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101. Role of poly-ADP-ribose polymerase inhibitors after brain progression in platinum-sensitive ovarian cancer: a case report and review of the literature

Author: Gonzalo Lendinez-Sanchez, Tamara Diaz-Redondo, Marcos Iglesias-Campos, Lucía Garrido-Almazán, Emilio Alba-Conejo, Antonio Rueda-Dominguez, and Alfonso Sanchez-Muñoz
Subjects: PARPi, olaparib, ovarian cancer, brain metastases, BRCA, case report, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: IntroductionThe incidence of brain metastases in ovarian cancer is quite rare, being approximately 1%–2%. According to retrospective studies, patients with BRCA 1/2 mutations present a higher risk. The trimodal approach based on surgery, radiotherapy, and chemotherapy presents better outcomes, but the prognosis remains poor with overall survival since the brain progression is around 1 year. Poly-ADP-ribose polymerase inhibitors (PARPi) have provided a new alternative for the management of advanced ovarian cancer. The SOLO2, NOVA, and ARIEL3 clinical trials do not refer data on patients with brain metastases, and the published evidence for PARPi in this setting comes only from case reports and retrospective studies.Case reportWe present the case of a 54-year-old woman with stage IV ovarian high-grade serous papillary carcinoma who, after 37 months of treatment with olaparib, presented a single brain lesion. After radical treatment with surgery and adjuvant whole-brain radiotherapy, she resumed olaparib with no evidence of disease during 15 months. After a second single brain relapse treated with stereotactic radiosurgery, the patient continued olaparib beyond the brain progression with no evidence of extracranial disease. Despite that there were no changes in size or number of brain lesions, the neurological situation progressively worsened and the patient died 8 months after the second progression.DiscussionThe higher incidence of brain metastases of ovarian cancer points out a possible tropism for the CNS in BRCA-mutated patients. In preclinical studies, PARPi has shown to cross the blood–brain barrier, with possible antitumor activity in the central nervous system (CNS) while maintaining control of extracranial disease. The best survival data are obtained with a trimodal approach, and adding a PARPi could improve the survival outcomes in the context of platinum-sensitivity disease. Targeted therapies combined with local treatments are also used in other malignancies, suggesting potential effectiveness due to tumor heterogeneity. PARPi before brain metastasis may delay its diagnosis, and using iPARP after brain metastases could improve the outcome of this population.ConclusionThe role that PARPi may have in the treatment of brain metastases of ovarian cancer requires more studies. In the context of radical treatment of brain metastasis (surgery and/or RT), with no evidence of extracranial disease, maintaining treatment with PARPi beyond the brain progression should be considered.
Published: 2024
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102. Comparison of parasitological methods for the identification of soil-transmitted helminths, including Strongyloides stercoralis, in a regional reference laboratory in northwestern Argentina: An observational study

Author: Elvia Nieves, Pedro Fleitas, Marisa Juárez, Cristina Almazán, Gabriela Flores, Jimena Alani, Ramón Diaz, Jorge Martos, Pamela Cajal, Rubén Cimino, and Alejandro Krolewiecki
Subjects: Soil-transmitted helminths, Neglected tropical disease, Methods, Strongyloides stercoralis, Composite reference standard, Infectious and parasitic diseases, RC109-216
Abstract: Soil-transmitted helminths (STH) are a significant public health problem in impoverished communities of tropical and subtropical areas. Improved diagnostic methods are crucial for Neglected Tropical Diseases programs, particularly for S. stercoralis, as traditional methods are inadequate. Thus, it is important to identify the most accurate and efficient methods for the diagnosis of STH. We performed a retrospective study analyzing laboratory data at the Instituto de Investigaciones de Enfermedades Tropicales from 2010 to 2019. The study included data from outpatients referred for stool analysis and public health interventions from urban and rural communities in northern Salta province, Argentina. Samples were included in this analysis if processed through sedimentation/concentration, Baermann, Harada-Mori and McMaster's, with a subgroup that also included Agar plate culture method (APC). Sensitivity was calculated against a composite reference standard. Of the 5625 samples collected, 944 qualified for this analysis, with a prevalence of 11.14% for A. lumbricoides, 8.16% for hookworm, 1.38% for T. trichiura, and 6.36% for S. stercoralis. The sedimentation/concentration method was the most sensitive for A. lumbricoides (96%), compared to the McMaster method, with a sensitivity of 62%. Similarly, for hookworms, sedimentation/concentration was more sensitive than McMaster's, Harada-Mori, and Baermann with sensitivities of 87%, 70%, 43%, and 13%, respectively. Most of these infections were of light intensity. For S. stercoralis, Baermann and sedimentation/concentration methods were the most sensitive, with 70% and 62% respectively, while Harada-Mori was the least sensitive. In a subset of 389 samples also analyzed by the APC, Baermann was more sensitive than APC for detecting S. stercoralis, and both methods were superior to Harada-Mori. Parasitological methods, mostly when used combined, offer adequate opportunities for the diagnosis of STH in clinical and public health laboratories. The incorporation of S. stercoralis into the control strategies of the World Health Organization requires rethinking the current diagnostic approach used for surveys. With sedimentation/concentration and Baermann appearing as the most sensitive methods for this species. Further studies, including implementation assessments, should help in identifying the most adequate and feasible all-STH diagnostic approach.
Published: 2024
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103. Prototipo de dispensador automático para la optimización de ventas en diferentes sectores

Author: Benjamin Vázquez Martínez, Jonathan Alejandro Estrada Garibay, David Jehosafath Castillo González, and David Ernesto Ochoa Almazán
Subjects: Automatización, Dosificación, Expendedora, Prototipo, Ventas, Engineering (General). Civil engineering (General), TA1-2040, Technology (General), T1-995
Abstract: El propósito de este trabajo es crear un prototipo de un sistema automatizado para el despacho de diversos productos, como semillas, cereales, clavos, tornillos, entre otros, con el objetivo de beneficiar tanto al consumidor como al proveedor. Se empleará una máquina dispensadora que utilizará la automatización y la dosificación para proporcionar un servicio eficiente. Además, se busca reducir el contacto directo entre el cliente y el vendedor, especialmente en el contexto de la pandemia de COVID-19, donde se ha identificado el intercambio de moneda como un medio de contagio [1]. Es importante destacar que el enfoque metodológico más adecuado para este proyecto es el cuantitativo, ya que se centra en la recolección de datos esenciales para un análisis y desarrollo más efectivos. Asimismo, el dispensador no se limitará a un solo tipo de producto, sino que será versátil y adaptable para su uso en diferentes industrias, permitiendo su funcionamiento las 24 horas del día. Para el desarrollo de este prototipo, los materiales propuestos son el MDF y acrílico, aunado a la impresión en 3D y el uso del software SolidWorks, la plataforma Wokwi para la simulación del sistema y los componentes que lo conforman, el hardware y los softwares que permitirán el funcionamiento de la dosificación, selección de producto y el cobro. Además, se utilizará el IDE Arduino para la programación y el código en el microcontrolador ESP32, lo que coadyuva a que el prototipo sea beneficioso en cuanto a la relación costo-calidad, posicionándolo como una opción viable respecto a su categoría: las máquinas de vending.
Published: 2024
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104. Yoga as a therapeutic approach to mental health in university students: a randomized controlled trial

Author: Yolanda Castellote-Caballero, María del Carmen Carcelén-Fraile, Agustín Aibar-Almazán, Yulieth Rivas-Campo, and Ana María González-Martín
Subjects: yoga, perceived stress, emotional wellbeing, anxiety, university students, Public aspects of medicine, RA1-1270
Abstract: ObjectivesThe purpose of this study has been to analyze the efficacy of a yoga-based intervention on stress, emotional wellbeing, state anxiety and trait anxiety in university students.MethodsThis study was a randomized controlled trial. The sample consisted of 129 university students, of which 65 underwent a yoga training for 12 weeks and a control group that did not carry out any type of intervention. The primary outcome was stress, which was collected through The Perceived Stress Scale (PSS). The secondary outcomes were emotional wellbeing which was measured through the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS), and anxiety through State–Trait Anxiety Inventory (STAI). All variables were measured before and after the intervention.ResultsParticipants in the experimental group showed statistically significant improvements in the primary outcome perceived stress (Cohen’s d = 0.44) and the secondary outcomes emotional wellbeing (Cohen’s d = 0.47), and both state anxiety (Cohen’s d = 0.38) and trait anxiety (Cohen’s d = 0.80) compared to the control group that did not carry out any type of physical training.ConclusionThis study demonstrated that a 12-week yoga intervention can significantly reduce perceived stress and anxiety, and improve emotional wellbeing in university students. Initially, the experimental group (EG) reported higher levels of stress and anxiety than the control group (CG), but after the intervention, the EG experienced significant improvements compared to the CG.
Published: 2024
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105. Reverse Genetics of Zika Virus Using a Bacterial Artificial Chromosome

Author: Nogales, Aitor, primary, Martínez-Sobrido, Luis, additional, and Almazán, Fernando, additional
Published: 2023
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106. Bacterial Artificial Chromosome Reverse Genetics Approaches for SARS-CoV-2

Author: Chiem, Kevin, primary, Nogales, Aitor, additional, Almazán, Fernando, additional, Ye, Chengjin, additional, and Martínez-Sobrido, Luis, additional
Published: 2023
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107. High-structure and its impact on performance gaps in large-enrollment frosh courses

Author: Morales-Almazan, Pedro, Pan, Hanjue, and Tom, Jasmine
Subjects: Mathematics - History and Overview
Abstract: We introduce the concept of structure-regions and their impact on student experience in large-enrollment frosh courses. These regions involve three major components: active learning, low-stakes assignments, and formative assessment. We analyze performance data and show that high-structure courses have a positive impact on class performance by decreasing the performance gap throughout the duration of a course., Comment: 12 pages, 2 figures, 1 table
Published: 2021

108. Measurement of the ${}^{136}$Xe two-neutrino double beta decay half-life via direct background subtraction in NEXT

Author: NEXT Collaboration, Novella, P., Sorel, M., Usón, A., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Bounasser, S., Byrnes, N., Cárcel, S., Carrión, J. V., Cebrián, S., Church, E., Conde, C. A. N., Contreras, T., Cossío, F. P., Denisenko, A. A., Díaz, G., Díaz, J., Dickel, T., Escada, J., Esteve, R., Fahs, A., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F. W., Freitas, E. D. C., Freixa, Z., Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., González-Díaz, D., Guenette, R., Gutiérrez, R. M., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero-Gómez, P., Herrero, V., Ho, J., Ifergan, Y., Jones, B. J. P., Kekic, M., Labarga, L., Laing, A., Larizgoitia, L., Lebrun, P., Gutierrez, D. Lopez, López-March, N., Losada, M., Mano, R. D. P., Martín-Albo, J., Martínez, A., Martínez-Lema, G., Martínez-Vara, M., McDonald, A. D., Meziani, Z. E., Mistry, K., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Vidal, J. Muñoz, Navarro, K., Nygren, D. R., Oblak, E., Odriozola-Gimeno, M., Palmeiro, B., Para, A., Pérez, J., Querol, M., Raymond, A., Redwine, A. B., Renner, J., Ripoll, L., Rivilla, I., García, Y. Rodríguez, Rodríguez, J., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Simón, A., Stanford, C., Teixeira, J. M. R., Thapa, P., Toledo, J. F., Torrent, J., Veloso, J. F. C. A., Vuong, T. T., Webb, R., White, J. T., Woodruff, K., and Yahlali, N.
Subjects: Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: We report a measurement of the half-life of the ${}^{136}$Xe two-neutrino double beta decay performed with a novel direct background subtraction technique. The analysis relies on the data collected with the NEXT-White detector operated with ${}^{136}$Xe-enriched and ${}^{136}$Xe-depleted xenon, as well as on the topology of double-electron tracks. With a fiducial mass of only 3.5 kg of Xe, a half-life of $2.34^{+0.80}_{-0.46}\textrm{(stat)}^{+0.30}_{-0.17}\textrm{(sys)}\times10^{21}~\textrm{yr}$ is derived from the background-subtracted energy spectrum. The presented technique demonstrates the feasibility of unique background-model-independent neutrinoless double beta decay searches., Comment: 9 pages, 7 figures, and 1 appendix
Published: 2021
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109. Searching for Hidden Neutrons with a Reactor Neutrino Experiment: Constraints from the STEREO Experiment

