quotation_subject ,Art ,Consumption (sociology) ,Postmodernism ,media_common ,Visual arts - Abstract
In his essay “Answering the Question: What is Postmodernism?,” Jean-Francois Lyotard offers a useful paradigm with which to elucidate the practice of consumption within an ever- expanding framework...
- Published
- 2013
- Full Text
- View/download PDF
142. Supporting Mothers’ Engagement in a Community-Based Methadone Treatment Program
- Author
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Jennifer Colpitts, Nicole Letourneau, Jennifer Woodland, and Mary Ann Campbell
- Subjects
lcsh:RT1-120 ,Community based ,medicine.medical_specialty ,Methadone maintenance ,Pediatrics ,lcsh:Nursing ,Article Subject ,business.industry ,Addiction ,media_common.quotation_subject ,Public health ,Alternative medicine ,Service provider ,High risk families ,Family medicine ,mental disorders ,medicine ,business ,General Nursing ,Research Article ,Methadone ,medicine.drug ,media_common - Abstract
Unmanaged maternal opioid addiction poses health and social risks to both mothers and children in their care. Methadone maintenance treatment (MMT) is a targeted public health service to which nurses and other allied health professionals may refer these high risk families for support. Mothers participating in MMT to manage their addiction and their service providers were interviewed to identify resources to maximize mothers’ engagement in treatment and enhance mothers’ parenting capacity. Twelve mothers and six service providers were recruited from an outpatient Atlantic Canadian methadone treatment program. Two major barriers to engagement in MMT were identified by both mothers and service providers including (1) the lack of available and consistent childcare while mothers attended outpatient programs and (2) challenges with transportation to the treatment facility. All participants noted the potential benefits of adding supportive resources for the children of mothers involved in MMT and for mothers to learn how to communicate more effectively with their children and rebuild damaged mother-child relationships. The public health benefits of integrating parent-child ancillary supports into MMT for mothers are discussed.
- Published
- 2013
- Full Text
- View/download PDF
143. Phase models and clustering in networks of oscillators with delayed coupling
- Author
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Sue Ann Campbell and Zhen Wang
- Subjects
Physics ,Coupling ,Artificial neural network ,Phase (waves) ,FOS: Physical sciences ,34C15 ,Statistical and Nonlinear Physics ,Dynamical Systems (math.DS) ,Delay differential equation ,Condensed Matter Physics ,Topology ,01 natural sciences ,Stability (probability) ,Nonlinear Sciences - Adaptation and Self-Organizing Systems ,010305 fluids & plasmas ,03 medical and health sciences ,0302 clinical medicine ,Numerical continuation ,0103 physical sciences ,FOS: Mathematics ,Mathematics - Dynamical Systems ,Cluster analysis ,Adaptation and Self-Organizing Systems (nlin.AO) ,Circulant matrix ,030217 neurology & neurosurgery - Abstract
We consider a general model for a network of oscillators with time delayed, circulant coupling. We use the theory of weakly coupled oscillators to reduce the system of delay differential equations to a phase model where the time delay enters as a phase shift. We use the phase model to study the existence and stability of cluster solutions. Cluster solutions are phase locked solutions where the oscillators separate into groups. Oscillators within a group are synchronized while those in different groups are phase-locked. We give model independent existence and stability results for symmetric cluster solutions. We show that the presence of the time delay can lead to the coexistence of multiple stable clustering solutions. We apply our analytical results to a network of Morris Lecar neurons and compare these results with numerical continuation and simulation studies.
