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Dermatofibrosarcoma Protuberans is an aggressive form of skin cancer in children. It has a slow growth rate and low chance of metastasizing but is notorious for its aggressive invasive and recurrent nature. In pediatric patients, the resections can be quite aggressive but with appropriate surgical planning and approach, can have quite low morbidity and mortality. We report a unique case of a pediatric patient with dermatofibrosarcoma protuberans that was managed with repeated surgical resections, discuss operative management strategies for this aggressive diagnosis, and provide a review of the literature.

Background: About 63% of people living with mild cognitive impairment (MCI) and dementia live in low- and middle-income countries (LMICs). Emerging evidence suggests that early risk factors for the development of MCI and dementia can be modified by public health and preventive intervention approaches. Aim: This study aimed to assess the prevalence of MCI in older adult patients and its relationship with some risk factors. Setting: The study was conducted among older adults at the Geriatric Clinic of the Family Medicine Department of a hospital in southern Nigeria. Methods: A cross-sectional study was carried out involving 160 subjects aged 65 years and above over a period of 3 months. Socio-demographic and clinical data were obtained using an interviewer-administered questionnaire. Subjects were accessed for impaired cognition using the 10-word delay recall test scale. Data were analysed using SPSS version 23. Results: There were 64 males and 96 females; male to female ratio was 1:1.5. Majority of the study population were in age range of 65–74 years. The overall prevalence of MCI was 59.4%. Respondents with tertiary education were 82% less likely to have MCI on logistic regression analysis (OR = 0.18, 95% CI = 0.465–0.719). Conclusion: Mild cognitive impairment was prevalent among older adults in this study and was found to be significantly associated with low level of education. Contribution: It is therefore recommended that screening for MCI and known risk factors should be prioritized at geriatric clinics.

Abstract Background Poor oral health in pregnancy can be associated with poor pregnancy outcome, however, dental consultation among pregnant women appears to be low. Methods This was a questionnaire-based study of 413 women who attended the antenatal clinic of University of Nigeria Teaching Hospital (UNTH), Ituku/Ozalla, Enugu. The information obtained was analyzed using SPSS version 22. A p-value of less than 0.05 was considered statistically significant. Results Only 36 (8.7%) of the respondents had dental consultations in index pregnancy for complaints such as tooth ache and decay (66.7%) and pain as well as swelling of the gum (33.3%). The most common reason given for not visiting a dentist during the index pregnancy was the visit not being relevant to their pregnancy outcome (69.2%). After counseling them, only 249 (60.3%) agreed to have dental consultation during subsequent pregnancies. The relationship between visiting the dentist and place of residence (

There are concerns about the COVID-19 vaccine's safety, reliability, and efficacy. Previous studies on vaccine hesitancy focused on public perception and factors influencing behavior but little is known about how government response affects acceptance and distribution efforts. Consequently, the present study is focused on providing answers to the question regarding the challenges induced by the Nigerian governments' response to the COVID-19 vaccine distribution and acceptance process. Utilizing an interpretative phenomenological analysis (IPA), Findings showed that even though there are strategies designed to ensure effective rollout of the COVID-19 vaccines to the target populations, the plans are not well laid out. Corruption risks and facility deficiency are the likely problems that might affect efficient COVID-19 vaccine equitable distribution to the target groups. The findings' practical implications indicate that the Nigerian government and other stakeholders ought to make improvements in a number of areas to enable a successful and equitable distribution of the COVID-19 vaccine. This entails enhancing the online registration process, enhancing communication techniques, tackling corruption threats, assuring a steady supply of electricity, and providing employees with the necessary tools and training. [ABSTRACT FROM AUTHOR]

Unlocking the potential of legumes through short‐term germination offers an innovative approach to improving the functionality of the resultant flour. This review examines the multifaceted benefits of short‐term germinated legume flour, emphasizing the enzymatic activities that breakdown complex legume compounds into simpler forms and reduce anti‐nutritional factors. This process improves digestibility, nutrient bioavailability, and health‐promoting properties. Furthermore, short‐term germination enhances the techno‐functional properties of legume flours without compromising their quality, avoiding excessive starch and protein degradation associated with prolonged germination. This review also explores the applications of short‐term germinated legume flours in developing nutritious and healthy food products tailored to diverse dietary needs. Subsequent integration of these short‐term germinated flours into food products provides a route for the development of cost‐effective, nutritious, and sustainable options that can address malnutrition and enhance overall well‐being. [ABSTRACT FROM AUTHOR]