Author: Almazán, H., Bernard, L., Blanchet, A., Bonhomme, A., Buck, C., Sanchez, P. del Amo, Atmani, I. El, Labit, L., Lamblin, J., Letourneau, A., Lhuillier, D., Licciardi, M., Lindner, M., Materna, T., Méplan, O., Pessard, H., Pignol, G., Réal, J. -S., Ricol, J. -S., Roca, C., Rogly, R., Salagnac, T., Sarrazin, M., Savu, V., Schoppmann, S., Soldner, T., Stutz, A., and Vialat, M.
Subjects: High Energy Physics - Experiment, Nuclear Experiment
Abstract: Different extensions of the standard model of particle physics, such as braneworld or mirror matter models, predict the existence of a neutron sterile state, possibly as a dark matter candidate. This Letter reports a new experimental constraint on the probability $p$ for neutron conversion into a hidden neutron, set by the STEREO experiment at the high flux reactor of the Institut Laue-Langevin. The limit is $p<3.1\times 10^{-11}$ at $95 \%$ C.L. improving the previous limit by a factor 13. This result demonstrates that short-baseline neutrino experiments can be used as competitive passing-through-walls neutron experiments to search for hidden neutrons., Comment: 5 pages, 3 figures
Published: 2021
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110. Observations with KIDs Interferometer Spectrum Survey(KISS)

Author: Fasano, A., Catalano, A., Macías-Pérez, J. F., Aguiar, M., Beelen, A., Benoit, A., Bideaud, A., Bounmy, J., Bourrion, O., Bres, G., Calvo, M., Castro-Almazán, J. A., de Bernardis, P., De Petris, M., de Taoro, A. P., Fernández-Torreiro, M., Garde, G., Génova-Santos, R., Gomez, A., Gómez-Renasco, M. F., Goupy, J., Hoarau, C., Hoyland, R., Lagache, G., Marpaud, J., Marton, M., Monfardini, A., Peel, M. W., Pisano, G., Ponthieu, N., Rebolo, R., Roudier, S., Rubiño-Martín, J. A., Tourres, D., Tucker, C., and Vescovi, C.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: We describe the preliminary on-sky results of the KIDs Interferometer Spectrum Survey (KISS), a spectral imager with a 1 deg field of view (FoV). The instrument operates in the range 120-180 GHz from the 2.25 m Q-U-I JOint TEnerife telescope in Teide Observatory (Tenerife, Canary Islands), at 2 395 m altitude above sea level. Spectra at low resolution, up to 1.45 GHz, are obtained using a fast (3.72 Hz mechanical frequency) Fourier transform spectrometer, coupled to a continuous dilution cryostat with a stabilized temperature of 170 mK that hosts two 316-pixel arrays of lumped-element kinetic inductance detectors. KISS generates more than 3 000 spectra per second during observations and represents a pathfinder to demonstrate the potential for spectral mapping with large FoV. We give an overall description of the spectral mapping paradigm and we present recent results from observations, in this paper., Comment: 6 pages, 3 figures, to appear in the Proceedings of the International Conference entitled "mm Universe @ NIKA2", Rome (Italy), June 2021, EPJ Web of conferences
Published: 2021
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111. 2D Grid Map Generation for Deep-Learning-based Navigation Approaches

Author: Flores-Aquino, Gabriel O., Ortega, Jheison Duvier Díaz, Arvizu, Ricardo Yahir Almazan, Muñoz, Raúl López, Gutierrez-Frias, O. Octavio, and Vasquez-Gomez, J. Irving
Subjects: Computer Science - Robotics
Abstract: In the last decade, autonomous navigation for roboticshas been leveraged by deep learning and other approachesbased on machine learning. These approaches have demon-strated significant advantages in robotics performance. Butthey have the disadvantage that they require a lot of data toinfer knowledge. In this paper, we present an algorithm forbuilding 2D maps with attributes that make them useful fortraining and testing machine-learning-based approaches.The maps are based on dungeons environments where sev-eral random rooms are built and then those rooms are con-nected. In addition, we provide a dataset with 10,000 mapsproduced by the proposed algorithm and a description withextensive information for algorithm evaluation. Such infor-mation includes validation of path existence, the best path,distances, among other attributes. We believe that thesemaps and their related information can be very useful forrobotics enthusiasts and researchers who want to test deeplearning approaches. The dataset is available athttps://github.com/gbriel21/map2D_dataSet.git, Comment: 6 pages, 4 figures, conference, dataset
Published: 2021

112. TLDR: Twin Learning for Dimensionality Reduction

Author: Kalantidis, Yannis, Lassance, Carlos, Almazan, Jon, and Larlus, Diane
Subjects: Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence, Computer Science - Machine Learning
Abstract: Dimensionality reduction methods are unsupervised approaches which learn low-dimensional spaces where some properties of the initial space, typically the notion of "neighborhood", are preserved. Such methods usually require propagation on large k-NN graphs or complicated optimization solvers. On the other hand, self-supervised learning approaches, typically used to learn representations from scratch, rely on simple and more scalable frameworks for learning. In this paper, we propose TLDR, a dimensionality reduction method for generic input spaces that is porting the recent self-supervised learning framework of Zbontar et al. (2021) to the specific task of dimensionality reduction, over arbitrary representations. We propose to use nearest neighbors to build pairs from a training set and a redundancy reduction loss to learn an encoder that produces representations invariant across such pairs. TLDR is a method that is simple, easy to train, and of broad applicability; it consists of an offline nearest neighbor computation step that can be highly approximated, and a straightforward learning process. Aiming for scalability, we focus on improving linear dimensionality reduction, and show consistent gains on image and document retrieval tasks, e.g. gaining +4% mAP over PCA on ROxford for GeM- AP, improving the performance of DINO on ImageNet or retaining it with a 10x compression., Comment: Accepted at Transactions on Machine Learning Research (TMLR). Code available at: https://github.com/naver/tldr
Published: 2021

113. The Dynamics of Ions on Phased Radio-frequency Carpets in High Pressure Gases and Application for Barium Tagging in Xenon Gas Time Projection Chambers

Author: NEXT Collaboration, Jones, B. J. P., Raymond, A., Woodruff, K., Byrnes, N., Denisenko, A. A., Foss, F. W., Navarro, K., Nygren, D. R., Vuong, T. T., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Bounasser, S., Cárcel, S., Carrión, J. V., Cebrián, S., Church, E., Conde, C. A. N., Contreras, T., Cossío, F. P., Díaz, G., Díaz, J., Dickel, T., Escada, J., Esteve, R., Fahs, A., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Freitas, E. D. C., Freixa, Z, Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., González-Díaz, D., Guenette, R., Gutiérrez, R. M., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Hernando~Morata, J. A., Herrero-Gómez, P., Herrero, V., Ho, J., Ifergan, Y., Kekic, M., Labarga, L., Laing, A., Lebrun, P., Gutierrez, D. Lopez, López-March, N., Losada, M., Mano, R. D. P., Martín-Albo, J., Martínez, A., Martínez-Lema, G., Martínez-Vara, M., McDonald, A. D., Meziani, Z. E., Mistry, K., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Vidal, J. Muñoz, Novella, P., Oblak, E., Odriozola-Gimeno, M., Palmeiro, B., Para, A., Pérez, J., Querol, M., Redwine, A. B., Renner, J., Ripoll, L., Rivilla, I., García, Y. Rodríguez, Rodríguez, J., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Simón, A., Sorel, M., Stanford, C., Teixeira, J. M. R., Thapa, P., Toledo, J. F., Torrent, J., Usón, A., Veloso, J. F. C. A., Webb, R., Weiss-Babai, R., White, J. T., and Yahlali, N.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: Radio-frequency (RF) carpets with ultra-fine pitches are examined for ion transport in gases at atmospheric pressures and above. We develop new analytic and computational methods for modeling RF ion transport at densities where dynamics are strongly influenced by buffer gas collisions. An analytic description of levitating and sweeping forces from phased arrays is obtained, then thermodynamic and kinetic principles are used to calculate ion loss rates in the presence of collisions. This methodology is validated against detailed microscopic SIMION simulations. We then explore a parameter space of special interest for neutrinoless double beta decay experiments: transport of barium ions in xenon at pressures from 1 to 10 bar. Our computations account for molecular ion formation and pressure dependent mobility as well as finite temperature effects. We discuss the challenges associated with achieving suitable operating conditions, which lie beyond the capabilities of existing devices, using presently available or near-future manufacturing techniques., Comment: 26 pages, 16 figures v2: author list update and pre-journal submission adjustments
Published: 2021

114. Accurate sky signal reconstruction for ground-based spectroscopy with kinetic inductance detectors

Author: Fasano., A., Macías-Pérez, J. F., Benoit, A., Aguiar, M., Beelen, A., Bideaud, A., Bounmy, J., Bourrion, O., Bres, G., Calvo, M., Castro-Almazán, J. A., Catalano, A., de Bernardis, P., De Petris, M., de Taoro, A. P., Fernández-Torreiro, M., Garde, G., Génova-Santos, R., Gomez, A., Gómez-Renasco, M. F., Goupy, J., Hoarau, C., Hoyland, R., Lagache, G., Marpaud, J., Marton, M., Monfardini, A., Peel, M. W., Pisano, G., Ponthieu, N., Rebolo, R., Roudier, S., Rubiño-Martín, J. A., Tourres, D., Tucker, C., and Vescovi, C.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: Context. Wide-field spectrometers are needed to deal with current astrophysical challenges that require multiband observations at millimeter wavelengths. An example of these is the KIDs Interferometer Spectrum Survey (KISS), which uses two arrays of kinetic inductance detectors (KIDs) coupled to a Martin-Puplett interferometer (MPI). KISS has a wide instantaneous field of view (1 deg in diameter) and a spectral resolution up to 1.45 GHz in the 120-180 GHz electromagnetic band. The instrument is installed on the 2.25 m Q-U-I JOint TEnerife telescope in Teide Observatory (Tenerife, Canary Islands), at an altitude of 2395 m above sea level. Aims. This work presents an original readout modulation method developed to improve the sky signal reconstruction accuracy for types of instruments for which a fast sampling frequency is required both to remove atmospheric fluctuations and to perform full spectroscopic measurements on each sampled sky position. Methods. We first demonstrate the feasibility of this technique using simulations. Then, we apply such a scheme to on-sky calibration. Results. We show that the sky signal can be reconstructed to better than 0.5% for astrophysical sources, and to better than 2% for large background variations such as in "skydip", in an ideal noiseless scenario. The readout modulation method is validated by observations on-sky during the KISS commissioning campaign. Conclusions. We conclude that accurate photometry can be obtained for future KID-based MPI., Comment: 11 pages, 10 figures, accepted for publication in A&A
Published: 2021
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115. Perception of Security by Tourism Service Providers: The Case of Acapulco, Mexico

Author: Nájera, Carmen Exchel Cliche, Soulé, Karla Rosalba Anzaldúa, Almazán, Mirella Saldaña, Adame, Arely Adriana Almazán, and Katsoni, Vicky, editor
Published: 2023
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116. Shade coffee plantations favor specialization, decrease robustness and increase foraging in hummingbird-plant networks

Author: Ana I. López-Flores, Claudia I. Rodríguez-Flores, María del Coro Arizmendi, Víctor Rosas-Guerrero, and R. Carlos Almazán-Núñez
Subjects: Hummingbird-plant interaction, Late-successional forest, Cattle pastures, Specialist hummingbirds, Cloud forest, Mexico, Ecology, QH540-549.5, General. Including nature conservation, geographical distribution, QH1-199.5
Abstract: Agroforestry systems, such as shade coffee plantations, favor the maintenance of woody vegetation, which promotes the presence of pollinators such as hummingbirds. Many shade coffee plantations in Mesoamerica have been abandoned due to the fall in coffee prices and undergone succession processes that increase vegetation complexity. Alternatively, they have been replaced by cattle pastures, which negatively affect hummingbird-plant interactions. Here, we describe the structure of hummingbird-plant interaction networks in three types of land use―late-successional forests, coffee plantations, and cattle pastures―that were derived from a cloud forest in southern Mexico. For one year (2019–2020), we collected bimonthly quantitative data on hummingbird-plant interactions for each type of land use. We found that the network of each land use had a heterogeneous structure, and most species had few linkages. The late forests and coffee plantations had more species, pairs of interactions, and modularity than the cattle pastures. The cattle pasture network had the greatest robustness due to the presence of generalist hummingbirds, which are important for network cohesion in a great disturbance scenario. Furthermore, hummingbird visits were influenced by plant traits, such as foliage height diversity. The study findings suggest that the conversion of natural habitats have implications for the conservation of plant-pollinator interactions and that generalist pollinator species are key to disturbance resiliency.
Published: 2024
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117. Hans Kelsen, Professor at the University of Barcelona

