Search

Your search keyword '"Ahmed, Hashim U."' showing total 1,106 results
Start Over Author "Ahmed, Hashim U."
1,106 results on '"Ahmed, Hashim U."'

105. PD17-01 DERIVATION AND EXTERNAL VALIDATION OF A RAPID RISK SCORE FOR PREDICTING CLINICALLY SIGNIFICANT PROSTATE CANCER IN MEN WITH AN MRI VISIBLE LESION: A MULTINATIONAL COHORT STUDY

Author

Peters, Max, primary, Eldred-Evans, David, additional, Kurver, Piet, additional, Falagario, Ugo Giovanni, additional, Connor, Martin J., additional, Verhoeff, Joost J.C., additional, Carrieri, Giuseppe, additional, Cormio, Luigi, additional, Taimen, Pekka, additional, Aronen, Hannu J, additional, Knaapila, Juha, additional, Perez, Ileana Montoya, additional, Ettala, Otto, additional, Stabile, Armando, additional, Gandaglia, Giorgio, additional, Fossati, Nicola, additional, Martini, Alberto, additional, Cucchiara, Vito, additional, Briganti, Alberto, additional, Lantz, Anna, additional, Picker, Wolfgang, additional, Haug, Erik, additional, Nordström, Tobias, additional, Tanaka, Mariana Bertoncelli, additional, Hosking-Jervis, Feargus, additional, Reddy, Deepika, additional, Bass, Edward, additional, van Rossum, Peter S.N., additional, Joshi, Suchita, additional, Pegers, Elizabeth, additional, Wong, Kathie, additional, Tam, Henry, additional, Hrouda, David, additional, McCraken, Stuart, additional, Winkler, Mathias, additional, Gordon, Stephen, additional, Qazi, Hasan, additional, Boström, Peter J., additional, Jambor, Ivan, additional, and Ahmed, Hashim U., additional

Published
2022
Full Text
View/download PDF

107. Diagnostic accuracy of magnetic resonance imaging targeted biopsy techniques compared to transrectal ultrasound guided biopsy of the prostate: a systematic review and meta-analysis

Author

Bass, Edward J., Bass, Edward J., Pantović, Ana, Connor, Martin J., Loeb, Stacy, Rastinehad, Ardeshir R., Winkler, Mathias H., Gabe, Rhian, Ahmed, Hashim U., Bass, Edward J., Bass, Edward J., Pantović, Ana, Connor, Martin J., Loeb, Stacy, Rastinehad, Ardeshir R., Winkler, Mathias H., Gabe, Rhian, and Ahmed, Hashim U.

Abstract

Background: Multiparametric MRI localizes cancer in the prostate, allowing for MRI guided biopsy (MRI-GB) 43 alongside transrectal ultrasound-guided systematic biopsy (TRUS-GB). Three MRI-GB approaches exist; visual estimation (COG-TB); fusion software-assisted (FUS-TB) and MRI ‘in-bore’ biopsy (IB-TB). It is unknown whether any of these are superior. We conducted a systematic review and meta-analysis to address three questions. First, whether MRI-GB is superior to TRUS-GB at detecting clinically significant PCa (csPCa). Second, whether MRI-GB is superior to TRUS-GB at avoiding detection of insignificant PCa. Third, whether any MRI-GB strategy is superior at detecting csPCa. Methods: A systematic literature review from 2015 to 2019 was performed in accordance with the START recommendations. Studies reporting PCa detection rates, employing MRI-GB and TRUS-GB were included and evaluated using the QUADAS-2 checklist. 1553 studies were found, of which 43 were included in the meta-analysis. Results: For csPCa, MRI-GB was superior in detection to TRUS-GB (0.83 vs. 0.63 [p = 0.02]). MRI-GB was superior in detection to TRUS-GB at avoiding detection of insignificant PCa. No MRI-GB technique was superior at detecting csPCa (IB-TB 0.87; COG TB 0.81; FUS-TB 0.81, [p = 0.55]). There was significant heterogeneity observed between the included studies. Conclusions: In patients with suspected PCa on MRI, MRI-GB offers superior rates of csPCa detection and reduces detection of insignificant PCa compared to TRUS-GB. No individual MRI-GB technique was found to be better in csPCa detection. Prospective adequately powered randomized controlled trials are required.

