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52. A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers

Author

de Brouwer, Remco, primary, te Rijdt, Wouter P, additional, Hoorntje, Edgar T, additional, Amin, Ahmad, additional, Asselbergs, Folkert W, additional, Cox, Moniek G P J, additional, van der Heijden, Jeroen F, additional, Hillege, Hans, additional, Karper, Jacco C, additional, Mahmoud, Belend, additional, van der Meer, Peter, additional, Oomen, Anton, additional, te Riele, Anneline S J M, additional, Silljé, Herman H W, additional, Tan, Hanno L, additional, van Tintelen, Jan Peter, additional, van Veldhuisen, Dirk J, additional, Westenbrink, Berend Daan, additional, Wiesfeld, Ans C P, additional, Willems, Tineke P, additional, van der Zwaag, Paul A, additional, Wilde, Arthur A M, additional, de Boer, Rudolf A, additional, and van den Berg, Maarten P, additional

Published
2023
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53. A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers

Author

de Brouwer, Remco, te Rijdt, Wouter P., Hoorntje, Edgar T., Amin, Ahmad, Asselbergs, Folkert W., Cox, Moniek G.P.J., van der Heijden, Jeroen F., Hillege, Hans, Karper, Jacco C., Mahmoud, Belend, van der Meer, Peter, Oomen, Anton, te Riele, Anneline S.J.M., Silljé, Herman H.W., Tan, Hanno L., van Tintelen, Jan Peter, van Veldhuisen, Dirk J., Westenbrink, Berend Daan, Wiesfeld, Ans C.P., Willems, Tineke P., van der Zwaag, Paul A., Wilde, Arthur A.M., de Boer, Rudolf A., van den Berg, Maarten P., de Brouwer, Remco, te Rijdt, Wouter P., Hoorntje, Edgar T., Amin, Ahmad, Asselbergs, Folkert W., Cox, Moniek G.P.J., van der Heijden, Jeroen F., Hillege, Hans, Karper, Jacco C., Mahmoud, Belend, van der Meer, Peter, Oomen, Anton, te Riele, Anneline S.J.M., Silljé, Herman H.W., Tan, Hanno L., van Tintelen, Jan Peter, van Veldhuisen, Dirk J., Westenbrink, Berend Daan, Wiesfeld, Ans C.P., Willems, Tineke P., van der Zwaag, Paul A., Wilde, Arthur A.M., de Boer, Rudolf A., and van den Berg, Maarten P.

Abstract

Phospholamban (PLN; p.Arg14del) cardiomyopathy is an inherited disease caused by the pathogenic p.Arg14del variant in the PLN gene. Clinically, it is characterized by malignant ventricular arrhythmias and progressive heart failure.1,2 Cardiac fibrotic tissue remodelling occurs early on in PLN p.Arg14del carriers.3,4 Eplerenone was deemed a treatment candidate because of its beneficial effects on ventricular remodelling and antifibrotic properties.5,6 We conducted the multicentre randomized trial ‘intervention in PHOspholamban RElated CArdiomyopathy STudy’ (i-PHORECAST) to assess whether treatment with eplerenone of asymptomatic PLN p.Arg14del carriers attenuates disease onset and progression.

Published
2023

54. A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers

Author

Cardiologie, Team Medisch, Team Onderzoek, Circulatory Health, Onderzoek Device, Genetica, Genetica Groep Van Tintelen, Child Health, de Brouwer, Remco, te Rijdt, Wouter P., Hoorntje, Edgar T., Amin, Ahmad, Asselbergs, Folkert W., Cox, Moniek G.P.J., van der Heijden, Jeroen F., Hillege, Hans, Karper, Jacco C., Mahmoud, Belend, van der Meer, Peter, Oomen, Anton, te Riele, Anneline S.J.M., Silljé, Herman H.W., Tan, Hanno L., van Tintelen, Jan Peter, van Veldhuisen, Dirk J., Westenbrink, Berend Daan, Wiesfeld, Ans C.P., Willems, Tineke P., van der Zwaag, Paul A., Wilde, Arthur A.M., de Boer, Rudolf A., van den Berg, Maarten P., Cardiologie, Team Medisch, Team Onderzoek, Circulatory Health, Onderzoek Device, Genetica, Genetica Groep Van Tintelen, Child Health, de Brouwer, Remco, te Rijdt, Wouter P., Hoorntje, Edgar T., Amin, Ahmad, Asselbergs, Folkert W., Cox, Moniek G.P.J., van der Heijden, Jeroen F., Hillege, Hans, Karper, Jacco C., Mahmoud, Belend, van der Meer, Peter, Oomen, Anton, te Riele, Anneline S.J.M., Silljé, Herman H.W., Tan, Hanno L., van Tintelen, Jan Peter, van Veldhuisen, Dirk J., Westenbrink, Berend Daan, Wiesfeld, Ans C.P., Willems, Tineke P., van der Zwaag, Paul A., Wilde, Arthur A.M., de Boer, Rudolf A., and van den Berg, Maarten P.

