5,519 results on '"A. Bout"'
Search Results
102. Superior Pedicle Oncoplasty
- Author
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Reyal, Fabien, Laas, Enora, Aubry, Gabrielle, Labrosse, Julie, Bout-Roumazeilles, Apolline, Sabaila, Anne, Rossi, Léa, Feron, Jean-Guillaume, Binder, Jean-Philippe, Couturaud, Benoit, Klimberg, V. Suzanne, editor, Kovacs, Tibor, editor, and Rubio, Isabel T., editor
- Published
- 2020
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103. Deriving Tropical Cyclone-Associated Flood Hazard Information Using Clustered GPM-IMERG Rainfall Signatures: Case Study in Dominica.
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Nabukulu, Catherine, Jetten, Victor G., Ettema, Janneke, van den Bout, Bastian, and Haarsma, Reindert J.
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SMALL states ,RAINFALL ,TROPICAL cyclones ,K-means clustering ,TIME series analysis ,HYDROLOGIC models ,FLOOD warning systems - Abstract
Various stakeholders seek effective methods to communicate the potential impacts of tropical cyclone (TC) rainfall and subsequent flood hazards. While current methods, such as Intensity–Duration–Frequency curves, offer insights, they do not fully capture TC rainfall complexity and variability. This research introduces an innovative workflow utilizing GPM-IMERG satellite precipitation estimates to cluster TC rainfall spatial–temporal patterns, thereby illustrating their potential for flood hazard assessment by simulating associated flood responses. The methodology is tested using rainfall time series from a single TC as it traversed a 500 km diameter buffer zone around Dominica. Spatial partitional clustering with K-means identified the spatial clusters of rainfall time series with similar temporal patterns. The optimal value of K = 4 was most suitable for grouping the rainfall time series of the tested TC. Representative precipitation signals (RPSs) from the quantile analysis generalized the cluster temporal patterns. RPSs served as the rainfall input for the openLISEM, an event-based hydrological model simulating related flood characteristics. The tested TC exhibited three spatially distinct levels of rainfall magnitude, i.e., extreme, intermediate, and least intense, each resulting in different flood responses. Therefore, TC rainfall varies in space and time, affecting local flood hazards; flood assessments should incorporate variability to improve response and recovery. [ABSTRACT FROM AUTHOR]
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- 2024
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104. Evaluation of [ 68 Ga]Ga-DOTA-AeK as a Potential Imaging Tool for PET Imaging of Cell Wall Synthesis in Bacterial Infections.
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Koatale, Palesa C., Welling, Mick M., Mdanda, Sipho, Mdlophane, Amanda, Takyi-Williams, John, Durandt, Chrisna, van den Bout, Iman, Cleeren, Frederik, Sathekge, Mike M., and Ebenhan, Thomas
- Subjects
BACTERIAL cell walls ,POSITRON emission tomography ,ESCHERICHIA coli ,RADIOCHEMICAL purification ,GRAM-negative bacteria - Abstract
The ability of bacteria to recycle exogenous amino acid-based peptides and amino sugars for peptidoglycan biosynthesis was extensively investigated using optical imaging. In particular, fluorescent AeK–NBD was effectively utilized to study the peptidoglycan recycling pathway in Gram-negative bacteria. Based on these promising results, we were inspired to develop the radioactive AeK conjugate [
68 Ga]Ga-DOTA-AeK for the in vivo localization of bacterial infection using PET/CT. An easy-to-implement radiolabeling procedure for DOTA-AeK with [68 Ga]GaCI3 followed by solid-phase purification was successfully established to obtain [68 Ga]Ga-DOTA-AeK with a radiochemical purity of ≥95%. [68 Ga]Ga-DOTA-AeK showed good stability over time with less protein binding under physiological conditions. The bacterial incorporation of [68 Ga]Ga-DOTA-AeK and its fluorescent Aek-NBD analog were investigated in live and heat-killed Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Unfortunately, no conclusive in vitro intracellular uptake of [68 Ga]Ga-DOTA-AeK was observed for E. coli or S. aureus live and heat-killed bacterial strains (p > 0.05). In contrast, AeK-NBD showed significantly higher intracellular incorporation in live bacteria compared to the heat-killed control (p < 0.05). Preliminary biodistribution studies of [68 Ga]Ga-DOTA-AeK in a dual-model of chronic infection and inflammation revealed limited localization at the infection site with non-specific accumulation in response to inflammatory markers. Finally, our study demonstrates proof that the intracellular incorporation of AeK is necessary for successful bacteria-specific imaging using PET/CT. Therefore, Ga-68 was not a suitable radioisotope for tracing the bacterial uptake of AeK tripeptide, as it required chelation with a bulky metal chelator such as DOTA, which may have limited its active membrane transportation. An alternative for optimization is to explore diverse chemical structures of AeK that would allow for radiolabeling with18 F or11 C. [ABSTRACT FROM AUTHOR]- Published
- 2024
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105. An Investigation of Maximal Strength of the Upper Limb Bilaterally in Individuals With Lateral Elbow Tendinopathy: A Systematic Review With Meta-Analysis
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Heales, Luke J., Bout, Nicola, Dines, Brandon, Parker, Tegan, Reddiex, Kent, Kean, Crystal O., and Obst, Steven J.
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Muscle strength -- Health aspects -- Measurement ,Tennis elbow -- Complications and side effects ,Muscle weakness -- Risk factors - Abstract
Objective. The aim of this study was to investigate whether there is evidence of bilateral upper limb strength deficits in individuals with unilateral lateral elbow tendinopathy (LET). Methods. The electronic databases Medline via Ovid, PubMed, and Scopus were searched from inception to March 2020. Included studies encompassed maximal strength outcomes of any upper limb and appendicular musculature in individuals with LET and an asymptomatic comparator. Study quality was rated using a modified version of the Epidemiological Appraisal Instrument. Hedges g effect sizes (ES) and 95% CIs were calculated for comparisons of maximal strength in the LET group and an asymptomatic control group. Meta-analysis using a random-effects model was performed when possible. Results. Fourteen studies were included. Quality appraisal resulted in a mean Epidemiological Appraisal Instrument score of 46% (SD=10%). Meta-analysis revealed strength deficits in shoulder abduction (pooled ES=-0.37 [95% CI=-0.62 to -0.12]) and shoulder external rotation (pooled ES =-0.55 [95% CI =-0.83 to -0.28]) of the symptomatic limb compared with an asymptomatic control group. Meta-analysis also revealed maximal strength deficits in the upper trapezius (pooled ES=-0.26 [95% CI=-0.49 to -0.02]) of the asymptomatic limb compared with an asymptomatic control group. There was also consistent evidence for strength deficits in the serratus anterior, lower trapezius, and wrist extensor muscles and deficits in grip strength of the symptomatic limb as well as strength deficits in the wrist extensor muscles of the asymptomatic limb in individuals with unilateral LET. Conclusion. In individuals with LET, there were maximal strength deficits in shoulder abduction, shoulder external rotation, serratus anterior and lower trapezius muscles, and wrist extension, as well as deficits in grip strength of the symptomatic limb compared with an asymptomatic control group. In addition, there appeared to be strength deficits in the upper trapezius muscle, wrist extension, and metacarpophalangeal joint flexion and extension, as well as deficits in grip strength of the asymptomatic limb in individuals with LET compared with an asymptomatic control group. These results suggest bilateral strength deficits. Impact. These findings highlight the importance of a thorough physical examination and appropriate strengthening intervention for the upper limb with a focus on shoulder and scapular stabilizers, in addition to forearm muscles, in individuals with LET. Lay Summary. In people with tennis elbow, widespread strength deficits, including weakness of the shoulder, forearm, and wrist muscles, may exist. Interestingly, some of these weaknesses appear on both the affected and the unaffected sides in people with tennis elbow. A physical therapist can help strengthen these areas. Keywords: Hand Strength, Muscle Strength, Tennis Elbow, Introduction Lateral elbow tendinopathy (LET) affects the common extensor tendon of the forearm (1-4) and most commonly occurs in the dominant arm of individuals aged between 35 and 54 years [...]