Published
2022

108. Cancer Control Outcomes Following Focal Therapy Using High-intensity Focused Ultrasound in 1379 Men with Nonmetastatic Prostate Cancer: A Multi-institute 15-year Experience

Author

Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, Reddy, Deepika, Peters, Max, Shah, Taimur T, van Son, Marieke, Tanaka, Mariana Bertoncelli, Huber, Philipp M, Lomas, Derek, Rakauskas, Arnas, Miah, Saiful, Eldred-Evans, David, Guillaumier, Stephanie, Hosking-Jervis, Feargus, Engle, Ryan, Dudderidge, Tim, Hindley, Richard G, Emara, Amr, Nigam, Raj, McCartan, Neil, Valerio, Massimo, Afzal, Naveed, Lewi, Henry, Orczyk, Clement, Ogden, Chris, Shergill, Iqbal, Persad, Raj, Virdi, Jaspal, Moore, Caroline M, Arya, Manit, Winkler, Mathias, Emberton, Mark, Ahmed, Hashim U, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, Reddy, Deepika, Peters, Max, Shah, Taimur T, van Son, Marieke, Tanaka, Mariana Bertoncelli, Huber, Philipp M, Lomas, Derek, Rakauskas, Arnas, Miah, Saiful, Eldred-Evans, David, Guillaumier, Stephanie, Hosking-Jervis, Feargus, Engle, Ryan, Dudderidge, Tim, Hindley, Richard G, Emara, Amr, Nigam, Raj, McCartan, Neil, Valerio, Massimo, Afzal, Naveed, Lewi, Henry, Orczyk, Clement, Ogden, Chris, Shergill, Iqbal, Persad, Raj, Virdi, Jaspal, Moore, Caroline M, Arya, Manit, Winkler, Mathias, Emberton, Mark, and Ahmed, Hashim U

Published
2022

109. Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging-detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score

Author

Arts-assistenten Radiotherapie, MS Radiotherapie, Cancer, Peters, Max, Eldred-Evans, David, Kurver, Piet, Falagario, Ugo Giovanni, Connor, Martin J, Shah, Taimur T, Verhoeff, Joost J C, Taimen, Pekka, Aronen, Hannu J, Knaapila, Juha, Montoya Perez, Ileana, Ettala, Otto, Stabile, Armando, Gandaglia, Giorgio, Fossati, Nicola, Martini, Alberto, Cucchiara, Vito, Briganti, Alberto, Lantz, Anna, Picker, Wolfgang, Haug, Erik Skaaheim, Nordström, Tobias, Tanaka, Mariana Bertoncelli, Reddy, Deepika, Bass, Edward, van Rossum, Peter S N, Wong, Kathie, Tam, Henry, Winkler, Mathias, Gordon, Stephen, Qazi, Hasan, Boström, Peter J, Jambor, Ivan, Ahmed, Hashim U, Arts-assistenten Radiotherapie, MS Radiotherapie, Cancer, Peters, Max, Eldred-Evans, David, Kurver, Piet, Falagario, Ugo Giovanni, Connor, Martin J, Shah, Taimur T, Verhoeff, Joost J C, Taimen, Pekka, Aronen, Hannu J, Knaapila, Juha, Montoya Perez, Ileana, Ettala, Otto, Stabile, Armando, Gandaglia, Giorgio, Fossati, Nicola, Martini, Alberto, Cucchiara, Vito, Briganti, Alberto, Lantz, Anna, Picker, Wolfgang, Haug, Erik Skaaheim, Nordström, Tobias, Tanaka, Mariana Bertoncelli, Reddy, Deepika, Bass, Edward, van Rossum, Peter S N, Wong, Kathie, Tam, Henry, Winkler, Mathias, Gordon, Stephen, Qazi, Hasan, Boström, Peter J, Jambor, Ivan, and Ahmed, Hashim U