Author: Jesús Muñoz Almazán
Subjects: Jurisprudence. Philosophy and theory of law, K201-487
Abstract: Recently found documents show that, in June 1933, when the persecution of Jews in Germany was forcing Hans Kelsen to leave the country, the University of Barcelona appointed him professor of the Faculty of Law. The study of the documents allows us to point to José Ramón Xirau, Full Professor of Procedural Law, Dean of the Faculty and one of the main promoters of the project of autonomy of the University of Barcelona, as the one who made this appointment possible.
Published: 2023
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118. Standard precautions compliance and its associated factors among nurses in Kazakhstan: A cross-sectional study

Author: Cruz, Jonas P., Almazan, Joseph U., Kuntuganova, Anargul, Syzdykova, Alma, Danebek, Kurmet, and Agazhayeva, Gaukhar
Published: 2024
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119. Ongoing declines for the world’s amphibians in the face of emerging threats

Author: Luedtke, Jennifer A., Chanson, Janice, Neam, Kelsey, Hobin, Louise, Maciel, Adriano O., Catenazzi, Alessandro, Borzée, Amaël, Hamidy, Amir, Aowphol, Anchalee, Jean, Anderson, Sosa-Bartuano, Ángel, Fong G., Ansel, de Silva, Anslem, Fouquet, Antoine, Angulo, Ariadne, Kidov, Artem A., Muñoz Saravia, Arturo, Diesmos, Arvin C., Tominaga, Atsushi, Shrestha, Biraj, Gratwicke, Brian, Tjaturadi, Burhan, Martínez Rivera, Carlos C., Vásquez Almazán, Carlos R., Señaris, Celsa, Chandramouli, S. R., Strüssmann, Christine, Cortez Fernández, Claudia Fabiola, Azat, Claudio, Hoskin, Conrad J., Hilton-Taylor, Craig, Whyte, Damion L., Gower, David J., Olson, Deanna H., Cisneros-Heredia, Diego F., Santana, Diego José, Nagombi, Elizah, Najafi-Majd, Elnaz, Quah, Evan S. H., Bolaños, Federico, Xie, Feng, Brusquetti, Francisco, Álvarez, Francisco S., Andreone, Franco, Glaw, Frank, Castañeda, Franklin Enrique, Kraus, Fred, Parra-Olea, Gabriela, Chaves, Gerardo, Medina-Rangel, Guido F., González-Durán, Gustavo, Ortega-Andrade, H. Mauricio, Machado, Iberê F., Das, Indraneil, Dias, Iuri Ribeiro, Urbina-Cardona, J. Nicolas, Crnobrnja-Isailović, Jelka, Yang, Jian-Huan, Jianping, Jiang, Wangyal, Jigme Tshelthrim, Rowley, Jodi J. L., Measey, John, Vasudevan, Karthikeyan, Chan, Kin Onn, Gururaja, Kotambylu Vasudeva, Ovaska, Kristiina, Warr, Lauren C., Canseco-Márquez, Luis, Toledo, Luís Felipe, Díaz, Luis M., Khan, M. Monirul H., Meegaskumbura, Madhava, Acevedo, Manuel E., Napoli, Marcelo Felgueiras, Ponce, Marcos A., Vaira, Marcos, Lampo, Margarita, Yánez-Muñoz, Mario H., Scherz, Mark D., Rödel, Mark-Oliver, Matsui, Masafumi, Fildor, Maxon, Kusrini, Mirza D., Ahmed, Mohammad Firoz, Rais, Muhammad, Kouamé, N’Goran G., García, Nieves, Gonwouo, Nono Legrand, Burrowes, Patricia A., Imbun, Paul Y., Wagner, Philipp, Kok, Philippe J. R., Joglar, Rafael L., Auguste, Renoir J., Brandão, Reuber Albuquerque, Ibáñez, Roberto, von May, Rudolf, Hedges, S. Blair, Biju, S. D., Ganesh, S. R., Wren, Sally, Das, Sandeep, Flechas, Sandra V., Ashpole, Sara L., Robleto-Hernández, Silvia J., Loader, Simon P., Incháustegui, Sixto J., Garg, Sonali, Phimmachak, Somphouthone, Richards, Stephen J., Slimani, Tahar, Osborne-Naikatini, Tamara, Abreu-Jardim, Tatianne P. F., Condez, Thais H., De Carvalho, Thiago R., Cutajar, Timothy P., Pierson, Todd W., Nguyen, Truong Q., Kaya, Uğur, Yuan, Zhiyong, Long, Barney, Langhammer, Penny, and Stuart, Simon N.
Published: 2023
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120. Europium (III) sorption on zirconium diphosphate functionalized with oxalic acid

Author: González, Nidia García, Regil, Eduardo Ordoñez, Torres, María-Guadalupe Almazán, and Morales, Isai Castañeda
Published: 2023
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121. Moderate-intensity continuous training and high-intensity interval training modulate the composition of the oral microbiota of elderly adults: Randomized controlled trial

Author: Lavilla-Lerma, María Leyre, Aibar-Almazán, Agustín, Martínez-Amat, Antonio, Jiménez-García, José Daniel, and Hita-Contreras, Fidel
Published: 2024
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122. COPD patient profiles in primary care. Referral criteria

Author: Trillo-Calvo, E., de Miguel Díez, J., González Villaescusa, C., Panero Hidalgo, P., Cimas Hernando, J.E., Villanueva Pérez, M., Plaza Zamora, F.J., Sanz Almazán, M., and Figueira-Gonçalves, J.M.
Published: 2024
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123. Evaluation of succulent plants Echeveria elegans as a biomonitor of heavy metals and radionuclides

Author: Ortiz-Oliveros, H.B., Mendoza-Guzmán, M.M., Zarazúa-Ortega, G., Lara-Almazán, N., Mestizo-Gutiérrez, S.L., and González-Ruíz, A.
Published: 2024
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124. Static and dynamic experimental validations of a frictional isolator with improved internal lateral impact behavior

Author: Auad, Gaspar, Almazán, José L., Tapia, Nicolás, and Quizanga, Diego
Published: 2024
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125. Measurement of the Xe136 two-neutrino double-β-decay half-life via direct background subtraction in NEXT

Author: Novella, P, Sorel, M, Usón, A, Adams, C, Almazán, H, Álvarez, V, Aparicio, B, Aranburu, AI, Arazi, L, Arnquist, IJ, Ayet, S, Azevedo, CDR, Bailey, K, Ballester, F, Benlloch-Rodríguez, JM, Borges, FIGM, Bounasser, S, Byrnes, N, Cárcel, S, Carrión, JV, Cebrián, S, Church, E, Conde, CAN, Contreras, T, Cossío, FP, Denisenko, AA, Díaz, G, Díaz, J, Dickel, T, Escada, J, Esteve, R, Fahs, A, Felkai, R, Fernandes, LMP, Ferrario, P, Ferreira, AL, Foss, FW, Freitas, EDC, Freixa, Z, Generowicz, J, Goldschmidt, A, Gómez-Cadenas, JJ, González, R, González-Díaz, D, Guenette, R, Gutiérrez, RM, Haefner, J, Hafidi, K, Hauptman, J, Henriques, CAO, Morata, JA Hernando, Herrero-Gómez, P, Herrero, V, Ho, J, Ifergan, Y, Jones, BJP, Kekic, M, Labarga, L, Laing, A, Larizgoitia, L, Lebrun, P, Gutierrez, D Lopez, López-March, N, Losada, M, Mano, RDP, Martín-Albo, J, Martínez, A, Martínez-Lema, G, Martínez-Vara, M, McDonald, AD, Meziani, ZE, Mistry, K, Monrabal, F, Monteiro, CMB, Mora, FJ, Vidal, J Muñoz, Navarro, K, Nygren, DR, Oblak, E, Odriozola-Gimeno, M, Palmeiro, B, Para, A, Pérez, J, Querol, M, Raymond, A, Redwine, AB, Renner, J, Ripoll, L, Rivilla, I, García, Y Rodríguez, Rodríguez, J, Rogero, C, Rogers, L, Romeo, B, Romo-Luque, C, Santos, FP, dos Santos, JMF, Simón, A, Stanford, C, and Teixeira, JMR
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Nuclear and plasma physics
Abstract: We report a measurement of the half-life of the Xe136 two-neutrino double-β decay performed with a novel direct-background-subtraction technique. The analysis relies on the data collected with the NEXT-White detector operated with Xe136-enriched and Xe136-depleted xenon, as well as on the topology of double-electron tracks. With a fiducial mass of only 3.5 kg of Xe, a half-life of 2.34-0.46+0.80(stat)-0.17+0.30(sys)×1021yr is derived from the background-subtracted energy spectrum. The presented technique demonstrates the feasibility of unique background-model-independent neutrinoless double-β-decay searches.
Published: 2022

126. Joint Measurement of the $^{235}$U Antineutrino Spectrum by Prospect and Stereo

Author: Almazán, H., Andriamirado, M., Balantekin, A. B., Band, H. R., Bass, C. D., Bergeron, D. E., Bernard, L., Blanchet, A., Bonhomme, A., Bowden, N. S., Bryan, C. D., Buck, C., Classen, T., Conant, A. J., Deichert, G., Sanchez, P. del Amo, Delgado, A., Diwan, M. V., Dolinski, M. J., Atmani, I. El, Erickson, A., Foust, B. T., Gaison, J. K., Galindo-Uribarri, A., Gilbert, C. E., Hans, S., Hansell, A. B., Heeger, K. M., Heffron, B., Jaffe, D. E., Jayakumar, S., Ji, X., Jones, D. C., Koblanski, J., Kyzylova, O., Labit, L., Lamblin, J., Lane, C. E., Langford, T. J., LaRosa, J., Letourneau, A., Lhuillier, D., Licciardi, M., Lindner, M., Littlejohn, B. R., Lu, X., Maricic, J., Materna, T., Mendenhall, M. P., Meyer, A. M., Milincic, R., Mueller, P. E., Mumm, H. P., Napolitano, J., Neilson, R., Nikkel, J. A., Nour, S., Palomino, J. L., Pessard, H., Pushin, D. A., Qian, X., Réal, J. -S., Ricol, J. -S., Roca, C., Rogly, R., Rosero, R., Salagnac, T., Savu, V., Schoppmann, S., Searles, M., Sergeyeva, V., Soldner, T., Stutz, A., Surukuchi, P. T., Tyra, M. A., Varner, R. L., Venegas-Vargas, D., Vialat, M., Weatherly, P. B., White, C., Wilhelmi, J., Woolverton, A., Yeh, M., Zhang, C., and Zhang, X.
Subjects: Nuclear Experiment, High Energy Physics - Experiment
Abstract: The PROSPECT and STEREO collaborations present a combined measurement of the pure $^{235}$U antineutrino spectrum, without site specific corrections or detector-dependent effects. The spectral measurements of the two highest precision experiments at research reactors are found to be compatible with $\chi^2/\mathrm{ndf} = 24.1/21$, allowing a joint unfolding of the prompt energy measurements into antineutrino energy. This $\bar{\nu}_e$ energy spectrum is provided to the community, and an excess of events relative to the Huber model is found in the 5-6 MeV region. When a Gaussian bump is fitted to the excess, the data-model $\chi^2$ value is improved, corresponding to a $2.4\sigma$ significance.
Published: 2021
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127. Newborn Screening for Sickle Cell Disease in Catalonia between 2015 and 2022—Epidemiology and Impact on Clinical Events