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- 2021
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106. Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration
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van der Bijl, Ivo, Nawaz, Kalim, Kazlauskaite, Ugne, van Stalborch, Anne-Marieke, Tol, Simon, Jimenez Orgaz, Ana, van den Bout, Iman, Reinhard, Nathalie R., Sonnenberg, Arnoud, and Margadant, Coert
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- 2020
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107. Catchment-scale hydrology simulations using inter-variable multi-parameter terrain descriptions
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van den Bout, Bastian and Jetten, Victor
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- 2020
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108. A web-based multi-hazard risk simulation service based on impact chains
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Van Westen, Cees, primary, van den Bout, Bastian, additional, Twayana, Rabina, additional, Pittore, Massimiliano, additional, Dahal, Ashok, additional, Hazarika, Manzul, additional, and Han, Yu, additional
- Published
- 2024
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109. Validation of the Social Functioning Questionnaire "SFQ" in Moroccan Dialectal Arabic
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Yassine, BENHADDOUCH, primary, TOUHAMI, Youssef OUAZZANI HOUSNI, additional, FARES, Nour El Houda, additional, BENMAAMAR, Soumaya, additional, BOUT, Amine, additional, AARAB, Chadya, additional, ELFAKIR, Samira, additional, and AALOUANE, Rachid, additional
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- 2024
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110. Menke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles
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Haghshenas, Sadegheh, primary, Bout, Hidde J., additional, Schijns, Josephine M., additional, Levy, Michael A., additional, Kerkhof, Jennifer, additional, Bhai, Pratibha, additional, McConkey, Haley, additional, Jenkins, Zandra A., additional, Williams, Ella M., additional, Halliday, Benjamin J., additional, Huisman, Sylvia A., additional, Lauffer, Peter, additional, de Waard, Vivian, additional, Witteveen, Laura, additional, Banka, Siddharth, additional, Brady, Angela F., additional, Galazzi, Elena, additional, van Gils, Julien, additional, Hurst, Anna C.E., additional, Kaiser, Frank J., additional, Lacombe, Didier, additional, Martinez-Monseny, Antonio F., additional, Fergelot, Patricia, additional, Monteiro, Fabíola P., additional, Parenti, Ilaria, additional, Persani, Luca, additional, Simarro, Fernando Santos, additional, Simpson, Brittany N., additional, Alders, Mariëlle, additional, Robertson, Stephen P., additional, Sadikovic, Bekim, additional, and Menke, Leonie A., additional
- Published
- 2024
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111. Template-based Approach to Zero-shot Intent Recognition.
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Dmitry Lamanov, Pavel Burnyshev, Ekaterina Artemova, Valentin Malykh, Andrey Bout, and Irina Piontkovskaya
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- 2022
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112. Radiogenic isotopic and clay mineralogical signatures of terrigenous particles as water-mass tracers: New insights into South Atlantic deep circulation during the last termination
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Beny, F., Bout-Roumazeilles, V., Davies, G.R., Waelbroeck, C., Bory, A., Tribovillard, N., Delattre, M., and Abraham, R.
- Published
- 2020
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113. Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis
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Eijkemans, Marianne, Mommers, Monique, Harskamp-van Ginkel, Margreet W., Vrijkotte, Tanja G.M., Ludvigsson, Johnny, Faresjö, Åshild, Bergström, Anna, Ekström, Sandra, Grote, Veit, Koletzko, Berthold, Bønnelykke, Klaus, Eliasen, Anders Ulrik, Bager, Peter, Melbye, Mads, Annesi-Maesano, Isabella, Baïz, Nour, Barros, Henrique, Santos, Ana Cristina, Duijts, Liesbeth, Mensink-Bout, Sara M., Flexeder, Claudia, Koletzko, Sibylle, Schikowski, Tamara, Eggesbø, Merete Åse, Lenters, Virissa, Fernández-Tardón, Guillermo, Subiza-Perez, Mikel, Garcia-Aymerich, Judith, López-Vicente, Mónica, Sunyer, Jordi, Torrent, Maties, Ballester, Ferran, Kelleher, Cecily, Mehegan, John, Berg, Andrea von, Herberth, Gunda, Standl, Marie, Kuehni, Claudia E., Pedersen, Eva S.L., Jansen, Maria, Gehring, Ulrike, Boer, Jolanda M.A., Devereux, Graham, Turner, Steve, Peltola, Ville, Lagström, Hanna, Inskip, Hazel M., Pike, Katharine C., Dalmeijer, Geertje W., Ent, Cornelis K.van der, Thijs, Carel, Eijkemans, Marianne, Mommers, Monique, Harskamp-van Ginkel, Margreet W., Vrijkotte, Tanja G.M., Ludvigsson, Johnny, Faresjö, Åshild, Bergström, Anna, Ekström, Sandra, Grote, Veit, Koletzko, Berthold, Bønnelykke, Klaus, Eliasen, Anders Ulrik, Bager, Peter, Melbye, Mads, Annesi-Maesano, Isabella, Baïz, Nour, Barros, Henrique, Santos, Ana Cristina, Duijts, Liesbeth, Mensink-Bout, Sara M., Flexeder, Claudia, Koletzko, Sibylle, Schikowski, Tamara, Eggesbø, Merete Åse, Lenters, Virissa, Fernández-Tardón, Guillermo, Subiza-Perez, Mikel, Garcia-Aymerich, Judith, López-Vicente, Mónica, Sunyer, Jordi, Torrent, Maties, Ballester, Ferran, Kelleher, Cecily, Mehegan, John, Berg, Andrea von, Herberth, Gunda, Standl, Marie, Kuehni, Claudia E., Pedersen, Eva S.L., Jansen, Maria, Gehring, Ulrike, Boer, Jolanda M.A., Devereux, Graham, Turner, Steve, Peltola, Ville, Lagström, Hanna, Inskip, Hazel M., Pike, Katharine C., Dalmeijer, Geertje W., Ent, Cornelis K.van der, and Thijs, Carel
- Abstract
OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. SETTING: Children aged 0-18 years from 26 European birth cohorts. PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood. MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years. RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results. CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.