Type II diabetes mellitus (T2DM) has been suggested to predispose to osteoarthritis (OA) leading to T2DM-induced OA. Hence this study aims to develop an experimental model for T2DM-induced OA in order to advance research on diabetes-osteoarthritis conditions. Male Wistar rats (N=40) were divided into control and experimental T2DM group. T2DM was induced by a single intraperitoneal injection of nicotinamide (110 mg/kg) and streptozotocin (65 mg/kg). Rats with fasting blood glucose levels >200 mg/dL on day 4 post-induction were considered diabetic. Glucose levels were subsequently monitored on days 7, 14, 21, 28 post-induction. Feasible osteoarthritis markers; joint swelling diameter, gait test (Stride length and paw dimension), arthritis index, histological evaluations and MANKIN osteoarthritis scores were done; Data were analyzed using Student's t-test and Bonferroni post-hoc test, p < 0.05. Data obtained from T2DM group showed significantly higher blood glucose levels on days 4, 7, 14, 21, and 28 compared with controls. T2DM group experienced increased joint swelling, arthritis index, and decreased stride length, paw width, and paw area. Histological analysis revealed significant knee joint deterioration, including synovium derangement, cartilage abnormalities, and higher MANKIN osteoarthritis scores in the T2DM group compared to controls. This study shows an experimental T2DM-induced OA model in Wistar rats with signs and symptoms consistent with diabetes-induced osteoarthritis in human. [ABSTRACT FROM AUTHOR]

Introduction The effects of homelessness on pregnant women are substantial. We aim to identify key characteristics of a group of women identified as homeless and pregnant in order to understand their history of housing, family composition, health, and demographics as a first step for future intervention. Methods We present cross-sectional survey data on a sample of 100 women reporting homelessness and pregnancy in the prior year in Columbus, Ohio, identified through social service and housing not for profit agencies. Our analysis uses data collected from a survey of health behaviors, housing, employment status, and demographics. Continuous measures are described with means and standard deviations, and categorical variables are described with percentages. Results The majority (81%) of the women identified as African American. Over 95% of the women were single, and 74 women reported a prior pregnancy. Almost half of the women reported being behind on rent at least one time in the last 6 months, and 43% indicated that they had lived in more than three places in the last year. Approximately 34% of the sample reported cigarette use during pregnancy, while 12% and 30% reported alcohol and illicit drug use, respectively. Discussion Women who were pregnant and experiencing homelessness in our study reported a multitude of complex and severe problems ranging from high rates of substance use, longstanding housing insecurity and financial stress. Programs hoping to successfully support women will need to address a variety of service needs while recognizing the resilience of many women., Author(s): Emma Ervin [sup.1] , Barbara Poppe [sup.2] , Amanda Onwuka [sup.1] , Hannah Keedy [sup.1] , Stephen Metraux [sup.3] , Leslie Jones [sup.1] , Megan Sandel [sup.4] , Kelly [...]

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The rapid development of 5G communication networks has ushered in a new era of high-speed, low-latency wireless connectivity, as well as the enabling of transformative technologies. However, a crucial aspect of ensuring reliable communication is the accurate modeling of path loss, as it directly impacts signal coverage, interference, and overall network efficiency. This review paper critically assesses the performance of path loss models in mid-band and high-band frequencies and examines their effectiveness in addressing the challenges of 5G deployment. In this paper, we first present the summary of the background, highlighting the increasing demand for high-quality wireless connectivity and the unique characteristics of mid-band (1–6 GHz) and high-band (>6 GHz) frequencies in the 5G spectrum. The methodology comprehensively reviews some of the existing path loss models, considering both empirical and machine learning approaches. We analyze the strengths and weaknesses of these models, considering factors such as urban and suburban environments and indoor scenarios. The results highlight the significant advancements in path loss modeling for mid-band and high-band 5G channels. In terms of prediction accuracy and computing effectiveness, machine learning models performed better than empirical models in both mid-band and high-band frequency spectra. As a result, they might be suggested as an alternative yet promising approach to predicting path loss in these bands. We consider the results of this review to be promising, as they provide network operators and researchers with valuable insights into the state-of-the-art path loss models for mid-band and high-band 5G channels. Future work suggests tuning an ensemble machine learning model to enhance a stable empirical model with multiple parameters to develop a hybrid path loss model for the mid-band frequency spectrum.

