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Copyright of Journal of East China University of Science & Technology is the property of Journal of East China University of Science & Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the effects of Naomaili granule combined with butylphthalide soft capsule on cerebral hemodynamics, vascular endothelial function and nerve injury markers in patients with acute cerebral infarction. Methods: This study was a prospective design, and 150 patients with acute cerebral infarction who were admitted in our hospital from January 2021 to June 2022 were selected. According to the random number table method, they were divided into control group (conventional basic treatment combined with butylphthalide soft capsule treatment) and observation group (conventional basic treatment combined with Naomaili granule combined with butylphthalide soft capsule treatment), 75 cases in each group. The efficacy, National Institutes of Health Neurological deficit (NIHSS) score, Activity of daily Living scale (ADL) score and medication safety in the groups were observed. At the same time, The changes of cerebral hemodynamics, vascular endothelial function and nerve injury markers before and after treatment in the two groups were observed. Results: The total effective rate in the observation group was 96.00%, which was significantly higher than 84.00% in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions in the two groups (P>0.05). After treatment, the ADL score in the observation group was higher than that in the control group at the same period, the NIHSS score was lower than that in the control group at the same period (P<0.05). After treatment, the peak systolic blood flow velocity (Vs), diastolic blood flow velocity (Vd) and average blood flow velocity (Vm) in the observation group were higher than those in the control group at the same period (P<0.05). After treatment, endothelin-1 (ET-1) in the observation group was lower than that in the control group at the same period, nitric oxide (NO) were higher than those in the control group at the same period (P<0.05). After treatment, neuron-specific enolase (NSE), glial fibrillary acidic protein (GFAP) and central nervous system specific protein (S100β) in the observation group were lower than those in the control group at the same period (P<0.05). Conclusion: Naomaili granule combined with butylphthalide soft capsule can effectively improve cerebral hemodynamics, vascular endothelial function and nerve injury in patients. [ABSTRACT FROM AUTHOR]

【Objective】 The study aimed to compare the anti-inflammatory activities of six extracts from Panax species in vitro and in vivo, and to explore the anti-inflammatory mechanism. 【Method】 The viability of RAW264.7 cells was detected by CCK-8 method.NO release was detected by Griess method. The secretion of inflammatory factors was detected by ELISA. The expressions of key proteins were detected by Western blot. 【Result】 At concentrations of 0.02 and 0.20 mg/mL, six extracts from Panax species showed no significant inhibitory effect on RAW264.7 cell viability (P＞0.05). Six extracts significantly inhibited the increase of NO content in the supernatant of RAW264.7 cells induced by LPS at a concentration of 0.2 mg/mL (P＜0.05 or P＜0.01 or P＜0.001), with Panax stipuleanatus having the strongest inhibitory effect. Compared with LPS group, six extracts significantly reduced TNF-α content in cells (P＜0.01 or P＜0.001). P.stipuleanatus group and P.japonicus group demonstrated obviously down-regulated p-NF-κB and IκBα protein expressions, while P.japlcus group and P.japonicus group significantly inhibited NF-κB protein expression. In addition, six extracts showed dose-dependent inhibitory effect on xylene induced ear swelling in mice. The inhibitory rates of P.stipuleanatus group, P.notoginseng group, P.quinquefolius group, and P.japonicus group on mouse ear swelling were 91.11%, 68.89%, 82.22%, and 64.44%, respectively. The HE staining results of mouse ear tissue showed that the model group showed significant connective tissue edema, increased gaps, and inflammatory cell infiltration in the ear tissue. Compared with the model group, six extracts reduced edema reactions and inflammatory cell infiltration, with P.stipuleanatus group having the best improvement effect. 【Conclusion】 Six Panax species have anti-inflammatory effects in vivo and in vitro, and there are differences in anti-inflammatory activities. The mechanism may be related to the regulation of NF-κB signaling pathway. [ABSTRACT FROM AUTHOR]

