Search

The global COVID-19 pandemic has taken a heavy toll on health, social, and economic costs since the end of 2019. Predicting the spread of a pandemic is essential to developing effective intervention policies. Since the beginning of this pandemic, many models have been developed to predict its pathways. However, the majority of these models assume homogeneous dynamics over the geographic space, while the pandemic exhibits substantial spatial heterogeneity. In addition, spatial interaction among territorial entities and variations in their magnitude impact the pandemic dynamics. In this study, we used a spatial extension of the SEIR-type epidemiological model to simulate and predict the 4-week number of COVID-19 cases in the Charlotte-Concord-Gastonia Metropolitan Statistical Area (MSA), USA. We incorporated a variety of covariates, including mobility, pharmaceutical, and non-pharmaceutical interventions, demographics, and weather data to improve the model's predictive performance. We predicted the number of COVID-19 cases for up to four weeks in the 10 counties of the studied MSA simultaneously over the time period 29 March 2020 to 13 March 2021, and compared the results with the reported number of cases using the root-mean-squared error (RMSE) metric. Our results highlight the importance of spatial heterogeneity and spatial interactions among locations in COVID-19 pandemic modeling.

In Spring 2021, the highly transmissible SARS-CoV-2 Delta variant began to cause increases in cases, hospitalizations, and deaths in parts of the United States. At the time, with slowed vaccination uptake, this novel variant was expected to increase the risk of pandemic resurgence in the US in summer and fall 2021. As part of the COVID-19 Scenario Modeling Hub, an ensemble of nine mechanistic models produced 6-month scenario projections for July-December 2021 for the United States. These projections estimated substantial resurgences of COVID-19 across the US resulting from the more transmissible Delta variant, projected to occur across most of the US, coinciding with school and business reopening. The scenarios revealed that reaching higher vaccine coverage in July-December 2021 reduced the size and duration of the projected resurgence substantially, with the expected impacts was largely concentrated in a subset of states with lower vaccination coverage. Despite accurate projection of COVID-19 surges occurring and timing, the magnitude was substantially underestimated 2021 by the models compared with the of the reported cases, hospitalizations, and deaths occurring during July-December, highlighting the continued challenges to predict the evolving COVID-19 pandemic. Vaccination uptake remains critical to limiting transmission and disease, particularly in states with lower vaccination coverage. Higher vaccination goals at the onset of the surge of the new variant were estimated to avert over 1.5 million cases and 21,000 deaths, although may have had even greater impacts, considering the underestimated resurgence magnitude from the model., Competing Interests: ST, CS, MQ, LM, RB, KS, EH, LC, JL, JK, HH, MK, KT, SW, LS, KR, JL, JD, JK, EL, JP, AH, DK, MC, JD, KM, XX, AP, AV, AS, PP, SV, AA, BL, BK, JO, MO, GH, BH, JC, AV, MM, SH, PB, DM, SC, RP, DJ, JT, MG, TY, SP, JH, RS, MB, MJ, CV No competing interests declared, JL has served as an expert witness on cases where the likely length of the pandemic was of issue, JS and Columbia University disclose partial ownership of SK Analytics. Discloses consulting for BNI, MR reports stock ownership in Becton Dickinson & Co, which manufactures medical equipment used in COVID testing, vaccination, and treatment

Recognizing an urgent need to understand the dynamics of the pandemic's severity, this longitudinal study is conducted to explore the evolution of complex relationships between the COVID-19 pandemic, lockdown measures, and social distancing patterns in a diverse set of 86 countries. Collecting data from multiple sources, a structural equation modeling (SEM) technique is applied to understand the interdependencies between independent variables, mediators, and dependent variables. Results show that lockdown and confinement measures are very effective to reduce human mobility at retail and recreation facilities, transit stations, and workplaces and encourage people to stay home and thereby control COVID-19 transmission at critical times. The study also found that national contexts rooted in socioeconomic and institutional factors influence social distancing patterns and severity of the pandemic, particularly with regard to the vulnerability of people, treatment costs, level of globalization, employment distribution, and degree of independence in society. Additionally, this study portrayed a mutual relationship between the COVID-19 pandemic and human mobility. A higher number of COVID-19 confirmed cases and deaths reduces human mobility and the countries with reduced personal mobility have experienced a deepening of the severity of the pandemic. However, the effect of mobility on pandemic severity is stronger than the effect of pandemic situations on mobility. Overall, the study displays considerable temporal changes in the relationships between independent variables, mediators, and dependent variables considering pandemic situations and lockdown regimes, which provides a critical knowledge base for future handling of pandemics. It has also accommodated some policy guidelines for the authority to control the transmission of COVID-19.

This paper focuses on advancing the traditional association rule mining (ARM) approach to capture the rich, multidimensional and multiscalar context that is anticipated to be associated with residential Motor Vehicle Theft (MVT) across urban environments. We tackle the challenge to materialize complex social and spatial components in the mining process and present a novel interactive visualization based on social network analysis of rules and associations to facilitate the analysis of mined rules. The spatial ARM (SARM) findings successfully identify many socio-spatial associations to MVT prevalence and establish their relative influence on crime outcome in a case study. Also, the analysis provides unique insights to understand the interactive relationships between neighborhood characteristics and environmental features to both high and low MVT and underscores the importance of spatial properties of spillover and neighborhood effects on urban residential MVT prevalence. This work follows the tradition of inductive and abductive learning and presents a promising analysis framework using data mining which can be applied to different applications in social sciences., (Published by Elsevier Inc.)