Background: There is a high burden of cervical cancer in our environment. Most patients present late when the prognosis is guarded. Hence, accurate diagnosis of preinvasive lesions from cervical biopsies is important for clinical decisions and patient management. The aim of the study is to correlate the expression of p16INK4a, p53, and Ki-67 with histopathological diagnosis of noninvasive cervical lesions. Materials and Methods: The paraffin blocks of all cervical biopsies (excluding cases histologically diagnosed as invasive lesions) seen in two histopathology laboratories in Nnewi, Southeast Nigeria, over a 10-year period (2011–2020) were retrieved from the archives of both facilities. The cases were subjected to immunohistochemistry using p16INK4a, Ki-67, and p53 monoclonal antibodies. Results: There were 23 normal/reactive (45.1%), 6 low-grade squamous intraepithelial lesion (11.8%), and 22 hIL (43.1%). There is a very strong positive correlation between p16INK4a expression and the histopathological diagnosis (Spearman's correlation = 0.98). There is a strong positive correlation between Ki-67 expression and the histopathological diagnosis (Spearman's correlation = 0.70). There is a weak positive correlation between p53 expression and histopathological diagnosis (Spearman's correlation coefficient = 0.40). Conclusion: p16INK4a shows the best correlation with histopathological diagnosis of noninvasive cervical lesions and may be a very useful adjunct to H and E for diagnosing preinvasive cervical lesions. However, p53 correlates poorly with histopathologically diagnosed noninvasive cervical lesions and therefore may not be diagnostically useful.

Background: There are only a few epidemiological studies published on skin disorders in the elderly within the Nigerian context and none from the Southeast Region of the country. In addition, none of these studies has considered the pattern and frequency of histopathologically diagnosed geriatric skin lesions. Hence, we attempted to determine the frequency as well as the age and gender distributions of histologically diagnosed dermatological diseases in geriatric population from skin biopsies submitted to the histopathology department of a tertiary care hospital in Southeast Nigeria. Materials and Methods: This is a cross-sectional retrospective hospital-based study involving all skin biopsies of patients 60 years and above, received at the Department of Histopathology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria, from January 2004 to December 2019. Results: During the study period, 751 skin biopsies were received in the histopathology department. Of these, 142 were from patients who were older than 60 years. Thus, the overall share of geriatric patients was 18.9%. The mean age at presentation was 71.1 ± 8.6 years. The M: F was 1:1, and most of the patients belonged to the age group of 60–69 years (69 cases, 48.6%). The mean age of the male patients was 72.1 ± 9.5 years. In the female patients, it was 70.1 ± 7.5 years. The most common disease category was neoplasms (91, 64.1%). Most neoplasms were malignant. There were 67/142 (47.2%) malignant lesions. The most common was Squamous cell carcinoma (SCC) (30 cases) which is 21.1% of all geriatric skin biopsies and 44.8% of malignant skin biopsies. This is closely followed by melanoma (29 cases). Conclusion: Malignant neoplasms, benign neoplasms, and papulosquamous disorders are the three most common histologically diagnosed skin lesions in our geriatric population. The most common skin malignancies in this group of patients are SCC and malignant melanoma.

Background: Administration of intermittent preventive treatment (IPT) in pregnancy is recommended for all pregnant women living in areas of stable malaria transmission. In order to increase the chances of a parturient receiving adequate number of IPT in pregnancy, World Health Organization (WHO) now recommends that it should be commenced from second trimester and given every month (at least 4 weeks apart) until the time of delivery, however, this recommendation is not being practiced by all doctors attending to pregnant women. Objective: To determine the conformity of Doctors to monthly prescription of IPT till delivery. Materials and Methods: This was a cross-sectional survey of antenatal clinic Doctors’ prescription of IPT during pregnancy in Enugu state. Information obtained included the socio-demographic characteristics of the Doctors, knowledge of IPT in pregnancy for malaria and implementation of the new IPT policy. A P-value of