Published
2023

55. A Systematic Analysis of the Clinical Outcome Associated with Multiple Reclassified Desmosomal Gene Variants in Arrhythmogenic Right Ventricular Cardiomyopathy Patients

Author

Arts Assistenten Cardiologie, Genetica Sectie Genoomdiagnostiek, Circulatory Health, Cardiologie, Team Medisch, Onderzoek Precision medicine, Genetica Groep Van Tintelen, Cancer, Child Health, Nagyova, Emilia, Hoorntje, Edgar T, Rijdt, Wouter P Te, Bosman, Laurens P, Syrris, Petros, Protonotarios, Alexandros, Elliott, Perry M, Tsatsopoulou, Adalena, Mestroni, Luisa, Taylor, Matthew R G, Sinagra, Gianfranco, Merlo, Marco, Wada, Yuko, Horie, Minoru, Mogensen, Jens, Christensen, Alex H, Gerull, Brenda, Song, Lei, Yao, Yan, Fan, Siyang, Saguner, Ardan M, Duru, Firat, Koskenvuo, Juha W, Cruz Marino, Tania, Tichnell, Crystal, Judge, Daniel P, Dooijes, Dennis, Lekanne Deprez, Ronald H, Basso, Cristina, Pilichou, Kalliopi, Bauce, Barbara, Wilde, Arthur A M, Charron, Philippe, Fressart, Véronique, van der Heijden, Jeroen F, van den Berg, Maarten P, Asselbergs, Folkert W, James, Cynthia A, Jongbloed, Jan D H, Harakalova, Magdalena, van Tintelen, J Peter, Arts Assistenten Cardiologie, Genetica Sectie Genoomdiagnostiek, Circulatory Health, Cardiologie, Team Medisch, Onderzoek Precision medicine, Genetica Groep Van Tintelen, Cancer, Child Health, Nagyova, Emilia, Hoorntje, Edgar T, Rijdt, Wouter P Te, Bosman, Laurens P, Syrris, Petros, Protonotarios, Alexandros, Elliott, Perry M, Tsatsopoulou, Adalena, Mestroni, Luisa, Taylor, Matthew R G, Sinagra, Gianfranco, Merlo, Marco, Wada, Yuko, Horie, Minoru, Mogensen, Jens, Christensen, Alex H, Gerull, Brenda, Song, Lei, Yao, Yan, Fan, Siyang, Saguner, Ardan M, Duru, Firat, Koskenvuo, Juha W, Cruz Marino, Tania, Tichnell, Crystal, Judge, Daniel P, Dooijes, Dennis, Lekanne Deprez, Ronald H, Basso, Cristina, Pilichou, Kalliopi, Bauce, Barbara, Wilde, Arthur A M, Charron, Philippe, Fressart, Véronique, van der Heijden, Jeroen F, van den Berg, Maarten P, Asselbergs, Folkert W, James, Cynthia A, Jongbloed, Jan D H, Harakalova, Magdalena, and van Tintelen, J Peter

Published
2023

61. Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy in the Pediatric Population: Clinical Characterization and Comparison With Adult-Onset Disease

Author

te Riele, Anneline S.J.M., James, Cynthia A., Sawant, Abhishek C., Bhonsale, Aditya, Groeneweg, Judith A., Mast, Thomas P., Murray, Brittney, Tichnell, Crystal, Dooijes, Dennis, van Tintelen, J. Peter, Judge, Daniel P., van der Heijden, Jeroen F., Crosson, Jane, Hauer, Richard N.W., Calkins, Hugh, and Tandri, Harikrishna

Published
2015
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65. Towards a Science of Scaling for Urban Climate Action and Governance.