There is a compelling and pressing need to better understand the temporal dynamics of public sentiment towards COVID-19 vaccines in the US on a national and state-wise level for facilitating appropriate public policy applications. Our analysis of social media data from early February and late March 2021 shows that, despite the overall strength of positive sentiment and despite the increasing numbers of Americans being fully vaccinated, negative sentiment towards COVID-19 vaccines still persists among segments of people who are hesitant towards the vaccine. In this study, we perform sentiment analytics on vaccine tweets, monitor changes in public sentiment over time, contrast vaccination sentiment scores with actual vaccination data from the US CDC and the Household Pulse Survey (HPS), explore the influence of maturity of Twitter user-accounts and generate geographic mapping of tweet sentiments. We observe that fear sentiment remained unchanged in populous states, whereas trust sentiment declined slightly in these same states. Changes in sentiments were more notable among less populous states in the central sections of the US. Furthermore, we leverage the emotion polarity based Public Sentiment Scenarios (PSS) framework, which was developed for COVID-19 sentiment analytics, to systematically posit implications for public policy processes with the aim of improving the positioning, messaging, and administration of vaccines. These insights are expected to contribute to policies that can expedite the vaccination program and move the nation closer to the cherished herd immunity goal.

Background: Mathematical models are powerful tools to study COVID-19. However, one fundamental challenge in current modeling approaches is the lack of accurate and comprehensive data. Complex epidemiological systems such as COVID-19 are especially challenging to the commonly used mechanistic model when our understanding of this pandemic rapidly refreshes. Objective: We aim to develop a data-driven workflow to extract, process, and develop deep learning (DL) methods to model the COVID-19 epidemic. We provide an alternative modeling approach to complement the current mechanistic modeling paradigm. Method: We extensively searched, extracted, and annotated relevant datasets from over 60 official press releases in Hubei, China, in 2020. Multivariate long short-term memory (LSTM) models were developed with different architectures to track and predict multivariate COVID-19 time series for 1, 2, and 3 days ahead. As a comparison, univariate LSTMs were also developed to track new cases, total cases, and new deaths. Results: A comprehensive dataset with 10 variables was retrieved and processed for 125 days in Hubei. Multivariate LSTM had reasonably good predictability on new deaths, hospitalization of both severe and critical patients, total discharges, and total monitored in hospital. Multivariate LSTM showed better results for new and total cases, and new deaths for 1-day-ahead prediction than univariate counterparts, but not for 2-day and 3-day-ahead predictions. Besides, more complex LSTM architecture seemed not to increase overall predictability in this study. Conclusion: This study demonstrates the feasibility of DL models to complement current mechanistic approaches when the exact epidemiological mechanisms are still under investigation., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Chen, Paul, Janies, Murphy, Feng and Thill.)

The ongoing COVID-19 global pandemic is touching every facet of human lives (e.g., public health, education, economy, transportation, and the environment). This novel pandemic and non-pharmaceutical interventions of lockdown and confinement implemented citywide, regionally or nationally are affecting virus transmission, people's travel patterns, and air quality. Many studies have been conducted to predict the diffusion of the COVID-19 disease, assess the impacts of the pandemic on human mobility and on air quality, and assess the impacts of lockdown measures on viral spread with a range of Machine Learning (ML) techniques. This literature review aims to analyze the results from past research to understand the interactions among the COVID-19 pandemic, lockdown measures, human mobility, and air quality. The critical review of prior studies indicates that urban form, people's socioeconomic and physical conditions, social cohesion, and social distancing measures significantly affect human mobility and COVID-19 viral transmission. During the COVID-19 pandemic, many people are inclined to use private transportation for necessary travel to mitigate coronavirus-related health problems. This review study also noticed that COVID-19 related lockdown measures significantly improve air quality by reducing the concentration of air pollutants, which in turn improves the COVID-19 situation by reducing respiratory-related sickness and deaths. It is argued that ML is a powerful, effective, and robust analytic paradigm to handle complex and wicked problems such as a global pandemic. This study also explores the spatio-temporal aspects of lockdown and confinement measures on coronavirus diffusion, human mobility, and air quality. Additionally, we discuss policy implications, which will be helpful for policy makers to take prompt actions to moderate the severity of the pandemic and improve urban environments by adopting data-driven analytic methods., (This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/.)

Social media has become an emerging alternative to opinion polls for public opinion collection, while it is still posing many challenges as a passive data source, such as structurelessness, quantifiability, and representativeness. Social media data with geotags provide new opportunities to unveil the geographic locations of users expressing their opinions. This paper aims to answer two questions: 1) whether quantifiable measurement of public opinion can be obtained from social media and 2) whether it can produce better or complementary measures compared to opinion polls. This research proposes a novel approach to measure the relative opinion of Twitter users towards public issues in order to accommodate more complex opinion structures and take advantage of the geography pertaining to the public issues. To ensure that this new measure is technically feasible, a modeling framework is developed including building a training dataset by adopting a state-of-the-art approach and devising a new deep learning method called Opinion-Oriented Word Embedding. With a case study of tweets on the 2016 U.S. presidential election, we demonstrate the predictive superiority of our relative opinion approach and we show how it can aid visual analytics and support opinion predictions. Although the relative opinion measure is proved to be more robust than polling, our study also suggests that the former can advantageously complement the latter in opinion prediction., Competing Interests: The authors have declared that no competing interests exist.