Background: This study assessed the hepatic vein waveform (HVW) and mean maximum portal vein velocity (MM-PVV) on Doppler ultrasound in patients with liver cirrhosis (LC) and compared it with that of age and sex-matched controls. It correlated the degree of HVW abnormality and MM-PVV changes with liver function based on Child-Turcotte-Pugh (CTP) to determine which was more predictive of CTP. Methods: Sixty patients with LC and 60 healthy controls were consecutively recruited into this study. Each patient was classed based on the CTP system after relevant tests. Doppler evaluation of the hepatic vein (HV) and MM-PVV were performed. HVW obtained was classified either into triphasic, biphasic, or monophasic. Results: Sixty cirrhotic and 60 age-matched control subjects aged 19–69 and 18–69 years, respectively, completed this study. All control subjects had a normal HVW pattern while 46 (76.7%) cirrhotic subjects had abnormal HVW (P < 0.001). The MM-PVV was significantly lower in cirrhotic subjects than in controls; 22.8 cm/s versus 33.6 cm/s (P < 0.001). The degree of HVW abnormality among cirrhotics showed a significant positive correlation with CTP (r = 0.283, P = 0.029). MM-PVV on the other hand showed no correlation with CTP class (r = −0.124; P = 0.346). Linear regression showed that HVW was a significant predictor of hepatic dysfunction based on CTP. Conclusion: Changes in the waveform pattern of the HVs are a good predictor of the derangement of hepatic function in patients with LC than changes in PVV. HVW pattern could therefore serve as an adjunct to CTP class in hepatic function assessment.

Background: Ovarian ectopic pregnancy is a rare form of non-tubal ectopic pregnancy. It can rupture before the end of the first trimester, causing hemoperitoneum, and present with signs and symptoms similar to other commoner abdominal emergencies or the pregnancy can continue intraperitoneally. Therefore, they are not often diagnosed preoperatively. Ultrasound can assist in diagnosis of ovarian ectopic pregnancy but the findings could be ambiguous or inconclusive. We present a case of ruptured ovarian ectopic pregnancy at the second trimester causing massive hemoperitoneum that was suspected as an intrabdominal malignancy co-existing with intrabdominal pregnancy. Case presentation: She was a 34 year-old Nigerian unbooked G4P3+0, (3 alive), who presented to the labor ward on 21st January, 2021 with a complaint of a 6-week history of abdominal pain and swelling. Pain was insidious in onset, generalized, non-colicky, non-radiating, constant, no known aggravating or relieving factor, but it was of moderate intensity. She had amenorrhea with a positive serum pregnancy test without prior early ultrasound. At presentation, initial abdominopelvic ultrasound revealed intra-uterine viable pregnancy but repeat ultrasound done showed a left adnexal ectopic gestation and an echo-rich intraperitoneal fluid collection. Laparotomy was done and ovarian pregnancy was accurately diagnosed intra-operatively. Tissue samples from the ovary confirmed normal products of conception, namely chorionic villi, trophoblastic cells and ovarian stroma at histology. Conclusion: Despite advances in imaging techniques, the diagnosis of ovarian ectopic gestation is still very difficult. When premenopausal women present with amenorrhea, generalized non-colicky abdominal pain and swelling in combination with ambiguous findings of pregnancy on ultrasound in the absence of trauma, differential diagnoses should include ruptured ovarian pregnancy. Obstetricians should maintain a high index of suspicion to forestall delayed diagnosis and the potential maternal morbidity and mortality. However, the need for high-index of suspicion should be for any ectopic, not just ovarian pregnancy.

BackgroundTo our knowledge, there is no prior randomized trial on the efficacy of Mojeaga remedy (a special blend of Alchornea cordifolia, Pennisetum glaucum and Sorghum bicolor extracts) when co-administered with standard-of-care for correction of anemia in obstetrics practice. This study determined the efficacy, safety and tolerability of Mojeaga as adjunct to conventional oral iron therapy for correction of anemia in obstetric population.MethodsA pilot open-label randomized clinical trial. Participants with confirmed diagnosis of anemia in three tertiary hospitals in Nigeria were studied. Eligible participants were randomized 1:1 to either Mojeaga syrups 50 mls (200mg/50mls) administered three times daily in conjunction with conventional iron therapy (Mojeaga group) for 2 weeks or conventional iron therapy alone without Mojeaga (standard-of-care group) for 2 weeks. Repeat hematocrit level were done 2 weeks post-initial therapy. Primary outcome measures were changes in hematocrit level and median hematocrit level at two weeks post therapy. Maternal adverse events and neonatal outcomes (birth anomalies, low birthweight, preterm rupture of membranes and preterm labor) were considered the safety outcome measures. Analysis was by intention-to-treat.ResultsNinety five participants were enrolled and randomly assigned to the Mojeaga group (n = 48) or standard-of-care group (n = 47). The baseline socio-demographic and clinical characteristics of the study participants were similar. At two weeks follow-up the median rise in hematocrit values from baseline (10.00±7.00% vs 6.00±4.00%;p0.05).ConclusionMojeaga represents a new adjuvants for standard-of-care option for patients with anemia. Mojeaga remedy is safe for treating anemia during pregnancy and puerperium without increasing the incidence of congenital anomalies, or adverse neonatal outcomes.Clinical trial registrationwww.pactr.samrc.ac.za: PACTR201901852059636 (https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=5822).