Author: José Manuel González de Aledo-Castillo, Ana Argudo-Ramírez, David Beneitez-Pastor, Anna Collado-Gimbert, Francisco Almazán Castro, Sílvia Roig-Bosch, Anna Andrés-Masó, Anna Ruiz-Llobet, Georgina Pedrals-Portabella, David Medina-Santamaria, Gemma Nadal-Rey, Marina Espigares-Salvia, Maria Teresa Coll-Sibina, Marcelina Algar-Serrano, Montserrat Torrent-Español, Pilar Leoz-Allegretti, Anabel Rodríguez-Pebé, Marta García-Bernal, Elisabet Solà-Segura, Amparo García-Gallego, Blanca Prats-Viedma, Rosa María López-Galera, Abraham J. Paredes-Fuentes, Sonia Pajares García, Giovanna Delgado-López, Adoración Blanco-Álvarez, Bárbara Tazón-Vega, Cristina Díaz de Heredia, María del Mar Mañú-Pereira, José Luis Marín-Soria, Judit García-Villoria, Pablo Velasco-Puyó, and on behalf of the Sickle Cell Disease Newborn Screening Group of Catalonia
Subjects: sickle cell disease, hemoglobinopathies, newborn screening, clinical events, treatment intervention, Pediatrics, RJ1-570
Abstract: In 2015, Catalonia introduced sickle cell disease (SCD) screening in its newborn screening (NBS) program along with standard-of-care treatments like penicillin, hydroxyurea, and anti-pneumococcal vaccination. Few studies have assessed the clinical impact of introducing NBS programs on SCD patients. We analyzed the incidence of SCD and related hemoglobinopathies in Catalonia and the change in clinical events occurring after introducing NBS. Screening 506,996 newborns from 2015 to 2022, we conducted a retrospective multicenter study including 100 screened (SG) and 95 unscreened (UG) SCD patients and analyzed SCD-related clinical events over the first six years of life. We diagnosed 160 cases of SCD, with an incidence of 1 in 3169 newborns. The SG had a significantly lower median age at diagnosis (0.1 y vs. 1.68 y, p < 0.0001), and initiated penicillin prophylaxis (0.12 y vs. 1.86 y, p < 0.0001) and hydroxyurea treatment earlier (1.42 y vs. 4.5 y, p < 0.0001). The SG experienced fewer median SCD-related clinical events (vaso-occlusive crisis, acute chest syndrome, infections of probable bacterial origin, acute anemia requiring transfusion, acute splenic sequestration, and pathological transcranial Doppler echography) per year of follow-up (0.19 vs. 0.77, p < 0.0001), a reduced number of annual emergency department visits (0.37 vs. 0.76, p < 0.0001), and fewer hospitalizations (0.33 vs. 0.72, p < 0.0001). SCD screening in Catalonia’s NBS program has effectively reduced morbidity and improved affected children’s quality of life.
Published: 2024
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128. Ferulic Acid and Clinoptilolite Affect In Vitro Rumen Fermentation Characteristics and Bacterial Abundance

Author: Ana Tánori-Lozano, M. Ángeles López-Baca, Adriana Muhlia-Almazán, Maricela Montalvo-Corral, Araceli Pinelli-Saavedra, Thalia Y. Islava-Lagarda, José Luis Dávila-Ramírez, Martín Valenzuela-Melendres, and Humberto González-Rios
Subjects: zeolite, phytochemical, rumen fermentation, rumen microbiome, Fermentation industries. Beverages. Alcohol, TP500-660
Abstract: This study evaluated the effects of clinoptilolite (CTL) and ferulic acid (FA) supplementation on in vitro ruminal fermentation characteristics, gas production, and bacterial abundance. Treatments were arranged in a 2 × 2 factorial design (FA: 0 or 300 ppm; CTL: 0 or 1%) with repeated measures over time (2, 4, 8, 12, 24, 36, 48, and 72 h). Throughout the incubation period, the CTL and FAZ treatments recorded the highest pH values (p ≤ 0.05), maintaining levels closest to neutrality after 72 h. After 48 and 72 h, FA and CTL decreased (p ≤ 0.05) the ammonia concentrations while increasing (p ≤ 0.05) acetate and propionate. The methane, butyrate, and iso-VFA concentrations were unaffected (p > 0.05) by any treatment. FA increased the total gas production throughout the experimental period (p ≤ 0.05). Additionally, FA and CTL significantly reduced the relative abundance of Ruminococcus albus and Streptococcus bovis (p ≤ 0.05), while no significant effects were observed for Selenomonas ruminantium (p > 0.05). These findings suggest that both additives can positively modify the rumen fermentation characteristics and microbial composition, which could significantly contribute to animal nutrition by providing a promising strategy for enhancing rumen fermentation.
Published: 2024
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129. Overview of Recombinant Tick Vaccines and Perspectives on the Use of Plant-Made Vaccines to Control Ticks of Veterinary Importance

Author: Edgar Trujillo, Abel Ramos-Vega, Elizabeth Monreal-Escalante, Consuelo Almazán, and Carlos Angulo
Subjects: veterinary diseases, immune system, innovative vaccine technology, oral delivery, animal health, Medicine
Abstract: Ticks are obligate hematophagous ectoparasites that affect animals, and some of them transmit a wide range of pathogens including viruses, bacteria, and protozoa to both animals and humans. Several vaccines have shown immunogenicity and protective efficacy against ticks in animal models and definitive hosts. After several decades on anti-tick vaccine research, only a commercial vaccine based on a recombinant antigen is currently available. In this context, plants offer three decades of research and development on recombinant vaccine production to immunize hosts and as a delivery vehicle platform. Despite the experimental advances in plant-made vaccines to control several parasitosis and infectious diseases, no vaccine prototype has been developed against ticks. This review examines a panorama of ticks of veterinary importance, recombinant vaccine experimental developments, plant-made vaccine platforms, and perspectives on using this technology as well as the opportunities and limitations in the field of tick vaccine research.
Published: 2024
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130. Determination of the Relative Profile of Velocity and Acceleration in Semi-Professional Soccer Players: A Cross-Sectional Study

Author: Charles Cotteret, Jaime Prieto-Bermejo, Jaime Almazán Polo, and Sergio L. Jiménez-Saiz
Subjects: acceleration profile, football, GPS technology, running speed, starting speed, soccer playing positions, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
Abstract: The velocity and acceleration of a soccer player varies depending on the specific demands of the field position as well as individual characteristics, establishing the need to determine relative profiles by position. A cross-sectional study was conducted in 18 semi-professional soccer players to determine (i) the specific demands of external load according to playing position, (ii) distances covered at different intensities and the number of sprints, and (iii) the number of accelerations at moderate and high intensity. GPS tracking systems were used to collect data, and the relative acceleration profiles were analyzed based on initial velocity (0–7 km/h; 7.1–14.3 km/h; >14.3 km/h), intensity (moderate 50–75% and high > 75% of maximal acceleration), number of sprints/accelerations, and distance covered. Additionally, relative speed profiles were evaluated through the distance covered at moderate intensity (40–60% Vmax), high intensity (60–75.5% Vmax), very high intensity (>75.5% Vmax), total distance, and number of sprints. Statistically significant differences were observed in the distance covered at moderate and high intensity (midfielders), distance covered sprinting (center backs), and acceleration at moderate and high intensity in all positions (p < 0.05). These findings will enhance the monitoring of external loading strategies and prescription of specific training exercises for soccer players based on their respective playing position, ultimately contributing to optimized performance.
Published: 2024
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131. Mortality-Associated Factors in a Traumatic Brain Injury Population in Mexico

Author: Erick Martínez-Herrera, Evelyn Galindo-Oseguera, Juan Castillo-Cruz, Claudia Erika Fuentes-Venado, Gilberto Adrián Gasca-López, Claudia C. Calzada-Mendoza, Esther Ocharan-Hernández, Carlos Alberto Zúñiga-Cruz, Eunice D. Farfán-García, Alfredo Arellano-Ramírez, and Rodolfo Pinto-Almazán
Subjects: traumatic brain injury, seizures, aggregate limb trauma, diabetes mellitus, heart disease, Biology (General), QH301-705.5
Abstract: Background: Traumatic brain injury (TBI) is a major cause of death and disability, with a rising incidence in recent years. Factors such as age, sex, hypotension, low score on the Glasgow Coma Scale, use of invasive mechanical ventilation and vasopressors, etc., have been associated with mortality caused by TBI. The aim of this study was to identify the clinical and sociodemographic characteristics that influence the mortality or survival of patients with TBI in a tertiary care hospital in Mexico. Methods: A sample of 94 patients aged 18 years or older, from both sexes, with an admitting diagnosis of mild-to-severe head trauma, with initial prehospital treatment, was taken. Data were extracted from the Single Registry of Patients with TBI at the Ixtapaluca Regional High Specialty Hospital (HRAEI). Normality tests were used to decide on the corresponding statistical analysis. Results: No factors associated with mortality were found; however, survival analysis showed that the presence of seizures, aggregate limb trauma, and subjects with diabetes mellitus, heart disease or patients with four concomitant comorbidities had 100% mortality. In addition, having seizures in the prehospital setting increased the risk of mortality four times. Although they did not have a direct association with mortality, they significantly decreased survival. A larger sample size is probably required to obtain an association with mortality. Conclusions: These results reflect the severity of the clinical situation in this population and, although no risk factors were identified, they enlighten us about the conditions presented by patients who died.
Published: 2024
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132. Effect of Chronic Tibolone Administration on Memory and Choline Acetyltransferase and Tryptophan Hydroxylase Content in Aging Mice

Author: Tzayaka Castillo-Mendieta, Guadalupe Bautista-Poblet, Angélica Coyoy-Salgado, Emily L. Castillo-García, Rodolfo Pinto-Almazán, Claudia Erika Fuentes-Venado, Teresa Neri-Gómez, and Christian Guerra-Araiza
Subjects: aging mice, tibolone, memory, hippocampus, tryptophan hydroxylase, choline acetyltransferase, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract: Gonadal steroids exert different effects on the central nervous system (CNS), such as preserving neuronal function and promoting neuronal survival. Estradiol, progesterone, and testosterone reduce neuronal loss in the CNS in animal models of neurodegeneration. However, hormone replacement therapy has been associated with higher rates of endometrial, prostate, and breast cancer. Tibolone (TIB), the metabolites of which show estrogenic and progestogenic effects, is an alternative to reduce this risk. However, the impact of TIB on memory and learning, as well as on choline acetyltransferase (ChAT) and tryptophan hydroxylase (TPH) levels in the hippocampus of aging males, is unknown. We administered TIB to aged C57BL/6J male mice at different doses (0.01 or 1.0 mg/kg per day for 12 weeks) and evaluated its effects on memory and learning and the content of ChAT and TPH. We assessed memory and learning with object recognition and elevated T-maze tasks. Additionally, we determined ChAT and TPH protein levels in the hippocampus by Western blotting. TIB administration increased the percentage of time spent on the novel object in the object recognition task. In addition, the latency of leaving the enclosed arm increased in both TIB groups, suggesting an improvement in fear-based learning. We also observed decreased ChAT content in the group treated with the 0.01 mg/kg TIB dose. In the case of TPH, no changes were observed with either TIB dose. These results show that long-term TIB administration improves memory without affecting locomotor activity and modulates cholinergic but not serotonergic systems in the hippocampus of aged male mice.
Published: 2024
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133. Cross-Cultural Adaptation and Clinical Validation of the Mini Sarcopenia Risk Assessment Questionnaire in Community-Dwelling Spanish Older Adults