Published
2022

111. The rapid assessment for prostate imaging and diagnosis (RAPID) prostate cancer diagnostic pathway.

Author

Eldred‐Evans, David, Connor, Martin J., Bertoncelli Tanaka, Mariana, Bass, Edward, Reddy, Deepika, Walters, Uma, Stroman, Luke, Espinosa, Easter, Das, Raj, Khosla, Nalin, Tam, Henry, Pegers, Elizabeth, Qazi, Hasan, Gordon, Stephen, Winkler, Mathias, and Ahmed, Hashim U.

Subjects
PROSTATE cancer, PATIENT satisfaction, MAGNETIC resonance imaging, PROSTATE, EARLY detection of cancer
Abstract

Objective: To report outcomes within the Rapid Assessment for Prostate Imaging and Diagnosis (RAPID) diagnostic pathway, introduced to reduce patient and healthcare burdens and standardize delivery of pre‐biopsy multiparametric magnetic resonance imaging (MRI) and transperineal biopsy. Patients and Methods: A total of 2130 patients from three centres who completed the RAPID pathway (3 April 2017 to 31 March 2020) were consecutively entered as a prospective registry. These patients were also compared to a pre‐RAPID cohort of 2435 patients. Patients on the RAPID pathway with an MRI score 4 or 5 and those with PSA density ≥0.12 and an MRI score 3 were advised to undergo a biopsy. Primary outcomes were rates of biopsy and cancer detection. Secondary outcomes included comparison of transperineal biopsy techniques, patient acceptability and changes in time to diagnosis before and after the introduction of RAPID. Results: The median patient age and PSA level were 66 years and 6.6 ng/mL, respectively. Biopsy could be omitted in 43% of patients (920/2130). A further 7.9% of patients (168/2130) declined a recommendation for biopsy. The percentage of biopsies avoided among sites varied (45% vs 36% vs 51%; P < 0.001). In all, 30% (221/742) had a local anaesthetic (grid and stepper) transperineal biopsy. Clinically significant cancer detection (any Gleason score ≥3 + 4) was 26% (560/2130) and detection of Gleason score 3 + 3 alone constituted 5.8% (124/2130); detection of Gleason score 3 + 3 did not significantly vary among sites (P = 0.7). Among participants who received a transperineal targeted biopsy, there was no difference in cancer detection rates among local anaesthetic, sedation and general anaesthetic groups. In the 2435 patients from the pre‐RAPID cohor, time to diagnosis was 32.1 days (95% confidence interval [CI] 29.3–34.9) compared to 15.9 days (95% CI 12.9–34.9) in the RAPID group. A total of 141 consecutive patient satisfaction surveys indicated a high satisfaction rate with the pathway; 50% indicated a preference for having all tests on a single day. Conclusions: The RAPID prostate cancer diagnostic pathway allows 43% of men to avoid a biopsy while preserving good detection of clinically significant cancers and low detection of insignificant cancers, although there were some centre‐level variations. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

116. Effect of Simulation-based Training on Surgical Proficiency and Patient Outcomes: A Randomised Controlled Clinical and Educational Trial