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Command Control & Simulation / Zhihui Kongzhi yu Fangzhen is the property of Command Control & Simulation Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plastics Science & Technology / Suliao Ke-Ji is the property of Plastics Science & Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ecology & Rural Environment is the property of Journal of Ecology & Rural Environment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Remote Sensing is the property of Editorial Office of Journal of Remote Sensing & Science Publishing Co. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effects of path functional training combined with intermittent pneumatic device intervention on the rehabilitation effect and the occurrence of deep venous thrombosis (DVT) in the patients with lumbar vertebral fusion surgery.Methods A total of 120 patients with lumbar vertebral fusion surgery admitted an treated in this hospital from July 2020 to July 2021 were selected as the study subjects and divided into the observation group and control group by adopting the random number table method, 60 cases in each group.The control group adopted the traditional intervention, and the observation group adopted the path functional training combined with intermittent pneumatic device intervention.The reaching standard rate of functional exercise, Oswestry dysfunction index score (ODI),occurrence rates of complications（ incision infection, DVT,constipation and urinary system infection） and clinical indicators（hospitalization duration and time for getting out of bed） after intervention were analyzed and compared between the two groups. Results The hospital stay duration and time for getting out of bed after intervention in the observation group were shorter than those in the control group, the reaching standard rate of functional exercise was significantly higher than that in the control group, the ODI score and occurrence rate of complications were significantly lower than those in the control group, and the differences were statistically significant（P＜0.05）.Conclusion Adopting the path functional training combined with intermittent pneumatic device intervention in the patients with lumbar vertebral fusion surgery is beneficial to the functional rehabilitation, reduce the occurrence rate of DVT, and could be widely promoted and applied. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Practical Medicine / Shiyong Yixue Zazhi is the property of Journal of Practical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of Botanical Research is the property of Bulletin of Botanical Research Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Computer Measurement & Control is the property of Magazine Agency of Computer Measurement & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Power Generation Technology is the property of Power Generation Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The experiment was to study the optimum proportion and time of compound feed for three kinds of probiotics. In the experiment, the feed of Cynoglossus semilaevis was used as substrate, the total inoculum amount was 3%, and the fermentation treatment of Saccharomyces cerevisiae, Bacillus subtilis and Lactobacillus plantarum was carried out at 35 ℃, while the control group was not inoculated with any inoculum. A total of 300 healthy Cynoglossus semilaevis with an average body weight of (80.27±0.19) g were randomly divided into two groups, with three replicates in each group and 50 Cynoglossus semilaevis in each replicate. The control group was fed with complex diet, and the experimental group was fed with complex diet supplemented with 10% fermented feed (fermented feed under the optimal conditions obtained in the optimization experiment). The experiment lasted for 56 d. The results showed that after fermentation, the number of live bacteria in each group of fermented food increased by about 100 000 times. The mixed fermentation effect of three strains was significantly better than that of control group (P<0.05). The fermentation effect was the best when the ratio of Saccharomyces cerevisiae∶ Bacillus subtilis∶ Lactobacillus plantarum was 1∶ 3∶ 2 for 5 d. Compared with control group, the body weight gain and specific growth rate of Cynoglossus semilaevis in test group were significantly higher (P<0.05). The experiment indicates that the fermentation effect of Saccharomyces cerevisiae∶ Bacillus subtilis∶ Lactobacillus plantarum at a ratio of 1∶3∶2 for 5 d is better at 35 ℃, and the fermentation feed can promote the growth and improve the feed utilization rate of Cynoglossus semilaevis. [ABSTRACT FROM AUTHOR]

Metabolic-associated fatty liver disease (MAFLD) has become one of the major causes of chronic liver disease worldwide. It is crucial to accurately differentiate non-alcoholic fatty liver, steatohepatitis and MAFLD-associated liver cirrhosis. Due to the invasiveness and sampling error of liver biopsy, non-invasive diagnostic method of MAFLD is an ideal alternative. In this article, research progress on the application of magnetic resonance imaging (MRI) in the assessment of hepatic steatosis, inflammation and fibrosis in MAFLD patients were reviewed, aiming to provide evidences for non-invasive diagnosis of MAFLD in clinical practice. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Xinjiang Agricultural Sciences is the property of Xinjiang Agricultural Sciences Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的：研究甲状腺低分化癌（poorly differentiated thyroid carcinoma, PDTC）和原发性甲状腺淋巴瘤（primary thyroid lymphoma,PTL）的临床表现和超声特征，探讨高频彩色多普勒超声对PDTC和PTL的鉴别诊断价值。方法：回顾性分析2017年4月—2021年11月在南京医科大学第一附属医院及南京其他两所医院进行检查并治疗的PDTC患者19例和PTL患者31例。收集所有患者临床表现和超声特征，并与病理结果对照，比较两组临床表现和超声特征的差异。结果：淋巴瘤组平均年龄为（53±16）岁，低分化癌组平均年龄为（68±9）岁。通过统计学分析发现年龄、是否合并桥本氏甲状腺炎、颈静脉有无癌栓、气管有无侵犯、发病部位、边界、是否钙化、是否有囊性变等在两组间差异有统计学意义。PTL患者发病年龄较PDTC早，且甲状腺基础背景多合并桥本氏甲状腺炎，多为双侧叶发病。PDTC的患者中囊性变、边界不清、钙化、合并颈静脉癌栓、气管侵犯的发生率更高（P <0.05）。而性别、颈部是否突然增大史、是否有周围组织压迫史、是否合并淋巴结病变、发病叶是否增大、病灶数目、最大左右径、内部回声、形态、血流分级等，两组差异无统计学意义（P> 0.05）。结论：高分辨率超声检查是诊断及鉴别诊断甲状腺结节最敏感的首选检查方法，掌握PDTC与PTL的临床表现及超声特征，有助于对PDTC和PTL早发现、早诊断、早治疗。 [ABSTRACT FROM AUTHOR]