Author: Inés Moreno-Sánchez, Agustín Aibar-Almazán, María del Carmen Carcelén-Fraile, Ana Belén Parra-Díaz, Indalecio Sánchez-Montesinos García, Marcelina Sánchez-Alcalá, Javier Cano-Sánchez, and Fidel Hita-Contreras
Subjects: sarcopenia, screening, reliability, validation, Medicine (General), R5-920
Abstract: (1) Background: The aim was to analyze the reliability and validity of the Spanish version of the Mini Sarcopenia Risk Assessment (MSRA) in older adults. (2) Methods: A total of 136 participants (72.24 ± 5.21 years, 68.38% women) took part in the study. The MSRA includes two questionnaires with seven (MSRA-7) and five items (MSRA-5). First, reliability (inter-rater and test–retest) of the Spanish MSRA was studied, and then the total scores were compared with the presence of sarcopenia according to three different diagnostic criteria and with other parameters related to sarcopenia (clinical validation). (3) Results: The analysis showed excellent inter-rater and test–retest reliability. As for the clinical validation, and regardless of the criteria, both questionnaires had a high sensitivity (81.82–88.89% for the MSRA-5 and 90.91–94.44% for the MSRA-7), while the MSRA-5 showed a better specificity (32.00–33.90%) than the MSRA-7 (20.80–22.88%). Predictive positive values ranged from 9.57–17.02% (MSRA-5) and 9.17–15.54% (MSRA-7), while predictive negative values were high for both the MSRA-5 (95.24%) and the MSRA-7 (96.30–96.43%). The accuracy was better for the MSRA-5 (36.03–41.18%) than the MSRA-7 (26.47–32.35%), as well as the area under the curve (0.67–0.76 vs. 0.65–0.73, respectively). Higher MSRA-5 and MSRA-7 total scores significantly correlated with greater muscle strength, quantity and gait speed. (4) Conclusions: The adaptation of the Spanish MSRA questionnaires was successfully performed, and they are reliable and clinically valid tools for assessing sarcopenia.
Published: 2024
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134. Using the Nintendo™ Wii to Improve Physical Function and Reduce the Risk of Falls in Older Adults: A Randomized Controlled Clinical Trial