Author

Aydın, Abdullatif, primary, Ahmed, Kamran, additional, Abe, Takashige, additional, Raison, Nicholas, additional, Van Hemelrijck, Mieke, additional, Garmo, Hans, additional, Ahmed, Hashim U., additional, Mukhtar, Furhan, additional, Al-Jabir, Ahmed, additional, Brunckhorst, Oliver, additional, Shinohara, Nobuo, additional, Zhu, Wei, additional, Zeng, Guohua, additional, Sfakianos, John P., additional, Gupta, Mantu, additional, Tewari, Ashutosh, additional, Gözen, Ali Serdar, additional, Rassweiler, Jens, additional, Skolarikos, Andreas, additional, Kunit, Thomas, additional, Knoll, Thomas, additional, Moltzahn, Felix, additional, Thalmann, George N., additional, Lantz Powers, Andrea G., additional, Chew, Ben H., additional, Sarica, Kemal, additional, Shamim Khan, Muhammad, additional, Dasgupta, Prokar, additional, Baig, Umair, additional, Aya, Haleema, additional, Husnain Iqbal, Mohammed, additional, Kum, Francesca, additional, Bultitude, Matthew, additional, Glass, Jonathan, additional, Khan, Azhar, additional, Makanjuola, Jonathan, additional, McCabe, John E., additional, Samsuddin, Azi, additional, McIlhenny, Craig, additional, Brewin, James, additional, Kulkarni, Shashank, additional, Khwaja, Sikandar, additional, Islam, Waliul, additional, Marsh, Howard, additional, Bhat, Taher, additional, Thomas, Benjamin, additional, Cutress, Mark, additional, Housami, Fadi, additional, Nedas, Timothy, additional, Bates, Timothy, additional, Mukherjee, Rono, additional, Graham, Stuart, additional, Bordenave, Matthieu, additional, Coker, Charles, additional, Ahmed, Shwan, additional, Symes, Andrew, additional, Calvert, Robert, additional, Lynch, Ciaran, additional, Long, Ronan, additional, Patterson, Jacob M., additional, Rukin, Nicholas J., additional, Khan, Shahid A., additional, Dasgupta, Ranan, additional, Brown, Stephen, additional, Grey, Ben, additional, Mahmalji, Waseem, additional, Lam, Wayne, additional, Scheitlin, Walter, additional, Saelzler, Norbert, additional, Fiedler, Marcel, additional, Ishikawa, Shuhei, additional, Sasaki, Yoshihiro, additional, Sazawa, Ataru, additional, Shinno, Yuichiro, additional, Mochizuki, Tango, additional, Peter Jessen, Jan, additional, Steiner, Roland, additional, Wendt-Nordahl, Gunnar, additional, Atassi, Nabil, additional, Kohns, Heiko, additional, Cox, Ashley, additional, Rendon, Ricardo, additional, Lawen, Joseph, additional, Bailly, Greg, additional, and Marsh, Trevor, additional

Published
2022
Full Text
View/download PDF

118. Erratum to 'Effect of Simulation-based Training on Surgical Proficiency and Patient Outcomes: A Randomised Controlled Clinical and Educational Trial' [Eur Urol 2022;81:385-393]

Author

Aydın, Abdullatif, Ahmed, Kamran, Abe, Takashige, Raison, Nicholas, Van Hemelrijck, Mieke, Garmo, Hans, Ahmed, Hashim U, Mukhtar, Furhan, Al-Jabir, Ahmed, Brunckhorst, Oliver, Shinohara, Nobuo, Zhu, Wei, Zeng, Guohua, Sfakianos, John P, Gupta, Mantu, Tewari, Ashutosh, Serdar Gözen, Ali, Rassweiler, Jens, Skolarikos, Andreas, Kunit, Thomas, Knoll, Thomas, Moltzahn, Felix, Thalmann, George N, Lantz Powers, Andrea G, Chew, Ben H, Sarica, Kemal, Shamim Khan, Muhammad, and Dasgupta, Prokar

Subjects
610 Medicine & health
Published
2022
Full Text
View/download PDF

119. A systematic review of patients' values, preferences, and expectations for the treatment of metastatic prostate cancer

Author

Connor, Martin J, Genie, Mesfin G, Burns, David, Bass, Edward J, Gonzalez, Michael, Sarwar, Naveed, Falconer, Alison, Mangar, Stephen, Dudderidge, Tim, Khoo, Vincent, Winkler, Mathias, Ahmed, Hashim U, and Watson, Verity