The calcium-selective ion channel Orai1 has a complex role in bone homeostasis, with defects in both bone production and resorption detected in Orai1 germline knock-out mice. To determine whether Orai1 has a direct, cell-intrinsic role in osteoblast differentiation and function, we bred Orai1 flox/flox (Orai1fl/fl) mice with Runx2-cre mice to eliminate its expression in osteoprogenitor cells. Interestingly, Orai1 was expressed in a mosaic pattern in Orai1fl/fl-Runx2-cre bone. Specifically, antibody labeling for Orai1 in vertebral sections was uniform in wild type animals, but patchy regions in Orai1fl/fl-Runx2-cre bone revealed Orai1 loss while in other areas expression persisted. Nevertheless, by micro-CT, bones from Orai1fl/fl-Runx2-cre mice showed reduced bone mass overall, with impaired bone formation identified by dynamic histomorphometry. Cortical surfaces of Orai1fl/fl-Runx2-cre vertebrae however exhibited patchy defects. In cell culture, Orai1-negative osteoblasts showed profound reductions in store-operated Ca2+ entry, exhibited greatly decreased alkaline phosphatase activity, and had markedly impaired substrate mineralization. We conclude that defective bone formation observed in the absence of Orai1 reflects an intrinsic role for Orai1 in differentiating osteoblasts.

Abstract Background The use of active carbons derived from waste biomass as adsorbents in the remediation of wastewater remains a valuable and cost-effective technology when compared to the use of commercial active carbon for the same purpose. This research aims at using a 2-level full factorial design (FFD) to efficiently evaluate factors that influence the preparation of active carbon from the waste pods of the Dialium guineense seeds. The influence of three preparation factors (concentration of the activating agent, activation time, and type of activating agent) on the active carbon yield and its adsorption capacity for methylene blue were investigated. Based on the full factorial design, two regression models were developed to correlate the factors to the two responses. From an analysis of variance (ANOVA), the most significant factors influencing each response were identified. The active carbon preparation conditions were then optimized by maximizing both the active carbon yield and its adsorption capacity for Methylene Blue. The functional group and surface morphology of the active carbon prepared under the predicted optimum conditions was analyzed via Fourier Transform Infra-Red (FTIR) spectroscopy and Scanning Electron Microscopy (SEM) respectively. Results The results of this study revealed that the concentration of the activating agent had the most significant effect on the yield of the active carbon produced as well as on its adsorption capacity for methylene blue. The optimum preparation process conditions were found to be: concentration of activating agent 5M, activation time 30 min and activating agent, NaOH which resulted in an active carbon yield of 21.25%, and an adsorption capacity of 9.33509 mg MB per gram of active carbon. SEM and FTIR showed evidence of successful activation. Conclusion The preparation of Dialium guineense seed pods' active carbon is strongly influenced by concentration and type of activating agent used. Reliable statistical models based on the FFD proved to be useful in identifying factors that significantly influence the preparation of Dialium guineense seed pods' active carbon. The active carbon holds great potential for application in the elimination of hazardous synthetic dyes from wastewater and should be explored further.