Author: María del Carmen Carcelén-Fraile, Agustín Aibar-Almazán, Fidel Hita-Contreras, Marcelina Sánchez-Alcalá, Ana Belén Parra-Díaz, Aday Infante-Guedes, and Yolanda Castellote-Caballero
Subjects: balance, muscle strength, flexibility, training, older adults, Chemical technology, TP1-1185
Abstract: (1) Background: Numerous exercise programs that improve physical capacity and the risk of falls in older adults have been proposed with varying degrees of success. A novel approach may be to use a video game system that uses real-time force feedback to train older adults. The aim of this study was to evaluate the effects of a Nintendo™ Wii-based exercise program on physical function and risk of falls in older people. (2) Methods: This 12-week randomized controlled clinical trial involved 73 participants: 36 individuals participating in a control group (CG) and 37 in an experimental group (EG) participating in a combined program. Balance was measured using the Tinetti scale, flexibility was assessed with the back scratch test and the sit-and-reach test, and lower body strength was assessed with the 30 s chair stand-up test. (3) Results: The results of this study show significant improvements in balance, gait, flexibility, and strength of the lower limbs compared to a control group. (4) Conclusions: A Nintendo™ Wii-based exercise program for seniors produces improvements in the physical health of older adults. These improvements highlight the importance of integrating physical exercise through video games as an effective strategy to improve the general health and quality of life of older adults.
Published: 2024
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135. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author: Ferrari, Alize J, Santomauro, Damian Francesco, Aali, Amirali, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbastabar, Hedayat, Abd ElHafeez, Samar, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdollahi, Arash, Abdullahi, Auwal, Abegaz, Kedir Hussein, Abeldaño Zuñiga, Roberto Ariel, Aboagye, Richard Gyan, Abolhassani, Hassan, Abreu, Lucas Guimarães, Abualruz, Hasan, Abu-Gharbieh, Eman, Abu-Rmeileh, Niveen ME, Ackerman, Ilana N, Addo, Isaac Yeboah, Addolorato, Giovanni, Adebiyi, Akindele Olupelumi, Adepoju, Abiola Victor, Adewuyi, Habeeb Omoponle, Afyouni, Shadi, Afzal, Saira, Afzal, Sina, Agodi, Antonella, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Shahzaib, Ahmed, Ali, Ahmed, Luai A, Ahmed, Muktar Beshir, Ajami, Marjan, Akinosoglou, Karolina, Akkaif, Mohammed Ahmed, Al Hasan, Syed Mahfuz, Alalalmeh, Samer O, Al-Aly, Ziyad, Albashtawy, Mohammed, Aldridge, Robert W, Alemu, Meseret Desalegn, Alemu, Yihun Mulugeta, Alene, Kefyalew Addis, Al-Gheethi, Adel Ali Saeed, Alharrasi, Maryam, Alhassan, Robert Kaba, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Al-Marwani, Sabah, Almazan, Joseph Uy, Alomari, Mahmoud A, Al-Omari, Basem, Altaany, Zaid, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Alwafi, Hassan, Al-Wardat, Mohammad Sami, Al-Worafi, Yaser Mohammed, Aly, Safwat, Alzoubi, Karem H, Amare, Azmeraw T, Amegbor, Prince M, Ameyaw, Edward Kwabena, Amin, Tarek Tawfik, Amindarolzarbi, Alireza, Amiri, Sohrab, Amugsi, Dickson A, Ancuceanu, Robert, Anderlini, Deanna, Anderson, David B, Andrade, Pedro Prata, Andrei, Catalina Liliana, Ansari, Hossein, Antony, Catherine M, Anwar, Saleha, Anwar, Sumadi Lukman, Anwer, Razique, Anyanwu, Philip Emeka, Arab, Juan Pablo, Arabloo, Jalal, Arafat, Mosab, Araki, Daniel T, Aravkin, Aleksandr Y, Arkew, Mesay, Armocida, Benedetta, Arndt, Michael Benjamin, Arooj, Mahwish, Artamonov, Anton A, Aruleba, Raphael Taiwo, Arumugam, Ashokan, Ashbaugh, Charlie, Ashemo, Mubarek Yesse, Ashraf, Muhammad, Asika, Marvellous O, Askari, Elaheh, Astell-Burt, Thomas, Athari, Seyyed Shamsadin, Atorkey, Prince, Atout, Maha Moh'd Wahbi, Atreya, Alok, Aujayeb, Avinash, Ausloos, Marcel, Avan, Abolfazl, Awotidebe, Adedapo Wasiu, Awuviry-Newton, Kofi, Ayala Quintanilla, Beatriz Paulina, Ayuso-Mateos, Jose L, Azadnajafabad, Sina, Azevedo, Rui M S, Babu, Abraham Samuel, Badar, Muhammad, Badiye, Ashish D, Baghdadi, Soroush, Bagheri, Nasser, Bah, Sulaiman, Bai, Ruhai, Baker, Jennifer L, Bakkannavar, Shankar M, Bako, Abdulaziz T, Balakrishnan, Senthilkumar, Bam, Kiran, Banik, Palash Chandra, Barchitta, Martina, Bardhan, Mainak, Bardideh, Erfan, Barker-Collo, Suzanne Lyn, Barqawi, Hiba Jawdat, Barrow, Amadou, Barteit, Sandra, Barua, Lingkan, Bashiri Aliabadi, Somaye, Basiru, Afisu, Basu, Sanjay, Basu, Saurav, Bathini, Prapthi Persis, Batra, Kavita, Baune, Bernhard T, Bayileyegn, Nebiyou Simegnew, Behnam, Babak, Behnoush, Amir Hossein, Beiranvand, Maryam, Bejarano Ramirez, Diana Fernanda, Bell, Michelle L, Bello, Olorunjuwon Omolaja, Beloukas, Apostolos, Bensenor, Isabela M, Berezvai, Zombor, Bernabe, Eduardo, Bernstein, Robert S, Bettencourt, Paulo J G, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhandari, Dinesh, Bhargava, Ashish, Bhaskar, Sonu, Bhat, Vivek, Bhatti, Gurjit Kaur, Bhatti, Jasvinder Singh, Bhatti, Manpreet S, Bhatti, Rajbir, Bhutta, Zulfiqar A, Bikbov, Boris, Bishai, Jessica Devin, Bisignano, Catherine, Bitra, Veera R, Bjørge, Tone, Bodolica, Virginia, Bodunrin, Aadam Olalekan, Bogale, Eyob Ketema, Bonakdar Hashemi, Milad, Bonny, Aime, Bora Basara, Berrak, Borhany, Hamed, Boxe, Christopher, Brady, Oliver J, Bragazzi, Nicola Luigi, Braithwaite, Dejana, Brant, Luisa C, Brauer, Michael, Breitner, Susanne, Brenner, Hermann, Brown, Julie, Brugha, Traolach, Bulamu, Norma B, Buonsenso, Danilo, Burkart, Katrin, Burns, Richard A, Busse, Reinhard, Bustanji, Yasser, Butt, Zahid A, Byun, Justin, Caetano dos Santos, Florentino Luciano, Calina, Daniela, Cámera, Luis Alberto, Campos-Nonato, Ismael R, Cao, Chao, Capodici, Angelo, Carr, Sinclair, Carreras, Giulia, Carugno, Andrea, Carvalho, Márcia, Castaldelli-Maia, Joao Mauricio, Castañeda-Orjuela, Carlos A, Castelpietra, Giulio, Catapano, Alberico L, Cattaruzza, Maria Sofia, Caye, Arthur, Cegolon, Luca, Cembranel, Francieli, Cenderadewi, Muthia, Cerin, Ester, Chakraborty, Promit Ananyo, Chan, Jeffrey Shi Kai, Chan, Raymond N C, Chandika, Rama Mohan, Chandrasekar, Eeshwar K, Charalampous, Periklis, Chattu, Vijay Kumar, Chatzimavridou-Grigoriadou, Victoria, Chen, Angela W, Chen, An-Tian, Chen, Catherine S, Chen, Haowei, Chen, Nathalie M, Cheng, Esther T W, Chimed-Ochir, Odgerel, Chimoriya, Ritesh, Ching, Patrick R, Cho, William C S, Choi, Sungchul, Chong, Bryan, Chong, Yuen Yu, Choudhari, Sonali Gajanan, Chowdhury, Rajiv, Christensen, Steffan Wittrup McPhee, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eric, Chung, Eunice, Chutiyami, Muhammad, Claassens, Mareli M, Cogen, Rebecca M, Columbus, Alyssa, Conde, Joao, Cortesi, Paolo Angelo, Cousin, Ewerton, Criqui, Michael H, Cruz-Martins, Natália, Dadras, Omid, Dai, Siyu, Dai, Xiaochen, Dai, Zhaoli, Dalaba, Maxwell Ayindenaba, Damiani, Giovanni, Das, Jai K, Das, Saswati, Dashti, Mohsen, Dávila-Cervantes, Claudio Alberto, Davletov, Kairat, De Leo, Diego, Debele, Aklilu Tamire, Debopadhaya, Shayom, DeCleene, Nicole K, Deeba, Farah, Degenhardt, Louisa, Del Bo', Cristian, Delgado-Enciso, Ivan, Demetriades, Andreas K, Denova-Gutiérrez, Edgar, Dervenis, Nikolaos, Desai, Hardik Dineshbhai, Desai, Rupak, Deuba, Keshab, Dhama, Kuldeep, Dharmaratne, Samath Dhamminda, Dhingra, Sameer, Dias da Silva, Diana, Diaz, Daniel, Diaz, Luis Antonio, Diaz, Michael J, Dima, Adriana, Ding, Delaney D, Dirac, M Ashworth, Do, Thao Huynh Phuong, do Prado, Camila Bruneli, Dohare, Sushil, Dominguez, Regina-Mae Villanueva, Dong, Wanyue, Dongarwar, Deepa, D'Oria, Mario, Dorsey, E Ray, Doshmangir, Leila, Dowou, Robert Kokou, Driscoll, Tim Robert, Dsouza, Haneil Larson, Dsouza, Viola, Dube, John, Dumith, Samuel C, Duncan, Bruce B, Duraes, Andre Rodrigues, Duraisamy, Senbagam, Durojaiye, Oyewole Christopher, Dzianach, Paulina Agnieszka, Dziedzic, Arkadiusz Marian, Eboreime, Ejemai, Ebrahimi, Alireza, Edinur, Hisham Atan, Edvardsson, David, Eikemo, Terje Andreas, Eini, Ebrahim, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, El Sayed, Iman, El Tantawi, Maha, Elbarazi, Iffat, Elemam, Noha Mousaad, ElGohary, Ghada Metwally Tawfik, Elhadi, Muhammed, Elmeligy, Omar Abdelsadek Abdou, ELNahas, Gihan, Elshaer, Mohammed, Elsohaby, Ibrahim, Engelbert Bain, Luchuo, Erkhembayar, Ryenchindorj, Eshrati, Babak, Estep, Kara, Fabin, Natalia, Fagbamigbe, Adeniyi Francis, Falzone, Luca, Fareed, Mohammad, Farinha, Carla Sofia e Sá, Faris, MoezAlIslam Ezzat Mahmoud, Faro, Andre, Farrokhi, Pegah, Fatehizadeh, Ali, Fauk, Nelsensius Klau, Feigin, Valery L, Feng, Xiaoqi, Fereshtehnejad, Seyed-Mohammad, Feroze, Abdullah Hamid, Ferreira, Nuno, Ferreira, Paulo H, Fischer, Florian, Flavel, Joanne, Flood, David, Flor, Luisa S, Foigt, Nataliya A, Folayan, Morenike Oluwatoyin, Force, Lisa M, Fortuna, Daniela, Foschi, Matteo, Franklin, Richard Charles, Freitas, Alberto, Fukumoto, Takeshi, Furtado, João M, Gaal, Peter Andras, Gadanya, Muktar A, Gaidhane, Abhay Motiramji, Gaihre, Santosh, Galali, Yaseen, Ganbat, Mandukhai, Gandhi, Aravind P, Ganesan, Balasankar, Ganie, Mohd Ashraf, Ganiyani, Mohammad Arfat, Gardner, William M, Gebi, Tilaye Gebru, Gebregergis, Miglas W, Gebrehiwot, Mesfin, Gebremariam, Tesfay B B, Gebremeskel, Teferi Gebru, Gela, Yibeltal Yismaw, Georgescu, Simona Roxana, Getachew Obsa, Abera, Gething, Peter W, Getie, Molla, Ghadiri, Keyghobad, Ghadirian, Fataneh, Ghailan, Khalid Yaser, Ghajar, Alireza, Ghasemi, MohammadReza, Ghasempour Dabaghi, Ghazal, Ghasemzadeh, Afsaneh, Ghazy, Ramy Mohamed, Gholamrezanezhad, Ali, Ghorbani, Mahsa, Ghotbi, Elena, Gibson, Ruth Margaret, Gill, Tiffany K, Ginindza, Themba G, Girmay, Alem, Glasbey, James C, Göbölös, Laszlo, Godinho, Myron Anthony, Goharinezhad, Salime, Goldust, Mohamad, Golechha, Mahaveer, Goleij, Pouya, Gona, Philimon N, Gorini, Giuseppe, Goulart, Alessandra C, Grada, Ayman, Grivna, Michal, Guan, Shi-Yang, Guarducci, Giovanni, Gubari, Mohammed Ibrahim Mohialdeen, Gudeta, Mesay Dechasa, Guha, Avirup, Guicciardi, Stefano, Gulati, Snigdha, Gulisashvili, David, Gunawardane, Damitha Asanga, Guo, Cui, Gupta, Anish Kumar, Gupta, Bhawna, Gupta, Ishita, Gupta, Mohak, Gupta, Rajeev, Gupta, Veer Bala, Gupta, Vijai Kumar, Gupta, Vivek Kumar, Gutiérrez, Reyna Alma, Habibzadeh, Farrokh, Habibzadeh, Parham, Haddadi, Rasool, Hadi, Najah R, Haep, Nils, Hafezi-Nejad, Nima, Hafiz, Abdul, Hagins, Hailey, Halboub, Esam S, Halimi, Aram, Haller, Sebastian, Halwani, Rabih, Hamilton, Erin B, Hankey, Graeme J, Hannan, Md Abdul, Haque, Md Nuruzzaman, Harapan, Harapan, Haro, Josep Maria, Hartvigsen, Jan, Hasaballah, Ahmed I, Hasan, Ikramul, Hasanian, Mohammad, Hasnain, Md Saquib, Hassan, Amr, Haubold, Johannes, Havmoeller, Rasmus J, Hay, Simon I, Hayat, Khezar, Hebert, Jeffrey J, Hegazi, Omar E, Heidari, Golnaz, Helfer, Bartosz, Hemmati, Mehdi, Hendrie, Delia, Henson, Claire A, Hezam, Kamal, Hiraike, Yuta, Hoan, Nguyen Quoc, Holla, Ramesh, Hon, Julia, Hossain, Md Mahbub, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Hsu, Johnathan M, Huang, Junjie, Hugo, Fernando N, Hushmandi, Kiavash, Hussain, Javid, Hussein, Nawfal R, Huynh, Chantal K, Huynh, Hong-Han, Hwang, Bing-Fang, Iannucci, Vincent C, Ihler, Audrey L, Ikiroma, Adalia I, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Imam, Mohammad Tarique, Immurana, Mustapha, Irham, Lalu Muhammad, Islam, Md Rabiul, Islam, Sheikh Mohammed Shariful, Islami, Farhad, Ismail, Faisal, Ismail, Nahlah Elkudssiah, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie C D, Iyer, Mahalaxmi, Jaafari, Jalil, Jacobsen, Kathryn H, Jadidi-Niaragh, Farhad, Jafarinia, Morteza, Jaggi, Khushleen, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jain, Akhil, Jain, Nityanand, Jairoun, Ammar Abdulrahman, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jatau, Abubakar Ibrahim, Javadov, Sabzali, Javaheri, Tahereh, Jayapal, Sathish Kumar, Jayaram, Shubha, Jee, Sun Ha, Jeganathan, Jayakumar, Jeyakumar, Angeline, Jha, Anil K, Jiang, Heng, Jin, Yinzi, Jonas, Jost B, Joo, Tamas, Joseph, Abel, Joseph, Nitin, Joshua, Charity Ehimwenma, Jozwiak, Jacek Jerzy, Jürisson, Mikk, K, Vaishali, Kaambwa, Billingsley, Kabir, Ali, Kabir, Zubair, Kadashetti, Vidya, Kalani, Rizwan, Kalankesh, Leila R, Kaliyadan, Feroze, Kalra, Sanjay, Kamenov, Kaloyan, Kamyari, Naser, Kanagasabai, Thanigaivelan, Kandel, Himal, Kanmanthareddy, Arun R, Kanmodi, Kehinde Kazeem, Kantar, Rami S, Karaye, Ibraheem M, Karim, Asima, Karimi, Salah Eddin, Karimi, Yeganeh, Kasraei, Hengameh, Kassel, Molly B, Kauppila, Joonas H, Kawakami, Norito, Kayode, Gbenga A, Kazemi, Foad, Kazemian, Sina, Keikavoosi-Arani, Leila, Keller, Cathleen, Kempen, John H, Kerr, Jessica A, Keshtkar, Kamyab, Kesse-Guyot, Emmanuelle, Keykhaei, Mohammad, Khajuria, Himanshu, Khalaji, Amirmohammad, Khalid, Asaad, Khalid, Nauman, Khalilian, Alireza, Khamesipour, Faham, Khan, Asaduzzaman, Khan, Ikramullah, Khan, Maseer, Khan, Moien AB, Khanmohammadi, Shaghayegh, Khatab, Khaled, Khatami, Fatemeh, Khatatbeh, Moawiah Mohammad, Khater, Amir M, Khayat Kashani, Hamid Reza, Khidri, Feriha Fatima, Khodadoust, Elaheh, Khormali, Moein, Khorrami, Zahra, Kifle, Zemene Demelash, Kim, Min Seo, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Knudsen, Ann Kristin Skrindo, Kocarnik, Jonathan M, Kochhar, Sonali, Koh, Hyun Yong, Kolahi, Ali-Asghar, Kompani, Farzad, Koren, Gerbrand, Korzh, Oleksii, Kosen, Soewarta, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Krishna, Varun, Krishnamoorthy, Vijay, Kuate Defo, Barthelemy, Kuddus, Md Abdul, Kuddus, Mohammed, Kuitunen, Ilari, Kulkarni, Vishnutheertha, Kumar, Manasi, Kumar, Nithin, Kumar, Rakesh, Kurmi, Om P, Kusuma, Dian, Kyu, Hmwe Hmwe, La Vecchia, Carlo, Lacey, Ben, Ladan, Muhammad Awwal, Laflamme, Lucie, Lafranconi, Alessandra, Lahariya, Chandrakant, Lai, Daphne Teck Ching, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lallukka, Tea, Lám, Judit, Lan, Qing, Lan, Tuo, Landires, Iván, Lanfranchi, Francesco, Langguth, Berthold, Laplante-Lévesque, Ariane, Larijani, Bagher, Larsson, Anders O, Lasrado, Savita, Lauriola, Paolo, Le, Huu-Hoai, Le, Long Khanh Dao, Le, Nhi Huu Hanh, Le, Trang Diep Thanh, Leasher, Janet L, Ledda, Caterina, Lee, Munjae, Lee, Paul H, Lee, Sang-woong, Lee, Seung Won, Lee, Wei-Chen, Lee, Yo Han, LeGrand, Kate E, Lenzi, Jacopo, Leong, Elvynna, Leung, Janni, Li, Ming-Chieh, Li, Wei, Li, Xiaopan, Li, Yichong, Li, Yongze, Lim, Lee-Ling, Lim, Stephen S, Lindstrom, Megan, Linn, Shai, Liu, Gang, Liu, Runben, Liu, Shiwei, Liu, Wei, Liu, Xiaofeng, Liu, Xuefeng, Llanaj, Erand, Lo, Chun-Han, López-Bueno, Rubén, Loreche, Arianna Maever, Lorenzovici, László, Lozano, Rafael, Lubinda, Jailos, Lucchetti, Giancarlo, Lunevicius, Raimundas, Lusk, Jay B, lv, hengliang, Ma, Zheng Feei, Machairas, Nikolaos, Madureira-Carvalho, Áurea M, Magaña Gómez, Javier A, Maghazachi, Azzam A, Maharjan, Preeti, Mahasha, Phetole Walter, Maheri, Mina, Mahjoub, Soleiman, Mahmoud, Mansour Adam, Mahmoudi, Elham, Majeed, Azeem, Makris, Konstantinos Christos, Malakan Rad, Elaheh, Malhotra, Kashish, Malik, Ahmad Azam, Malik, Iram, Malta, Deborah Carvalho, Manla, Yosef, Mansour, Ali, Mansouri, Pejman, Mansournia, Mohammad Ali, Mantilla Herrera, Ana M, Mantovani, Lorenzo Giovanni, Manu, Emmanuel, Marateb, Hamid Reza, Mardi, Parham, Martinez, Gabriel, Martinez-Piedra, Ramon, Martini, Daniela, Martins-Melo, Francisco Rogerlândio, Martorell, Miquel, Marx, Wolfgang, Maryam, Sharmeen, Marzo, Roy Rillera, Mathangasinghe, Yasith, Mathieson, Stephanie, Mathioudakis, Alexander G, Mattumpuram, Jishanth, Maugeri, Andrea, Mayeli, Mahsa, Mazidi, Mohsen, Mazzotti, Antonio, McGrath, John J, McKee, Martin, McKowen, Anna Laura W, McPhail, Michael A, Mehrabani-Zeinabad, Kamran, Mehrabi Nasab, Entezar, Mekene Meto, Tesfahun, Mendoza, Walter, Menezes, Ritesh G, Mensah, George A, Mentis, Alexios-Fotios A, Meo, Sultan Ayoub, Meresa, Haftu Asmerom, Meretoja, Atte, Meretoja, Tuomo J, Mersha, Abera M, Mestrovic, Tomislav, Mettananda, Kukulege Chamila Dinushi, Mettananda, Sachith, Michalek, Irmina Maria, Miller, Paul Anthony, Miller, Ted R, Mills, Edward J, Minh, Le Huu Nhat, Mirijello, Antonio, Mirrakhimov, Erkin M, Mirutse, Mizan Kiros, Mirza-Aghazadeh-Attari, Mohammad, Mirzaei, Maryam, Mirzaei, Roya, Misganaw, Awoke, Mishra, Ajay Kumar, Mitchell, Philip B, Mittal, Chaitanya, Moazen, Babak, Moberg, Madeline E, Mohamed, Jama, Mohamed, Mouhand F H, Mohamed, Nouh Saad, Mohammadi, Esmaeil, Mohammadi, Soheil, Mohammed, Hussen, Mohammed, Salahuddin, Mohammed, Shafiu, Mohr, Robin M, Mokdad, Ali H, Molinaro, Sabrina, Momtazmanesh, Sara, Monasta, Lorenzo, Mondello, Stefania, Moodi Ghalibaf, AmirAli, Moradi, Maryam, Moradi, Yousef, Moradi-Lakeh, Maziar, Moraga, Paula, Morawska, Lidia, Moreira, Rafael Silveira, Morovatdar, Negar, Morrison, Shane Douglas, Morze, Jakub, Mosapour, Abbas, Mosser, Jonathan F, Mossialos, Elias, Motappa, Rohith, Mougin, Vincent, Mouodi, Simin, Mrejen, Matías, Msherghi, Ahmed, Mubarik, Sumaira, Mueller, Ulrich Otto, Mulita, Francesk, Munjal, Kavita, Murillo-Zamora, Efrén, Murlimanju, BV, Mustafa, Ghulam, Muthu, Sathish, Muzaffar, Muhammad, Myung, Woojae, Nagarajan, Ahamarshan Jayaraman, Naghavi, Pirouz, Naik, Ganesh R, Nainu, Firzan, Nair, Sanjeev, Najmuldeen, Hastyar Hama Rashid, Nangia, Vinay, Naqvi, Atta Abbas, Narayana, Aparna Ichalangod, Nargus, Shumaila, Nascimento, Gustavo G, Nashwan, Abdulqadir J, Nasrollahizadeh, Ali, Nasrollahizadeh, Amir, Natto, Zuhair S, Nayak, Biswa Prakash, Nayak, Vinod C, Nduaguba, Sabina Onyinye, Negash, Hadush, Negoi, Ionut, Negoi, Ruxandra Irina, Nejadghaderi, Seyed Aria, Nesbit, Olivia D, Netsere, Henok Biresaw, Ng, Marie, Nguefack-Tsague, Georges, Ngunjiri, Josephine W, Nguyen, Dang H, Nguyen, Hien Quang, Niazi, Robina Khan, Nikolouzakis, Taxiarchis Konstantinos, Nikoobar, Ali, Nikoomanesh, Fatemeh, Nikpoor, Amin Reza, Nnaji, Chukwudi A, Nnyanzi, Lawrence Achilles, Noman, Efaq Ali, Nomura, Shuhei, Norrving, Bo, Nri-Ezedi, Chisom Adaobi, Ntaios, George, Ntsekhe, Mpiko, Nurrika, Dieta, Nzoputam, Chimezie Igwegbe, Nzoputam, Ogochukwu Janet, Oancea, Bogdan, Odetokun, Ismail A, O'Donnell, Martin James, Oguntade, Ayodipupo Sikiru, Oguta, James Odhiambo, Okati-Aliabad, Hassan, Okeke, Sylvester Reuben, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Olagunju, Andrew T, Olasupo, Omotola O, Olatubi, Matthew Idowu, Oliveira, Gláucia Maria Moraes, Olufadewa, Isaac Iyinoluwa, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Omar, Hany A, Omer, Goran Latif, Omonisi, Abidemi E Emmanuel, Onie, Sandersan, Onwujekwe, Obinna E, Ordak, Michal, Orish, Verner N, Ortega-Altamirano, Doris V, Ortiz, Alberto, Ortiz-Brizuela, Edgar, Osman, Wael M S, Ostroff, Samuel M, Osuagwu, Uchechukwu Levi, Otoiu, Adrian, Otstavnov, Nikita, Otstavnov, Stanislav S, Ouyahia, Amel, Ouyang, Guoqing, Owolabi, Mayowa O, P A, Mahesh Padukudru, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Palicz, Tamás, Palladino, Claudia, Pan, Feng, Pandi-Perumal, Seithikurippu R, Pangaribuan, Helena Ullyartha, Panos, Georgios D, Panos, Leonidas D, Pantea Stoian, Anca Mihaela, Pardhan, Shahina, Parikh, Romil R, Pashaei, Ava, Pasovic, Maja, Passera, Roberto, Patel, Jay, Patel, Sangram Kishor, Patil, Shankargouda, Patoulias, Dimitrios, Patthipati, Venkata Suresh, Pawar, Shrikant, Pazoki Toroudi, Hamidreza, Pease, Spencer A, Peden, Amy E, Pedersini, Paolo, Peng, Minjin, Pensato, Umberto, Pepito, Veincent Christian Filipino, Peprah, Emmanuel K, Peprah, Prince, Perdigão, João, Pereira, Maria Odete, Perianayagam, Arokiasamy, Perico, Norberto, Pesudovs, Konrad, Petermann-Rocha, Fanny Emily, Petri, William A, Pham, 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Theo, and Murray, Christopher J L
Published: 2024
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136. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author: Naghavi, Mohsen, Ong, Kanyin Liane, Aali, Amirali, Ababneh, Hazim S, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasian, Mohammadreza, Abbasi-Kangevari, Mohsen, Abbastabar, Hedayat, Abd ElHafeez, Samar, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed, Abdollahi, Mohammad, Abdollahifar, Mohammad-Amin, Abdoun, Meriem, Abdulah, Deldar Morad, Abdullahi, Auwal, Abebe, Mesfin, Abebe, Samrawit Shawel, Abedi, Aidin, Abegaz, Kedir Hussein, Abhilash, E S, Abidi, Hassan, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Abolmaali, Meysam, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abrha, Woldu Aberhe, Abtahi, Dariush, Abu Rumeileh, Samir, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abu-Rmeileh, Niveen ME, Aburuz, Salahdein, Abu-Zaid, Ahmed, Accrombessi, Manfred Mario Kokou, Adal, Tadele Girum, Adamu, Abdu A, Addo, Isaac Yeboah, Addolorato, Giovanni, Adebiyi, Akindele Olupelumi, Adekanmbi, 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Published: 2024
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137. Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