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- 2024
114. Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis
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Global Health, Longziekten patientenzorg, Speerpunt Child Health, Child Health, Infection & Immunity, Eijkemans, Marianne, Mommers, Monique, Harskamp-van Ginkel, Margreet W., Vrijkotte, Tanja G.M., Ludvigsson, Johnny, Faresjö, Åshild, Bergström, Anna, Ekström, Sandra, Grote, Veit, Koletzko, Berthold, Bønnelykke, Klaus, Eliasen, Anders Ulrik, Bager, Peter, Melbye, Mads, Annesi-Maesano, Isabella, Baïz, Nour, Barros, Henrique, Santos, Ana Cristina, Duijts, Liesbeth, Mensink-Bout, Sara M., Flexeder, Claudia, Koletzko, Sibylle, Schikowski, Tamara, Eggesbø, Merete Åse, Lenters, Virissa, Fernández-Tardón, Guillermo, Subiza-Perez, Mikel, Garcia-Aymerich, Judith, López-Vicente, Mónica, Sunyer, Jordi, Torrent, Maties, Ballester, Ferran, Kelleher, Cecily, Mehegan, John, Berg, Andrea von, Herberth, Gunda, Standl, Marie, Kuehni, Claudia E., Pedersen, Eva S.L., Jansen, Maria, Gehring, Ulrike, Boer, Jolanda M.A., Devereux, Graham, Turner, Steve, Peltola, Ville, Lagström, Hanna, Inskip, Hazel M., Pike, Katharine C., Dalmeijer, Geertje W., Ent, Cornelis K.van der, Thijs, Carel, Global Health, Longziekten patientenzorg, Speerpunt Child Health, Child Health, Infection & Immunity, Eijkemans, Marianne, Mommers, Monique, Harskamp-van Ginkel, Margreet W., Vrijkotte, Tanja G.M., Ludvigsson, Johnny, Faresjö, Åshild, Bergström, Anna, Ekström, Sandra, Grote, Veit, Koletzko, Berthold, Bønnelykke, Klaus, Eliasen, Anders Ulrik, Bager, Peter, Melbye, Mads, Annesi-Maesano, Isabella, Baïz, Nour, Barros, Henrique, Santos, Ana Cristina, Duijts, Liesbeth, Mensink-Bout, Sara M., Flexeder, Claudia, Koletzko, Sibylle, Schikowski, Tamara, Eggesbø, Merete Åse, Lenters, Virissa, Fernández-Tardón, Guillermo, Subiza-Perez, Mikel, Garcia-Aymerich, Judith, López-Vicente, Mónica, Sunyer, Jordi, Torrent, Maties, Ballester, Ferran, Kelleher, Cecily, Mehegan, John, Berg, Andrea von, Herberth, Gunda, Standl, Marie, Kuehni, Claudia E., Pedersen, Eva S.L., Jansen, Maria, Gehring, Ulrike, Boer, Jolanda M.A., Devereux, Graham, Turner, Steve, Peltola, Ville, Lagström, Hanna, Inskip, Hazel M., Pike, Katharine C., Dalmeijer, Geertje W., Ent, Cornelis K.van der, and Thijs, Carel
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- 2024
115. Development of a Platform for the Generation, Visualisation and Quantification of Disaster Impact Chains
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van Westen, C., Naz, I., van den Bout, B., Flacke, J., Manzella, I., Atun, F., Marr, P., Agmon, G., Ottow, B., Hurlimann, M., Kumar, P., Cocuccioni, S., Schollerer, L., Kulakowska, M., Koelle, B., Ermolieva, T., Twayana, R., van Westen, C., Naz, I., van den Bout, B., Flacke, J., Manzella, I., Atun, F., Marr, P., Agmon, G., Ottow, B., Hurlimann, M., Kumar, P., Cocuccioni, S., Schollerer, L., Kulakowska, M., Koelle, B., Ermolieva, T., and Twayana, R.
- Abstract
There is a lack of publicly available tools for first and second responders and local authorities to evaluate the impact chains of multi-hazard events, with cascading hazards that result in cascading impacts. Within the framework of the EU HORIZON Europe PARATUS project, we are developing an open and online, user-centered methodology and tool for systemic risk assessment, co-designed with stakeholders and addressing physical, socio-economic, and environmental aspects. It will consist of guidelines and lessons learned, links to datasets and tools for multi-hazard risk assessments that consider future scenarios and adaptation measures. We foresee that the PARATUS Platform will have two major blocks: an information service that provides static information (or regularly updated information) and a simulation service, which is a dynamic component where stakeholders can interactively work with the tools in the platform. Based on the analysis of impact chains for historical disaster events we will develop a WIKI with standardized impact chains. These form the basis for the simulation of future events, with particular emphasis on cross-border and cascading impacts. The simulation platform will consists of tools that are dynamic and interactive, and which support the stakeholders to define, analyze and quantify the impact of multi-hazard events, now and under different future scenarios, and to evaluate which risk reduction options would be most suitable.
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- 2024
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116. Physical activity, sedentary behaviour, and childhood asthma:a European collaborative analysis
- Author
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Eijkemans, Marianne, Mommers, Monique, Harskamp-van Ginkel, Margreet W., Vrijkotte, Tanja G.M., Ludvigsson, Johnny, Faresjö, Åshild, Bergström, Anna, Ekström, Sandra, Grote, Veit, Koletzko, Berthold, Bønnelykke, Klaus, Eliasen, Anders Ulrik, Bager, Peter, Melbye, Mads, Annesi-Maesano, Isabella, Baïz, Nour, Barros, Henrique, Santos, Ana Cristina, Duijts, Liesbeth, Mensink-Bout, Sara M., Flexeder, Claudia, Koletzko, Sibylle, Schikowski, Tamara, Eggesbø, Merete Åse, Lenters, Virissa, Fernández-Tardón, Guillermo, Subiza-Perez, Mikel, Garcia-Aymerich, Judith, López-Vicente, Mónica, Sunyer, Jordi, Torrent, Maties, Ballester, Ferran, Kelleher, Cecily, Mehegan, John, Berg, Andrea von, Herberth, Gunda, Standl, Marie, Kuehni, Claudia E., Pedersen, Eva S.L., Jansen, Maria, Gehring, Ulrike, Boer, Jolanda M.A., Devereux, Graham, Turner, Steve, Peltola, Ville, Lagström, Hanna, Inskip, Hazel M., Pike, Katharine C., Dalmeijer, Geertje W., Ent, Cornelis K.van der, Thijs, Carel, Eijkemans, Marianne, Mommers, Monique, Harskamp-van Ginkel, Margreet W., Vrijkotte, Tanja G.M., Ludvigsson, Johnny, Faresjö, Åshild, Bergström, Anna, Ekström, Sandra, Grote, Veit, Koletzko, Berthold, Bønnelykke, Klaus, Eliasen, Anders Ulrik, Bager, Peter, Melbye, Mads, Annesi-Maesano, Isabella, Baïz, Nour, Barros, Henrique, Santos, Ana Cristina, Duijts, Liesbeth, Mensink-Bout, Sara M., Flexeder, Claudia, Koletzko, Sibylle, Schikowski, Tamara, Eggesbø, Merete Åse, Lenters, Virissa, Fernández-Tardón, Guillermo, Subiza-Perez, Mikel, Garcia-Aymerich, Judith, López-Vicente, Mónica, Sunyer, Jordi, Torrent, Maties, Ballester, Ferran, Kelleher, Cecily, Mehegan, John, Berg, Andrea von, Herberth, Gunda, Standl, Marie, Kuehni, Claudia E., Pedersen, Eva S.L., Jansen, Maria, Gehring, Ulrike, Boer, Jolanda M.A., Devereux, Graham, Turner, Steve, Peltola, Ville, Lagström, Hanna, Inskip, Hazel M., Pike, Katharine C., Dalmeijer, Geertje W., Ent, Cornelis K.van der, and Thijs, Carel
- Abstract
OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. SETTING: Children aged 0-18 years from 26 European birth cohorts. PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood. MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years. RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results. CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.