Reading is one of the important skills of language. It is a basic tool of education whether formal or informal. Reading is a receptive skill, which involves the ability to meaningfully interpret or decode written or graphic symbols of language. Through reading, the hidden treasure of knowledge is unfolded; knowledge is gained thereby empowering individuals to share and also participate in the world's universal culture and civilization. It is, therefore, of paramount importance that every one, including children, imbibe reading culture so as to unlock the world, treasure of knowledge. This study is of great importance as today's children spend hours trapped under derivative distractions such as television, computers, and associated technologies targeted to children. It becomes then imperative to reawaken reading culture among the children who are faced with competing leisure time choices. One of the ways of helping children to imbibe reading culture is to get them reading ready. This paper focuses on the causes of reading readiness deficiency and ways of improving reading readiness in children. The paper identified factors such as socio-economic background, physical abnormalities, mental imbalance, lack of interest, and unfamiliarity with symbols and teachers' inability to help children as causes of reading readiness deficiency in children. The paper also suggested ways of improving reading readiness and recommended that parents should provide books and stimulating reading environments for their children and helps them cultivate the habit of using their leisure to read for pleasure. It was also recommended among others that teachers must acknowledge the indispensability of reading skills and as such plan an effective programme of reading instruction which should focus on promoting reading culture among children in their schools.

INTRODUCTION: Climate smart agriculture (CSA) which involves the integration of IoT and cloud computing is an emerging agricultural paradigm that is foreseen to be the main driver of agriculture as the 21st century progresses. Sub-Saharan Africa lags in this regard and therefore deserves a special focus. OBJECTIVES: This paper presents an overview of Internet-of-Things (IoT) solutions in CSA in the context of food security in sub-Saharan Africa (SSA) METHODS: An overview of the status of food insecurity in SSA and associated factors is presented. The paper then focused on IoT as a technology and how it can be used for CSA in SSA through use cases; possible challenges were also examined. RESULTS: The paper showed that with CSA, SSA can become a net exporter of food. CONCLUSION: The paper concludes with open issues like the funding of research and development which must be addressed if SSA is to leverage IoT technology to attain food security.

Albinism results from a deficiency of the protein responsible for melanin production in melanocytes. Albinos are at an increased risk of dermatoses and malignancies. Primary carcinosarcoma of the skin is an exceedingly rare biphasic tumor composed of malignant epithelial and mesenchymal elements with an unclear histogenesis. To our knowledge, this has not been reported in an African albino. Here, we report the index case of this rare tumor in an albino of African descent.

Background: Early booking in the first trimester is recommended, and it is known to be of great benefit for the mother and the fetus. Aim: The aim of this study was to determine the profile and predictors of early prenatal booking among pregnant women in Enugu, Nigeria. Materials and Methods: A cross-sectional study was conducted on 200 consecutive pregnant women attending booking clinic at the University of Nigeria Teaching Hospital, Enugu, Nigeria. Statistical analysis was both descriptive and inferential at 95% confidence level, and carried out using the Statistical Package for the Social Sciences (SPSS) software, version 22.0, IBM SPSS, Chicago, Illinois. A P value of less than 0.05 was considered statistically significant. Results: The mean gestational age at booking was 18.6 ± 8.4 weeks. Although 37% (n = 74) of the women booked early in the first trimester; only 36% of the respondents (n = 72) were aware of the right time to book for prenatal care. More than half (56.8%, 42 of 74) of the women, who booked early for prenatal care, had problems in their last pregnancies, whereas 43.2% (n = 32 of 74) of them had problems in their index pregnancies. Parity, secondary level of education, and problems in the previous and index pregnancies were significantly associated with early booking after adjusting for other variables in the multiple logistic regression analysis (P < 0.05). Conclusion: Pregnant women in Enugu still book late for prenatal care. There is a need to create more awareness in this regard among women of reproductive age. Factors contributing to early booking in Enugu, include parity, secondary level of education as well as problems in the previous and index pregnancies.

Adverse cutaneous reactions to medications are not uncommon and may resemble viral infection and vice versa, complicating diagnosis. We describe the case of a 79-year-old male with cholangiocarcinoma with liver and presumed lung metastasis who presented with abdominal pain and was admitted with ileitis with partial small bowel obstruction. He had a widespread papulovesicular rash with hemorrhagic center, mostly on his face, chest, and back. The rash was initially thought to be a drug eruption, but was eventually diagnosed via dermatopathological examination as disseminated varicella zoster virus (VZV) infection. Steroid treatment was discontinued, and airborne precautions were initiated. Polymerase chain reaction for VZV was obtained and intravenous acyclovir treatment was begun. This case of VZV, initially suspected to be an adverse drug reaction, highlights the importance of early identification of a highly infectious lesion and the importance of early infection control measures, given the implications of exposure to VZV for health care personnel.