Author: Vollset, Stein Emil, Ababneh, Hazim S, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abd Al Magied, Abdallah H A, Abd ElHafeez, Samar, Abdelkader, Atef, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdi, Parsa, Abdollahi, Mohammad, Abdoun, Meriem, Abdullahi, Auwal, Abebe, Mesfin, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Absalan, Abdorrahim, Abualruz, Hasan, Abubakar, Bilyaminu, Abukhadijah, Hana Jihad Jihad, Addolorato, Giovanni, Adekanmbi, Victor, Adetunji, Charles Oluwaseun, Adetunji, Juliana Bunmi, Adeyeoluwa, Temitayo Esther, Adha, Rishan, Adhikary, Ripon Kumar, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afrashteh, Fatemeh, Afzal, Muhammad Sohail, Afzal, Saira, Agbozo, Faith, Agodi, Antonella, Agrawal, Anurag, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahlstrom, Austin J, Ahmad, Aqeel, Ahmad, Firdos, Ahmad, Muayyad M, Ahmad, Sajjad, Ahmad, Shahzaib, Ahmed, Anisuddin, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Safoora, Ahmed, Syed Anees, Akinosoglou, Karolina, Akkaif, Mohammed Ahmed, Akrami, Ashley E, Akter, Ema, Al Awaidy, Salah, Al Hasan, Syed Mahfuz, Al Mosa, Amjad S, Al Ta'ani, Omar, Al Zaabi, Omar Ali Mohammed, Alahdab, Fares, Alajlani, Muaaz M, Al-Ajlouni, Yazan, Alalalmeh, Samer O, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Tahiya, Alam, Zufishan, Al-amer, Rasmieh Mustafa, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albakri, Almaza, Aldhaleei, Wafa A, Aldridge, Robert W, Alemohammad, Seyedeh Yasaman, Alemu, Yihun Mulugeta, Al-Gheethi, Adel Ali Saeed, Al-Hanawi, Mohammed Khaled, Ali, Abid, Ali, Amjad, Ali, Iman, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Ali, Victor Ekoche, Ali, Waad, Al-Ibraheem, Akram, Alicandro, Gianfranco, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Alla, François, Almazan, Joseph Uy, Al-Mekhlafi, Hesham M, Alqutaibi, Ahmed 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Published: 2024
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138. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Author: Schumacher, Austin E, Kyu, Hmwe Hmwe, Aali, Amirali, Abbafati, Cristiana, Abbas, Jaffar, Abbasgholizadeh, Rouzbeh, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abd ElHafeez, Samar, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed, Abdollahi, Mohammad, Abdoun, Meriem, Abdullahi, Auwal, Abdurehman, Ame Mehadi, Abebe, Mesfin, Abedi, Aidin, Abedi, Armita, Abegaz, Tadesse M, Abeldaño Zuñiga, Roberto Ariel, Abhilash, E S, Abiodun, Olugbenga Olusola, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Abreu, Lucas Guimarães, Abrha, Woldu Aberhe, Abrigo, Michael R M, Abtahi, Dariush, Abu Rumeileh, Samir, Abu-Rmeileh, Niveen ME, Aburuz, Salahdein, Abu-Zaid, Ahmed, Acuna, Juan Manuel, Adair, Tim, Addo, Isaac Yeboah, Adebayo, Oladimeji M, Adegboye, Oyelola A, Adekanmbi, Victor, Aden, Bashir, Adepoju, Abiola Victor, Adetunji, Charles Oluwaseun, Adeyeoluwa, Temitayo Esther, Adeyomoye, Olorunsola Israel, Adha, Rishan, Adibi, Amin, Adikusuma, Wirawan, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afework, Abel, Afolabi, Aanuoluwapo Adeyimika, Afraz, Ali, Afyouni, Shadi, Afzal, Saira, Agasthi, Pradyumna, Aghamiri, Shahin, Agodi, Antonella, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Muayyad M, Ahmad, Tauseef, Ahmadi, Keivan, Ahmadzade, Amir Mahmoud, Ahmadzade, Mohadese, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Syed Anees, Ajami, Marjan, Aji, Budi, Ajumobi, Olufemi, Akalu, Gizachew Taddesse, Akara, Essona Matatom, Akinosoglou, Karolina, Akkala, Sreelatha, Akyirem, Samuel, Al Hamad, Hanadi, Al Hasan, Syed Mahfuz, Al Homsi, Ammar, Al Qadire, Mohammad, Ala, Moein, Aladelusi, Timothy Olukunle, AL-Ahdal, Tareq Mohammed Ali, Alalalmeh, Samer O, Al-Aly, Ziyad, Alam, Khurshid, Alam, Manjurul, Alam, Zufishan, Al-amer, Rasmieh Mustafa, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albashtawy, Mohammed, AlBataineh, Mohammad T, Aldridge, Robert W, Alemi, Sharifullah, 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Published: 2024
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139. Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Author: Bhattacharjee, Natalia V, Schumacher, Austin E, Aali, Amirali, Abate, Yohannes Habtegiorgis, Abbasgholizadeh, Rouzbeh, Abbasian, Mohammadreza, Abbasi-Kangevari, Mohsen, Abbastabar, Hedayat, Abd ElHafeez, Samar, Abd-Elsalam, Sherief, Abdollahi, Mohammad, Abdollahifar, Mohammad-Amin, Abdoun, Meriem, Abdullahi, Auwal, Abebe, Mesfin, Abebe, Samrawit Shawel, Abiodun, Olumide, Abolhassani, Hassan, Abolmaali, Meysam, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abrha, Woldu Aberhe, Abrigo, Michael R M, Abtahi, Dariush, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abu-Rmeileh, Niveen ME, Adal, Tadele Girum Girum, Adane, Mesafint Molla, Adeagbo, Oluwafemi Atanda Adeagbo, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Aden, Bashir, Adepoju, Abiola Victor, Adetokunboh, Olatunji O, Adetunji, Juliana Bunmi, Adeyinka, Daniel Adedayo, Adeyomoye, Olorunsola Israel, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afolabi, Rotimi Felix, Afyouni, Shadi, Afzal, Muhammad Sohail, Afzal, Saira, Aghamiri, Shahin, Agodi, Antonella, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahlstrom, Austin J, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Muayyad M, Ahmad, Sajjad, Ahmad, Tauseef, Ahmed, Ali, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Meqdad Saleh, Ahmed, Syed Anees, Ajami, Marjan, Aji, Budi, Akalu, Gizachew Taddesse, Akbarialiabad, Hossein, Akinyemi, Rufus Olusola, Akkaif, Mohammed Ahmed, Akkala, Sreelatha, Al Hamad, Hanadi, Al Hasan, Syed Mahfuz, Al Qadire, Mohammad, AL-Ahdal, Tareq Mohammed Ali, Alalalmeh, Samer O, Alalwan, Tariq A, Al-Aly, Ziyad, Alam, Khurshid, Al-amer, Rasmieh Mustafa, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albakri, Almaza, Albashtawy, Mohammed, AlBataineh, Mohammad T, Alemi, Hediyeh, Alemi, Sharifullah, Alemu, Yihun Mulugeta, Al-Eyadhy, Ayman, Al-Gheethi, Adel Ali Saeed, Alhabib, Khalid F, Alhajri, Noora, Alhalaiqa, Fadwa Alhalaiqa Naji, Alhassan, Robert Kaba, Ali, Abid, Ali, Beriwan Abdulqadir, Ali, 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140. Influence of soil - foundation - tank interaction on buckling strength of liquid storage tanks