- Published
- 2024
117. Multicentre, randomised controlled trial of physiological-based cord clamping versus immediate cord clamping in infants with a congenital diaphragmatic hernia (PinC):statistical analysis plan
- Author
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Horn-Oudshoorn, Emily J.J., Vermeulen, Marijn J., Knol, Ronny, Bout-Rebel, Rebekka, te Pas, Arjan B., Hooper, Stuart B., Otter, Suzan C.M.Cochius den, Wijnen, Rene M.H., Crossley, Kelly J., Rafat, Neysan, Schaible, Thomas, de Boode, Willem P., Debeer, Anne, Urlesberger, Berndt, Roberts, Calum T., Kipfmueller, Florian, Capolupo, Irma, Burgos, Carmen M., Hansen, Bettina E., Reiss, Irwin K.M., DeKoninck, Philip L.J., Horn-Oudshoorn, Emily J.J., Vermeulen, Marijn J., Knol, Ronny, Bout-Rebel, Rebekka, te Pas, Arjan B., Hooper, Stuart B., Otter, Suzan C.M.Cochius den, Wijnen, Rene M.H., Crossley, Kelly J., Rafat, Neysan, Schaible, Thomas, de Boode, Willem P., Debeer, Anne, Urlesberger, Berndt, Roberts, Calum T., Kipfmueller, Florian, Capolupo, Irma, Burgos, Carmen M., Hansen, Bettina E., Reiss, Irwin K.M., and DeKoninck, Philip L.J.
- Abstract
Background: Infants born with congenital diaphragmatic hernia (CDH) are at high risk of respiratory insufficiency and pulmonary hypertension. Routine practice includes immediate clamping of the umbilical cord and endotracheal intubation. Experimental animal studies suggest that clamping the umbilical cord guided by physiological changes and after the lungs have been aerated, named physiological-based cord clamping (PBCC), could enhance the fetal-to-neonatal transition in CDH. We describe the statistical analysis plan for the clinical trial evaluating the effects of PBCC versus immediate cord clamping on pulmonary hypertension in infants with CDH (PinC trial). Design: The PinC trial is a multicentre, randomised controlled trial in infants with isolated left-sided CDH, born ≥ 35.0 weeks of gestation. The primary outcome is the incidence of pulmonary hypertension in the first 24 h after birth. Maternal outcomes include estimated maternal blood loss. Neonatal secondary outcomes include mortality before discharge, extracorporeal membrane oxygenation therapy, and number of days of mechanical ventilation. Infants are 1:1 randomised to either PBCC or immediate cord clamping using variable random permutated block sizes (4–8), stratified by treatment centre and estimated severity of pulmonary hypoplasia (i.e. mild/moderate/severe). At least 140 infants are needed to detect a relative reduction in pulmonary hypertension by one third, with 80% power and 0.05 significance level. A chi-square test will be used to evaluate the hypothesis that PBCC decreases the occurrence of pulmonary hypertension. This plan is written and submitted without knowledge of the collected data. The trial has been ethically approved.Trial registration:ClinicalTrials.gov NCT04373902 (registered April 2020).
- Published
- 2024
118. Guiding Customs Administrations Towards Successful E-Commerce Import Supervision: Using a Mixed-Method Approach to Identify and Evaluate Supervisory Actions in Preparation of the Reformed Union Customs Code
- Author
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Bout, Kiki (author) and Bout, Kiki (author)
- Abstract
This study examines the challenges faced by the Customs Administration of the Netherlands in supervising cross-border e-commerce imports under the current European customs legislation, the Union Customs Code (UCC). Through a mixed-method approach, including qualitative interviews, document analysis, and simulation modelling, the study identifies potential supervisory actions to strengthen e-commerce import supervision, particularly in anticipation of the proposed UCC reform. The findings indicate the complexities of customs operations and emphasise the need for efficient, fair, and effective enforcement while fostering trust and accountability. The uncertainties surrounding the UCC reform, trade markets, and technological advancements are addressed, with recommendations that focus on strategic automation, stimulating curiosity among customs officers, clear communication, and further research to develop adaptive supervision strategies. These recommendations aim to address core challenges and exploit opportunities for improvement while considering feasibility constraints and potential uncertainties., Engineering and Policy Analysis
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- 2024
119. The Evolution of ISM Mass Probed by Dust Emission -- ALMA Observations at z = 0.3 to 2
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Scoville, N., Aussel, H., Sheth, K., Scott, K. S., Sanders, D., Ivison, R., Pope, A., Capak, P., Bout, P. Vanden, Manohar, S., Kartaltepe, J., and Lilly, S.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The use of submm dust continuum emission to probe the mass of interstellar dust and gas in galaxies is empirically calibrated using samples of local star forming galaxies, Planck observations of the Milky Way and high redshift submm galaxies (SMGs). All of these objects suggest a similar calibration, strongly supporting the view that the Rayleigh-Jeans (RJ) tail of the dust emission can be used as an accurate and very fast probe of the ISM in galaxies. We present ALMA Cycle 0 observations of the Band 7 (350 GHz) dust emission in 107 galaxies from z = 0.2 to 2.5. Three samples of galaxies with a total of 101 galaxies were stellar mass-selected from COSMOS to have $M_* \simeq10^{11}$\msun: 37 at z$\sim0.4$, 33 at z$\sim0.9$ and 31 at z$=2$. A fourth sample with 6 IR luminous galaxies at z = 2 was observed for comparison with the purely mass-selected samples. From the fluxes detected in the stacked images for each sample, we find that the ISM content has decreased a factor $\sim 6$ from $1 - 2 \times 10^{10}$\msun at both z = 2 and 0.9 down to $\sim 2 \times 10^9$\msun at z = 0.4. The IR luminous sample at z = 2 shows a further $\sim 4$ times increase in M$_{ISM}$ compared to the equivalent non-IR bright sample at the same redshift. The gas mass fractions are $\sim 2\pm0.5, 12\pm3, 14\pm2 ~\rm{and} ~53\pm3$ $%$ for the four subsamples (z = 0.4, 0.9, 2 and IR bright galaxies)., Comment: Accepted ApJ 1/13/2014
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- 2014
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120. Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium
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Chen, Ling-Wei, Aubert, Adrien M., Shivappa, Nitin, Bernard, Jonathan Y., Mensink-Bout, Sara M., Geraghty, Aisling A., Mehegan, John, Suderman, Matthew, Polanska, Kinga, Hanke, Wojciech, Jankowska, Agnieszka, Relton, Caroline L., Crozier, Sarah R., Harvey, Nicholas C., Cooper, Cyrus, Hanson, Mark, Godfrey, Keith M., Gaillard, Romy, Duijts, Liesbeth, Heude, Barbara, Hébert, James R., McAuliffe, Fionnuala M., Kelleher, Cecily C., and Phillips, Catherine M.
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- 2021
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121. Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture
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Ellero, Andrea Antonio, van den Bout, Iman, Vlok, Maré, Cromarty, Allan Duncan, and Hurrell, Tracey
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- 2021
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122. COVID-19 related multisystem inflammatory syndrome in children (MIS-C): a case series from a tertiary care pediatric hospital in Qatar
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Hasan, Mohammad Rubayet, Al Zubaidi, Khaled, Diab, Karim, Hejazi, Yahia, Bout-Tabaku, Sharon, Al-Adba, Buthaina, Al Maslamani, Eman, Janahi, Mohammad, Roscoe, Diane, Lopez, Andres Perez, and Tang, Patrick
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- 2021
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123. The University of Texas Millimeter Wave Observatory
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Bout, Paul A. Vanden, Davis, John H., and Loren, Robert B.
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
This is an account of the Millimeter Wave Observatory, a 4.9 meter diameter antenna facility that pioneered continuum observations of planets and interstellar molecular spectroscopy from 1971 to 1988. The circumstances of its founding, development of its instrumentation, and major research contributions are discussed. The MWO role in training of personnel in this new field is illustrated by a listing of student and postdoctoral observers, with titles of PhD theses that included MWO data.
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- 2013
124. Technique de prélèvement d’un lambeau perforant thoracodorsal : mise au point
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Vaucher, R., Dast, S., Bout-Roumazeilles, A., Herlin, C., Bekara, F., and Sinna, R.