Author

van der Heijden, Jeroen

Subjects
*URBAN climatology, *CLIMATE change mitigation, *CITIES & towns
Abstract

The scaling of urban climate action and its governance is rapidly becoming a central focus in the urban climate governance literature and policy debates. Building on the broader scaling literature and inspired by related initiatives in other fields, this article calls for the development of a systematic "science of scaling" for urban climate governance. Such a science of scaling may help to give a better understanding of how well-performing urban climate action and its governance can be multiplied, accelerated and broadened (ie horizontal and vertical scaling and scaling out, up and down), and it may help to uncover scaling trajectories towards systemic change in cities (ie deep scaling). [ABSTRACT FROM AUTHOR]

Published
2023
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74. An evidence synthesis of the academic regulatory failure literature

Author

van der Heijden, Jeroen and Vernon, Nicola

Subjects
regulatory failure, public regulation, Public Affairs, Public Policy and Public Administration, Social and Behavioral Sciences, public governance
Abstract

Regulatory failure is much talked about but little understood. Discussions about regulatory failure are often about different understandings of what can be expected of regulatory governance and public regulation. The rhetoric of regulatory failure (typically a blame game) easily (and often) overshadows the analytical explanation of it (Baldwin, Cave, & Lodge, 2012, Chapter 5; Breyer, 1979; Wilson, 1984). As a result, it remains unknown: - What types of failure can be distinguished from the evidence base of the academic literature on regulatory failure; - Under what circumstances regulation is likely to fail and how it fails; - What strategies are available and have been proven successful in the prevention of regulatory failure The aim of this evidence synthesis is to synthesize the evidence base of the academic regulatory failure literature and evaluate the effectiveness (and lack thereof) of strategies to prevent regulatory failure in real-world situations. To this end, this evidence synthesis will answer the following questions: 1. Under what circumstance, when, and how is regulation likely to fail? 2. What evidence-based typology can be distilled from the regulatory failure literature? 3. What strategies are applied by governments and other regulators to prevent regulatory failure and with what level of success? 4. For questions 1 and 3, if heterogeneity is found in studies on regulatory failure: What is the role of context on the occurrence and prevention of regulatory failure?

Published
2022
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77. Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy According to Revised 2010 Task Force Criteria With Inclusion of Non-Desmosomal Phospholamban Mutation Carriers

Author

Groeneweg, Judith A., van der Zwaag, Paul A., Olde Nordkamp, Louise R.A., Bikker, Hennie, Jongbloed, Jan D.H., Jongbloed, Roselie, Wiesfeld, Ans C.P., Cox, Moniek G.P.J., van der Heijden, Jeroen F., Atsma, Douwe E., de Boer, Karin, Doevendans, Pieter A., Vink, Aryan, van Veen, Toon A.B., Dooijes, Dennis, van den Berg, Maarten P., Wilde, Arthur A.M., van Tintelen, J. Peter, and Hauer, Richard N.

Published
2013
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80. Compound urban crises

Author

Environmental Governance, Govern.of Urban Dynamics and Transitions, Global Sustainability Governance, Westman, Linda, Patterson, James, Macrorie, Rachel, Orr, Christopher, Ashcraft, Catherine, Castan Broto, Vanesa, Dolan, Dana, Gupta, Mukesh, van der Heijden, Jeroen, Hickmann, Thomas, Hobbins, Robert, Papin, Marielle, Robin, Enora, Rosan, Christina, Colen Ladeia Torrens, Jonas, Webb, Robert, Environmental Governance, Govern.of Urban Dynamics and Transitions, Global Sustainability Governance, Westman, Linda, Patterson, James, Macrorie, Rachel, Orr, Christopher, Ashcraft, Catherine, Castan Broto, Vanesa, Dolan, Dana, Gupta, Mukesh, van der Heijden, Jeroen, Hickmann, Thomas, Hobbins, Robert, Papin, Marielle, Robin, Enora, Rosan, Christina, Colen Ladeia Torrens, Jonas, and Webb, Robert