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141. Mitochondrial Ca2+ Uniporter–Dependent Energetic Dysfunction Drives Hypertrophy in Heart Failure

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142. Shaking table test of a timber building equipped with a novel cost-effective, impact-resilient seismic isolation system

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143. Consequences of the hospital nursing research culture: Perspective of staff nurses

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144. Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author: Steinmetz, Jaimie D, Seeher, Katrin Maria, Schiess, Nicoline, Nichols, Emma, Cao, Bochen, Servili, Chiara, Cavallera, Vanessa, Cousin, Ewerton, Hagins, Hailey, Moberg, Madeline E, Mehlman, Max L, Abate, Yohannes Habtegiorgis, Abbas, Jaffar, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abdelmasseh, Michael, Abdollahi, Mohammad, Abdollahi, Mozhan, Abdollahifar, Mohammad-Amin, Abd-Rabu, Rami, Abdulah, Deldar Morad, Abdullahi, Auwal, Abedi, Aidin, Abedi, Vida, Abeldańo Zuńiga, Roberto Ariel, Abidi, Hassan, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Aboyans, Victor, Abrha, Woldu Aberhe, Abualhasan, Ahmed, Abu-Gharbieh, Eman, Aburuz, Salahdein, Adamu, Lawan Hassan, Addo, Isaac Yeboah, Adebayo, Oladimeji M, Adekanmbi, Victor, Adekiya, Tayo Alex, Adikusuma, Wirawan, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afework, Tsion, Afolabi, Aanuoluwapo Adeyimika, Afraz, Ali, Afzal, Saira, Aghamiri, Shahin, Agodi, Antonella, Agyemang-Duah, 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Shen, Jiabin, Shenoy, Suchitra M, Shetty, Pavanchand H, Shiferaw, Desalegn Shiferaw, Shigematsu, Mika, Shiri, Rahman, Shittu, Aminu, Shivakumar, K M, Shokri, Fereshteh, Shool, Sina, Shorofi, Seyed Afshin, Shrestha, Sunil, Siankam Tankwanchi, Akhenaten Benjamin, Siddig, Emmanuel Edwar, Sigfusdottir, Inga Dora, Silva, João Pedro, Silva, Luís Manuel Lopes Rodrigues, Sinaei, Ehsan, Singh, Balbir Bagicha, Singh, Garima, Singh, Paramdeep, Singh, Surjit, Sirota, Sarah Brooke, Sivakumar, Shravan, Sohag, Abdullah Al Mamun, Solanki, Ranjan, Soleimani, Hamidreza, Solikhah, Solikhah, Solomon, Yerukneh, Solomon, Yonatan, Song, Suhang, Song, Yimeng, Sotoudeh, Houman, Spartalis, Michael, Stark, Benjamin A, Starnes, Joseph R, Starodubova, Antonina V, Stein, Dan J, Steiner, Timothy J, Stovner, Lars Jacob, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sultana, Abida, Sun, Jing, Sunkersing, David, Sunny, Angel, Susianti, Hani, Swain, Chandan Kumar, Szeto, Mindy D, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabai, Shima, Tabish, Mohammad, Taheri, Majid, Tahvildari, Azin, Tajbakhsh, Ardeshir, Tampa, Mircea, Tamuzi, Jacques JL Lukenze, Tan, Ker-Kan, Tang, Haosu, Tareke, Minale, Tarigan, Ingan Ukur, Tat, Nathan Y, Tat, Vivian Y, Tavakoli Oliaee, Razieh, Tavangar, Seyed Mohammad, Tavasol, Arian, Tefera, Yibekal Manaye, Tehrani-Banihashemi, Arash, Temesgen, Worku Animaw, Temsah, Mohamad-Hani, Teramoto, Masayuki, Tesfaye, Amensisa Hailu, Tesfaye, Edosa Geta, Tesler, Riki, Thakali, Ocean, Thangaraju, Pugazhenthan, Thapa, Rajshree, Thapar, Rekha, Thomas, Nikhil Kenny, Thrift, Amanda G, Ticoalu, Jansje Henny Vera, Tillawi, Tala, Toghroli, Razie, Tonelli, Marcello, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Nghia Minh, Tran, Ngoc-Ha, Tran, Phu Van, Tromans, Samuel Joseph, Truelsen, Thomas Clement, Truyen, Thien Tan Tri Tai, Tsatsakis, Aristidis, Tsegay, Guesh Mebrahtom, Tsermpini, Evangelia Eirini, Tualeka, Abdul Rohim, Tufa, Derara Girma, Ubah, Chukwudi 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Barbara, Wilner, Lauren B, Winkler, Andrea Sylvia, Wolfe, Charles D A, Wu, Ai-Min, Wulf Hanson, Sarah, Xu, Suowen, Xu, Xiaoyue, Yadollahpour, Ali, Yaghoubi, Sajad, Yahya, Galal, Yamagishi, Kazumasa, Yang, Lin, Yano, Yuichiro, Yao, Yao, Yehualashet, Sisay Shewasinad, Yeshaneh, Alex, Yesiltepe, Metin, Yi, Siyan, Yiğit, Arzu, Yiğit, Vahit, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa Z, Yu, Chuanhua, Yusuf, Hadiza, Zadey, Siddhesh, Zahedi, Mohammad, Zakham, Fathiah, Zaki, Nazar, Zali, Alireza, Zamagni, Giulia, Zand, Ramin, Zandieh, Ghazal G Z, Zangiabadian, Moein, Zarghami, Amin, Zastrozhin, Mikhail Sergeevich, Zeariya, Mohammed G M, Zegeye, Zelalem Banjaw, Zeukeng, Francis, Zhai, Chunxia, Zhang, Chen, Zhang, Haijun, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhao, Hanqing, Zhao, Yang, Zheng, Peng, Zhou, Hengxing, Zhu, Bin, Zhumagaliuly, Abzal, Zielińska, Magdalena, Zikarg, Yossef Teshome, Zoladl, Mohammad, Murray, Christopher J L, Ong, Kanyin Liane, Feigin, Valery L, Vos, Theo, and Dua, Tarun
Published: 2024
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145. Orchards closer to forest patches produced fewer malformed fruits and more commercial fruits: The importance of legitimate floral visitors

Author: Severiano-Galeana, Fernando, Rosas-Guerrero, Víctor, Alemán-Figueroa, Lorena, Lucas-García, Rodrigo, Almazán-Núñez, R. Carlos, and Kuk-Dzul, José Gabriel
Published: 2024
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146. Environmental sustainability in healthcare: A qualitative study of the perspectives of nursing, medical and public health students in Kazakhstan

Author: Balay-odao, Ejercito Mangawa, Colet, Paolo C., Almazan, Joseph U., Kuntuganova, Anargul, Syzdykova, Alma, Kavashev, Zulyar, Smagulova, Meruyert, Dauletkaliyeva, Zhaniya, Seidakhmetova, Aizat, and Cruz, Jonas Preposi
Published: 2024
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147. Comprehensive analysis of right fascicular and right bundle branch blocks: A multi-center study

Author: Obregón-Rosas, Santiago, García-Almazán, Diego, Flores-Pérez, Cinthia Sofía, Sotelo-Lozano, María Teresa, De Sandoval-Martínez, Edmundo, Hernández-Alcaraz, Fátima Cecilia, López-Mota, Luis Armando, Martínez-Estrada, Manuel Alejandro, Oroz-Domínguez, Aranza Sara, Montañez-Aguirre, Ángel Antonio, Romero-García de Acevedo, Luis Eduardo, Acosta-Castro, Itzayana, Pérez-Rubio Flores, Ricardo, and Ortega-Cerda, José Juan
Published: 2024
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148. HACIA UN ANÁLISIS DE LOS PORTALES WEB DE TURISMO RURAL-INDÍGENA EN MÉXICO: UN ESTUDIO COMPARATIVO DE CASOS

Author: Osorio González, Rebeca, Sandoval-Almazán, Rodrigo, and Purón-Cid, Gabriel
Published: 2023
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149. Boosting background suppression in the NEXT experiment through Richardson-Lucy deconvolution

Author: Simón, A., Ifergan, Y., Redwine, A. B., Weiss-Babai, R., Arazi, L., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arnquist, I. J., Azevedo, C. D. R, Bailey, K., Ballester, F., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Byrnes, N., Cárcel, S., Carrión, J. V., Cebrián, S., Church, E., Conde, C. A. N., Contreras, T., Cossío, F. P., Denisenko, A. A., Díaz, G., Díaz, J., Escada, J., Esteve, R., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F., Freitas, E. D. C., Freixa, Z., Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., González-Díaz, D., Gosh, S., Guenette, R., Gutiérrez, R. M., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero, P., Herrero, V., Ho, J., Jones, B. J. P., Kekic, M., Labarga, L., Laing, A., Lebrun, P., López-March, N., Losada, M., Mano, R. D. P., Martín-Albo, J., Martínez, A., Martínez-Vara, M., Martínez-Lema, G., McDonald, A. D., Meziani, Z. -E., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Vidal, J. Muñoz, Newhouse, C., Novella, P., Nygren, D. R., Oblak, E., Odriozola-Gimeno, M., Palmeiro, B., Para, A., Pérez, J., Querol, M., Renner, J., Ripoll, L., Rivilla, I., García, Y. Rodríguez, Rodríguez, J., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Sorel, M., Stanford, C., Teixeira, J. M. R., Thapa, P., Toledo, J. F., Torrent, J., Usón, A., Veloso, J. F. C. A., Vuong, T. T., Webb, R., White, J. T., Woodruff, K., and Yahlali, N.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Next-generation neutrinoless double beta decay experiments aim for half-life sensitivities of ~$10^{27}$ yr, requiring suppressing backgrounds to <1 count/tonne/yr. For this, any extra background rejection handle, beyond excellent energy resolution and the use of extremely radiopure materials, is of utmost importance. The NEXT experiment exploits differences in the spatial ionization patterns of double beta decay and single-electron events to discriminate signal from background. While the former display two Bragg peak dense ionization regions at the opposite ends of the track, the latter typically have only one such feature. Thus, comparing the energies at the track extremes provides an additional rejection tool. The unique combination of the topology-based background discrimination and excellent energy resolution (1% FWHM at the Q-value of the decay) is the distinguishing feature of NEXT. Previous studies demonstrated a topological background rejection factor of ~5 when reconstructing electron-positron pairs in the $^{208}$Tl 1.6 MeV double escape peak (with Compton events as background), recorded in the NEXT-White demonstrator at the Laboratorio Subterr\'aneo de Canfranc, with 72% signal efficiency. This was recently improved through the use of a deep convolutional neural network to yield a background rejection factor of ~10 with 65% signal efficiency. Here, we present a new reconstruction method, based on the Richardson-Lucy deconvolution algorithm, which allows reversing the blurring induced by electron diffusion and electroluminescence light production in the NEXT TPC. The new method yields highly refined 3D images of reconstructed events, and, as a result, significantly improves the topological background discrimination. When applied to real-data 1.6 MeV $e^-e^+$ pairs, it leads to a background rejection factor of 27 at 57% signal efficiency., Comment: Submitted to JHEP
Published: 2021
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150. Development of a Spectrophotometric Analytical Method to Quantify Ceftriaxone Content in Polymeric Microneedles

Author: Serrano-Castañeda, Pablo, Pérez-Gutiérrez, Diego Alonso, Castillo-Carmona, Luis Fernando, Anguiano-Almazán, Ericka, and Escobar-Chávez, José Juan
Published: 2023
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