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- 2019
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125. Real-world effectiveness and tolerability of switching to doravirine-based antiretroviral therapy in people with HIV: a nationwide, matched, prospective cohort study
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Oomen, Patrick G A, Wit, Ferdinand W N M, Brinkman, Kees, Vrouenraets, Saskia M E, Mudrikova, Tania, van Welzen, Berend J, van der Valk, Marc, van Agtmael, M.A., Bomers, M., Geerlings, S.E., Goorhuis, A., Harris, V.C., Hovius, J.W., Lemkes, B., Nellen, F.J.B., Peters, E.J.G., van der Poll, T., Prins, J.M., Sigaloff, K.C.E., Spoorenberg, V., van Vugt, M., Wiersinga, W.J., Bruins, C., van Eden, J., Hylkema-van den Bout, I.J., Laan, L.M., Pijnappel, F.J.J., Smalhout, S.Y., Spelbrink, M.E., Weijsenfeld, A.M., Back, N.K.T., Cornelissen, M.T.E., van Houdt, R., Jonges, M., Jurriaans, S., Schinkel, C.J., Welkers, M.R.A., Wolthers, K.C., van den Berge, M., Stegeman, A., Baas, S., Hage de Looff, L., van Arkel, A., Stohr, J., Wintermans, B., Pronk, M.J.H., Ammerlaan, H.S.M., de Bree, C., de Munnik, E.S., Phaf, S., Deiman, B., Jansz, A.R., Scharnhorst, V., Tjhie, J., Wegdam, M.C.A., Nellen, J., van Eeden, A., Hoornenborg, E., de Stoppelaar, S., Alers, W., Elsenburg, L.J.M., Nobel, H., Schinkel, C.J., van Kasteren, M.E.E., Berrevoets, M.A.H., Brouwer, A.E., de Kruijf-van de Wiel, B.A.F.M., Adams, A., Pawels-van Rijkevoorsel, M., Murck, J.L., Rokx, C., Anas, A.A., Bax, H.I., van Gorp, E.C.M., de Mendonça Melo, M., van Nood, E., Nouwen, J.L., Rijnders, B.J.A., Schurink, C.A.M., Slobbe, L., de Vries-Sluijs, T.E.M.S., Bassant, N., van Beek, J.E.A., Vriesde, M., van Zonneveld, L.M., de Groot, J., van Kampen, J.J.A., Koopmans, M.P.G., Rahamat-Langendoen, J.C., Branger, J., Douma, R.A., Cents-Bosma, A.S., Mulder, M.A., Schippers, E.F., van Nieuwkoop, C., Geilings, J., van de Ven, E., van der Hut, G., van Burgel, N.D., Leyten, E.M.S., Gelinck, L.B.S., Mollema, F., Langbein, M., Wildenbeest, G.S., Nguyen, T., Groeneveld, P.H.P., Bouwhuis, J.W., Lammers, A.J.J., van Hulzen, A.G.W., Kraan, S., Kruiper, M.S.M., Debast, S.B., Wagenvoort, G.H.J., Roukens, A.H.E., de Boer, M.G.J., Jolink, H., Lambregts, M.M.C., Scheper, H., van Holten, N., van der Sluis, D., Claas, E.C.J., Wessels, E., den Hollander, J.G., El Moussaoui, R., Pogany, K., Brouwer, C.J., Heida-Peters, D., Mulder, E., Smit, J.V., Struik-Kalkman, D., van Niekerk, T., Pontesilli, O., van Tienen, C., Lowe, S.H., Oude Lashof, A.M.L., Posthouwer, D., Stoop, A., van Wolfswinkel, M.E., Ackens, R.P., Elasri, M., Houben-Pintaric, K., Schippers, J., Havenith, T.R.A., van Loo, M., van Vonderen, M.G.A., Kampschreur, L.M., Timmer, C., van Broekhuizen, M.C., Faber, S., Al Moujahid, A., Kootstra, G.J., Delsing, C.E., van der Burg-van de Plas, M., Scheiberlich, L., Kortmann, W., van Twillert, G., Renckens, R., Wagenaar, J., Ruiter-Pronk, D., Stander, B., Cohen Stuart, J.W.T., Hoogewerf, M., Rozemeijer, W., Sinnige, J.C., Brinkman, K., van den Berk, G.E.L., Lettinga, K.D., de Regt, M., Schouten, W.E.M., Stalenhoef, J.E., Blaauw, H., Geerders, G.F., Kleene, M.J., Knapen, M., Kok, M., van der Meché, I.B., Toonen, A.J.M., Wijnands, S., Wttewaal, E., Kwa, D., van de Laar, T.J.W., van Crevel, R., van Aerde, K., Dofferhoff, A.S.M., Henriet, S.S.V., ter Hofstede, H.J.M., Hoogerwerf, J., Richel, O., Albers, M., Grintjes-Huisman, K.J.T., de Haan, M., Marneef, M., McCall, M., Rahamat-Langendoen, J., Ruizendaal, E., Burger, D., Gisolf, E.H., Claassen, M., Hassing, R.J., ter Beest, G., van Bentum, P.H.M., Neijland, Y., Valette, M., Swanink, C.M.A., Klein Velderman, M., van Lelyveld, S.F.L., Soetekouw, R., van der Prijt, L.M.M., van der Swaluw, J., Kalpoe, J.S., Wagemakers, A., Vahidnia, A., Lauw, F.N., Verhagen, D.W.M., van Wijk, M., Bierman, W.F.W., Bakker, M., van Bentum, R.A., van den Boomgaard, M.A., Kleinnijenhuis, J., Kloeze, E., Middel, A., Postma, D.F., Schenk, H.M., Stienstra, Y., Wouthuyzen-Bakker, M., Boonstra, A., Maerman, M.M.M., de Weerd, D.A., van Eije, K.J., Knoester, M., van Leer-Buter, C.C., Niesters, H.G.M., Barth, R.E., Bruns, A.H.W., Ellerbroek, P.M., Hensgens, M.P.M., Oosterheert, J.J., Schadd, E.M., Verbon, A., Griffioen-van Santen, B.M.G., de Kroon, I., Schuurman, R., Verduyn Lunel, F.M., Wensing, A.M.J., van der Valk, M., Zaheri, S., Boyd, A.C., Bezemer, D.O., Jongen, V.W., van Sighem, A.I., Smit, C., Wit, F.W.M.N., Hillebregt, M.M.J., Woudstra, T.J., Rutkens, T., Bergsma, D., Brétin, N.M., Koster, L.E., Lelivelt, K.J., van de Sande, L., Schoorl, M.J.C., Visser, K.M., van der Vliet, S.T., Paling, F., van den Akker, M., Akpomukai, O.M., Alexander, R., Bakker, Y.M., Bastos Sales, L., El Berkaoui, A., Bezemer-Goedhart, M., Djoechro, E.A., Grolleman, J.M., El Hammoud, I., Khouw, M.R., Lodewijk, C.R.E., Lucas, E.G.A., van Meerveld-Derks, S., Mulder, H.W., Munjishvili, L., Ree, C.M.J., Regtop, R., van Rijk, A.F., Ruijs-Tiggelman, Y.M.C., Schnörr, P.P., van Veen, R., van Vliet-Klein Gunnewiek, W.H.G., and Witte, E.C.M.
- Abstract
Currently, real-world data on doravirine are scarce. In a national prospective cohort, we assessed the effectiveness and tolerability of switching to doravirine-based antiretroviral therapy (ART) in people with HIV.