Published
2022

81. A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy

Author

Cadrin-Tourigny, Julia, Bosman, Laurens P., Nozza, Anna, Wang, Weijia, Tadros, Rafik, Bhonsale, Aditya, Bourfiss, Mimount, Fortier, Annik, Lie, Oyvind H., Saguner, Ardan M., Svensson, Anneli, Andorin, Antoine, Tichnell, Crystal, Murray, Brittney, Zeppenfeld, Katja, van den Berg, Maarten P., Asselbergs, Folkert W., Wilde, Arthur A. M., Krahn, Andrew D., Talajic, Mario, Rivard, Lena, Chelko, Stephen, Zimmerman, Stefan L., Kamel, Ihab R., Crosson, Jane E., Judge, Daniel P., Yap, Sing-Chien, van der Heijden, Jeroen F., Tandri, Harikrishna, Jongbloed, Jan D. H., Guertin, Marie-Claude, van Tintelen, J. Peter, Platonov, Pyotr G., Duru, Firat, Haugaa, Kristina H., Khairy, Paul, Hauer, Richard N. W., Calkins, Hugh, te Riele, Anneline S. J. M., James, Cynthia A., Cadrin-Tourigny, Julia, Bosman, Laurens P., Nozza, Anna, Wang, Weijia, Tadros, Rafik, Bhonsale, Aditya, Bourfiss, Mimount, Fortier, Annik, Lie, Oyvind H., Saguner, Ardan M., Svensson, Anneli, Andorin, Antoine, Tichnell, Crystal, Murray, Brittney, Zeppenfeld, Katja, van den Berg, Maarten P., Asselbergs, Folkert W., Wilde, Arthur A. M., Krahn, Andrew D., Talajic, Mario, Rivard, Lena, Chelko, Stephen, Zimmerman, Stefan L., Kamel, Ihab R., Crosson, Jane E., Judge, Daniel P., Yap, Sing-Chien, van der Heijden, Jeroen F., Tandri, Harikrishna, Jongbloed, Jan D. H., Guertin, Marie-Claude, van Tintelen, J. Peter, Platonov, Pyotr G., Duru, Firat, Haugaa, Kristina H., Khairy, Paul, Hauer, Richard N. W., Calkins, Hugh, te Riele, Anneline S. J. M., and James, Cynthia A.

Abstract

Aims Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a model for individualized prediction of incident VA/SCD in ARVC patients. Methods and results Five hundred and twenty-eight patients with a definite diagnosis and no history of sustained VAs/SCD at baseline, aged 38.2 +/- 15.5 years, 44.7% male, were enrolled from five registries in North America and Europe. Over 4.83 (interquartile range 2.44-9.33) years of follow-up, 146 (27.7%) experienced sustained VA, defined as SCD, aborted SCD, sustained ventricular tachycardia, or appropriate implantable cardioverter-defibrillator (ICD) therapy. A prediction model estimating annual VA risk was developed using Cox regression with internal validation. Eight potential predictors were pre-specified: age, sex, cardiac syncope in the prior 6 months, non-sustained ventricular tachycardia, number of premature ventricular complexes in 24 h, number of leads with T-wave inversion, and right and left ventricular ejection fractions (LVEFs). All except LVEF were retained in the final model. The model accurately distinguished patients with and without events, with an optimism-corrected C-index of 0.77 [95% confidence interval (CI) 0.73-0.81] and minimal over-optimism [calibration slope of 0.93 (95% CI 0.92-0.95)]. By decision curve analysis, the clinical benefit of the model was superior to a current consensus-based ICD placement algorithm with a 20.3% reduction of ICD placements with the same proportion of protected patients (P < 0.001). Conclusion Using the Largest cohort of patients with ARVC and no prior VA, a prediction model using readily available clinical parameters was devised to estimate VA risk and guide decisions regarding primary prevention ICDs (www.arvcrisk.com)., Funding Agencies|Canadian Heart Rhythm Society George Mines Traveling Fellowship; Montreal Heart Institute Foundation; Fondation LeducqLeducq Foundation [16 CVD 02]; Dutch Heart FoundationNetherlands Heart Foundation [2015T058, CVON2015-12 eDETECT, 2012-10 PREDICT]; Netherlands Organisation for Scientific ResearchNetherlands Organization for Scientific Research (NWO) [040.11.586]; Netherlands Heart Institute [06901]; Swiss National Science FoundationSwiss National Science Foundation (SNSF)European Commission [320030_160327]; UMC Utrecht 2017 Alexandre Suerman Stipend; UMC Utrecht Fellowship Clinical Research Talent; European Unions Horizon 2020 research and innovation program under the ERA-NET Co-fund action [680969]; Dr Francis P. Chiaramonte Private Foundation; Leyla Erkan Family Fund for ARVD Research; Dr Satish, Rupal, and Robin Shah ARVD Fund at Johns Hopkins; Bogle Foundation; Healing Hearts Foundation; Campanella family; Patrick J. Harrison Family; Peter French Memorial Foundation; Wilmerding Endowments; Georg und Bertha Schwyzer-Winiker Foundation; Baugarten Foundation; Swiss Heart Foundation; Leonie-Wild Foundation; Marvin and Philippa Carsley Chair of Medicine; UCL Hospitals NIHR Biomedical Research Centre

