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Copyright of New Building Materials / Xinxing Jianzhu Cailiao is the property of New Building Materials Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore whether miR-134-3p regulates the survival and migration of colon cancer cells through targeting ADAM9/EGFR/AKT pathway. Methods Real-time qPCR was used for detecting the miR- 134-3p expression in the normal colonic epithelia (NCM460) and colon cancer cells (SW480, HCT116 and RKO). Meanwhile, Western blot was used for measuring the protein expressions of ADAM9, EGFR and AKT in these cells. Subsequently, cells were transfected with miR-134-3p mimic/miR-134-3p inhibitor, cell proliferation, apoptosis and migration were examined by CCK-8 kits, flow cytometry and Transwell migration assays, respectively. Next, the protein expressions and phosphorylation of ADAM9, EGFR and AKT were measured to evaluate the activation of ADAM9/EGFR/AKT pathway. Finally, the relationship between miR-134-3p and ADAM9 was verified with luciferase assay. Results MiR-134-3p was significantly down-regulated in the three colon cancer cells compared to the normal colonic epithelia NCM460 cells (P<0.05). In contrast, the expressions of ADAM9, EGFR and AKT increased by 2-3 folds in cancer cells compared with NCM460 cells (P <0.05). The proliferation capability of SW480 cells decreased and the count of migrated cells reduced after miR-134-3p mimic transfection. Cell apoptosis percentage elevated to (15.0±1.1)%, which was significantly higher than that of the control (9.0±1.7)% (P< 0.05). In addition, there was a significant decrease in ADAM9, p-EGFR/EGFR and p-AKT/AKT compared with the control (P<0.05). Luciferase assay confirmed that miR-134-3p could bind to ADAM9 mRNA to suppress its expression. However, miR-134-3p inhibitor showed the opposite effect against miR-134-3p mimic transfection in SW480 cells. Conclusion miR-134-3p inhibited survival and migration of colon cancer cells through targeting ADAM9 and the subsequent EGFR/AKT signaling. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Southern Agriculture is the property of Journal of Southern Agriculture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Telecommunication Engineering is the property of Telecommunication Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate effect of bi-level positive airway pressure combined with seretide on immune function, quality of life and respiratory failure symptoms of patients with COPD complicated with type II respiratory failure. Methods: 157 patients with COPD complicated with type II respiratory failure in our hospital from June 2012 to December 2016 were divided into observation group (n=79) and control group (n=78) according to the random number table method, the patients in the control group were treated with routine treatment such as relieving asthma, relieving spasm, resolving phlegm and anti infection, and combined with Bi-PAP treatment, the patients in the observation group were treated with seretide treatment on the basis of the treatment plan in the control group. Respiratory failure symptoms, immune function and quality of life were compared between the two groups before and after treatment. Results: The effective rate of the observation group after treatment was 89.87% (71/79), which was significantly higher than that of the control group 73.08%(57/78)(P<0.05). After treatment, the respiratory rate, heart rate, arterial partial pressure of carbon dioxide in the two groups were lower than before treatment, and the arterial partial pressure of oxygen was higher than before treatment, and the respiratory rate, heart rate and arterial partial pressure of carbon dioxide in the observation group were lower than those in the control group, and the arterial partial pressure of oxygen was higher than that of the control group (all P<0.05). After treatment, levels of serum immunoglobulin M (IgM),immunoglobulin G (IgG) and immunoglobulin A (IgA) of patients in two groups were significantly higher than those before treatment, and the levels of IgM, IgA and IgG in the observation group after treatment were higher than those in the control group (all P<0. 05). Over time, the St.George Hospital Respiratory Questionnaire (SGRQ) score in the two groups after treatment was decreased gradually, and the SGRQ scores of the observation group at 3 months and 6 months after treatment were lower than that of the control group (all P<0.05). Conclusion: Bi-PAP combined with Seretide can significantly improve the symptoms of respiratory failure in patients with COPD complicated with type II respiratory failure, improve immune function and quality of life of patients, clinical application value is high. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Based on a 1420mm tandem cold rolling mill in a domestic plant， rolling processes in an UCM mill were simulated by 3D elastic-plastic finite element method(FEM). Effects of work roll bending(WRB)， intermediate roll bending(IRB)and intermediate roll shifting(IRS)on the rolling pressure were investigated. The results showed that peak values of rolling pressure near the strip edge disappear and the central rolling pressure increases with increasing of WRB， and the saddle-shaped distribution of rolling pressure becomes a convex-shaped distribution. Rolling pressure is hardly affected by IRB， and its distribution form is not changed basically. The sharply increased trend of rolling pressure near the strip edge is eliminated due to IRS， and the steep pressure field becomes smooth. Rankings of effects of the three actuators on rolling pressure are: WRB>IRS>IRB， which is in good agreement with the comparison of actuator efficiencies， and it shows that the working mechanism of controlling strip shape is achieved by affecting the rolling pressure distribution. [ABSTRACT FROM AUTHOR]