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- 2024
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126. CO(1-0) in z>2 Quasar Host Galaxies: No Evidence for Extended Molecular Gas Reservoirs
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Riechers, Dominik A., Carilli, Christopher L., Maddalena, Ronald J., Hodge, Jacqueline, Harris, Andrew I., Baker, Andrew J., Walter, Fabian, Wagg, Jeff, Bout, Paul A. Vanden, Weiss, Axel, and Sharon, Chelsea E.
- Subjects
Astrophysics - Cosmology and Extragalactic Astrophysics - Abstract
We report the detection of CO(1-0) emission in the strongly lensed high-redshift quasars IRAS F10214+4724 (z=2.286), the Cloverleaf (z=2.558), RX J0911+0551 (z=2.796), SMM J04135+10277 (z=2.846), and MG 0751+2716 (z=3.200), using the Expanded Very Large Array and the Green Bank Telescope. We report lensing-corrected CO(1-0) line luminosities of L'(CO) = 0.34-18.4 x 10^10 K km/s pc^2 and total molecular gas masses of M(H2) = 0.27-14.7 x 10^10 Msun for the sources in our sample. Based on CO line ratios relative to previously reported observations in J>=3 rotational transitions and line excitation modeling, we find that the CO(1-0) line strengths in our targets are consistent with single, highly-excited gas components with constant brightness temperature up to mid-J levels. We thus do not find any evidence for luminous extended, low excitation, low surface brightness molecular gas components. These properties are comparable to those found in z>4 quasars with existing CO(1-0) observations. These findings stand in contrast to recent CO(1-0) observations of z~2-4 submillimeter galaxies (SMGs), which have lower CO excitation and show evidence for multiple excitation components, including some low-excitation gas. These findings are consistent with the picture that gas-rich quasars and SMGs represent different stages in the early evolution of massive galaxies., Comment: 6 pages, 4 figures, 1 table, to appear in ApJL (EVLA Special Issue; accepted June 10, 2011)
- Published
- 2011
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127. Enhanced Dense Gas Fraction in Ultra-Luminous Infrared Galaxies
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Juneau, S., Narayanan, D. T., Moustakas, J., Shirley, Y. L., Bussmann, R. S., Kennicutt Jr, R. C., and Bout, P. A. Vanden
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Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We present a detailed analysis of the relation between infrared luminosity and molecular line luminosity, for a variety of molecular transitions, using a sample of 34 nearby galaxies spanning a broad range of infrared luminosities (10^{10} < L_{IR} < 10^{12.5} L_sun). We show that the power-law index of the relation is sensitive to the critical density of the molecular gas tracer used, and that the dominant driver in observed molecular line ratios in galaxies is the gas density. As most nearby ultraluminous infrared galaxies (ULIRGs) exhibit strong signatures of active galactic nuclei (AGN) in their center, we revisit previous claims questioning the reliability of HCN as a probe of the dense gas responsible for star formation in the presence of AGN. We find that the enhanced HCN(1-0)/CO(1-0) luminosity ratio observed in ULIRGs can be successfully reproduced using numerical models with fixed chemical abundances and without AGN-induced chemistry effects. We extend this analysis to a total of ten molecular line ratios by combining the following transitions: CO(1-0), HCO+(1-0), HCO+(3-2), HCN(1-0), and HCN(3-2). Our results suggest that AGNs reside in systems with higher dense gas fraction, and that chemistry or other effects associated with their hard radiation field may not dominate (NGC 1068 is one exception). Galaxy merger could be the underlying cause of increased dense gas fraction and the evolutionary stage of such mergers may be another determinant of the HCN/CO luminosity ratio., Comment: 20 pages, 10 figures. Published in The Astrophysical Journal (ApJ 707, 1217). Fixed a reference
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- 2009
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128. Continuum Observations at 350 Microns of High-Redshift Molecular Emission Line Galaxies
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Wu, Jingwen, Bout, Paul Vanden, Evans, Neal, and Dunham, Michael
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We report observations of 15 high redshift (z = 1-5) galaxies at 350 microns using the Caltech Submillimeter Observatory and SHARC-II array detector. Emission was detected from eight galaxies, for which far-infrared luminosities, star formation rates, total dust masses, and minimum source size estimates are derived. These galaxies have star formation rates and star formation efficiencies comparable to other high redshift molecular emission line galaxies. The results are used to test the idea that star formation in these galaxies occurs in a large number of basic units, the units being similar to star-forming clumps in the Milky Way. The luminosity of these extreme galaxies can be reproduced in a simple model with (0.9-30) *10^6 dense clumps, each with a luminosity of 5 *10^5 Lsun, the mean value for such clumps in the Milky Way. Radiative transfer models of such clumps can provide reasonable matches to the overall SEDs of the galaxies. They indicate that the individual clumps are quite opaque in the far-infrared. Luminosity to mass ratios vary over two orders of magnitude, correlating strongly with the dust temperature derived from simple fits to the SED. The gas masses derived from the dust modeling are in remarkable agreement with those from CO luminosities, suggesting that the assumptions going into both calculations are reasonable., Comment: 17 pages, 8 figures. Accepted by ApJ
- Published
- 2009
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129. Exponentially cascaded cross-sectional volume estimates from elevation data
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Van den Bout, Bastian, primary and Glas, Vera, additional
- Published
- 2024
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130. Exploring the metabolic potential ofAeromonasto utilise the carbohydrate polymer chitin
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Tugui, Claudia G., primary, Sorokin, Dimitry Y., additional, Hijnen, Wim, additional, Wunderer, Julia, additional, Bout, Kaatje, additional, van Loosdrecht, Mark C.M., additional, and Pabst, Martin, additional
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- 2024
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131. Magnesium intake, bone mineral density, and fractures: results from the Women’s Health Initiative Observational Study 1 , 2 , 3 , 4
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Orchard, Tonya S, Larson, Joseph C, Alghothani, Nora, Bout-Tabaku, Sharon, Cauley, Jane A, Chen, Zhao, LaCroix, Andrea Z, Wactawski-Wende, Jean, and Jackson, Rebecca D
- Subjects
Reproductive Medicine ,Biomedical and Clinical Sciences ,Clinical Sciences ,Nutrition and Dietetics ,Osteoporosis ,Clinical Research ,Aging ,Prevention ,Musculoskeletal ,Aged ,Bone Density ,Bone and Bones ,Cohort Studies ,Diet ,Dietary Supplements ,Female ,Hip Fractures ,Humans ,Incidence ,Magnesium ,Magnesium Deficiency ,Medical Records ,Middle Aged ,Osteoporosis ,Postmenopausal ,Osteoporotic Fractures ,Risk Factors ,Surveys and Questionnaires ,United States ,Wrist ,Engineering ,Medical and Health Sciences ,Nutrition & Dietetics ,Clinical sciences ,Nutrition and dietetics - Abstract
BackgroundMagnesium is a necessary component of bone, but its relation to osteoporotic fractures is unclear.ObjectiveWe examined magnesium intake as a risk factor for osteoporotic fractures and altered bone mineral density (BMD).DesignThis prospective cohort study included 73,684 postmenopausal women enrolled in the Women's Health Initiative Observational Study. Total daily magnesium intake was estimated from baseline food-frequency questionnaires plus supplements. Hip fractures were confirmed by a medical record review; other fractures were identified by self-report. A baseline BMD analysis was performed in 4778 participants.ResultsBaseline hip BMD was 3% higher (P < 0.001), and whole-body BMD was 2% higher (P < 0.001), in women who consumed >422.5 compared with
- Published
- 2014
132. Le portfolio de l’interne de chirurgie plastique : un outil d’aide à la formation des internes de chirurgie plastique en France ?
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Bout-Roumazeilles, A., Dast, S., Assaf, N., Herlin, C., and Sinna, R.