Published
2022
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82. Comparing clinical performance of current implantable cardioverter-defibrillator implantation recommendations in arrhythmogenic right ventricular cardiomyopathy

Author

Bosman, Laurens P., Nielsen Gerlach, Claire L., Cadrin-Tourigny, Julia, Orgeron, Gabriela, Tichnell, Crystal, Murray, Brittney, Bourfiss, Mimount, Van Der Heijden, Jeroen F., Yap, Sing Chien, Zeppenfeld, Katja, Van Den Berg, Maarten P., Wilde, Arthur A.M., Asselbergs, Folkert W., Tandri, Hariskrishna, Calkins, Hugh, Van Tintelen, J. Peter, James, Cynthia A., Te Riele, Anneline S.J.M., Bosman, Laurens P., Nielsen Gerlach, Claire L., Cadrin-Tourigny, Julia, Orgeron, Gabriela, Tichnell, Crystal, Murray, Brittney, Bourfiss, Mimount, Van Der Heijden, Jeroen F., Yap, Sing Chien, Zeppenfeld, Katja, Van Den Berg, Maarten P., Wilde, Arthur A.M., Asselbergs, Folkert W., Tandri, Hariskrishna, Calkins, Hugh, Van Tintelen, J. Peter, James, Cynthia A., and Te Riele, Anneline S.J.M.

Abstract

Aims: Arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have an increased risk of ventricular arrhythmias (VA). Four implantable cardioverter-defibrillator (ICD) recommendation algorithms are available The International Task Force Consensus ('ITFC'), an ITFC modification by Orgeron et al. ('mITFC'), the AHA/HRS/ACC guideline for VA management ('AHA'), and the HRS expert consensus statement ('HRS'). This study aims to validate and compare the performance of these algorithms in ARVC. Methods and results: We classified 617 definite ARVC patients (38.5 ± 15.1 years, 52.4% male, 39.2% prior sustained VA) according to four algorithms. Clinical performance was evaluated by sensitivity, specificity, ROC-analysis, and decision curve analysis for any sustained VA and for fast VA (>250 b.p.m.). During 6.4 [2.8-11.5] years follow-up, 282 (45.7%) patients experienced any sustained VA, and 63 (10.2%) fast VA. For any sustained VA, ITFC and mITFC provide higher sensitivity than AHA and HRS (94.0-97.8% vs. 76.7-83.5%), but lower specificity (15.9-32.0% vs. 42.7%-60.1%). Similarly, for fast VA, ITFC and mITFC provide higher sensitivity than AHA and HRS (95.2-97.1% vs. 76.7-78.4%) but lower specificity (42.7-43.1 vs. 76.7-78.4%). Decision curve analysis showed ITFC and mITFC to be superior for a 5-year sustained VA risk ICD indication threshold between 5-25% or 2-9% for fast VA. Conclusion: The ITFC and mITFC provide the highest protection rates, whereas AHA and HRS decrease unnecessary ICD placements. ITFC or mITFC should be used if we consider the 5-year threshold for ICD indication to lie within 5-25% for sustained VA or 2-9% for fast VA. These data will inform decision-making for ICD placement in ARVC.

Published
2022

83. COMPARE LAAO:Rationale and design of the randomized controlled trial 'COMPARing Effectiveness and safety of Left Atrial Appendage Occlusion to standard of care for atrial fibrillation patients at high stroke risk and ineligible

Author

Huijboom, Marina, Maarse, Moniek, Aarnink, Errol, van Dijk, Vincent, Swaans, Martin, van der Heijden, Jeroen, IJsselmuiden, Sander, Folkeringa, Richard, Blaauw, Yuri, Elvan, Arif, Stevenhagen, Jeroen, Vlachojannis, George, van der Voort, Pepijn, Westra, Sjoerd, Chaldoupi, Marisevi, Khan, Muchtiar, de Groot, Joris, van der Kley, Frank, van Mieghem, Nicolas, van Dijk, Ewoud, Dijkgraaf, Marcel, Tijssen, Jan, Boersma, Lucas, Huijboom, Marina, Maarse, Moniek, Aarnink, Errol, van Dijk, Vincent, Swaans, Martin, van der Heijden, Jeroen, IJsselmuiden, Sander, Folkeringa, Richard, Blaauw, Yuri, Elvan, Arif, Stevenhagen, Jeroen, Vlachojannis, George, van der Voort, Pepijn, Westra, Sjoerd, Chaldoupi, Marisevi, Khan, Muchtiar, de Groot, Joris, van der Kley, Frank, van Mieghem, Nicolas, van Dijk, Ewoud, Dijkgraaf, Marcel, Tijssen, Jan, and Boersma, Lucas