- Published
- 2016
144. List of Contributors
- Author
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Jacob Al-Hashemi, Salomon Amar, Subash Babu, Edward B. Breitschwerdt, Jerry L. Brunson, Iwona Buskiewicz, Lee Ann Campbell, Han-Oh Chung, Vivian Vasconcelos Costa, Dermot Cox, Danielle da Gloria de Souza, Mahalia S. Desruisseaux, Kelly S. Doran, Tammy R. Dugas, DeLisa Fairweather, Alison E. Fox-Robichaud, Nisha J. Garg, Felicity N.E. Gavins, Mitzi C. Glover, Sally Huber, Mikhail V. Khoretonenko, Jung Hwan Kim, Dorsey L. Kordick, Fabiana S. Machado, Claudia Lucia Martins Silva, Mauro Martins Teixeira, Hema P. Narra, Thomas B. Nutman, Carlos Robello, Bram Rochwerg, Michael E. Rosenfeld, Abha Sahni, Sanjeev K. Sahni, Alexandra Schubert-Unkmeir, Karen Y. Stokes, Herbert B. Tanowitz, Traci L. Testerman, David H. Walker, Jian-jun Wen, and Bryan G. Yipp
- Published
- 2016
- Full Text
- View/download PDF
145. Stability in a scalar differential equation with multiple, distributed time delays
- Author
-
Sue Ann Campbell and Israel Ncube
- Subjects
Time delays ,Differential equation ,Applied Mathematics ,010102 general mathematics ,Scalar (mathematics) ,Mathematical analysis ,Model parameters ,Delay differential equation ,Dynamical Systems (math.DS) ,34K20 ,01 natural sciences ,010101 applied mathematics ,Trivial solution ,Distributed parameter system ,FOS: Mathematics ,Mathematics - Dynamical Systems ,0101 mathematics ,Analysis ,Mathematics - Abstract
We consider a linear scalar delay differential equation (DDE), consisting of two arbitrary distributed time delays. We formulate necessary conditions for stability of the trivial solution which are independent of the distributions. For the case of one discrete and one gamma distributed delay, we give an explicit description of the region of stability of the trivial solution and discuss how this depends on the model parameters.
- Published
- 2016
- Full Text
- View/download PDF
146. Vascular Responses to Chlamydia pneumoniae Infection
- Author
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Lee Ann Campbell and Michael E. Rosenfeld
- Subjects
Chlamydia ,Endothelium ,Vascular disease ,Inflammation ,Biology ,medicine.disease ,Chronic infection ,medicine.anatomical_structure ,In vivo ,Immunology ,medicine ,medicine.symptom ,Receptor ,Pathogen - Abstract
Chlamydia pneumoniae is an obligate intracellular pathogen that has been found in atherosclerotic lesions and chronic infection has been linked to an increased risk of cardiovascular disease. C. pneumoniae infects all of the cell types in normal and diseased blood vessels. In this chapter, we discuss the receptors that mediate the cellular uptake of C. pneumoniae and the unique intracellular developmental cycle of C. pneumoniae including conversion to a persistent phenotype. We further discuss the specific in vitro responses of vascular cells to C. pneumoniae infection with a focus on the role of toll-like receptors and induction of cytokine expression as well as effects on cellular metabolism and turnover. We also discuss the in vivo responses including the effects on vascular reactivity and atherosclerosis and include discussion of the results of clinical trials with antibiotics for reducing cardiovascular disease end points. We conclude the chapter by discussing how C. pneumoniae infection can have indirect systemic effects that could have an impact on the progression of vascular disease.
- Published
- 2016
- Full Text
- View/download PDF
147. Youth Psychopathic Traits and Their Impact on Long-Term Criminal Offending Trajectories
- Author
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Heather L. Dyck, Julie L. Wershler, Mary Ann Campbell, and Fred Schmidt
- Subjects
medicine.medical_specialty ,Psychopathy Checklist ,Health (social science) ,Psychopathy ,Poison control ,Human factors and ergonomics ,medicine.disease ,Suicide prevention ,Occupational safety and health ,Injury prevention ,Developmental and Educational Psychology ,Trait ,medicine ,Psychology ,Psychiatry ,Law ,Clinical psychology - Abstract
The current study examined long-term offending patterns in relation to youth psychopathic traits. Criminal records of 126 adolescent offenders (80 male; 46 female) were analyzed for criminal activity between the ages of 12 and 23. Total scores on the Psychopathy Checklist: Youth Version were positively correlated with a higher number of overall offending incidents. After classifying youths into low ( n = 62), moderate ( n = 26), and high ( n = 38) psychopathic trait groups, results indicated that the moderate- and high-trait groups had consistently higher mean rates of criminal events (i.e., violent, nonviolent, drug related, and technical violations) throughout the follow-up period than the low-trait group. Contrary to what has been argued in previous psychopathy literature, a decrease in offending over time was observed in all three psychopathic trait groups. These results suggest that youths with psychopathic traits tend to display a higher level of criminal activity during adolescence, but are similar to lower psychopathic groups in also showing at least an initial decline in this behavior as they approach early adulthood.