Abstract

Context: advances in systemic agents have increased overall survival for men diagnosed with metastatic prostate cancer. Additional cytoreductive prostate treatments and metastasis-directed therapies are under evaluation. These confer toxicity but may offer incremental survival benefits. Thus, an understanding of patients' values and treatment preferences is important for counselling, decision-making, and guideline development.Objective: to perform a systematic review of patients' values, preferences, and expectations regarding treatment of metastatic prostate cancer.Evidence acquisition: the MEDLINE, Embase, and CINAHL databases were systematically searched for qualitative and preference elucidation studies reporting on patients' preferences for treatment of metastatic prostate cancer. Certainty of evidence was assessed using Grading of Recommendation, Assessment, Development and Evaluation (GRADE) or GRADE Confidence in the Evidence from Reviews of Qualitative Research (CERQual). The protocol was registered on PROSPERO as CRD42020201420.Evidence synthesis: a total of 1491 participants from 15 studies met the prespecified eligibility for inclusion. The study designs included were discrete choice experiments (n = 5), mixed methods (n = 3), and qualitative methods (n = 7). Disease states reported per study were: metastatic castration-resistant prostate cancer in nine studies (60.0%), metastatic hormone-sensitive prostate cancer in two studies (13.3%), and a mixed cohort in four studies (26.6%). In quantitative preference elicitation studies, patients consistently valued treatment effectiveness and delay in time to symptoms as the two top-ranked treatment attributes (low or very low certainty). Patients were willing to trade off treatment-related toxicity for potential oncological benefits (low certainty). In qualitative studies, thematic analysis revealed cancer progression and/or survival, pain, and fatigue as key components in treatment decisions (low or very low certainty). Patients continue to value oncological benefits in making decisions on treatments under qualitative assessment.Conclusions: there is limited understanding of how patients make treatment and trade-off decisions following a diagnosis of metastatic prostate cancer. For appropriate investment in emerging cytoreductive local tumour and metastasis-directed therapies, we should seek to better understand how this cohort weighs the oncological benefits against the risks.Patient summary: We looked at how men with advanced (metastatic) prostate cancer make treatment decisions. We found that little is known about patients' preferences for current and proposed new treatments. Further studies are required to understand how patients make decisions to help guide the integration of new treatments into the standard of care.

Published
2021

121. Diagnostic Accuracy of Abbreviated Bi-Parametric MRI (a-bpMRI) for Prostate Cancer Detection and Screening: A Multi-Reader Study

Author

Brembilla, Giorgio, primary, Giganti, Francesco, additional, Sidhu, Harbir, additional, Imbriaco, Massimo, additional, Mallett, Sue, additional, Stabile, Armando, additional, Freeman, Alex, additional, Ahmed, Hashim U., additional, Moore, Caroline, additional, Emberton, Mark, additional, and Punwani, Shonit, additional

Published
2022
Full Text
View/download PDF

123. Can quantitative analysis of multi-parametric MRI independently predict failure of focal salvage HIFU therapy in men with radio-recurrent prostate cancer?

Author

Rakauskas, Arnas, primary, Shah, Taimur T., additional, Peters, Max, additional, Randeva, Jagpal S., additional, Hosking-Jervis, Feargus, additional, Schmainda, Michael J., additional, Orczyck, Clement, additional, Emberton, Mark, additional, Arya, Manit, additional, Moore, Caroline, additional, and Ahmed, Hashim U., additional

Published
2021
Full Text
View/download PDF

132. MP05-10 IMPACT OF NON-TARGETED PROSTATE SAMPLING HISTOLOGY ON THE PROBABILITY OF RECEIVING INVASIVE LOCAL TREATMENT IN AN MPMRI-TARGETED PATHWAY—ANALYSIS OF 1,719 MEN

Author

Connor, Martin John, primary, van Son, Marieke, additional, Eldred-Evans, David, additional, Bass, Edward J., additional, Tanaka, Mariana Bertoncelli, additional, Walter, Uma, additional, Sakar, Pallab, additional, Hosking-Jervis, Feargus, additional, Bhola-Stewart, Heather, additional, Pegers, Elizabeth, additional, Leelamany, Deepa, additional, Wong, Kathie, additional, Ahmad, Shahzad, additional, McCracken, Stuart, additional, Hrouda, David, additional, Qazi, Hasan, additional, Gordon, Stephen, additional, Winkler, Mathias, additional, and Ahmed, Hashim U., additional