Abstract

Background: Left atrial appendage occlusion (LAAO) provides an alternative to oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation (AF). In patients with a long-term or permanent contraindication for OAC randomized controlled trial (RCT) data is lacking. Study objectives: To assess the efficacy and safety of LAAO in AF patients who are ineligible to use OAC. The co-primary efficacy endpoint is (1) time to first occurrence of stroke (ischemic, hemorrhagic, or undetermined) and (2) time to first occurrence of the composite of stroke, transient ischemic attack (TIA), and systemic embolism (SE). The primary safety endpoint is the 30-day rate of peri-procedural complications. Study design: This is a multicenter, investigator-initiated, open-label, blinded endpoint (PROBE), superiority-driven RCT. Patients with AF, a CHA₂DS₂-VASc score ≥2 for men and ≥3 for women and a long-term or permanent contraindication for OAC will be randomized in a 2:1 fashion to the device- or control arm. Patients in the device arm will undergo percutaneous LAAO and will receive post-procedural dual antiplatelet therapy (DAPT) per protocol, while those in the control arm will continue their current treatment consisting of no antithrombotic therapy or (D)APT as deemed appropriate by the primary responsible physician. In this endpoint-driven trial design, assuming a 50% lower stroke risk of LAAO compared to conservative treatment, 609 patients will be followed for a minimum of 1 and a maximum of 5 years. Cost-effectiveness and budget impact analyses will be performed to allow decision-making on reimbursement of LAAO for the target population in the Netherlands. The COMPARE LAAO trial will investigate the clinical superiority in preventing thromboembolic events and cost-effectiveness of LAAO in AF patients with a high thromboembolic risk and a contraindication for OAC use.

Published
2022

84. A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy

Author

Arts Assistenten Cardiologie, Cardiologie zorg, Team Medisch, Circulatory Health, Genetica Groep Van Tintelen, Cancer, Child Health, Genetica, Onderzoek Precision medicine, Cadrin-Tourigny, Julia, Bosman, Laurens P., Nozza, Anna, Wang, Weijia, Tadros, Rafik, Bhonsale, Aditya, Bourfiss, Mimount, Fortier, Annik, Lie, Øyvind H., Saguner, Ardan M., Svensson, Anneli, Andorin, Antoine, Tichnell, Crystal, Murray, Brittney, Zeppenfeld, Katja, Van Den Berg, Maarten P., Asselbergs, Folkert W., Wilde, Arthur A.M., Krahn, Andrew D., Talajic, Mario, Rivard, Lena, Chelko, Stephen, Zimmerman, Stefan L., Kamel, Ihab R., Crosson, Jane E., Judge, Daniel P., Yap, Sing Chien, Van Der Heijden, Jeroen F., Tandri, Harikrishna, Jongbloed, Jan D.H., Guertin, Marie Claude, Van Tintelen, J. Peter, Platonov, Pyotr G., Duru, Firat, Haugaa, Kristina H., Khairy, Paul, Hauer, Richard N.W., Calkins, Hugh, Te Riele, Anneline S.J.M., James, Cynthia A., Arts Assistenten Cardiologie, Cardiologie zorg, Team Medisch, Circulatory Health, Genetica Groep Van Tintelen, Cancer, Child Health, Genetica, Onderzoek Precision medicine, Cadrin-Tourigny, Julia, Bosman, Laurens P., Nozza, Anna, Wang, Weijia, Tadros, Rafik, Bhonsale, Aditya, Bourfiss, Mimount, Fortier, Annik, Lie, Øyvind H., Saguner, Ardan M., Svensson, Anneli, Andorin, Antoine, Tichnell, Crystal, Murray, Brittney, Zeppenfeld, Katja, Van Den Berg, Maarten P., Asselbergs, Folkert W., Wilde, Arthur A.M., Krahn, Andrew D., Talajic, Mario, Rivard, Lena, Chelko, Stephen, Zimmerman, Stefan L., Kamel, Ihab R., Crosson, Jane E., Judge, Daniel P., Yap, Sing Chien, Van Der Heijden, Jeroen F., Tandri, Harikrishna, Jongbloed, Jan D.H., Guertin, Marie Claude, Van Tintelen, J. Peter, Platonov, Pyotr G., Duru, Firat, Haugaa, Kristina H., Khairy, Paul, Hauer, Richard N.W., Calkins, Hugh, Te Riele, Anneline S.J.M., and James, Cynthia A.