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- 2019
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133. Haematological immune-related adverse events induced by anti-PD-1 or anti-PD-L1 immunotherapy: a descriptive observational study
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Delanoy, Nicolas, Michot, Jean-Marie, Comont, Thibault, Kramkimel, Nora, Lazarovici, Julien, Dupont, Romain, Champiat, Stéphane, Chahine, Claude, Robert, Caroline, Herbaux, Charles, Besse, Benjamin, Guillemin, Aude, Mateus, Christine, Pautier, Patricia, Saïag, Philippe, Madonna, Emanuela, Maerevoet, Marie, Bout, Jean-Christophe, Leduc, Charlotte, Biscay, Pascal, Quere, Gilles, Nardin, Charlée, Ebbo, Mikael, Albigès, Laurence, Marret, Grégoire, Levrat, Virginie, Dujon, Cécile, Vargaftig, Jacques, Laghouati, Salim, Croisille, Laure, Voisin, Anne-Laure, Godeau, Bertrand, Massard, Christophe, Ribrag, Vincent, Marabelle, Aurélien, Michel, Marc, and Lambotte, Olivier
- Published
- 2019
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134. Les troubles anxio-dépressifs chez des patients porteurs du virus de l’hépatite C au moment de la cure par interféron : une étude longitudinale
- Author
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Bout, Amine, Aarab, Chadya, Ayoubi, Khadija, Aalouane, Rachid, and Rammouz, Ismail
- Published
- 2019
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135. Nieuwe regels voor de gesloten jeugdhulp versterken de rechtspositie van jeugdigen
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van den Heuvel, J.K., primary and van den Bout, L., additional
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- 2023
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136. The Star Formation Rate - Dense Gas Relation in Galaxies as Measured by HCN (3-2) Emission
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Bussmann, R. S., Narayanan, D., Shirley, Y. L., Juneau, S., Wu, J., Solomon, P. M., Bout, P. A. Vanden, Moustakas, J., and Walker, C. K.
- Subjects
Astrophysics - Abstract
We present observations made with the 10m Heinrich Hertz Sub-Millimeter Telescope of HCN (3-2) emission from a sample of 30 nearby galaxies ranging in infrared luminosity from 10^10 - 10^12.5 L_sun and HCN (3-2) luminosity from 10^6 - 10^9 K km s^-1 pc^2. We examine the correlation between the infrared luminosity and HCN (3-2) luminosity and find that the best fit linear regression has a slope (in log-log space) of 0.74+/-0.12. Including recently published data from Gracia-Carpio et al. tightens the constraints on the best-fit slope to 0.79+/-0.09. This slope below unity suggests that the HCN (3-2) molecular line luminosity is not linearly tracing the amount of dense gas. Our results are consistent with predictions from recent theoretical models that find slopes below unity when the line luminosity depends upon the average gas density with a power-law index greater than a Kennicutt-Schmidt index of 1.5., Comment: 4 pages, 1 table, 2 figures; accepted to the ApJL
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- 2008
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137. Total control over ultracold interactions via electric and magnetic fields
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Marcelis, Bout, Verhaar, Boudewijn, and Kokkelmans, Servaas
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Physics - Atomic Physics ,Condensed Matter - Other Condensed Matter - Abstract
The scattering length is commonly used to characterize the strength of ultracold atomic interactions, since it is the leading parameter in the low-energy expansion of the scattering phase shift. Its value can be modified via a magnetic field, by using a Feshbach resonance. However, the effective range term, which is the second parameter in the phase shift expansion, determines the width of the resonance and gives rise to important properties of ultracold gases. Independent control over this parameter is not possible by using a magnetic field only. We demonstrate that a combination of magnetic and electric fields can be used to get independent control over both parameters, which leads to full control over elastic ultracold interactions., Comment: 4 pages, 3 figures
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- 2007
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138. VLA Limits for Intermediate Mass Black Holes in Three Globular Clusters
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Bash, F. N., Gebhardt, K., Goss, W. M., and Bout, P. A. Vanden
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Astrophysics - Abstract
The observational evidence for central black holes in globular clusters has been argued extensively, and their existence has important consequences for both the formation and evolution of the cluster. Most of the evidence comes from dynamical arguments, but the interpretation is difficult, given the short relaxation times and old ages of the clusters. One of the most robust signatures for the existence of a black hole is radio and/or X-ray emission. We observed three globular clusters, NGC6093 (M80), NGC6266 (M62), and NGC7078 (M15), with the VLA in the A and C configuration with a 3-sigma noise of 36, 36 and 25 microJy, respectively. We find no statistically-significant evidence for radio emission from the central region for any of the three clusters. NGC6266 shows a 2-sigma detection. It is difficult to infer a mass from these upper limits due to uncertainty about the central gas density, accretion rate, and accretion model., Comment: 5 pages, accepted for publication in the Astronomical Journal
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- 2007
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139. HCN Observations of Dense Star-Forming Gas in High Redshift Galaxies
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Gao, Yu, Carilli, Chris L., Solomon, Philip M., and Bout, Paul A. Vanden
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Astrophysics - Abstract
We present here the sensitive HCN(1-0) observations made with the VLA of two submillimeter galaxies and two QSOs at high-redshift. HCN emission is the signature of dense molecular gas found in GMC cores, the actual sites of massive star formation. We have made the first detection of HCN in a submillimeter galaxy, SMM J16359+6612. The HCN emission is seen with a signal to noise ratio of 4$\sigma$ and appears to be resolved as a double-source of $\approxlt 2''$ separation. Our new HCN observations, combined with previous HCN detections and upper limits, show that the FIR/HCN ratios in these high redshift sources lie systematically above the FIR/HCN correlation established for nearby galaxies by about a factor of 2. Even considering the scatter in the data and the presence of upper limits, this is an indication that the FIR/HCN ratios for the early Universe molecular emission line galaxies (EMGs) deviate from the correlation that fits Galactic giant molecular cloud cores, normal spirals, LIRGs, and ULIRGs. This indicates that the star formation rate per solar mass of dense molecular gas is higher in the high-$z$ objects than in local galaxies including normal spirals LIRGs and ULIRGs. The limited HCN detections at high-redshift show that the HCN/CO ratios for the high-$z$ objects are high and are comparable to those of the local ULIRGs rather than those of normal spirals. This indicates that EMGs have a high fraction of dense molecular gas compared to total molecular gas traced by CO emission., Comment: 14 pages including 4 figures; ApJL accepted
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- 2007
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140. Detection of HNC and tentative detection of CN at z=3.9
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Guelin, M., Salome, P., Neri, R., Garcia-Burillo, S., Gracia-Carpio, J., Cernicharo, J., Cox, P., Planesas, P., Solomon, P. M., Tacconi, L. J., and Bout, P. Vanden
- Subjects
Astrophysics - Abstract
Molecular line emission from high-redshift galaxies holds great promise for the study of galaxy formation and evolution. The weak signals can only be detected with the largest mm-wave telescopes, such as the IRAM interferometer. We report the detection of the J = 5-4 line of HNC and the tentative detection of the N= 4-3 line of CN in the quasar APM08279+5255 at z=3.9. These are the 4th and 5th molecular species detected at such a high redshift. The derived HNC and CN line intensities are 0.6 and 0.4 times that of HCN J= 5-4. If HNC and HCN are co-spatial and if their J= 5-4 lines are collisionally excited, the [HNC]/[HCN] abundance ratio must be equal to 0.6 within a factor of 2, similar to its value in the cold Galactic clouds and much larger than in the hot molecular gas associated with Galactic HII regions. It is possible, however, that fluorescent infrared radiation plays an important role in the excitation of HNC and HCN., Comment: Accepted for publication in Astronomy and Astrophysics Letters (A&ALetters), acceptance date = 7th December 2006; 4 pages, 2 figures
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- 2006