Published
2021
Full Text
View/download PDF

133. PD34-12 MRI FINDINGS IN DE NOVO SYNCHRONOUS METASTATIC PROSTATE CANCER AND IMPLICATIONS FOR CYTOREDUCTIVE SURGERY

Author

Connor, Martin John, primary, Edison, Marie, additional, Bass, Edward J., additional, Eldred-Evans, David, additional, Bertoncelli, Mariana Tanaka, additional, Hrouda, David, additional, Khoubehi, Bijan, additional, Hellawell, Giles, additional, Rai, Bhavan, additional, Dudderidge, Tim, additional, Tam, Henry, additional, Winkler, Mathias, additional, and Ahmed, Hashim U., additional

Published
2021
Full Text
View/download PDF

134. MP01-07 PRESERVATION OF SEXUAL FUNCTION FOLLOWING REZUM® THERAPY FOR LUTS/BPH TOO GOOD TO BE TRUE? REAL WORLD OUTCOMES FROM 181 CASES

Author

Connor, Martin John, primary, Rai, Amar, additional, Khoo, Charlie, additional, Tanaka, Mariana Bertoncelli, additional, Bass, Edward J., additional, Eldred-Evans, David, additional, Agarwal, Sanjiv, additional, Dasgupta, Ranan, additional, Winkler, Mathias, additional, Abboudi, Hamid, additional, El-husseiny, Tamer, additional, and Ahmed, Hashim U., additional

Published
2021
Full Text
View/download PDF

135. MP11-10 RE-REFERRAL RATES IN THE MEDIUM TERM IN PATIENTS WITH A NON-SUSPICIOUS MPMRI WITHIN THE RAPID PATHWAY

Author

Tanaka, Mariana Bertoncelli, primary, Walter, Uma, additional, Eldred-Evans, David, additional, Bass, Edward J., additional, Connor, Martin J., additional, Sarkar, Pallab, additional, Hoskings-Jervis, Feargus, additional, Bhola-Stewart, Heather, additional, Pegers, Elizabeth, additional, Powell, Laura, additional, Leelamany, Deepa, additional, Wong, Kathie, additional, Ahmad, Shahzad, additional, Tam, Henry, additional, Qazi, Hasan, additional, Gordon, Stephen, additional, Hrouda, David, additional, McCracken, Stuart, additional, Winkler, Mathias, additional, and Ahmed, Hashim U., additional

Published
2021
Full Text
View/download PDF

140. B2B: Prostate Cancer

Author

Loeb, Stacy, primary, Black, Peter C., additional, Wyatt, Alexander W., additional, Nyame, Yaw A., additional, Shore, Neal, additional, Tilki, Derya, additional, Castro, Elena, additional, Cooperberg, Matthew, additional, Giri, Veda, additional, Ribal, Maria J., additional, Lughezzani, Giovanni, additional, Sánchez-Salas, Rafael, additional, Moore, Caroline M., additional, Rastinehad, Art, additional, Kerkmeijer, Linda, additional, Ahmed, Hashim U., additional, Akamatsu, Shusuke, additional, de la Taille, Alexandre, additional, Gleave, Martin, additional, and Tanguay, Simon, additional

Published
2021
Full Text
View/download PDF

142. Outcomes of the RAFT trial: robotic surgery after focal therapy

Author

Cathcart, Paul, primary, Ribeiro, Luis, additional, Moore, Caroline, additional, Ahmed, Hashim U., additional, Leslie, Tom, additional, Arya, Manit, additional, Orczyk, Clement, additional, Hindley, Richard G., additional, Cahill, Fidelma, additional, Prendergast, Aaron, additional, Coetzee, Carike, additional, Yogeswaran, Yathushan, additional, Tunna, Kirsty, additional, Sooriakumaran, Prasanna, additional, and Emberton, Mark, additional

Published
2021
Full Text
View/download PDF

143. Effect of Simulation-based Training on Surgical Proficiency and Patient Outcomes: A Randomised Controlled Clinical and Educational Trial