Published
2022

85. COMPARE LAAO: Rationale and design of the randomized controlled trial 'COMPARing Effectiveness and safety of Left Atrial Appendage Occlusion to standard of care for atrial fibrillation patients at high stroke risk and ineligible to use oral anticoagulation therapy'

Author

Team Medisch, Huijboom, Marina, Maarse, Moniek, Aarnink, Errol, van Dijk, Vincent, Swaans, Martin, van der Heijden, Jeroen, IJsselmuiden, Sander, Folkeringa, Richard, Blaauw, Yuri, Elvan, Arif, Stevenhagen, Jeroen, Vlachojannis, George, van der Voort, Pepijn, Westra, Sjoerd, Chaldoupi, Marisevi, Khan, Muchtiar, de Groot, Joris, van der Kley, Frank, van Mieghem, Nicolas, van Dijk, Ewoud, Dijkgraaf, Marcel, Tijssen, Jan, Boersma, Lucas, Team Medisch, Huijboom, Marina, Maarse, Moniek, Aarnink, Errol, van Dijk, Vincent, Swaans, Martin, van der Heijden, Jeroen, IJsselmuiden, Sander, Folkeringa, Richard, Blaauw, Yuri, Elvan, Arif, Stevenhagen, Jeroen, Vlachojannis, George, van der Voort, Pepijn, Westra, Sjoerd, Chaldoupi, Marisevi, Khan, Muchtiar, de Groot, Joris, van der Kley, Frank, van Mieghem, Nicolas, van Dijk, Ewoud, Dijkgraaf, Marcel, Tijssen, Jan, and Boersma, Lucas

Published
2022

86. Clinical Characteristics and Follow-Up of Pediatric-Onset Arrhythmogenic Right Ventricular Cardiomyopathy

Author

Electrofysiologie, CCU Cardiologie, Team Onderzoek, Arts Assistenten Cardiologie, Onderzoek Precision medicine, Cardiologie onderzoek 1, Child Health, Circulatory Health, Regenerative Medicine and Stem Cells, Cardiologie patientenzorg, Genetica, Genetica Sectie Genoomdiagnostiek, Team Medisch, Cancer, Roudijk, Robert W., Verheul, Lisa, Bosman, Laurens P., Bourfiss, Mimount, Breur, Johannes M.P.J., Slieker, Martijn G., Blank, Andreas C., Dooijes, Dennis, van der Heijden, Jeroen F., van den Heuvel, Freek, Clur, Sally Ann, Udink ten Cate, Floris E.A., van den Berg, Maarten P., Wilde, Arthur A.M., Asselbergs, Folkert W., Peter van Tintelen, J., te Riele, Anneline S.J.M., Electrofysiologie, CCU Cardiologie, Team Onderzoek, Arts Assistenten Cardiologie, Onderzoek Precision medicine, Cardiologie onderzoek 1, Child Health, Circulatory Health, Regenerative Medicine and Stem Cells, Cardiologie patientenzorg, Genetica, Genetica Sectie Genoomdiagnostiek, Team Medisch, Cancer, Roudijk, Robert W., Verheul, Lisa, Bosman, Laurens P., Bourfiss, Mimount, Breur, Johannes M.P.J., Slieker, Martijn G., Blank, Andreas C., Dooijes, Dennis, van der Heijden, Jeroen F., van den Heuvel, Freek, Clur, Sally Ann, Udink ten Cate, Floris E.A., van den Berg, Maarten P., Wilde, Arthur A.M., Asselbergs, Folkert W., Peter van Tintelen, J., and te Riele, Anneline S.J.M.