- Published
- 2012
- Full Text
- View/download PDF
148. Institutional Offense Patterns in Adolescent Offenders
- Author
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Darcy A. Santor, Mary Ann Campbell, and Ainslie McDougall
- Subjects
medicine.medical_specialty ,Health (social science) ,Psychological intervention ,Poison control ,Suicide prevention ,Mental health ,Occupational safety and health ,Misconduct ,Injury prevention ,Developmental and Educational Psychology ,medicine ,Juvenile delinquency ,Psychiatry ,Psychology ,Law ,Clinical psychology - Abstract
The current study compared the antisocial and mental health functioning of incarcerated adolescents with histories of serious and persistent institutional misconduct to those with histories of minor forms of institutional misconduct. Institutional offense histories of 192 incarcerated adolescent offenders (84.5% male) were reviewed and their mental health was assessed using the Youth Self-Report (YSR) to determine whether mental health factors were more prevalent in serious/persistent institutional offenders. Youths with a history of serious/prolific institutional offending were younger at first arrest, had more convictions, spent more time incarcerated, and scored higher on YSR aggression and delinquency subscales than those with low/moderate institutional offending. Although antisociality is likely a major contributor to serious and persistent forms of institutional misconduct, these youths, especially the females, had significantly higher YSR anxiety/depression symptoms than the low/moderate institutional offending group. Although traditional criminogenic factors may be more salient to the risk of institutional misconduct, mental health should remain an important area of case management given its comorbidity with higher levels of misconduct and its potential impact on youths' responsivity to interventions focusing on criminogenic needs.
- Published
- 2012
- Full Text
- View/download PDF
149. An Analysis of General Public and Professional's Attitudes about Mental Health Courts: Predictors of a Positive Perspective
- Author
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Donaldo D. Canales, Angela Burbridge, Teresa Smith, Mary Ann Campbell, Naomi L. Doucette, and Ainslie McDougall
- Subjects
Psychiatry and Mental health ,Government ,medicine.medical_specialty ,Perspective (graphical) ,medicine ,Sample (statistics) ,Pshychiatric Mental Health ,Psychology ,Psychiatry ,Mental health ,health care economics and organizations ,Mental health court ,Pathology and Forensic Medicine - Abstract
Little research has been conducted on the public perception of mental health courts (MHCs) despite its potential to influence government support and funding. To measure public and professionals’ opinions about MHCs, self-report attitude measures were administered online to members of the general public (n = 272) and professional groups with previous employment-related exposure to persons with mental health issues (n = 237). Over 86% of the professional exposure sample had positive attitudes towards MHCs, whereas only 4% reported negative opinions. Approximately 70% of professionals supported government funding for a MHC in their community and 57% agreed even if this led to a tax increase. The public sample was also generally positive in their opinions, and only 3% reported negative opinions. Approximately 80% of public sample reported that they would support or strongly support government funding for a MHC in their community, and 58% would support it even if it led to a tax increase. Positive attitudes we...
- Published
- 2012
- Full Text
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150. Phase models and oscillators with time delayed coupling
- Author
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Sue Ann Campbell and Ilya Kobelevskiy
- Subjects
Physics ,Coupling ,Time delayed ,Applied Mathematics ,Mathematical analysis ,Phase model ,Phase (waves) ,Discrete Mathematics and Combinatorics ,Delay differential equation ,Stability (probability) ,Analysis ,Synchronization ,Bifurcation - Abstract
We consider two identical oscillators with time delayed coupling, modelled by a system of delay differential equations. We reduce the system of delay differential equations to a phase model where the time delay enters as a phase shift. By analyzing the phase model, we show how the time delay affects the stability of phase-locked periodic solutions and causes stability switching of in-phase and anti-phase solutions as the delay is increased. In particular, we show how the phase model can predict when the phase-flip bifurcation will occur in the original delay differential equation model. The results of the phase model analysis are applied to pairs of Morris-Lecar oscillators with diffusive or synaptic coupling and compared with numerical studies of the full system of delay differential equations.
- Published
- 2012
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