Author

Ayd��n, Abdullatif, Ahmed, Kamran, Abe, Takashige, Raison, Nicholas, Van Hemelrijck, Mieke, Garmo, Hans, Ahmed, Hashim U, Mukhtar, Furhan, Al-Jabir, Ahmed, Brunckhorst, Oliver, Shinohara, Nobuo, Zhu, Wei, Zeng, Guohua, Sfakianos, John P, Gupta, Mantu, Tewari, Ashutosh, G��zen, Ali Serdar, Rassweiler, Jens, Skolarikos, Andreas, Kunit, Thomas, Knoll, Thomas, Moltzahn, Felix, Thalmann, George N., Lantz Powers, Andrea G, Chew, Ben H, Sarica, Kemal, Shamim Khan, Muhammad, and Dasgupta, Prokar

Subjects
610 Medicine & health
Abstract

BACKGROUND It is hypothesised that simulation enhances progression along the initial phase of the surgical learning curve. OBJECTIVE To evaluate whether residents undergoing additional simulation, compared to conventional training, are able to achieve proficiency sooner with better patient outcomes. DESIGN, SETTING, AND PARTICIPANTS This international, multicentre, randomised controlled trial recruited 94 urology residents with experience of zero to ten procedures and no prior exposure to simulation in ureterorenoscopy, selected as an index procedure. INTERVENTION Participants were randomised to simulation or conventional operating room training, as is the current standard globally, and followed for 25 procedures or over 18 mo. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS The number of procedures required to achieve proficiency, defined as achieving a score of ���28 on the Objective Structured Assessment of Technical Skill (OSATS) scale over three consecutive operations, was measured. Surgical complications were evaluated as a key secondary outcome. This trial is registered at www.isrctn.com as ISCRTN 12260261. RESULTS AND LIMITATIONS A total of 1140 cases were performed by 65 participants, with proficiency achieved by 21 simulation and 18 conventional participants over a median of eight and nine procedures, respectively (hazard ratio [HR] 1.41, 95% confidence interval [CI] 0.72-2.75). More participants reached proficiency in the simulation arm in flexible ureterorenoscopy, requiring a lower number of procedures (HR 0.89, 95% CI 0.39-2.02). Significant differences were observed in overall comparison of OSATS scores between the groups (mean difference 1.42, 95% CI 0.91-1.92; p < 0.001), with fewer total complications (15 vs 37; p��=��0.003) and ureteric injuries (3 vs 9; p < 0.001) in the simulation group. CONCLUSIONS Although the number of procedures required to reach proficiency was similar, simulation-based training led to higher overall proficiency scores than for conventional training. Fewer procedures were required to achieve proficiency in the complex form of the index procedure, with fewer serious complications overall. PATIENT SUMMARY This study investigated the effect of simulation training in junior surgeons and found that it may improve performance in real operating settings and reduce surgical complications for complex procedures.

Published
2021
Full Text
View/download PDF

145. Conventional radical versus focal treatment for localised prostate cancer: a propensity score weighted comparison of 6-year tumour control

Author

Cancer, Onderzoek Radiotherapie, Arts-assistenten Radiotherapie, Onderzoek Beeld, Klinische Fysica RT, MS Radiotherapie, van Son, Marieke J., Peters, Max, Reddy, Deepika, Shah, Taimur T., Hosking-Jervis, Feargus, Robinson, Stephen, Lagendijk, Jan J.W., Mangar, Stephen, Dudderidge, Tim, McCracken, Stuart, Hindley, Richard G., Emara, Amr, Nigam, Raj, Persad, Raj, Virdi, Jaspal, Lewi, Henry, Moore, Caroline, Orczyk, Clement, Emberton, Mark, Arya, Manit, Ahmed, Hashim U., van der Voort van Zyp, Jochem R.N., Winkler, Matt, Falconer, Alison, Cancer, Onderzoek Radiotherapie, Arts-assistenten Radiotherapie, Onderzoek Beeld, Klinische Fysica RT, MS Radiotherapie, van Son, Marieke J., Peters, Max, Reddy, Deepika, Shah, Taimur T., Hosking-Jervis, Feargus, Robinson, Stephen, Lagendijk, Jan J.W., Mangar, Stephen, Dudderidge, Tim, McCracken, Stuart, Hindley, Richard G., Emara, Amr, Nigam, Raj, Persad, Raj, Virdi, Jaspal, Lewi, Henry, Moore, Caroline, Orczyk, Clement, Emberton, Mark, Arya, Manit, Ahmed, Hashim U., van der Voort van Zyp, Jochem R.N., Winkler, Matt, and Falconer, Alison