Published
2022

87. Comparing clinical performance of current implantable cardioverter-defibrillator implantation recommendations in arrhythmogenic right ventricular cardiomyopathy

Author

Aios en Stafsecr. Cardiologie, Onderzoek Precision medicine, Team Medisch, Circulatory Health, Genetica, Arts Assistenten Cardiologie, Bosman, Laurens P, Nielsen Gerlach, Claire L, Cadrin-Tourigny, Julia, Orgeron, Gabriela, Tichnell, Crystal, Murray, Brittney, Bourfiss, Mimount, van der Heijden, Jeroen F, Yap, Sing-Chien, Zeppenfeld, Katja, van den Berg, Maarten P, Wilde, Arthur A M, Asselbergs, Folkert W, Tandri, Hariskrishna, Calkins, Hugh, van Tintelen, J Peter, James, Cynthia A, Te Riele, Anneline S J M, Aios en Stafsecr. Cardiologie, Onderzoek Precision medicine, Team Medisch, Circulatory Health, Genetica, Arts Assistenten Cardiologie, Bosman, Laurens P, Nielsen Gerlach, Claire L, Cadrin-Tourigny, Julia, Orgeron, Gabriela, Tichnell, Crystal, Murray, Brittney, Bourfiss, Mimount, van der Heijden, Jeroen F, Yap, Sing-Chien, Zeppenfeld, Katja, van den Berg, Maarten P, Wilde, Arthur A M, Asselbergs, Folkert W, Tandri, Hariskrishna, Calkins, Hugh, van Tintelen, J Peter, James, Cynthia A, and Te Riele, Anneline S J M

Published
2022

89. Multilevel analyses of SCN5A mutations in arrhythmogenic right ventricular dysplasia/cardiomyopathy suggest non-canonical mechanisms for disease pathogenesis

Author

te Riele, Anneline S.J.M., Agullo-Pascual, Esperanza, James, Cynthia A., Leo-Macias, Alejandra, Cerrone, Marina, Zhang, Mingliang, Lin, Xianming, Lin, Bin, Sobreira, Nara L., Amat-Alarcon, Nuria, Marsman, Roos F., Murray, Brittney, Tichnell, Crystal, van der Heijden, Jeroen F., Dooijes, Dennis, van Veen, Toon A.B., Tandri, Harikrishna, Fowler, Steven J., Hauer, Richard N.W., Tomaselli, Gordon, van den Berg, Maarten P., Taylor, Matthew R.G., Brun, Francesca, Sinagra, Gianfranco, Wilde, Arthur A.M., Mestroni, Luisa, Bezzina, Connie R., Calkins, Hugh, Peter van Tintelen, J., Bu, Lei, Delmar, Mario, and Judge, Daniel P.

Published
2017
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91. CE-522-03 LONGITUDINAL PREDICTION OF VENTRICULAR ARRHYTHMIAS IN PATIENTS WITH ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY

Author

Carrick, Richard, primary, Riele, Anneline Te, additional, Gasperetti, Alessio, additional, Bosman, Laurens P., additional, Cadrin-Tourigny, Julia, additional, Tundo, Fabrizio, additional, Pendleton, Kristin, additional, Tichnell, Crystal, additional, van den berg, nicoline P., additional, van der Heijden, Jeroen F., additional, van Tintelen, Peter, additional, Wilde, Arthur A.M., additional, Yap, Sing-Chien, additional, Zeppenfeld, Katja, additional, Calkins, Hugh, additional, James, Cynthia A., additional, and Wu, Katherine C., additional

Published
2022
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92. A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy

Author

Cadrin-Tourigny, Julia, primary, Bosman, Laurens P, additional, Nozza, Anna, additional, Wang, Weijia, additional, Tadros, Rafik, additional, Bhonsale, Aditya, additional, Bourfiss, Mimount, additional, Fortier, Annik, additional, Lie, Øyvind H, additional, Saguner, Ardan M, additional, Svensson, Anneli, additional, Andorin, Antoine, additional, Tichnell, Crystal, additional, Murray, Brittney, additional, Zeppenfeld, Katja, additional, van den Berg, Maarten P, additional, Asselbergs, Folkert W, additional, Wilde, Arthur A M, additional, Krahn, Andrew D, additional, Talajic, Mario, additional, Rivard, Lena, additional, Chelko, Stephen, additional, Zimmerman, Stefan L, additional, Kamel, Ihab R, additional, Crosson, Jane E, additional, Judge, Daniel P, additional, Yap, Sing Chien, additional, van der Heijden, Jeroen F, additional, Tandri, Harikrishna, additional, Jongbloed, Jan D H, additional, Guertin, Marie Claude, additional, van Tintelen, J Peter, additional, Platonov, Pyotr G, additional, Duru, Firat, additional, Haugaa, Kristina H, additional, Khairy, Paul, additional, Hauer, Richard N W, additional, Calkins, Hugh, additional, te Riele, Anneline S J M, additional, and James, Cynthia A, additional

Published
2022
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