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of China University of Petroleum is the property of China University of Petroleum and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Guihaia is the property of Guihaia Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Xi'an Jiaotong University (Medical Sciences) is the property of Xian Jiaotong University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate expression changes and molecular mechanism of phosphatase and tensin homology deleted on chromosome 10 (PTEN) and matrix metalloproteinase-2 (MMP-2) in lymph node invasive non-smallcell lung cancer (NSCLC) H1299 cells. Methods RT-qPCR and Western blotting were used to determine the mRNA and protein expression levels of PTEN and MMP-2 in NSCLC cells without lymph node metastasis (A549) and NSCLC cells with lymph node metastasis (H1299). Lentiviral-mediated lipofection technique was used to make the PTEN over-expressed in H1299 cells (the up-regulated PTEN group). H1299 cells which were transfected with vector plasmid were taken as the control group. The mRNA level of MMP-2 was detected by RT-qPCR and the protein expression levels of PTEN, MMP-2, Akt and p-Akt were detected by Western blotting. NF-κb was determined by using luciferase reporter gene experiment. Results Compared with A549 cells, the relative expression levels of PTEN mRNA and protein in H1299 cells de⁃ creased and the relative expression levels of MMP-2 mRNA and protein in H1299 cells increased (all P<0. 01). Compared with the control group, the protein expression of PTEN increased, the mRNA and protein expression levels of MMP-2, and the protein expression of p-Akt decreased in the up-regulated PTEN group (all P<0. 01). Meanwhile, the activity of NFκB luciferase was lower in the up-regulated PTEN group than in the control group (P<0. 01). Conclusions The relative expression of PTEN decreased and the relative expression of MMP-2 increased in lymph node invasive NSCLC H1299 cells. The over-expression of PTEN can inhibit the expression of MMP-2 by Akt/NF-κb signal pathway. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effect of dexmedetomidine combined with different doses of midazolam on hemodynamics, postoperative inflammatory mediators and cognitive function in patients with non-small cell lung cancer (NSCLC). Methods: NSCLC patients (n=120) who came to the First Affiliated Hospital of Zhengzhou University for surgical treatment from January 2019 to February 2021 were included and divided into low-dose group (n=60) and high-dose group according to different anesthesia regimens Group (n=60), both groups were given dexmedetomidine, on this basis, the low-dose group was given 0.05 mg/kg midazolam, and the high-dose group was given 0.10 mg/kg midazolam. The hemodynamics, inflammatory mediators, cognitive function, recovery quality and incidence of adverse reactions were compared between the two groups. Results: The heart rate (HR) and mean arterial pressure (MAP) increased and then decreased at the time points from 10 minutes after induction of anesthesia (T1) to 5 minutes after extubation (T3) in the two groups, and immediately after extubation (T2) and T3 time points The high-dose group was lower than the low-dose group (P<0.05). The visual analogue scale (VAS) score of pain after awakening in the high-dose group was lower than that in the low-dose group, and the eye opening time, extubation time, and anesthesia recovery room (PACU) stay time were all shorter than those in the low-dose group (P<0.05). The levels of interleukin-1 (IL-1), C-reactive protein (CRP), and tumor necrosis factor-α (TNF-α) in the two groups increased before operation, 3 days after operation, and 7 days after operation, and then decreased, and 3 days after operation., 7 days after operation in the high-dose group was lower than that in the low-dose group (P<0.05). There was no significant difference in the Mini Mental State Scale (MMSE) scores between the two groups at 1 day, 3 days and 7 days after operation (P>0.05). There was no statistical difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Compared with 0.05 mg/kg midazolam, dexmedetomidine combined with 0.10 mg/kg midazolam in patients with NSCLC surgery can maintain hemodynamic stability, improve the quality of recovery, and reduce inflammatory stress. The effect is more significant, and it does not increase the incidence of cognitive impairment and adverse reactions. [ABSTRACT FROM AUTHOR]