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141. A New Probe of Dense Gas at High Redshift: Detection of HCO+(5-4) Line Emission in APM 08279+5255
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Garcia-Burillo, S., Gracia-Carpio, J., Guelin, M., Neri, R., Cox, P., Planesas, P., Solomon, P. M., Tacconi, L. J., and Bout, P. A. Vanden
- Subjects
Astrophysics - Abstract
We report the detection of HCO+(5-4) emission from the Broad Absorption Line (BAL) quasar APM08279+5255 at z=3.911 based on observations conducted at the IRAM Plateau de Bure interferometer. This represents the first detection of this molecular ion at such a high redshift. The inferred line luminosity, uncorrected for lensing, is L'(HCO+)=(3.5+-0.6)x10^10 Kkms^-1pc^2. The HCO+ J=5-4 source position coincides within the errors with that reported from previous HCN J=5-4 and high-J CO line observations of this quasar. The HCO+ line profile central velocity and width are consistent with those derived from HCN. This result suggests that HCO+(5-4) emission comes roughly from the same circumnuclear region probed by HCN. However, the HCN(5-4)/HCO+(5-4) intensity ratio measured in APM08279+5255 is significantly larger than that predicted by simple radiative transfer models, which assume collisional excitation and equal molecular abundances. This could imply that the [HCN]/[HCO^+] abundance ratio is particularly large in this source, or that the J=5 rotational levels are predominantly excited by IR fluorescent radiation., Comment: Accepted for publication in ApJ Letters, May 25
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- 2006
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142. Fermionic superfluidity with positive scattering length
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Marcelis, Bout and Kokkelmans, Servaas
- Subjects
Condensed Matter - Statistical Mechanics ,Condensed Matter - Superconductivity - Abstract
Superfluidity in an ultracold Fermi gas is usually associated with either a negative scattering length, or the presence of a two-body bound state. We show that none of these ingredients is necessary to achieve superfluidity. Using a narrow Feshbach resonance with strong repulsive background interactions, the effective interactions can be repulsive for small energies and attractive for energies around the Fermi energy, similar to the effective interactions between electrons in a metallic superconductor. This can result in BCS-type superfluidity while the scattering length is positive., Comment: 6 pages, 3 figures; v2: added references and details energy-dependent interaction
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- 2005
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143. The Black Hole - Bulge Relationship for QSOs at High Redshift
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Shields, G. A., Menezes, K. L., Massart, C. A., and Bout, P. Vanden
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Astrophysics - Abstract
We examine the black hole mass - galaxy bulge relationship in high-redshift QSOs. Black hole masses are derived from the broad emission lines, and the host galaxy stellar velocity dispersion sigma is estimated from the widths of the radio CO emission lines. At redshifts z > 3, the CO line widths are narrower than expected for the black hole mass, indicating that these giant black holes reside in undersized bulges by an order of magnitude or more. The largest black holes (above 10^9 solar masses) evidently grow rapidly in the early universe without commensurate growth of their host galaxies. CO line widths offer a unique opportunity to study AGN host galaxy dynamics at high redshift., Comment: 16 pages, 4 EPS figures, accepted for publication in The Astrophysical Journal
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- 2005
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144. Connecting Dense Gas Tracers of Star Formation in our Galaxy to High-z Star Formation
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Wu, Jingwen, Evans II, Neal J., Gao, Yu, Solomon, Philip M., Shirley, Yancy L., and Bout, Paul A. Vanden
- Subjects
Astrophysics - Abstract
Observations have revealed prodigious amounts of star formation in starburst galaxies as traced by dust and molecular emission, even at large redshifts. Recent work shows that for both nearby spiral galaxies and distant starbursts, the global star formation rate, as indicated by the infrared luminosity, has a tight and almost linear correlation with the amount of dense gas as traced by the luminosity of HCN. Our surveys of Galactic dense cores in HCN 1-0 emission show that this correlation continues to a much smaller scale, with nearly the same ratio of infrared luminosity to HCN luminosity found over 7-8 orders of magnitude in L_IR, with a lower cutoff around 10^{4.5} L_sun of infrared luminosity. The linear correlation suggests that we may understand distant star formation in terms of the known properties of local star-forming regions. Both the correlation and the luminosity cutoff can be explained if the basic unit of star formation in galaxies is a dense core, similar to those studied in our Galaxy., Comment: 10 pages, 2 figures. In press for ApJ Letters
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- 2005
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145. Molecular Gas at High Redshift
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Solomon, P. M. and Bout, P. A. Vanden
- Subjects
Astrophysics - Abstract
The Early Universe Molecular Emission Line Galaxies (EMGs) are a population of galaxies with only 36 examples that hold great promise for the study of galaxy formation and evolution at high redshift. The classification, luminosity of molecular line emission, molecular mass, far-infrared (FIR) luminosity, star formation efficiency, morphology, and dynamical mass of the currently known sample are presented and discussed. The star formation rates derived from the FIR luminosity range from about 300 to 5000 M(sun)per year and the molecular mass from 4 x 10^9 to 1 x 10^{11} M(sun). At the lower end, these star formation rates, gas masses, and diameters are similar to those of local ultraluminous infrared galaxies, and represent starbursts in centrally concentrated disks, sometimes, but not always, associated with active galactic nuclei. The evidence for large (> 5 kpc) molecular disks is limited. Morphology and several high angular resolution images suggest that some EMGs are mergers with a massive molecular interstellar medium in both components. A critical question is whether the EMGs, in particular those at the higher end of the gas mass and luminosity distribution, represent the formation of massive, giant elliptical galaxies in the early Universe. The sample size is expected to grow explosively in the era of the Atacama Large Millimeter Array (ALMA)., Comment: 49 pages, 10 figures, to appear Ann. Rev. Ast. & Astrophys. 43 (2005)
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- 2005
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146. Identification of a functional FADS1 3′UTR variant associated with erythrocyte n-6 polyunsaturated fatty acids levels
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Hermant, Xavier, Delay, Charlotte, Flaig, Amandine, Luque-Bedregal, Jimena, Briand, Gilbert, Bout, Marie-Adélaïde, Cottel, Dominique, Wagner, Aline, Arveiler, Dominique, Simon, Chantal, Ferrières, Jean, Ruidavets, Jean-Bernard, Laillet, Brigitte, Amouyel, Philippe, Dallongeville, Jean, Meirhaeghe, Aline, and Dumont, Julie
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- 2018
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147. New constraints on elemental and Pb and Nd isotope compositions of South American and Southern African aerosol sources to the South Atlantic Ocean
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Khondoker, R., Weiss, D., van de Flierdt, T., Rehkämper, M., Kreissig, K., Coles, B.J., Strekopytov, S., Humphreys-Williams, E., Dong, S., Bory, A., Bout-Roumazeilles, V., Smichowski, P., Cid-Agüero, P., Babinski, M., Losno, R., and Monna, F.
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- 2018
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148. A Single Example Can Improve Zero-Shot Data Generation.
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Pavel Burnyshev, Valentin Malykh, Andrey Bout, Ekaterina Artemova, and Irina Piontkovskaya
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- 2021
149. General Nutrition and Fitness for the Child with Rheumatic Disease
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Bout-Tabaku, Sharon
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- 2018
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150. Integration of two-phase solid fluid equations in a catchment model for flashfloods, debris flows and shallow slope failures
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Bout, B., Lombardo, L., van Westen, C.J., and Jetten, V.G.
- Published
- 2018
- Full Text
- View/download PDF
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