Objective: To explore the clinical efficacy and safety of posterior vertebral pedicle screw fixation in the treatment of thoracolumbar burst fracture. Methods: 64 cases of thoracolumbar burst fracture treated in our hospital from January 2014 to December 2016 were selected.which were divided into study group (n=32) and control group (n=32). The study group was treated by posterior vertebral pedicle screw fixation, the control group was treated by posterior vertebral pedicle screw pedicle screw fixation. The patients were followed up for 6 months. The clinical indicators, complications were compared between the two groups. The height ratio of anterior margin of injured vertebra, Cobb angle and Numeric Pain Rating Scale (NRS) scores of the two groups before operation. 1 month after operation. 6 months after operation were compared. Results: All the patients were all healed in I stage and no infection after operation. Compared with the control group, the operation time of the study group was longer (P<0.05), and there was no significant difference between the amount of bleeding and the time of hospitalization (P>0.05). There was no significant difference between the height ratio of anterior margin of injured vertebra. Cobb angle and NRS scores of the two groups (P>0.05). 1 month after operation. 6 months after operation, the height ratio of anterior margin of injured vertebra in the two groups were higher than before operation. Cobb angle and NRS scores were lower than before operation, the differences were statistically significant (P<0.05). 6 months after operation, the Cobb angle. NRS scores in the study group were lower than that in the control group (P<0.05). and there was no significant difference in the height ratio of anterior margin of injured vertebra of the two groups (P>0.05). Compared with the control group, the incidence rate of lumbago and back pain and internal fixation failure in the study group were lower than that in the control group (P<0.05). Conclusion: For thoracolumbar burst fractures .posterior vertebral pedicle screw fixation can effectively improve clinical indicators, is conducive to postoperative physical recovery.pain relief and safety, and is worthy of clinical promotion. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In view of the problem of large residual stress in laser melting deposition, this paper summarizes the mechanism and the effective methods of eliminating the stress. Based on the principle of electromagnetic field, the method utilising electromagnetic field to assist laser melting deposition is proposed in order to reduce the residual stress. The process of laser melting deposition assisted by electromagnetic field is simulated using ANSYS parametric programming language APDL, and the temperature field and the change rule of residual stress are analyzed. The results show that the axial electromagnetic force can effectively reduce the residual stress in the workpiece. Method of X ray diffraction combined with electrolytic corrosion is used to measure the residual stress, and the test results verify the effectiveness of the assisted electromagnetic field. [ABSTRACT FROM AUTHOR]

The construction of laboratory research service platform is a complicated and systematic work. With the practice research on Key Laboratory of Humid Subtropical Eco-geographical Process, Ministry of Education, the personal, finance and material management of the laboratory were summarized. We established and perfected the management mechanism of large-scale instruments, including the unified centralized management platform, large equipment reservation management,centralized procurement management, the person (Group) responsibility for large scale instruments, the construction and management of laboratory team; a long-term mechanism establishment for expanding the operating funds; communication of science knowledge. The solutions were put forward to emancipate the mind, learn from the excellent platform management experience, establish experimental technical team incentive mechanism,optimize of experimental resources, and establish and improve the quality of supervision and evaluation mechanism. We are exploring actively the construction of "open, flow, joint and competition" platform to serve science research. [ABSTRACT FROM AUTHOR]

Copyright of Electronic Components & Materials is the property of Electronic Components & Materials and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coal Science & Technology (0253-2336) is the property of Coal Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Research & Exploration in Laboratory is the property of Research & Exploration in Laboratory and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The multivariable control for hydraulic looper system which has the features of nonlinearity， strong coupling and uncertainty is the difficult point in the rolling control field. In order to improve the control performance of hot continuous rolling strips， a virtual prototype model of the hydraulic looper was built by using ADAMS， then the iterative learning control(ILC)system based on a non-interactive decoupling strategy was designed by using MATLAB， thus a co-simulation model was built by using ADAMS/Sub module and MATLAB/Simulink interface. Simulation studies were made for traditional PID control system and for the designed control system on the basis of this co-simulation model.The simulation results showed that the designed control system further weakens the coupling effect between the looper height and tension， and achives better control effect of the looper system. [ABSTRACT FROM AUTHOR]

Objective To investigate the effect of PRP combined with h UC-MSCs transplantation on the healing of osteoporotic fracture in rats. Methods Fifty female SPF grade SD rats were randomly divided into 5 groups, 10 rats in each group: The sham operation group was only resected ovarian tissues; The placebo group was injected with saline; The non-induction group transplanted withuninducedhUC-MSCs; The PRP + induction group transplanted withh UC-MSCs combined with PRP. After the OPF model was successfully constructed, cells were transplanted 3 times in each group,1 week, 3 weeks and 7 weeks after fracture. Micro-CT analysis was performed every two weeks after fracture. Results Micro-CT analysis results showed that the amount of callus formation in PRP + induction group was significantly increased than that in the other groups. Clinicalhealing criteria was achieved at 11 weeks post-fracture, while other groups callus remodeling phase is lagging behind. The bone healing time in rats was delayed for at least 37.5% compared with normal fracture animals. Conclusion PRP combined with h UC-MSCs transplantation promote osteoporotic fracture healing in rats. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Zhejiang University. Humanities & Social Sciences / Zhejiang Daxue Xuebao is the property of Zhejiang University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Mechanical & Electrical Engineering is the property of Mechanical & Electrical Engineering Magazine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Wool Textile Journal is the property of National Wool Textile Science & Technology Information Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Wuhan University Journal. Humanity Sciences / Wuhan Daxue Xuebao. Renwen Kexue Ban is the property of Wuhan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Zhejiang University. Humanities & Social Sciences / Zhejiang Daxue Xuebao is the property of Zhejiang University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Veterinary Science / Zhongguo Shouyi Xuebao is the property of Chinese Society of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)