Published
2021

146. Focal therapy compared to radical prostatectomy for non-metastatic prostate cancer: a propensity score-matched study

Author

Arts-assistenten Radiotherapie, Cancer, Onderzoek Radiotherapie, Shah, Taimur T, Reddy, Deepika, Peters, Max, Ball, Daniel, Kim, Na Hyun, Gomez, Enrique Gomez, Miah, Saiful, Evans, David Eldred, Guillaumier, Stephanie, van Rossum, Peter S N, Van Son, Marieke J, Hosking-Jervis, Feargus, Dudderidge, Tim, Hindley, Richard, Emara, Amr, McCracken, Stuart, Greene, Damian, Nigam, Raj, McCartan, Neil, Valerio, Massimo, Minhas, Suks, Afzal, Naveed, Lewi, Henry, Ogden, Chris, Persad, Raj, Virdi, Jaspal, Moore, Caroline M, Arya, Manit, Emberton, Mark, Ahmed, Hashim U, Winkler, Mathias, Arts-assistenten Radiotherapie, Cancer, Onderzoek Radiotherapie, Shah, Taimur T, Reddy, Deepika, Peters, Max, Ball, Daniel, Kim, Na Hyun, Gomez, Enrique Gomez, Miah, Saiful, Evans, David Eldred, Guillaumier, Stephanie, van Rossum, Peter S N, Van Son, Marieke J, Hosking-Jervis, Feargus, Dudderidge, Tim, Hindley, Richard, Emara, Amr, McCracken, Stuart, Greene, Damian, Nigam, Raj, McCartan, Neil, Valerio, Massimo, Minhas, Suks, Afzal, Naveed, Lewi, Henry, Ogden, Chris, Persad, Raj, Virdi, Jaspal, Moore, Caroline M, Arya, Manit, Emberton, Mark, Ahmed, Hashim U, and Winkler, Mathias

Published
2021

147. A Comparison of Prostate Cancer Detection Between Visual-Estimation (Cognitive Registration) and Image-Fusion (Software Registration) Targeted Transperineal Prostate Biopsy

Author

Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, Cancer, Khoo, Christopher C, Eldred-Evans, David, Peters, Max, van Son, Marieke, van Rossum, Peter, Connor, Martin J, Hosking-Jervis, Feargus, Tanaka, Mariana Bertoncelli, Reddy, Deepika, Bass, Edward, Powell, Laura, Ahmad, Shahzad, Pegers, Elizabeth, Joshi, Suchita, Sri, Denosshan, Wong, Kathie, Tam, Henry, Hrouda, David, Qazi, Hasan, Gordon, Stephen, McCracken, Stuart, Winkler, Mathias, Ahmed, Hashim U, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, Cancer, Khoo, Christopher C, Eldred-Evans, David, Peters, Max, van Son, Marieke, van Rossum, Peter, Connor, Martin J, Hosking-Jervis, Feargus, Tanaka, Mariana Bertoncelli, Reddy, Deepika, Bass, Edward, Powell, Laura, Ahmad, Shahzad, Pegers, Elizabeth, Joshi, Suchita, Sri, Denosshan, Wong, Kathie, Tam, Henry, Hrouda, David, Qazi, Hasan, Gordon, Stephen, McCracken, Stuart, Winkler, Mathias, and Ahmed, Hashim U

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results